WSSFNQuadrennial MeetingMay 27-30, 2013Hotel Nikko TokyoTokyo, Japan

Jointly sponsored by the:American Association of Neurological Surgeons (AANS)

in collaboration with the:Japan Brain Foundation and theTokyo Convention & Visitors Bureau

Supported by the Japanese Neurological Society

www.wssfn.org

wssfnWorld Society for Stereotacticand Functional Neurosurgery

wssfnWorld Society for Stereotacticand Functional Neurosurgery

Dear Colleagues and Guests of the WSSFN,

Welcome to the 16th Quadrennial Meeting of the World Society for Stereotactic and Functional

Neurosurgery! Our society president, Takaomi Taira, other WSSFN officers, and my scientific program

co‑chair Moji Hodaie have all worked with me to prepare a program that we are sure will be of great

interest and stimulate much discussion.

This is a most exciting time for the WSSFN. As you all know there is an intense focus on stereotactic and

functional neurosurgery the world over, and our society is on the leading edge of this wave. Since our last

meeting in Toronto in May 2009 the European SSFN joined the WSSFN as partners (joining the American

society in this regard). This also has greatly expanded the readership of our official journal, Stereotactic

and Functional Neurosurgery, whose selectivity and impact factor continue to rise under the editorial

leadership of David Roberts. Our last interim meeting in Cape Town in November 2011 was a great

success, and we invite suggestions for our next event in two years.

Planning the WSSFN program does not occur in a vacuum. Your suggestions after the prior meeting

were very much taken into account. You wanted more debates after the success of those two sessions in

Toronto? This year there are nine Bento Box debates, three on each day of the meeting during lunch. More

time devoted to radiosurgery and psychiatric neurosurgery was added, again based on WSSFN member

feedback. A new feature of this year’s program is a final plenary session at the end of the first two meeting

days in which key features of the scientific program will be summarized. Vigorous discussion by all

attendees is encouraged at these sessions.

Due to the record‑breaking number of abstract submissions this year, we had no choice but to have

separate poster sessions. Please adhere to the scheduled day for your poster display. Some of the most

interesting work at our meetings often is in the posters, so please use the available time to view these and

to interact with the authors. The meeting will conclude with a distinguished plenary session and, lastly,

the awards ceremony for best oral and poster presentations by residents and fellows.

You will enjoy the opening reception and gala dinner at the meeting. First‑time visitors should consider

adding some time, before or after the meeting, to see the city and its environs. Take it from a gaijin, Tokyo

is one of the most interesting and safe cities in the world, and quite easy to navigate.

Thanks for coming and for your support of the WSSFN. Please let us know your thoughts on the meeting

and the society as we continue to grow. Your involvement is welcome and all it takes is enthusiasm and

commitment!

Sincerely yours,

Michael Schulder, MD

Scientific Program Chair and Secretary‑Treasurer, WSSFN

wssfnWorld Society for Stereotacticand Functional NeurosurgeryFaculty

MEETING DIRECTORS Takaomi Taira ‑ Meeting ChairmanMichael Schulder ‑ Scientific Program ChairmanMojgan Hodaie ‑ Scientific Program Co‑chairJoseph Neimat ‑ Meeting Industry Relations ChairmanJoachim Krauss ‑ Meeting Co‑chairmanJin Woo Chang ‑ Meeting Co‑chairmanHiroki Toda ‑ Meeting Co‑chairman/Pre‑meeting Symposium ChairmanOsvaldo Vilela Filho ‑ Meeting Co‑chairman

SPEAKERS AND MODERATORSAviva AboschUniversity of Minnesota Department of NeurosurgeryMinneapolis, USA

Feridun AcarPamukkule UniversityDenizli, Tukey

Ahmed AlkhaniKing Faisal Specialist Hospital and Research CentreRiyadh, Saudi Arabia

Ron L. AltermanBeth Israel Deaconess Medical CenterBoston, USA

Jeffrey ArleBeth Israel Deaconess Medical CenterBoston, USA

Tipu AzizRadcliffe Infirmary Department of NeurosurgeryOxford, UK

Roy BakayRush University Medical CenterChicago, USA

Gordon BaltuchUniversity of Pennsylvania School of MedicinePhiladelphia, USA

Juan BarciaHospital Clínico San CarlosMadrid, Spain

Alim BenabidClinatec CEA GrenobleMeylan, France

Tommy BergenheimUmea UniversityUmea, Sweden

Mark BernsteinUniversity of TorontoToronto, Canada

Jocelyne BlochUniversity Hospital of LausanneLausanne, Switzerland

Patric BlomstedtUniversity Hospital of UmeaUmea, Sweden

Giovanni BroggiInstituto Nazionale NeurologicoMilano, Italy

Brian BrophyRoyal Adelaide HospitalAdelaide, Australia

Stephan ChabardesUniversity Hospital of GrenobleGrenoble, France

Jin Woo ChangYonsei University College of MedicineSeoul, South Korea

Mikhail ChernovTokyo Women’s Medical UniversityTokyo, Japan

Larry ChinSUNY Upstate Medical CenterSyracuse, USA

Volker CoenenFreiburg University Medical CenterFreiburg (i.Br.), Germany

Youssef ComairGilbert and Rose‑Marie Chagoury School of MedicineBeirut, Lebanon

Philippe CornuHôpital Pitié‑SalpêtrièreParis, France

Rees CosgroveRhode Island Hospital OR LifespanProvidence, RI

Terry CoyneSt Andrews and Wesley HospitalsAuchenflower, Australia

Jeff CozzensSouthern Illinois UniversitySchool of MedicineSpringfield, USA

Arthur CukiertClinica de Epilepsia de Sao PauloSao Paulo, Brazil

Isao DateOkayama University Medical SchoolOkayama, Japan

Phillipe DecqHopital BeaujonParis, France

Milind DeogaonkarOhio State University Medical CenterColumbus, USA

Antonio De SallesUCLA Neurosurgery DepartmentLos Angeles, USA

Paresh DoshiJaslok Hospital and Research CentreMumbai, India

Wilhelm EisnerMedical University, InnsbruckInnsbruck, Austria

Jeff EliasUniversity of VirginiaCharlottesville, USA

Sam EljamelNinewells Hospital and Medical SchoolDundee, UK

Emad EskandarHarvard Medical School Massachusetts General HospitalBoston, USA

Graham FieggenUniversity of Cape TownCape Town, South Africa

Denys FontaineCentre Hospitalier Universitaire de NiceNice, France

Kostantinos FountasUniversity of Thessaly, School of MedicineTerpsithea‑Larisa, Greece

Alexandre FranciscoHospital Universitário CajuruPontifical Catholic UniversityCuritiba, Brazil

Angelo FranziniBesta Neurological InstituteMilan, Italy

Itzhak FriedRonald Reagan UCLA Medical CenterLos Angeles, USA

Miroslav GalandaRoosevelt HospitalBanska Bystrica, Slovokia

Steven GillFrenchay HospitalBristol, UK

Robert GoodmanRoosevelt HospitalColumbia University College of Physicians and SurgeonsNew York, USA

Alexander GreenOxford Functional Neurosurgery and Experimental NeurologyOxford, UK

Robert GrossEmory UniversityAtlanta, USA

Jorge GuridiClinica UniversitariaPamplona, Spain

Clement HamaniToronto Western HospitalToronto, Canada

Marwan HarizInstitute of NeurologyLondon, UK

Motohiro HayashiTokyo Women’s Medical UniversityTokyo, Japan

Mojgan HodaieUniversity of TorontoToronto, Canada

Christopher HoneyVancouver General HospitalVancouver, Canada

Tomokatsu HoriTokyo Women´s Medical UniversityTokyo, Japan

Zvi IsraelHadassah University HospitalJerusalem, Israel

Ben JonkerBrain and Mind Research InstituteUniversity of Sydney, Australia

Michael KaplittWeill Cornell Medical CollegeNew York, USA

Yoichi KatayamaNihon University School of MedicineTokyo, Japan

WSSFN Quadrennial Meeting 2013

Kensuke KawaiUniversity of TokyoTokyo, Japan

Takeshi KawaseKeio University School of MedicineTokyo, Japan

Yoshihisa KidaKomaki City HospitalKomaki City, Japan

Moon Chan KimKangnazm St. Mary’s HospitalSeoul, Korea

Zelma KissUniversity of CalgaryCalgary, Canada

Masahito KobayashiSaitama Medical UniversitySaitama, Japan

Takeshi KondohShinsuma General HospitalKobe, Japan

Brian Harris KopellIcahn School of MedicineThe Mount Sinai HospitalNew York City, USA

Joachim KraussMedical University of HannoverHannover, Germany

Paul LarsonUCSF Medical CenterSan Francisco, USA

Jung Kyo LeeDepartment of Neurosurgery Asan Medical CenterSeoul, South Korea

Bengt LinderothKarolinska University HospitalStockholm, Sweden

Christer LindquistBupa Cromwell HospitalLondon, UK

Nir LipsmanUniversity of TorontoToronto, Canada

Andres LozanoUniversity of TorontoToronto, Canada

Guoming LuanSanbo Brain InstituteBeijing, China

Goetz LutjensMedical School HanoverHanover, Germany

Andre MachadoCenter for Neurological RestorationCleveland Clinic Cleveland, USA

George MandyburUniversity of Cincinnati Medical CenterMayfield ClinicCincinnati, USA

Keith MatthewsUniversity of DundeeNinewells Hospital and Medical SchoolDundee, Scotland

Paolo MazzoneASLRMC‑CTO HospitalRoma, Italy

Maximilian MehdornChristian‑Albrechts University of KielKiel, Germany

Bjorn MeyersonKarolinska HospitalStockholm, Sweden

Alon MogilnerNYU Langone Medical CenterNew York City, USA

Elena MoroCHU, Joseph Fourier UniversityGrenoble, France

Nobukazu NakasatoTohoku University School of MedicineSendai, Japan

Atsushi NambuNational Insitute for Physiological SciencesOkazaki, Japan

Jules NazzaroUniversity of Kansas School of MedicineKansas City, USA

Joseph NeimatVanderbilt University Medical CenterNashville, USA

Wai Hoe NgNational Neuroscience InstituteSingapore

Bart NuttinU.Z. GasthuisbergLeuven, Belgium

Taku OchiaiOchiai Neurological ClinicSaitama, Japan

Sun Ha PaekSeoul National University HospitalSeoul, South Korea

Erica PetersenUniversity of Arkansa for Medical SciencesLittle Rock, USA

Fabian PiedimonteSchool of Medicine of the University of Buenos AiresBuenos Aires, Argentina

Julie PilitsisAlbany Medical CenterAlbany, USA

Claudio PolloCentre Hosptalier Universitaires VaudoisLausanne, Switzerland

Dheerendra PrasadRoswell Park Cancer InstituteBuffalo, USA

Jean RegisHôpital d’adulte de la TimoneMarseille, France

Ali RezaiThe Ohio State UniversityColumbus, USA

Erich RichterLouisiana State University School of MedicineNew Orleans, USA

David RobertsDartmouth Hitchcock Medical CenterLebanon, USA

Pantaleo RomanelliBesta Neurological InstituteMilan, Italy

Jeffrey RosenfeldAlfred Hospital and Monash UniversityVictoria, Australia

Sally RothemeyerUniversity of Cape TownCape Town, South Africa

Oren SagherUniversity of Michigan Health CenterAnn Arbor, USA

Damianos SakasEvangelismos HospitalAthens, Greece

Tejas SankarUniversity of AlbertaEdmonton, Canada

Gaston SchechtmannKarolinska Institutet and University HospitalStockholm, Sweden

Michael SchulderHofstra North Shore LIJ School of MedicineManhasset, USA

Rick SchuurmanAcademic Medical CenterAmsterdam, Netherlands

Toru SerizawaTsukiji Neurological ClinicTokyo, Japan

Vladimir ShabalovBurdenko Neurosurgical InstituteMoscow, Russia

Ashwini SharanThomas Jefferson University HospitalPhiladelphia, USA

Karl SillayUniversity of Wisconsin Hospital and ClinicsMadison, USA

Marc SindouHospital Neurologique Pierre WertheimerUniversity of LyonLyon, France

Konstantin SlavinUniversity of Illinois College of Medicine at ChicagoChicago, USA

Byung-chul SonSeoul St. Mary’s HospitalThe Catholic University of KoreaSeoul, South Korea

Roberto SpiegelmannChaim Sheba Medical CenterTel Hashomer, Israel

Bomin SunShanghai Jiao Tong UniversityRui Jin HospitalShanghai, China

Takaomi TairaTokyo Women’s Medical UniversityTokyo, Japan

Manoel TeixeiraHospital Das Clínicas University of Sao Paulo Medical SchoolSao Paulo, Brazil

Travis TierneyBrigham and Women’s HospitalBoston, USA

Hiroki TodaTazuke Kofukai Medical Research Institute and Kitano HospitalOsaka, Japan

Francisco VelascoHospital General de Mexico O.D.Mexico City, Mexico

Osvaldo Vilela-FilhoGoiania Neurological Institute and Medical CenterFederal University of GioasGoiania, Brazil

Ashwin ViswanathanBaylor College of MedicineHouston, USA

Eiju WatanabeJichi Medical UniversityTochigi, Japan

Donald WhitingAllegheny West Penn Health SystemPittsburg, USA

Hemmings WuKatholieke Universiteit LeuvenLeuven, Belgium

Masaaki YamamotoKatsuta HospitalHitachi‑naka, Japan

Wade Huai-che YangTaipei Veterans General HospitalTaipe, Taiwan

Ludvic ZrinzoUCL Insitute of Neurology National Hospital for Neurosurgery and NeurologyLondon, UK

wssfnWorld Society for Stereotacticand Functional NeurosurgeryMonday, May 27, 2013

Monday, May 27, 2013

1:00 ‑ 5:00 PM Workshop S1 International Satellite Symposium on Neuro‑surgery for Psychiatric Disorders Tokyo International Exchange Center ‑ Heisei Plaza

Workshop S2 Microrecording and Intraoperative Monitoring Tokyo International Exchange Center‑ Heisei Plaza

6:30 ‑ 9:00 PMOpening Reception:Promenade Deck Hotel Nikko

Tuesday, May 28, 2013 7:00 AM Registration

Continental Breakfast in meeting rooms

7:15 ‑ 8:15 AM

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Breakfast Seminar I: High Intensity Focused Ultrasound

Moderators: Byung Chul Son/M. Sam Eljamel

• HIFU for Pain: Nir Lipsman

• Movement Disorders: Jin Woo Chang

• Tumors: Jeffrey Elias

PEGASUS C

Breakfast Seminar II: Pedunculopontine Neucleus: A Real Target?

Moderators: Paolo Mazzone/Ludvic Zrinzo

• Where is the PPN: Tipu Aziz

• Clinical Results: Terry Coyne

• A Skeptical Note: Feridun Acar

APOLLON

Breakfast Seminar III: Clinical Trials in Functional Neurosurgery

Moderators: Alexander Green/Antonio DeSalles

• Movement disorders: Angelo Franzini

• Psychiatric Neurosurgery: Keith Matthews

• Surgery for Memory Enhancement: Andres Lozano

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PEGASUS AB1Plenary Session I: Emerging Technologies

8:30 ‑ 9:00 AM Presidential AddressTakaomi Taira

9:00 ‑ 9:10 AM In Memoriam: Prof. Fritz MundingerJoachim Krauss

9:10 ‑ 9:30 AM Keynote Address: From Lesioning to DBS and BeyondAndres Lozano

9:30 ‑ 10:30 AM Papers(4 papers ‑ 8 minute presentations ‑ 5 minute discussions)Moderators: Joachim Krauss/Michael Schulder

9:30‑9:43: MR-guided Focused Ultrasound Thalamotomy for Essential Tremor - one year results (309) W. Jeff Elias

9:45‑9:58: Stereotactic Implantation of Cells Secreting Nerve Growth Factor (NGF) in the Basal Forebrain of Alzheimer Patients: Update With Improved Cell Line (281) Bengt Linderoth

10:00‑10:13: Optical Imaging of Inter-areal Connectivity Evoked by Electrical Stimulation in Somatosensory and Motor Cortices (410) Katherine Kudyba

10:15‑10:28: Implanted Brain Computer Interface as a Neurofeedback System for Neurorehabilitation (204) Vincent Roualdes

10:30 ‑ 10:50 AM Refreshment Break - View Posters & Exhibits - MEETING ROOM FOYER

Tuesday, May 28, 2013

Noon ‑ 1:30 PM

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Bento Box Debate I: The Future of Ablative Neurosurgery

Moderators: Erica Petersen/ Vladimir Shabalov

• SRS: Christer Lindquist

• HIFU: Jin Woo Chang

• LITT: Michael Schulder

PEGASUS C

Bento Box Debate II: Surgery for Depression: Which Site?

Moderators: Brian Kopell/ Paresh Doshi

• Area 25: Clement Hamani

• Nucleus Accumbens: Andre Machado

• Dorsolateral PFC: Emad Eskandar

APOLLON

Bento Box Debate III: Stimulation for Epilepsy: Which Site?

Moderators: David Roberts/ Stephan Chabardes

• Hippocampus: Francisco Velasco

• Thalamic: Gordon Baltuch

• Vagus: Kensuke Kawai

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Afternoon Session I:Movement Disorders

PEGASUS C

Afternoon Session II: Epilepsy

APOLLON

Afternoon Session III:Radiosurgery

1:30 ‑ 2:00 PM Keynote Address: Lesioning, a 21st Century Treatment for Movement DisordersTakaomi Taira

Keynote Address: Epilepsy Surgery and the Mind Itzhak Fried

Keynote Adress: RadiosurgeryRecent Trends in Stereotactic Radio-surgery for Multiple Brain MetastasesMasaaki Yamamoto

2:00 ‑ 3:00 PM Papers(5 papers ‑ 7 minute presentations ‑ 3 minute discussions)

Moderators: Michael Kaplitt/ Christopher Honey

2:00‑2:10: Magnetic Resonance Guided Focused Ultrasound for Unilat-eral Thalamotomy in Medication Refractory Essential Tremor (28) Nir Lipsman

2:12‑2:22: High Frequency Stimulation at GPi Modulates GFRα1b, CAMK2A and GAD1 Gene Expression (145) Xun Kiat Ho

2:24‑2:34: Health Economics and Surgical Treatment for Parkinson’s Disease in a World Perspective (312) Gaston Schechtman

2:36‑2:46: Double-Blind Comparison of Intraoperative Subthalamic High Frequency, Low Frequency and Sham Stimulation Effects on Verbal Fluency (311) Alexander I. Troster

2:48‑2:58: Involvement of Pedunculo-pontine (PPN) and Cuneiform Nuclei (CfN) in Bipedal Locomotor Behavior: Electrophysiological Study in Normal and Parkinsonian (MPTP) Primate (291) Laurent Goetz

Papers(5 papers ‑ 7 minute presentations ‑ 3 minute discussions)

Moderators: Ashwini Sharan/Youssef Comair

2:00‑2:10: Five Hundred Stereoelec-troencephalography Procedures for Presurgical Invasive Evaluation of Drug-resistant Epilepsy: Efficiency, Safety, Application Accuracy and Outcome on Seizures (83) Francesco Cardinale

2:12‑2:22: Stimulation of the Anterior Nucleus of the Thalamus for Epilepsy (SANTE) Trial: Results Related to Region of Onset and Prior Surgical Treatments (237) Robert E. Gross

2:24‑2:34: Improved Seizure Outcomes in Resections Involving the Orbito-frontal Cortex: Evidence for “Orbito-frontal-plus” Epilepsy (91) Demitre Serletis

2:36‑2:46: Results of Surgery for Refractory Epilepsy: Highlights From a Series of 1696 Patients Submitted To Surgery (102) Arthur Cukiert

2:48‑2:58: Electrocorticographic Evidence of Different Physiopatho-logic Types in Mesial Temporal Epilepsy. Surgical Implications (139) Cristina V. Torres

Papers(5 papers ‑ 7 minute presentations ‑ 3 minute discussions)

Moderators: Larry Chin/Toru Serizawa

2:00‑2:10: Clinician Preferences in Management of Trigeminal Neuralgia - A survey of Australian Neuro-surgeons and Neurologists (164) Benjamin P. Jonker

2:12‑2:22: A New Grading System Focusing on Functional Preservation for Brain Metastasis Patients Treated With Stereotactic Radiosurgery (35) Toru Serizawa

2:24‑2:34: Time Delayed Contrast Enhanced MRI Improves Detection of Brain Metastases (352) Michael Schulder

2:36‑2:46: Delayed Contrast Extrava-sation MRI Differentiates Metastatic Tumor Progression from Radiation Necrosis after Radiosurgery (172) Roberto Spiegelmann

2:48‑2:58 Long Term Result of Gamma Knife Treatment for Prolactinomas (73) Peng Li

3:00 ‑ 3:30 PM Refreshment Break - View Posters & Exhibits - Meeting Room Foyer

10:50 ‑ 11:50 AM Papers(4 papers ‑ 8 minute presentations ‑ 5 minute discussions)

Moderators: Jeffrey Arle/Max Mehdorn

10:50‑11:03: Progress in Bionic Vision Devices (19) Jeffrey Rosenfeld

11:05‑11:18: Stereotactic Laser Ablation of Epileptic Foci: A Novel, Minimally Invasive Technique for Intractable Epilepsy (333) Jon T. Willie

11:20‑11:33: Bone Marrow Stem Cells Intraspinal Infusion Technique as a Part of a Pilot Study in ALS (351) Pedro de la Rosa Jimenez

11:35‑11:48: New Tactics for Treatment of Sensorineural Hearing Loss (161) Jin Woo Chang

11:50 ‑ NoonSpiegel and Wycis AwardsPresented by Takaomi Taira and Joachim Krauss

wssfnWorld Society for Stereotacticand Functional NeurosurgeryTuesday, May 28, 2013

3:30 ‑ 4:30 PM PEGASUS AB1

Flash presentations

(15 papers, 3 minutes each)

Moderators: Hemmings Wu/ Fabian Piedimonte

3:30‑3:33: Saccadic modulation with Concomitant Subthalamic nucleus and Pedunculopontine nucleus-stimulation in advanced Parkinson’s disease (226) Mohammad Nausahi

3:34‑3:37: Anatomical Study of the Pedun-culopontine Nucleus in Humans: Where Is the PPN? (365) Takashi Kawasaki

3:38‑3:41: Dorsal Versus Ventral Stn Stimulation Effects on the Inhibition of Action Impulses (415) Nelleke van Wouwe

3:42‑3:45: Can Low Frequency Stimula-tion At Subthalamic Area Improve the Motor Performance of Patients With Parkinson’s Disease? (163) Chiung Chu Chen

3:47‑3:50: Validation of the Electrodes’ Location by Probabilistic Tractography in Parkinson’s Disease Patients Who Underwent Bilateral Subthalamic Deep Brain Stimulation (DBS) Surgery (322) David Kis

3:51‑3:54: Different Targets for Different Patients’ Profile: how to modulate DBS for Parkinson’s Disease (347) Andrea Landi

3:55‑3:58: State Changes in Subtha-lamic Nucleus Neurons: Implications for Motor Circuits and Deep Brain Stimulation Surgery (295) Robert M. Brownstone

3:59‑4:02: Striatal-transplantation of Dopamine Neurons in Parkinson Rat Model: Subthalamic Nucleus Neuronal Activity and Gene Expression (198) Mesbah Alam

4:03‑4:06: The Role of Connectivity-based Thalamic Segmentation in the Surgical Targeting in Tremor Patients (329) Adrienn Maté

4:07‑4:10: Long Term Assessment of Functional Consequences of 150 Tibial Neurotomies for Treatment of Spastic Foot (305) Patrick Mertens

4:11‑4:14: FDG-PET Study of Cerebral Glucose Metabolic Changes After Thal-amotomy in Patients With Essential Tremor (120) Takaaki Miyagishima

4:22‑4:25: Bilateral Caudal Zona Incerta Deep Brain Stimulation for Parkinson’s Disease (85) Patric Blomstedt

4:26‑4:29: Effect of subthalamic nucleus stimulation during exercise on the mesolimbocorital dopaminergic region in Parkinson’s disease: A posi-tron Emission Tomography Study (25) Takao Nozaki

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Flash presentations

(15 papers, 3 minutes each)

Moderators: Arthur Cukiert/ Jung Kyo Lee

3:30‑3:33: Functional Connectivity Observed in Partial Epilepsy With Automotor Seizure (240) Hiroki Nishibayashi

3:34‑3:37: Posterior Cingulate Epilepsy: Clinical and Neurophysi-ological Analysis (107) Rei Enatsu

3:38‑ 3:41: Extra-temporal Resection in Refractory Epilepsy (103) Arthur Cukiert

3:42‑3:45: Efficacy of Vagal Nerve Stimulation in the Treatment of Infantile Spasms: Effects of Different Tuning and Stimulation Cycles (346) Andrea Landi

3:46‑3:49: Development of Focal Brain Cooling System for the Treat-ment of Intractable Epilepsy (348) Masami Fujii

3:50‑3:53: Intra-operative Monitoring of Inter-hemispheric EEG Connectivity During Corpus Callosotomy (100) Masaki Iwasaki

3:54‑3:57: Subtemporal Amygdalohip-pocampectomy for Medial Temporal Eplepsy. Operative Results and Neuropathological Findings (15) Tomokatsu Hori

3:58‑4:01: Risk of Epilepsy After Trau-matic Brain Injury: A Retrospective Population-based Cohort Study (16) Chien‑Chang Liao

4:02‑4:05: A Novel Electrode Array for Electrocorticography of the Temporal Pole (153) Hiroto Kawasaki

4:06‑4:09: Radiosurgery for Intrac-table Seizure Associated With Various Brain Disorders (143) Yoshihisa Kida

4:10‑4:13: Surgical Treatment Options for Adults With Lesional and Non-Lesional Epilepsies (146) Andrey R. Sitnikov

4:14‑4:17: Outcome After More Than Two Year of Temporal Lobe Epilepsy Surgery With Stereoeeg (407) Taku Ochiai

APOLLON

Flash presentations

(15 papers, 3 minutes each)

Moderators: Yoshihisa Kida/ Jean Regis

3:30‑3:33: Fractionated Stereotactic Radiosurgery for Intracranial Metas-tases: Tumor Control (304) Michael Schulder

3:34‑3:37: Magnetic Resonance Diffusion-weighted Imaging for Targeting Glioma in Stereotactic Biopsy: A Correlative Study with Histopathological Examination and Clinical Outcome (117) Yi‑Chieh Hung

3:38‑ 3:41: Radiographic Evolution of Thalamotomy Lesions Generated by Stereotactic Radiosurgery: A Two-Year Follow-up (387) Anand I. Rughani

3:42‑3:45: Interstitial Brachytherapy With Iodine-125 Seeds for Low Grade Brain Stem Gliomas in Adults: Diagnostic and Therapeutic Intervention in a One-step Procedure (193) William Ol. Contreras Lopez

3:46‑3:49: Long-term Outcomes of Gamma Knife Surgery for Classic Trigem-inal Neuralgia in Patients Younger Than 50 Years (245) Jung Kyo Lee

3:50‑3:53: A Preliminary Result of the Prospective Control Study of Gamma Knife Radiosurgery for Trigeminal Neuralgia With One Or Two Isocenters (259) Peng Li

3:54‑3:57: Gamma Knife Radiosurgery as a complementary treatment of large vestibu-laris schwannomas (255) Etienne Holl

3:58‑4:01: Staged Gamma Knife Radiosur-gery for Relatively Large Metastatic Brain Tumors (257) Atsuya Akabane

4:02‑4:05: Long Term Results of Gamma Knife Radiosurgery for Craniopharyn-gioma (341) Huai Cehe Yang

4:06‑4:09: Proposed Mechanism and Treatment Strategy for Cyst Formation and Enlargement Following Gamma Knife Surgery for Arteriovenous Malformation (148) Takashi Shuto

4:10‑4:13: Hydrocephalus following Gamma Knife Radiosurgery in the Vestib-ular Schwannoma (132) Kyoung‑Hyup Nam

(4:14‑4:17: GKS for Cervical Spinal Cord Tumors (64) Mooseong Kim

4:18‑4:21: Clinical Application of the Veri-fication Method of Leksell Gamma Plan in Multiple Metastatic Brain Tumors (162) Beong Ik Hur

4:22‑4:25: Complications of Radiosurgery for Tic in Patients With MS (334) Keith Gomes

4:26‑4:29: Validity Test of the Modified Recursive Partitioning Analysis for Brain Metastases Cases from Breast Cancer Treated Radiosurgically (178) Osamu Nagano

4:40 ‑ 5:30 PM

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Plenary Session: Scientific Highlights and Discussion, Day 1Moderators: Robert Goodman/Sun Ha PaekDiscussants: George Mandybur/Tejas Sankar

Wednesday, May 29, 2013

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PEGASUS AB1Plenary Session II: Best Science

8:30 ‑ 8:35 AM WelcomeMichael Schulder

8:35 ‑ 9:00 AMKeynote Address: The Neurophysiology of Functional NeurosurgeryYoichi Katayama

9:00 ‑ 10:35 AM Papers(6 papers ‑ 8 minute presentations ‑ 5 minute discussions)Moderators: Jin Woo Chang/Mojgan Hodaie

9:00‑9:13: Deep Brain Stimulation for Parkinson Disease - Results of the EARLYSTIM Study ( 190) Maximilian H. Mehdorn

9:15‑9:28: Treatment of Memory Decline in Alzheimer’s Disease by Deep Brain Stimulation: A Feasibility Study (71) Denys Fontaine

9:30‑9:43: Pedunculopontine nucleus-stimulation in patients with Advanced Parkinson’s disease (227) Mohammad J. Nausahi

9:45‑9:58: Long Term Effects of Deep Brain Stimulation of the Medial Forebrain Bundle (slMFB DBS) for treatment resistant depression (173) Volker A. Coenen

10:00‑10:13: Deep Brain Stimulation of the Subcallosal Cingulate Area for Treatment-Refractory Anorexia Nervosa: Phase I Pilot Trial ( 27) Nir Lipsman

10:15‑10:28: A Randomized Blinded Trial of Nucleus Accumbens Ablation to Treat Opiate Dependence in Humans: Location Correlates with Outcome (270) Guodong Gao

10:35 ‑ 10:50 AM Refreshment Break - View Posters - Meeting Room Foyer

10:50 AM ‑ Noon Papers(5 papers ‑ 8 minute presentations ‑ 5 minute discussions)Moderators: Hiroki Toda/Robert Gross

10:50‑11:03: What Happened in the Lobotomized Brain?: Tractographic Analysis of Prefrontal lobotomy for Mental Illness (165) Katsushige Watanabe

11:05‑11:18: Where the Parallels Meet: Evidence of Func-tional Convergence of Basal Ganglia Circuits in Subthalamic Nucleus From Intra-operative Multichannel-microelectrode Recording (332) Erich T. Fonoff

11:20‑11:33: Experimental Comparison in Non-human Primates of Focal Tolerance Between Epidural and Subdural Implantation of a Cortical Neuroprosthesis (276) Napoleon R. Torres‑Martinez

11:35‑11:48: Nerve Fiber Composition of Posterior Subtha-lamic Area and Its Relevance for the Treatment of Parkin-son’s Disease Symptoms (77) Francisco Velasco

11:50‑12:03: Modulation of Neural Network Excitability with an Implantable Closed-Loop DBS System (321) Paul Stypulkowsi

Wednesday, May 29, 20137:00 AM Continental Breakfast in Meeting Rooms

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Breakfast Seminar IV: Restorative Neurosurgery

Moderators: Wade Yang/Jeff Cozzens

• Gene Therapy: Michael Kaplitt • Stem cells: Roy Bakay • Transplantation: Jocelyn Bloch

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Breakfast Seminar V: Functional Stereotactic Radiosurgery

Moderators: Yoshihisa Kida/Joseph Neimat

• Movement Disorders: Larry Chin • Psychiatric Disorders: Rees Cosgrove • Pain: Motohiro Hayashi

APOLLON

Breakfast Seminar VI: Surgical Treat-ment of Head and Facial PainModerators: Tomokatsu Hori/ Manoel Teixeira

• Cluster Headaches: Denys Fontaine

• Occipital Nerve Stimulation: Oren Sagher

• Advanced Imaging in Trigeminal Neuralgia: Mojgan Hodaie

wssfnWorld Society for Stereotacticand Functional NeurosurgeryWednesday, May 29, 2013

Noon ‑ 1:30 PM

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Bento Box Debate IV: Dystonia: DBS vs. Lesioning vs. Peripheral Procedures

Moderators: Elena Moro/Claudio Pollo

• DBS is Best: Ron Alterman

• Lesioning is Best: Takaomi Taira

• Peripheral is Best: Tommy Bergenheim

PEGASUS C

Bento Box Debate V: Tourette’s Syndrome

Moderators: Ashwin Viswanathan/ Zelma Kiss

• GPi: Philippe Cornu

• Thalamus: Joachim Krauss

• GPe: Osvaldo Vilela

APOLLON

Bento Box Debate VI: Controversies in Psychiatric Neurosurgery

Moderators: Marwan Hariz/ Sally Rothemeyer

• Surgery for Schizophrenia: Bomin Sun

• Surgery for Aggression: Fabian Piedimonte

• Not So Fast: Volker Coenen

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Afternoon Session IV: From the Laboratory to the Clinic

PEGASUS C

Afternoon Session V: Surgery for Pain: Only When Nothing Else Works?

APOLLON

Afternoon Session VI: Stereotactic Technology

1:30 ‑ 2:00 PMKeynote Address: The Hyperdirect Pathway and Motor ControlAtsushi Nambu

Keynote Address: Peripheral Nerve Stimulation for PainKonstantin Slavin

Keynote Address: Stereotactic Princi-ples: The Evolution of Image GuidanceDavid Roberts

2:00 ‑ 3:00 PM Papers

(5 papers ‑ 7 minute presentations ‑ 3 minute discussions)

Moderators: Zvi Israel/Moon Chan Kim

2:00‑2:10: in Vivo Brain Repair? Elec-trical Fields Attract Newborn Brain Cells (380) Ali Jahanshahi

2:12‑2:22: Deep Brain Stimulation of the Cm-pf in Rats Alleviate Breeding-induced Deficient Prepulse Inhibition (202) Mesbah Alam

2:24‑2:34: Theta Burst Stimulation of the Hippocampus Via an Electrode Implanted in the Fornix Is Associated With Improved Cognitive Performance After Moderate Traumatic Brain Injury (58) Jonathan Miller

2:36‑2:46: Recordings of Local Field Potentials in the Bed Nucleus of the Stria Terminalis in a Rat Model of Obsessive-Compulsive Disorder (317) Hemmings Wu

2:48‑2:58: STN ‑Deep Brain Stimula-tion in OCD: Preliminary Results of the Grenoble Cohort At 18 Months Follow Up (217) Stephan Chabardes

Papers

(5 papers ‑ 7 minute presentations ‑ 3 minute discussions)

Moderators: Juan Barcia/Bengt Linderoth

2:00‑2:10: Motor Cortex Stimulation Efficacy in Refractory Neuropathic Pain Might Be Predicted by Brain 11C-diprenorphine Pet-scans (289) Patrick Mertens

2:12‑2:22: Simultaneous Trial of Deep Brain Stimulation (DBS) and Motor Cortex Stimulation (MCS) for Chronic, Intractable Neuropathic Pain (67) Byung‑chui Son

2:24‑2:34: Differential Efficacy of Motor Cortex Stimulation and Lesioning of the Dorsal Root Entry Zone for Continuous Vs Paroxysmal Pain Afterroot Avulsion (234) Youichi Saitoh

2:36‑2:46: Deep Brain Stimulation in Chronic Cluster Headache (CCH): Lead Location, Clinical Response and Neuronal Signatures (211) Fahid T. Rasul

2:48‑2:58: Rechargeable Occipital Nerve Stimulator Systems a Patient Satisfac-tion Study (144) Sara Sciacca

Papers

(5 papers ‑ 7 minute presentations ‑ 3 minute discussions)

Moderators: Rick Schuurman/ Masahito Kobayashi

2:00‑2:10: Steering Deep Brain stimula-tion: an exploratory study with a new 32-contact lead (343) Rick Schuurman

2:12‑2:22: Convection Enhanced Delivery: Infusion characteristics in ex vivo and in vivo non-human primate brain tissue (412) Gurwattan S. Miranpuri

2:24‑2:34: Accuracy of Electrode Place-ment, Clinical Response and Compli-cation rate in Frameless Stereotaxis (NexFrame) for Movement disorders (253) Matthew G. Stovell

2:36‑2:46: Validating Diffusion Tensor Imaging of the Thalamus with Intraop-erative Mircroelectrode Recording (390) Hiroki Toda

2:48‑2:58: Techniques for Axiem™ Electro-magnetic Navigation Guided Balloon Compression of Trigeminal Nerve (32) Sarah L. Olson

Wednesday, May 29, 2013

3:00 ‑ 3:30 PM Refreshment Break - View Posters & Exhibits - Meeting Room Foyer

3:30 ‑ 4:30 PM PEGASUS AB1

Flash presentations(15 papers, 3 minutes each)

Moderators: Jules Nazzaro/Jorge Guridi

3:34‑3:37: Influence on Synaptic Plas-ticity in Corticostriatal Pathway of Parkinson Disease Animal Model (377) Yuan‑Hao Chen

3:38‑3:41: Autologous Peripheral Nerve Grafts into the SN of Subjects with PD Undergoing DBS (284) Craig G. van Horne

3:42‑3:45: Cortical Electric Stimula-tion in the Treatment Brain Tumors: Induction of Plastic Changes to Obtain Extended Resection in Gliomas (184) Juan Barcia

3:46‑3:49: Bilateral Pedunculopontine Nucleus Stimulation for Progressive Supranuclear Palsy (44) Paresh K. Doshi

3:50‑3:53: Potential Role of L-PGDS as a Surrogate Marker of Frontal Lobe Dysfuntion (47) Namiko Nishida

3:54‑3:57: Subthalamic Nucleus Stimu-lation Reverses Spinal Motoneurone Activity in Parkinsonian Patients (59) Sylvie Raoul

3:58‑4:01: Different Performance Between Food Reaching Motors and Finger Precise Motors Ameliorated by STN-DBS in MPTP-treated Monkeys (118) Tetsuya Asakawa

4:02‑4:05: Isolation and Transplanta-tion Protocol of Human Fetal Neural Progenitor Cells in the Treatment of Huntington’s and Parkinson’s Disease (200) William O. Contreras Lopez

4:06‑4:09: A Novel Intraoperative Method for Monitoring Hyperacute Changes in Cerebral Ischemia (361) Hiroshi Fujioka

4:10‑4:13: Neurophysiological Char-acteristics of Subthalamic Neurons Receiving Inputs From the Limbic Cortex (376) Sumito Sato

4:14‑4:17: Anatomic Study of Fiber Tracts Linking the Basal Ganglia and Cerebellum in Patients with Parkin-son’s Disease (49) Jennifer A. Sweet

4:18‑4:21: Robot-assisted Guide Tube Implantation for Functional Neurosur-gery - Analysis of Targeting Accuracy and Procedural Time (116) Neil Barua

PEGASUS C

Flash presentations(15 papers, 3 minutes each)

Moderators: Brian Brophy/Miroslav Galanda

3:30‑3:33: Stereotactic Thalamic Vim-vcpc Stimulation for the Treatment of Cases with Central Post-stroke Pain (70) Masafumi HIrato

3:34‑3:37: Testing the Opioidergic Hypothesis of PAG-DBS for Pain: A [11c] Diprenorphine PET Imaging Study (48) Hugh P. Sims‑Williams

3:38‑ 3:41: Deep brain stimulation in Short Lasting Unilateral Headache with Conjunctival Injection and Tearing (SUNCT) (181) Sarah Miller

3:42‑3:45: Implanted Occipital Nerve Stimulation Results for Intractable Headache Predicted by Transcutaneous Electrical Nerve Stimulation (303) Vincent Roualdes

3:46‑3:49: Pulsed Radiofrequency of Sympathetic Lumbar Plexus Versus Sympathetic Block in the Management of Lower Limb Complex Regional Pain Syndrome Type 1 (324) Tiago S. Freitas

3:50‑3:53: Intrathecal Ziconotide (ITZ) for the Treatment of Sublesional Neuro-pathic Pain in Patients With Spinal Cord Lesions (296) Patrick Mertens

3:54‑3:57: Open Thoracic Cordotomy for pain: Lost art or a reviving skill? (256) Naeem A. Farooqo

3:58‑4:01: Long term Outcomes for the Use of Dorsal root entry zone (DREZ) Lesioning for Brachial Plexus Avulsion Injury (287) Jonathan R. Ellenbogen

4:02‑4:05: Motor Cortex Stimulation for the Treatment of Severe Pain (239) Vladimir A. Shabalov

4:06‑4:09: Motor Cortex Stimulation for the Treatment of Severe Pain (339) Erich T. Fonoff

4:10‑4:13: Combined fMRI, SSER, and Intraoperative Stimulation for Identifi-cation of Cortical Areas in Motor Cortex Stimulation for Pain (189) Tommy Bergenheim

4:14‑4:17: Peripheral Field Stimulation for Chronic Focal Pain (369) Milind Deogaonkar

4:18‑4:21: Selective Dorsal Rhizotomy for Neoplastic lumbosacral plexopathy in terminal pelvic cancer (40) Byung‑chul Son

APOLLON

Flash presentations(15 papers, 3 minutes each)

Moderators: M. Sam Eljamel/Wilhelm Eisner

3:30‑3:33: Definition of a Stereotactic 3D Model of the Human Insula for Neurosurgical Approach (epilepsy and Stereotaxic Surgery) (140) Afif M. Afif

3:34‑3:37: Robotics in Neurosurgical Stereotactic Interventions: Oblique Intrainsular Electrodes Implanted of Patients with Epilepsy (183) Afif M. Afif 154

3:38‑ 3:41: Comparison of Voltage and Current Driven Deep Brain Stimulation (75) Sam Eljamel

3:42‑3:45: Early Experience with MRI-directed Implantable Guide Tube Tech-nique for Deep Brain Stimulation (142) Christopher R. P. Lind

3:46‑3:49: A Novel Recessed-step Catheter for Reflux-free Convection-enhanced Drug Delivery to the Brain (111) Neil Barua

3:50‑3:53: The Yield and Safety of Robotic-assisted Stereotactic Biopsy Versus Frameless Stereotactic Biopsy (364) Tariq Aljared

3:54‑3:57: Simultaneous 32-contact Local Field Potential Recordings in the Parkin-sonian STN (344) Rick Schuurmann

3:58‑4:01: Use of a Novel, Rapidly Gener-ated Custom Platform for Stereotactic DBS Implantation (416) Jason Agran

4:02‑4:05: Identification of Blood Vessels With Micro Doppler Ultrasound Songraphy in Stereotactic Functional Neurosurgery Via Microelectrode Guide Tubes - A Prototype of High Value! (221) Wilhelm E. Eisner

4:06‑4:09: Supine Position reduces Brain Shift during Stereotactic Neuro-surgery (66) Yasushi Miyagi

4:10‑4:13: Impact of Parameters of Radiofrequency Coagulation on Volume of Stereotactic Lesion in Pallidotomy and Thalamotomy (213) Hidehiro Hirabayashi

4:14‑4:17: Neuronal Activity in the Prefrontal-cortex Is Reduced in Rats Selectively Bred for Disturbed Senso-rimotor Gating (205) Mesbah Alam

4:18‑4:21: Diagnostic Yield of 1H-MRS-supported Stereotactic Brain Biopsy: Overview of Published Results (263) Mikhail F. Chernov

4:40 ‑ 5:30 PM

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ion Plenary Session: Scientific Highlights and Discussion, Day 2

Moderators: Alon Mogilner/Ahmed Al‑KhaniDiscussants: Travis Tierney/Alexandre Francisco

7:00 ‑ 10:00 PM Gala Reception and DinnerPEGASUS

wssfnWorld Society for Stereotacticand Functional NeurosurgeryThursday, May 30, 2013

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7:15 ‑ 8:15 AM PEGASUS AB1

Breakfast Seminar VII: Setting Inter-national Standards in Functional Neurosurgery: Training, Education and Expansion

Moderators: Isao Date/Rick Schuurman

• Spectrum of Fellowships in SFN: Gaston Schechtmann

• Setting Up a Program in Functional Neurosurgery: Erich Richter

• Do We Need International Fellowship Standards? Mojgan Hodaie

PEGASUS C

Breakfast Seminar VIII: Surgery for Enhancement

Moderators: Julie Pilitsis/Guoming Luan

• Epilepsy: Eiju Watanabe

• Cognition: Emad Eskandar

• Ethical Considerations: Mark Bernstein

APOLLON

Breakfast Seminar IX: SRS: New Fron-tiers

Moderators: Masaaki Yamamoto/ Dheerendra Prasad

• Fractionation: Roberto Spiegelmann

• Microbeam Radiosurgery: Pantaleo Romanelli

• Heavy Particles: Takeshi Kondoh

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III PEGASUS AB1Plenary Session III: New Indications for Functional Neurosurgery

8:30 ‑ 8:35 AMWelcomeJoachim Krauss

8:35 ‑ 9:05 AMKeynote Address: Surgery for Neurobehavioral DisordersAli Rezai

9:05 ‑ 10:20 AM Papers(5 papers ‑ 8 minute presentations ‑ 5 minute discussions)Moderators: Aviva Abosch/Patric Blomstedt

9:05‑9:18: Deep Brain Stimulation of the Fornix and Ento-rhinal Cortex in an Experimental Model of Memory Impair-ment (379) Ali Jahanshahi

9:20‑9:33: Results of Neuromodulation of the Posterolateral Hypothalamic Region in Cluster Headache. Are We on the Right Place? (90) Fernando Seijo

9:35‑9:48: An Exploratory Pilot Study of Intra-Thecal Spinal Cord Stimulation (IT-SCS): Implications for the future management of chronic pain (206) Nandan Lad

9:50‑10:03: In Search of Neurobiological Correlates To Depression: Electrical Stimulation of the Amygdala (137) Kelly R. Bijanki

10:05‑10:18: Deep Brain Stimulation Eliminates Tic-related Neural Activity Via Interlocking With Stimulus Pulses (13) Kevin W. McCairn

10:20 ‑ 10:40 AMRefreshment Break and View PostersMeeting Room Foyer

10:40 ‑ 11:40 AM Papers(4 papers ‑ 8 minute presentations ‑ 5 minute discussions)Moderators: Giovanni Broggi/Steven Gill

10:40‑10:53: Augmentation of Perilesional Plasticity by Chronic Stimulation of the Dentatothalamocortical Pathway in an Animal Model (94) Andre Machado

10:55‑11:08: Spinal Cord Stimulation for the Treatment of Minimally Conscious State Patients (29) Takamitsu Yamamoto

11:10‑11:23: Peripheral Nerve Stimulation (PNS) and Periph-eral Nerve Field Stimulation (PNFS) for the Treatment of Chronic Neuropathic Pain (244) Emil D. Isagulyan

11:25‑11:38: Improved Intraoperative Therapeutic Window with Directional DBS Compared to Omnidirectional DBS Using a Novel Lead Design (319) Claudio Pollo

11:40 ‑ Noon WSSFN Business Meeting

Thursday, May 30, 2013

Thursday, May 30, 2013

Afternoon Session VII: WSSFN 2016: PredictionsPEGASUS AB1

3:30 ‑ 4:00 PMKeynote Address: Looking Back and Ahead in Functional Neurosurgery - Where We Came From, and Where Are We HeadingAlim Benabid

4:00 ‑ 5:00 PM Papers(4 papers ‑ 8 minute presentations ‑ 5 minute discussions)Moderators: Volker Sturm/Takeshi Kawase

4:00‑ 4:13: Anatomo-radiologic Correla-tion To Achieve Maximum Accuracy in Leads Implantation for Chronic Stimu-lation of Sphenopalatine Ganglion (215) Fabian C. Piedimonte

4:15‑4:28: Deep Brain Stimulation Induces Changes in Cerebral Perfusion in Patients With Tourett e Syndrome (210) Goetz Lutjens

4:30‑ 4:43: Localisation of the Subthalamic Nucleus in Parkinson’s Disease with Neural Beta and Gamma Activity of Local Field Potentials (345) Rick Schuurmann

4:45‑ 4:58: Deep Brain Stimulation for the Early Treatment of the Minimal Coscious Sate and Vegetative State (201) Darko Chudy

5:00 ‑ 5:30 PM Closing CeremonyResident Awards

Noon ‑ 1:30 PM

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Bento Box Debate VII: New Indications: When to Push the Limits

Moderators: Damianos Sakas/Ben Jonker

• DBS for Obesity: Donald Whiting

• DBS for Tinnitus: Paul Larson

• Not So Fast: Roy Bakay

PEGASUS C

Bento Box Debate VIII: Surgical Treat-ment of Spasticity (sponsored)

Moderators: Marc Sindou/Karl Sillay

• Dorsal Rhizotomy: Graham Fieggen

• Intrathecal Infusion: Takaomi Taira

• Neurotomy: Phillipe Decq

APOLLON

Bento Box Debate IX: Hypothalamic Tumors - What Is the Best Treatment?

Moderators: Mikhail Chernov/Ashwin Viswanathan

• SRS: Jean Regis

• Resection: Jeffrey Rosenfeld

• LITT: Taku Ochiai

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Afternoon Session VII: Psychiatric Surgery

APOLLON

Afternoon Session VIII: Imaging for Functional Neurosurgery

PEGASUS C

Afternoon Session IX: Movement Disorders

1:30 ‑ 2:00 PMKeynote Address: Guidelines for Psychiatric NeurosurgeryBart Nuttin

Keynote Address: Imaging for Epilepsy SurgeryNobukazu Nakasato

Keynote Adress: Ethics of Deep Brain Stimulation SurgeryMarwan Hariz

2:00 ‑ 3:00 PM Papers(5 papers ‑ 7 minute presentations ‑ 3 minute discussions)

Moderators: Rees Cosgrove/ Yoichi Katayama

2:00‑2:10: Neurosurgery for Psychiatric Disorders in the People’s Republic of China- Responsibilities of International Societies (293) Hemmings C. Wu

2:12‑2:22: Long-term Follow-up of Deep Brain Stimulation for Refractory Obsessive-compulsive Disorder (160) Young Cheol Na

2:24‑2:34: Deep Brain Stimulation for Severe Treatment-resistant Depression (26) Rodrigo Rodriguez

2:36‑2:46: DBS in Tourette Syndrome: Lessons Learnt After 8 Years (286) Domenico Servello

2:48‑2:58: The Vancouver Experience with Neurosurgery for Depression: Lesions versus DBS (325) Chris Honey

Papers(5 papers ‑ 7 minute presentations ‑ 3 minute discussions)

Moderators: Kostantinos Fountas/ Wai Hoe Ng

2:00‑2:10: Exploring the Anatomical Connectivity of the Human Peduncu-lopontine Nucleus With Structural and Diffusion-tensor MRI (8) Yasir Chowdhury

2:12‑2:22: White Matter Tracts Deep To Cg25: What Are We Targeting? (373) Kartik D. Bhatia

2:24‑2:34: Early Experience of Pre- and Post-contrast 7.0T MRI in Brain Tumors (267) Jae Ha Hwang

2:36‑2:46: Localization of DBS Targets by Deterministic Tractography: A Straightforward Method with Plausible Results (224) Josue Avecillas

Papers(5 papers ‑ 7 minute presentations ‑ 3 minute discussions)

Moderators: Milind Deogaonkar/ Goetz Lutjens

2:00‑2:10: Deep Brain Stimulation of the Dentato-rubro-thalamic Tract (drt) for the Treatment of Therapy Refractory Tremor (171) Volker A. Coenen

2:12‑2:22: Zona Incerta as a Target for DBS - The Umeå Experience of 100 Patients (87) Patric Blomstedt

2:24‑2:34: Anatomo-clinical Correla-tions of Deep Brain Stimulation (DBS) of the Pedunculopontine Nucleus Area (PPNa) At 12 Months Follow Up (280) Laurent Goetz

2:36‑2:46: Beta Oscillatory Activity of Single Neurons in the Subthalamic Nucleus in Patients With Parkinson’s Disease (95) Kazutaka Kobayashi

3:00 ‑ 3:30 PM Refreshment Break - View Posters & Exhibits - Meeting Room Foyer

wssfnWorld Society for Stereotacticand Functional NeurosurgeryWSSFN Sponsor and Exhibitor Information

SAKURA LEVEL

At Medtronic, we’re committed to Innovating for life by pushing the boundaries of medical technology and changing the way the world treats chronic disease. Last fiscal year, more than eight million patients benefited from our products and therapies. Medtronic DBS Therapy has been used in more than 100,000 patients worldwide for the treatment of Parkinson’s disease, essential tremor and dystonia.

Elekta is a human care company pioneering significant innovations and clinical solutions for treating cancer and brain disorders. The company develops sophisti‑cated, state‑of‑the‑art tools and treatment planning systems for radiation therapy, radiosurgery and brachytherapy, as well as workflow enhancing software systems across the spectrum of cancer care. Stretching the boundaries of science and tech‑nology, providing intelligent and resource‑efficient solutions that offer confidence to both healthcare providers and patients, Elekta aims to improve, prolong and even save patient lives.

Today, Elekta solutions in oncology and neurosurgery are used in over 6,000 hospi‑tals worldwide. Elekta employs around 3,400 employees globally and the corporate headquarters is located in Stockholm, Sweden. Website: www.elekta.com.

Committed to Advancing Neural microTargeting Worldwide

For over 40 years FHC has served the neuroscience community with a commitment to innovate through collaboration. Come see our new Cable Management System and our improved STarFix™ Platform for patient‑specific stereotaxy. Demo our WayPoint™ Navigator Planning System, the Guideline 4000 LP+™ Recording/Stimulating System and STar™ Microdrive Systems. All backed with 24x7 technical support.

Renishaw is applying cutting‑edge precision engineering technology to the chal‑lenges of functional neurosurgery. We are helping leading clinicians to enhance the safety and cost‑effectiveness of their procedures, improving patient outcomes through consistently accurate delivery of implantable devices.

The neuromate® stereotactic robot provides a platform solution for a broad range of functional neurosurgical procedures.

neuromate® has been used in thousands of electrode implantation procedures for Deep Brain Stimulation (DBS), Stereotactic Electroencephalography (SEEG), neuro‑endoscopy, biopsy, as well as R&D applications in radiosurgery, drug delivery and Transcranial Magnetic Stimulation.

Investing in innovative products, clinical initiatives, and world‑class service, Boston Scientific is committed to leading the way in spinal cord stimulation by providing better pain relief to a broad range of patients. www.controlyourpain.com

Founded in 1999, InSightec Ltd. is a privately held innovative medical device company that has developed the breakthrough MR guided Focused Ultrasound (MRgFUS) technology and transformed it into a next generation operating room. Headquartered in Israel, the company has invested in research, development, and clinical investigations of its ExAblate system to thermally ablate tumors inside the body – incision‑less, with real‑time anatomic and thermal feedback. ExAblate is currently used to treat uterine fibroids as well as for pain palliation of bone metastases. ExAblate Neuro has been developed for transcranial, functional stereotactic applications and has received CE mark for treating essential tremor, tremor dominant Parkinson’s disease and neuropathic pain. Other applications of focused ultrasound neurosurgery are under clinical investigation. More information at www.InSightec.com

St. Jude Medical develops medical technology and services that focus on putting more control into the hands of those who treat cardiac, neurological and chronic pain patients worldwide. SJM has provided leading neurostimulation therapy innovations for 30 years. The company is dedicated to advancing the practice of medicine by reducing risk wherever possible and contributing to successful outcomes for every patient.

Innsbruck‑based MED‑EL Medical Electronics is a leading provider of hearing implant systems worldwide. The family‑owned business is one of the pioneers in the industry. The two Austrian scientists Ingeborg and Erwin Hochmair developed the world’s first microelectronic‑multichannel Cochlear‑Implant in 1977. The cochlear implant was and remains the first replacement of a human sense, the sense of hearing. In 1990 they laid the foundation for the successful growth of the company when they hired their first employees. To date, the company has grown to more than 1400 employees around the world.

Today MED‑EL offers the widest range of implantable solutions worldwide to treat various degrees of hearing loss: cochlear and middle ear implant systems, EAS (combined Electric Acoustic Stimulation) hearing implant system and auditory brainstem implants as well as the world’s first active bone conduction implant. People in about 100 countries enjoy the gift of hearing with the help of a product from MED‑EL. www.medel.com

SAKURA LEVEL

UME LEVEL

MATSU LEVEL

YANAGI LEVEL

TA’KE LEVEL

Alpha Omega has been known in the industry for more than two decades, as a global leader in the fields of Functional Neurosurgery and Neuroscience Research, offering its clients breakthrough technology, unrivalled dependability, and dedi‑cated service.

For Functional Neurosurgery, Alpha Omega offers Microelectrode recording (MER) equipment for Deep Brain Stimulation (DBS) procedures along with powerful research capabilities.

For Neuroscience Research, Alpha Omega offers variety of powerful electrical and mechanical solutions in the field of In‑Vivo extracellular recording, allowing neuro‑scientists to discover brain signals even in the resolution of a single cell activity.

Cyberonics, Inc. is the leader in device solutions for epilepsy and is committed to consistently delivering innovative and effective solutions for physicians, caregivers and people with epilepsy. Cyberonics’ VNS Therapy® is the only FDA‑approved device for the treatment of refractory epilepsy, with more than 70,000 patients implanted worldwide.

WSSFN Quadrennial Meeting 2013

Brainlab develops, manufactures and markets software‑driven medical technology, enabling access to improved, more efficient, less‑invasive patient treatments.

Core products revolve around less‑invasive image guided surgery technology, more accurate and effective radiation therapy, and integration through planning and collaboration systems that bring patient data and physicians together.

Brainlab technology currently powers treatments in the fields of neurosurgery, radiation oncology, orthopedics, ENT, CMF, spine, trauma and radiology.

Privately held since its formation in Munich, Germany in 1989, Brainlab has more than 5,000 systems installed in about 80 countries. Brainlab employs 1,120 people in 17 offices worldwide, including 290 Research & Development engineers, who form a crucial part of the product development team.

Daiichi Sankyo is a global pharmaceutical company with corporate origins in Japan. We provide innovative products and services in more than 50 countries around the world. With more than 100 years of scientific expertise, our company draws upon a rich legacy of innovation and a robust pipeline of promising new medicines to help patients.

Through the accumulated knowledge and commitment of our 30,000 employees worldwide, we create innovative new and generic medicines, and new methods of drug discovery and delivery. We share a passion for innovation, as well as compassion for the patients around the world who are in need of our medicines.

Toshiba Medical sysTeMs corporaTion

Toshiba Medical Systems Corporation is a leading worldwide provider of medical diagnostic imaging systems and comprehensive medical solutions, such as CT, X‑ray and vascular, ultrasound, nuclear medicine, and MRI systems, as well as information systems for medical institutions. Toshiba Medical Systems Corporation has been providing medical products for over 80 years. Toshiba Medical Systems Corporation is a wholly‑owned subsidiary of Toshiba. Visit Toshiba Medical Systems Corporation’s web site at http://www.toshibamedicalsystems.com

For over 80 years, Ethicon has been at the forefront of innovation to advance the practice of surgery.

Starting as a surgical suture company, we’ve grown in response to the needs of health care practitioners whose life’s work it is to safely and effectively meet the needs of patients the world over.

Integra LifeSciences, a world leader in medical devices, is dedicated to limiting uncertainty for surgeons, so they can concentrate on providing the best patient care. Integra offers a vast portfolio of implants, devices, instruments and systems used in neurosurgery and neuro critical care.

KARGER is a leading international publisher of books and journals in basic and medical sciences. During the WSSFN Congress in Tokyo we are pleased to present a wide range of publications in neurosurgery. Our journal Stereotactic and Functional Neurosurgery is the official organ of the WSSFN, ASSFN and ESSFN. Free sample copies are available at our booth. Be sure not to miss the latest publications of our book series Progress in Neurological Surgery. All publications are accessible online at www.karger.com/neurosurgery, with full‑text search of articles and many other services.

The Visualase Thermal Therapy System is an MRI‑guided, minimally invasive laser ablation system which allows for monitoring of an ablation in real‑time with screen updates every 4‑5 seconds. The system is FDA‑cleared for the ablation of soft tissue including for use in neurosurgical procedures (see www.visualaseinc.com for complete indication). More than 20 US centers have now performed >150 epileptogenic foci and >150 brain tumor ablation procedures.

RECOGNIZING ADDITIONAL COMPANIES FOR THEIR CONTRIBUTION

YANAGI LEVEL Thank you to the following companies for their generosity in providing educational grants

in support of this activity:

Alpha OmegaBrainLab

CyberonicsElektaFHC

InsightecIntegra Life

Med‑ElMedtronicRenishaw

St. Jude Medical

A sincere thank you to the following exhibitors:

Alpha OmegaBoston Scientific

BrainLabCyberonics

Daiichi‑SankyoElekta

EthiconFHC

InsightecKargerMed‑El

MedtronicNANS

RenishawSt. Jude Medical

Toshiba Medical SystemsVisualase

The North American Neuromodulation Society (NANS) is dedicated to being the premier organization representing neuromodulation. NANS promotes multidisciplinary collaboration among clinicians, scientists, engineers, and others to advance neuromodulation through education, research, innovation and advocacy. Through these efforts NANS seeks to promote and advance the highest quality patient care.

WSSFN Travel AwardsThis year, the World Society is pleased to offer a large number of travel grants to residents and fellows participating in the quadrennial meeting in Tokyo. These grants, based on scientific merit and geographical location, have been made available to facilitate attendance to the meeting and are a direct reflection of the society’s mandate of nurturing the field stereotactic and functional neurosurgery across the globe.

The society wishes to recognize and encourage strong scientific contributions to the field internationally, while promoting the field of stereotactic and functional neurosurgery in areas where it is not easily available. We are encouraged by the strong participation and interest during the WSSFN interim meeting of the society in South Africa, 2011. As a result, a number of travel awards have been made available to participants from Africa. We are confident of the fruitful outcome that accompanies increasing international participation and collaboration.

I would like to acknowledge the invaluable contributions of Dr. Joseph Neimat, Vanderbilt University, and Dr. Graham Fieggen, University of Cape Town, in the selection process of the awardees.

The travel grant awardees of the 16th quadrennial meeting of the WSSFN are as follows:

Jason Agran ‑ United StatesMawuli Ametefe ‑ GhanaPedro de la Rosa ‑ SpainAnna Gamalya ‑ RussiaDavid Kis ‑ HungaryNan Li ‑ ChinaC.C. Liao ‑ TaiwanOuerchefani Naoufel ‑ TunisiaNaomi Ochieng’ ‑ Kenya

Taopheeq Rabiu ‑ NigeriaFahid Rasul ‑ United KingdomJie Ren ‑ ChinaAnand Rughani ‑ CanadaSamuila Sanoussi ‑ NigerDemitre Serletis ‑ United StatesKrzysiek Szalecki ‑ PolandHemmings Wu ‑ Belgium

It has been a pleasure to participate in the selection of the travel awards and we welcome you all to Tokyo!

Mojgan HodaieScientific Program co‑Chair and Travel Awards Coordinator