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• A Glance at the Innovations • The Priz

es •

Pres

s

Voices from the Field Panel • Pitching Cha

lleng

esIn February 2016, 200 participants gathered at Massachusetts General Hospital for a hack-a-thon to change the trajectory of can-cer worldwide. Clinicians, designers, developers, and entrepreneurs joined forces to create new technologies, business models, and process innovations to transform cancer prevention, diagnosis and care in resource-limited settings. Over the course of the weekend, the innovators pitched 50+ clinical challenges, formed 20+ teams, and presented their innovations in Boston, India, and Uganda. A total of 9 awards were given to the winning teams in the form of monetary awards, acceleration support, and access to pro-totyping facilities.

Net

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king Reception • Technology Showcase •

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r Mentors • The Teams • Rem

ote Hack

The Global Cancer Innovation Hack-a-thon is made possible by the generous support of:

Generous donations provided by:

Organizers

Partners

4.1 Global Cancer Innovation Hack-a-thon

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Networking Reception

Participants, mentors, and international guests came together on Friday evening to network in advance of the hack-a-thon. The re-ception kick-started the collaboration and interdisciplinary discourse so critical to the hack-a-thon process.

Technology Showcase

During the reception, four groups presented their innovative technologies, which either related to cancer care or were designed for low- and middle-income countries. The featured innovations included:

• High-resolution optical imaging device (MIT)

• Low-cost, image-guided photodynamic therapy for oral cancer (Wellman Center for Photomedicine)

• Global Cancer Project Map, a web-based platform that catalogs international cancer research, care, and outreach programs (Global Oncology)

• Sustained-release implants for intraperitoneal drug delivery to treat peritoneal metastases (Koch Institute)

Voices from the Field Panel

Participants and mentors arrived on Saturday morning to hear Welcome Addresses and the Voices from the Field Panel discussion, where a patient discussed her experience living with cancer and veteran clinicians shared their experiences practicing in the field and identified the most critical needs. Dr. Franklin Huang, Co-Founder and Co-President of Global Oncology and Instructor at Harvard Medical School, moderated the panel. The panel included:

• Dr. Thomas (Ti) Jones (Peace Corps, Uganda)

• Dr. Santosh Gowda (Narayana Health, India)

• Dr. Sunil Bhat (Narayana Health, India)

• Dr. Joaquin Barnoya, MPH (Unidad de Cirugía Cardiovascular, Guatemala)

• Ms. Kara Olivier, RN (Mass General Hospital, USA)

• Dr. Eric Krakauer (Mass General Hospital, USA)

• Dr. Danny Milner, MPH (Mass General Hospital, USA)

• Ms. Suezanne Bruce (cancer patient, USA)

“I want quality of life, not quantity.”

- Suezanne Bruce, lymphoma survivor

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Pitching Challenges

In addition to the 13+ clinical challenges identified by the organizing team, participants pitched over 50 self-identified “pain points.” These challenges and pain points became the foundation of team formation and hacking solutions through the weekend. Some sample pitches:

• Lack of awareness of cancer and the presence of cultural stigmas limit the number of people seeking care.• Many cancer outpatients have problems with adhering to their chemotherapy treatment regimens.• Recording early signs of sepsis (fever, tachycardia) and transmitting this data to the nurse to start antibiotics for

neutropenic patients on inpatient pediatric oncology wards• Empowering women to identify their risk for cervical cancer from the privacy and comfort of their own homes

– something as simple, low-cost, and powerful as a breast self exam or a rapid pregnancy test but for cervical cancer

A Look at our Mentors

CAMTech recruited 45 multi-disciplinary mentors to support teams throughout the 48 hours of the hack-a-thon. Mentors played a vital role by sharing their expertise in health, engineering and/or business to aid in the development of new tools and technologies. Eight remote mentors dialed in from Uganda, Tanzania, three cities in Rwanda, two cities in India, and across the US to share their expertise in public health, intellectual property, mHealth, diagnostics, and more. A few of the mentors:

Sudha Sivaram Center for Global Health, National

Cancer Institute

Dr. Fidel Rubagumya Rwanda Children’s Cancer Relief

Dr. Joaquin Barnoya Unidad de Cirugía Cardiovascular

de Guatemala

Elizabeth Johanssen Design that Matters

Dr. Santosh Gowda Narayana Health

Tracy Li Janssen

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The Teams

During the weekend, 20 cross-disciplinary teams formed in Boston to co-cre-ate solutions to pressing clinical problems in LMICs.

Remote Hack

CAMTech coordinated synchronous hack-a-thons in Uganda and India during the Boston-based hack-a-thon. Participants dialed in from abroad to watch the Welcoming Remarks, Voices from the Field Panel, and Pitching via videocam and connected with the mentors assembled in Boston via Skype and email.

• Uganda Hack: 24 participants and six mentors gathered at the CAMTech Co-Creation Lab at the Mbarara University of Science and Technology to hack. During the course of the weekend, six teams formed and developed novel solutions to tackle cancer in low- and middle-income countries. The six teams presented to a panel of judges in Mbarara, and the judges picked the winning team.

• India Hack: 10 students came together at the Vellore Institute of Technology and formed three teams during the course of the weekend, and one three-member team hacked from the Lattice Innovations office in New Delhi. These teams presented their innovations via videoconference to a panel of judges in Boston, and one team was selected as the winner.

A Glance at the

Innovations

o True Blood: tool kit for starting blood donation campaign

o mNCR: a mobile-based open-source national cancer registry as a model for LMICs

o Motiba: using text messages to help patients in remote areas manage chemotherapy side-effects

o Care on the Go: a mobile treatment and diagnostic vehicle

o OralEye: using computer vision technology to quickly and cheaply screen for oral cancer

o Automated Cancer Care: a low-cost device to upload patient data records to the cloud database

o Maukhik (INDIA): cheap, portable oral screening tool that uses blue light spectroscopy to identify tumors

o Cancer Net (UGANDA): intriguing and educative designs to create awareness of breast cancer among newspaper readers and school-going

children

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The Prizes

CAMTech offered eight prizes totaling $5,500, access to the Alpha Core prototyping lab at Boston University and accelerator support from CAMTech:

$1,000 First Prize: First Prize went to Fever Finder, which is a fever finder for sepsis identification in immunocompromised pediatric chemotherapy in-patients in LMICs.

$500 Most Implementable Technology: This prize went to WishList, a website that connects NGOs, policy advocates, and volun-teer networks with global health providers on the ground to share medical supplies and trained clinicians.

$500 Most Innovative Solution: VeinGuard won this award for their device, which minimizes damage from extravasation by stop-ping the flow in a chemotherapeutic IV when flow decreases below a threshold.

$500 Best Business Model: This prize went to Team Shared Health, a patient-to-patient funded cancer screening, improving access to cancer screening and collection of data with minimal cost.

$250 Uganda Winner: Gastrointestinal Cancer Primary Prevention won first prize at the Uganda Hack for their innovation, which helps identify high-risk individuals and recommends frequency of screening accordingly or stepwise management.

$250 India Winner: The winner of the India competition was Team Alia, an oral accessory for patients with laryngeal cancer that assists with speech rehabilitation via smartphones.

Alpha Core Lab: One year of access to the Alpha Core facilities at The Center for Future Technologies in Cancer Care (CFTCC), in-cluding access to prototyping equipment and the available resources of CFTCC. CFTCC focuses on the identification, prototyping and early clinical assessment of innovative point-of-care technologies for the treatment, screening, diagnosis and monitoring of cancers. This award went to three teams:

1. Creative Cancer Explanations: online platform that connects clinicians to creative content to build patient trust, improve adherence to treatment, and increase survival rates.

2. Fever Finders: sepsis identification in immunocompromised pediatric chemotherapy in-patients in LMICs3. Smart Clot: point-of-care device to measure blood coagulability

CAMTech Accelerator Support: In addition to the existing expertise and resources provided through the CAMTech Innovation Plat-form, each winning team will receive tailored mentorship and support to accelerate the path to commercialization.

$2,500 Post-Hack Prize: This prize goes to the team that makes the most progress on their innovation during the 60 days after the event. Thirteen teams submitted applications for the Midpoint Evaluation, and the final selection process is ongoing.

Press Highlights

Fever Finder Names Winner of Global Cancer Innovation Hack-a-thon at MGH https://medtechboston.medstro.com/blog/2016/03/01/fever-finder-named-winner-of-the-global-cancer-innovation-hackathon-at-mgh/

Press Release http://www.massgeneralcenterforglobalhealth.org/camtech/wp-content/uploads/2016/03/Global-Cancer-Innovation-Hack-a-thon-Post-Hack-Release.pdf