10. unit 2 respiratory system

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    Unit 2A

    Human Form & Function

    Body systems

    The respiratory system

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    Further information

    Further information aboutthis topic can be found inOur Human Species

    (3rd edtn)

    Chapter 11, sections 1-2,4-6

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    Background reading

    Our Human Species (3rd edtn.)

    Chapter 11, Gas Exchange

    Sections 1, 2, 4, 5, 6, 7

    Student work book

    Topic 9, Respiratory system

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    The respiratory system

    Structure

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    Organs of the respiratory system

    Larynx

    TracheaRib cage

    Bronchus

    Mediastinum

    Lung

    Diaphragm

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    Section through the head

    Nasal cavity

    Palate

    Tongue

    Pharynx

    Hyoid bone

    Epiglottis

    Larynx

    Esophagus

    Teeth

    Vocal cords

    The Miles Kelly Art library, Wellcome Images

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    The mucous lining

    The nasal cavity and upper airwayshave amucous lining.

    The epithelial lining containsgoblet

    cellswhich secrete a clear, stickymucus.

    The function of mucus is to trap dirt

    particles and microbes before theyenter the lungs.

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    The nose (nasal cavity)

    Air enters and leaves the bodythrough the nose.

    Here it is cleaned, warmed andmoistened before entering thebody.

    The nasal secretions contain ananti-bacterial enzymelysozyme.

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    A section through the nasal cavity

    The Miles Kelly Art library, Wellcome Images

    Nostril

    Hard palateSoft palate

    Sinus

    NASALCAVITY

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    The larynx (Adams apple or voice box)

    The larynx is a box-likestructure constructedfrom nine cartilagesand is the entrance to

    the trachea and lungs. The larynx houses the

    vocal folds orvocal

    cords. The entrance to thelarynx is protected bytheepiglottis.

    Grays Anatomy

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    The bronchial tree

    Larynx

    Trachea

    Bronchus

    Bronchiole

    The Sourcebook of Medical Illustration (The Parthenon Publishing Group, P. Cull, ed., 1989)

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    Trachea & bronchi

    The trachea & bronchi are

    reinforced with C-shaped rings ofcartilage (these prevent the tubescollapsing during inhalation).

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    The bronchi

    The Miles Kelly Art library, Wellcome Images

    Mucouslining

    Muscular

    wall

    Cartilagerings

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    The upper airways are linedwith a ciliated mucous

    membraneThe sticky mucus traps dirt &microbes

    The cilia sweep the dirty mucusup the trachea and into thethroat.

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    The ciliated lining tissue

    Mucus-secretinggoblet cells

    Cilia

    G. Meyer, ANHB-UWA,

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    EM of ciliated epithelium & goblet cells

    D Gregory & D Marshall, Wellcome Images

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    Alveoli

    The brochioles terminate in microscopicclusters of air sacs thealveoli.

    Gas exchange takes place in the alveoli.

    AlveoliG. Meyer, ANHB-UWA

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    The alveoli (air sacs)

    The Miles Kelly Art library, Wellcome Images

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    Section through a lung showing alveoliand blood supply

    M I Walker, Wellcome Images

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    The respiratory system

    Gasexchange

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    Exchange surfaces

    Like all exchange surfaces, thealveoli:

    are very thinhave a large surface area

    are moisthave a rich blood supply

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    Breathing

    Breathing (sometimes referred toasventilation) is the process ofmoving air into and out of thelungs.

    The purpose of breathing is to

    exchangeoxygenandcarbondioxidebetween the lungs andthe air .

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    Boyle's law

    Boyle's law states that: for a fixed amountof gas kept at a fixed temperature,pressure (P)and volume (V)are inversely

    proportional (while one increases, theother decreases).

    This can be stated mathematically as:PV = k

    where: Pis thepressure, Vis thevolume&kis a constant value representative ofthe pressure and volume of the system.

    http://en.wikipedia.org/wiki/Pressurehttp://en.wikipedia.org/wiki/Volumehttp://en.wikipedia.org/wiki/Volumehttp://en.wikipedia.org/wiki/Pressure
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    Respiration

    Respiration is the transport ofoxygen from the air to the

    tissues and the transport ofcarbon dioxide in the oppositedirection.

    [not to be confused with the process ofcellular respiration discussed earlier]

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    External respiration andInternal respiration

    External respirationis themovement of O

    2

    and CO2

    betweenthe lungs and the bloodstream.

    Internal respirationis the

    exchange of O2 and CO2 betweenthe blood and the tissues.

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    External respiration

    Partial pressure (mmHg)

    Alveolar air Deoxygenatedblood

    Oxygenatedblood

    Oxygen 100 40 100

    Carbon

    Dioxide

    40 44 40

    Breathing maintains the correct

    concentration of gases in the lungs

    Concentration

    gradient

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    Breathing inhaling(remember P1V1 = P2V2)

    Anatomicalchanges

    V P1 P1:P2 Result

    Rib cageraised

    Diaphragm

    flattens

    Increases Decreases P1

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    Thoracic volume

    Rib cage relaxesDiaphragm domed

    Rib cage raisedDiaphragm flattens

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    P1V1 = P2V2

    A bicycle pump worksin much the same way

    as the lungs

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    The lungs work in much the sameway as a bicycle pump

    If you increase the volume of thechamber air is sucked in

    If you decrease the volume of thechamber air is forced out

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    Breathing exhaling(remember P1V1 = P2V2)

    Anatomicalchanges

    V P1 P1:P2 Result

    Rib cagerelaxes

    Diaphragmdomed

    Decreases Increases P1>P2 Air forcedout oflungs

    V = volume of thoracic cavity

    P1 = pressure in thoracic cavity

    P2 = air pressure

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    The Miles Kelly Art library, Wellcome Images

    INHALE EXHALE

    Ribcageraised

    Ribcagelowered

    Diaphragm

    domed

    Diaphragmflattened

    Thoracic volume

    increasedThoracic pressure< air pressure

    Thoracic volume

    decreasedThoracic pressure> air pressure

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    Why breathe?

    Fresh air passingthrough the lungsdelivers oxygen to thered blood cells. At the

    same time, wastecarbon dioxide isremoved from theblood.This can only occur iffresh air is constantlycirculating through thelungs.

    Wellcome Photo Library

    Carbondioxide

    Oxygen

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    Oxygen transport

    Oxygen combines withhaemoglobininRBCs to formoxyhaemoglobin.

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    Carbon dioxide transport

    Most CO2 is transported in the plasmaas dissolvedbicarbonate ions.-

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    Oxygen saturation

    http://pharyngula.org/~pzmyers/MyersLab/teaching/Bi104/l07/bohr.html
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    Diseased lung tissue

    Photo by Pll

    CDC

    A. healthy lung tissue

    B. Smokers lung

    C. Emphysema

    A

    B

    C

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    Study Guide

    Read:

    Our Human Species

    Chapter 11, sections 1-2, 4-6

    Complete:

    Workbook

    Topic 9, Respiratory system