2012 IR-4 Food Use WorkshopPatti Turner – Gowan Company

UPDATE:Fenazaquin Miticide(Food Use Registrations)

Product Overview

• Excellent contact activity and control of larval & adult mites

• True ovicidal activity on some mite eggs, reduces hatching

of mite eggs (except winter eggs)

• Excellent efficacy on key mite species

• Low use rate in the field: 100 to 200 g a.i./ha

• To be sold as 20% SC

• Currently marketed globally in over 60 countries

Fenazaquin Properties

• Fenazaquin is primarily a contact miticide• It is non-systemic/not translaminar• Rapid knockdown (24 hours)• Up to 25 days control• Fenazaquin is active independent of temperature

2013 Crops 2014 CropsPome FruitStone FruitCitrusStrawberriesVegetablesOrnamentals/NurseryHopsVines

CornAlfalfaCotton

NEW FUNGICIDE:GWN-10087

Overview

• Contact fungicide - penetrant activity providingprotectant, curative and eradicant control ofpowdery mildews.

• Unique mode of action (FRAC Code 29) forpowdery mildew fungicides

• Negligible resistance risk, valuable tool forresistance management.

• Registered beginning in 2007 on grapes,cucurbits and strawberries in UK, Italy, Romania,Tunisia, and Chile. More registrations pending.

Target Crops in North America

GWN-10087 formulation: 350 g/L EC• Grapes

• Apples

• Stone fruit

• Cucurbits

• Strawberries*

• Leafy vegetables

• Greenhouse Vegetables

• Other?

*nominated for minor use project in Canada

Efficacy

GWN-10087 is active against powdery mildew on awide range of crops:

• Grapes Uncinula necator• Pome Fruits Podosphaera leucotricha• Stone Fruits Sphaerotheca pannosa,

Podosphaera tridactyla• Tomato, Pepper Leveillula taurica• Cucurbits Erysiphe cichoracearum,

Sphaerotheca fuliginea• Strawberry Sphaerotheca macularis

Control of Powdery Mildew on Petunia

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•Michigan State University, June, 2012

•Rates expressed as rate/100 gallons of water, applied at 7 day•Intervals – Azoxystrobin & Triflumizole applied at 14 day intervals.•Ratings 0-10 scale – 0 healthy, 10= dead. Powdery mildew Oidium sp.•Petunia = Petunia x hybrida .

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Toxicity and Fate

• GWN-10087 shows low acute mammalian toxicityand no chronic toxicity issues:• Acute Oral LD50 - >2000 mg/kg• Acute Dermal LD50 - > 5000 mg/kg

• GWN-10087 shows favorable behavior in theenvironment• Readily degraded in soil and water through hydrolysis

and microbial degradation• Field half-life of 5 days

Environmental Toxicity

• GWN-10087 is highly toxic to fish andinvertebrates and moderately toxic to algae.

• However, GWN-10087 is not considered tocause unacceptable risk to aquatic organismsin surface water:• Tightly bound to soil so limited leaching potential• Rapidly degraded by microbes and hydrolysis

Environmental Toxicity

Test Species ResultAcute contact 72 hour LD50 Apis mellifera 84.8 g/bee Acute oral 72 hour LD50 Apis mellifera 90.0 g/bee Earthworm Acute 14 day LC50 Eisenia foetida 302 mg/kg soil

GWN-10087 is moderately toxic to earthwormsand bees

Environmental Toxicity

GWN-10087 shows an acceptable risk to non-target andbeneficial arthropods

Test Species ResultLaboratory Predatory mite

Typhlodromus pyri40.7 g ai/ha

Laboratory Parastoid waspAphidius rhopalosiphi

16.7% mortality at 840 g ai/ha28.8% effect on parasitism at 840 g ai/ha

Field studies revealed the following IOBC classification after4 consecutive applications:

•Typhlodromus pyri: •Harmless (class 1) : 89 % (n = 8)•Slightly harmful (class 2) 11 % (n = 1)

GWN-10087 Summary

• Preventative, curative, and eradicant control. • Unique mode of action amongst powdery mildew fungicides.• Excellent resistance management tool• Disease control not temperature dependent• Rainfast within 1 hour after application• No impact on wine fermentation or organoleptic properties of

wine.• Low acute and chronic mammalian toxicity.• Short half-life in the environment.• Safe to beneficial mites, can be used within Integrated Pest

Management (IPM) guidelines.

NEW BIOPESTICIDE:

GWN - 9996Repellent

• Over 10 years experience marketing an IGR biopesticide

• Acquisition of Dow’s Mpede and Scythe

• Acquisition of Agro Technology, S.A. (AGT)

• EcoFlora AGRO

GWN-9996 Overview

• Plant extracts of Liliaceae and Solanaceae plant families

• Activity: repellant• Anti-feedent• Anti-egg laying• Irritant

• Valuable tool for resistance management. • Ideal tool for IPM programs• Short REI and PHI• Field half-life up to 6 days• Shelf-life at least 2 years

Target Crops in North America

GWN-9996: concentrated EC formulation ofplant extracts

AsparagusTomatoBeansRoot & Tuber VegetablesLeafy VegetablesCucurbitsBulb VegetablesLeafy BrassicaCole CropsForages (alfalfa, clover, trefoil, vetch)

Pome FruitStone FruitGrapeStrawberryBerry GroupHerbs & SpicesTree NutsOrnamentals

Toxicity

• Recognized as low risk for human and ecological systems

• Slight eye and skin irritant

• Low persistence in the environment

• Minimal impact on beneficial and non-target organisms – timing is key

Efficacy

GWN-9996 efficacy has been proven in a widerange of crops against many mite and insect pestsincluding:

• Mites (Tetranychus sp., Polyphagotarsonemus latus, Phyllocoptruta oleivora, Brevipalpus phoenicis, Steneotarsonemusspinki, Oligonychus spp, , Panonychus spp.)

• Thrips (Thrips spp. Frankliniella sp., Scirtothrips citri)

• Psyllids (Bactericera cockerelli, Diaphorina citri)

• Coffee Berry Borer (Hypothenemus hampei (Ferrari)

……and the testing continues…….

GWN-9996 Summary

• Repellent

• Non-lethal mode of action

• Excellent resistance management tool

• Well suited to IPM programs

• Low mammalian and environmental toxicity.

• Short half-life in the environment.

• Safe to beneficial and non-target organisms

NEW BIOPESTICIDE:

GWN - 10198Fungicide

• A fungi based fungicide

• Demonstrated control of Verticillium dahliae which causes

wilt disease of strawberry

• Wettable Powder formulation

• Refinement of use pattern continues…….

• Submission timing 2015

Thank you for your attention!Questions?

Patti Turner – Registrations Manager (928)539-5467(pturner@gowanco.com)

Nikki Yepez– Registrations Specialist (928)539-1516(nyepez@gowanco.com)