2015 11-13 radboud technology centers dtl partner advisory committee
TRANSCRIPT
DTL Partner Advisory Committee meeting
Utrecht, 13 November 2015
Professor in Personalized Healthcare Head Radboud Center for Proteomics, Glycomics and Metabolomics Coordinator Radboud Technology Centers Senior Scientist Integrator - Biomarkers
Prof Alain van Gool
• Nijmegen, The Netherlands
• Mission: “To have a significant impact on healthcare”
• Strategic focus on Personalized Healthcare through “the patient as partner”
• Core activities:
• Patient care
• Research
• Education
• 11.000 colleagues
• 52 departments
• 3.300 students
• 1.000 beds
Radboud university medical center
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Radboud campus: - Radboudumc - Radboud University - Hogeschool Arnhem Nijmegen - Max Planck Institute - Multiple companies
Orientation across the spectrum from molecule to man to population
Ori
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tio
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cro
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the
spec
tru
m o
f d
isea
ses
PI
Research Theme
Te
chn
olo
gy
C
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Research support by Technology
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Radboudumc Technology Infrastructure
Get organised:
1. What technological expertise do we have and should we have ?
2. How should we organise this ?
3. How will we communicate this ?
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External role
Internal role
• Knowledge hub for technological expertise • Maximise use of available technical capabilities and knowledge (‘duurzaamheid’) • Advise scientists with technological expertise • Advise management on strategic investments and opportunities • Drive innovations by working with each other, research theme’s and Valorisation
• Easy access to Radboudumc’s technological expertise • Represent Radboudumc as one in external technology networks • Increase funding (grants, contract research)
Internal / external role
Radboudumc Technology Centers
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Technology Platforms UMC St Radboud
(Potential) Technology Platforms
Genomics
RPC
CMBI PRIME
MIC
CDL
CRCN
Radboud Biobank Malaria lab
Flow cytometry
TR&CT
TNU
MITeC
PDRC
December 2013
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Inventory phase
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Radboudumc Technology Centers
Genomics
Bioinformatics Animal studies
Flow cytometry
Translational neuroscience
Image-guided treatment
Imaging
Microscopy
Biobank
Data stewardship
Proteomics Glycomics
Metabolomics
Radboudumc Technology
Centers
GMP products
Clinical trials
January 2014
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Repositioning phase
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www.radboudumc.nl/research/technologycenters
Genomics
Bioinformatics
Animal studies
Stem cells
Translational neuroscience
Image-guided treatment
Imaging
Microscopy
Biobank
Health economics
Mass Spectrometry
Radboudumc Technology
Centers Investigational
products
Clinical studies
EHR-based research
Statistics
Human performance
Data stewardship
Molecule
Flow cytometry
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Implementation phase
Nov 2014 -
About 250 dedicated people working in 18 Technology Centers, ~1600 users (internal, external), ~140 consortia www.radboudumc.nl/research/technologycenters/
• Proteins • Metabolites • Drugs • PK-PD
• Preclinical • Clinical
• Behavioural • Preclinical
• Animal facility • Systematic review
• Cell analysis • Sorting
• Pediatric • Adult • Phase 1, 2, 3, 4
• Vaccines • Pharmaceutics • Cyclotron • Radio-isotopes • Malaria parasites
• Management • Analysis • Sharing • Cloud computing
• DNA • RNA
• Internal • External
• Early HTA • Evidence-based
surgery • Field lab
• Statistics • Biological • Structural
• Preclinical • Clinical • Economic
viability • Decision
analysis
• Experimental design • Biostatistical advice
• Electronic Health Records • Big Data • Best practice
• In vivo • Functional
diagnostics
• iPSC • Organoids
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Visibility
• Logo
• Key figures • Website • Leaflets
• Lectures
Combination of • Science • Business • Innovation • Impact in health www.radboudumc.nl/research/technologycenters/
(1H2015: 1.900 unique visitors, 26.000 page views)
Users Radboudumc Technology Centers
Internal researchers (often with external collaborators)
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External researchers (direct collaborations, public-private)
External fee for service (public-private)
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Working together on the Radboud campus
(Spin-out) companies
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Radboud Research Facilities • Shared facilities across Radboud campus, also made part of Gelderland facilities • Initiated by funding 6.2M Eur Gelderland + 6.2M Eur Radboud University/ Radboudumc
www.ru.nl/radboudresearchfacilities/ 15
Next steps
• Collaboration • Organisation of individual RTC’s • Interactions/collaborations/cross-selling between RTC’s • Research themes – Technology centers
• Networks • Local/regional/national/international
• Support • Cash, kind
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Use lessons learned for DTL?
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• Visualize DTL infrastructure 2.0 • Who, what, where? • Speciality? Quality? Accessibility? • Branding !! (eg. SciLifeLab)
• Define functional networks
• Coalition of the willing: based on mutual interest to collaborate (1+1=3) • E.g. Biobanks – facilities – data stewardship
• Funding should not be main driver
• Focus and get support • Define overarching theme and/or specialised focus areas
• E.g. Personalized Medicine & Health resp. Microscopy • Join forces in getting funding (NL (eg. NWO), EU (eg. ESFRI’s))
• Next steps
• Collaboration. Joined integrated D-T-L strategy. Focus. Action.