zotepine for behavioural and psychological symptoms in dementia: an open-label study
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CNS Drugs 2004; 18 (15): 1165CORRESPONDENCE 1172-7047/04/0015-1165/$31.00/0
© 2004 Adis Data Information BV. All rights reserved.
weeks, approximately 8 weeks) were not included inZotepine for this retrospective analysis. A total of 24 patientsfulfilled criteria for inclusion in the per-protocolBehavioural andanalysis.
Psychological Symptoms Michael K. RainerMemory Clinic and Psychiatric Department,in Dementia: An Open- Donauspital, Sozialmedizinisches Zentrum Ost,
Vienna, AustriaLabel Study Christine Kruger-Rainer
We would like to clarify the study design de-Memory Clinic and Psychiatric Department,
scribed in our recently published paper on Donauspital, Sozialmedizinisches Zentrum Ost,zotepine.[1]
Vienna, AustriaTo obtain data from ‘real life’ patients, we used a
retrospective study design. Individual patient data Manfred Haushoferwere extracted from the records of a pool of patients Memory Clinic and Psychiatric Department,who had dementia-related psychosis with behav- Donauspital, Sozialmedizinisches Zentrum Ost,ioural and psychological symptoms of dementia. Vienna, AustriaThese patients were treated with zotepine and wereroutinely visited and tested using standardised as- Hermann AM Muckesessment tools and rating scales every month. Pa- H.M. Pharma Consultancy, Vienna, Austriatients were included in the per-protocol population ifall assessments were available over a period of 2
Referencemonths. Patients for whom there were insufficient1. Rainer MK, Mucke HAM, Kruger-Rainer C, et al. Zotepine fordata for our outcome measures of interest at the behavioural and psychological symptoms in dementia: an
defined assessment times (baseline, approximately 4 open-label study. CNS Drugs 2004; 18 (1): 49-55