2019 chop research poster day · between fetal and adult hematopoietic stem cells. ......

2019 CHOP Research Poster DayAbstract Reference Guide

* Search for your abstract of interest by Department, Division, and Presenting Author

** Departments are color-coded; the Department text colors shown below will be indicated on each poster board for your reference at the event

Department DivisionPresenting Author

Last Name

Presenting

Author First

Name

Poster

Location/

Abstract

ID

Track Abstract Title

Anesthesiology

and Critical Care

Medicine

Critical Care Medicine Janowska Joanna 55 Translational

Mitochondrial Targeted Biofuels as

Countermeasures Against Chemical

Threats

Anesthesiology

and Critical Care

Medicine

Critical Care Medicine Moorthy Ganesh 96 Laboratory-basedA Microsampling Assay for

Vancomycin in Human Whole Blood

Anesthesiology

and Critical Care

Medicine

Critical Care Medicine Vedar Christina 153 Laboratory-basedA Microsampling Assay for Cefepime

in Human Whole Blood

Anesthesiology

and Critical Care

Medicine

General Anesthesiology Arnez Karina 6 Patient-oriented

Systematic Review of Pediatric

Preoperative Screening of Obstructive

Sleep Apnea and Anesthesia

Outcomes

Anesthesiology

and Critical Care

Medicine

Not Applicable Barr Stephen 10 Patient-orientedImplementation of a Pediatric Medical

Cannabis Research Program

Biomedical and

Health InformaticsNot Applicable Chen Changya 21 Laboratory-based

Spatial Genome Re-Organization

Between Fetal and Adult

Hematopoietic Stem Cells

Biomedical and

Health InformaticsNot Applicable He Bing 45 Laboratory-based

Landscape of Causal Noncoding

Mutations in Pediatric Cancers

Biomedical and

Health InformaticsNot Applicable Peng Tao 104 Laboratory-based

SCRABBLE: Single-Cell RNA-Seq

Imputation Constrained by Bulk RNA-

Seq Data

Biomedical and

Health InformaticsNot Applicable Stear Ben 132 Translational

Predicting Congenital Heart Defect

Risk From Maternal SNPs

Biomedical and

Health InformaticsNot Applicable Uzun Yasin 150 Laboratory-based

Risk Variants Disrupting Enhancers of

TH1 and TREG Cells in Type 1

Diabetes

Biomedical and

Health InformaticsNot Applicable Uzun Yasin 151 Translational

Constructing Gene Regulatory

Networks Using Multi-omics Data at

Single Cell Resolution

Nursing Not Applicable Broden Elizabeth 11 Patient-oriented

A “Good Death” in the PICU: A

Conceptual Model to Guide Bedside

Care and Future Research

Nursing Not Applicable Chen-Lim Mei Lin 23 Patient-oriented

Outcomes of Primary Care

Interventions to Impact Primary Care

Services and Non-Urgent Emergency

Department Use

Nursing Not Applicable Irving Sharon 54 Patient-oriented

Use of Mid Upper Arm Circumference

and Skinfold Measurements to

Evaluate Muscle and Fat Stores in

Infants With Congenital Heart

Disease

Nursing

Penn Research on

Vulnerable Women,

Children, and Families

Kumar Aparna 70 Patient-oriented

The Impact of Nursing Factors on

Mortality in Surgical Patients With and

Without Depression

Nursing Radiation Oncology Henry Elizabeth 47 Patient-oriented

Does Post-Anesthesia Active

Warming Effect Emergence Delirium

in Pediatric Oncology Patients

Receiving Daily Radiation Under

General Anesthesia?

Pathology and

Laboratory

Medicine

Cancer Pathobiology Arya Rahul 7 Laboratory-based

The Rag1 N-Terminus Promotes B

Cell Development via Post-

Transcriptional Shaping of the DSB

Response

Pathology and

Laboratory

Medicine

Cancer Pathobiology Charman Matt 19 Laboratory-based

Are All Viral Genomes Created Equal

or are Some Destined for Greater

Things?

Pathology and

Laboratory

Medicine

Cancer Pathobiology Dybas Joseph 33 Laboratory-based

Quantitative Proteomics Reveals Host

Protein Targets of HSV ICP0-

mediated Ubiquitination

Pathology and

Laboratory

Medicine

Cancer Pathobiology Herrmann Christin 48 Laboratory-based

Non-Degradative Ubiquitination of

RNA-Binding Proteins Promotes

Efficient Adenoviral RNA Processing

Pathology and

Laboratory

Medicine

Cancer Pathobiology Lee Kyutae 76 Laboratory-based

A Cis-Mediated Mechanism Inhibits

Intra-Allelic Dual TCRβ Chain

Expression to Suppress Autoimmunity

Pathology and

Laboratory

Medicine

Cancer Pathobiology Miot Charline 93 Laboratory-based

RAG1 N-terminus Reprograms

Thymocytes Proteome and Modulates

TCR Signaling

Pathology and

Laboratory

Medicine

Cancer Pathobiology Price Alexander 108 Laboratory-based

Adenovirus Co-Opts Cellular m6A

Modification Machinery to Facilitate

Viral RNA Splicing and Protein

Production

Pathology and

Laboratory

Medicine

Cancer Pathobiology Sehgal Priyanka 123 Laboratory-based

Myc Potentiates Wnt Signaling

Through Repression of the Novel Wnt

Antagonist DKK3

Pathology and

Laboratory

Medicine

Cancer Pathobiology Wu Glendon 158 Laboratory-basedDual TCRb Chain Expression

Encoded by One Tcrb Allele

Pathology and

Laboratory

Medicine

Cancer Pathobiology Yang Scarlett 159 Laboratory-basedRole of FBXW7 Isoforms in Normal

and Leukemic Human B Cells

Pathology and

Laboratory

Medicine

Cancer Pathobiology Zhao Mengge 165 Patient-oriented

Phen2Gene: Rapid Phenotype Driven

Gene Prioritization for Rare Diseases

Using Human Phenotype Ontology

Terms

Pathology and

Laboratory

Medicine

Cell Pathology Avery Lyndsay 8 Laboratory-based

Analysis of a Mouse-Model of X-

Linked Moesin-Associated

Immunodeficiency (XMAID)

Pathology and

Laboratory

Medicine

Cell Pathology Chen Yanqun 22 Laboratory-based

The Role of p27kip1 and CDK2

Activity in Regulatory T Cells Function

and Tolerance

Pathology and

Laboratory

Medicine

Cell Pathology Field Natania 37 Laboratory-based

The E3 Ubiquitin Ligase Itch

Attenuates CD4 T Cell Proliferation by

Limiting Wbp2 Protein Stability

Pathology and

Laboratory

Medicine

Cell Pathology Ricci Daniela 111 Laboratory-based

Clustering of IRE1α Depends on

Sensing ER Stress but is Distinct

From its RNase Activity

Pathology and

Laboratory

Medicine

Cell Pathology Roy Nathan 116 Laboratory-based

LFA-1 Signals via Crk Adapter

Proteins to Induce Actin-Dependent T

Cell Migration

Pathology and

Laboratory

Medicine

Cell Pathology Zhu Yueyao 167 Laboratory-basedType II Phosphatidylinositol 4-Kinases

Regulate Melanosome Biogenesis

Pathology and

Laboratory

Medicine

Center for Computational

and Genomic MedicineDemirdjian Levon 27 Translational

Detecting Allele-Specific Alternative

Splicing from Population-Scale RNA-

seq Data

Pathology and

Laboratory

Medicine

Experimental Pathology Liu Qian 82 Translational

Whole-Genome DNA Modification

Detection Using Nanopore

Sequencing and Deep Neural

Network

Pathology and

Laboratory

Medicine

Laboratory Medicine Doostparast Abolfazl 31 Translational

Deconvolution of Transcriptional

Networks Identifies TCF4 as a Master

Regulator in Schizophrenia

Pathology and

Laboratory

Medicine

Laboratory Medicine Keiser Megan 60 TranslationalCombinatorial Gene Therapy for

Spinocerebellar Ataxia Type 1

Pathology and

Laboratory

Medicine

Laboratory Medicine Kopinski Piotr 69 Laboratory-based Regulation of Nuclear Epigenome by

Mitochondrial DNA Heteroplasmy

Pathology and

Laboratory

Medicine

Laboratory Medicine Park Eddie 103 Laboratory-based

Population and Allelic Variation of A-

to-I RNA Editing in Human

Transcriptomes

Pathology and

Laboratory

Medicine

Laboratory Medicine Yrigollen Carolyn 160 Translational

Normalization of Fmr1 RNA and

Protein Expression in the Brains of

Mice That Model Fragile X Associated

Tremor/Ataxia Syndrome (FXTAS)

Using CRISPR-Cas9

Pathology and

Laboratory

Medicine

Laboratory Medicine Zhang Zijun 162 Patient-orientedDeep-Learning Augmented RNA-Seq

Analysis of Transcript Splicing

Pathology and

Laboratory

Medicine

Laboratory Medicine Zhang Yida 163 Laboratory-basedRegional Variation of Splicing QTLs in

the Human Brain

Pathology and

Laboratory

Medicine

Laboratory Medicine Zhao Juanjuan 164 Laboratory-based

Genomic Integration of ERRγ-HNF1β

Regulates Renal Bioenergetics and

Prevents Chronic Kidney Disease

Pathology and

Laboratory

Medicine

Not Applicable Adhikari Samir 1 Laboratory-basedSMARTer m

6A-Seq: Studying m

6A

RNA Methylome in Low Input

Biological Samples

Pathology and

Laboratory

Medicine

Not Applicable Ahsan Umair 2 Laboratory-based

NanoVar: A Deep Neural Network for

Accurate Detection of SNPs and

Indels From Long-Read Sequencing

Data

Pathology and

Laboratory

Medicine

Not Applicable Hu Yu 52 Laboratory-based

The Future of Metagenomics: A Pilot

Study of Single-Molecule Long-Read

Whole-Genome Shotgun Sequencing

of Reference Microbiomes

Pathology and

Laboratory

Medicine

Not Applicable PadmanabhuniShanmukha

Sampath100 Laboratory-based

Open Chromatin Mapping in T Helper

Cells Gives Insight Into Th1 and Th17

Lineage Relationships

Pathology and

Laboratory

Medicine

Protective Immunity Dar Asif 26 Laboratory-based

Cul4b and E3 Ubiquitin Ligase

Promotes T Cell Expansion and

Function

Pathology and

Laboratory

Medicine

Transplantation

ImmunologyHogan Michael 51 Laboratory-based

Immunization with Live Influenza

Virus Induces Greater Polyfunctional

CD4+ T Cell Response Compared to

Inactivated Virus

Pathology and

Laboratory

Medicine

Transplantation

ImmunologyKumar Binod 71 Laboratory-based

A Cullin E3 Ligase That Limits T Cell

Pathogenicity and Asthma

Pathology and

Laboratory

Medicine

Transplantation

ImmunologySharma Prabhat 126 Laboratory-based

Long-Range Cis-Regulatory

Architecture of the Human IL2 Gene

Pathology and

Laboratory

Medicine

Transplantation

ImmunologySu Chun 135 Laboratory-based

Open Chromatin-Promoter Interaction

Landscapes of Human Immune Cells

Reveal Regulatory Insight Into the

Genetic Basic of Nine Autoimmune

Diseases

Pathology and

Laboratory

Medicine

Transplantation

ImmunologyThomas Rajan 142 Laboratory-based

Foxp3 Cooperates With Ikaros to

Control the Suppressive Function of

Regulatory T Cells

Pathology and

Laboratory

Medicine

Transplantation

ImmunologyTorres Annabel 144 Laboratory-based

PAK6- A Novel Kinase in the

Maintenance of T Cell Anergy

Pediatrics Allergy and Immunology Carroll Margaret 17 Laboratory-based

Interleukin-13 Stimulation of

Esophageal Epithelial Barrier

Dysregulates Toll-Like Receptor 2-

Driven Barrier Effects

Pediatrics Allergy and Immunology Dilollo Julianna 29 Translational

Circulating T Cells in Eosinophilic

Esophagitis Patients Display Food

Allergen Specificity

Pediatrics Allergy and Immunology Khanna Caroline 62 Translational

Inflamed CVID Plasma Promotes

Naïve T-Cell Commitment to

Follicular Lineages

Pediatrics Allergy and Immunology Le Coz Carole 75 Translational

A CD25+ Tfh Cell Subset Promotes

Extra-Follicular IgM Autoantibody

Production in Common Variable

Immunodeficiency

Pediatrics Allergy and Immunology Maurer Kelly 87 Patient-oriented

Heterozygous De Novo OAS1

Mutations Were Detected in

Unrelated Patients

Pediatrics Allergy and Immunology Pappa Vasiliki 101 Translational

NK1R Signaling Activates the

Canonical NF-κB pathway in Human

Monocytes and Primes the NLRP3

Inflammasome in CD16+ Monocytes

Pediatrics Allergy and Immunology Ruffner Melanie 117 Laboratory-based

Improved Esophageal Barrier

Function Following Treatment With

TLR2 Agonists

Pediatrics Allergy and Immunology Ruffner Melanie 118 Patient-oriented

Elevated Allergic Comorbidity in

Patients with Food Protein-Induced

Enterocolitis

Pediatrics Allergy and Immunology Shi Lihua 128 Laboratory-based

Aberrant Central Cell Processes Link

Transcriptomic and Epigenetic

Analysis of Sorted Cells from Patients

with SLE

PediatricsBiostatistics and

EpidemiologyLabows Christina 74 Patient-oriented

Teaching Autistic Adolescents and

Young Adults to Drive: Perspectives

of Specialized Driving Instructors

Pediatrics Cardiology Burstein Danielle 13 Patient-oriented

Successful Percutaneous Lymphatic

Intervention for Chylothorax After

Pediatric Heart Transplantation

Pediatrics Cardiology DiFusco Leigh Ann 28 Patient-oriented

Parent Experiences in Caring for a

Child with a Ventricular Assist Device

(VAD) at Home: A Qualitative Pilot

Study

Pediatrics Cardiology Edelson Jonathan 34 Patient-oriented

Post-Transplant Outcomes in

Pediatric Patients Receiving

Mechanical Circulatory Support: A

Multicenter Study from the

International Society for Heart and

Lung Transplantation (ISHLT)

Registry

Pediatrics Cardiology Edelson Jonathan 35 Patient-oriented

Mortality and Resource Utilization in

Pediatric Hypertrophic

Cardiomyopathy Patients With and

Without Genetic Disorders in the

United States

Pediatrics Cardiology Guerrero David 44 Laboratory-based

Nanocarriers with a Camptothecin-

Mitocan Codrug Suppress Tumor

Growth and Extend Survival in Models

of Chemosensitive and

Chemoresistant Neuroblastoma

Pediatrics Cardiology Rock Christopher 113 Laboratory-based

Two-Photon Microscopy Study of

Advanced Glycation Endproduct

Related Bioprosthetic Valve Structural

Degeneration

Pediatrics Dentistry Macaraeg Kristianne 83 Patient-oriented

Needs Assessment for Improved

Dental Care of Children With Autism

Spectrum Disorders

PediatricsDevelopmental and

Behavioral PediatricsMiller Luke 92 Patient-oriented

Metacognition: Connections Between

Self-Monitoring Abilities and Negative

Driving Outcomes

Pediatrics Emergency Medicine Chaudhary Sofia 20 Patient-oriented

How do Caregivers Feel About Being

Offered Gun Safety Devices in the

Pediatric ED?

Pediatrics Emergency Medicine Feske-Kirby Katherine 36 Patient-oriented

Post-Traumatic Stress Symptoms

Following Pediatric Interpersonal

Assault: Opportunities for

Identification and Intervention

Pediatrics Emergency Medicine Pulcini Christian 109 Patient-oriented

Patient Satisfaction With Provider

Performance and Associations With

Patient, Provider and Visit Factors in

the Pediatric Emergency Department

Pediatrics Endocrinology Hitt Talia 49 Patient-oriented

Parents Seeking Height-Related

Medical Care in an Endocrine Clinic

Have Different Motivating Factors

Than Parents in Primary Care and

Hold High Expectations for Quality of

Life Benefit with GH Therapy

Pediatrics Endocrinology Hitt Talia 50 Patient-oriented

Fear of Hypoglycemia Impacts Quality

of Life in Adolescents with Type 1

Diabetes

Pediatrics Endocrinology Joshi Apoorva 56 Translational

Maternal Obesity and

Perfluorooctanoic Acid Synergize to

Alter Lipid Metabolism in Human Fetal

Hepatocytes Predisposing the

Offspring to NAFLD

Pediatrics Endocrinology Kilberg Marissa 64 Patient-oriented

Dysregulated Insulin in Pancreatic

Insufficient Cystic Fibrosis With Post-

Prandial Hypoglycemia

Pediatrics Endocrinology Kilberg Marissa 65 Patient-oriented

Phenotypic Variation, and Lack

Thereof, With Two Novel Mutations in

NR5A1

Pediatrics Endocrinology Lipman Terri 81 Patient-orientedRacial Disparities in Adverse Events

in Children With Type 1 Diabetes

Pediatrics Endocrinology Moss Nicholas 97 Laboratory-based

Role of H3K27 Demethylation in

Pancreatic Islet Cell Differentiation

and Maturation

Pediatrics Endocrinology Pinney Sara 106 Translational

In Utero Exposure to Gestational

Diabetes Alters the Transcriptome

and Methylome of Human Fetal Stem

Cells Revealing Enrichment of

Interferon Related Pathways

Pediatrics Endocrinology Rayannavar Arpana 110 Patient-oriented

Treatment of Post-Pancreatectomy

Diabetes in Individuals With

Congenital Hyperinsulinism Using a

Bihormonal Bionic Pancreas

Pediatrics Endocrinology Rosenfeld Elizabeth 114 Translational

Targeted Inhibition of Glutamate

Dehydrogenase (GDH) by Alpha-

Tocopherol: A Potential Novel

Treatment for

Hyperinsulinism/Hyperammonemia

(HI/HA) Syndrome

Pediatrics Endocrinology Schur Gayatri 122 TranslationalMRI Muscle-Bone Phenotyping in

Pediatric Mitochondrial Disease

Pediatrics Endocrinology Sigal Winnie 129 Patient-orientedSevere Infantile Insulin Resistance: A

Novel Feature of Mirage Syndrome

Pediatrics Endocrinology Tamaroff Jaclyn 138 Patient-oriented

Gonadal Function Following

Conservative Gonadal Surgery in Two

Cases of Ovotesticular DSD

Pediatrics Endocrinology Tamaroff Jaclyn 139 Patient-oriented

Not One, But Two Causes of

Hyperinsulinism in an Infant With

Persistent Hypoglycemia

Pediatrics Endocrinology Vazquez Diaz Sandra 152 Patient-oriented

Novel MYRF Mutation Associated

with Ambiguous Genitalia and Normal

Gonadal Function: A Case Report

Pediatrics Endocrinology Vishnu Neelanjan 154 Translational

Identification of Transcriptional

Networks Associated With Beta Cell

Functional Heterogeneity and

Dysfunction in Diabetes Using Single-

Cell Functional Genomics

PediatricsGastroenterology,

Hepatology, and NutritionKindler Joseph 66 Patient-oriented

Bone Density and Visceral Adiposity

in Youth With Type 2 Diabetes,

Obesity, and Healthy Weight


Hepatology, and NutritionKohut Taisa 68 Patient-oriented

The Use of Topiramate in Pediatric

Obesity


Hepatology, and NutritionMoore Hillary 95 Patient-oriented

Infliximab Trough Levels in Severe

Pediatric Ulcerative Colitis:

Preliminary Data of a Retrospective,

Population Cohort-Based Study


Hepatology, and NutritionSchrecengost Anna 121 Laboratory-based

Optimization of Next Generation

Sequencing Methods for

Characterizing the Urinary Tract

Microbiome

Pediatrics General Pediatrics Christie Melissa 24 Patient-oriented

Exploring Parental/Caregiver

Perceptions of Community

Connectedness Among Youth Ages

11 to 18 Years

Pediatrics Hematology Ayombil Francis 9 Laboratory-based

Acidic and Basic Residues Within

Factor V B-domain Impacts

Downregulation by APC

Pediatrics Hematology La Ping 73 Laboratory-based

An Orchestrated Balance between

Mitochondria Biogenesis, Iron-Sulfur

Cluster Synthesis and Cellular Iron

Acquisition

Pediatrics Hematology Petrillo Teodolinda 105 TranslationalThe Role of Factor V on the

Anticoagulant Effect of Protamine

Pediatrics Hematology Pires Lourenco Silvia 107 Translational

HbA and HbF Simultaneous Induction

by Double-Pronged Lentiviral Vector

ATM1.1 Outperforms Beta-Globin-

Based Gene Addition and miRNA-

Based Gamma-Globin Reactivation in

SCD-Derived Erythroblasts

Pediatrics Hematology Sarkar Amrita 119 Laboratory-based

A Heparin-Induced Thrombocytopenia

(HIT)-Like Monoclonal Antibody KKO

has Therapeutic Potential in a Murine

Endotoxemia Model

Pediatrics Hematology Sinha Sayantani 130 Translational

Elucidating the Role of IL6 in Stress

Erythropoiesis and in the

Development of Anemia Under

Inflammatory Conditions

PediatricsHuman Genetics and

Molecular BiologyAicher Joseph 3 Laboratory-based

Analysis of RNA Splicing in Clinically-

Accessible and Non-Accessible

Tissues: Relevance to Mendelian

Disease Diagnosis


Molecular BiologyArgenziano Mariana 5 Laboratory-based

High Resolution Genome-Wide

Promoter-Focused Connectome

Implicates Microglia Causal Genes for

Alzheimer’s Disease


Molecular BiologyCardinale Christopher 16 Laboratory-based

Regulation of Janus Kinase 2 by an

Inflammatory Bowel Disease Causal

Noncoding SNP


Molecular BiologyCohen Jennifer 25 Patient-oriented

The Utility of Early Tongue Reduction

Surgery for Macroglossia in Beckwith-

Wiedemann Syndrome


Molecular BiologyDuffy Kelly 32 Patient-oriented

Characterization of the Beckwith-

Wiedemann Spectrum: Validation of

the New Clinical Diagnostic Criteria


Molecular BiologyGarifallou James 39 Laboratory-based

Demonstration of the Successful

Extraction, Library Preparation, and

Sequencing of RNA from Exosomes

from Plasma/Serum Samples Frozen

from the Last Decade


Molecular BiologyGilhool Steven 41 Patient-oriented

Ancestry Clustering and Classification

Using an Autoencoder


Molecular Biology

Gonzalez-

GandolfiChristina 42 Patient-oriented

Reassessment of Beckwith-

Wiedemann Syndrome in Diverse

Populations in an Enlarged Cohort


Molecular BiologyKupa Jonida 72 Patient-oriented

Phenotypic Presentation of Children

Prenatally Suspected to Have

Beckwith-Wiedemann Syndrome


Molecular BiologyMafra Fernanda 84 Laboratory-based

High Efficiency Neurological Panel

Design Using Twist Bioscience

Double-Stranded Custom Targeted

Enrichment Probes and Capture

Optimization for Aged Dry Blood Spot

Samples


Molecular BiologyMarch Michael 86 Translational

Characterization of Lymphatic Anomly-

Associated Mutations in a Cell Model

System


Molecular BiologySheppard Sarah 127 Patient-oriented

Wiedemann-Steiner Syndrome in

Diverse Populations


Molecular BiologyTestori Alessandro 140 Translational

Genetic Analysis of Neuroblastoma in

African-American Children


Molecular BiologyTraxler Emily 145 Translational

Investigation of Gene Pathways

Leading to Cellular Overgrowth and

Cancer in Beckwith-Wiedemann

Syndrome

Pediatrics Infectious Diseases Kadry Nadia 57 Laboratory-based

Elucidating the Ability of the HMW1

and HMW2 Adhesins to Protect

Against Nasopharyngeal Colonization

by Nontypeable Haemophilus

influenzae

Pediatrics Infectious Diseases Karageorgos Spyridon 58 Translational

Using Preclinical Modeling to

Understand the Mechanisms by

Which Antibody Therapy Alters

Immunity Against High Risk

Neuroblastoma and Effects

Prolongation of Survival

Pediatrics Infectious Diseases Khurana Priya 63 Translational

Harnessing the Antitumor Activity of

Invariant Natural Killer T (iNKT) Cells

for Neuroblastoma Immunotherapy

Pediatrics Neonatology Gordon Scott 43 Laboratory-based

Interferons Drive Development of

Novel Interleukin-15-Responsive

Macrophages in the Uterus

Pediatrics Neonatology Kesman Russell 61 Patient-oriented

Transposition of the Great Arteries:

Delivery Room Management and

Short Term Outcomes

Pediatrics Neonatology Thom Christopher 141 Laboratory-based

Tropomyosin 1 Genetically Constrains

Hematopoiesis and Megakaryocyte

Development

Pediatrics Nephrology Levy Erez Daniella 77 Patient-oriented

The Impact of Pediatric Peritoneal

Dialysis on Caregivers’ Self-Reported

Health and Well-Being

Pediatrics Nephrology Levy Erez Daniella 78 Translational

Urinary CXCL10 and CXCL9 Are

Associated With Acute Kidney Injury

in Children After Hematopoietic Stem

Cell Transplantation: Results of a

Discovery and Validation Cohort

Pediatrics Neurology Roth Lindsay 115 Laboratory-basedMechanisms of White Matter Loss

due to Antiretroviral, Elvitegravir

Pediatrics Neurology Sonawane Poonam 131 Translational

Functional Characterization and

Effective Targeting of NRF1-BRAF

and ATG7-RAF1 Fusions Identified in

Anaplastic Pleomorphic

Xanthoastrocytoma Patients Without

BRAF p.V600E Mutation

Pediatrics Neurology Strachan Caitlyn 133 Patient-oriented

Stakeholder Perspectives in Peer

Mentoring Program for Solid Organ

Transplant Recipients

Pediatrics Neurology Uchitel Julie 146 Laboratory-based

Spatiotemporal Analysis of

Hippocampal Circuitry in the ArxGCG7

Mouse Model Using Voltage Sensitive

Dye Imaging

Pediatrics Oncology Buongervino Samantha 12 Translational

Elucidation of the Mechanisms of

Cytotoxicity of the GPC2-Targeting

Antibody-Drug Conjugate D3-GPC2-

PBD in High-Risk Neuroblastoma

Pediatrics Oncology Cahen Viviane 14 Patient-oriented

A Novel Approach to Estimating

Relapse and Hematopoietic Stem Cell

Transplant (HSCT) Incidence in a

National Pediatric Acute

Lymphoblastic Leukemia (ALL)

Cohort Using Pediatric Health

Information System (PHIS)

Administrative Data

Pediatrics Oncology Cahen Viviane 15 Patient-oriented

Estimating Septic Shock (SS)

Incidence in National Pediatric

Cohorts of Acute Lymphoblastic (ALL)

and Myeloid Leukemias (AML) Using

Pediatric Health Information System

(PHIS) and Merged Children’s

Oncology Group (COG) Data

Pediatrics Oncology Ding Yang 30 Translational

Synergistic Control Genes in Cancer

Gene Networks as Targets for

Combination Therapy

Pediatrics Oncology Gil-de-Gómez Luis 40 Laboratory-basedCD4

+ T Cells Mediate Dendritic Cell

Licensing to Promote Multi-Antigen

Anti-Leukemic Immune Responses

Pediatrics Oncology He Christy 46 Translational

Occurrence of Severe Left Ventricular

Systolic Dysfunction in Pediatric

Patients Treated for AML: A

Children's Oncology Group Report

Pediatrics Oncology Kingsley Molly 67 Laboratory-based

Tight Regulation of H3K79

Methylation Levels in KMT2A-

Rearranged AML

Pediatrics Oncology Modi Apexa 94 Laboratory-basedThe Landscape of Long Non-Coding

RNAs in Neuroblastoma

Pediatrics Oncology Noel Tiffany 98 Laboratory-based

MHC Antigen Discovery in

Neuroblastoma and Self-Antigen-

Directed CAR T Engineering

Pediatrics Oncology Riedel Simone 112 Laboratory-based

The Interaction Between the

Chromatin Remodeling Complex

mSWI/SNF and Meningioma-1 Drives

a Poor Prognostic Subgroup of Acute

Myeloid Leukemia

Pediatrics Oncology Upton Kristen 149 Laboratory-based

Validation of MYCN Repressed

Targets Identifies Downregulation of

Genes Necessary for the

Immunotherapy Response in

Neuroblastoma

Pediatrics Oncology Weiner Amber K. 155 Laboratory-based

Integrative Mass Spectrometry and

RNA-Sequencing Identifies DLK1 as

a Candidate Immunotherapeutic

Target in Neuroblastoma

Pediatrics Oncology Zha Ji 161 Laboratory-based

Bone Marrow Niche Dysfunction

Impairs Donor Hematopoietic Stem

Cell Engraftment after Transplantation

in a Mouse Model of Shwachman-

Diamond Syndrome

Pediatrics Oncology Zhu Qin 166 Laboratory-based

Developmental Bottleneck and

Population Heterogeneity During the

Formation of Hematopoietic Stem

Cells

Pediatrics Oncology Zukin Heather 168 Patient-oriented

Training in Problem Solving (TIPS) for

Caregivers of Childhood Brain Tumor

Survivors: Development and Initial

Feasibility of a Web-Based

Intervention

Pediatrics Rheumatology Nolan Brian 99 Laboratory-based

PU.1-Mutated Agammaglobulinemia,

a Novel Form of Congenital B-cell

Deficiency

Psychiatry and

Behavioral

Sciences

Child and Adolescent

PsychiatryLi Jianping 79 Laboratory-based

Mitochondrial Deficits in Human iPSC-

Derived Neurons From Patients With

22q11DS and Schizophrenia

Psychiatry and

Behavioral

Sciences

Child and Adolescent

PsychiatryManley Bill 85 Laboratory-based

Generating Pvalb-Fast Spiking

Interneurons From Human Stem Cells

Psychiatry and

Behavioral

Sciences

Oncology Miller Jacquelyn 91 Translational

Psychosocial Maturity, Posttraumatic

Growth, and Health-Related Quality of

Life in Adolecents and Young Adults

With Cancer

Psychiatry and

Behavioral

Sciences

Psychology Cesario Andrew 18 Patient-oriented

Exploring the Prevalence of Anxiety

and Externalizing and Internalizing

Problems in Urban Youth

Psychiatry and

Behavioral

Sciences

Psychology Udhnani Manisha 147 Patient-oriented

Sociodemographic Predictors of M-

CHAT Responses Among Children

who Screened Positive

Radiology Radiology Research Udupa Jayaram 148 Patient-oriented

Quantitative Dynamic MRI and Virtual

Growing Child 5D Functional Models

for Studying Thoracic Insufficiency

Syndrome

SurgeryGeneral, Thoracic, and

Fetal SurgeryHwang Rosa 53 Patient-oriented

An Enhanced Recovery After Surgery

Protocol in Children who Undergo

Nephrectomy for Wilms Tumor

Surgery Neurosurgery Galanaugh Jamie 38 Translational

A Novel Therapy for Glioblastoma

Using Human Stem Cell Derived

Interneurons as Therapeutic Vectors

Surgery Neurosurgery Straka Joshua 134 Laboratory-based

Novel NOTCH1-ROS1 Gene Fusion

in Pediatric Angiosarcoma Drives

Bipartite Oncogenic Mechanism and

is Targetable

Surgery Ophthalmology Lin Lisa 80 Patient-orientedOcular Findings in Children with

Headache

Surgery Ophthalmology Mcguire Ryan 88 Patient-orientedProgression From Pre-Plus Disease

to Plus Disease in the G-ROP Study

Surgery Ophthalmology Parikh Alomi O. 102 Patient-oriented

Practice Patterns Changes in the

Treatment of Retinopathy of

Prematurity

Surgery Ophthalmology Schein Yvette 120 Patient-orientedEmmetropization During Early

Childhood

Surgery Ophthalmology Tomlinson Lauren 143 Patient-oriented

Rationale, Design, and Subject

Characteristics of the Postnatal

Growth and Retinopathy of

Prematurity Validation Study (G-ROP)

Surgery Orthopaedics Angelozzi Marco 4 Laboratory-based

SOXC Transcription Factors are

Required for Intramembranous

Ossification by Controlling Progenitor

Cell Fate and Survival

Surgery Orthopaedics Kc Ranjan 59 Laboratory-based

SOX9 is Required to Prevent Growth

Plate Cartilage Closure but not to

Maintain the Overall Integrity of Adult

Articular Cartilage

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