…The Sta n d a rd for Pa rticle Coating Since 19 9 2

Wu rster HS™

In 1992 Glatt introduced the industry’s first major inno-vation in air suspension coating since the original Wurster.The Wurster HS™ achieves levels of performance andproductivity previously considered impossible, and hasbecome the “workhorse” for pharmaceutical coating andlayering. Patent No. 5,236,503

The Wurster HS™ has shown spray rates two, threeand even four times faster than conventional Wursters.This directly translates into increased productivity andlower manufacturing costs.

P A G E T W O

The Wurster HS™ is available as a full product line from a 6”lab-scaleunit through a 70” production machine . This technology can also beretrofitted to existing fluid bed processor s.

WU R S T E R HS™

FI N E PA RT I C L E

COAT I N G

PR E V E N T S

AG G L O M E R AT I O N

PRO B L E M S

HI G H SP E E D COAT I N G

Until the HS, p h a rm a c e u t i c a lm a nu f a c t u r e rs had to acceptthe potential of agglomerationon conventional Wursters dueto either high spray rates or fineparticle sizes. The Wurster HS’sunique design characteristics allbut eliminate agglomeration as aprocessing limitation.

The Glatt Wurster HS™ brokethe 100 micron barrier, allowingprecise coatings to be reliablyapplied to fine part i c l e s .C o n v e n t i o n a l Wu rs t e rscannot do this. The WursterH S™ has opened up newavenues for formulators and R&Dscientists.

Wurster HS ™

Coating Technolo gy has ne ver been t

Cutaway showing coating thickness

Coating product population,average size = 100 micron (approx)

Section showing coating integrity

Pictured above are four (4) electron microscope (SEM) images ofPharmaceutical Microgranulation with a Latex Polymer Coating

There are more Glatt Wurster coaters operating worldwidethan any other. Since we knew how important this excitingtechnology would be, we have outfitted our FDA registereddevelopment laboratory with an 7”,9”,18”& 32”Wurster HS™

for customer trials. To schedule a trial or receive information,please contact us at 201-825-8700 or visit our web site atwww.glattair.com

P A G E T H R E E

Glatt’s INPRO™ nozzle mounting system allows removalof the spray nozzles during processing without openingthe machine tower or interrupting fluidization. T h eINPRO™ system utilizes the standard high performanceHSnozzle and does not require any special tools.

INPRO™ Removable Nozzle(s)

Center Discharge

PRO C E S S LA B O R ATO RY

I N P RO ™RE M OVA B L E NO Z Z L E S

CE N T E R DI S C H A R G E

Close-up showing coating integrity,size = 100 micron (approx)

- High Speed Coat ing- Process F ine Par t i c l e s

- Avoid A g g l o m e r a t i o nn the same

This feature provides a center dischargemechanism for final product discharge atthe conclusion of a batch. Discharge is typ-ically completed in a matter of minuteswith gentle material handling.

WURSTER HS™ DATA: PRODUCTION SIZE SPECIFICATIONS

Product Volume1 (liters)

Air Volume (m3/hr)

Differential Pressure (mmWG)

Number of Nozzles

Wurster HS

102

3,000

1,200

1

417

6,000

1,200

3

820

10,000

1,200

6

1. Figures are working volume (that is it does not include volumes inside the partition).

2. Data subject to change without notice.

18” 32” 46”

1105

15,000

1,200

9

55”

2400

20,000

1200

12

70”

Glatt® GmbH Process Technology

Bühlmühle

79589 Binzen/Germany

Phone: (+49) (-7621) 6 64 0

Fax: (+49) (-7621) 6 47 23

E-mail: mail@glatt.de

Glatt® Maschinen- & Apparatebau AG

Kraftwerkstraße 6

4133 Pratteln 1/Switzerland

Phone: (+41) (-61) 8 26 47 47

Fax: (+41) (-61) 8 26 48 48

E-mail: glatt-ag@glatt-ag.ch

Glatt® Systemtechnik GmbH

Grunaer Weg 26

01277 Dresden/Germany

Phone: (+49) (-351) 25 84 0

Fax: (+49) (-351) 25 84 328

E-mail: glatt.dresden@t-online.de

Glatt® Ingenieurtechnik GmbH

Nordstraße 12

99427 Weimar/Germany

Phone: (+49) (-3643) 47 0

Fax: (+49) (-3643) 47 12 31

E-mail: git@glatt.de

Glatt® Ingenieurtechnik GmbH

Nordstraße 12

99427 Weimar/Germany

Phone: (+49) (-3643) 47 0

Fax: (+49) (-3643) 47 12 31

E-mail: git@glatt.de

Glatt® Pharmatech S.à.r.l.

Parc Technologique

6, rue Louis Néel

21000 Dijon/France

Phone: (+33) (-3) 80 74 32 64

Fax: (+33) (-3) 80 74 43 95

E-mail: glatt-pharmatech@wannadoo.f

Glatt® Protech Ltd.

Swannington Rd. Cottage Lane Ind. Est.

Broughton Astley

Leicester LE9 6TU/Great Britain

Phone: (+44) (-1455) 28 58 58

Fax: (+44) (-1455) 28 55 10

E-mail: glatt-protech@glatt-

protech.co.uk

Ad d re s s e s

Glatt® Air Techniques Inc.

20 Spear Road

Ramsey, NJ 07446 USA

Phone: (201) 825-8700

Fax: (201) 825-0389

E-mail: info@glattair.com

www.glattair.com

T h e G l a t t g r o u p

e mp l o y s o v e r

1 , 5 0 0 p e o p l e i n

2 0 e n te r p ri s e s .