Why am I taking virology?Dr. James Maruniak

• 1. You have viruses.• 2. You will give someone your virus.• 3. Someone could die including you from your virus.• 4. These viruses could interfere with your quality of life,

your sex life, and reproductive capability.• 5. You can do something about them.• 6. You will use your knowledge in your professional career.

*

MCB 4503 and MCB 5505 General Virology Monday, January 7, 2015

By the end of today’s class you should 1. know exam times and grading 2. know sources of lecture and exam information 3. know types of exam questions 4. know attendance policy 5. know some of my educational background and virology teaching experience http://entnem.ifas.ufl.edu/maruniak/virology/ https://sites.google.com/site/virologyuf/home 6. have a syllabus 7. know instructors

http://entnem.ifas.ufl.edu/maruniak/virology

http://www.cals.ufl.edu/honors/

MCB 4503 GENERAL VIROLOGY

Instructors: This course is taught by Drs. James E. Maruniak with the following guest lecturers: Polston, Small and Yamamoto. The lectures are Monday, Wednesday and Friday, 8:30 a.m. to 9:20 a.m.

General description: This course is for undergraduate students in microbiology and related disciplines. The course teaches basic information on families of viruses from humans, plants, insects, animals and bacteria. Lectures cover the basic information of the medical, clinical, diagnostic, biotechnological, and molecular aspects of these viruses.

Prerequisites: Any basic course in microbiology, genetics, biochemistry or molecular biology.

Gatorlink Account "All UF students are required to have an active Gatorlink account. You may obtain a Gatorlink account by logging on to http://www.gatorlink.ufl.edu, or by visiting the Circa lab located across from Turlington Hall and signing up.

Textbook: No textbooks are required for the virology course. The textbook at the library is Jawetz et al. Medical Microbiology, 26th Edition, ISBN 978-0-07179-031-4 (eBook* available through UF libraries: http://uf.catalog.fcla.edu/uf.jsp?st=UF031735546&ix=pm&I=0&V=D&pm=1*Please note that you MUST be logged on to UF library website or Gatorlink VPN to access this eBook off-campus)The course will use the internet to search for current information to answer questions during and after class period. Come prepared with your laptop computer and to interact with other students.

Course grade: The course grade will be determined by four exams, each counting 50 points. There are no regular make-up exams. If you miss an exam, one test score can be dropped; however, you can take a comprehensive makeup for one test at the end of the course during the regularly scheduled final exam. The last of four exams will be given on Apr. 16. If you miss the fourth test with an acceptable medical or family excuse, you can take a make-up test during the scheduled final exam. All students must take the fourth or final exam with a passing grade or receive an incomplete grade. The tests questions are multiple choice with one or more answers, fill-in blanks and drawings. Information for tests will be from lectures and handouts. Letter grades are based on the percent of 150 total points: A=100-90%, B+=89.9-88%, B=87.9-80%, C+=79.9-78%, C=77.9-70%, D=69.9-60% and below 60%=E.

MCB 5505 GENERAL VIROLOGY

Instructors: This course is taught by Drs. James E. Maruniak with the following guest lecturers: Polston, Small and Yamamoto. The lectures are Monday, Wednesday and Friday, 8:30 a.m. to 9:20 a.m.

General description: This course is for beginning graduate and honor students in microbiology and related disciplines. The course teaches basic information on families of viruses from humans, plants, insects, animals and bacteria. Lectures cover the basic information of the medical, clinical, diagnostic, biotechnological, and molecular aspects of these viruses.

Prerequisites: Any basic course in microbiology, genetics, biochemistry or molecular biology.

Gatorlink Account "All UF students are required to have an active Gatorlink account. You may obtain a Gatorlink account by logging on to http://www.gatorlink.ufl.edu, or by visiting the Circa lab located across from Turlington Hall and signing up.

Textbook: No textbooks are required for the virology course. The course will use the internet to search for current information to answer questions during and after class period. Come prepared with your laptop computer and to interact with other students. Course grade: The course grade will be determined by four exams, each counting 50 points. There are no regular make-up exams. If you miss an exam, one test score can be dropped; however, you can take a comprehensive makeup for one test at the end of the course during the regularly scheduled final exam. The last of four exams will be given on April 16, 2014. If you miss the fourth test with an acceptable medical or family excuse, you can take a make-up test during the scheduled final exam. All students must take the fourth or final exam with a passing grade or receive an incomplete grade. The test questions are multiple choice with one or more answers. Information for tests will be from lectures, handouts and the course CD. Graduate students are expected to write a portfolio on 5 virus families in a specialty area for their future career and give a 10-12 minute oral presentation in class as a panel discussion (50 points). Letter grades are based on the percent of 200 total points: A=100-90%, B+=89.9-88%, B=87.9-80%, C+=79.9-78%, C=77.9-70%, D=69.9-60% and below 60%=E.

Attendance Policy: All students are expected to attend every class. Attendance policy for this course is based on the guidelines in the Undergraduate Catalog. Students not attending at least one of the first two class meetings will be dropped from the course. Attendance will be taken randomly throughout the semester. Medical or family emergencies must be documented. Academic honesty: When completing registration at the University of Florida, you signed the following statement: “I understand that the University of Florida expects its students to be honest in all their academic work. I agree to adhere to this commitment to academic honesty and understand that my failure to comply with this commitment may result in disciplinary action up to and including expulsion from the University.” I, as a member of the University of Florida faculty, pledge to hold myself to the highest standards of honesty and integrity. UF Counseling Services: Resources are available on campus for students having personal problems or lacking clear academic goals which interfere with their academic performance. These resources include: University Counseling Center, 301 Peabody Hall, 392-1574, 1575. Student Mental Health, Student Health Care Center, 392-1171. Personal counseling, Sexual Assault Recovery Services, Student Health Care Center, 392-1161. Career Resource Center Reitz Union, 392-1601.

Software Use: All faculty, staff and students of the University are required and expected to obey the laws and legal agreements governing software use. Failure to do so can lead to monetary damages and/or criminal penalties for the individual violator. Because such violations are also against University of Florida policies and rules, disciplinary action will also be taken as appropriate. Email: I read email, but because of the volume of University email to me, I do not always get back right away. All University of Florida students are required to have a Gatorlink account that I can use to email you for special announcements.

MCB 4503VirologyClassroom

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CORRECT ANSWERS OF 50 QUESTIONSON A VIROLOGY EXAM

Hey Dr. Maruniak, this is Tim Miller. I took your class this past spring, 2005. I don't do this with many of my professors... well actually, I never have, but now that I

don't have you as a professor anymore, and therefore could not be doing this for "brownie points," I just wanted to let you know how much I enjoyed your class. I usually dread sitting through college classes, especially at 8 in the morning, but I really enjoyed learning in your class. Also, the slides on DVD is really a great learning tool...

I found that when I was taking your tests, I could actually hear your voice in my head going over the information that was being asked about. I don't remember half of the stuff that I've learned in other classes, but I really remember almost everything from Virology.

I ended up with what I consider an easy A, but not because the class or tests were easy, but rather because you presented the information in such a way that it became easy for me.

Anyway, I'm in the process of applying to medical schools and doing well with everything. I'm going to be going to Honduras right after Christmas to do some missionary work: helping to finish building an orphanage, and subsequently moving in many orphaned children and caring for them... Then its off to med school.

I hope all is going well with you and your family. I just wanted to let you know how much I appreciate what you have done for me. I don't think you realize how much you affect your students, but your really have affected my in such a positive way, and I will never forget it, or you. Thank you. Sincerely, Timothy D. Miller Jr.

Carrie Mewha

UF Microbiology & Cell Science graduate

She is from St. Petersburg, Florida, and was the valedictorian of St. Petersburg High School. Mewha was a National Merit Scholar and graduated from the University of Florida with bachelor degrees in microbiology and cell science. Later she went on the Medical School at the University of Miami, and specialized in maternal-fetal medicine.Carrie Ann Mantha (née Mewha) was the Miss Florida USA for 2003, is a licensed Medical Doctor, and now works as an analyst covering biotechnology stocks for Galleon, a New York hedge fund.

http://www.cdc.gov/flu/weekly/downloadimage.htm?w=53

• December 15th, 2012 • 12:28 PM ET

• Hillary Clinton faints, suffers concussion• U.S. Secretary of State Hillary Clinton sustained a concussion after becoming dehydrated and

fainting, a State Department official said.• Clinton had been suffering from a stomach virus at the time, according to a statement on Saturday

from Philippe Reines, deputy assistant secretary of state.• She is being monitored by doctors and is recovering at home. She was never hospitalized, Reines

said.

• Virus Seen in Muscle from Chronic Fatigue Patients• Mass. Woman Sues Over HIV Misdiagnosis• Fewer Women to Need Annual Cervical Tests• Researchers: Pill Stops Spread of Herpes• Flu Deaths Hit Epidemic Level in U.S. • The Offal Truth: People Enjoy Eating Calf Brains• Ark. Officials Limit Sharing Information About Flu Deaths, Citing New U.S. Medical

Privacy Law• Japan Patient Receives HIV-Tainted Blood• Flu Outbreak Strains Demand for Test Kits• South Korean Bird Flu Outbreak Spreads• Expert warns MMR scare could spark measles epidemic in Britain• Flu Shot Unable to Combat Virus Strain• Four Children in Colorado Die From Flu• Green Onions Suspected in Hepatitis Cases• Human Papillomavirus Tied to Oral Cancer• Italy Launches New AIDS Vaccine Trials Based on Tat• New Australian research links breast cancer to a virus• Rules to Stop Monkeypox Spread in U.S. Finalized• Vaccine-Evading Mousepox Virus Created• Churches Say Condoms Don't Stop AIDS• Gene Therapy Did Cause Cancer in Boys• Smallpox Vaccine Could Prevent AIDS

Danny Wuerffel continues recovery from Guillain-Barre syndrome

• December 07, 2011|By Rachel George, Orlando Sentinel• GAINESVILLE — Former Florida QB Danny Wuerffel continues his recovery from

Guillain-Barre syndrome but writes in his latest update that "life is tough."• Wuerffel has been dealing with Guillain-Barre, which causes the immune system to

attack the nerves in response to an infectious illness, since being hospitalized in June. He has posted periodic updates on the website for Desire Street Ministries, where he is the executive director.

• "I've been battling with GBS for over six months now, and the difficulties in my life related to the illness continue to make life much harder than I want," Wuerffel wrote. "Overall, I'm doing better and I'm thankful for the progress."

• A Thanksgiving trip to visit in-laws left him drained, and Wuerffel writes that some days he doesn't have the energy to complete a few simple tasks. Life has seasons, Wuerffel writes, and right now he feels like he's in the winter.

• Wuerffel was diagnosed not long after the unveiling of a statue of him at the UF spring game. The University Athletic Association unveiled bronze statues of Wuerffel and Florida's other Heisman Trophy-winning QBs — Tim Tebow and Steve Spurrier — at that game in April.

Stricken cruise ship docks for cleaning

By JENNIFER KAY, Associated Press Writer

A thorough scrubbing of the Carnival Liberty began Sunday as the ship docked after a virus sickened nearly 700 passengers on a trans-Atlantic cruise.

Fourteen guests and five crew remained ill and in isolation when the ship arrived at Port Everglades, according to a statement released by Carnival Cruise Lines, a brand of Carnival Corp. Some passengers were escorted off the ship in wheelchairs by crew wearing blue gloves.

Preliminary tests identified the source of the outbreak as the highly contagious norovirus, which had struck several guests just before they boarded the cruise Nov. 3 in Rome, Carnival officials said. More than 530 guests and 140 crew reported to the ship's infirmary with similar symptoms during the 16-day voyage.

Thousands of Britons sickened by virus

Thousands of people in Britain have been sickened by the biggest outbreak of a winter vomiting virus in five years. Doctors estimate that hundreds of thousands of people may be affected by norovirus in the coming days. Dozens of hospital wards across the country have already been closed to try to stop the virus' spread.

"General practitioners are seeing a huge number of cases of patients with the norovirus," said Steve Field, chairman of the Royal College of General Practitioners.Norovirus is the most common stomach bug in the United Kingdom, and its incidence typically spikes during the winter.

"The norovirus season has started uncharacteristically early compared to other years," said the Health Protection Agency in a statement. Most cases go unreported, and the agency estimates that for every case, there are 1,500 others.

Symptoms include nausea, projectile vomiting, diarrhea, fever and muscle pain. Most people recover within two days without treatment, though the virus can be more serious in the very young or the elderly.

The Health Protection Agency estimates that there are between 600,000 and 1 million cases of norovirus in the U.K. every year. Numbers of cases vary every year, and the agency said that this year's figures are not yet exceptional.

Virus leads to Federer withdrawal

World number one Roger Federer has withdrawn from the Kooyong Classic in Melbourne because of a stomach virus. The eight-man exhibition tournament is a warm-up for the Australian Open which begins on 14 January, with Federer hoping to retain his title. "After arriving in Australia I came down with a stomach virus and it continued to get worse," said Federer.

Polo returns to Boca Raton area without worries about equine virusMatch opens season free of last year's worries about equine virus

By Chrystian Tejedor | South Florida Sun-Sentinel January 7, 2008

West Boca - Horse hoofs kicked up patches of dark green sod Sunday.

Men with mallets whacked a tiny white ball up and down the field, and Tom Oxley's voice blared over loudspeakers.

Polo season has returned to the Royal Palm Polo Club west of Boca Raton.

"I look forward to this from now to the middle of April," said longtime spectator John Hinckley, of Boca Raton. "Once you're here, you know why people come."

Sunday's John T. Oxley Memorial, played in honor of the Royal Palm Polo Club's builder and Tom Oxley's father, marks the beginning of the January-to-April polo season.

Before the start of the 2007 season, equestrians in Palm Beach County were fretting over an equine herpes virus outbreak in Wellington that killed at least six horses and infected seven others across the state. The village and the Royal Palm Polo Club went under a voluntary quarantine that ended just as the season was to begin.

Lauren Fant, left, 18, winces as she has her third and final application of the HPV vaccine administered by nurse Stephanie Pearson at a doctor's office , in Marietta, Ga. This groundbreaking vaccine that prevents cervical cancer in girls is gaining a reputation as the most painful of childhood shots, health experts say.

Glaxo Vaccine Stops Virus Linked to Cancer

LONDON (Reuters) -It's one of the most common cancers in women and kills about a quarter of a million patients each year but scientists said on Friday that a new vaccine could prevent most cases of cervical cancer.

The researchers tested a vaccine that protects women against two strains of the human papillomavirus (HPV) which are linked to more than 70 percent of cervical cancer cases. The vaccine was developed by drugs giant GlaxoSmithKline Plc.

Study Reveals Why Flu Thrives in Winter

Oct 18, 2007 For the first time, scientist have solid evidence suggesting exactly why the flu is so common in winter. A new animal study suggests that the influenza virus' success hinges on low relative humidity and cold temperatures. Such conditions keep the virus more stable and in the air longer than warm, humid conditions, scientists said. And apparently, the frosty weather's role is more important than that of the human body in helping the virus thrive.

"We've always thought the immune system wasn't as active during the winter, but that doesn't really seem to be the case," said study coauthor Peter Palese, a virologist at the Mount Sinai School of Medicine in New York City.

When we cough or sneeze, tiny droplets of water enter the air and hang around until they drop to the ground—or an unsuspecting passerby breathes them in. Once inside our airways, any flu viruses that have hitched a ride on the droplets can launch an attack.

"We found that the flu's transmission period is much, much longer when temperatures and humidity levels are low," Palese told LiveScience.

Henson Returns To Aggies BenchHe'll Coach From A Wheelchair

Monday, January 03, 2005 -- The "Lou Do" is back.

Lou Henson will return to the Aggies bench on Saturday to coach New Mexico St. against North Texas in the Sun Belt Conference opener.

Henson, 22 victories short of becoming only the fifth Division I basketball coach with 800, was stricken with viral encephalitis three months ago. The disease - an acute inflammation of the brain- caused paralysis in Henson's right leg.

He'll eventually fully recover but for this season Henson will coach from a wheelchair.

N.H. warns dozens at risk of meningitis January 4, 2007 More than 80 people in three states may be at risk for meningitis after coming into contact with a University of New Hampshire student who died of the illness this week, health officials said.

The college student, 21-year-old Danielle Thompson, had been in her home state of Maine, as well as in Massachusetts and New Hampshire, in the 10 days before she was admitted to a Dover hospital. She died of bacterial meningitis on Wednesday.

Health and Human Services Commissioner John Stephen said the state has identified 29 people in New Hampshire and 55 in Maine who should receive antibiotics. Officials were still tracking down how many people Thompson visited in Massachusetts.

No one has yet shown symptoms, Stephen said.

Bacterial meningitis can be spread through saliva, creating the most risk for people who shared food or drinks, kissed or used the same eating utensils. It causes an infection of fluid in the spinal cord and surrounding the brain, with symptoms include high fever, headache and stiff neck.

"This case underscores just how serious this illness can be," Stephen said.

In Rhode Island, epidemiologists from the U.S. Centers for Disease Control and Prevention are working with state officials investigating a possible case of meningitis and three cases of encephalitis that surfaced in public school children. One second-grader in Warwick died from encephalitis that was brought on by "walking pneumonia.“

Signs and symptoms of walking pneumonia usually include a severe cough, fever, abdominal pain, headaches, and chills.

Mycoplasma pneumoniae, the organism that causes walking pneumonia, can be contagious if contact with the infected person is prolonged. Walking pneumonia is transmitted through airborne droplets, which are dispersed when a person talks, sneezes, coughs or laughs.

Condoms urged in prisons to curb AIDS in blacks

• By Will Dunham Thu Nov 16, 2007 • U.S. prisons should make condoms available to inmates and test for HIV as part of a

broader effort to curb the spread of AIDS among blacks, hit disproportionately hard by the incurable disease, experts urged on Thursday.

• The National Minority AIDS Council advocacy group, backed by U.S. black lawmakers and medical leaders, issued a series of recommendations aimed at U.S. policymakers to slow the epidemic among blacks, 10 times more likely than whites to have AIDS.

• "In 2006, AIDS in America is a black disease," said Phill Wilson, executive director of the Black AIDS Institute in Los Angeles.

• With U.S. black men seven times more likely than whites and three times more likely than Latinos to be imprisoned, the council's report said incarceration has become "one of the most important drivers of HIV infection among African-Americans."

• More than half of new U.S. HIV infections are in blacks, according to the Centers for Disease Control and Prevention.

Serial HIV Assault Verdict Expected

OLYMPIA, Wash. - November 5, 2004

A verdict will be announced Monday in the trial of a man charged with intentionally exposing 17 women to HIV, a county judge said.

"Sex machine," "Russian roulette" and "sex addiction" were among the phrases lawyers used Thursday in 2 1/2 hours of closing arguments in the case of Anthony E. Whitfield, 32, of Lacey.

Whitfield, formerly of Oklahoma City, is charged with 17 counts of first-degree assault with sexual motivation, witness tampering and violating a court protection order. He could be sentenced to 137 to 182 years in prison if convicted on all counts.

Five of the women cited in the case have been infected with the virus that causes AIDS.

Tuesday January 8, 2002

University Study: Body Piercing a Pain for Some

ROCHESTER, Minn. (Reuters) - Piercings of navels, ears and other parts of thebody caused problems from infections to bleeding for nearly one in five piercedstudents at a college in New York state, school researchers said on Tuesday.

About half last year's student body at Pace University in Pleasantville, NewYork, had piercings and one quarter had tattoos and doctors there decided tosurvey students to gauge the medical implications.

Bacterial infection was the most commonly reported problem, followed by bleedingand injury or tearing at the site of the piercing, based on the survey of 454undergraduates.

Among female students with piercing other than their earlobes, the navel was themost common site, followed by the rest of the ear. For men, the ear was mostpopular. Male athletes commonly had tattoos.

Though there were no reported medical complications from the students' tattoos,the report said the bad news may come later when infections with hepatitis B orC or the AIDS virus become apparent.

``If our prevalence and complication rates are representative for this agegroup, these morbid events comprise a considerable demand on and cost to thehealth care system,'' study author Dr. Lester Mayers of Pace University'sDivision of Sports Medicine wrote in the January issue of the journal, ''MayoClinic Proceedings.''

Common Virus Ups Risk of Problems in Heart Patients  NEW YORK (Reuters) - Tue, Dec 24, 2002 People with heart disease appear to be at a slightly increased risk of life-threatening cardiovascular problems if they are infected with a common virus belonging to the herpesvirus family, according to new research.  Among more than 3,000 people with heart disease, those whose blood carried antibodies--a sign of current or past infection--to cytomegalovirus (CMV) showed a 24% increased risk of experiencing a heart attack or stroke, or of dying from cardiovascular disease within 4-1/2 years.

DRUG WATCH 3-18-2002: CIDOFOVIR Gilead Sciences of Foster City, CA, has developed the antiviral drug cidofovir as an intravenous injectable liquid (Vistide) for treating cytomegalovirus (CMV) retinitis, a sight-threatening infection of the inner eye, and as a topical gel (Forvade) for treating herpes simplex blisters and sores that do not respond to standard acyclovir (Zovirax) treatment.  The gel has also been studied for treating genital warts caused by human papillomavirus infection, for molluscum contagiosum and for Kaposi’s sarcoma lesions.

Herpes Infections Common Among Lesbians

Nearly half the women (46 percent) who participated in the study were positive for HSV-1, which is the usual cause of "cold sores," the report indicates, and 7.9 percent were positive for HSV-2, which causes genital infections.

The study is the first to report on HSV prevalence in this group specifically, Dr. Jeanne M. Marrazzo from Harborview Medical Center, Seattle, Washington told Reuters Health. Marrazzo and colleagues obtained medical and sexual histories from 392 women (including both members of 71 couples) who reported sex with another woman within the preceding year, and tested their blood for HSV-1 and HSV-2 antibodies.

Most of the women (80 percent) reported having had sex with a man at some time, and 28 percent had sex with a man in the previous year. Among 257 women who self-identified as lesbian, the corresponding figures were 73 percent and 8.6 percent.

"This means that routine acquisition of chronic viral sexually transmitted diseases, like herpes, human papillomavirus (HPV), HIV, and hepatitis B, can occur at the same rate as in strictly heterosexual women," Marrazzo said.

She says health care providers should keep this in mind. "Providers should really assume nothing when a woman says 'I'm a lesbian' -- at least in terms of prior viral sexually transmitted disease acquisition -- until a more complete sexual history is taken."

Jan. 2, 2004 SOURCE: Sexually Transmitted Diseases, December 2003.

Metro State University sophomore Brock Lewis from Denver, receives the FluMist flu vaccination from medical assistant Nicole Ortiz at the Auraria Student Health Center in Denver.

Brenda Gonzales, who is 7 months pregnant, receives a flu shot at the Maple Clinic in Dallas. Health officials are monitoring a surge of flu cases involving pregnant women, some of whom were so sick they had to be hospitalized. The increase is calling attention to yet another group at serious risk of the flu. The local upswing has been concentrated at Parkland Health and Hospital System in Dallas, where 80 pregnant women have been diagnosed with the flu since early October.

Sun 7 Jan 2007 Parents block plans to vaccinate nine-year-olds against sex virusBRIAN BRADY WESTMINSTER EDITORWORRIED parents have blocked government plans to vaccinate girls as young as nine against a sexually-transmitted virus that can cause cervical cancer, Scotland on Sunday can reveal.

Health chiefs have abandoned proposals to offer the jab against human papilloma virus (HPV) to primary school children after parents complained that it was inappropriate for girls of such a young age.

Scotland on Sunday revealed last summer that ministers were considering offering the jab to children in a desperate attempt to stop the "epidemic" in cervical cancer. The proposals for a nationwide scheme followed successful trials of a new vaccine in Glasgow.

But ministers have now been forced to concentrate on plans for the treatment on girls of at least 12 - itself a hugely controversial move.

In September, the European Commission licensed the first HPV vaccine, Gardasil, for use by females aged between nine and 26.

But campaigners protested that immunising young girls from HPV, which can cause genital warts and is blamed for up to 70% of cases of cervical cancer, could encourage them to start having sex earlier. The government U-turn came after medical experts who make the final recommendations on the baseline defences against HPV were warned of parents' opposition. The experts also threw out proposals to vaccinate boys against HPV, despite evidence that they can transmit the virus through sexual contact.