1,000,000,000 7,000,874 6587 423 8 1 us $ investment hours of work experiments researchers years...
Post on 18-Dec-2015
222 views
TRANSCRIPT
1,000,000,0007,000,874
6587423
81
US $ investmenthours of workexperimentsresearchersyearsdrug
Pharma is experience challenges
Pharma R&D is adapting for the future
Focus is on:
•Productivity, ROI
•Externalization & Collaboration
•Diversification
•Personalized Medicine
We want to contribute
• Dedicated Science, Medical Information company• 7,000 Employees• PhD scientists, information
scientists, publishers
• Extensive scientific network• 600,000 authors• 300,000 reviewers• 70,000 journal editors and
board members
• Publish• 300,000 articles/yr• 2,000 journals• 20,000 books• Leading titles (e.g. Cell, The
Lancet)
• Global STM coverage• 18,000 titles used in
abstracting, indexing• Extensive patent coverage
(USTPO, EPO, WPO)
Our information spans Pharma’s value chain
TargetValidation
Lead ID
LeadValidation PoCPhase
IPhaseII
PhaseIII
PhaseIVToxicity Safety Post
LaunchTargetFinding
Trusted External R&D
Evolving with Pharma R&D
I. Identify relevant knowledge that drives R&D
II. Disseminate content to scientists, R&D decision makers
III. Make content interactive and actionable
Creating Insight
Identify relevant content that drives R&D
... the past... the present
... the past
Disseminate Content to Scientists, R&D decision makers
... the present
... The past
Make Content Interactive and Actionable
... The present
Why is Elsevier here?
Novartis announces USD 1 billion investment to build largest pharmaceutical R&D institute in China Press Release November 2009
Because our customers have come here....
... And our new customers are here
What is Reaxys?
A workflow solution for researchers in chemistry, drug discovery and related scientific areas
Using Reaxys researchers can
• Easily access validated reaction and substance data, ranking and filtering for relevant results
• Source available chemicals• Plan and optimize synthetic route• Export and share results for immediate action in the lab
An extensive repository of reaction and substance property data, Reaxys includes:
• Organic, inorganic, organometallic chemistry from 400 journals
• Coverage from 1771 - present• World Patent Office, European Patent Office and US English
language patents from the major chemistry patent classes
Reaxys extracts valuable chemical properties and reaction details from journals and patents.
1H NMR
300 MHZ
Five good reasons to use Reaxys
1. The wealth of experimentally validated data which can be searched, filtered and ranked to find the most relevant answer to a specific question quickly.
2. Functionality beyond data searching: synthesis planner, results management, smart analysis tools for fast evaluation.
3. No user or usage limits: flat-rate for institution-wide access at any time.
4. The intuitive interface and online educational material help reduce your training efforts.
5. Interoperable: linking to SciVerse Scopus, full-texts at publishers and patent offices. Access to your own library settings via OpenURL resolver is possible.
Professor Peter Johnson, University of Leeds
What our customers say:
Peter Johnson, University of Leeds
Reaxys is used by 24 of the Top-25* ranked academic chemistry research programs
Src: 2011 www.arwu.org
Reaxys Case Study:
Finding coumarin glycosides
What we will do
• Search by structure
• Filter By substructure, spectra, and bioactivity
• Export to a spreadsheet
• Create a Synthesis Plan
• Use the Form-based and Advanced Search Tabs
• Search by Keyword
17
HO
O
Examples:Isolate the substances that
have NMR data and antibacterial activity
Find coumarin glycosides
O
O
O
O
O
O
coumarin
glucopyranose
5
*bac*
antibacbacterio
catalyst
*’
palladium
Reaction type
hydrogenation
Coumarin NEXT glycosideC*marin* NEXT glycosid*
What you have seen
• Search by structure
• Filter By substructure, spectra, and bioactivity
• Export to a spreadsheet
• Create a Synthesis Plan
• Use the Form-based and Advanced Search Tabs
• Search by Keyword
47
Thank You
• Reaxys training materials can be found at www.reaxys.com/info
• Contact Reaxys Customer Support at: [email protected] if you would like to schedule a Reaxys Advanced Training webinar
Thank you
• Questions?