101-9118340612010923-biotech lifesciences catalogue 20102011
TRANSCRIPT
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Biotechnology
Life Sciences
Biotechnology / Life Sciences Department
General laboratory Bioprocessing
Bioengineering Genetics Chemistry
Product Catalog 2010-2011
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Biosafety cabinets (Laminar Flow)
Centrifuges
Laboratory freezers
Freeze Drying
Content
GENERAL LABORATORYGENERAL LABORATORYGENERAL LABORATORYGENERAL LABORATORY
BIOBIOBIOBIO ENGINEERINGENGINEERINGENGINEERINGENGINEERING
GENETICSGENETICSGENETICSGENETICS
CHEMISTRYCHEMISTRYCHEMISTRYCHEMISTRY
CO2 incubators
Circulators, Open Water baths and Cryo baths
Bioreactors
Laboratory ovens
Shakers
Thermal cyclers (PCR)
Polarimetry
Refractometry
3
7
14
14
9
10
8
11-13
9
4-5
6
Page
8
Gel electrophoresis Systems 7
BIOPROCESSINGBIOPROCESSINGBIOPROCESSINGBIOPROCESSING
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General Laboratory
Laboratory cooling
UPUL SERIESUpright ULT Freezer
Single compressor Low energy consumption Low noise level 100% HCFC/CFC free Low Heat dissipation Inner doors Castors and door key lock Stainless steel interior &Stainless steel interior &Stainless steel interior &Stainless steel interior & exteriorexteriorexteriorexterior
Specifications:
Heated vacuum valve to prevent a vacuumwhen opening the door at short intervals
Digital controller with visual + acoustic alarms,remote monitoring and 72 hours battery
backup
Each freezer shelf is designed with holes foreasy access of CO2 liquid from top to bottom
Power consumption (kWh/24 h):Power consumption (kWh/24 h):Power consumption (kWh/24 h):Power consumption (kWh/24 h): 11111111
More environmentMore environmentMore environmentMore environmentArctiko would like to contribute to a more sustainable behaviour. That is why the
CO2Care concept has been introduced.More profitMore profitMore profitMore profit
Less emissions of CO2 serve both the environment and the profit.
Less energyLess energyLess energyLess energyOur CO2 care products are not only combining aesthetics and function, they are
noted for being extremely energy efficient compared to other products on the
market. That means less CO2 emission and a s ignificant saving on the electrical
bill.
More responsibilityMore responsibilityMore responsibilityMore responsibilityCO2 is the major culprit when it comes to climate changes.
Ultra lowtemperature
UprightULUF 400-450-800-850
UPUL (SS) 540-580
ChestULTF 80-320-420
OtherCryo Portor
MUF 33
Low temperature
UprightUPLTF 90-275
LF 140-300-500-660-
1400
PF 500-700-1400
ChestLTF 85-325-535
LTFE 140-290-370
Refrigerator
LaboratoryLR 170-270-300-390-500-
660-700-1400
PharmaPR 170-360-390-500-700-
1400
Blood & PlasmaBBR 500-700-1400
CO25DC
TE21AC
PBF 108-116-124
APPLITEK BIOTECH & LIFE SCIENCES GENERAL LABORATORY 3
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Laminar Flow cabinets
Fortuna Class IClass IClass IClass I Cabinets:
Advanced design for a clean working
environment. The Fortuna is a clean air cabinet
with vertical laminar flow, designed for the
ultimate product protection due to its unique
laminarity
Optimal Operator Comfort Low running costs due to strong fans,
low volume cabinet construction and
low energy transmission
Operator-friendly microprocessorcontrol
Designed for most applications
Mars Class IIClass IIClass IIClass II cabinets provide Optimal Operator Comfort Maximum Operator Safety Energy Saving Benefits with the especially designed EC-
fans which also provide lower noise level
Operator-friendly microprocessor control Eco-Save AutoStart AutoStop option Variety of options, including gas valves, Bunsen burner,
heated work top panel, marble insert for weighing
applications, built-in computer screen
Versions:
Type ApplicationMars-IVF In vitro
Fertilization
Integrated microscope and
heated/cool platens
Mars-Weigh
Master
Precise
weighing
Marble insert platform and
integrated computer screen
Mars-Iso Isotope Lead protection and Lead
glass to all windows
Orion Class II 100% exhaustClass II 100% exhaustClass II 100% exhaustClass II 100% exhaust cabinet:
Chemistry Inflammable liquids Chemicals and acids High concentration of organic
solvents explosion proof
version (a class II and fume
hood in one)
Animal Handling Surgery Cage Change Research (Manipulation)
General High concentration of odours Where recirculation can cause
disruption or disturbances
4 GENERAL LABORATORY APPLITEK BIOTECH & LIFE SCIENCES
Class I
FortunaUltimate product
protection
Titan
Designed for PCR andapplications requiring
sterility better than
Class 100
AtlasAdvanced design
providing operator
and environment
protection with built-
in exhaust fan
XITPortable cabinet with
recirculatory filtration
EXCELProviding horizontal
airflow away from the
operator
Class II
MarsOperator, product and
environment
protection with
recirculatory filtration
Mars Pro3 HEPA-filters
providing 99.999%
efficiency
SIRIUSDesigned for Class 2
work and handling of
medicine and
cytotoxics
ORION100% exhaust for work
with animal handling
or high
concentrations of
organic solvents
SPECIAL
DISCOUNTS
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Powder Handling & Containment Systems
XIT XIT Plus Excel Plus
Features
Compact size Quiet operation, less than
50d(B)A and low power
consumption
Fan speed pre-set foroptimum face velocities of
0.3 to 0.7 ms-1
Features
Same features as XIT and Safechange pre-filter bagged
under negative pressure
Chemcap filter for chemicalfume removal (Chemcap filter
type depending on Risk
Assessment Form)
Features
Aerofoils ensure an even flow across thewidth of the cabinet and the best
containment possible
A horizontal flow of airhorizontal flow of airhorizontal flow of airhorizontal flow of air, this flow can beset to a very low velocity, ideal for your
precision weighing jobs
Quiet operation, less than 50d(B)A andlow powerconsumption
Enclosures
Features:
Class II airflow patttern technology forbiohazards
Bigneat downflow air-draw protectiontechnology
Gives protection from moving parts,radioactivity and UV
Mobile or easily relocatable Ductless installation does not affect pressures
and flows in existing ducted systems
Avoids need for new cleanroom facilities
Releases fume cupboard space All-round visibility Compact enclosure solution
Options:
Climatic control Slide out trays and shelves
(easy removal of equipment, access when
servicing)
Emergency stop control Mechanical and electronic interlocks Variety or door arrangements
(sliding, wardrobe, bi-folding, vertically folding)
Leaded acrylic windows (for protection fromradiation)
Controlled atmosphere UV lamps
APPLITEK BIOTECH & LIFE SCIENCES GENERAL LABORATORY 5
XIT
supplied with
pre-filter and HEPA filter
dimensions
(W x D x H):
415 x 575 x 455 or
579 x 506 x 455
XIT Plus
supplied with
pre-filter and HEPA filter.
Low Flow Alarm
included
Dimensions from 770
mm to 1170 mm inwidth
UV Sterilisation cabinet
and PCR Workstation
Supplied with pre-filter
and HEPA-filter on PCR
cabinet only
*Powerful UV-lights
*All-round vision without
transmission of UV light
Excel Plus
supplied with
pre-filter and HEPA filter.
Ducted Model.Ducted Model.Ducted Model.Ducted Model. .Low
Flow Alarm included.
Dimensions from 770
mm up to 1470 mm in
width
Laminar Flow Cabinet
with Horizontal Clean Air
Operator or product
protection
Dust and Fumecontainment systems
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Centrifuges
Micro-centrifuge
Mini13.500 RPM
Acceleration time:
12 secDeceleration time:
16 sec
1524M15.000 RPM
5 Acceleration &
Deceleration levels
1730MR17.000 RPM
5 Acceleration &
Deceleration levels
Low SpeedCentrifuge
406G4.000 RPM
Acceleration time:
20 sec
Deceleration time:
20 sec
416G4.000 RPM
Acceleration time:
20 sec
Deceleration time:
20 sec
Multi-PurposeCentrifuge
1236MG12.000 RPM
5 Acceleration &
Deceleration levels
1580MGR15.000 RPM
5 Acceleration &
Deceleration levels
Main features of ScanSpeed centrifuges:
Quiet operation by way of a high torque AC induction motor The unique design of air-flow in non-refrigerated centrifuges protects samples from over-heating even at
high temperatures
Noise level lower than 60dB Easy to follow display and control panel Automatic RPM/RCF conversion Automatic detection with alarms for over-weight, over-speed and over-heating Safety lid-lock and lid-drop protection Emergency door-lock release (in case of power failure) Autoclavable and corrosion-resistant rotors with symmetrically numbered tube positions for easy loading Manufactured and tested according to the IEC 61010-20020 standards and regulations
Send us your tubes and we will custom-make
your ScanSpeed centrifuge adapters
6 GENERAL LABORATORY APPLITEK BIOTECH & LIFE SCIENCES
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Genetics
Thermal Cycler
GeneQ
Volumes:
18 x 0.5 ml
24 x 0. 2ml (8 strip - 24-
microplate)
Life Pro
96-microplate
96 x 0.2 ml
12 x 8-strip
Gene Pro
96-microplate
96 x 0.2 ml
12 x 8-strip
30 x 0.5 ml
384-microplate
ElectrophoresisSystems
Mini-Run
The GE-100 apparatuscan be used for agarose
gel electrophoresis.
Different gel sizes and
combs are available.
BioTANON
Horizontal system
Different gel sizes and
combs are available to
choose from. This allows
for a versatile system
with choice of sample
volume.
Mini vertical system
The gel size of 8.3 x
7.3cm (W x L) can be
used with different
combs to change
sample volume per well
Mini blotting system
The blotting system allows
for 2 gels(7.2 x 10) to be run
at the same time.
Thermal Cyclers Ultra low noise design Adjustable hot-lid pressure Gradient function Large screen USB storage function Network function Fast ramping rate (up to 4C/s for cooling or heating)
GeneQ Life Pro Gene Pro
Temp. Range 4~99,9C 4~99,9C 4~99,9C
Heating rate 5C/sec 4C/sec 4C/sec
Cooling rate 4C/sec 4C/sec 4C/sec
Block temp. Uniformity 0,2C 0,2C 0,2C
Gradient range N/A 1~30C 1~30C
Electrophoresis Systems
Horizontal systemagarose gel electrophoresis
Vertical system(SDS) PAGE electrophoresis
APPLITEK BIOTECH & LIFE SCIENCES GENETICS 7
Ultraviolet products and Accessories
Ultraviolet crosslinker Hybridization Ovens
Applications
Shortwave 254nm UV: UV crosslinkingmembranes
Longwave 365nm UV: UV curing, non-destructive testing
Midrange 302nm UV: Photochemicalreactions, UV crosslinking
The Vertical System is idealfor casting and running
SDS-PAGE gels. The Blotting
system provides rapid, high-
quality blotting of mini gels.
The precision heated and multifunctional hybridization
ovens feature accurate temperature and motion
controls, easy clean interior, stainless steel construction,
and a wide selection of models to meet individual user
or laboratory budgets and requirements. The dynamic
mixing capability is ideal for creating optimum
conditions needed for cDNA library screenings, primersynthesis and nucleicacid hybridization.Next to these products, we can also provide you with UV transilluminators,
UV lamps, UV meters, UV incubators and other Ultraviolet products.
NEW
The Horizontal System is idealfor casting and running
agarose gels. Supplied with a
Gel Caster which eliminates
the need for gel sealing tape
during gel casting.
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Bio Engineering
Freeze Drying
CoolSafeLaboratory Freeze dryers
CoolSafe
Temperature
-55 C*-95C*
-100C*
-110C*
*at 20C room
temperature
Volume (L)
4, 9 & 15
MaxiVac
Alpha BetaHeatSafe
Volumes (L)
4, 6, 8, 18 & 28
ChillSafe
Volumes (L)
8 & 18
Option
Power: extra strong
external circulation
pump for cooling
down over long
distances such as with
mass spectro-
photometres
Cryosafe
Temperature range
-50C to +150C
-90C to +150C
Volumes (L)
8 & 18
Specifications
seamless condenser with external cooling coil Wide range of Freeze Dryers Teflon coating (can work with very aggressive solvents and acids, e.g. TFA, DMSO, etc.) De-icing is very simple due to the external cooling coil Bench top or Floor standing Different Control options (Basic, PRO, PC option) Wide range of Accessories: Manifold with Cones for freeze drying flasks; Small Chamber
Accessories; Unheated Shelve Systems; Electrically Heated Shelves; etc.
MaxiVacCentrifugal evaporation
Alpha: Your solution for fast macro sample vacuum concentration
Beta: Your multi-purpose solution for low temperature macro sample
vacuum concentration and freeze drying
VacSafe
Vacuum Pumps
Circulators, Open Water Baths and Cryo BathsCirculators, Open Water Baths and Cryo BathsCirculators, Open Water Baths and Cryo BathsCirculators, Open Water Baths and Cryo Baths
Circulators
Versatile stand alone circulators for existing or new heated, cooling and cryo baths mounted on
bridges or clamps
HeatSafe
Powerful heating water baths available in different volumes with strong pump in highest Safety
Class 3 and high heating capacity of 2000 watt for fast heat up. Temperature range from +25C to
+150C
ChillSafe
Powerfull cooling chiller and bath with cooling capacity of 300 watt at 20C with strong pump in
highest Safety Class 3 and high heating capacity of 2000 watt. Temperature range from -35C to+150C
CryoSafe
Intelligent low temperature controlled cryo baths with excellent temperature control
8 BIO ENGINEERING APPLITEK BIOTECH & LIFE
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By providing more inc ubation c apacitymore incubation capacitymore incubation capacitymore incubation capacity,
in a smaller footprint, with more options
and a significant decrease i n risk ofdecrease in risk ofdecrease in risk ofdecrease in risk of
contaminationcontaminationcontaminationcontamination compared to water-
jacketed systems, Galaxy CO2 incubators
are easier to maintain, setup and utilize,
while providing superi or p erformancesuperior performancesuperior performancesuperior performance.
These elements have made Galaxy
systems a favourite among discerning
scientists in in-vitro fertilization (IVF),
stem cell research, as well as traditional
cell culture.
Laboratory Ovens
ThermoCenter
The ThermoCenter is an extremely versatile oven. It can be
used in R&D, QC as well as industrial applications. A must
when uniform temperature d istributionuniform temperature distributionuniform temperature distributionuniform temperature dist ribution and a highhighhighhigh
accuracyaccuracyaccuracyaccuracy are needed.
IncuCenter
The IncuCenter is a very versatile incubator. It can be used
in R&D, QC and industrial applications. This incubator is
advised when precise temperature distributionprecise temperature distributionprecise temperature distributionprecise temperature distributi on and a
very high accuracyvery high accuracyvery high accuracyvery high accuracy are needed.
Vacucenter
The VacuCenter Line is designed for all purposes of
vacuum dryingvacuum dryingvacuum dryingvacuum drying in a variety of laboratory fields. All systems
have a controller with alphanumeric display and
programming capabilities. Temperature ranges up to
200C.
Biocenter
The BioCenter is a CO2 incubat orCO2 incubatorCO2 incubatorCO2 incubat or designed to ensure
accurate and very reliable control of CO2, temperature and
humidity.
CO2 incubators
Bioprocessing
CO2 incubators
Volumes 14-170L,
up to 50C
Control of
CO2 (Uniformity0.1%)
Humidity (up to 95%)Temperature
(Uniformity 0.4C)
Options:
O2 control 72-hour data loggingLaboratory Ovens
ThermoCenter:
Determinetemperature,
temperature gradient,
timing and air
throughput Volumes 40-400L,
up to 285C
IncuCenter
Precise temperaturecontrol and process
monitoring
Volumes 40-400L,up to 110C
Vacucenter
Control temperature,timing and
evacuation level
Volumes 20-50L,up to 200C
Biocenter
Constant conditionsfor CO2, temperature
and humidity
Volume 175L, up to50C
APPLITEK BIOTECH & LIFE SCIENCES BIOPROCESSING 9
Laboratory heating
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LS-X / EX-X
These table top Lab-
shakers are very reliable
bench shaking units
made for continuous
maintenance free
operation with the
extremely efficient
Kuhner magnetic direct
drive.Tray sizes:
E 420 x 420 mm
EX 500 x 420 mm
F 820 x 420 mm
LT-X
The Lab Therm X (LT-X)
incubator shaker.
Certainly the most
reliable table top Shaker
incubator available
today. With the same
features and options as
the ISF1-X. Also
stackable (2 units) with a
king size EX tray of
500x420 mm
ISF1-X
The ISF1-X stackable
incubator shaker. Up to3 shakers use the same
floor space as 1 unit. For
ease of sterilizing and
cleaning an all stainless
steel interior. Very large
front windowdoor for
loading and observation
of the experiments at
close proximity without
having to open the door
ISF4-X
The ISF4-X incubator
shaker cabinet. The ideal
replacement or addition
to your environmental
rooms. Large shaking
capacity on a small floor
space. Up to 4 or 5
completely
independent shaking
units with individual
height settings. As with
all Khner shaker
incubators, an all
stainless steel interior
10 BIOPROCESSING APPLITEK BIOTECH & LIFE SCIENCES
Shakers
Benchtop shakers
Shaker-incubators
Accessories
LS-X ES-X
SHAKER TECHNOLOGY:
Built for continuous operation with a magnetic D.C. direct drive. Designed especially forshakers, extremely reliable, smooth running and quie tquietquietquiet whisper. Ver yVeryVeryVery energy efficientenergy efficientenergy efficientenergy efficient.
Change of shakingChange of shakingChange of shakingChange of shaking diameterdiameterdiameterdiameter possible.possible.possible.possible. The single eccentric system can be changed to3 different positions (Standard 12,5 25 50 mm) but other diameters possible)
NNNNo maintenanceo maintenanceo maintenanceo maintenance requiredrequiredrequiredrequ ire d. Designed to operate 24 hours a day for years to come. Orbital OR linear movement
CoolingCoolingCoolingCooling for temperatures below ambient. Controlled humidityControlled humidityControlled humidityControlled humidity with sensor, automatically refilled
water bath and window/door heating. Controlled CO2Controlled CO2Controlled CO2Controlled CO2 up to 20% CO2 for mammalian cells.
PhotosynthesisPhotosynthesisPhotosynthesisPhotosynthesis. UVUVUVUV lamp for sterilization. Darkened windowDarkened windowDarkened windowDarkened window. Pull out platformPull out platformPull out platformPull out platform. Dual tableDual tableDual tableDual ta ble: 2 levels
with a distance of 60/85/120mm allows the skaking of two trays.
LT-X ISF1-X ISF4-X
Trays withTrays withTrays withTrays with fixed stainless steel clampsfixed stainless steel clampsfixed stainless steel clampsfixed stainless steel clamps for Erlenmeyer-flasks, Fernbach-flasks, test-tube holders,
microtiter or deep well plates or any other kind of container. Trays with a washable self sticking matTrays with a washable self sticking matTrays with a washable self sticking matTrays with a washable self sticking mat
for shaking of Erlenmeyer flasks with speeds under 200 rpm. Trays with horizontal rubber coveredTrays with horizontal rubber coveredTrays with horizontal rubber coveredTrays with horizontal rubber covered
bars or traysbars or traysbars or traysbars or tra ys for separating vessels. Univers al tr aysUniversal traysUniversal traysUnivers al tr ays with treads which can be used with clamps from
25ml to 6000ml or adjustable test-tube holders.
The ES-X is especially designed for
installation in incubators. Intended
for working in high temperaturesand high humidity.
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- Flask
24 (or 96) singleuse and low costbioreactors permicrotiter plate
No well-to-wellcrosscontamination
Low evaporation Anaerobic (or high
CO2) cultivations
FlaskRAMConsistent growthConsistent growthConsistent growthConsistent growthand high cell densiand high cell densiand high cell densiand high cell densitiestiestiestiesbecause ofbecause ofbecause ofbecause of superiorsuperiorsuperiorsuperioroxygen transfer.oxygen transfer.oxygen transfer.oxygen transfer.Higher cell densityHigher cell densityHigher cell densityHigher cell densityand improvedand improvedand improvedand improvedconsistency = betterconsistency = betterconsistency = betterconsistency = betterprediction ofprediction ofprediction ofprediction ofdownstream stepsdownstream stepsdownstream stepsdownstream steps
High volume flasks Less sensitive to
higher viscositymedia bettermixing of thick mediatypes
6 fold better OTRsachieved comparedto orbital shakers dueprimarily to twothings:1.The power of theacoustic mixing
2.Active headspacerefreshment by theOxyPump
AFS(AlcoholFermentationSystem)
Robust and user-friendly parallelbioreactor for sixsimultaneous
anaerobic yeastfermentations
Highly accuratecarbon conversiondata, allowingresearchers toeasily monitorand improve theirprocess
Accuratecomparisons ofconversion ratesand yields underdifferent
conditionssuch astemperature,strain type, carbonsource ornutrients
---- Flask systemFlask systemFlask systemFlask system FlaskRAMFlaskRAMFlaskRAMFlaskRAM AFSAFSAFSAFS
Features:
Function Cultivation system with 24(96) individual micro-
reactors
Mixing incubator forgrowing flask cultures
Monitoring anaerobic,metabolic yeast activity
for alcohol production
Capacity
24 (or 96) wells per
microtiter plate
(up to 4 plates in 1 clamp)
18 x 250 ml
14 x 500 ml
8 x 1000 ml
6 x 250 ml
6 x 500 ml
Shaking Orbital Shaker Resonant Acoustic Mixing Magnetic Stirrer
Oxygen
Transfer Rate Up to 51 mmol O2/l/h
Up to 240 mmol O2/l/h
(with OxyPump)
Dependable on stirrer
speed
Monitoring N/A N/A Carbon conversion
Control N/ATemperature and
HumidityMixing and Temperature
Application areas:
Target culture Microbial & Cell Microbial Yeast
Examples
*DiscoveryDiscoveryDiscoveryDiscove ry of secondarymetabolites or new
enzyme activities
*High throughput
screeningscreeningscreeningscreen ing and construct
libraries
*Metabolic fluxMetabolic fluxMetabolic fluxMetabolic flux studies
*ComparativeComparativeComparativeComparative studies
*Growth mediumGrowth mediumGrowth mediumGrowth medium
optimizationoptimizationoptimizationoptimization
*Shake flask experiments
employing vis cous orviscous orviscous orviscous or
hard to mixhard to mixhard to mixhard to mix mediamediamediamedia
e.g. Biofuels applications
(aerobic though!),
Streptomyces
*Large volume flaskLarge volume flaskLarge volume flaskLarge volume flaskgrowthgrowthgrowthgrowth
e.g. pilot plant seed
cultures, research aterialproduction cultures
*Measure conver sionconversionconversionconversion
ratesratesratesrates of
-lignocellulose
hydrolysates into biofuels
- wort into beer
- grape juice into wine
*Test and comparecomparecomparecompare
- yeast strains
- feedstock/substrates
*QQQQualityualityualityuality control
*Alcohol tolerance andAlcohol tolerance andAlcohol tolerance andAlcohol tolerance and
toxicitytoxicitytoxicitytoxicity studies
Small Scale
APPLITEK BIOTECH & LIFE SCIENCES BIOPROCESSING 11
Bioreactor systems
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Laboratory Scale
Glass Autoclavable Systems
Single-Use AppliFlex
Autoclavablesystems
Available in singlewall and in jacketedversions. Up to 300Up to 300Up to 300Up to 300different modulesdifferent modulesdifferent modulesdifferent modulesare available tocustomizecustomizecustomizecustomize yourbioreactor system.
ModulesGas inlet and outletsystems; samplesystems; liquidaddition systems;agitators withvariety of impellers;liquid storagesystems; heatexchangers; baffles
Single use
The driving forcebasically iseconomical:
* Single-useproducts overcomethe costly cleaningprocedures that areinvolved in re-usabletechnologies.Various studies
describe andcompare these costeffects
* The lack ofvalidation issuesallows a shortertime to market forproducts producedin single-usesytems.
SIP
All internal parts inthe bioreactorshave anelectropolishedelectropolishedelectropolishedelectropolishedfinishfinishfinishfinish with an Ravalue of less than0.4 micrometer toensure reliablecleanability of thevessel andcomponents. Allstainless steelbioreactors andfermentors can beused incombination with aCleanCleanCleanClean----InInInIn----PlacePlacePlacePlace
system.
The systems are built according to the specific demands o f a process with
our standard elements. Because of the modularity and flexibility, the user
can always adapt the systems to changed process demands. This results in
low initial investment and low running costs.
Culture- Microbial
- Cell
Volume (L) 1 2 3 5 7 15 20
Aeration
- Stirrer
- Rotameter (up to 4)
- Mass Flow Controller (up to 4)
Temperature
regulation
- Heating blanket (optional
cooling valve)
- Thermocirculator
Application
Process optimization, screening studies,
product optimization, scale up/scale down
studies
Lipseal or
Magnetic stirrer
Benefits of single-use bioreactors include faster facility set-up, reduction
of down time, simplified validation, and more efficient use of plant floor
space. Disposable bioreactors greatly reduce the risk of cross-
contamination in multi product facilities.
Culture Cell
Volume (L) 10 20 50
Aeration- Rocking
- Gas in- and outlet lines
Application Mammalian cell based biotech
Stainless Steel Steam-In-Place Bioreactors
The BioBench bioreactors and fermentors are designed for research
applications such as process optimization.
Culture- Microbial
- Cell
Volume (L) 7 15 20 30
Aeration
- Stirrer
- Rotameter (up to 4)
- Mass Flow Controller (up to 4)
ApplicationProcess optimization, screening studies, product
optimization, scale up/scale down studies
12 BIOPROCESSING APPLITEK BIOTECH & LIFE SCIENCES
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Production ScalePilot Systems
Projects
In addition to our range of standard stainless steel bioreactors, we offer custom designed
systems. Please contact us for more information.
Process Control
BioSep
The upscaling of the SIP bioreactors provide the same features as
the Bio Bench bioreactors.
Culture
- Microbial- Cell
Volume (L)Microbial: 20 40 70 140
Cell: 30 60 130
Stirring
- Magnetically coupled stirrers- Top stirrers- Bottom drives
The ez-control regulates pH, Temperature, Dissolved Oxygen,
Foam/Level and Agitation. The colour touch screen interface
easily guides the user through operation of the controller. The
adaptive control features allow the user to focus on the process
while the controller keeps tight control on the important
process parameters. The system allows easy software updates
and communication through the integrated web server. The
optional ADDA board offers an additional 8 analog inputs, 4
analog outputs, 8 digital inputs and 8 digital outputs.
BiosepBiosepBiosepBiosep is an acousticacousticacousticacoustic separationseparationseparationseparation devicedevicedevicedevice. The
separation principle is purely based on gentle
acoustically induced loose aggregation
followed by sedimentation.
PerfusionPerfusionPerfusionPerfusion isisisis thethethethe technologytechnologytechnologytechnology totototo use,use,use,use,
providingprovidingprovidingproviding itsitsit sits users:users:users:users:
High cell density (over 10 mio cells/ml) High (volumetric) productivity: required
bioreactor volume can be reduced
dramatically (100-fold)
Cost-effective operation (reduced laborrequirements for bioreactor inoculation
and turnaround)
Pilot system
An electropolished
finish with an Ra
value of less than 0.4
micrometer and an
external, mirror-
polished finish of all
the standard
systems. All stainless
steel bioreactors andfermentors can be
used in combination
with a CleanCleanCleanClean----InInInIn----
PlacePlacePlacePlace system.
The process
parameters of the
systems can be
controlled by both
ez-Control and i-
Control systems.
Ez-Control
Easy operation
Security
Easy updates
Advanced computer
interface
Easy communication
Expandability
The i-control is
available for industrial
bioreactor control
system and utilityconsole
BioSep
Using high frequency
resonant ultrasonic
waves to separate cells
from product instead of
physical mes hor
membrane, it offers all
the benefits of
traditional devices butwithout their inherent
problems and
limitations.
Applications of BioSep:
- Cell retention
- Cell concentration
- Cell washing
R & D (min. 1L/day),
process development
(50 L/day) and
production scale
(1000L/day).
APPLITEK BIOTECH & LIFE SCIENCES BIOPROCESSING 13
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Polarimetry
*Full range of singl esinglesinglesingle
wavelengthwavelengthwavelengthwavelengthpolarimeters
*NIR SaccharimetersSaccharimetersSaccharimetersSaccharimeters
*Dual wavelengthDual wavelengthDual wavelengthDual wavelength
high accuracy
polarimeters
*Multi wavelengthMulti wavelengthMulti wavelengthMulti wavelength
high accuracy
polarimeters
*Comprehensive
range of glass, PTFE
and stainless steel
sample tubes
*Full range of
sample tubessample tubessample tubessample tubes in
both jacketed and
unjacketed form
*thermotubes
*Complete range of
quartz control plates
*Instruments and
quartz plates
available with UKAS
certificates
Refractometry
*GPR series are
temperature
controllable, to both
prism and sample
cover, by flowing
fluid from a
thermocirculater
temperature of
5C~70C
* PTR series
incorporating
electronic
temperature control
by Peltier Cell
technology
* Three models of
ATM X2 colorimeters
available, designed
specially for sugar
colour measurement.
14 CHEMISTRY APPLITEK BIOTECH & LIFE SCIENCES
Chemistry
Polarimetry
The PolAAr series of polarimeters and
saccharimeters consists of eight models
with the options of single wavelength,
dual wavelength or multi wavelength, a
choice oftwo or three figure accuracy,
and simple or full alphanumeric keypads.
Thermotubes
Accurate temperature control without athermocirculator
100 mm and 200 mm path lengths 8 mm and 4 mm diameter bore sizes Can be used in all our polarimeters Temperature range 15C to 30C
Refractometry
General Purpose refractometers (GPR)
Peltier controlled refractometers (PTR)
Visual/digital handheld refractometers
High temperature refractometers
Special purpose refractometers
ICUMSA colorimeters
UKAS calibration standards
GPR series refractometer with RIRIRIRI, BrixBrixBrixBrix (sucrose percent), temperature corrected Brix, temperaturecorrected RI and up to 10 calibrated scales are available.
PTR series refractometers with accurate temperature control, wide range of RI (1.32 - 1.68) and Brix (0 100%), resolution up to 0 .00001 RIresolution up to 0.00001 RIresolution up to 0.00001 RIresolut ion u p t o 0 .00001 RI, temperature range from 15C to 50C, multi-scale models and
full GLP capability
The GPR 12-70E refractometer is especially suited to high temperature measurements up to 100Cmeasurements up to 100Cmeasurements up to 100Cmeasurements up to 100C. Special purpose refractometers for the soft, carbonated and alcoholic beverage industries, for the
anaesthetic and petrochemical gas industries and for the contact lens industry.
Single and Dual wavelength ColorimetersColorimetersColorimetersColor imeters conform to I.C.U.M.S.A. method GS2/3-18 withwavelengths 420, 560 and 720 nmwavelengths 420, 560 and 720 nmwavelengths 420, 560 and 720 nmwavelengt hs 4 20, 560 and 720 nm. Highest accuracy for white sugar and longest path length 163
mm.
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APPLITEK BIOTECH & LIFE SCIENCES 15
AppliTek services & support at a glance
Belgium
Our people at your disposal Before and after purchase
The Biotechnology / Life Sciences department has its own entity inside
AppliTek. The sales and technical people you are in touch with only
deal with the products you rely on. A single point of contact is at your
disposal for product information, technical or commercial issues. For
urgent matters, you will be contacted to schedule assistance or
intervention, if needed.
In our documentation (written and electronic) we guarantee up to
date information about the product that you are looking for. All
information carrying specific details includes updated pictures. When
more information on a topic or system is required, our support team is
only a phone call away.
Value added services for support and maintenance
When you rely on AppliTeks portfolio for your research and lab
projects, you rely on premium quality products from established
manufacturers. On top of that, you can be assured that your facility is
in good hands. By working closely in collaboration with our suppliers,
we can provide you tailored service agreements and preventive
maintenance for your equipment and systems.
Language support: English Nederlands franais
Visit our renewed websitebiotech.applitek.com
Browse through our portfolio of lab equipment,specialty systems and accessories
Exclusive and limited offersRequest for quotation with priority through
AppliTek contact form
Receive our bimonthly newsletterContact details of our employees
Maintenance Intervention Checks
Personal contact Swift information
O n - l i n e
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AppliTek
Biotechnology / Life Sciences
Certified Sales & Service for Belgium
2010 AppliTek NV Printed in Belgium
AppliTek NV/SA
Industrial Zone De Prijkels
Venecoweg 19
B-9810 Nazareth
Belgium
Tel.: +32 9 386 34 02
Fax.: +32 9 386 72 97
E-mail: [email protected]
Visit us on biotech.applitek.com
AppliTek in Belgium Products, systems and accessoriesfor R&D, routine and process applications for the
biotechnological and pharmaceutical sectors
The Biotechnology/Life Sciences division of AppliTek concentrates since 1985
on the advice, sales and installation of products and systems designed for the
pharmaceutical industry, biotechnology companies and research faci lities.
AppliTek has a name one can trust in the pursuit of a long-term mutual
cooperation. For its top-notch suppliers, AppliTek is the authorized sales and
service center with an established infrastructure in the Belgian market.
Customers can rely on AppliTeks advice and supply of the finest dedicated
equipment, combined with differentiated and personal after-sales service.