zotepine for behavioural and psychological symptoms in dementia: an open-label study

1
CNS Drugs 2004; 18 (15): 1165 CORRESPONDENCE 1172-7047/04/0015-1165/$31.00/0 © 2004 Adis Data Information BV. All rights reserved. weeks, approximately 8 weeks) were not included in Zotepine for this retrospective analysis. A total of 24 patients fulfilled criteria for inclusion in the per-protocol Behavioural and analysis. Psychological Symptoms Michael K. Rainer Memory Clinic and Psychiatric Department, in Dementia: An Open- Donauspital, Sozialmedizinisches Zentrum Ost, Vienna, Austria Label Study Christine Kr ¨ uger-Rainer We would like to clarify the study design de- Memory Clinic and Psychiatric Department, scribed in our recently published paper on Donauspital, Sozialmedizinisches Zentrum Ost, zotepine. [1] Vienna, Austria To obtain data from ‘real life’ patients, we used a retrospective study design. Individual patient data Manfred Haushofer were extracted from the records of a pool of patients Memory Clinic and Psychiatric Department, who had dementia-related psychosis with behav- Donauspital, Sozialmedizinisches Zentrum Ost, ioural and psychological symptoms of dementia. Vienna, Austria These patients were treated with zotepine and were routinely visited and tested using standardised as- Hermann AM Mucke sessment tools and rating scales every month. Pa- H.M. Pharma Consultancy, Vienna, Austria tients were included in the per-protocol population if all assessments were available over a period of 2 Reference months. Patients for whom there were insufficient 1. Rainer MK, Mucke HAM, Kruger-Rainer C, et al. Zotepine for data for our outcome measures of interest at the behavioural and psychological symptoms in dementia: an defined assessment times (baseline, approximately 4 open-label study. CNS Drugs 2004; 18 (1): 49-55

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Page 1: Zotepine for Behavioural and Psychological Symptoms in Dementia: An Open-Label Study

CNS Drugs 2004; 18 (15): 1165CORRESPONDENCE 1172-7047/04/0015-1165/$31.00/0

© 2004 Adis Data Information BV. All rights reserved.

weeks, approximately 8 weeks) were not included inZotepine for this retrospective analysis. A total of 24 patientsfulfilled criteria for inclusion in the per-protocolBehavioural andanalysis.

Psychological Symptoms Michael K. RainerMemory Clinic and Psychiatric Department,in Dementia: An Open- Donauspital, Sozialmedizinisches Zentrum Ost,

Vienna, AustriaLabel Study Christine Kruger-Rainer

We would like to clarify the study design de-Memory Clinic and Psychiatric Department,

scribed in our recently published paper on Donauspital, Sozialmedizinisches Zentrum Ost,zotepine.[1]

Vienna, AustriaTo obtain data from ‘real life’ patients, we used a

retrospective study design. Individual patient data Manfred Haushoferwere extracted from the records of a pool of patients Memory Clinic and Psychiatric Department,who had dementia-related psychosis with behav- Donauspital, Sozialmedizinisches Zentrum Ost,ioural and psychological symptoms of dementia. Vienna, AustriaThese patients were treated with zotepine and wereroutinely visited and tested using standardised as- Hermann AM Muckesessment tools and rating scales every month. Pa- H.M. Pharma Consultancy, Vienna, Austriatients were included in the per-protocol population ifall assessments were available over a period of 2

Referencemonths. Patients for whom there were insufficient1. Rainer MK, Mucke HAM, Kruger-Rainer C, et al. Zotepine fordata for our outcome measures of interest at the behavioural and psychological symptoms in dementia: an

defined assessment times (baseline, approximately 4 open-label study. CNS Drugs 2004; 18 (1): 49-55