+

Genital Herpes

By: Katie Redinger

+History

Known for at least 2,000 years

Emperor Tiberious banned kissing due to cold sores

+History

“Vocational disease of women”

Not found to be a virus until the 1940s

+History

Disease became stigmatized during the 1970s

Merely a cold sore in an odd place

+What is Genital Herpes?

STD caused by Herpes Simplex Virus – Type 1 or 2

Most caused by HSV-2

+What is Genital Herpes?

Herpesviridae family

Similar to Hand, Foot and Mouth disease

+What is Genital Herpes?

Lays dormant in ganglion

Never goes away

Flare ups occur in location of exposure

+What is Genital Herpes?

Infection at one site prevents infections starting in another site. (Genital, Oral, Ocular, Whitlow)

Creates antibodies

+Structure

Double stranded DNA virus

Uses RNA polymerase II to create viral DNA

+

+Symptoms

Break outs of blisters, chancres, and tender ulcers

More serious cases affect the eye and central nervous system

+Symptoms

First outbreak usually occurs within 2 weeks of exposure

May also include flu-like symptoms

Frequency decreases overtime (4-5 within a year)

+Complications

Bell’s Palsy, facial paralysis, may be caused by HSV-1

Proposed Alzheimer's.

+Transmission

Contact with ruptured sores

Skin to skin contact

Sexual contact

+Transmission

Can occur between outbreaks

Skin may contain virus without sores (small rash)

+Transmission

HSV-2 Genital to Genital

HSV-1 Oral to Oral, Hand to Oral, Oral to Genital

+Demographics

16.2 % (1/6) Americans ages 14-49 have HSV-2

More common in women

Transmission is more common Male Female (8-10%)

+Demographics

Worldwide rate of infection 60-90%

+Prevention

Use of condoms

Abstinence

+Living with Herpes

Topical creams

Vaccines are in clinical trial

Antivirals

+Sources