2021 pediatric nutritional products guide

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2021 PEDIATRIC NUTRITIONAL PRODUCTS GUIDE

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Page 1: 2021 PEDIATRIC NUTRITIONAL PRODUCTS GUIDE

2021 PEDIATRIC NUTRITIONAL PRODUCTS GUIDE

Page 2: 2021 PEDIATRIC NUTRITIONAL PRODUCTS GUIDE
Page 3: 2021 PEDIATRIC NUTRITIONAL PRODUCTS GUIDE

ABBOTT PEDIATRIC NUTRITIONAL PRODUCTS GUIDE

WELCOME TO ABBOTT – PEDIATRIC NUTRITIONAL PRODUCTS

This product guide provides a detailed nutritional overview of our products intended for infants and children. Our goal is to help you provide the best care for your patient by helping you with product selection. An electronic version of this guide is available at abbottnutrition.ca and is updated on a regular basis.

Please refer to the product label for the most current information. Although every effort is made to ensure that all information is correct at the time of printing, values and instructions are subject to change.

ADDITIONAL INFORMATION

Health care professionals can contact their Abbott sales representative or:

Call: 1-866-767-7411, option 1 to speak to a product specialist or registered dietitian†

(7-day service)

Email: [email protected]

ORDERING

To order Abbott nutritional products, contact Customer Service.

Call: 1-866-767-7411, option 2Email: [email protected]

Monday – Friday8:30 a.m. – 5 p.m., ET

Thank you for choosing Abbott, a world leader in nutritional products for infants, children, and adults.

Your nutrition partnerLike you, we care

† Not meant to replace the advice of a health care professional.

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Continued on next page

TABLE OF CONTENTS

GENERAL INFORMATIONAbbott Hospital Feeding System (HFS) ...................................6

Indications for Use ...................................................................7

Allergens................................................................................10

Kosher and Halal ...................................................................11

Infant Formula Preparation Guidelines and Dilution Charts ................................................................12

Storage Guidelines ................................................................13

Recommended Hang Times ............................................14

Expiration Dates ...............................................................14

Warnings ...........................................................................14

Healthy Babies Begin with Healthy Moms ............................17

Caring for the Tiniest Patients ...............................................23

Breast Milk - Inspiring Our Research and Innovation ............51

Learn about scFOS ................................................................91

Pedialyte® Dosage Chart .....................................................111

PRODUCTS

Pregnant Women and Breastfeeding MomsSimilac Mom® ........................................................................18

Preterm InfantsSimilac® Human Milk Fortifier Extensively Hydrolyzed Protein Concentrated Liquid .................................................24

Similac® Human Milk Fortifier, powder ..................................28

Similac® Human Milk Fortifier Special Care® 30 (HFS) ...............32

LiquiProtein® .........................................................................36

Similac® Special Care® 20 (HFS) ..............................................38

Similac® Special Care® 24 (HFS) ..............................................40

Similac® Special Care® 24 High Protein (HFS) ...........................42

Similac® Neosure® .................................................................44

Similac® Neosure® (HFS) .......................................................46

Term InfantsSimilac Pro-Advance® Step 1, powder ..................................52

Similac Pro-Advance® Step 1 ................................................54

Similac Pro-Advance® Step 2 ................................................56

Similac® Advance® Step 1, powder ......................................58

Similac® Advance® Step 1 .....................................................60

Similac® Advance® Step 2 .....................................................62

Similac® Step 1 ......................................................................64

Similac® Step 2 ......................................................................66

Similac® Lower Iron ...............................................................68

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TABLE OF CONTENTS

Term Infants (continued)

Similac Total Comfort® ..........................................................70

Similac® Sensitive® Lactose Sensitivity ..................................72

Similac® Sensitive® Lactose Sensitivity (HFS) ........................74

Similac® Isomil® .....................................................................76

Similac® Isomil® (HFS) ...........................................................78

Similac® 24 (HFS) ...................................................................80

Similac® Alimentum® .............................................................82

Similac® Alimentum® (RTU) ...................................................84

Similac® Alimentum® (HFS) ...................................................86

Toddlers and ChildrenGo & Grow by Similac® Step 3 ..............................................92

Go & Grow by Similac® Step 3 (RTU) ....................................94

PediaSure Complete® Grow & Gain™ ..................................96

PediaSure Complete® Grow & Gain™ Reduced Sugar .........98

PediaSure® ..........................................................................100

PediaSure® Fibre .................................................................102

PediaSure® Plus ...................................................................104

PediaSure® Peptide 1 Cal ....................................................106

Specialty ProductsPedialyte® ............................................................................112

Pedialyte® AdvancedCare® Plus ..........................................114

Pedialyte® AdvancedCare® Plus Powder Sticks ..................116

Pedialyte® AdvancedCare® .................................................118

Pedialyte® Powder Sticks.....................................................120

Pedialyte® Freezer Pops ......................................................122

Pedialyte® (HFS) ..................................................................124

Similac® 5% Glucose Water (HFS) .......................................126

Similac® Sterilized Water .....................................................127

RCF® ....................................................................................128

AccessoriesComponent Nipple System .................................................133

Plastic Bottle and Cap .........................................................134

CustomFeed® Bottle and Volu-Feed® Dispensing Cap ...............135

Additional InformationAlberta Reimbursement List ............................................139

Ontario Reimbursement List ............................................140

Quebec Reimbursement List ...........................................141

Saskatchewan Reimbursement List..................................142

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ABBOTT HOSPITAL FEEDING SYSTEM (HFS)

Similac® has been trusted by health care professionals and parents for close to a century

Our hospital portfolio consists of scientifically formulated and researched products to help meet a wide range of infant, parental, and health care professional needs.

The most comprehensive line of hospital feeding system products, featuring:

• Powdered and liquid human milk fortifiers, including the first and only sterile human milk fortifier with extensively hydrolyzed protein unique to Abbott.

• An extensively hydrolyzed liquid protein modular product designed for use in preterm infants unique to Abbott.

• A variety of nutrient-enriched preterm formulas, including a post-discharge formula, with different energy and protein densities to meet the nutritional needs of preterm babies.

• An individually wrapped, sterile breast milk storage bottle (CustomFeed® bottle and cap) as well as other useful accessories, such as nipples and a 240-mL plastic bottle.

• A broad selection of term formulas: From starter formula to formulas designed for infants with allergies and nutritional sensitivities and formulas that address a wide range of parental preferences including non-GMO,† vegetarian, kosher, and halal.

• 2D matrix bar coding technology that allows for multiple track-and-trace capabilities‡ and includes product ID, expiration date, and batch/LOT number to help prevent misfeeds.

† Ingredients not genetically engineered.‡ Universal 2D matrix and linear barcode technologies can be read across various tracking systems.

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INDICATIONS FOR USE

Suggested indications do not replace the clinical judgment of the health care professional who is aware of the patient's complete medical history.

Please note that this is not a complete listing of all possible products/uses and that the products in each category are not listed in order of preference.

Allergy to Cow’s Milk ProteinSimilac® Alimentum®

Allergy to Cow’s Milk Protein where tolerance to soy has been established Similac® Isomil®

Human Milk Fortification OptionsSimilac® Human Milk Fortifier Extensively Hydrolyzed Protein Concentrated Liquid Similac® Human Milk Fortifier Special Care® 30 Similac® Human Milk Fortifier, powderLiquiProtein®

Burns (children 1-13 years of age)PediaSure®

PediaSure® FibrePediaSure® PlusPediaSure® Peptide 1 CalPediaSure Complete® Grow & Gain™PediaSure Complete® Grow & Gain™ Reduced Sugar

Celiac DiseaseAll Abbott nutritional pediatric products are gluten-free.

Colic Symptoms (due to cow’s milk protein sensitivity)Similac® Alimentum®

ColitisSimilac® Alimentum®

PediaSure® Peptide 1 Cal

Dehydration/Oral Rehydration Pedialyte® AdvancedCare® PlusPedialyte® AdvancedCare® Plus Powder SticksPedialyte® AdvancedCare®

Pedialyte®

Pedialyte® Powder SticksPedialyte® Freezer Pops

DiarrheaSimilac® Sensitive® Lactose SensitivitySimilac® Alimentum®

PediaSure® Peptide 1 CalPedialyte® AdvancedCare® PlusPedialyte® AdvancedCare® Plus Powder SticksPedialyte® AdvancedCare®

Pedialyte®

Pedialyte® Powder SticksPedialyte® Freezer Pops

Continued on next page

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Growth Faltering (children 1-13 years of age)PediaSure®

PediaSure® FibrePediaSure® PlusPediaSure Complete® Grow & Gain™PediaSure Complete® Grow & Gain™ Reduced Sugar

Fat Intolerance/MalabsorptionSimilac® Alimentum®

PediaSure® Peptide 1 Cal

Fussiness/GasSimilac Total Comfort®

Similac® Sensitive® Lactose SensitivitySimilac® Isomil®

Similac® Alimentum®

GalactosemiaSimilac® Isomil®Powder is the preferred form for infants with galactosemia.

Impaired Gastrointestinal FunctionSimilac® Alimentum®

PediaSure® Peptide 1 Cal

Inborn Errors of MetabolismSimilac® Isomil®

RCF®

Lactose Intolerance/SensitivityLactose is the main carbohydrate source in most Similac® formulas. Similac® Alimentum®, Similac® Sensitive® Lactose Sensitivity and Similac Total Comfort® are formulated with an alternate carbohydrate source and therefore contain only inherent sources of lactose (from the milk protein source). Similac® Isomil®, our soy-based, naturally lactose-free formula, is suitable for babies with galactosemia or congenital lactase deficiency.Most people with lactose intolerance can tolerate some amount of lactose in their diet. In fact, a review of the medical and scientific literature1,2 suggests that most could tolerate up to 6 g of lactose per serving. With improvements in testing methodology, low levels of lactose in nutritional products can now be detected. The products listed below contain less than 500 mg of lactose per serving and are therefore suitable for most people with lactose intolerance:

Similac Mom®

PediaSure®

PediaSure® FibrePediaSure® Plus PediaSure® Peptide 1 CalPediaSure Complete® Grow & Gain™ PediaSure Complete® Grow & Gain™ Reduced Sugar

INDICATIONS FOR USE

Continued on next page

REFERENCES: 1. Suarez F. Abbott Nutrition Medical assessment of lactose tolerancein the lactose maldigesters population. April 2007. 2. Hertzler SR,Huynh BC, Savaiano DA. How much lactose is low lactose? J Am DietAssoc 1996;96:243-6.

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Pre- and Post-Operative (children 1-13 years of age)PediaSure®

PediaSure® FibrePediaSure® PlusPediaSure® Peptide 1 CalPediaSure Complete® Grow & Gain™PediaSure Complete® Grow & Gain™ Reduced Sugar

Preterm/Low-Birth-Weight InfantsSimilac® Human Milk Fortifier Extensively Hydrolyzed Protein Concentrated Liquid Similac® Human Milk Fortifier Special Care® 30 Similac® Human Milk Fortifier, powderLiquiProtein®

Similac® Special Care® 20Similac® Special Care® 24Similac® Special Care® 24 High ProteinSimilac® Neosure®

Protein MaldigestionSimilac® Alimentum®

PediaSure® Peptide 1 Cal

Toddlers/ChildrenSimilac Pro-Advance® Step 2Similac® Advance® Step 2Similac® Step 2Go & Grow by Similac® Step 3PediaSure®

PediaSure® FibrePediaSure® PlusPediaSure® Peptide 1 CalPediaSure Complete® Grow & Gain™PediaSure Complete® Grow & Gain™ Reduced SugarPedialyte® AdvancedCare® PlusPedialyte® AdvancedCare® Plus Powder SticksPedialyte® AdvancedCare®

Pedialyte®

Pedialyte® Powder SticksPedialyte® Freezer Pops

INDICATIONS FOR USE

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Abbott realizes the importance of product information for you and your patients, especially when managing allergies and intolerances. Priority food allergens are listed following the ingredients list of each Abbott nutritional product in this guide.

The following foods or protein derived from one of these foods are considered priority food allergens in Canada:1• Peanuts• Eggs• Milk• Mustard• Tree nuts (almonds, Brazil nuts, cashews, hazelnuts,

macadamia nuts, pecans, pine nuts, pistachios, or walnuts)

• Wheat and triticale• Soy• Sesame seeds• Crustaceans• Shellfi sh• Fish

To confi rm the presence of any priority allergens, gluten, or added sulphites in a total amount of 10 ppm or more, please refer to the statement of food allergens, gluten source, and added sulphites on the label of the product.

ALLERGENS

REFERENCE:1. Government of Canada: Common food allergies Last modifi ed on 2018-05-14. [Accessed online on 2021-05-13].

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KosherAbbott nutritional products that are certified kosher have one of the following kosher indications on their label: kosher and dairy by U-D and pareve by U.

HalalAbbott nutritional products that are certified halal have the following halal indication on the product label:

For more information, visit www.ifanca.org.

The kosher and halal status is available on each product information page in this guide.

KOSHER AND HALAL

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INFANT FORMULA PREPARATION GUIDELINES AND DILUTION CHARTS

N/A: Not applicable.† Use only scoop provided in the container.‡ Values are approximate.§ Per 0.9-g packet.REFERENCE:1. Adapted from Young T, Mangum B. Dilution Tables Neofax 17th ed. Raleigh NC 2004:232.

FOR HEALTH CARE PROFESSIONAL USE ONLYAbbott data on calorically dense feedings is limited. Hypocaloric and hypercaloric formulas should be used under medical supervision.• 27 Cal/30 mL or more calorically dense formulas may

not supply enough water for some infants. Hydration status should be monitored and water supplied from other sources if necessary.

• When using a hypo- or hypercaloric formula, monitor the changes in vitamin and mineral status as well as gastrointestinal tolerance.

• For improved tolerance, it is best to increase caloric density slowly, by 2- to 4-Cal/30 mL increments.

Ready to use cans, 235-mL and HFS bottles• Do not dilute.Concentrated Liquid (40 Cal/30 mL)Standard dilution (20 Cal/30 mL) is one part concentrated liquid to one part water. See product label for detailed preparation instructions.Caloric Density1

(Cal/30 mL)Concentrated

Liquid (mL) +Water(mL) =

FinalVolume (mL)

20 (standard) 30 30 6024 90 60 15027 60 30 90

PowderStandard dilution (20 Cal/30 mL) is one level, unpacked scoop of powder for each 60 mL of water. See product label for detailed preparation instructions.Caloric Density1

(Cal/30 mL)Unpacked Level

Scoop(s)† +Water(mL) =

ApproximateYield‡ (mL)

20 (standard) 1 60 6022 2 105 12024 3 150 18027 3 130 150

Scoop Measurement and Displacement Volumesfor Infant Powders

Product

Grams of powder per

scoop

Displacement volume per scoop‡ (mL)

Displacement volume per g of

powder‡ (mL)

PretermSimilac® Neosure® 9.6 7.3 0.76Similac® Human Milk Fortifi er N/A N/A 0.69§

Term InfantsSimilac Pro-Advance® Step 1 8.6 6.5 0.76Similac Pro-Advance® Step 2 8.6 6.5 0.76Similac® Alimentum® 8.7 6.6 0.76Similac® Advance® Step 1 8.8 6.8 0.77Similac® Advance® Step 2 8.8 6.8 0.77 Similac® Step 1 8.8 6.8 0.77 Similac® Step 2 8.8 6.8 0.77Similac® Lower Iron 8.8 6.8 0.77 Similac® Sensitive®

Lactose Sensitivity8.7 6.7 0.78

Similac® Isomil® 8.9 6.8 0.76 Similac Total Comfort® 8.7 6.8 0.78 Go & Grow by Similac® Step 3 10.4 6.7 0.64

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TO ENSURE THE HIGHEST QUALITY OF UNOPENED PRODUCTS

Ready-to-use or concentrated liquid formats• Store at room temperature.

Avoid extreme temperatures. Do not freeze. While the product would remain sterile and the nutritional quality should not be affected, there could be changes to the physical consistency of the product that could affect its appearance, flavour, and other sensory attributes.

Powder• Store in dry, cool area.• Do not refrigerate.

GUIDELINES FOR PREPARING AND STORING FORMULA

Human Milk FortifiersSee individual product pages for storage instructions of:• Similac® Human Milk Fortifier Extensively Hydrolyzed Protein Concentrated Liquid• Similac® Human Milk Fortifier Special Care® 30• Similac® Human Milk Fortifier, powder• LiquiProtein®

Ready-to-use productsCans and bottles: after opening, cover, refrigerate, and use within 48 hours.

Concentrated liquid products• Open can (undiluted): cover, refrigerate, and use within

48 hours.• Prepare as per label instructions.• Pour into individual feeding bottles or cups, cover, and

store in refrigerator.• Use prepared formula within 48 hours.

Powdered products• Prepare as per label instructions.• Pour into individual feeding bottles or cups, cover, and

store in refrigerator.• Use within 24 hours.• Cover opened container after each use.• Use product within 1 month of opening container. - Similac® Isomil® should be used within 3 weeks of opening.

If ready-to-use, undiluted, or prepared formula is left opened at room temperature, it should be used within 2 hours.1

STORAGE GUIDELINES

Continued on next page

45°C40°C35°C30°C25°C20°C15°C10°C5°C0°C-5°C-10°C-15°C

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GUIDELINES FOR PREPARING AND STORING FORMULA (continued)

• Once feeding begins (first time the baby’s mouth comes into contact with the nipple), use within 1 hour or discard.

• Do not reuse plastic bottles.

If a product is consumed directly from the original container (includes use of a straw):†• Use or refrigerate within 1 hour.• If refrigerated, use product within 24 hours.

RECOMMENDED HANG TIMES

Ready to use (commercially sterile)• 4 hours for neonates and immunocompromised

infants/children.2• 8 hours for non-immunocompromised infants (>30 days of age) and children.2

Reconstituted formulasIncludes: Concentrated liquid, powder, any formula to which a modular product has been added, or fortified human milk.• Prepare using aseptic technique.• 4-hour hang times are recommended for human milk and facility-prepared formulas.2

It is recommended that feeding bags, containers, and tubing be replaced with each new hang time.2

Health care facilities should have guidelines in place for using safe techniques in the preparation and administration of feedings and should also have established quality assurance protocols for monitoring purposes.

EXPIRATION DATES

• To ensure the highest quality, use the product by the date indicated.

• The vitamin content and the physical stability of the product cannot be guaranteed beyond the expiry date because both may degrade with time.

WARNINGS

• Never use a microwave oven to warm formula; serious burns can result.

• Abbott nutritional products are not intended for parenteral use.

STORAGE GUIDELINES

† This practice exposes the product to significant amounts of bacteria.REFERENCES: 1. Government of Canada. Preparing and handling powdered infant formula. Last modified on 2021-04-16. [Accessed online on 2021-05-13]. 2. Steele C, Collins E (editors). Infant and Pediatric Feedings: Guidelines for Preparation of Human Milk and Formula in Health Care Facilities, 3rd Ed. Academy of Nutrition and Dietetics. 2019.

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Preg

nant Wo

men and

B

reastfeeding

Mo

ms

PREGNANT WOMEN AND BREASTFEEDING MOMSIN THIS SECTIONSimilac Mom®

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Pre

gna

nt W

om

en a

nd

Bre

astf

eed

ing

Mo

ms

PREGNANT WOMEN AND BREASTFEEDING MOMS

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HEALTHY BABIES BEGIN WITH HEALTHY MOMS

PREGNANT WOMEN AND BREASTFEEDING MOMS HAVE UNIQUE NUTRITIONAL NEEDS

Healthy eating plays an important role in a healthy pregnancy. A balanced diet helps support both the mom and the baby’s health – and provides specific nutrients that are particularly important during pregnancy, including protein, iron, calcium, vitamin D, vitamin B12, and folic acid.

Breast milk is the ideal food for babies,1 and breastfeeding moms require optimal nutrition to ensure they have enough energy to give their baby their best.

Similac Mom® is the first and only nutritional beverage for pregnant women and breastfeeding moms, to help them meet their nutritional needs.

For information on the complete Abbott adult nutritional product line, visit abbottnutrition.ca.

REFERENCE: 1. Health Canada, Canadian Paediatric Society, Dietitians of Canada, and Breastfeeding Committee for

Canada (2015). Nutrition for healthy term infants: Recommendations from birth to six months.

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SIMILAC MOM®

Complete, balanced nutritionFor pregnant women and breastfeeding moms

INDICATIONS FOR USE• For pregnant or breastfeeding women: - who would benefi t from a nutritious snack; - with increased caloric needs; - who require increased protein, vitamins and minerals.• To be used as part of an overall healthy diet that includes following

doctor’s recommendations for using prenatal vitamins.• For use with or between meals or, in appropriate amounts, as a

meal replacement.• Recommended intake: 1 serving per day along with the use of

prenatal vitamins.• For oral feeding only.Safety precautions:• Not for tube feeding and parenteral use.• Not intended for use in infants or children.

FEATURES AND BENEFITS• Complete, balanced nutrition.• Provides 26 vitamins and minerals.• Convenient source of protein and energy to help meet the

increased needs of pregnant women and breastfeeding moms.• Convenient, reclosable bottle.• 2 delicious fl avours: Vanilla and Chocolate.

TECHNICAL DATAReady to use

Caloric density (Cal/mL) 0.96Protein (% of total energy) 21Fat (% of total energy) 24Carbohydrate (% of total energy) 55Total Cal:g nitrogen ratio 122:1Non-protein Cal:g nitrogen ratio 96:1

Water (g/L) 837Osmolality (mOsm/kg water) 546Renal solute load (mOsm/L) 417Minimum tube size for gravity/pump feeding (Fr)

N/A

Low residue YesGluten-free YesKosher YesHalal Yes

AVAILABILITYReady to use56583848 Similac Mom®, Vanilla 235-mL bottles 4 x 6/case56584848 Similac Mom®, Chocolate 235-mL bottles 4 x 6/case

IMAGEBANKSEQ#14985

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NU

TRITIO

NA

L INFO

RM

ATIO

N

SIMILAC MOM®

Complete, balanced nutritionFor pregnant women and breastfeeding moms

ENERGYPer 100 mL Per 235 mL

ENERGY (Cal [kJ]) 96 (402) 225 (945)PROTEIN (g) 5.02 12% of total energy 21 Arginine (mg) - - Taurine (mg) - - Carnitine (mg) - -Source Sodium and calcium caseinates, soy protein isolateFAT (g) 2.55 6.0% of total energy 24 Polyunsaturates (g) 0.5 1.2 Linoleic acid (g) 0.43 1.0 Arachidonic acid (ARA) (g) - - Linolenic acid (g) 0.08 0.18 Docosahexaenoic acid (DHA) (g) - - Omega-6:Omega-3 ratio 7.4:1 Monounsaturates (g) 1.0 2.3 Saturates (g) 0.2 0.5Source High oleic saffl ower oil, canola oil, corn oil, soy lecithinMCT oil (% of total fats) 0CARBOHYDRATE (g) 13.2 31% of total energy 55 Fibre (g) - - Short-chain fructooligosac-

charides (scFOS) (g)- -

Galactooligosaccharides (GOS) (g) - -Source Sucrose, corn maltodextrinAcesulfame-potassium (mg) - -Sucralose (mg) - -

VITAMINSVitamin A (IU) 496 1166Vitamin D (IU) 21.3 50Vitamin E (mg) 1.07 2.5Vitamin K1 (mg) - -Vitamin C (mg) 6.4 15.0Thiamine (mg) 0.138 0.325Ribofl avin (mg) 0.184 0.432Niacin (mg NE) 2.55 6.00Vitamin B6 (mg) 0.20 0.47Folic acid (mg) 0.026 0.060Vitamin B12 (mg) 0.00021 0.00050Pantothenic acid (mg) 0.74 1.75Biotin (mg) 0.0149 0.035Choline (mg) - -

MINERALSSodium (mg) 123 290Potassium (mg) 182 428Chloride (mg) 107 251Calcium (mg) 117 275Phosphorus (mg) 117 275Magnesium (mg) 27.7 65Iron (mg) 1.49 3.50Zinc (mg) 1.70 4.00Iodide (mg) 0.017 0.040Copper (mg) 0.21 0.50Manganese (mg) 0.55 1.30Selenium (mg) 0.0051 0.012Chromium (mg) 0.0043 0.010Molybdenum (mg) 0.0119 0.028

Nutritional information for Similac Mom®, Vanilla, 235 mL.

INGREDIENTSSimilac Mom®, Vanilla:Water, sugar, sodium and calcium caseinate, corn maltodextrin, high oleic saffl ower oil, canola oil, soy protein isolate, corn oil, natural and artifi cial fl avours, soy lecithin, carrageenan, MINERALS (potassium citrate, sodium citrate, calcium phosphate, magnesium phosphate, magnesium chloride, salt, potassium phosphate, zinc sulphate, ferrous sulphate, manganese sulphate, cupric sulphate, potassium iodide, sodium molybdate, sodium selenate, chromium chloride), VITAMINS (ascorbic acid, niacinamide, dl-a-tocopheryl acetate, calcium D-pantothenate, vitamin A palmitate, pyridoxine hydrochloride, thiamine chloride hydrochloride, ribofl avin, folic acid, biotin, vitamin D3, cyanocobalamin).Contains: Milk, soy.

Additional ingredients for Chocolate: Cocoa powder, colour.

Values listed are subject to change. Please refer to the product label or packaging for the most current ingredient, allergen and nutrient profi le information.

INGREDIENTS LISTAS PER COMMODITY #C5921-01SEQ 14985

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NOTES:

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Preterm

Infants

PRETERM INFANTSIN THIS SECTIONSimilac® Human Milk Fortifier Extensively Hydrolyzed Protein Concentrated LiquidSimilac® Human Milk Fortifier, powderSimilac® Human Milk Fortifier Special Care® 30 (HFS)LiquiProtein®

Similac® Special Care® 20 (HFS)Similac® Special Care® 24 (HFS)Similac® Special Care® 24 High Protein (HFS)Similac® Neosure®

Similac® Neosure® (HFS)

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Pre

term

Infa

nts

PRETERM INFANTS

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CARING FOR THE TINIEST PATIENTS

ABBOTT – GIVING HEALTH CARE PROVIDERS THE POWER TO DO MORE

Without the chance to develop fully in utero, infants born prematurely are physiologically different from term infants. Early nutrition is a key factor in their survival. Each preterm baby has individual needs, and these needs vary over time after birth.

Human milk is the feeding of choice for preterm infants. However, neither human milk nor term infant formulas provide preterm and low-birth-weight babies with the necessary amounts of nutrients required for catch-up growth and optimal development. Human milk, once supplemented with human milk fortifier, provides adequate amounts of energy and most nutrients, with the exception of protein, which may require additional supplementation.1

Abbott has developed a wide range of infant nutritional products to help you meet the unique and varied nutritional needs of your preterm patients:

1) The most comprehensive line of human milk fortification options

• Similac® Human Milk Fortifier, powder

Unique to Abbott • Similac® Human Milk Fortifier Extensively Hydrolyzed Protein Concentrated Liquid • Similac® Human Milk Fortifier Special Care® 30 • LiquiProtein®

2) Preterm formulas, available in various caloric and protein densities

• Similac® Special Care® 20 • Similac® Special Care® 24 • Similac® Special Care® 24 High Protein Unique to Abbott – The Similac Liqui-MixTM

System allows health care professionals the flexibility to create a variety of calorically dense feedings using Similac® Special Care® formulas and Similac® Human Milk Fortifier Special Care® 30.

3) Preterm, post-discharge formula • Similac® Neosure®

REFERENCE: 1. Koletzko B, Poindexter B, Uauy R (eds). Nutritional Care of Preterm Infants: Scientific Basis and Practical Guidelines. World Rev Nutr Diet, Basel, Karger, 2014;110:215-27.

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SIMILAC® HUMAN MILK FORTIFIEREXTENSIVELY HYDROLYZED PROTEINCONCENTRATED LIQUIDFor preterm or low-birth-weight infants

INDICATIONS FOR USE• For preterm or low-birth-weight infants nourished with human milk that requires fortifi cation to meet elevated nutrient requirements.• Intended as a nutritional supplement to add to human milk.• For oral or tube feeding use.• Use under medical supervision.Safety precautions:• Add only to human milk − do not add water.• This product is nutritionally incomplete by itself and is designed to be added to human milk.• Additional iron may be necessary.• Tolerance to enteral feedings should be confi rmed by offering small volumes of unfortifi ed human milk.• Once enteral feeding is well established, Similac® Human Milk Fortifi er Extensively Hydrolyzed Protein Concentrated Liquid can be added to human milk.• Not intended for feeding low-birth-weight infants after they reach a weight of 3600 g (approximately 8 lb) or as directed by a health care professional.• Not for parenteral use.

FEATURES AND BENEFITS• Commercially sterile liquid: - a safer choice for preterm and low-birth-weight infants;1-3 - preferred for even distribution during mixing;3 - heat treated for sterility (non-acidifi ed).• Concentrated to minimize displacement; each packet displaces 5 mL.† • Extensively hydrolyzed protein for easy digestion and absorption.• When added to human milk, meets expert recommendations for protein4,5† and other nutrients for the preterm infant.4• Clinically proven to support weight, length, and head circumference gains in preterm babies.6-8

• Safe and well tolerated by preterm infants.6-8

• Contains an exclusive blend of DHA, lutein, and natural vitamin E,‡ all found in the infant brain and eyes.9-12

• Low iron level provides fl exibility to add iron as needed.

TECHNICAL DATAReady to mix

Caloric density (Cal/mL) 0.8§

Protein (% of total energy) 29.3Fat (% of total energy) 26.7Carbohydrate (% of total energy) 44.0Total Cal:g nitrogen ratio 85:1Non-protein Cal:g nitrogen ratio 60:1Water (g/30 mL) 25.3Osmolality (mOsm/kg water) 450§

Renal solute load (mOsm/L) 256§

Minimal tube size for gravity/pump feeding (Fr)

N/A

Low residue YesGluten-free YesKosher NoHalal No

AVAILABILITYConcentrated Liquid63010A14 Similac® Human Milk Fortifi er 24 x 5-mL 6 inner Extensively Hydrolyzed Protein packets/inner cartons/case Concentrated Liquid carton

† One packet mixed with 25 mL of human milk.‡ RRR-a-tocopherol provided as d-a-tocopheryl acetate, the most bioactive form of vitamin E. § Value based on 25 mL of Preterm Human Milk + 1 packet of Similac® Human Milk Fortifi er Extensively Hydrolyzed Protein Concentrated Liquid.

The FIRST and ONLYsterile human milk fortifi er

with extensively hydrolyzed protein

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SIMILAC® HUMAN MILK FORTIFIEREXTENSIVELY HYDROLYZED PROTEIN CONCENTRATED LIQUIDFor preterm and low-birth-weight infants

PREPARATIONThe health of the infant depends on carefully following the directions for preparation and use. Proper hygiene, handling and storage are important when preparing fortifi ed human milk. Follow directions as specifi ed. Improper dilution may be harmful.Similac® Human Milk Fortifi er Extensively Hydrolyzed Protein Concentrated Liquid (HMF HP CL) Mixing Chart

AdditionalCal desired

Preterm Human Milk SHMF HP CL

For initiation 2 Cal/30 mL 50 mL 1 packet (0.9 g)For full strength feeding 4 Cal/30 mL 25 mL 1 packet (0.9 g)Always wash hands thoroughly with soap and water when preparing infant feedings.1. Pour desired quantity of human milk into sterile feeding container.2. Product separation is normal. Massage contents until uniform.3. To open packet, tear top off completely along perforation.4. Add fortifi er to human milk and gently shake until mixed well.Storage• Refrigerate unused fortifi ed human milk and use within 24 hours.• After refrigeration, remix gently if needed. Feed promptly.• Keep unopened packets at room temperature in the protective carton; avoid extreme temperatures.ENERGY

Per 1 packet(5 mL)

Per 4 packets(20 mL)

ENERGY (Cal [kJ]) 7 (29) 28 (116)PROTEIN (g) 0.50 2.0% of total energy 29.3 Tyrosine (mg) 7.3 29.2 Leucine (mg) 35 140 Tryptophan (mg) 4.5 18.0 Carnitine (mg) 0.48 1.92Source Casein hydrolysateFAT (g) 0.21 0.84% of total energy 26.7 Linoleic Acid (g) 0.018 0.072 Arachidonic Acid (ARA) (g) 0.0043 0.0172 Linolenic Acid (g) 0.0022 0.0088 Docosahexaenoic Acid (DHA) (g) 0.003 0.012 Omega-6:Omega-3 ratio 4.5:1Source MCT oil, soy oil, coconut oil,

M. alpina oil, C. cohnii oilMCT oil (% of total fats) 44.9CARBOHYDRATE (g) 0.75 3.0% of total energy 44.0Source Corn maltodextrin, modifi ed corn starch

VITAMINSVitamin A (IU) 197 788Vitamin D (IU) 35 140Vitamin E (IU) 1.0 4.0Vitamin K (mg) 0.0024 0.0096Vitamin C (mg) 7.7 30.8Thiamine (mg) 0.048 0.192Ribofl avin (mg) 0.074 0.296Niacin (mg) 0.98 3.92Vitamin B6 (mg) 0.05 0.2Folic acid (mg) 0.007 0.028Vitamin B12 (mg) 0.00013 0.00052Pantothenic acid (mg) 0.31 1.24Biotin (mg) 0.0058 0.0232Choline (mg) 0.9 3.6Inositol (mg) 1.7 6.8Lutein (mg) 0.00306 0.01224

MINERALSSodium (mg) 5 20Potassium (mg) 21 84Chloride (mg) 13 52Calcium (mg) 30 120Phosphorus (mg) 17 68Magnesium (mg) 2.1 8.4Iron (mg) 0.11 0.44Zinc (mg) 0.31 1.24Iodine (mg) 0.0004 0.0016Copper (mg) 0.015 0.06Manganese (mg) 0.0022 0.0088Selenium (mg) 0.0002 0.0008Chromium (mg) – –Molybdenum (mg) – –

INGREDIENTSSimilac® Human Milk Fortifi er Extensively Hydrolyzed Protein, Concentrated Liquid:Water, Corn maltodextrin, Casein hydrolysate (milk), Modifi ed coconut and/or palm kernel oils (medium chain triglycerides), Calcium phosphate, Modifi ed corn starch, Soy oil, Coconut oil, Potassium citrate, Ascorbic acid, Magnesium chloride, M. alpina oil (a source of ARA), C. cohnii oil (a source of DHA), Potassium hydroxide, Potassium chloride, Salt, L-tyrosine, L-leucine, Monoglycerides, M-inositol, L-tryptophan, Choline chloride, Niacinamide, Zinc sulphate, D-alpha tocopheryl acetate, Gellan gum, L-carnitine, Calcium D-pantothenate, Ferrous sulphate, Vitamin A palmitate, Thiamine chloride hydrochloride, Pyridoxine hydrochloride, Ribofl avin, Vitamin D3, Cupric sulphate, Folic acid, Biotin, Manganese sulphate, Lutein, Phylloquinone, Beta-carotene, Sodium selenite, Cyanocobalamin. As needed: Potassium phosphate. Contains: Milk.

Values listed are subject to change. Please refer to the product label or packaging for the most current ingredient, allergen and nutrient profi le information.

INGREDIENTS LISTAS PER COMMODITY LIST #OL-065-3-02

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Nutrient Values of Preterm Human Milk (PTHM) + Similac® Human Milk Fortifi er Extensively Hydrolyzed Protein Concentrated Liquid (SHMF HP CL)

Per 100 CalENERGY

PTHM13¶ PTHM¶ + SHMF HP CL50 mL + 1 packet 25 mL + 1 packet

ENERGY (Cal) 100 100 100Volume (mL) 149 136 126PROTEIN (g) 2.10 2.97 3.58FAT (g) 5.80 5.32 4.98 Linoleic Acid (g) 0.55 0.499 0.464CARBOHYDRATE (g) 9.9 10.04 10.14

VITAMINSVitamin A (IU) 581 966 1238Vitamin D (IU) 3 89 149Vitamin E (IU) 1.6 3.8 5.3Vitamin K (mg) 0.0003 0.0062 0.0103Vitamin C (mg) 16 32.2 43.7Thiamine (mg) 0.031 0.144 0.224Ribofl avin (mg) 0.072 0.242 0.362Niacin (mg) 0.224 2.602 4.279Vitamin B6 (mg) 0.022 0.141 0.226Folic acid (mg) 0.0049 0.0213 0.0329Vitamin B12 (mg) 0.00007 0.00038 0.00060Pantothenic acid (mg) 0.269 0.987 1.494Biotin (mg) 0.0006 0.0148 0.0248Choline (mg) 14 13.8 13.7Inositol (mg) 22 22.4 22.7

MINERALSSodium (mg) 37 43 47 Potassium (mg) 85 122 148 Chloride (mg) 82 100 113Calcium (mg) 37 105 152Phosphorus (mg) 19 58 85Magnesium (mg) 4.6 9.0 12.1Iron (mg) 0.18 0.42 0.59Zinc (mg) 0.51 1.19 1.66Iodine (mg) 0.016 0.014 0.013Copper (mg) 0.096 0.116 0.131Manganese (mg) 0.0009 0.0062 0.0099Selenium (mg) 0.0020 0.0020 0.0020

OTHER CHARACTERISTICSPRSL (mOsm) 18.7 26.4 32Water (g) 131 117 106Osmolality (mOsm/kg water) 290 375 450

Per 100 mLENERGY

PTHM13¶ PTHM¶ + SHMF HP CL50 mL + 1 packet 25 mL + 1 packet

ENERGY (Cal) 67 74 79Volume (mL) 100 100 100PROTEIN (g) 1.41 2.19 2.84FAT (g) 3.89 3.92 3.94 Linoleic acid (g) 0.369 0.368 0.368CARBOHYDRATE (g) 6.64 7.40 8.04

VITAMINSVitamin A (IU) 390 713 982Vitamin D (IU) 2 65 118Vitamin E (IU) 1.1 2.8 4.2Vitamin K (mg) 0.0002 0.0045 0.0082Vitamin C (mg) 10.7 23.8 34.6Thiamine (mg) 0.021 0.106 0.177Ribofl avin (mg) 0.048 0.178 0.287Niacin (mg) 0.150 1.918 3.392Vitamin B6 (mg) 0.015 0.104 0.179Folic acid (mg) 0.0033 0.0157 0.0261Vitamin B12 (mg) 0.00005 0.00028 0.00047Pantothenic acid (mg) 0.181 0.728 1.184Biotin (mg) 0.0004 0.0109 0.0197Choline (mg) 9.4 10.2 10.8Inositol (mg) 14.8 16.5 18.0

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¶ The nutrient concentrations listed for preterm human milk are mean human milk levels. The range of nutrients in preterm human milk is highly variable. REFERENCES:1. Government of Canada. Preparing and Handling Powdered Infant Formula. Last modifi ed on 2011-04-16. [Accessed online on 2021-05-31]. 2. Centers for Disease Control and Prevention. Cronobacter Infection and Infants. Last reviewed on 2021-02-08. [Accessed online on 2021-07-06]. 3. Steele C, Collins E (editors). Infant and Pediatric Feedings: Guidelines for Preparation of Human Milk and Formula in Health Care Facilities, 3rd Ed. Academy of Nutrition and Dietetics. 2019. 4. Klein CJ. Nutrient requirements for preterm infant formulas. J Nutr 2002;132(6):1395S-1577S. 5. Agostoni C et al. Enteral Nutrient Supply for Preterm Infants: Commentary From the European Society for Paediatric Gastroenterology, Hepatology, and Nutrition Committee on Nutrition. JPGN 2010;58:85-91. 6. Kim JH et al. Growth and Tolerance of Preterm Infants Fed a New Extensively Hydrolyzed Liquid Human Milk Fortifi er. J Pediatr Gastroenterol Nutr 2015;61:665-71. 7. Kumar N, Monga R, Sampath V et al. Prospective Comparison of Enfamil and Similac Liquid Human Milk Fortifi er on Clinical Outcomes in Premature Infants. Am J Perinatol 2017;34(14):1411-6. 8. Schanler RJ, Groh-Wargo SL, Barrett-Reis B et al. Improved Outcomes in Preterm Infants Fed a Nonacidifi ed Liquid Human Milk Fortifi er: A Prospective Randomized Clinical Trial. J Pediatr 2018;202:31-7. 9. Krinsky NI, Landrum JT, Bone RA. Biologic mechanisms of the protective role of lutein and zeaxanthin in the eye. Annual Review of Nutrition 2003;23(1):171-201. 10. Vishwanathan R et al. Lutein and preterm infants with decreased concentrations of brain carotenoids. JPGN 2014;59(5):659-65. 11. Kuchan MJ et al.The naturally occurring alpha-tocopherol stereoisomer RRR-alpha-tocopherol is predominant in the human infant brain. Br J Nutr 2016;116(1):126-31. 12. Kuchan MJ, Moulton CJ, Dyer RA et al. RRR-a-Tocopherol Is the Predominant Stereoisomer of a-Tocopherol in Human Milk. Curr Dev Nutr 2018;2:nzy055. 13. Meeting the Special Needs of Low-Birth-Weight and Premature Infants in the Hospital (A8100). Columbus, Ohio: Abbott Nutrition, Abbott Laboratories, January 1998, p.56.

Per 100 mLMINERALS

PTHM13¶ PTHM¶ + Similac® HMF50 mL + 1 packet 25 mL + 1 packet

Sodium (mg) 25 32 37Potassium (mg) 57 90 118Chloride (mg) 55 74 89Calcium (mg) 25 77 121Phosphorus (mg) 13 43 67Magnesium (mg) 3.1 6.6 9.6Iron (mg) 0.12 0.31 0.47Zinc (mg) 0.34 0.87 1.32Iodine (mg) 0.011 0.010 0.010Copper (mg) 0.064 0.086 0.104Manganese (mg) 0.0006 0.0045 0.0078Selenium (mg) 0.001 0.002 0.002

OTHER CHARACTERISTICSPRSL (mOsm/L) 12.6 19.5 25.7Water (g) 88 86 84Osmolality (mOsm/kg water) 290 375 450

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SIMILAC® HUMAN MILK FORTIFIERFor preterm or low-birth-weight infants

INDICATIONS FOR USE• For preterm or low-birth-weight infants nourished with human milk

that requires fortifi cation to meet elevated nutrient requirements.• Intended as a nutritional supplement to add to human milk.• For oral or tube feeding use.• Use under medical supervision.Safety precautions:• Sterile liquids are preferred for infants who are premature, low-

birth-weight or immunocompromised.1 This product is not sterile and should only be used as directed by a health care professional.

• Tolerance to enteral feedings should be confi rmed by offeringsmall volumes of unfortifi ed human milk. Once enteral feeding iswell-established, Similac® Human Milk Fortifi er can be added tohuman milk.

• Not intended for feeding low-birth-weight infants after they reach a weight of 3600 g (approximately 8 lb) unless otherwise directed by a health care professional.

• Add only to human milk – do not add water.• Additional iron may be necessary.• Not for parenteral use.

FEATURES AND BENEFITS• Peer-reviewed studies have demonstrated: - Normal weight, length, and head circumference gains in preterm

infants.2 - Preserved antibacterial activity of human milk against Escherichia

coli, Staphylococcus, Group B Streptococcus, and Enterobacter sakazakii (now Cronobacter sakazakii).3

• Low iron content provides fl exibility to add iron as needed. • Mixes readily with human milk.• Small, convenient packaging.

TECHNICAL DATAReady to mix

(0.9 g powder)Caloric density (Cal/mL)† 0.77Protein (% of total energy) 28.2Fat (% of total energy) 21.1Carbohydrate (% of total energy) 50.7Total Cal:g nitrogen ratio 90:1Non-protein Cal:g nitrogen ratio 65:1

Water (g/L) 0Osmolality (mOsm/kg water)† 385Renal solute load (mOsm/L)† 231Minimum tube size for gravity/pump feeding (Fr)

N/A

Low residue YesGluten-free YesKosher YesHalal Yes

AVAILABILITYPowder54598934 Similac® Human Milk Fortifi er 50 x 0.90-g 3 inner cartons/ packets/ case inner carton

† Value based on 25 mL preterm human milk + 1 packet Similac® Human Milk Fortifi er.

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HUMAN MILK FORTIFIERFor preterm and low-birth-weight infants

PREPARATIONThe health of the infant depends on carefully following the directions for preparation and use. Proper hygiene, handling and storage are important when preparing infant feedings.

Similac® Human Milk Fortifi er Mixing ChartAdditionalCal desired

Preterm Human Milk

Similac® HumanMilk Fortifi er

For initiation 2 Cal/30 mL 50 mL 1 packet (0.9 g)For full strength feeding 4 Cal/30 mL 25 mL 1 packet (0.9 g)

1. Shake container of human milk. If frozen, thaw according to hospital procedure.

2. Pour desired quantity of human milk into sterile container; add Similac® Human Milk Fortifi er (as per mixing chart).

3. Shake gently and feed. 4. Bottle feeding: Discard any remaining product in the bottle within 1 hour

after feeding begins. Tube feeding: Hang for no more than 4 hours.45. Cover and refrigerate unused fortifi ed human milk immediately and use

within 24 hours.5 6. Store unopened packets at room temperature; avoid extreme

temperatures.

ENERGYPer 1 packet

(0.9 g)Per 4 packets

(3.6 g)ENERGY (Cal [kJ]) 3.5 (15) 14 (59)PROTEIN (g) 0.25 1.0% of total energy 28.2Source Nonfat milk, whey protein concentrateFAT (g) 0.09 0.36% of total energy 21.1Omega-6:Omega-3 ratio 7.5:1Source MCT oilCARBOHYDRATE (g) 0.45 1.8% of total energy 50.7Source Corn syrup solids, lactose

VITAMINSVitamin A (IU) 155 620Vitamin D (IU) 30 120Vitamin E (IU) 0.8 3.2Vitamin K (mg) 0.0021 0.0083Vitamin C (mg) 6.3 25Thiamine (mg) 0.058 0.233Ribofl avin (mg) 0.104 0.417Niacin (mg) 0.893 3.57Vitamin B6 (mg) 0.053 0.211Folic acid (mg) 0.00575 0.023Vitamin B12 (mg) 0.00016 0.00064Pantothenic acid (mg) 0.375 1.5Biotin (mg) 0.0065 0.026Choline (mg) 0.5 1.80Inositol (mg) 1 3.85

MINERALSSodium (mg) 4 15Potassium (mg) 16 63Chloride (mg) 9 38Calcium (mg) 29 117Phosphorus (mg) 16 67Magnesium (mg) 1.7 7.0Iron (mg) 0.08 0.35Zinc (mg) 0.25 1.0Iodine (mg) 0.0008 0.0016Copper (mg) 0.043 0.170Manganese (mg) 0.0018 0.0072Selenium (mg) 0.0001 0.0005Chromium (mg) - -Molybdenum (mg) - -

INGREDIENTSSimilac® Human Milk Fortifi er, Powder:Skim milk, Whey protein concentrate, Corn syrup solids, Modifi ed coconut and/or palm kernel oils (medium chain triglycerides), Calcium phosphate, Potassium citrate, Ascorbic acid, Magnesium chloride, Soy lecithin, Sodium chloride, Zinc sulphate, M-inositol, Niacinamide, Sodium citrate, D-alpha-tocopheryl acetate, Calcium pantothenate, Ferrous sulphate, Vitamin A palmitate, Copper sulphate, Ribofl avin, Thiamine chloride hydrochloride, Pyridoxine hydrochloride, Vitamin D3, Biotin, Folic acid, Manganese sulphate, Phylloquinone, Cyanocobalamin, Sodium selenate. As needed: Potassium phosphate, Potassium hydroxide, Calcium carbonate. Contains: Milk, Soy.

Values listed are subject to change. Please refer to the product label or packaging for the most current ingredient, allergen and nutrient profi le information.

INGREDIENTS LISTAS PER COMMODITY LIST C5907-01

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Nutrient Values of Preterm Human Milk (PTHM) + Similac® Human Milk Fortifi er (HMF)

Per 100 CalENERGY

PTHM‡ PTHM‡ + Similac® HMF50 mL + 1 packet 25 mL + 1 packet

ENERGY (Cal) 100 100 100Volume (mL) 149 137 127PROTEIN (g) 2.10 2.58 2.97FAT (g) 5.80 5.50 5.24 Linoleic Acid (g) 0.55 0.498 0.455CARBOHYDRATE (g) 9.9 10.2 10.4

VITAMINSVitamin A (IU) 581 944 1245Vitamin D (IU) 3 84 150Vitamin E (IU) 1.6 3.6 5.3Vitamin K (mg) 0.0003 0.006 0.010Vitamin C (mg) 16 31 44Thiamine (mg) 0.031 0.185 0.313Ribofl avin (mg) 0.072 0.347 0.574Niacin (mg) 0.224 2.611 4.587Vitamin B6 (mg) 0.022 0.162 0.278Folic acid (mg) 0.005 0.020 0.032Vitamin B12 (mg) 0.00007 0.0005 0.00085Pantothenic acid (mg) 0.269 1.256 2.072Biotin (mg) 0.0006 0.0181 0.0326Choline (mg) 14 14 14Inositol (mg) 22.0 22.5 22.9

MINERALSSodium (mg) 37 44 49Potassium (mg) 85 119 148Chloride (mg) 82 100 115Calcium (mg) 37 112 175Phosphorus (mg) 19 62 98Magnesium (mg) 4.6 8.9 12.4Iron (mg) 0.18 0.40 0.6Zinc (mg) 0.51 1.14 1.65Iodine (mg) 0.016 0.014 0.013Copper (mg) 0.096 0.202 0.289Manganese (mg) 0.001 0.006 0.010Selenium (mg) 0.0022 0.0023 0.0024

OTHER CHARACTERISTICSPRSL (mOsm/L) 18.7 24.5 29.3Water (g) 131 119 108Osmolality (mOsm/kg water) 290 343 385

Per 1000 mLENERGY

PTHM‡ PTHM‡ + Similac® HMF50 mL + 1 packet 25 mL + 1 packet

ENERGY (Cal) 671 731 790Volume (mL) 1000 1000 1000PROTEIN (g) 14.09 18.84 23.46FAT (g) 38.93 40.18 41.41 Linoleic acid (g) 3.691 3.642 3.594CARBOHYDRATE (g) 66.4 74.4 82.2

VITAMINSVitamin A (IU) 3899 6906 9834Vitamin D (IU) 20 612 1188Vitamin E (IU) 10.7 26.4 41.6Vitamin K (mg) 0.002 0.0429 0.0828Vitamin C (mg) 107 229 348Thiamine (mg) 0.208 1.355 2.471Ribofl avin (mg) 0.483 2.534 4.531Niacin (mg) 1.503 19.096 36.225Vitamin B6 (mg) 0.148 1.187 2.198Folic acid (mg) 0.033 0.146 0.256Vitamin B12 (mg) 0.00047 0.00362 0.00669Pantothenic acid (mg) 1.805 9.181 16.364Biotin (mg) 0.0040 0.1322 0.2571Choline (mg) 94 102 109Inositol (mg) 147.7 164.7 181.3

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‡ The nutrient concentrations listed for preterm human milk are mean human milk levels. The range of nutrients in preterm human milk is highly variable.6 Values for term human milk have been used for linoleic acid, biotin, choline, inositol, manganese, iodine, and selenium.7

REFERENCES:1. Government of Canada. Preparing and handling powdered infant formula. Last modifi ed on 2021-04-16. [Accessed online on 2021-05-30]. 2. Barrett-Reis B, Hall RT, Schanler RJ et al. Pediatrics 2000;106:581-8. 3. Chan GM. J Perinatol 2003;23:620-3. 4. Steele C, Collins E (Editors). Infant and Pediatric Feedings: Guidelines for Preparation of Human Milk and Formula in Health Care Facilities, 3rd ed. Academy of Nutrition and Dietetics. 2019. 5. Reali A, Greco F, Fanaro S et al. Early Hum Dev 2010;86:S33-6. 6. Meeting the Special Nutrient Needs of Low-Birth-Weight and Premature Infants in the Hospital (A8100). Columbus, Ohio: Abbott Nutrition, Abbott Laboratories, January 1998, p. 56. 7. American Academy of Pediatrics Committee on Nutrition: Pediatric Nutri-tion Handbook, 4th ed. Elk Grove Village: American Academy.

Per 1000 mLMINERALS

PTHM‡ PTHM‡ + Similac® HMF50 mL + 1 packet 25 mL + 1 packet

Sodium (mg) 248 319 388Potassium (mg) 570 874 1169Chloride (mg) 550 730 906Calcium (mg) 248 822 1381Phosphorus (mg) 128 456 777Magnesium (mg) 30.9 65.0 98.2Iron (mg) 1.21 2.92 4.58Zinc (mg) 3.42 8.31 13.07Iodine (mg) 0.107 0.106 0.105Copper (mg) 0.644 1.474 2.283Manganese (mg) 0.006 0.041 0.076Selenium (mg) 0.0148 0.0170 0.0192

OTHER CHARACTERISTICSPRSL (mOsm/L) 125.6 179.2 231.5Water (g) 879 867 856Osmolality (mOsm/kg water) 290 343 385

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SIMILAC® HUMAN MILK FORTIFIER SPECIAL CARE® 30 Liquid human milk fortifi erFor preterm or low-birth-weight infants

INDICATIONS FOR USE • For preterm or low-birth-weight infants who are nourished with human milk and require fortifi cation to meet their high nutritional needs.• To extend the volume of preterm human milk if mother’s milk

supply is limited.1• Can be mixed with human milk and fortifi ed human milk to a variety

of caloric densities.• Suitable for mixing with any Similac® Special Care® preterm infant

formula using the Similac Liqui-MixTM System to a variety of caloric densities.

• For oral or tube feeding use.• Use under medical supervision.Safety precautions:• For hospital use.• Follow hospital rules for safe handling of human milk and infant feedings.• Once tolerance to enteral feeding with human milk is well

established, Similac® Human Milk Fortifi er Special Care® 30 can be added to human milk.

• If signs of intolerance develop, slow feeding or discontinue.• Not intended for feeding premature infants after they reach a

weight of approximately 3600 g (approximately 8 lb) unless other-wise directed by the health care professional.

• Not for parenteral use.FEATURES AND BENEFITS• Sterile liquid formulation.

- Easy to mix.- When available, liquid human milk fortifi ers are preferable to

powders because they are sterile.2,3

- Safer choice for preterm and low-birth-weight infants under2 months of age or immunocompromised infants.3

• When mixed 1:1 with human milk:- Provides 25 Cal/30 mL (84 Cal/100 mL) to meet the energy needs

of most preterm infants.4,5

- Increases the calcium and phosphorus content of human milk to support growing bones.5,6

- Optimizes the nutrient content of human milk without increasing the osmolality: nearly isotonic at 310 mOsm/kg water.

• Exclusive blend of DHA, lutein, and natural vitamin E:† - Results of a clinical study point to protective effects of lutein on preterm retinal health and maturation.7• Non-GMO.‡

TECHNICAL DATAReady to mix

Caloric density (Cal/mL) 1.01Protein (% of total energy) 12.0Fat (% of total energy) 57.2Carbohydrate (% of total energy) 30.8Total Cal:g nitrogen ratio 215:1Non-protein Cal:g nitrogen ratio 189:1

Water (g/L) 850Osmolality (mOsm/kg water) 325Renal solute load (mOsm/L) 284Minimum tube size for gravity/pump feeding (Fr)

N/A

Low residue YesGluten-free YesKosher YesHalal Yes

AVAILABILITYReady to mix66357871 Similac® Human Milk Fortifi er 59-mL plastic 48/case Special Care® 30 bottles

Exclusive blend of DHA, lutein, and natural vitamin E†

† RRR-a-tocopherol, provided as d-a-tocopheryl acetate, the most bioactive form of vitamin E.‡ Ingredients not genetically engineered.

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NPREPARATIONProper hygiene, handling and storage are important when preparing infant feedings.1) Add fortifi er to desired quantity of human milk, fortifi ed human milk or

to any Similac® Special Care® preterm infant formula using the Similac Liqui-Mix™ System as specifi ed by a health care professional.

2) Gently swirl to mix.3) Warm as per usual nursery practices.4) Cover and refrigerate unused liquid fortifi er after opening; use

within 24 hours or discard.5) If feeding is not used immediately, cover prepared mixture and

store in refrigerator. Use within 24 hours2 or according to hospital procedure.

6) Once feeding begins, use within 1 hour or discard. For tube feedings, hang for no more than 4 hours.2

ENERGYReady to mixPer 100 mL

ENERGY (Cal [kJ]) 101 (424)PROTEIN (g) 3.0% of total energy 12.0 Taurine (mg) 5.6 Carnitine (mg) 4.6Nucleotides (mg) 7.2Source Dry or evaporated skim milk, whey protein concentrateFAT (g) 6.70% of total energy 57.2 Linoleic Acid (g) 0.71 Arachidonic Acid (ARA) (g) 0.025 Linolenic Acid (g) 0.098 Docosahexaenoic Acid (DHA) (g) 0.017 Omega-6:Omega-3 ratio 6.3:1Source MCT oil, soy oil, coconut oil, ARA and DHAMCT oil (% of total fats) 48.9CARBOHYDRATE (g) 7.8% of total energy 30.8 Fibre (g) - Short-chain fructooligosac-

charides (scFOS) (g)-

Galactooligosaccharides (GOS) (g) -Source Corn syrup solids, lactoseAcesulfame-potassium (mg) -Sucralose (mg) -

VITAMINSVitamin A (IU) 1270Vitamin D (IU) 152Vitamin E (IU) 4.1Vitamin K (mg) 0.012Vitamin C (mg) 38Thiamine (mg) 0.254Ribofl avin (mg) 0.629Niacin (mg) 5.07Vitamin B6 (mg) 0.254Folic acid (mg) 0.038Vitamin B12 (mg) 0.00056Pantothenic acid (mg) 1.93Biotin (mg) 0.038Choline (mg) 10Inositol (mg) 41Lutein (mg) 0.014

MINERALSSodium (mg) 49Potassium (mg) 140Chloride (mg) 82Calcium (mg) 183Phosphorus (mg) 101Magnesium (mg) 12Iron (mg) 1.8Zinc (mg) 1.5Iodine (mg) 0.006Copper (mg) 0.254Manganese (mg) 0.012Selenium (mg) 0.0020Chromium (mg) -Molybdenum (mg) -

INGREDIENTSSimilac® Human Milk Fortifi er Special Care® 30, Ready to mix:Water, Dry or evaporated skim milk, Corn syrup solids, Modifi ed coconut and/or palm kernel oils (medium chain triglycerides), Soy oil, Whey protein concentrate, Coconut oil, Lactose, Calcium phosphate, Ascorbic acid, Sodium citrate, M. alpina oil (a source of ARA), Calcium carbonate, Soy lecithin, Monoglycerides, Magnesium chloride, C. cohnii oil(a source of DHA), M-inositol, Potassium hydroxide, Carrageenan, Ferrous sulphate, Taurine, Choline bitartrate, Choline chloride, Niacinamide, Zinc sulphate, L-carnitine, D-alpha tocopheryl acetate, Cytidine 5'-monophosphate, Calcium D-pantothenate, Disodium guanosine 5'-monophosphate, Disodium uridine 5'-monophosphate, Adenosine 5'-monophosphate, Vitamin A palmitate, Thiamine chloride hydrochloride, Ribofl avin, Cupric sulphate, Potassium citrate, Pyridoxine hydrochloride, Folic acid, Biotin, Manganese sulphate, Lutein, Phylloquinone, Beta-carotene, Vitamin D3, Sodium selenate, Cyanocobalamin. As needed: Potassium phosphate, Potassium chloride. Contains: Milk, Soy.

Values listed are subject to change. Please refer to the product label or packaging for the most current ingredient, allergen and nutrient profi le information.

SIMILAC® HUMAN MILK FORTIFIERSPECIAL CARE® 30Liquid human milk fortifi erFor preterm or low-birth-weight infants

INGREDIENTS LISTAS PER COMMODITY #C6282-01 SEQ-15230

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Per 100 CalENERGY

PTHM8† PTHM† + SHMF SC30 2:1 RATIO 1:1 RATIO 1:2 RATIO

Cal/30 mL 20 23 25 27ENERGY (Cal) 100 100 100 100Volume (mL) 149 127 119 111PROTEIN (g) 2.10 2.49 2.64 2.78FAT (g) 5.80 6.15 6.29 6.41 Linoleic Acid (g) 0.550 0.615 0.640 0.663CARBOHYDRATE (g) 9.9 9.0 8.6 8.3

VITAMINSVitamin A (IU) 581 869 984 1084Vitamin D (IU) 3 66 91 113Vitamin E (IU) 1.6 2.6 3 3.4Vitamin K (mg) 0.0003 0.0053 0.0073 0.0091Vitamin C (mg) 16 25 29 32Thiamine (mg) 0.031 0.125 0.163 0.196Ribofl avin (mg) 0.072 0.308 0.402 0.484Niacin (mg) 0.224 2.28 3.098 3.813Vitamin B6 (mg) 0.022 0.12 0.159 0.193Folic acid (mg) 0.005 0.019 0.024 0.029Vitamin B12 (mg) 0.00007 0.00028 0.00036 0.00043Pantothenic acid (mg) 0.27 0.97 1.25 1.50Biotin (mg) 0.0006 0.0163 0.0225 0.0280Choline (mg) 14 12 12 11Inositol (mg) 22 30 33 36

MINERALSSodium (mg) 37 42 44 45Potassium (mg) 85 108 117 125Chloride (mg) 82 82 81 81Calcium (mg) 37 99 123 144Phosphorus (mg) 19 54 68 80Magnesium (mg) 4.6 7.8 9.1 10.2Iron (mg) 0.18 0.88 1.15 1.4Zinc (mg) 0.51 0.94 1.11 1.25Iodine (mg) 0.016 0.012 0.010 0.008Copper (mg) 0.096 0.162 0.189 0.212Manganese (mg) 0.001 0.0057 0.0076 0.0092Selenium (mg) 0.0022 0.002 0.002 0.002

OTHER CHARACTERISTICSPRSL (mOsm/L) 18.7 21.8 23.6 25.0Water (g) 131 111 103 96Osmolality (mOsm/kg water) 290 302 308 313

Nutrient Values of Preterm Human Milk (PTHM) + Similac® Human Milk Fortifi er Special Care® 30 (SHMF SC30)

† The nutrient concentrations listed for preterm human milk are mean human milk levels. The range of nutrients in preterm human milk is highly variable.

Per 100 mLENERGY

PTHM8† PTHM† + SHMF SC30 2:1 RATIO 1:1 RATIO 1:2 RATIO

Cal/30 mL 20 23 25 27ENERGY (Cal) 67 79 84 90Volume (mL) 100 100 100 100PROTEIN (g) 1.41 1.95 2.23 2.50FAT (g) 3.89 4.83 5.30 5.77 Linoleic acid (g) 0.369 0.483 0.54 0.596CARBOHYDRATE (g) 6.6 7.0 7.2 7.4

VITAMINSVitamin A (IU) 390 683 829 975Vitamin D (IU) 2 52 77 102Vitamin E (IU) 1.1 2.1 2.6 3.1Vitamin K (mg) 0.0002 0.0042 0.0062 0.0082Vitamin C (mg) 11 20 24 29Thiamine (mg) 0.021 0.098 0.137 0.176Ribofl avin (mg) 0.048 0.242 0.339 0.435Niacin (mg) 0.150 1.791 2.611 3.431Vitamin B6 (mg) 0.015 0.094 0.134 0.174Folic acid (mg) 0.003 0.015 0.020 0.026Vitamin B12 (mg) 0.00047 0.00022 0.0003 0.0004Pantothenic acid (mg) 0.18 0.76 1.05 1.35Biotin (mg) 0.0004 0.0128 0.0190 0.0252Choline (mg) 9.4 9.6 9.8 9.9Inositol (mg) 15 23 28 32

MINERALSSodium (mg) 25 33 37 41Potassium (mg) 57 85 99 112Chloride (mg) 55 64 69 73Calcium (mg) 25 77 104 130Phosphorus (mg) 13 42 57 72Magnesium (mg) 3.1 6.1 7.6 9.1Iron (mg) 0.12 0.7 1.0 1.3Zinc (mg) 0.34 0.74 0.93 1.13Iodine (mg) 0.0107 0.009 0.008 0.008Copper (mg) 0.0644 0.127 0.159 0.191Manganese (mg) 0.0006 0.0045 0.0064 0.0083Selenium (mg) 0.0015 0.002 0.002 0.002

OTHER CHARACTERISTICSPRSL (mOsm/L) 12.6 17.2 19.7 22.6Water (g) 88 87 87 86Osmolality (mOsm/kg water) 290 302 308 313

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Per 100 CalENERGY

FHM‡ FHM‡ + SHMF SC30 2:1 RATIO 1:1 RATIO 1:2 RATIO

Cal/30 mL 24 26 27 28ENERGY (Cal) 100 100 100 100Volume (mL) 127 116 111 106PROTEIN (g) 2.97 2.98 2.99 2.99FAT (g) 5.24 5.78 6.01 6.23 Linoleic Acid (g) 0.455 0.551 0.593 0.631CARBOHYDRATE (g) 10.4 9.4 8.9 8.5

VITAMINSVitamin A (IU) 1245 1247 1248 1249Vitamin D (IU) 150 150 150 150Vitamin E (IU) 5.3 4.8 4.6 4.4Vitamin K (mg) 0.010 0.0112 0.0114 0.0116Vitamin C (mg) 44 41 40 39Thiamine (mg) 0.313 0.813 0.655 0.509Ribofl avin (mg) 0.574 0.591 0.599 0.607Niacin (mg) 4.587 4.75 4.820 4.885Vitamin B6 (mg) 0.278 0.268 0.263 0.258Folic acid (mg) 0.032 0.034 0.035 0.036Vitamin B12 (mg) 0.00085 0.00073 0.00068 0.00063Pantothenic acid (mg) 2.072 3.695 3.190 2.726Biotin (mg) 0.0326 0.0343 0.0351 0.0358Choline (mg) 14 12 12 11Inositol (mg) 23 30 33 35

MINERALSSodium (mg) 49 49 49 48Potassium (mg) 148 144 142 141Chloride (mg) 115 102 96 90Calcium (mg) 175 177 178 179Phosphorus (mg) 98 99 99 100Magnesium (mg) 12.4 12.3 12.2 12.1Iron (mg) 0.6 1.85 1.83 1.82Zinc (mg) 1.65 1.59 1.57 1.54Iodine (mg) 0.013 0.010 0.009 0.008Copper (mg) 0.289 0.657 0.542 0.437Manganese (mg) 0.010 0.0106 0.011 0.0113Selenium (mg) 0.0024 0.002 0.002 0.002

OTHER CHARACTERISTICSPRSL (mOsm/L) 29.3 28.9 28.8 28.6Water (g) 108 99 95 91Osmolality (mOsm/kg water) 385 365 355 345

Nutrient Values of Fortifi ed Human Milk‡ (FHM) + Similac® Human Milk Fortifi erSpecial Care® 30 (SHMF SC30)

Per 100 mLENERGY

FHM‡ FHM‡ + SHMF SC30 2:1 RATIO 1:1 RATIO 1:2 RATIO

Cal/30 mL 24 26 27 28ENERGY (Cal) 79 86 90 94Volume (mL) 100 100 100 100PROTEIN (g) 2.35 2.58 2.69 2.81FAT (g) 4.14 4.99 5.42 5.85 Linoleic Acid (g) 0.359 0.476 0.535 0.593CARBOHYDRATE (g) 8.2 8.1 8.0 8.0

VITAMINSVitamin A (IU) 983 1078 1125 1173Vitamin D (IU) 119 130 135 141Vitamin E (IU) 4.2 4.1 4.1 4.1Vitamin K (mg) 0.0083 0.0096 0.00103 0.00109Vitamin C (mg) 35 36 36 37Thiamine (mg) 0.247 0.703 0.590 0.478Ribofl avin (mg) 0.453 0.511 0.540 0.570Niacin (mg) 3.623 4.106 4.347 4.589Vitamin B6 (mg) 0.220 0.232 0.237 0.243Folic acid (mg) 0.026 0.030 0.032 0.034Vitamin B12 (mg) 0.00067 0.00063 0.00061 0.00059Pantothenic acid (mg) 1.636 3.194 2.877 2.561Biotin (mg) 0.0257 0.0296 0.0316 0.0336Choline (mg) 11 11 11 10Inositol (mg) 18 26 29 33

MINERALSSodium (mg) 39 42 44 45Potassium (mg) 117 125 129 132Chloride (mg) 91 88 86 85Calcium (mg) 138 153 160 168Phosphorus (mg) 78 86 90 94Magnesium (mg) 9.8 10.6 11 11.4Iron (mg) 0.5 1.6 1.7 1.7Zinc (mg) 1.3 1.4 1.4 1.5Iodine (mg) 0.0105 0.009 0.008 0.008Copper (mg) 0.2283 0.567 0.489 0.411Manganese (mg) 0.0076 0.0091 0.0099 0.0106Selenium (mg) 0.002 0.002 0.002 0.002

OTHER CHARACTERISTICSPRSL (mOsm/L) 23.1 24.9 25.9 26.9Water (g) 86 85 85 85Osmolality (mOsm/kg water) 385 306 311 315

REFERENCES:1. Adamkin DH, Radmacher PG. Clin Perinatol (2014);41:405-21. 2. Steele C, Collins E (Editors). Infant and Pediatric Feedings: Guidelines for Preparation of Human Milk and Formula in Health Care Facilities, 3rd Ed. Academy of Nutrition and Dietetics. 2019. 3. Government of Canada. Preparing and handling powdered infant formula. Last modifi ed on 2021-04-16. [Accessed online on 2021-05-30]. 4. Willeitner A, Anderson M, Lewis J. JPGN 2017;65(5):574-8. 5. Klein CJ. J Nutr 2002;132:1395S-1577S. 6. Koletzko B, Poindexter B, Uauy R (eds): Nutritional Care of Preterm Infants: Scientifi c Basis and Practical Guidelines. World Rev Nutr Diet Basel, Karger., 2014;110:140-51. 7. Rubin LP, Chan GM, Barrett-Reis BM, et al. Effect of carotenoid supplementation on plasma carotenoids, infl ammation and visual development in preterm infants. J Perinatol 2012;32(6):418-24. 8. Meeting the Special Needs of Low-Birth-Weight and Premature Infants in the Hospital (A8100). Columbus, Ohio: Abbott Nutrition, Abbott Laboratories, January 1998, p. 56.

‡ 25 mL human milk + 1 packet Similac® Human Milk Fortifi er, powder.

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LIQUIPROTEIN®

Extensively hydrolyzed protein

INDICATIONS FOR USE• For use as a protein fortifi er with human milk or infant formula.• For preterm and low-birth-weight infants with increased protein needs.• Use as directed by a health care professional.Safety precautions:• Not for use as a sole source of nutrition.• Do not attach nipple or feed directly.• If signs of intolerance develop, slow feeding or discontinue.• Not for parenteral use.

FEATURES AND BENEFITS• A commercially sterile, extensively hydrolyzed liquid protein

modular; same trusted casein hydrolysate used in Similac® Alimentum®.

• Eliminates the need for protein powder mixing and meets Health Canada1 and other expert body recommendations2 to reduce the risk of contamination.

• Allows for customized protein intake.• Safe for preterm infants – study indicates good feeding tolerance

and growth when fed full strength fortifi ed human milk with the addition of LiquiProtein®.3†

• Minimal impact on osmolality; 1 mL contributes ~12 mOsm/kg water when 100-mL feeding is prepared; osmolality comparable to using Similac® Human Milk Fortifi er powder.‡

• Black cap for easy product identifi cation and distinguishing features on label designed to stand out from infant formulas.

• Lactose-free.§

TECHNICAL DATAReady to mix

Caloric density (Cal/mL) 0.67Protein (% of total energy) 100Fat (% of total energy) 0Carbohydrate (% of total energy) 0Total Cal:g nitrogen ratio 25:1Non-protein Cal:g nitrogen ratio N/A

Water (g/L) 810Osmolality¶ (mOsm/kg water) 240-450Renal solute load (mOsm/L) N/AMinimum tube size for gravity/pump feeding (Fr)

N/A

Low residue YesGluten-free YesKosher NoHalal No

AVAILABILITYReady to mix62317X31 (Pediatric) LiquiProtein® 54-mL plastic 48/case bottles

† 25 mL human milk + 1 packet Similac® Human Milk Fortifi er powder + 1 mL LiquiProtein®.‡ Osmolality when supplementing 25 mL of preterm human milk with an equivalent

of 0.25 g of protein from the following products:− 1 packet Similac® Human Milk Fortifi er powder: 385 mOsm/kg water;− 1.5 mL LiquiProtein®: 370 mOsm/kg water.

§ Not suitable for infants with galactosemia. ¶ As commonly fed - 1 to 6 mL of LiquiProtein® + human milk, fortifi ed human milk, or formula;

total volume of 100 mL.

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LIQUIPROTEIN®Extensively hydrolyzed protein

PREPARATIONThe health of the infant depends on carefully following the directions for preparation and use. Proper hygiene, handling, and storage are important when preparing infant feedings.

Do not add water.1. Pour LiquiProtein® into a medicine cup.2. Using a single use oral syringe, draw up volume specifi ed by a health

care professional.3. Dispense into measured human milk or formula and mix gently. Pour

desired amount of mixture into feeding container.

STORAGE• Store unopened at room temperature; avoid extreme temperatures. • Once opened, refrigerate and use within 72 hours.• When mixed with human milk or formula, cover and refrigerate unused

mixture immediately. Use within 24 hours or according to normal hospital procedure.

• For preterm infants who are tube-fed, fortifi ed milk can remain safely at room temperature (25°C) for up to 4 hours.2

ENERGYPer 6 mL Per 54 mL

ENERGY (Cal [kJ]) 4 (17) 35 (149)PROTEIN (g) 1 9% of total energy 100Source Casein hydrolysate

MINERALS††

Sodium (mg) 5 50Potassium (mg) 10 100

INGREDIENTSLiquiProtein®, Ready-to-mix liquid:Water, Casein hydrolysate (milk).Contains: Milk.

†† Other inherent minerals may be present in trace amounts.REFERENCES:1. Government of Canada. Preparing and handling powdered infant formula. Last modifi ed on 2021-04-16. [Accessed online on 2021-06-08]. 2. Steele C, Collins E (Editors). Infant and Pediatric Feedings: Guidelines for Preparation of Human Milk and Formula in Health Care Facilities, 3rd Ed. Academy of Nutrition and Dietetics. 2019. 3. Shakeel F, Newkirk M, Altoubah T et al. Nutr Clin Pract 2019;34(3):450-8.

Values listed are subject to change. Please refer to the product label or packaging for the most current ingredient, allergen and nutrient profi le information.

INGREDIENTS LISTAS PER COMMODITY #C4220-02

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SIMILAC® SPECIAL CARE® 20DHA- and ARA-enriched formulaFor preterm infants

INDICATIONS FOR USE• For infants who are born prematurely and have additional nutrient

needs that were not met in-utero.• Can be used as part of the Similac Liqui-MixTM System to prepare

customized feedings of various caloric densities.• Recommended until infant reaches 3600 g (approximately 8 lb).• For oral or tube feeding use.• Use under medical supervision.Safety precautions:• Not intended for feeding preterm infants after they reach a weight

of 3600 g, or as directed by a physician.• If signs of intolerance develop, slow feeding or discontinue.• Not for parenteral use.

FEATURES AND BENEFITS• Higher levels of protein, electrolytes, vitamins and minerals per

100 Cal than standard term formula.• Calcium and phosphorus at concentrations and ratio (1.8:1) that

support intrauterine accretion rates.1• Exclusive blend of DHA, lutein, and natural vitamin E:† - Results of a clinical study point to protective effects of lutein on preterm retinal health and maturation.2• Approximately 2 mg iron/kg body weight per day when fed at

120 Cal/kg/day.• 39% of fat as medium chain triglycerides.• Supports normal growth and bone mineralization in preterm infants

born at <33 weeks gestation.3• Improves early language‡ and visual development§ in preterm

infants.4¶

• Non-GMO.††

• Easy to digest.‡‡

TECHNICAL DATAReady to use

Caloric density (Cal/mL) 0.68Protein (% of total energy) 12.0 Fat (% of total energy) 46.8Carbohydrate (% of total energy) 41.2Total Cal:g nitrogen ratio 213:1Non-protein Cal:g nitrogen ratio 187:1

Water (g/L) 860Osmolality (mOsm/kg water) 238Renal solute load (mOsm/L) 190Minimum tube size for gravity/pump feeding (Fr)

N/A

Low residue YesGluten-free YesKosher Yes Halal Yes

AVAILABILITYReady to use66354871 Similac® Special Care® 20 59-mL plastic 48/case bottles

† RRR-a-tocopherol, provided as d-a-tocopheryl acetate, the most bioactive form of vitamin E.‡ Compared to infants fed Similac® Special Care® and Similac® Neosure® infant formulas without

DHA and ARA. § Visual acuity measured at 4 and 6 months corrected age and assessed by VEP (visual evoked

potential).¶ Based on a post-hoc analysis of English-speaking singleton premature infants using the MacArthur

Communicative Developmental Inventories.†† Ingredients not genetically engineered.‡‡ Similar to other infant formulas.REFERENCES:1. Mize CE, Uauy R, Waidelich D et al. Am J Clin Nutr 1995;62:385-91. 2. Rubin LP, Chan GM, Barrett-Reis BM et al. J Perinatol 2012;32(6):418-24. 3. Groh-Wargo S, Jacobs J, Auestad N et al. Pediatr Res 2005;57:712-8. 4. O'Connor DL, Hall R, Adamkin D et al. Pediatr 2001;108:359-71.

Exclusive blend of DHA, lutein, and natural vitamin E†

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SIMILAC® SPECIAL CARE® 20DHA- and ARA-enriched formulaFor preterm infants

ENERGYPer 100 mL Per 100 Cal

ENERGY (Cal [kJ]) 68 (283) 100 (418)PROTEIN (g) 2 3.00% of total energy 12.0 Taurine (mg) 4.2 6.2 Carnitine (mg) 3.8 5.6Nucleotides (mg) 7.2 10.7Source Dry or evaporated skim milk, whey protein concentrate FAT (g) 3.6 5.36% of total energy 46.8 Linoleic Acid (g) 0.47 0.700 Arachidonic Acid (ARA) (g) 0.017 0.025 Linolenic Acid (g) 0.057 0.084 Docosahexaenoic Acid (DHA) (g) 0.011 0.017 Omega-6:Omega-3 ratio 6.6:1Source MCT oil, soy oil, coconut oil,

high oleic sunfl ower oil, ARA and DHAMCT oil (% of total fats) 39.1CARBOHYDRATE (g) 6.9 10.3% of total energy 41.2 Total dietary fi bre (g) - - Short-chain fructooligosac-

charides (scFOS) (g)- -

Galactooligosaccharides (GOS) (g) - -Source Corn syrup solids, lactoseAcesulfame-potassium (mg) - -Sucralose (mg) - -

VITAMINSVitamin A (IU) 465 687Vitamin D (IU) 102 150Vitamin E (IU) 3.1 4.5Vitamin K (mg) 0.0081 0.012Vitamin C (mg) 9.5 14.0Thiamine (mg) 0.093 0.138Ribofl avin (mg) 0.13 0.192Niacin (mg) 0.54 0.800Vitamin B6 (mg) 0.078 0.115Folic acid (mg) 0.022 0.032Vitamin B12 (mg) 0.00016 0.00023Pantothenic acid (mg) 0.61 0.900Biotin (mg) 0.0019 0.0028Choline (mg) 8.1 12.0Inositol (mg) 9.7 14.4Lutein (mg) 0.014 0.021

MINERALSSodium (mg) 32 48Potassium (mg) 94 139Chloride (mg) 55 81Calcium (mg) 122 180Phosphorus (mg) 68 100Magnesium (mg) 6.4 9.5Iron (mg) 1.2 1.8Zinc (mg) 0.68 1.00Iodine (mg) 0.0073 0.0108Copper (mg) 0.068 0.100Manganese (mg) 0.0043 0.0063Selenium (mg) 0.0031 0.0045Chromium (mg) - -Molybdenum (mg) - -

INGREDIENTSSimilac® Special Care® 20, Ready to use:Water, Corn syrup solids, Dry or evaporated skim milk, Lactose, Modifi ed coconut and/or palm kernel oils (medium chain triglycerides), Whey protein concentrate, Soy oil, Coconut oil, High oleic sunfl ower oil, Calcium phosphate, Sodium citrate, Ascorbic acid, M. alpina oil (a source of ARA), C. cohnii oil (a source of DHA), Calcium carbonate, Soy lecithin, Monoglycerides, Carrageenan, Magnesium chloride, Potassium chloride, M-inositol, Potassium citrate, Potassium hydroxide, Ferrous sulphate, Taurine, Choline bitartrate, L-carnitine, Choline chloride, Cytidine 5'-monophosphate, D-alpha tocopheryl acetate, Zinc sulphate, Disodium guanosine 5'-monophosphate, Disodium uridine 5'-monophosphate, Adenosine 5'-monophosphate, Calcium D-pantothenate, Niacinamide, Vitamin A palmitate, Cupric sulphate, Ribofl avin, Thiamine chloride hydrochloride, Pyridoxine hydrochloride, Folic acid, Lutein, Beta-carotene, Phylloquinone, Manganese sulphate, Sodium selenite, Vitamin D3, Biotin, Cyanocobalamin. As needed: Sodium chloride, Potassium phosphate. Contains: Milk, Soy.

Values listed are subject to change. Please refer to the product label or packaging for the most current ingredient, allergen and nutrient profi le information.

INGREDIENTS LISTAS PER COMMODITY #C5873-01_15099

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SIMILAC® SPECIAL CARE® 24Hypercaloric, DHA- and ARA-enriched formulaFor preterm infants

INDICATIONS FOR USE• For infants who are born prematurely and have additional nutrient

needs that were not met in-utero.• Can be used as part of the Similac Liqui-MixTM System, to prepare customized feedings of various caloric densities.• Recommended until infant reaches 3600 g (approximately 8 lb).• For oral or tube feeding use.• Use under medical supervision.Safety precautions:• Not intended for feeding preterm infants after they reach a weight

of 3600 g, or as directed by a physician.• If signs of intolerance develop, slow feeding or discontinue.• Not for parenteral use.

FEATURES AND BENEFITS• Hypercaloric formula (81 Cal/100 mL [24 Cal/30 mL]) with higher levels of protein, electrolytes, vitamins, and minerals per 100 Cal than standard term formula.• Calcium and phosphorus at concentrations and ratio (1.8:1) that

support intrauterine accretion rates.1• Exclusive blend of DHA, lutein, and natural vitamin E:† - Results of a clinical study point to protective effects of lutein on preterm retinal health and maturation.2• Approximately 2 mg iron/kg body weight per day when fed at

120 Cal/kg/day.• 39% of fat as medium chain triglycerides.• Supports normal growth and bone mineralization in preterm infants born at <33 weeks gestation.3• Improves early language‡ and visual development§ in preterm infants.4¶

• Non-GMO.††

• Easy to digest.‡‡

TECHNICAL DATAReady to use

Caloric density (Cal/mL) 0.81Protein (% of total energy) 12.0Fat (% of total energy) 46.8Carbohydrate (% of total energy) 41.2 Total Cal:g nitrogen ratio 213:1Non-protein Cal:g nitrogen ratio 187:1

Water (g/L) 880Osmolality (mOsm/kg water) 300Renal solute load (mOsm/L) 227Minimum tube size for gravity/pump feeding (Fr)

N/A

Low residue YesGluten-free YesKosher Yes Halal Yes

AVAILABILITYReady to use66355871 Similac® Special Care® 24 59-mL plastic 48/case bottles

† RRR-a-tocopherol, provided as d-a-tocopheryl acetate, the most bioactive form of vitamin E.‡ Compared to infants fed Similac® Special Care® and Similac® Neosure® infant formulas without

DHA and ARA. § Visual acuity measured at 4 and 6 months corrected age and assessed by VEP (visual evoked

potential).¶ Based on a post-hoc analysis of English-speaking singleton premature infants using the MacArthur

Communicative Developmental Inventories.†† Ingredients not genetically engineered.‡‡ Similar to other infant formulas.REFERENCES:1. Mize CE, Uauy R, Waidelich D et al. Am J Clin Nutr 1995;62:385-91. 2. Rubin LP, Chan GM, Barrett-Reis BM et al. J Perinatol 2012;32(6):418-24. 3. Groh-Wargo S, Jacobs J, Auestad N et al. Pediatr Res 2005;57:712-8. 4. O'Connor DL, Hall R, Adamkin D et al. Pediatr 2001;108:359-71.

Exclusive blend of DHA, lutein, and natural vitamin E†

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SIMILAC® SPECIAL CARE® 24Hypercaloric, DHA- and ARA-enriched formulaFor preterm infants

ENERGYPer 100 mL Per 100 Cal

ENERGY (Cal [kJ]) 81 (340) 100 (418)PROTEIN (g) 2.4 3.00% of total energy 12.0 Taurine (mg) 5 6.2 Carnitine (mg) 4.5 5.6Nucleotides (mg) 7.2 8.9Source Dry or evaporated skim milk, whey protein concentrateFAT (g) 4.4 5.36% of total energy 46.8 Linoleic Acid (g) 0.57 0.700 Arachidonic Acid (ARA) (g) 0.02 0.025 Linolenic Acid (g) 0.068 0.084 Docosahexaenoic Acid (DHA) (g) 0.014 0.017 Omega-6:Omega-3 ratio 6.6:1Source MCT oil, soy oil, coconut oil,

high oleic sunfl ower oil, ARA and DHAMCT oil (% of total fats) 39.2CARBOHYDRATE (g) 8.4 10.3% of total energy 41.2 Total dietary fi bre (g) - - Short-chain fructooligosac-

charides (scFOS) (g)- -

Galactooligosaccharides (GOS) (g) - -Source Corn syrup solids, lactose Acesulfame-potassium (mg) - -Sucralose (mg) - -

VITAMINSVitamin A (IU) 558 687Vitamin D (IU) 122 150Vitamin E (IU) 3.7 4.5Vitamin K (mg) 0.0097 0.012Vitamin C (mg) 11 14.0Thiamine (mg) 0.11 0.138Ribofl avin (mg) 0.16 0.192Niacin (mg) 0.65 0.800Vitamin B6 (mg) 0.093 0.115Folic acid (mg) 0.026 0.032Vitamin B12 (mg) 0.00019 0.00023Pantothenic Acid (mg) 0.73 0.900Biotin (mg) 0.0023 0.0028Choline (mg) 9.7 12.0Inositol (mg) 11 14.4Lutein (mg) 0.014 0.017

MINERALSSodium (mg) 39 48Potassium (mg) 113 139Chloride (mg) 66 81Calcium (mg) 146 180Phosphorus (mg) 81 100Magnesium (mg) 7.7 9.5Iron (mg) 1.5 1.8Zinc (mg) 0.81 1.00Iodine (mg) 0.0088 0.0108Copper (mg) 0.081 0.100Manganese (mg) 0.0051 0.0063Selenium (mg) 0.0037 0.0045Chromium (mg) - -Molybdenum (mg) - -

INGREDIENTSSimilac® Special Care® 24, Ready to use:Water, Corn syrup solids, Dry or evaporated skim milk, Lactose, Modifi ed coconut and/or palm kernel oils (medium chain triglycerides), Whey protein concentrate, Soy oil, Coconut oil, High oleic sunfl ower oil, Calcium phosphate, Sodium citrate, Ascorbic acid, M. alpina oil (a source of ARA), C. cohnii oil (a source of DHA), Soy lecithin, Monoglycerides, Potassium chloride, Carrageenan, Magnesium chloride, M-inositol, Potassium citrate, Potassium hydroxide, Calcium carbonate, Ferrous sulphate, Taurine, Choline bitartrate, Choline chloride, L-carnitine, Cytidine 5'-monophosphate, D-alpha tocopheryl acetate, Zinc sulphate, Disodium guanosine 5'-monophosphate, Disodium uridine 5'-monophosphate, Adenosine 5'-monophosphate, Calcium D-pantothenate, Niacinamide, Vitamin A palmitate, Cupric sulphate, Ribofl avin, Thiamine chloride hydrochloride, Pyridoxine hydrochloride, Folic acid, Lutein, Phylloquinone, Beta-carotene, Manganese sulphate, Sodium selenite, Vitamin D3, Biotin, Cyanocobalamin. As needed: Sodium chloride, Potas sium phosphate. Contains: Milk, Soy.

Values listed are subject to change. Please refer to the product label or packaging for the most current ingredient, allergen and nutrient profi le information.

INGREDIENTS LISTAS PER COMMODITY #C5875-01 SEQ 15101

SEQ 14673

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SIMILAC® SPECIAL CARE® 24 HIGH PROTEIN High-protein, hypercaloric, DHA- and ARA-enriched formula For preterm infants

INDICATIONS FOR USE• For infants who are born prematurely and have additional nutrient

needs that were not met in-utero and who may need extra protein to help support growth.

• Can be used as part of the Similac Liqui-MixTM System to prepare customized feedings of various caloric densities.

• Recommended until infant reaches 3600 g (approximately 8 lb).• For oral or tube feeding use.• Use under medical supervision.Safety precautions:• Not intended for feeding preterm infants after they reach a weight

of 3600 g, or as directed by a physician. • Do not exceed a protein intake of: - 4.0-4.5 g/kg/day for infants up to 1000 g (3.6-4.1 g/100 Cal) - 3.5-4.0 g/kg/day for infants from 1000-1800 g (3.2-3.6 g/100 Cal)• If signs of intolerance develop, slow feeding or discontinue.• Not for parenteral use.FEATURES AND BENEFITS• Hypercaloric formula (81 Cal/100 mL [24 Cal/30 mL]) with higher

levels of protein, electrolytes, vitamins, and minerals per 100 Cal than standard term formula.

• Approximately 10% more protein than Similac® Special Care® 24 (3.3 g vs. 3.0 g/100 Cal).

• Calcium and phosphorus at concentrations and ratio (1.8:1) that support intrauterine accretion rates.1

• Exclusive blend of DHA, lutein, and natural vitamin E:† - Results of a clinical study point to protective effects of lutein on preterm retinal health and maturation.2 • Approximately 2 mg iron/kg body weight per day when fed at

120 Cal/kg/day.• 39% of fat as medium chain triglycerides.• Supports normal growth and bone mineralization in preterm infants

born at <33 weeks gestation.3• Improves early language‡ and visual development§ in preterm

infants.4¶

• Non-GMO.††

• Easy to digest.‡‡

TECHNICAL DATAReady to use

Caloric density (Cal/mL) 0.81Protein (% of total energy) 13.2Fat (% of total energy) 46.8Carbohydrate (% of total energy) 40.0Total Cal:g nitrogen ratio 193:1Non-protein Cal:g nitrogen ratio 168:1

Water (g/L) 830Osmolality (mOsm/kg water) 296Renal solute load (mOsm/L) 245Minimum tube size for gravity/pump feeding (Fr)

N/A

Low residue YesGluten-free YesKosher YesHalal Yes

AVAILABILITYReady to use66356871 Similac® Special Care® 24 59-mL 48/case High Protein plastic bottles

Exclusive blend of DHA, lutein, and natural vitamin E†

† RRR-a-tocopherol, provided as d-a-tocopheryl acetate, the most bioactive form of vitamin E.‡ Compared to infants fed Similac® Special Care® and Similac® Neosure® infant formulas without

DHA and ARA. § Visual acuity measured at 4 and 6 months corrected age and assessed by VEP (visual evoked

potential).¶ Based on a post-hoc analysis of English-speaking singleton premature infants using the MacArthur

Communicative Developmental Inventories.†† Ingredients not genetically engineered.‡‡ Similar to other infant formulas.

REFERENCES: 1. Mize CE, Uauy R, Waidelich D et al. Am J Clin Nutr. 1995;62:385-91. 2. Rubin LP, Chan GM, Barrett-Reis BM et al. J Perinatol 2012;32(6):418-24. 3. Groh-Wargo S, Jacobs J, Auestad N et al. Pediatr Res 2005;57:712-8. 4. O'Connor DL, Hall R, Adamkin D et al. Pediatr 2001;108:359-71.

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SIMILAC® SPECIAL CARE® 24 HIGH PROTEIN High-protein, hypercaloric, DHA- and ARA-enriched formulaFor preterm infants

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Per 100 mL Per 100 CalENERGY (Cal [kJ]) 81 (340) 100 (418)PROTEIN (g) 2.7 3.30% of total energy 13.2 Taurine (mg) 5 6.2 Carnitine (mg) 4.5 5.6Nucleotides (mg) 7.2 8.9Source Dry or evaporated skim milk, whey protein concentrateFAT (g) 4.4 5.36% of total energy 46.8 Linoleic acid (g) 0.57 0.700 Arachidonic acid (ARA) (g) 0.02 0.025 Linolenic acid (g) 0.068 0.084 Docosahexaenoic acid (DHA) (g) 0.014 0.017 Omega-6:Omega-3 ratio 6.4:1Source MCT oil, soy oil, coconut oil, high oleic sunfl ower oil,

ARA and DHAMCT oil (% of total fats) 39.3CARBOHYDRATE (g) 8.1 10.00% of total energy 40.0 Total dietary fi bre (g) - - Short-chain fructooligosac-

charides (scFOS) (g)- -

Galactooligosaccharides (GOS) (g) - -Source Corn syrup solids, lactoseAcesulfame-potassium (mg) - -Sucralose (mg) - -

VITAMINSVitamin A (IU) 558 687Vitamin D (IU) 122 150Vitamin E (IU) 3.7 4.5Vitamin K (mg) 0.0097 0.012Vitamin C (mg) 11 14.0Thiamine (mg) 0.11 0.138Ribofl avin (mg) 0.16 0.192Niacin (mg) 0.65 0.800Vitamin B6 (mg) 0.093 0.115Folic acid (mg) 0.026 0.032Vitamin B12 (mg) 0.00019 0.00023Pantothenic acid (mg) 0.73 0.900Biotin (mg) 0.0023 0.0028Choline (mg) 9.7 12.0Inositol (mg) 11.7 14.4Lutein (mg) 0.014 0.017

MINERALSSodium (mg) 39 48Potassium (mg) 118 146Chloride (mg) 66 81Calcium (mg) 146 180Phosphorus (mg) 81 100Magnesium (mg) 7.7 9.5Iron (mg) 1.5 1.8Zinc (mg) 0.81 1.00Iodine (mg) 0.0088 0.0108Copper (mg) 0.081 0.100Manganese (mg) 0.0051 0.0063Selenium (mg) 0.0037 0.0045Chromium (mg) - -Molybdenum (mg) - -

INGREDIENTSSimilac® Special Care® 24 High Protein, Ready to use:Water, Corn syrup solids, Dry or evaporated skim milk, Lactose, Whey protein concentrate, Modifi ed coconut and/or palm kernel oils (medium chain triglycerides), Soy oil, Coconut oil, High oleic sunfl ower oil, Calcium phosphate, Sodium citrate, Ascorbic acid, M. alpina oil (a source of ARA), C. cohnii oil (a source of DHA), Soy lecithin, Monoglycerides, Carrageenan, Potassium citrate, Magnesium chloride, M-inositol, Potassium chloride, Calcium carbonate, Potassium hydroxide, Ferrous sulphate, Taurine, Choline bitartrate, Choline chloride, L-carnitine, Cytidine 5'-monophosphate, D-alpha tocopheryl acetate, Zinc sulphate, Disodium guanosine 5'-monophosphate, Disodium uridine 5'-monophosphate, Adenosine 5'-monophosphate, Calcium D-pantothenate, Niacinamide, Vitamin A palmitate, Cupric sulphate, Ribofl avin,Thiamine hydrochloride, Pyridoxine hydrochloride, Folic acid, Lutein, Phylloquinone, Beta-carotene, Manganese sulphate, Sodium selenite, Vitamin D3, Biotin, Cyanocobalamin. As needed: Sodium chloride, Potassium phosphate. Contains: Milk, Soy.

Values listed are subject to change. Please refer to the product label or packaging for the most current ingredient, allergen and nutrient profi le information.

INGREDIENTS LISTAS PER COMMODITY #C5877-01

SEQ 15103

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SIMILAC® NEOSURE®

DHA- and ARA-enriched formulaFor preterm infants 0 to 12 months corrected age

INDICATIONS FOR USE• For use as a breast milk substitute in preterm infants being discharged home.• For breastfed preterm infants; supplementing with feedings of prepared post-

discharge formula is recommended as a strategy for meeting additional nutrient requirements.1

• Term infant formula (such as Similac Pro-Advance®) can be introduced at the discretion of the health care professional once the baby has achieved adequate catch-up growth. Some recommendations include:

- The use of a post-discharge formula should be “individualized to optimize the growth trajectory of the infant over the fi rst year”;1

- Use from 40 to 52 weeks post-conception;2 - Stopping at 4 to 6 months corrected age if all growth parameters

are >25th percentile.3• For oral or tube feeding use.• Use under medical supervision.Safety precaution:• Not for parenteral use.

FEATURES AND BENEFITS• 74 Cal/100 mL (22 Cal/30 mL).• Supports catch-up growth during the fi rst year:4 - Increased calories for growth. - 33% more protein† to help meet higher protein requirements. - Approximately 35% more calcium and phosphorus† to support the

baby’s growing bones.• Peer-reviewed studies evaluating the use of preterm post-discharge formula compared to term infant formula in preterm infants have demonstrated: - Greater gains in weight, length, and head circumference compared to those

fed term formula.‡ - An increase in lean body mass rather than fat mass.5,6

• DHA, the most abundant Omega-3 fatty acid in the brain and eyes.7• Approximately 25% of fat as medium chain triglycerides, an easily digested and well-absorbed fat source.8• Easy to digest.§

TECHNICAL DATAPowder

(at standard dilution)Caloric density (Cal/mL) 0.74Protein (% of total energy) 11Fat (% of total energy) 49Carbohydrate (% of total energy) 40Total Cal:g nitrogen ratio 228:1Non-protein Cal:g nitrogen ratio 203:1

Water (g/L) 890Osmolality (mOsm/kg water) 250Renal solute load (mOsm/L) 187Minimum tube size for gravity/pump feeding (Fr)

N/A

Low residue YesGluten-free YesKosher YesHalal Yes

AVAILABILITYPowder57430718 Similac® Neosure® 363-g cans 6/case

† Compared to Similac Pro-Advance® (per 100 Cal). ‡ Similac® Neosure® formulation used in this study may differ slightly from current Similac® Neosure®

product. § Similar to other infant formulas.REFERENCES:1. American Academy of Pediatrics Committee on Nutrition. Nutritional Needs of the Preterm Infant. In: Kleinman RE, Greer FR, eds. Pediatric Nutrition. 7th ed. Elk Grove Village, IL: American Academy of Pediatrics; 2014:109-11. 2. ESPGHAN Committee on Nutrition. J Pediatr Gastroenterol Nutr 2006;42:596-603. 3. Bhatia J. J Perinatol 2005;25(suppl 2):S15-S16. 4. Carver JD, Wu PYK, Hall RT et al. Pediatrics 2001;107:683-9. 5. Cooke RJ, Griffi n IJ, McCormick K. Pediatr Res 2010;67:660-4. 6. Lucas A, Fewtrell MS, Morley R et al. Pediatrics 2001;108:703-11. 7. Calder PC. Docosahexaenoic Acid. Ann Nutr Metab 2016;69(Suppl. 1):8-21. 8. Duggan C, Watkins JB, Walker WA. BC Decker Inc. Hamilton. 2008.

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SIMILAC® NEOSURE®

DHA- and ARA-enriched formulaFor preterm infants 0 to12 months corrected age

PREPARATIONThe health of the infant depends on carefully following the directions for preparation and use. Proper hygiene, handling and storage are important when preparing infant feedings. Similac® Neosure® Powder Mixing Chart

Caloric Density(Cal/30 mL)

Unpacked, level scoops¶

Water(mL)

Approximate Yield†† (mL)

20 2 135 150 22 (standard) 1 60 67

24 3 165 17727 5 240 277

ENERGY

Per 100 g Powder

Per 100 mL(at standard

dilution) Per 100 CalENERGY (Cal [kJ]) 513 (2146) 74 (310) 100 (418)PROTEIN (g) 15 2.1 2.8% of total energy 11 Taurine (mg) 48 7.0 9.41 Carnitine (mg) 33 4.8 6.45Nucleotides (mg) 50 7.2 9.6Source Skim milk, whey protein concentrate,

whey protein hydrolysateFAT (g) 28 4.1 5.5% of total energy 49 Linoleic Acid (g) 4.1 0.60 0.805 Arachidonic Acid (ARA) (g) 0.1 0.015 0.020 Linolenic Acid (g) 0.53 0.08 0.104 Docosahexaenoic Acid (DHA) (g) 0.064 0.009 0.013 Omega-6:Omega-3 ratio 8.24:1Source Soy oil, high oleic saffl ower oil, MCT oil, coconut oil,

M. alpina oil, C. cohnii oilMCT oil (% of total fats) 24.9CARBOHYDRATE (g) 52 7.5 10.1% of total energy 40 Total dietary fi bre (g) - - - Short-chain fructooligosac-

charides (scFOS) (g)- - -

Galactooligosaccharides (GOS) (g) - - -Source Corn syrup solids, lactoseAcesulfame-potassium (mg) - - -Sucralose (mg) - - -

VITAMINSVitamin A (IU) 2367 343 461Vitamin D (IU) 359 52 70Vitamin E (IU) 19 2.7 3.6Vitamin K (mg) 0.055 0.008 0.011Vitamin C (mg) 76 11 15Thiamine (mg) 1.13 0.16 0.22Ribofl avin (mg) 0.77 0.11 0.151Niacin (mg) 10.1 1.5 1.96Vitamin B6 (mg) 0.51 0.074 0.10Folic acid (mg) 0.13 0.019 0.026Vitamin B12 (mg) 0.0021 0.0003 0.00041Pantothenic acid (mg) 4.1 0.59 0.80Biotin (mg) 0.046 0.007 0.009Choline (mg) 83 12 16Inositol (mg) 179 26 35

MINERALSSodium (mg) 173 25 33Potassium (mg) 732 106 143Chloride (mg) 386 56 75Calcium (mg) 538 78 105Phosphorus (mg) 317 46 62Magnesium (mg) 48 7 9Iron (mg) 9 1.3 1.8Zinc (mg) 6.2 0.9 1.2Iodine (mg) 0.076 0.011 0.015Copper (mg) 0.61 0.09 0.120Manganese (mg) 0.051 0.0074 0.010Selenium (mg) 0.012 0.0017 0.0023Chromium (mg) - - -Molybdenum (mg) - - -

INGREDIENTSSimilac® Neosure®, Powder: Dry skim milk, Corn syrup solids, Lactose, Soy oil, High oleic saffl ower oil, Modifi ed coconut and/or palm kernel oils (medium chain triglycerides), Whey protein concentrate, Coconut oil, Whey protein hydrolysate, Calcium phosphate, Ascorbic acid, M. alpina oil (a source of ARA), Calcium carbonate, M-inositol, C. cohnii oil (a source of DHA), Potassium citrate, Magnesium chloride, Potassium chloride, Taurine, Ferrous sulphate, Choline bitartrate, Choline chloride, L-carnitine, Ascorbyl palmitate, Cytidine 5'-monophosphate, D-alpha-tocopheryl acetate, Disodium guanosine 5'-monophosphate, Zinc sulphate, Disodium uridine 5'-monophosphate, Niacinamide, Adenosine 5'-monophosphate, Mixed tocopherols, Calcium d-pantothenate, Cupric sulphate, Thiamine hydrochloride, Vitamin A palmitate, Ribofl avin, Pyridoxine hydrochloride, Beta-carotene, Folic acid, Manganese sulphate, Phylloquinone, Biotin, Sodium selenate, Vitamin D3, Cyanocobalamin. As needed: Sodium chloride, Sodium citrate, Potassium hydroxide. Contains: Milk.

Values listed are subject to change. Please refer to the product label or packaging for the most current ingredient, allergen and nutrient profi le information.

¶ Use only scoop provided in the container.†† Calculated using displacement volume and rounded to the nearest whole number.

INGREDIENTS LISTAS PER COMMODITY #C5823-06

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SIMILAC® NEOSURE®

DHA- and ARA-enriched formulaFor preterm infants 0 to12 months corrected age

INDICATIONS FOR USE• For use as a breast milk substitute in preterm infants being

discharged home.• For breastfed preterm infants; supplementing with feedings of

prepared post-discharge formula is recommended as a strategy for meeting additional nutrient requirements.1

• Term infant formula (such as Similac Pro-Advance®) can be introduced at the discretion of the health care professional once the baby has achieved adequate catch-up growth. Some recommendations include: - The use of a post-discharge formula should be “individualized to optimize the growth trajectory of the infant over the fi rst year”;1 - Use from 40 to 52 weeks post-conception;2 - Stopping at 4 to 6 months corrected age if all growth parameters are >25th percentile.3• For oral or tube feeding use.• Use under medical supervision.Safety precaution:• Not for parenteral use.FEATURES AND BENEFITS• Hypercaloric (74 Cal/100 mL [22 Cal/30 mL]) with higher levels

of protein, electrolytes, vitamins, and minerals per 100 Cal than standard term formula.

• Exclusive blend of DHA, lutein, and natural vitamin E:† - Results of a clinical study point to protective effects of lutein on preterm retinal health and maturation.4• Supports catch-up growth during the fi rst year:5 - Increased calories for growth. - 33% more protein‡ to help meet higher protein requirements. - Approximately 35% more calcium and phosphorus‡ to support the

baby’s growing bones.• Peer-reviewed studies evaluating the use of preterm post-discharge

formula compared to term infant formula in preterm infants have demonstrated:

- Greater gains in weight, length, and head circumferencecompared to those fed term formula.§

- An increase in lean body mass rather than fat mass.6,7

• Approximately 25% of fat as medium chain triglycerides, an easily digested and well-absorbed fat source.8

• Non-GMO.¶• Easy to digest.††

TECHNICAL DATAReady to use

Caloric density (Cal/mL) 0.74Protein (% of total energy) 11.2Fat (% of total energy) 48.5Carbohydrate (% of total energy) 40.3Total Cal:g nitrogen ratio 226:1Non-protein Cal:g nitrogen ratio 200:1

Water (g/L) 840Osmolality (mOsm/kg water) 250Renal solute load (mOsm/L) 188Minimum tube size for gravity/pump feeding (Fr)

N/A

Low residue YesGluten-free YesKosher YesHalal Yes

AVAILABILITYReady to use66358871 Similac® Neosure® 59-mL plastic 48/case bottles

† RRR-a-tocopherol, provided as d-a-tocopheryl acetate, the most bioactive form of vitamin E.‡ Compared to Similac ProAdvance® (per 100 Cal). § Formulation used in this study may differ slightly from current Similac® Neosure® product. ¶ Ingredients not genetically engineered.†† Similar to other infant formulas.REFERENCES:1. American Academy of Pediatrics Committee on Nutrition. Nutritional Needs of the Preterm Infant. In: Kleinman RE, Greer FR (eds). Pediatric Nutrition. 7th ed. Elk Grove Village, IL: American Academy of Pediatrics; 2014:109-11. 2. ESP-GHAN Committee on Nutrition. J Pediatr Gastroenterol Nutr 2006;42:596-603. 3. Bhatia J. J Perinatol 2005;25(suppl 2):S15-S16. 4. Rubin LP, Chan GM, Barrett-Reis BM et al. J Perinatol 2012;32(6):418-24. 5. Carver JD, Wu PYK, Hall RT et al. Pediatrics 2001;107:683-9. 6. Cooke RJ, Griffi n IJ, McCormick K. Pediatr Res 2010;67:660-4. 7. Lucas A, Fewtrell MS, Morley R et al. Pediatrics 2001;108:703-11. 8. Duggan C, Watkins JB, Walker WA. BC Decker Inc. Hamilton. 2008.

Exclusive blend of DHA, lutein, and natural vitamin E†

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SIMILAC® NEOSURE®

DHA- and ARA-enriched formulaFor preterm infants 0 to12 months corrected age

ENERGYPer 100 mL Per 100 Cal

ENERGY (Cal [kJ]) 74 (311) 100 (418)PROTEIN (g) 2.1 2.8% of total energy 11.2 Taurine (mg) 4.5 6.0 Carnitine (mg) 4.0 5.4Nucleotides (mg) 7.2 9.7Source Dry or evaporated skim milk, whey protein concentrateFAT (g) 4.1 5.5% of total energy 48.5 Linoleic Acid (g) 0.558 0.750 Arachidonic Acid (ARA) (g) 0.019 0.025 Linolenic Acid (g) 0.074 0.100 Docosahexaenoic Acid (DHA) (g) 0.013 0.017 Omega-6:Omega-3 ratio 6.4:1Source Soy oil, coconut oil, MCT oil, ARA and DHAMCT oil (% of total fats) 24.3CARBOHYDRATE (g) 7.5 10.1% of total energy 40.3 Total dietary fi bre (g) - - Short-chain fructooligosac-

charides (scFOS) (g)- -

Galactooligosaccharides (GOS) (g) - -Source Corn syrup solids, lactoseAcesulfame-potassium (mg) - -Sucralose (mg) - -

VITAMINSVitamin A (IU) 342 460Vitamin D (IU) 52 70Vitamin E (IU) 2.7 3.6 Vitamin K (mg) 0.0083 0.011Vitamin C (mg) 11 15Thiamine (mg) 0.164 0.220Ribofl avin (mg) 0.112 0.150Niacin (mg) 1.45 1.95Vitamin B6 (mg) 0.074 0.100Folic acid (mg) 0.019 0.025Vitamin B12 (mg) 0.0003 0.0004Pantothenic acid (mg) 0.60 0.80Biotin (mg) 0.007 0.009Choline (mg) 12 16Inositol (mg) 26 35Lutein (mg) 0.0115 0.0155

MINERALSSodium (mg) 25 33Potassium (mg) 112 150Chloride (mg) 56 75Calcium (mg) 78 105Phosphorus (mg) 46 62Magnesium (mg) 7 9Iron (mg) 1.3 1.8Zinc (mg) 0.89 1.2Iodine (mg) 0.011 0.015Copper (mg) 0.089 0.12Manganese (mg) 0.007 0.010Selenium (mg) 0.0016 0.0021Chromium (mg) - -Molybdenum (mg) - -

INGREDIENTSSimilac® Neosure®, Ready to use:Water, Corn syrup solids, Dry or evaporated skim milk, Soy oil, Lactose, Coconut oil, Whey protein concentrate, Modifi ed coconut and/or palm kernel oils (medium chain triglycerides), Potassium citrate, Ascorbic acid, Calcium carbonate, M. alpina oil (a source of ARA), C. cohnii oil (a source of DHA), Monoglycerides, Soy lecithin, M-inositol, Magnesium chloride, Potassium hydroxide, Calcium phosphate, Sodium chloride, Carrageenan, Taurine, Choline chloride, Ferrous sulphate, Choline bitartrate, L-carnitine, Cytidine 5'-monophosphate, Zinc sulphate, D-alpha tocopheryl acetate, Niacinamide, Disodium guanosine 5'-monophosphate, Disodium uridine 5'-monophosphate, Adenosine 5'-monophosphate, Calcium D-pantothenate, Cupric sulphate, Vitamin A palmitate, Thiamine chloride hydrochloride, Ribofl avin, Pyridoxine hydrochloride, Folic acid, Manganese sulphate, Lutein, Phylloquinone, Beta-carotene, Biotin, Sodium selenate, Potassium iodide, Vitamin D3, Cyanocobalamin. As needed: Potassium chloride, Potassium phosphate. Contains: Milk, Soy.

Values listed are subject to change. Please refer to the product label or packaging for the most current ingredient, allergen and nutrient profi le information.

INGREDIENTS LISTAS PER COMMODITY

#C6039-01_15043

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NOTES:

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Term Infants

Continued on next page

TERM INFANTSIN THIS SECTIONSimilac Pro-Advance® Step 1, powderSimilac Pro-Advance® Step 1Similac Pro-Advance® Step 2Similac® Advance® Step 1, powderSimilac® Advance® Step 1 Similac® Advance® Step 2Similac® Step 1 Similac® Step 2 Similac® Lower Iron

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Term

Infa

nts

TERM INFANTSIN THIS SECTION (continued)Similac Total Comfort®

Similac® Sensitive® Lactose SensitivitySimilac® Sensitive® Lactose Sensitivity (HFS)Similac® Isomil®

Similac® Isomil® (HFS)Similac® 24 (HFS)Similac® Alimentum® Similac® Alimentum® (RTU)Similac® Alimentum® (HFS)

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BREAST MILK –INSPIRING OUR RESEARCH AND INNOVATION

* Not derived from human milk; identical structure to 2’-FL found in breast milk.† RRR-a-tocopherol, provided as d-a-tocopheryl acetate, the most bioactive form of vitamin E.‡ With the exception of Similac® Alimentum®.REFERENCES: 1. Health Canada, Canadian Paediatric Society, Dietitians of Canada, and Breastfeeding Committee for Canada (2015). Nutrition for healthy term infants: Recommendations from birth to six months. Cited July 2020. 2. Field CJ. J Nutr 2005;135(1):1-4. 3. Iyengar SR, Walker WA. J Pediatr Gastroenterol Nutr 2012;55(6):641-7. 4. Gregory KE, Walker WA. Curr Pediatr Rep 2013 Dec;1(4):10. 5. Palmeira P, Carneiro-Sampaio M. 2016;62(6):584-93. 6. Jantscher-Krenn E, Bode L. Minerva Pediatr 2012;64:83-99. 7. Zivkovic AM, German JB, Lebrilla CB et al. Proc Natl Acad Sci 2011;108(Suppl 1):4653-8. 8. Castanys-Munoz E, Martin MJ, Prieto PA. Nutr Rev 2013;71(12):773-89. 9. Vishwanathan R, Kuchan MJ, Senet S et al. JPGN 2014;59(5);659-65. 10. Kuchan MJ, Jensen SK, Johnson EJ et al. Br J Nutr 2016;116:126-31. 11. Sherwood L. Human Physiology: From Cells to Systems, 7th ed. Brooks/Cole Cengage Learning 2010. 12. Wassall SR, Stillwell W. Biochim Biophys Acta 2009;1788:24-32.

Breast milk is the best way parents can promote their newborn's health and development. For babies that are not breastfed or receiving breast milk, Health Canada recommends commercial infant formula as the only safe and suitable alternative.1

When it comes to infant formula, breast milk inspires all our research and product innovation.

Breast milk contains protective immune factors, including human milk oligosaccharides (HMOs) like 2’-FL, that help build baby’s developing immune system.2-6 2’-FL is the most abundant HMO in breast milk and is found in the milk of most mothers.7,8 2’-FL Oligosaccharide,* a new and innovative ingredient that is structurally identical to 2’-FL in breast milk, is now available to formula-fed babies who are nourished with Similac Pro-Advance®.

Similac Pro-Advance®, the newest addition to the Similac® family, is our most advanced formula and the first formula with 2’-FL* in Canada.

Driven by our growing understanding of human milk, the following Similac® products contain an exclusive blend of DHA, lutein, and natural vitamin E.† These nutrients are found together in areas of the brain associated with memory and learning.9-12

• Similac Pro-Advance®

• Similac® Advance®

• Similac® HFS term‡ and preterm infant formulas

• Similac® Human Milk Fortifier Extensively Hydrolyzed Protein Concentrated Liquid

• Similac® Human Milk Fortifier Special Care® 30

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SIMILAC PRO-ADVANCE® STEP 1With 2’-FL oligosaccharide/DHA- and ARA-fortifi ed For term infants 0+ months of age

INDICATIONS FOR USE• For use as a breast milk substitute in infants who are not exclusively breastfed. • For oral or tube feeding use. Safety precaution: • Not for parenteral use. FEATURES AND BENEFITS• 2’-FL oligosaccharide is biosynthesized and structurally identical

to 2’-FL human milk oligosaccharide (HMO),1 the most abundant HMO found in the breast milk of most mothers.2 HMOs help support the breastfed baby’s developing immune system.3

• Similac® with 2’-FL* has been shown to support normal growth and is well tolerated by infants.4,5

• Addition of 2’-FL* to infant formula may help support the development and regulation of the formula-fed baby’s immune response to be closer to that of breastfed infants.6†

• DHA, the most abundant Omega-3 fatty acid in the brain and eyes.7

• Lutein, an antioxidant found in breast milk and concentrated in the infant brain and eyes.8-10

- Recent studies show that lutein may have a role in visual and cognitive development.11

• Vitamin E, a dietary antioxidant that protects fats in body tissues, like DHA, from oxidation.12

- Similac Pro-Advance® uses natural vitamin E,‡ the most abundant form found in breast milk and in the infant brain.13-16

• Non-GMO.§ • Easy to digest.¥ • Gluten-free.• Kosher.• Halal.TECHNICAL DATA

Powder(at standard dilution)

Caloric density (Cal/mL) 0.68Protein (% of total energy) 8.2Protein source Dry or evaporated skim milk, whey protein concentrate,

whey protein hydrolysateFat (% of total energy) 48.8Omega-6:Omega-3 ratio 9.7:1MCT oil (% of total fats) 0Fat source High oleic saffl ower oil, soy oil, coconut oil,

M. alpina oil, C. cohnii oil, soy lecithinCarbohydrate (% of total energy) 43.0Carbohydrate source Lactose, fructooligosaccharides, 2’-fucosyllactoseTotal Cal:g nitrogen ratio 309:1Non-protein Cal:g nitrogen ratio 284:1

Water (g/L) 904Osmolality (mOsm/kg water) 303Renal solute load (mOsm/L) 97Minimum tube size for gravity/pump feeding (Fr)

N/A

AVAILABILITYPowder 6720130B Similac Pro-Advance® Step 1 658-g container 6/case67208356 Similac Pro-Advance® Step 1 964-g container 6/case

2’-FL in breast milk helpsbuild the baby’s immune

system. Our most advanced formula contains 2’-FL.*

* Not derived from human milk; identical structure to 2'-FL found in breast milk.† Breast milk is best for babies, contains many immune factors not available in infant formula,

and its use is recommended for as long as possible during infancy.‡ RRR-a-tocopherol, provided as d-a-tocopheryl acetate, the most bioactive form of vitamin E. § Ingredients not genetically engineered. ¥ Similar to other infant formulas.

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SIMILAC PRO-ADVANCE® STEP 1With 2’-FL oligosaccharide/DHA- and ARA-fortifi ed For term infants 0+ months of age

ENERGY

Per 100 g Powder

Per 100 mL(at standard

dilution) Per 100 CalENERGY (Cal [kJ]) 516 (2160) 68 (280) 100 (418)PROTEIN (g) 11 1.4 2.1 Tryptophan (mg) 183 24 35 Taurine (mg) 35 4.5 6.7 Carnitine (mg) 7.6 0.99 1.5Nucleotides (mg) 55 7.2 10.7FAT (g) 29 3.7 5.5 Linoleic Acid (g) 4.0 0.53 0.78 Linolenic Acid (g) 0.38 0.050 0.075 Arachidonic Acid (ARA) (g) 0.11 0.014 0.0210 Docosahexaenoic Acid (DHA) (g) 0.055 0.0072 0.011CARBOHYDRATE (g) 56 7.3 10.8 Fibre (g) 1.4 0.18 0.27 2’-fucosyllactose (2’-FL) (mg) 153 20 30

VITAMINSVitamin A (IU) 1454 190 282Vitamin D (IU) 309 40 60Vitamin E (IU) 21 2.7 4.0Vitamin K (mg) 0.069 0.0090 0.0134Vitamin C (mg) 77 10 15Thiamine (mg) 0.61 0.080 0.12Ribofl avin (mg) 0.81 0.11 0.16Niacin (mg) 5.5 0.72 1.06Pantothenic acid (mg) 2.3 0.30 0.5Vitamin B6 (mg) 0.31 0.041 0.06Folic acid (mg) 0.053 0.0069 0.010Vitamin B12 (mg) 0.0013 0.00017 0.00026Biotin (mg) 0.019 0.0025 0.0037Choline (mg) 77 10 15Inositol (mg) 30 4.0 5.9Lutein (mg) 0.058 0.0076 0.011

MINERALSSodium (mg) 137 18 27Potassium (mg) 609 80 118Chloride (mg) 338 44 65Calcium (mg) 406 53 79Phosphorus (mg) 219 29 42Magnesium (mg) 40 5.2 7.7Iron (mg) 9.2 1.2 1.8Zinc (mg) 3.9 0.50 0.75Iodine (mg) 0.10 0.013 0.020Copper (mg) 0.41 0.053 0.079Manganese (mg) 0.037 0.0048 0.0071Selenium (mg) 0.010 0.0013 0.0020Chromium (mg) 0 0 0Molybdenum (mg) 0 0 0

INGREDIENTSSimilac Pro-Advance® Step 1, Powder: Lactose, Dry or evaporated skim milk, High oleic saffl ower oil, Soy oil, Coconut oil, Whey protein concentrate, Fructooligosaccharides, Whey protein hydrolysate, M. alpina oil (source of ARA), 2’-fucosyllactose, C. cohnii oil (source of DHA), Soy lecithin, L-tryptophan, Taurine, M-inositol, Cytidine 5’-monophosphate, Ascorbyl palmitate, Disodium guanosine 5’-monophosphate, Disodium uridine 5’-monophosphate, Adenosine 5’-monophosphate, L-carnitine, Mixed tocopherols, Lutein, Minerals (potassium citrate, calcium carbonate, tricalcium phosphate, potassium hydroxide, magnesium chloride, salt, ferrous sulphate, zinc sulphate, cupric sulphate, potassium chloride, manganese sulphate, sodium selenite, potassium iodide), Vitamins (ascorbic acid, choline bitartrate, D-alpha tocopheryl acetate, niacinamide, calcium D-pantothenate, vitamin A palmitate, thiamine hydrochloride, ribofl avin, pyridoxine hydrochloride, folic acid, beta-carotene, phylloquinone, D-biotin, vitamin D3, cyanocobalamin). Contains: Milk, Soy.

Values listed are subject to change. Please refer to the product label or packaging for the most current ingredient, allergen and nutrient profi le information.

REFERENCES: 1. Weichert S et al. Nutr Res 2013;3(10):831-8. 2. Castanys-Muñoz E et al. Nutr Rev 2013;71(12):773-89. 3. Jantscher-Krenn E, Bode L. Human Milk Oligosaccharides: Role in Infant Health. Nutrition in Infancy (9781627032230) [Internet]. 2013 Jan [cited 2020 Mar 18];209. 4. Marriage B et al. JPGN 2015;61:649-53. 5. Kajzer J et al. FASEB J 2016;30(Suppl. 1):671.4. 6. Goehring KC et al. J Nutr 2016;146(12):2559-66. 7. Calder PC. Ann Nutr Metab 2016;69(Suppl. 1):8-21. 8. Zimmer JP et al. Clin Ophtalmol 2007;1:25-35. 9. Krinsky NI et al. Ann Rev Nutr 2003;23:171-201. 10. Vishwanathan R et al. JPGN 2014;59(5);659-65. 11. Johnson EJ. Nutrition Reviews 2014;72(9):605-12. 12. Canadian Food Inspection Agency: Health Claims - Nutrient Function Claims. Last modifi ed on 2019-10-31. [Accessed online on 2020-07-17]. 13. Stone WL et al. Am J Clin Nutr 2003;77:899-906. 14. Institute of Medicine. Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium and Carotenoids. National Academy of Sciences. 2000. 15. Kuchan MJ et al. Curr Dev Nutr 2018;2:nzy055. 16. Kuchan MJ et al. Br J Nutr 2016;116:126-31.

Page 54: 2021 PEDIATRIC NUTRITIONAL PRODUCTS GUIDE

INDICATIONS FOR USE• For use as a breast milk substitute in infants who are not exclusively breastfed. • For oral or tube feeding use. Safety precaution: • Not for parenteral use.

FEATURES AND BENEFITS• 2’-FL oligosaccharide is biosynthesized and structurally identical to 2’-FL

human milk oligosaccharide (HMO),1 the most abundant HMO found in the breast milk of most mothers.2 HMOs help support the breastfed baby’s developing immune system.3

• Similac® with 2’-FL* has been shown to support normal growth and is well tolerated by infants.4,5

• Addition of 2’-FL* to infant formula may help support the development and regulation of the formula-fed baby’s immune response to be closer to that of breastfed infants.6†

• DHA, an Omega-3 fatty acid that supports the normal physical development of the brain and eyes.7

• Lutein, an antioxidant found in breast milk and concentrated in the infant brain and eyes.8-10

- Recent studies show that lutein may have a role in visual and cognitive development.11

• Vitamin E, a dietary antioxidant that protects fats in body tissues, like DHA, from oxidation.7

- Similac Pro-Advance® uses natural vitamin E,‡ the most abundant form found in breast milk and in the infant brain.12-15

• Non-GMO.§ • Easy to digest.¥• Gluten-free.• Kosher.• Halal.

TECHNICAL DATAReady to use

Caloric density (Cal/mL) 0.68Protein (% of total energy) 8.3Protein source Dry or evaporated skim milk, whey protein

concentrateFat (% of total energy) 49.3Omega-6:Omega-3 ratio 8.12:1MCT oil (% of total fats) 0Fat source High oleic saffl ower oil, soy oil, coconut oil,

M. alpina oil, C. cohnii oil, monoglycerides, soy lecithin

Carbohydrate (% of total energy) 42.4Carbohydrate source Lactose, fructooligosaccharides,

2’-fucosyllactoseTotal Cal:g nitrogen ratio 304:1Non-protein Cal:g nitrogen ratio 277:1

Water (g/L) 904Osmolality (mOsm/kg water) 306Renal solute load (mOsm/L) 127Minimum tube size for gravity/pump feeding (Fr)

N/A

AVAILABILITYReady to use(Institutional/Hospital)67269871 Similac Pro-Advance® Step 1 6 x 59-mL plastic bottles 8/case with Nipple & Ring(Retail)67271A71 Similac Pro-Advance® Step 1 24 x 59-mL plastic bottles 4/case67269871 Similac Pro-Advance® Step 1 6 x 59-mL plastic bottles 8/case with Nipple & Ring67267899 Similac Pro-Advance® Step 1 235-mL plastic bottles 16/case67856825 Similac Pro-Advance® Step 1 6 x 235-mL plastic bottles 4/case

SIMILAC PRO-ADVANCE® STEP 1With 2’-FL oligosaccharide/DHA- and ARA-fortifi ed For term infants 0+ months of age

2’-FL in breast milk helps build the baby’s immune

system. Our most advanced formula contains 2’-FL.*

* Not derived from human milk; identical structure to 2'-FL found in breast milk.† Breast milk is best for babies, contains many immune factors not available in infant formula,

and its use is recommended for as long as possible during infancy.‡ RRR-a-tocopherol, provided as d-a-tocopheryl acetate, the most bioactive form of vitamin E. § Ingredients not genetically engineered. ¥ Similar to other infant formulas.

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ENERGYPer 100 mL Per 100 Cal

ENERGY (Cal [kJ]) 68 (280) 100 (419)PROTEIN (g) 1.4 2.07 Tryptophan (mg) 22 33.1 Taurine (mg) 4.1 6.07 Carnitine (mg) 0.82 1.2Nucleotides (mg) 7.2 10.7FAT (g) 3.7 5.49 Linoleic Acid (g) 0.65 0.966 Linolenic Acid (g) 0.063 0.093 Arachidonic Acid (ARA) (g) 0.017 0.025 Docosahexaenoic Acid (DHA) (g) 0.011 0.016CARBOHYDRATE (g) 7.3 10.8 Fibre (g) 0.18 0.27 2’-fucosyllactose (2’-FL) (mg) 20 30

VITAMINSVitamin A (IU) 203 300Vitamin D (IU) 35 51.8Vitamin E (IU) 2.5 3.7Vitamin K (mg) 0.0083 0.0123Vitamin C (mg) 9.0 13.3Thiamine (mg) 0.064 0.0947Ribofl avin (mg) 0.11 0.163Niacin (mg) 0.45 0.666Pantothenic acid (mg) 0.40 0.59Vitamin B6 (mg) 0.054 0.0799Folic acid (mg) 0.0095 0.0141Vitamin B12 (mg) 0.00023 0.00034Biotin (mg) 0.0025 0.0037Choline (mg) 9.8 14.5Inositol (mg) 3.8 5.6Lutein (mg) 0.0053 0.0078

MINERALSSodium (mg) 18 26.6Potassium (mg) 79 117Chloride (mg) 40 59.2Calcium (mg) 53 78.4Phosphorus (mg) 26 38.5Magnesium (mg) 4.1 6.1Iron (mg) 1.1 1.63Zinc (mg) 0.45 0.67Iodine (mg) 0.0085 0.0126Copper (mg) 0.047 0.0695Manganese (mg) 0.004 0.0059Selenium (mg) 0.00080 0.00118Chromium (mg) 0 0Molybdenum (mg) 0 0

INGREDIENTSSimilac Pro-Advance® Step 1, Ready to use:Water, Lactose, Dry or evaporated skim milk, High oleic saffl ower oil, Soy oil, Coconut oil, Whey protein concentrate, Fructooligosaccharides, M. alpina oil (source of ARA), C. cohnii oil (source of DHA), Monoglycerides, Soy lecithin, 2’-fucosyllactose, Carrageenan, Taurine, M-inositol, Cytidine 5’-monophosphate, L-tryptophan, Disodium guanosine 5’-monophosphate, Disodium uridine 5’-monophosphate, Adenosine 5’-monophosphate, L-carnitine, Lutein, Minerals (potassium citrate, calcium carbonate, sodium citrate, potassium chloride, salt, potassium phosphate dibasic, magnesium chloride, ferrous sulphate, potassium hydroxide, zinc sulphate, magnesium sulphate, cupric sulphate, manganese sulphate, potassium iodide), Vitamins (ascorbic acid, choline bitartrate, choline chloride, D-alpha tocopheryl acetate, niacinamide, calcium D-pantothenate, vitamin A palmitate, thiamine hydrochloride, ribofl avin, pyridoxine hydrochloride, folic acid, phylloquinone, beta-carotene, D-biotin, vitamin D3, cyanocobalamin). As needed: Citric acid. Contains: Milk, Soy.

Values listed are subject to change. Please refer to the product label or packaging for the most current ingredient, allergen and nutrient profi le information.

REFERENCES:1. Weichert S et al. Nutr Res 2013;33(10):831-8. 2. Castanys-Muñoz E et al. Nutr Rev 2013;71(12):773-89. 3. Jantscher-Krenn E, Bode L. Human Milk Oligosaccharides: Role in Infant Health. Nutrition in Infancy (9781627032230) [Internet]. 2013 Jan [cited 2020 Mar 18];209. 4. Marriage B et al. JPGN 2015;61:649-53. 5. Kajzer J et al. FASEB J 2016;30(Supp):671.4. 6. Goehring KC et al. J Nutr 2016;146(12):2559-66. 7. Canadian Food Inspection Agency: Health Claims - Nutrient Function Claims. Last modifi ed on 2019-10-31. [Accessed online on 2020-07-17]. 8. Zimmer JP et al. Clin Ophtalmol 2007;1:25-35. 9. Krinsky NI et al. Ann Rev Nutr 2003;23:171-201. 10. Vishwanathan R et al. JPGN 2014;59(5):659-65. 11. Johnson EJ. Nutrition Reviews 2014;72(9):605-12. 12. Stone WL et al. Am J Clin Nutr 2003;77:899-906. 13. Institute of Medicine. Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium and Carotenoids. National Academy of Sciences. 2000. 14. Kuchan MJ et al. Curr Dev Nutr 2018;2:nzy055. 15. Kuchan MJ et al. Br J Nutr 2016;116:126-31.

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SIMILAC PRO-ADVANCE® STEP 2With 2’-FL oligosaccharide/DHA- and ARA-fortifi edFor infants and toddlers 6 to 24 months of age

INDICATIONS FOR USE• Transition formula for infants who are 6 months or older.• For oral or tube feeding use. Safety precaution:• Not for parenteral use.

FEATURES AND BENEFITS• Specially formulated to help bridge the nutritional intake gaps that can be associated with

the transition to table foods.• Calcium-enriched (~50% more calcium than Similac Pro-Advance® Step 1) to support

growing infants.• 2’-FL oligosaccharide is biosynthesized and structurally identical to 2’-FL human milk

oligosaccharide (HMO),1 the most abundant HMO found in the breast milk of mostmothers.2 HMOs help support the breastfed baby’s developing immune system.3

• Addition of 2’-FL* to infant formula may help support the development and regulation of the formula-fed baby’s immune response to be closer to that of breastfed infants.4†

• DHA, the most abundant Omega-3 fatty acid in the brain and eyes.5• Lutein, an antioxidant found in breast milk and concentrated in the infant brain and

eyes.6-8

- Recent studies show that lutein may have a role in visual and cognitive development.9• Vitamin E, a dietary antioxidant that protects fats in body tissues, like DHA, from

oxidation.10

- Similac Pro-Advance® uses natural vitamin E,‡ the most abundant form found in breast milk and in the infant brain.11-14

• Non-GMO.§ • Easy to digest.¥• Gluten-free.• Kosher.• Halal.

TECHNICAL DATAReady to use Powder

(at standard dilution)Caloric density (Cal/mL) 0.68 0.68Protein (% of total energy) 8.3 8.2 Protein source Dry or evaporated skim milk, whey

protein concentrateDry or evaporated skim milk, whey protein concentrate, whey protein

hydrolysate

Fat (% of total energy) 49.3 48.8Omega-6:Omega-3 ratio 8.43:1 9.7:1MCT oil (% of total fats) 0 0Fat source High oleic saffl ower oil, soy oil,

coconut oil, M. alpina oil, C. cohnii oil, monoglycerides, soy lecithin

High oleic saffl ower oil, soy oil, coconut oil, M. alpina oil, C. cohnii

oil, soy lecithinCarbohydrate (% of total energy) 42.4 43.0Carbohydrate source Lactose, fructooligosaccharides,

2’-fucosyllactoseLactose, fructooligosaccharides,

2’-fucosyllactoseTotal Cal:g nitrogen ratio 304:1 309:1Non-protein Cal:g nitrogen ratio 277:1 284:1

Water (g/L) 904 904Osmolality (mOsm/kg water) 306 303Renal solute load (mOsm/L) 127 97Minimum tube size for gravity/pump feeding (Fr)

N/A N/A

AVAILABILITYReady to use67268899 Similac Pro-Advance® Step 2 235-mL plastic bottles 16/case

Powder6720430B Similac Pro-Advance® Step 2 658-g containers 6/case67213356 Similac Pro-Advance® Step 2 964-g containers 6/case

* Not derived from human milk; identical structure to 2'-FL found in breast milk.† Breast milk is best for babies, contains many immune factors not available in infant formula, and its use is recommended for as long as possible during infancy.‡ RRR-a-tocopherol, provided as d-a-tocopheryl acetate, the most bioactive form of vitamin E. § Ingredients not genetically engineered. ¥ Similar to other infant formulas.

2’-FL in breast milk helps build the baby’s immune

system. Our most advanced formula contains 2’-FL.*

56

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SIMILAC PRO-ADVANCE® STEP 2With 2’-FL oligosaccharide/DHA- and ARA-fortifi edFor infants and toddlers 6 to 24 months of age

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Per 100 gPowder

Per 100 mL(at standard

dilution) Per 100 CalENERGY (Cal [kJ]) 516 (2160) 68 (280) 100 (418)PROTEIN (g) 11 1.4 2.1 Tryptophan (mg) 183 24 35 Taurine (mg) 35 4.5 6.7 Carnitine (mg) 7.6 0.99 1.5Nucleotides (mg) 55 7.2 10.7FAT (g) 29 3.7 5.5 Linoleic Acid (g) 4.0 0.53 0.78 Linolenic Acid (g) 0.38 0.050 0.075 Arachidonic Acid (ARA) (g) 0.11 0.014 0.0210 Docosahexaenoic Acid (DHA) (g) 0.055 0.0072 0.011CARBOHYDRATE (g) 56 7.3 10.8 Fibre (g) 1.4 0.18 0.27 2’-fucosyllactose (2’-FL) (mg) 153 20 30

VITAMINSVitamin A (IU) 1454 190 282Vitamin D (IU) 309 40 60Vitamin E (IU) 21 2.7 4.0Vitamin K (mg) 0.069 0.0090 0.0134Vitamin C (mg) 77 10 15Thiamine (mg) 0.61 0.080 0.12Ribofl avin (mg) 0.81 0.11 0.16Niacin (mg) 5.5 0.72 1.06Pantothenic acid (mg) 2.3 0.30 0.5Vitamin B6 (mg) 0.31 0.041 0.06Folic acid (mg) 0.053 0.0069 0.010Vitamin B12 (mg) 0.0013 0.00017 0.00026Biotin (mg) 0.019 0.0025 0.0037Choline (mg) 77 10 15Inositol (mg) 30 4.0 5.9Lutein (mg) 0.058 0.0076 0.011

MINERALSSodium (mg) 137 18 27Potassium (mg) 609 80 118Chloride (mg) 338 44 65Calcium (mg) 609 80 118Phosphorus (mg) 304 40 59Magnesium (mg) 40 5.2 7.7Iron (mg) 9.2 1.2 1.8Zinc (mg) 3.9 0.50 0.75Iodine (mg) 0.10 0.013 0.020Copper (mg) 0.41 0.053 0.079Manganese (mg) 0.037 0.0048 0.0071Selenium (mg) 0.010 0.0013 0.0020Chromium (mg) 0 0 0Molybdenum (mg) 0 0 0

Nutritional information for Similac Pro-Advance® Step 2, Powder.

INGREDIENTSSimilac Pro-Advance® Step 2, Ready to use: Water, Lactose, Dry or evaporated skim milk, High oleic safflower oil, Soy oil, Coconut oil, Whey protein concentrate, Fructooligosaccharides, M. alpina oil (source of ARA), C. cohnii oil (source of DHA), Monoglycerides, Soy lecithin, 2’-fucosyllactose, Carrageenan, Taurine, M-inositol, Cytidine 5’-monophosphate, L-tryptophan, Disodium guanosine 5’-monophosphate, Disodium uridine 5’-monophosphate, Adenosine 5’-monophosphate, L-carnitine, Lutein, Minerals (calcium phosphate, calcium carbonate, potassium citrate, potassium phosphate dibasic, sodium citrate, potassium chloride, salt, magnesium chloride, ferrous sulphate, potassium hydroxide, zinc sulphate, magnesium sulphate, cupric sulphate, manganese sulphate, potassium iodide), Vitamins (ascorbic acid, choline bitartrate, choline chloride, D-alpha tocopheryl acetate, niacinamide, calcium D-pantothenate, vitamin A palmitate, thiamine hydrochloride, riboflavin, pyridoxine hydrochloride, folic acid, phylloquinone, beta-carotene, D-biotin, vitamin D3, cyanocobalamin). As needed: Citric acid. Contains: Milk, Soy.

Similac Pro-Advance® Step 2, Powder: Lactose, Dry or evaporated skim milk, High oleic safflower oil, Soy oil, Coconut oil, Whey protein concentrate, Fructooligosaccharides, Whey protein hydrolysate, M. alpina oil (source of ARA), 2’-fucosyllactose, C. cohnii oil (source of DHA), Soy lecithin, L-tryptophan, Taurine, M-inositol, Cytidine 5’-monophosphate, Ascorbyl palmitate, Disodium guanosine 5’-monophosphate, Diso dium uridine 5’-monophosphate, Adenosine 5’-monophosphate, L-carnitine, Mixed tocopherols, Lutein, Minerals (tricalcium phosphate, potassium citrate, calcium carbonate, potassium hydroxide, magnesium chloride, salt, ferrous sulphate, zinc sulphate, cupric sulphate, potassium chloride, manganese sulphate, sodium selenite, potassium iodide), Vitamins (ascorbic acid, choline bitartrate, D-alpha tocopheryl acetate, niacinamide, calcium D-pantothenate, vitamin A palmitate, thiamine hydrochloride, riboflavin, pyridoxine hydrochloride, folic acid, beta-carotene, phylloquinone, D-biotin, vitamin D3, cyanocobalamin). Contains: Milk, Soy.

Values listed are subject to change. Please refer to the product label or packaging for the most current ingredient, allergen and nutrient profi le information.

REFERENCES: 1. Weichert S et al. Nutr Res. 2013;33(10):831-8. 2. Castanys-Muñoz E et al. Nutr Rev. 2013;71(12):773-89. 3. Jantscher-Krenn E, Bode L. Human Milk Oligosaccharides: Role in Infant Health. Nutrition in Infancy (9781627032230) [Internet]. 2013 Jan [cited 2020 Mar 18];209. 4. Goehring KC et al. J Nutr 2016;146(12):2559-66. 5. Calder PC. Ann Nutr Metab 2016;69(suppl 1):8-21. 6. Zimmer JP et al. Clin Ophtalmol 2007;1:25-35. 7. Krinsky NI et al. Ann Rev Nutr 2003;23:171-201. 8. Vishwanathan R et al. JPGN 2014;59(5);659-65. 9. Johnson EJ. Nutrition Reviews 2014;72(9):605-12. 10. Canadian Food Inspection Agency: Health Claims - Nutrient Function Claims. Last modifi ed on 2019-10-31. [Accessed online on 2020-07-17]. 11. Stone WL, et al. Am J Clin Nutr 2003;77:899-906. 12. Institute of Medicine. Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium and Carotenoids. National Academy of Sciences. 2000. 13. Kuchan MJ et al. Curr Dev Nutr 2018;2:nzy055. 14. Kuchan MJ et al. Br J Nutr 2016;116:126-31.

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SIMILAC® ADVANCE® STEP 1DHA- and ARA-enriched formulaFor term infants 0+ months of age

INDICATIONS FOR USE• For use as a breast milk substitute in infants who are not exclusively

breastfed.• For oral or tube feeding use.Safety precaution:• Not for parenteral use.FEATURES AND BENEFITS• DHA, the most abundant Omega-3 fatty acid in the brain and eyes.1• Lutein, an antioxidant found in breast milk and concentrated in the

infant brain and eyes.2-4

- Recent studies show that lutein may have a role in visual and cognitive development.5

• Vitamin E, an antioxidant found in breast milk.6,7

- Similac® Advance® uses natural vitamin E,† the most abundant form found in breast milk and in the infant brain.6-9

• Galactooligosaccharides (GOS), a type of oligosaccharide and dietary fi bre, that:

- Help promote softer stools, similar to those of breastfed babies.10

- May support the growth of good bacteria in the baby’s intestinal tract.11,12

• Non-GMO.‡• Easy to digest.§• Gluten-free.• Kosher.• Halal.TECHNICAL DATA

Powder(at standard dilution)

Caloric density (Cal/mL) 0.68Protein (% of total energy) 8.3Fat (% of total energy) 49.9Carbohydrate (% of total energy) 41.8Total Cal:g nitrogen ratio 309:1Non-protein Cal:g nitrogen ratio 284:1

Water (g/L) 901Osmolality (mOsm/kg water) 303Renal solute load (mOsm/L) 97Minimum tube size for gravity/pump feeding (Fr)

N/A

AVAILABILITYPowder 6499230B Similac® Advance® Step 1 658-g containers 6/case66982356 Similac® Advance® Step 1 964-g containers 6/case

Exclusive blend ofDHA, lutein, and natural vitamin E†

† RRR-a-tocopherol, provided as d-a-tocopheryl acetate, the most bioactive form of vitamin E. ‡ Ingredients not genetically engineered. § Similar to other infant formulas.REFERENCES: 1. Calder PC. Ann Nutr Metab 2016;69(Suppl. 1):8-21. 2. Zimmer JP et al. Clin Ophtalmol 2007;1:25-35. 3. Krinsky NI et al. Ann Rev Nutr 2003;23:171-201. 4. Vishwanathan R et al. JPGN 2014;59(5);659-65. 5. Johnson EJ. Nutrition Reviews 2014;72(9):605-12. 6. Stone WL et al. Am J Clin Nutr 2003;77:899-906. 7. Institute of Medicine. Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium and Carotenoids. National Academy of Sciences. 2000. 8. Kuchan MJ et al. Curr Dev Nutr 2018;2:nzy055. 9. Kuchan MJ et al. Br J Nutr 2016;116:126-31. 10. Williams T et al. JPGN 2014;59(5):653-8. 11. Ben XM et al. Chin Med J (Engl) 2004;117:927-31. 12. Ben XM et al. World J Gastroenterol 2008;14(42):6564-8.

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SIMILAC® ADVANCE® STEP 1DHA- and ARA-enriched formulaFor term infants 0+ months of age

ENERGY

Per 100 g Powder

Per 100 mL(at standard

dilution) Per 100 CalENERGY (Cal [kJ]) 509 (2130) 68 (283) 100 (418)PROTEIN (g) 10.6 1.4 2.1% of total energy 8.3 Tryptophan (mg) 180 24 35 Taurine (mg) 34.0 4.5 6.7 Carnitine (mg) 7.5 1.0 1.5Nucleotides (mg) 54.5 7.2 10.7Source Dry skim milk, whey protein concentrate,

whey protein hydrolysateFAT (g) 28.2 3.74 5.5% of total energy 49.9 Linoleic Acid (g) 3.97 0.53 0.78 Arachidonic Acid (ARA) (g) 0.107 0.0142 0.021 Linolenic Acid (g) 0.38 0.05 0.07 Docosahexaenoic Acid (DHA) (g) 0.051 0.0068 0.010 Omega-6:Omega-3 ratio 9.71:1Source High oleic saffl ower or sunflower oil, soy oil,

coconut oil, ARA and DHAMCT oil (% of total fats) 0.0 0.0 0.0CARBOHYDRATE (g) 55.0 7.3 10.8% of total energy 41.8 Fibre (g) 2.7 0.4 0.5 Short-chain fructooligosac-

charides (scFOS) (g)- - -

Galactooligosaccharides (GOS)¶ (g) 2.7 0.4 0.5Source Lactose, dry skim milk, galactooligosaccharidesAcesulfame-potassium (mg) - - -Sucralose (mg) - - -

VITAMINSVitamin A (IU) 1433 190 282Vitamin D (IU) 305 40.5 60Vitamin E (IU) 20.3 2.7 4.0Vitamin K (mg) 0.068 0.009 0.0134Vitamin C (mg) 76 10 15Thiamine (mg) 0.60 0.08 0.12Ribofl avin (mg) 0.80 0.11 0.16Niacin (mg) 5.40 0.72 1.06Vitamin B6 (mg) 0.31 0.04 0.06Folic acid (mg) 0.052 0.007 0.010Vitamin B12 (mg) 0.0013 0.0002 0.00026Pantothenic acid (mg) 2.3 0.3 0.5Biotin (mg) 0.019 0.003 0.0037Choline (mg) 76 10 15Inositol (mg) 30.0 4.0 5.9Lutein (mg) 0.057 0.0076 0.011

MINERALSSodium (mg) 135 18 27Potassium (mg) 600 80 118Chloride (mg) 333 44 65Calcium (mg) 400 53 79Phosphorus (mg) 216 29 42Magnesium (mg) 39.0 5.2 7.7Iron (mg) 9.1 1.2 1.8Zinc (mg) 3.80 0.5 0.75Iodine (mg) 0.100 0.013 0.020Copper (mg) 0.400 0.05 0.079Manganese (mg) 0.0363 0.005 0.0071Selenium (mg) 0.010 0.0013 0.002Chromium (mg) - - -Molybdenum (mg) - - -

INGREDIENTSSimilac® Advance® Step 1, Powder: Lactose, Dry or evaporated skim milk, High oleic vegetable oil (saffl ower or sunfl ower), Soy oil, Coconut oil, Galactooligosaccharides, Whey protein concentrate, Whey protein hydrolysate, Potassium citrate, Calcium carbonate, M. alpina oil (a source of ARA), Tricalcium phosphate, Potassium hydroxide, C. cohnii oil (a source of DHA), Soy lecithin, Magnesium chloride, Sodium chloride, Choline bitartrate, Ascorbic acid, L-tryptophan, Ferrous sulphate, Taurine, M-inositol, Cytidine 5'-monophosphate, Disodium guanosine 5'-monophosphate, Ascorbyl palmitate, Disodium uridine 5'-monophosphate, Zinc sulphate, D-alpha-tocopheryl acetate, Adenosine 5'-monophosphate, L-carnitine, Mixed tocopherols, Niacinamide, Calcium D-pantothenate, Copper sulphate, Vitamin A palmitate, Thiamine chloride hydrochloride, Pyridoxine hydrochloride, Ribofl avin, Lutein, Folic acid, Manganese sulphate, Beta-carotene, Phylloquinone, D-biotin, Sodium selenite, Potassium iodide, Vitamin D3, Cyanocobalamin. As needed: Potassium chloride. Contains: Milk, Soy.

Values listed are subject to change. Please refer to the product label or packaging for the most current ingredient, allergen and nutrient profi le information.

¶ GOS is approximately 1% of the total energy and provides approximately 1.3 Cal/g.

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INDICATIONS FOR USE• For use as a breast milk substitute in infants who are not exclusively breastfed.• For oral or tube feeding use.Safety precaution:• Not for parenteral use.FEATURES AND BENEFITS• DHA, an Omega-3 fatty acid that supports the normal physical

development of the brain and eyes.1• Lutein, an antioxidant found in breast milk and concentrated in the

infant brain and eyes.2-4

- Recent studies show that lutein may have a role in visual and cognitive development.5

• Vitamin E, an antioxidant found in breast milk.6,7

- Similac® Advance® uses natural vitamin E,† the most abundant form found in breast milk and in the infant brain.6-9

• Galactooligosaccharides (GOS), a type of oligosaccharide and dietary fi bre, that:

- Help promote softer stools, similar to those of breastfed babies.10

- May support the growth of good bacteria in the baby’s intestinal tract.11,12

• Non-GMO.‡• Easy to digest.§• Gluten-free.• Kosher.• Halal.TECHNICAL DATA

Concentrated liquid(at standard dilution)

Caloric density (Cal/mL) 0.68Protein (% of total energy) 8.2Fat (% of total energy) 48.2Carbohydrate (% of total energy) 43.6Total Cal:g nitrogen ratio 310:1Non-protein Cal:g nitrogen ratio 284:1

Water (g/L) 900Osmolality (mOsm/kg water) 300Renal solute load (mOsm/L) 131Minimum tube size for gravity/pump feeding (Fr)

N/A

AVAILABILITYConcentrated liquid66333510 Similac® Advance® Step 1 385-mL cans 12/case

† RRR-a-tocopherol, provided as d-a-tocopheryl acetate, the most bioactive form of vitamin E. ‡ Ingredients not genetically engineered. § Similar to other infant formulas.REFERENCES: 1. Canadian Food Inspection Agency: Health Claims – Nutrient Function Claims. Last modifi ed on 2019-10-31. [Accessed online on 2021-07-08]. 2. Zimmer JP et al. Clin Ophtalmol 2007;1:25-35. 3. Krinsky NI et al. Ann Rev Nutr 2003;23:171-201. 4. Vishwanathan R et al. JPGN 2014;59(5);659-65. 5. Johnson EJ. Nutrition Reviews 2014;72(9):605-12. 6. Stone WL et al. Am J Clin Nutr 2003;77:899-906. 7. Institute of Medicine. Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium and Carotenoids. National Academy of Sciences. 2000. 8. Kuchan MJ et al. Curr Dev Nutr 2018;2:nzy055. 9. Kuchan MJ et al. Br J Nutr 2016;116:126-31. 10. Williams T et al. JPGN 2014;59(5):653-8. 11. Ben XM et al. Chin Med J (Engl) 2004;117:927-31. 12. Ben XM et al. World J Gastroenterol 2008;14(42):6564-8.

SIMILAC® ADVANCE® STEP 1DHA- and ARA-enriched formulaFor term infants 0+ months of age

Exclusive blend ofDHA, lutein, andnatural vitamin E†IMAGEBANK

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SIMILAC® ADVANCE® STEP 1DHA- and ARA-enriched formulaFor term infants 0+ months of age

ENERGYPer 100 mL Per 100 Cal

ENERGY (Cal [kJ]) 135 (570) 100 (416)PROTEIN (g) 2.8 2.06% of total energy 8.2 Tryptophan (mg) 46 34.1 Taurine (mg) 9.0 6.7 Carnitine (mg) 1.8 1.3Nucleotides (mg) 14 10.6Source Dry skim milk, whey protein concentrateFAT (g) 7.3 5.37% of total energy 48.2 Linoleic Acid (g) 1.3 0.956 Arachidonic Acid (ARA) (g) 0.034 0.025 Linolenic Acid (g) 0.1 0.081 Docosahexaenoic Acid (DHA) (g) 0.023 0.017 Omega-6:Omega-3 ratio 9.41:1Source High oleic safflower oil, soy oil, coconut oil, ARA

and DHAMCT oil (% of total fats) 0.0CARBOHYDRATE (g) 15 11.4% of total energy 43.6 Fibre (g) 0.8 0.59 Short-chain fructooligosac- charides (scFOS) (g)

- -

Galactooligosaccharides (GOS)¶ (g) 0.8 0.59Source Lactose, galactooligosaccharidesAcesulfame-potassium (mg) - -Sucralose (mg) - -

VITAMINSVitamin A (IU) 406 299Vitamin D (IU) 81 60Vitamin E (IU) 5.2 3.8Vitamin K (mg) 0.011 0.0081Vitamin C (mg) 12 8.8Thiamine (mg) 0.14 0.100Ribofl avin (mg) 0.20 0.149Niacin (mg) 1.4 1.04Vitamin B6 (mg) 0.081 0.060Folic Acid (mg) 0.020 0.015Vitamin B12 (mg) 0.00046 0.00034Pantothenic Acid (mg) 0.80 0.588Biotin (mg) 0.006 0.0044Choline (mg) 22 16Inositol (mg) 6.0 4.7Lutein (mg) 0.011 0.0078

MINERALSSodium (mg) 32 24Potassium (mg) 154 113Chloride (mg) 88 65Calcium (mg) 105 78Phosphorus (mg) 57 42Magnesium (mg) 8.2 6.0Iron (mg) 2.4 1.8Zinc (mg) 1.0 0.75Iodine (mg) 0.018 0.013Copper (mg) 0.12 0.090Manganese (mg) 0.0068 0.005Selenium (mg) 0.0031 0.0023Chromium (mg) - -Molybdenum (mg) - -

INGREDIENTSSimilac® Advance® Step 1, Concentrated Liquid: Water, Lactose, Dry or evaporated skim milk, High oleic saffl ower oil, Soy oil, Galactooligosaccharides (GOS), Coconut oil, Whey protein concentrate, M. alpina oil (a source of ARA), Monoglycerides, Soy lecithin, C. cohnii oil (a source of DHA), L-tryptophan, Carrageenan, Taurine, Cytidine 5'-monophosphate, Citric acid, Disodium guanosine 5'-monophosphate, Disodium uridine 5'-monophosphate, Adenosine 5'-monophosphate, L-carnitine, Lutein, MINERALS (potassium citrate, calcium carbonate, potassium chloride, magnesium chloride, ferrous sulphate, zinc sulphate, cupric sulphate, manganese sulphate, sodium selenate), VITAMINS (choline bitartrate, ascorbic acid, M-inositol, D-alpha tocopheryl acetate, niacinamide, calcium D-pantothenate, vitamin A palmitate, thiamine chloride hydrochloride, ribofl avin, pyridoxine hydrochloride, folic acid, phylloquinone, biotin, beta-carotene, vitamin D3, cyanocobalamin). As needed: Potassium phosphate, Calcium phosphate, Potassium hydroxide, Sodium chloride, Potassium iodide. Contains: Milk, Soy.

Values listed are subject to change. Please refer to the product label or packaging for the most current ingredient, allergen and nutrient profi le information.

¶ GOS is approximately 1% of the total energy and provides approximately 1.3 Cal/g.

INGREDIENTS LISTAS PER COMMODITY #C6066-02

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SIMILAC® ADVANCE® STEP 2DHA- and ARA-enriched formulaFor infants and toddlers 6 to 24 months of age

INDICATIONS FOR USE• Transition formula for healthy, term infants who are 6 months

or older.• For oral or tube feeding use.Safety precaution:• Not for parenteral use.FEATURES AND BENEFITS• Specially formulated to help bridge the nutritional intake gaps that

can be associated with the transition to table foods.• Calcium-enriched (50% more calcium than Similac® Advance® Step 1)

to support growing infants.• DHA, the most abundant Omega-3 fatty acid in the brain and eyes.1• Lutein, an antioxidant found in breast milk and concentrated in the

infant brain and eyes.2-4

- Recent studies show that lutein may have a role in visual and cognitive development.5

• Vitamin E, an antioxidant found in breast milk.6,7

- Similac® Advance® uses natural vitamin E,† the most abundant form found in breast milk and in the infant brain.6-9

• Galactooligosaccharides (GOS), a type of oligosaccharide and dietary fi bre, that:

- Help promote softer stools, similar to those of breastfed babies.10

- May support the growth of good bacteria in the baby’s intestinal tract.11,12

• Non-GMO.‡• Easy to digest.§• Gluten-free.• Kosher.• Halal.TECHNICAL DATA

Concentrated liquid(at standard dilution)

Powder(at standard dilution)

Caloric density (Cal/mL) 0.68 0.68Protein (% of total energy) 8.2 8.3Fat (% of total energy) 48.2 49.9Carbohydrate (% of total energy) 43.6 41.8Total Cal:g nitrogen ratio 310:1 309:1Non-protein Cal:g nitrogen ratio 284:1 284:1

Water (g/L) 900 901Osmolality (mOsm/kg water) 305 303Renal solute load (mOsm/L) 131 97Minimum tube size for gravity/pump feeding (Fr)

N/A N/A

AVAILABILITYConcentrated liquid66336510 Similac® Advance® Step 2 385-mL cans 12/case

Powder6499130B Similac® Advance® Step 2 658-g containers 6/case66983356 Similac® Advance® Step 2 964-g containers 6/case

† RRR-a-tocopherol, provided as d-a-tocopheryl acetate, the most bioactive form of vitamin E. ‡ Ingredients not genetically engineered. § Similar to other infant formulas.REFERENCES: 1. Calder PC. Ann Nutr Metab 2016;69(Suppl. 1):8-21. 2. Zimmer JP et al. Clin Ophtalmol 2007;1:25-35. 3. Krinsky NI et al. Ann Rev Nutr 2003;23:171-201. 4. Vishwanathan R et al. JPGN 2014;59(5);659-65. 5. Johnson EJ. Nutrition Reviews 2014;72(9):605-12. 6. Stone WL et al. Am J Clin Nutr 2003;77:899-906. 7. Institute of Medicine. Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium and Carot-enoids. National Academy of Sciences. 2000. 8. Kuchan MJ et al. Curr Dev Nutr 2018;2:nzy055. 9. Kuchan MJ et al. Br J Nutr 2016;116:126-31. 10. Williams T et al. JPGN 2014;59(5):653-8. 11. Ben XM et al. Chin Med J (Engl) 2004;117:927-31. 12. Ben XM et al. World J Gastroenterol 2008;14(42):6564-8.

Exclusive blendof DHA, lutein, and natural vitamin E†

IMAGEBANKSEQ#15191

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SIMILAC® ADVANCE® STEP 2DHA- and ARA-enriched formulaFor infants and toddlers 6 to 24 months of age

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Per 100 gPowder

Per 100 mL(at standard

dilution) Per 100 CalENERGY (Cal [kJ]) 509 (2130) 68 (283) 100 (418)PROTEIN (g) 10.6 1.4 2.1% of total energy 8.3 Tryptophan (mg) 180 24 35 Taurine (mg) 34.0 4.5 6.7 Carnitine (mg) 7.5 1.0 1.5Nucleotides (mg) 54.5 7.2 10.6Source Dry skim milk, whey protein concentrate,

whey protein hydrolysateFAT (g) 28.2 3.74 5.5% of total energy 49.9 Linoleic Acid (g) 3.97 0.53 0.78 Arachidonic Acid (ARA) (g) 0.107 0.0142 0.0210 Linolenic Acid (g) 0.38 0.05 0.07 Docosahexaenoic Acid (DHA) (g) 0.051 0.0068 0.010 Omega-6:Omega-3 ratio 9.71:1Source High oleic safflower or sunflower oil, soy oil, coconut oil,

ARA and DHACARBOHYDRATE (g) 55.0 7.4 10.8% of total energy 41.8 Fibre (g) 2.7 0.4 0.5 Galactooligosaccharides (GOS)¶ (g) 2.7 0.4 0.5Source Lactose, dry skim milk, galactooligosaccharides

VITAMINSVitamin A (IU) 1433 190 282Vitamin D (IU) 305 40.5 60Vitamin E (IU) 20.3 2.7 4.0Vitamin K (mg) 0.068 0.009 0.0134Vitamin C (mg) 76 10 15Thiamine (mg) 0.60 0.08 0.12Ribofl avin (mg) 0.80 0.11 0.16Niacin (mg) 5.40 0.72 1.06Vitamin B6 (mg) 0.31 0.04 0.06Folic acid (mg) 0.052 0.007 0.010Vitamin B12 (mg) 0.0013 0.0002 0.00026Pantothenic acid (mg) 2.3 0.3 0.5Biotin (mg) 0.019 0.003 0.0037Choline (mg) 76 10 15Inositol (mg) 30.0 4.0 5.9Lutein (mg) 0.057 0.0076 0.011

MINERALSSodium (mg) 135 18 27Potassium (mg) 600 79 118Chloride (mg) 333 44 65Calcium (mg) 600 80 118Phosphorus (mg) 300 40 59Magnesium (mg) 39.0 5.2 7.7Iron (mg) 9.1 1.2 1.8Zinc (mg) 3.80 0.5 0.75Iodine (mg) 0.100 0.013 0.020Copper (mg) 0.400 0.05 0.079Manganese (mg) 0.0363 0.005 0.0071Selenium (mg) 0.010 0.0013 0.002Chromium (mg) - - -Molybdenum (mg) - - -Nutritional information for Similac® Advance® Step 2, Powder.

INGREDIENTSSimilac® Advance® Step 2, Powder: Lactose, Dry skim milk, High oleic vegetable oil (safflower or sunflower), Soy oil, Coconut oil, Galactooligosaccharides (GOS), Whey protein concentrate, Tricalcium phosphate, Whey protein hydrolysate, Potassium citrate, M. alpina oil (a source of ARA), Calcium carbonate, Potassium hydroxide, C. cohnii oil (a source of DHA), Soy lecithin, Magnesium chloride, Sodium chloride, Choline bitartrate, Ascorbic acid, L-tryptophan, Ferrous sulphate, Taurine, M-inositol, Cytidine 5'-monophosphate, Disodium guanosine 5'-monophosphate, Ascorbyl palmitate, Disodium uridine 5'-monophosphate, Zinc sulphate, D-alpha-tocopheryl acetate, Adenosine 5'-monophosphate, L-carnitine, Mixed tocopherols, Niacinamide, Calcium D-pantothenate, Copper sulphate, Vitamin A palmitate, Thiamine hydrochloride, Pyridoxine hydrochloride, Riboflavin, Lutein, Folic acid, Manganese sulphate, Beta-carotene, Phylloquinone, D-biotin, Sodium selenite, Potassium iodide, Vitamin D3, Cyanocobalamin. As needed: Potassium chloride.Contains: Milk, Soy.

Similac® Advance® Step 2, Concentrated Liquid: Water, Lactose, Dry or evaporated skim milk, High oleic safflower oil, Soy oil, Galactooligosaccharides (GOS), Coconut oil, Whey protein concentrate, M. alpina oil(a source of ARA), Monoglycerides, Soy lecithin, C. cohnii oil (a source of DHA), L-tryptophan, Carrageenan, Taurine, Cytidine 5'-monophosphate, Citric acid, Disodium guanosine 5'-monophosphate, Disodium uridine 5'-monophosphate, Adenosine 5'-monophosphate, L-carnitine, Lutein, MINERALS (calcium phosphate, potassium citrate, calcium carbonate, potassium chloride, magnesium chloride, ferrous sulphate, zinc sulphate, cupric sulphate, manganese sulphate, sodium selenate), VITAMINS (choline bitartrate, ascorbic acid, D-alpha tocopheryl acetate, niacinamide, calcium D-pantothenate, vitamin A palmitate, thiamine chloride hydrochloride, riboflavin, pyridoxine hydrochloride, folic acid, phylloquinone, beta-carotene, biotin, vitamin D3, cyanocobalamin). As needed: Potassium phosphate, Potassium hydroxide, Sodium chloride, Potassium iodide. Contains: Milk, Soy.

Values listed are subject to change. Please refer to the product label or packaging for the most current ingredient, allergen and nutrient profi le information.

¶ GOS is approximately 1% of the total energy and provides approximately 1.3 Cal/g.

INGREDIENTS LISTPOWDER COMMODITY #C6086-01

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SIMILAC® STEP 1Milk-based formula For term infants 0+ months of age

INDICATIONS FOR USE• For use as a breast milk substitute in infants who are not exclusively

breastfed.• For oral or tube feeding use.Safety precaution:• Not for parenteral use.

FEATURES AND BENEFITS• Non-GMO.†• Easy to digest.‡

TECHNICAL DATAPowder

(at standard dilution)

Caloric density (Cal/mL) 0.68Protein (% of total energy) 8.2Fat (% of total energy) 48.8Carbohydrate (% of total energy) 43.0Total Cal:g nitrogen ratio 304.8:1Non-protein Cal:g nitrogen ratio 279.8:1

Water (g/L) 901Osmolality (mOsm/kg water) 303Renal solute load (mOsm/L) 97Minimum tube size for gravity/pump feeding (Fr)

N/A

Low residue YesGluten-free YesKosher YesHalal Yes

AVAILABILITYPowder0S250301 Similac® Step 1 850-g cans 6/case

† Ingredients not genetically engineered.‡ Similar to other infant formulas.

IMAGEBANKcommodity# 501-955-000

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SIMILAC® STEP 1Milk-based formula For term infants 0+ months of age

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Per 100 gPowder

Per 100 mL(at standard dilution)

ENERGY (Cal [kJ]) 515 (2146) 68 (283)PROTEIN (g) 10 1.3 % of total energy 8.2 Tryptophan (mg) 162 21 Taurine (mg) 31 4.1 Carnitine (mg) 7.5 1.0 Nucleotides (mg) 55 7.2 Source Skim milk, whey protein concentrate, whey protein

hydrolysateFAT (g) 27 3.6 % of total energy 48.8 Linoleic Acid (g) 4.0 0.5 Arachidonic Acid (ARA) (g) - - Linolenic Acid (g) 0.4 0.05 Docosahexaenoic Acid (DHA) (g) - - Omega-6:Omega-3 ratio 11.9:1Source High oleic sunfl ower oil, soy oil, coconut oilMCT oil (% of total fats) 0.0CARBOHYDRATE (g) 58 7.6 % of total energy 43.0 Total dietary fi bre (g) - - Short-chain fructooligosac-

charides (scFOS) (g)- -

Galactooligosaccharides (GOS) (g) - -Source LactoseAcesulfame-potassium (mg) - -Sucralose (mg) - -

VITAMINSVitamin A (IU) 1511 199Vitamin D (IU) 236 31Vitamin E (IU) 19 2.5Vitamin K (mg) 0.046 0.006Vitamin C (mg) 76 10Thiamine (mg) 0.54 0.07Ribofl avin (mg) 1.1 0.14Niacin (mg) 4.9 0.65Vitamin B6 (mg) 0.31 0.04Folic acid (mg) 0.052 0.0068Vitamin B12 (mg) 0.0013 0.00017Pantothenic acid (mg) 2.7 0.36Biotin (mg) 0.017 0.0022Choline (mg) 68 9Inositol (mg) 27 3.6

MINERALSSodium (mg) 122 16Potassium (mg) 567 75Chloride (mg) 300 40Calcium (mg) 360 47Phosphorus (mg) 194 26Magnesium (mg) 35 4.6Iron (mg) 8.1 1.1Zinc (mg) 3.4 0.4Iodine (mg) 0.09 0.012Copper (mg) 0.35 0.046Manganese (mg) 0.09 0.012Selenium (mg) 0.0072 0.0009Chromium (mg) - -Molybdenum (mg) - -

INGREDIENTSSimilac® Step 1, Powder:Skim milk and/or dry skim milk, Lactose, High oleic sunfl ower oil, Soy oil, Coconut oil, Whey protein concentrate, Whey protein hydrolysate, Soy lecithin, Taurine, L-tryptophan, Cytidine 5'-monophosphate, M-inositol, Ascorbyl palmitate, Disodium guanosine 5'-monophosphate, Disodium uridine 5'-monophosphate, Adenosine 5'-monophosphate, Tocopherols, L-carnitine, Minerals (potassium citrate, calcium carbonate, magnesium chloride, sodium chloride, potassium chloride, ferrous sulphate, zinc sulphate, copper sulphate, manganese sulphate, potassium iodide, sodium selenate), Vitamins (ascorbic acid, choline bitartrate, D-alpha-tocopheryl acetate, niacinamide, calcium D-pantothenate, vitamin A palmitate, thiamine chloride hydrochloride, pyridoxine hydrochloride, ribofl avin, beta-carotene, folic acid, phylloquinone, D-biotin, vitamin D3, cyanocobalamin). As needed: Tricalcium phosphate. Contains: Milk, Soy.

Values listed are subject to change. Please refer to the product label or packaging for the most current ingredient, allergen and nutrient profi le information.

INGREDIENTS LISTAS PER COMMODITY #501-149-004

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IMAGEBANKcommodity# 501-953-000

sequence#15308

SIMILAC® STEP 2Calcium-enriched, milk-based formulaFor infants and toddlers 6 to 24 months of age

INDICATIONS FOR USE• For use as a breast milk substitute for infants who are not exclusively

breastfed. • For use in infants 6 months and older as they transition to solid

foods.• For oral or tube feeding use.Safety precaution:• Not for parenteral use.

FEATURES AND BENEFITS• Specially formulated to help bridge the nutritional gaps that

can be associated with the transition to table foods.• Calcium enriched (50% more calcium than Similac® Step 1)

to support growing bones.• Non-GMO.†• Easy to digest.‡

TECHNICAL DATA

Powder(at standard dilution)

Caloric density (Cal/mL) 0.68Protein (% of total energy) 8.2Fat (% of total energy) 48.8Carbohydrate (% of total energy) 43.0Total Cal:g nitrogen ratio 304.8:1Non-protein Cal:g nitrogen ratio 279.8:1

Water (g/L) 901Osmolality (mOsm/kg water) 303Renal solute load (mOsm/L) 97Minimum tube size for gravity/pump feeding (Fr)

N/A

Low residue YesGluten-free YesKosher YesHalal Yes

AVAILABILITYPowder0S252301 Similac® Step 2 850-g cans 6/case

† Ingredients not genetically engineered.‡ Similar to other infant formulas.

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INGREDIENTS LISTAS PER COMMODITY #501-149-004

SIMILAC® STEP 2Calcium-enriched, milk-based formulaFor infants and toddlers 6 to 24 months of age

NU

TRITIO

NA

L INFO

RM

ATIO

NENERGY

Per 100 gPowder

Per 100 mL(at standard dilution)

ENERGY (Cal [kJ]) 515 (2146) 68 (283)PROTEIN (g) 10 1.3% of total energy 8.2 Tryptophan (mg) 162 21 Taurine (mg) 31 4.1 Carnitine (mg) 7.5 1.0Nucleotides (mg) 55 7.2Source Skim milk, whey protein concentrate, whey protein

hydrolysateFAT (g) 27 3.6% of total energy 48.8 Linoleic Acid (g) 4.0 0.5 Arachidonic Acid (ARA) (g) - - Linolenic Acid (g) 0.4 0.05 Docosahexaenoic Acid (DHA) (g) - - Omega-6:Omega-3 ratio 11.9:1Source High oleic sunfl ower oil, soy oil, coconut oilMCT oil (% of total fats) 0.0CARBOHYDRATE (g) 57.9 7.6% of total energy 43.0 Fibre (g) - - Short-chain fructooligosac-

charides (scFOS) (g)- -

Galactooligosaccharides (GOS) (g) - -Source Lactose Acesulfame-potassium (mg) - -Sucralose (mg) - -

VITAMINSVitamin A (IU) 1511 199Vitamin D (IU) 236 31Vitamin E (IU) 19 2.5Vitamin K (mg) 0.046 0.006Vitamin C (mg) 76 10Thiamine (mg) 0.54 0.07Ribofl avin (mg) 1.1 0.14Niacin (mg) 4.9 0.65Vitamin B6 (mg) 0.31 0.04Folic acid (mg) 0.052 0.0068Vitamin B12 (mg) 0.0013 0.00017Pantothenic acid (mg) 2.7 0.36Biotin (mg) 0.017 0.0022Choline (mg) 68 9.0Inositol (mg) 27 3.6Lutein (mg) - -

MINERALSSodium (mg) 122 16Potassium (mg) 567 75Chloride (mg) 300 40Calcium (mg) 546 72Phosphorus (mg) 293 39Magnesium (mg) 35 4.6Iron (mg) 8.1 1.1Zinc (mg) 3.4 0.4Iodine (mg) 0.09 0.012Copper (mg) 0.35 0.046Manganese (mg) 0.09 0.012Selenium (mg) 0.0072 0.0009Chromium (mg) - -Molybdenum (mg) - -

COMPOSITIONSimilac® Step 2, Powder:Skim milk and/or dry skim milk, Lactose, High oleic sunfl ower oil, Soy oil, Coconut oil, Whey protein concentrate, Whey protein hydrolysate, Soy lecithin, Taurine, L-tryptophan, Cytidine 5’-monophosphate, M-inositol, Ascorbyl palmitate, Disodium guanosine 5’-monophosphate, Disodium uridine 5’-monophosphate, Adenosine 5’-monophosphate, Tocopherols, L-carnitine, Minerals (potassium citrate, tri calcium phosphate, calcium carbonate, magnesium chloride, potassium chloride, sodium chloride, ferrous sulphate, zinc sulphate, copper sulphate, manganese sulphate, potassium iodide, sodium selenate), Vitamins (ascorbic acid, choline bitartrate, D-alpha-tocopheryl acetate, niacinamide, calcium D-pantothenate, vitamin A palmitate, thiamine chloride hydrochloride, pyridoxine hydrochloride, ribofl avin, beta-carotene, folic acid, phylloquinone, D-biotin, vitamin D3, cyanocobal amin). Contains: Milk, Soy.

Values listed are subject to change. Please refer to the product label or packaging for the most current ingredient, allergen and nutrient profi le information.

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SIMILAC® LOWER IRONMilk-based formulaFor term infants 0+ months of age

INDICATIONS FOR USE• For use as a breast milk substitute in infants who are not exclusively breastfed.• For infants whose health care professional recommends a lower

iron formulation.• For oral or tube feeding use.Safety precautions:• A standard infant formula, containing a higher amount of iron, may

need to be recommended for infants at risk of iron defi ciency.1• Not for parenteral use.

FEATURES AND BENEFITS• Lower iron content (0.66 mg/100 mL) than Similac® Step 1

(1.1 mg/100 mL).• Non-GMO.†• Easy to digest.‡

TECHNICAL DATAPowder

(at standard dilution)Caloric density (Cal/mL) 0.68Protein (% of total energy) 8.2Fat (% of total energy) 48.8Carbohydrate (% of total energy) 43.0Total Cal:g nitrogen ratio 304.8:1Non-protein Cal:g nitrogen ratio 279.8:1

Water (g/L) 901Osmolality (mOsm/kg water) 303Renal solute load (mOsm/L) 97Minimum tube size for gravity/pump feeding (Fr)

N/A

Low-residue YesGluten-free YesKosher YesHalal Yes

AVAILABILITYPowder0S225301 Similac® Lower Iron 850-g cans 6/case

† Ingredients not genetically engineered.‡ Similar to other infant formulas.

REFERENCE:1. Health Canada, Canadian Paediatric Society, Dietitians of Canada, and Breastfeeding Committee for

Canada (2015). Nutrition for healthy term infants: Recommendations from birth to six months. Last modifi ed 2015-08-18. [Accessed online 2021-07-08].

IMAGEBANKSEQ#15307

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SIMILAC® LOWER IRONMilk-based formulaFor term infants 0+ months of age

NU

TRITIO

NA

L INFO

RM

ATIO

NENERGY

Per 100 gPowder

Per 100 mL(at standard dilution)

ENERGY (Cal [kJ]) 513 (2146) 68 (283)PROTEIN (g) 10.07 1.3% of total energy 8.2 Tryptophan (mg) 162 21.3 Taurine (mg) 30.6 4.0 Carnitine (mg) 7.5 1.0Nucleotides (mg) 54.7 7.2Source Skim milk, whey protein concentrate, whey protein

hydrolysateFAT (g) 26.79 3.53% of total energy 48.8 Linoleic Acid (g) 3.97 0.52 Arachidonic Acid (ARA) (g) - - Linolenic Acid (g) 0.38 0.05 Docosahexaenoic Acid (ADH) (g) - - Omega-6:Omega-3 ratio 11.9 :1Source High oleic sunfl ower oil, soy oil, coconut oilMCT oil (% of total fats) 0.0CARBOHYDRATE (g) 57.9 7.6% of total energy 43.0 Fibre (g) - - Fructooligosaccharides (FOS) (g) - - Galactooligosaccharides (GOS) (g) - -Source LactoseAcesulfame-potassium (mg) - -Sucralose (mg) - -

VITAMINSVitamin A (IU) 1433 189Vitamin D (IU) 236 31Vitamin E (IU) 19.2 2.5Vitamin K (mg) 0.046 0.006Vitamin C (mg) 76 10Thiamine (mg) 0.54 0.07Ribofl avin (mg) 1.1 0.14Niacin (mg NE) 4.9 0.65Vitamin B6 (mg) 0.31 0.04Folic acid (mg) 0.052 0.0068Vitamin B12 (mg) 0.00130 0.00017Pantothenic acid (mg) 2.7 0.36Biotin (mg) 0.017 0.0022Choline (mg) 68 9.0Inositol (mg) 27 3.6Lutein (mg) - -

MINERALSSodium (mg) 122 16Potassium (mg) 567 75Chloride (mg) 300 40Calcium (mg) 360 47Phosphorus (mg) 194 26Magnesium (mg) 35.1 4.6Iron (mg) 4.95 0.65Zinc (mg) 3.4 0.4Iodine (mg) 0.090 0.012Copper (mg) 0.347 0.046Manganese (mg) 0.090 0.012Selenium (mg) 0.0072 0.0009Chromium (mg) - -Molybdenum (mg) - -

INGREDIENTSSimilac® Lower Iron, Powder:Skim milk and/or dry skim milk, Lactose, High oleic sunfl ower oil, Soy oil, Coconut oil, Whey protein concentrate, Whey protein hydrolysate, Soy lecithin, Taurine, L-tryptophan, Cytidine 5’-monophosphate, M-inositol, Ascorbyl palmitate, Disodium guanosine 5’-monophosphate, Disodium uridine 5’-monophosphate, Adenosine 5’-monophosphate, Tocophe-rols, L-carnitine, Minerals (potassium citrate, calcium carbonate, magnesium chloride, sodium chloride, potassium chloride, ferrous sulphate, zinc sulphate, copper sulphate, manganese sulphate, potassium iodide, sodium selenate), Vitamins (ascorbic acid, choline bitartrate, D-alpha-tocopheryl acetate, niacinamide, calcium D-pantothenate, vitamin A palmitate, thiamine chloride hydrochloride, pyridoxine hydrochloride, ribofl avin, beta-carotene, folic acid, phylloquinone, D-biotin, vitamin D3, cyanocobalamin). As needed: Tricalcium phosphate. Contains: Milk, Soy.

Values listed are subject to change. Please refer to the product label or packaging for the most current ingredient, allergen and nutrient profi le information.

INGREDIENTS LISTPOWDER COMMODITY #501-956-000

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SIMILAC TOTAL COMFORT®Partially hydrolyzed whey protein formulaFor term infants 0+ months of age

INDICATIONS FOR USE• For use as a breast milk substitute in infants who are not exclusively breastfed.• For oral or tube feeding use.Safety precaution:• Not for parenteral use.

FEATURES AND BENEFITS• 100% partially hydrolyzed whey protein.• DHA, the most abundant Omega-3 fatty acid in the brain and eyes.1• Non-GMO.†• Easy to digest.‡

TECHNICAL DATAPowder

(at standard dilution)Caloric density (Cal/mL) 0.68Protein (% of total energy) 9.4Fat (% of total energy) 48.5Carbohydrate (% of total energy) 42.1Total Cal:g nitrogen ratio 264:1Non-protein Cal:g nitrogen ratio 239:1

Water (g/L) 900Osmolality (mOsm/kg water) 180Renal solute load (mOsm/L) 158Minimum tube size for gravity/pump feeding (Fr)

N/A

Low residue YesGluten-free YesKosher YesHalal Yes

AVAILABILITYPowder6635030C Similac Total Comfort® 638-g containers 6/case

66984356 Similac Total Comfort® 964-g containers 6/case

† Ingredients not genetically engineered. ‡ Similar to other infant formulas.REFERENCE:1. Calder PC. Ann Nutr Metab 2016;69(Suppl. 1):8-21.

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SIMILAC TOTAL COMFORT® Partially hydrolyzed whey protein formulaFor term infants 0+ months of age

NU

TRITIO

NA

L INFO

RM

ATIO

NENERGY

Per 100 gPowder

Per 100 mL(at standard

dilution) Per 100 CalENERGY (Cal [kJ]) 511 (2138) 67.6 (283) 100 (418)PROTEIN (g) 11.80 1.60 2.31% of total energy 9.4 Taurine (mg) 34.2 4.5 6.7 Carnitine (mg) 9.7 1.3 1.9Nucleotides (mg) 54.6 7.30 10.7Source Whey protein hydrolysateFAT (g) 27.60 3.65 5.41% of total energy 48.5 Linoleic Acid (g) 4.16 0.551 0.81 Arachidonic Acid (ARA) (g) 0.102 0.014 0.02 Linolenic Acid (g) 0.434 0.057 0.08 Docosahexaenoic Acid (DHA) (g) 0.050 0.007 0.01 Omega-6:Omega-3 ratio 9.81:1Source High oleic saffl ower oil, coconut oil, soy oil, ARA and DHAMCT oil (% of total fats) 0.0CARBOHYDRATE (g) 53.90 7.13 10.50% of total energy 42.1 Fibre (g) - - - Short-chain fructooligosac-

charides (scFOS) (g)- - -

Galactooligosaccharides (GOS) (g) - - -Source Corn maltodextrin, sucroseAcesulfame-potassium (mg) - - -Sucralose (mg) - - -

VITAMINSVitamin A (IU) 1532 203 300Vitamin D (IU) 306 40.5 60Vitamin E (IU) 15.3 2.0 3.0Vitamin K (mg) 0.0511 0.0068 0.010Vitamin C (mg) 63.8 8.50 12.5Thiamine (mg) 0.44 0.058 0.09Ribofl avin (mg) 0.51 0.0683 0.10Niacin (mg) 5.36 0.710 1.05Vitamin B6 (mg) 0.36 0.0452 0.07Folic acid (mg) 0.076 0.01 0.015Vitamin B12 (mg) 0.00225 0.0003 0.00044Pantothenic acid (mg) 3.78 0.501 0.74Biotin (mg) 0.0225 0.003 0.0044Choline (mg) 76.6 10.1 15.0Inositol (mg) 25.5 3.4 5.0Lutein (mg) - - -

MINERALSSodium (mg) 225 30 44Potassium (mg) 671 88.8 131Chloride (mg) 408 54 80Calcium (mg) 536 71 105Phosphorus (mg) 383 51 75Magnesium (mg) 38.3 5.1 7.5Iron (mg) 7.66 1.01 1.50Zinc (mg) 4.14 0.55 0.81Iodine (mg) 0.077 0.0101 0.015Copper (mg) 0.460 0.061 0.090Manganese (mg) 0.036 0.005 0.007Selenium (mg) 0.012 0.00163 0.0024Chromium (mg) - - -Molybdenum (mg) - - -

INGREDIENTSSimilac Total Comfort®, Powder:Corn maltodextrin, Whey protein hydrolysate, High oleic saffl ower oil, Sucrose, Soy oil, Coconut oil, Calcium citrate, Potassium phosphate, Calcium phosphate, M. alpina oil (a source of ARA), Potassium hydroxide, Sodium chloride, Magnesium chloride, Ascorbic acid, C. cohnii oil (a source of DHA), Potassium chloride, Choline chloride, Calcium hydroxide, Taurine, Choline bitartrate, M-inositol, Ferrous sulphate, Cytidine 5’-monophosphate, Zinc sulphate, Disodium guanosine 5’-monophosphate, Ascorbyl palmitate, D-alpha-tocopheryl acetate, L-carnitine, Disodium uridine 5’-monophosphate, Adenosine 5’-monophosphate, Mixed tocopherols, Niacinamide, Calcium pantothenate, Potassium citrate, Cupric sulphate, Vitamin A palmitate, Ribofl avin, Thiamine chloride hydrochloride, Pyridoxine hydrochloride, Manganese sulphate, Folic acid, Potassium iodide, Phylloquinone, Sodium selenate, Biotin, Vitamin D3, Cyanocobalamin. Contains: Milk.

Values listed are subject to change. Please refer to the product label or packaging for the most current ingredient, allergen and nutrient profi le information.

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SIMILAC® SENSITIVE® LACTOSE SENSITIVITYFormula with lactose-free carbohydrate source†

For term infants 0+ months of age

INDICATIONS FOR USE• For infants with symptoms of lactose intolerance such as fussiness,

gas, and/or diarrhea.1• For use as a breast milk substitute in infants who are not exclusively

breastfed.• For oral or tube feeding use.Safety precautions:• Not for parenteral use.• Not for infants with galactosemia, congenital lactase defi ciency,

or confi rmed cow’s milk protein allergy.2

FEATURES AND BENEFITS• Lactose-free carbohydrate source.†• Non-GMO.‡• Easy to digest.§

TECHNICAL DATAConcentrated

liquid(at standard

dilution)

Powder(at standard

dilution)Caloric density (Cal/mL) 0.68 0.68Protein (% of total energy) 8.6 8.7Fat (% of total energy) 48.6 48.8Carbohydrate (% of total energy) 42.8 42.5Total Cal:g nitrogen ratio 297:1 293:1Non-protein Cal:g nitrogen ratio 272:1 268:1

Water (g/L) 900 901Osmolality (mOsm/kg water) 215 200Renal solute load (mOsm/L) 136 136Minimum tube size for gravity/pump feeding (Fr)

N/A N/A

Low residue Yes YesGluten-free Yes YesKosher Yes YesHalal Yes Yes

AVAILABILITYConcentrated liquid66338510 Similac® Sensitive® 385-mL cans 12/case Lactose Sensitivity

Powder6499830C Similac® Sensitive® 638-g containers 6/case Lactose Sensitivity

† Contains inherent lactose from protein source.‡ Ingredients not genetically engineered.§ Similar to other infant formulas.REFERENCES:1. Lasekan JB et al. Lactose-free Milk Protein-Based Formula: Impact on Growth and Gastrointestinal Tolerance in Infants. Clin Pediatr 2011;50(4):330-7. 2. Health Canada, Canadian Paediatric Society, Dietitians of Canada, and Breastfeeding Committee for Canada (2015) Nutrition for healthy term infants: Recommendations from birth to six months. Last modifi ed 2015-08-18. [Accessed online 2021-07-08].

IMAGEBANKSEQ#15062

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NU

TRITIO

NA

L INFO

RM

ATIO

NENERGY

Per 100 gPowder

Per 100 mL(at standard

dilution) Per 100 CalENERGY (Cal [kJ]) 514 (2151) 68 (283) 100 (418)PROTEIN (g) 11.20 1.47 2.18% of total energy 8.7 Taurine (mg) 34.6 4.6 6.7 Carnitine (mg) 8.4 1.1 1.6Nucleotides (mg) 54.7 7.2 10.6Source Milk protein concentrate, whey protein hydrolysate FAT (g) 28.00 3.68 5.45% of total energy 48.8 Linoleic Acid (g) 3.97 0.52 0.77 Arachidonic Acid (ARA) (g) - - - Linolenic Acid (g) 0.38 0.05 0.07 Docosahexaenoic Acid (DHA) (g) - - - Omega-6:Omega-3 9.5:1Source High oleic vegetable oil (saffl ower or sunfl ower),

coconut oil, soy oilMCT oil (% of total fats) 0.0CARBOHYDRATE (g) 55.0 7.24 10.7% of total energy 42.5 Fibre (g) - - - Short-chain fructooligosac- charides (scFOS) (g)

- - -

Galactooligosaccharides (GOS) (g) - - -Source Corn syrup, sucroseAcesulfame-potassium (mg) - - -Sucralose (mg) - - -

VITAMINSVitamin A (IU) 1433 189 279Vitamin D (IU) 305 40 59Vitamin E (IU) 20.3 2.7 3.9Vitamin K (mg) 0.068 0.0089 0.0132Vitamin C (mg) 76.0 10.0 15.0Thiamine (mg) 0.60 0.08 0.12Ribofl avin (mg) 0.34 0.05 0.07Niacin (mg) 5.40 0.70 1.05Vitamin B6 (mg) 0.31 0.04 0.06Folic acid (mg) 0.076 0.010 0.015Vitamin B12 (mg) 0.00114 0.00015 0.00022Pantothenic acid (mg) 2.30 0.30 0.45Biotin (mg) 0.019 0.0025 0.0037Choline (mg) 62.0 8.2 12.1Inositol (mg) 30.0 3.9 5.8Lutein (mg) - - -

MINERALSSodium (mg) 154 20 30Potassium (mg) 620 82 121Chloride (mg) 338 45 66Calcium (mg) 441 58 86Phosphorus (mg) 276 36 54Magnesium (mg) 31.5 4.2 6.1Iron (mg) 9.10 1.20 1.80Zinc (mg) 3.80 0.50 0.74Iodine (mg) 0.090 0.012 0.018Copper (mg) 0.408 0.054 0.0793Manganese (mg) 0.0363 0.005 0.0071Selenium (mg) 0.010 0.0013 0.0019Chromium (mg) - - -Molybdenum (mg) - - -Nutritional information for Similac® Sensitive® Lactose Sensitivity, Powder.

INGREDIENTSSimilac® Sensitive® Lactose Sensitivity, Powder: Corn syrup, Sucrose, Milk protein concentrate, High oleic vegetable oil (saffl ower or sunfl ower), Coconut oil, Soy oil, Potassium citrate, Sodium citrate, Potassium chloride, Calcium phosphate, Whey protein hydrolysate, Ascorbic acid, Magnesium phosphate, Choline chloride, Magnesium chloride, Choline bitartrate, Ferrous sulphate, Taurine, M-inositol, Cytidine 5'-monophosphate, Ascorbyl palmitate, Disodium guanosine 5'-monophosphate, D-alpha-tocopheryl acetate, Disodium uridine 5'-monophosphate, L-carnitine, Zinc sulphate, Adenosine 5'-monophosphate, Mixed tocopherols, Niacinamide, Potassium hydroxide, Calcium D-pantothenate, Cupric sulphate, Vitamin A palmitate, Thiamine hydrochloride, Ribofl avin, Pyridoxine hydrochloride, Potassium iodide, Folic acid, Manganese sulphate, Phylloquinone, Biotin, Sodium selenite, Vitamin D3, Cyanocobalamin. As needed: Calcium carbonate. Contains: Milk, Soy.Similac® Sensitive® Lactose Sensitivity, Concentrated Liquid: Water, Corn maltodextrin, Sucrose, Milk protein isolate, High oleic saffl ower oil, Soy oil, Coconut oil, Modifi ed cornstarch, M. alpina oil (a source of ARA), Monoglycerides, Soy lecithin, C. cohnii oil (a source of DHA), Carrageenan, Taurine, Cytidine 5’-monophosphate, Disodium guanosine 5’-monophosphate, Disodium uridine 5’-monophosphate, Adenosine 5’-monophosphate, L-carnitine, MINERALS (calcium phosphate, potassium citrate, potassium chloride, magnesium chloride, potassium hydroxide, sodium chloride, ferrous sulphate, zinc sulphate, calcium carbonate, cupric sulphate, potassium iodide, manganese sulphate, sodium selenite), VITAMINS (ascorbic acid, choline chloride, choline bitartrate, M-inositol, DL-alpha tocopheryl acetate, niacinamide, calcium D-pantothenate, vitamin A palmitate, thiamine chloride hydrochloride, pyridoxine hydrochloride, ribofl avin, folic acid, phylloquinone, biotin, vitamin D3, cyanocobalamin). Contains: Milk, Soy.

SIMILAC® SENSITIVE®

LACTOSE SENSITIVITYFormula with lactose-free carbohydrate source†

For term infants 0+ months of age

Values listed are subject to change. Please refer to the product label or packaging for the most current ingredient, allergen and nutrient profi le information.

INGREDIENTSLISTCOMMODITY

#C6059-01 SEQ 15062

#C6064-02 SEQ 15064

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INDICATIONS FOR USE• For infants with symptoms of lactose intolerance such as

fussiness, gas, and/or diarrhea.1• For use as a breast milk substitute in infants who are not exclusively breastfed.• For oral or tube feeding use.Safety precautions:• Not for parenteral use.• Not for infants with galactosemia, congenital lactase defi ciency,

or confi rmed cow's milk protein allergy.2

FEATURES AND BENEFITS• Lactose-free carbohydrate source.†• Exclusive blend of DHA, lutein, and natural vitamin E.‡• DHA, an Omega-3 fat that supports the normal physical develop-

ment of the brain and eyes.3• Lutein, an antioxidant found in breast milk and concentrated in the

infant brain and eyes.4-6

- Recent studies show that lutein may have a role in visual and cognitive development.7• Vitamin E, a dietary antioxidant that protects fats in body tissues,

like DHA, from oxidation.3 - Similac® Sensitive® Lactose Sensitivity exclusively uses natural vitamin E,‡ the most abundant form found in breast milk and in the infant brain.8-11

• Non-GMO.§• Easy to digest.¶

TECHNICAL DATAReady to use

Caloric density (Cal/mL) 0.68Protein (% of total energy) 8.8Fat (% of total energy) 48.7Carbohydrate (% of total energy) 42.5Total Cal:g nitrogen ratio 291.4:1Non-protein Cal:g nitrogen ratio 265.9:1

Water (g/L) 875Osmolality (mOsm/kg water) 200Renal solute load (mOsm/L) 136Minimum tube size for gravity/pump feeding (Fr)

N/A

Low residue YesGluten-free YesKosher YesHalal Yes

AVAILABILITYReady to use66360871 Similac® Sensitive® 59-mL 48/case Lactose Sensitivity plastic bottles

† Contains inherent lactose from protein source.‡ RRR-a-tocopherol, provided as d-a-tocopheryl acetate, the most bioactive form of vitamin E. § Ingredients not genetically engineered.¶ Similar to other infant formulas. REFERENCES:1. Lasekan JB et al. Clin Pediatr 2011;50(4):330-7. 2. Health Canada, Canadian Paediatric Society, Dietitians of Canada, and Breastfeeding Committee for Canada (2015). Nutrition for healthy term infants: Recommendations from birth to six months. Last modifi ed 2015-08-18. [Accessed online 2021-07-08]. 3. Canadian Food Inspection Agency: Health Claims – Nutrient Function Claims. Last modified on 2019-10-31. [Accessed online on 2021-07-08]. 4. Zimmer JP et al. Clin Ophtalmol 2007;1:25-35. 5. Krinsky NI et al. Ann Rev Nutr 2003;23:171-201. 6. Vishwanathan R et al. JPGN 2014;59(5);659-65. 7. Johnson EJ. Nutr Rev 2014;72(9):605-12. 8. Stone WL et al. Am J Clin Nutr 2003;77:899-906. 9. Institute of Medicine (US) Panel on Dietary Antioxidants and Related Compounds. Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids. Washington (DC): National Academies Press (US);2000. 10. Kuchan MJ et al. Br J Nutr 2016;116(1):126-31. 11. Kuchan MJ et al. Curr Dev Nutr 2018;2:nzy055.

SIMILAC® SENSITIVE®

LACTOSE SENSITIVITY Formula with lactose-free carbohydrate source†

For term infants 0+ months of age

Exclusive blend ofDHA, lutein, andnatural vitamin E‡

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Per 100 mL Per 100 CalENERGY (Cal [kJ]) 68 (283) 100 (418)PROTEIN (g) 1.48 2.19% of total energy 8.8 Tryptophan (mg) 20.4 30.0 Taurine (mg) 4.5 6.7 Carnitine (mg) 0.82 1.2Nucleotides (mg) 7.20 10.7Source Milk protein isolateFAT (g) 3.66 5.41% of total energy 48.7 Linoleic Acid (g) 0.550 0.814 Arachidonic Acid (ARA) (g) 0.017 0.025 Linolenic Acid (g) 0.051 0.075 Docosahexaenoic Acid (DHA) (g) 0.011 0.017 Omega-6:Omega-3 ratio 8.06:1Source High oleic saffl ower oil, soy oil, coconut oilMCT oil (% of total fats) 0.0CARBOHYDRATE (g) 7.01 10.4% of total energy 42.5 Fibre (g) - - Short-chain fructooligosac-

charides (scFOS) (g)- -

Galactooligosaccharides (GOS) (g) - -Source Corn maltodextrin, sucroseAcesulfame-potassium (mg) - -Sucralose (mg) - -

VITAMINSVitamin A (IU) 200 296Vitamin D (IU) 40 59Vitamin E (IU) 1.7 2.5Vitamin K (mg) 0.0064 0.0095Vitamin C (mg) 9.0 13.0Thiamine (mg) 0.065 0.096Ribofl avin (mg) 0.100 0.148Niacin (mg) 0.45 0.67Vitamin B6 (mg) 0.050 0.074Folic acid (mg) 0.010 0.015Vitamin B12 (mg) 0.00030 0.00044Pantothenic acid (mg) 0.30 0.444Biotin (mg) 0.0025 0.0037Choline (mg) 8.2 12.0Inositol (mg) 3.8 5.6Lutein (mg) 0.0075 0.011

MINERALSSodium (mg) 20 30Potassium (mg) 72 107Chloride (mg) 44 65Calcium (mg) 57 84Phosphorus (mg) 36 53Magnesium (mg) 4.1 6.1Iron (mg) 1.1 1.6Zinc (mg) 0.40 0.59Iodine (mg) 0.009 0.013Copper (mg) 0.043 0.064Manganese (mg) 0.007 0.010Selenium (mg) 0.0008 0.0012Chromium (mg) - -Molybdenum (mg) - -

INGREDIENTSSimilac® Sensitive® Lactose Sensitivity, Ready to use: Water, Corn maltodextrin, Sucrose, Milk protein isolate, High oleic saffl ower oil, Soy oil, Coconut oil, Tricalcium phosphate, Potassium citrate, Carrageenan, Potassium chloride, Ascorbic acid, M. alpina oil (a source of ARA), Magnesium chloride, Monoglycerides, Soy lecithin, C. cohnii oil (a source of DHA), Potassium hydroxide, Choline chloride, Choline bitartrate, Taurine, M-inositol, Ferrous sulphate, Cytidine 5'-monophosphate, L-tryptophan, Disodium guanosine 5'-monophosphate, D-alpha tocopheryl acetate, Disodium uridine 5'-monophosphate, Adenosine 5'-monophosphate, Zinc sulphate, L-carnitine, Niacinamide, Calcium D-pantothenate, Ribofl avin, Vitamin A palmitate, Thiamine chloride hydrochloride, Copper sulphate, Pyridoxine hydrochloride, Manganese sulphate, Potassium iodide, Folic acid, Lutein, Phylloquinone, Beta-carotene, D-biotin, Sodium selenite, Vitamin D3, Cyanocobalamin. As needed: Sodium citrate, Magnesium phosphate. Contains: Milk, Soy.

Values listed are subject to change. Please refer to the product label or packaging for the most current ingredient, allergen and nutrient profi le information.

SIMILAC® SENSITIVE®

LACTOSE SENSITIVITY Formula with lactose-free carbohydrate source†

For term infants 0+ months of age

INGREDIENTS LISTAS PER COMMODITY

C6170-01

SEQ 15214

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SIMILAC® ISOMIL®

Soy protein-based formula with DHAFor infants 0+ months of age

INDICATIONS FOR USE• For use as a breast milk substitute in infants who are not exclusively breastfed.• For infants who cannot consume dairy-based products for health,

cultural, or religious reasons.1• For infants with a diagnosed IgE-mediated cow’s milk allergy where

tolerance to soy has been established.1,2

• For infants with congenital lactase deficiency.1• For infants with galactosemia.1• For oral or tube feeding use.Safety precaution:• Not for parenteral use.FEATURES AND BENEFITS• Soy protein-based, cow's milk protein-free.• DHA, the most abundant Omega-3 fatty acid in the brain and eyes.3• Naturally lactose-free.• Growth similar to that of infants fed breast milk or milk-based Similac®.4†

• Non-GMO.‡• Easy to digest.§

TECHNICAL DATAPowder

(at standard dilution)

Caloric density (Cal/mL) 0.66Protein (% of total energy) 10.0Fat (% of total energy) 48.0Carbohydrate (% of total energy) 42.0Total Cal:g nitrogen ratio 251:1Non-protein Cal:g nitrogen ratio 226:1

Water (g/L) 901Osmolality (mOsm/kg water) 200Renal solute load (mOsm/L) 162Minimum tube size for gravity/pump feeding (Fr) N/A

Low residue YesGluten-free YesKosher YesHalal Yes

AVAILABILITYPowder0S571353 Similac® Isomil® 800-g cans 6/case

† Comparison based on previous formulations of Similac® Step 1 and Similac® Isomil®.‡ Ingredients not genetically engineered.§ Similar to other infant formulas.REFERENCES:1. Health Canada, Canadian Paediatric Society, Dietitians of Canada, and Breastfeeding Committee for Canada (2015). Nutrition for healthy term infants: Recommendations from birth to six months. Last modifi ed 2015-08-18. [Accessed online 2021-07-08]. 2. Leung A, Otley A. Paediatr Child Health 2009;14(2):109-18. [Reaffi rmed Feb. 25, 2019]. 3. Calder PC. Ann Nutr Metab 2016;69(Suppl. 1):8-21. 4. Lasekan JB et al. Clin Pediatr 1999;38:563-71.

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ENERGY (Cal [kJ]) 504.6 (2111.3) 66 (278) PROTEIN (g) 12.30 1.62% of total energy 10.0 Methionine (mg) 240 32 Tryptophan (mg) 170 22 Taurine (mg) 30.6 4.0 Carnitine (mg) 6.9 0.91Nucleotides (mg) - - Source Soy protein isolateFAT (g) 26.60 3.50% of total energy 48.0 Linoleic Acid (g) 3.8 0.50 Arachidonic Acid (ARA) (g) 0.0666 0.0088 Linolenic Acid (g) 0.304 0.040 Docosahexaenoic Acid (DHA) (g) 0.0507 0.0067 Omega-6:Omega-3 ratio 9.1:1Source High oleic sunfl ower oil, coconut oil, soy oil,

M. alpina oil and C. cohnii oilMCT oil (% of total fats) 0.0CARBOHYDRATE (g) 54.00 7.10% of total energy 42.0 Fibre (g) - - Short-chain fructooligosac-

charides (scFOS) (g)- -

Galactooligosaccharides (GOS) (g) - -Source Corn syrup, sucroseAcesulfame-potassium (mg) - -Sucralose (mg) - -

VITAMINSVitamin A (IU) 1530 201Vitamin D (IU) 259 34Vitamin E (IU) 11.3 1.5Vitamin K (mg) 0.042 0.0055Vitamin C (mg) 58 7.6Thiamine (mg) 0.44 0.06Ribofl avin (mg) 0.47 0.06Niacin (mg) 4.3 0.57Vitamin B6 (mg) 0.27 0.04Folic acid (mg) 0.068 0.0089Vitamin B12 (mg) 0.00117 0.00015Pantothenic acid (mg) 3.4 0.45Biotin (mg) 0.017 0.0022Choline (mg) 62 8.2Inositol (mg) 81 10.7Lutein (mg) - -

MINERALSSodium (mg) 219 29Potassium (mg) 520 68Chloride (mg) 404 53Calcium (mg) 479 63Phosphorus (mg) 342 45Magnesium (mg) 37 4.9Iron (mg) 5.2 0.68Zinc (mg) 5.4 0.71Iodine (mg) 0.068 0.0089Copper (mg) 0.321 0.042Manganese (mg) 0.27 0.04Selenium (mg) 0.0117 0.0015Chromium (mg) - -Molybdenum (mg) - -

INGREDIENTSSimilac® Isomil®, Powder:Corn syrup, Soy protein isolate, High oleic sunfl ower oil, Sucrose, Coconut oil, Soy oil, Calcium phosphate, Potassium citrate, Soy lecithin, Sodium chloride, Potassium chloride, Magnesium chloride, M. alpina oil (a source of ARA), C. cohnii oil (a source of DHA), L-methionine, M-inositol, Ascorbic acid, Choline chloride, Taurine, Ascorbyl palmitate, L-tryptophan, Zinc sulphate, Ferrous sulphate, L-carnitine, Mixed tocopherols, Niacinamide, Calcium D-pantothenate, D-alpha-tocopheryl acetate, Vitamin A palmitate, Ribofl avin, Thiamine hydrochloride, Cupric sulphate, Pyridoxine hydrochloride, Potassium iodide, Folic acid, Phylloquinone, Sodium selenite, Biotin, Vitamin D3, Cyanocobalamin. As needed: Calcium carbonate, Potassium phosphate, Sodium citrate, Manganese sulphate. Contains: Soy.

Values listed are subject to change. Please refer to the product label or packaging for the most current ingredient, allergen and nutrient profi le information.

SIMILAC® ISOMIL®Soy protein-based formula with DHAFor infants 0+ months of age

INGREDIENTS LISTPOWDER COMMODITY #C102-339-002

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INDICATIONS FOR USE• For use as a breast milk substitute in infants who are not exclusively

breastfed.• For infants who cannot consume dairy-based products for health,

cultural, or religious reasons.1• For infants with a diagnosed IgE-mediated cow’s milk allergy where

tolerance to soy has been established.1,2

• For infants with congenital lactase deficiency.1• For infants with galactosemia.1• For oral or tube feeding use.Safety precautions:• Not for parenteral use.• For infants with galactosemia, Similac® Isomil® powder is the

preferred format.

FEATURES AND BENEFITS• Soy protein-based, cow's milk protein-free.• Exclusive blend of DHA, lutein, and natural vitamin E.†• DHA, an Omega-3 fat that supports the normal physical develop-

ment of the brain and eyes.3 • Lutein, an antioxidant found in breast milk and concentrated in the

infant brain and eyes.4-6

- Recent studies show that lutein may have a role in visual and cognitive development.7

• Vitamin E, an antioxidant found in breast milk.3 - Similac® Isomil® exclusively uses natural vitamin E,† the most

abundant form found in breast milk and in the infant brain.8-11

• Naturally lactose-free.• Growth similar to that of infants fed breast milk or milk-based Similac®.12‡

• Non-GMO.§• Easy to digest.¶

TECHNICAL DATAReady to use

Caloric density (Cal/mL) 0.68Protein (% of total energy) 9.8Fat (% of total energy) 49.0Carbohydrate (% of total energy) 41.2Total Cal:g nitrogen ratio 255:1Non-protein Cal:g nitrogen ratio 230:1

Water (g/L) 875Osmolality (mOsm/kg water) 200Renal solute load (mOsm/L) 156Minimum tube size for gravity/pump feeding (Fr)

N/A

Low residue YesGluten-free YesKosher YesHalal Yes

AVAILABILITYReady to use66475871 Similac® Isomil® 59-mL 48/case plastic bottles

† RRR-a-tocopherol, provided as d-a-tocopheryl acetate, the most bioactive form of vitamin E.‡ Comparison based on previous formulations of Similac® Step 1 and Similac® Isomil®.§ Ingredients not genetically engineered.¶ Similar to other infant formulas. REFERENCES:1. Health Canada, Canadian Paediatric Society, Dietitians of Canada, and Breastfeeding Committee for Canada (2015). Nutrition for healthy term infants: Recommendations from birth to six months. Last modifi ed 2015-08-18. [Accessed online 2021-07-08]. 2. Leung A, Otley A. Paediatric Child Health 2009;14(3):109-18. [Reaffirmed: Feb. 25, 2019]. 3. Canadian Food Inspection Agency: Health Claims – Nutrient Function Claims. Last modified on 2019-10-31. [Accessed online on 2021-07-08]. 4. Zimmer JP et al. Clin Ophtalmol 2007;1:25-35. 5. Krinsky NI et al. Ann Rev Nutr 2003;23:171-201. 6. Vishwanathan R et al. JPGN 2014;59(5):659-65. 7. Johnson EJ. Nutrition Reviews 2014;72(9):605-12. 8. Stone WL et al. Am J Clin Nutr 2003;77:899-906. 9. Institute of Medicine. Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium and Carotenoids. National Academy of Sciences. 2000. 10. Kuchan MJ et al. Br J Nutr 2016;116(1):126-31. 11. Kuchan MJ et al. Curr Dev Nutr 2018;2:nzy055. 12. Lasekan JB et al. Clin Pediatr 1999;38:563-71.

SIMILAC® ISOMIL®

Soy protein-based formula with DHAFor infants 0+ months of age

Exclusive blend ofDHA, lutein, andnatural vitamin E†

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Per 100 mL Per 100 CalENERGY (Cal [kJ]) 68 (283) 100 (418)PROTEIN (g) 1.66 2.46% of total energy 9.8 Methionine (mg) 19.0 28.1 Tryptophan (mg) 23.0 34.0 Taurine (mg) 4.1 6.1 Carnitine (mg) 0.80 1.20Nucleotides (mg) - -Source Soy protein isolateFAT (g) 3.68 5.44% of total energy 49.0 Linoleic Acid (g) 0.670 0.991 Arachidonic Acid (ARA) (g) 0.017 0.025 Linolenic Acid (g) 0.051 0.075 Docosahexaenoic Acid (DHA) (g) 0.011 0.017 Omega-6:Omega-3 ratio 8.13:1Source High oleic saffl ower oil, soy oil, coconut oil,

M. alpina oil and C. cohnii oilMCT oil (% of total fats) 0.0CARBOHYDRATE (g) 6.96 10.3% of total energy 41.2 Fibre (g) - - Short-chain fructooligosac-

charides (scFOS) (g)- -

Galactooligosaccharides (GOS) (g) - -Source Corn syrup, sucroseAcesulfame-potassium (mg) - -Sucralose (mg) - -

VITAMINSVitamin A (IU) 189 280Vitamin D (IU) 36 53Vitamin E (IU) 2.0 3.0Vitamin K (mg) 0.0064 0.0095Vitamin C (mg) 7.9 11.7Thiamine (mg) 0.052 0.077Ribofl avin (mg) 0.055 0.081Niacin (mg) 0.57 0.84Vitamin B6 (mg) 0.040 0.059Folic acid (mg) 0.009 0.013Vitamin B12 (mg) 0.00027 0.00040Pantothenic acid (mg) 0.45 0.67Biotin (mg) 0.0027 0.0040Choline (mg) 8.2 12.1Inositol (mg) 2.8 4.1Lutein (mg) 0.0075 0.0111

MINERALSSodium (mg) 27 40Potassium (mg) 92 136Chloride (mg) 40 59Calcium (mg) 63 93Phosphorus (mg) 45 67Magnesium (mg) 4.5 6.7Iron (mg) 1.1 1.6Zinc (mg) 0.45 0.67Iodine (mg) 0.009 0.013Copper (mg) 0.045 0.067Manganese (mg) 0.023 0.034Selenium (mg) 0.0014 0.0021Chromium (mg) - -Molybdenum (mg) - -

INGREDIENTSSimilac® Isomil®, Ready to use: Water, Corn syrup, Soy protein isolate, High oleic saffl ower oil, Sucrose, Soy oil, Coconut oil, Calcium citrate, Potassium phosphate, Calcium phosphate, Ascorbic acid, M. alpina oil (a source of ARA), Sodium citrate, Potassium hydroxide, Magnesium chloride, Monoglycerides, Soy lecithin, Potassium chloride, C. cohnii oil (a source of DHA), L-methionine, Choline bitartrate, Potassium citrate, Carrageenan, L-tryptophan, Taurine, Ferrous sulphate, M-inositol, Zinc sulphate, D-alpha tocopheryl acetate, L-carnitine, Calcium D-pantothenate, Niacinamide, Vitamin A palmitate, Cupric sulphate, Ribofl avin, Thiamine chloride hydrochloride, Pyridoxine hydrochloride, Manganese sulphate, Potassium iodide, Lutein, Folic acid, Phylloquinone, Beta-carotene, Sodium selenate, D-biotin, Vitamin D3, Cyanocobalamin. As needed: Sodium chloride. Contains: Soy.

Values listed are subject to change. Please refer to the product label or packaging for the most current ingredient, allergen and nutrient profi le information.

SIMILAC® ISOMIL®

Soy protein-based formula with DHAFor infants 0+ months of age

INGREDIENTS LISTAS PER COMMODITY

#C6280-01

Seq 15223

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SIMILAC® 24 Hypercaloric, DHA- and ARA-enriched formulaFor term infants 0+ months of age

INDICATIONS FOR USE• For infants with increased caloric needs.• For volume-restricted infants.• For oral or tube feeding use.• Use under medical supervision.Safety precaution:• Not for parenteral use.

FEATURES AND BENEFITS• Increased caloric density: provides 81 Cal/100 mL (24 Cal/30 mL).• DHA, an Omega-3 fatty acid that supports the normal physical development of the brain and eyes.1• Lutein, an antioxidant found in breast milk and concentrated in the infant brain and eyes.2-4

- Recent studies show that lutein may have a role in visual and cognitive development.5• Vitamin E, an antioxidant found in breast milk.6,7

- Similac® 24 exclusively uses natural vitamin E,† the most abundant form found in breast milk and in the infant brain.8,9

• Easy to digest.‡

TECHNICAL DATAReady to use

Caloric density (Cal/mL) 0.81Protein (% of total energy) 8.1Fat (% of total energy) 49.5Carbohydrate (% of total energy) 42.4Total Cal:g nitrogen ratio 314:1Non-protein Cal:g nitrogen ratio 288:1

Water (g/L) 844Osmolality (mOsm/kg water) 375Renal solute load (mOsm/L) 156Minimum tube size for gravity/pump feeding (Fr)

N/A

Low residue YesGluten-free YesKosher YesHalal Yes

AVAILABILITYReady to use66359871 Similac® 24 59-mL 48/case plastic bottles

† RRR-a-tocopherol, provided as d-a-tocopheryl acetate, the most bioactive form of vitamin E.‡ Similar to other infant formulas.REFERENCES:1. Canadian Food Inspection Agency: Health Claims – Nutrient Function Claims. Last modified on 2019-10-31. [Accessed online on 2021-07-08]. 2. Zimmer JP et al. Clin Ophtalmol 2007;1:25-35. 3. Krinsky NI et al. Ann Rev Nutr 2003;23:171-201. 4. Vishwanathan R et al. JPGN 2014;59(5);659-65. 5. Johnson EJ. Nutrition Reviews 2014;72(9):605-12. 6. Stone WL et al. Am J Clin Nutr 2003;77:899-906. 7. Institute of Medicine. Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium and Carotenoids. National Academy of Sciences. 2000. 8. Kuchan MJ et al. Curr Dev Nutr 2018;2:nzy055. 9. Kuchan MJ et al. Br J Nutr 2016;116(1):126-31.

Exclusive blend ofDHA, lutein, andnatural vitamin E†

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SIMILAC® 24Hypercaloric, DHA- and ARA-enriched formulaFor term infants 0+ months of age

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Per 100 mL Per 100 CalENERGY (Cal [kJ]) 81 (340) 100 (418)PROTEIN (g) 1.65 2.03% of total energy 8.1 Tryptophan (mg) 26.8 33.0 Taurine (mg) 5.4 6.7 Carnitine (mg) 1.0 1.2Nucleotides (mg) 7.2 8.9Source Dry or evaporated skim milk, whey protein concentrateFAT (g) 4.46 5.50% of total energy 49.5 Linoleic Acid (g) 0.706 0.870 Arachidonic Acid (ARA) (g) 0.020 0.025 Linolenic Acid (g) 0.068 0.084 Docosahexaenoic Acid (DHA) (g) 0.014 0.017 Omega-6:Omega-3 ratio 8.1:1Source High oleic saffl ower oil, soy oil, coconut oil, ARA and DHAMCT oil (% of total fats) 0.0CARBOHYDRATE (g) 8.60 10.6% of total energy 42.4 Fibre (g) - - Short-chain fructooligosac-

charides (scFOS) (g)- -

Galactooligosaccharides (GOS) (g) - -Source LactoseAcesulfame-potassium (mg) - -Sucralose (mg) - -

VITAMINSVitamin A (IU) 240 296Vitamin D (IU) 42 52Vitamin E (IU) 3.0 3.7Vitamin K (mg) 0.0100 0.0123Vitamin C (mg) 12.2 15.0Thiamine (mg) 0.078 0.096Ribofl avin (mg) 0.140 0.173Niacin (mg) 0.54 0.67Vitamin B6 (mg) 0.057 0.070Folic acid (mg) 0.010 0.012Vitamin B12 (mg) 0.00028 0.00035Pantothenic acid (mg) 0.48 0.59Biotin (mg) 0.0036 0.0044Choline (mg) 13.0 16.0Inositol (mg) 4.8 5.9Lutein (mg) 0.0075 0.0092

MINERALSSodium (mg) 22 27Potassium (mg) 95 117Chloride (mg) 53 65Calcium (mg) 64 79Phosphorus (mg) 34 42Magnesium (mg) 6.0 7.4Iron (mg) 1.46 1.80Zinc (mg) 0.56 0.69Iodine (mg) 0.011 0.014Copper (mg) 0.056 0.069Manganese (mg) 0.0041 0.0051Selenium (mg) 0.0016 0.0020Chromium (mg) - -Molybdenum (mg) - -

INGREDIENTSSimilac® 24, Ready to use:Water, Lactose, Dry or evaporated skim milk, High oleic saffl ower oil, Soy oil, Coconut oil, Whey protein concentrate, Ascorbic acid, M. alpina oil (a source of ARA), Calcium carbonate, Potassium citrate, C. cohnii oil (a source of DHA), Monoglycerides, Soy lecithin, Sodium citrate, Potassium chloride, Magnesium chloride, Calcium phosphate, Carrageenan, Potassium phosphate, Choline chloride, Taurine, Ferrous sulphate, Choline bitartrate, M-inositol, Cytidine 5'-monophosphate, Citric acid, L-tryptophan, D-alpha tocopheryl acetate, Disodium guanosine 5'-monophosphate, Disodium uridine 5'-monophosphate, Zinc sulphate, Adenosine 5'-monophosphate, Niacinamide, Calcium D-pantothenate, L-carnitine, Vitamin A palmitate, Cupric sulphate, Thiamine chloride hydrochloride, Ribofl avin, Pyridoxine hydrochloride, Manganese sulphate, Lutein, Folic acid, Phylloquinone, Beta-carotene, Biotin, Sodium selenite, Vitamin D3, Cyanocobalamin. As needed: Magnesium sulphate, Sodium chloride, Potassium iodide. Contains: Milk, Soy.

Values listed are subject to change. Please refer to the product label or packaging for the most current ingredient, allergen and nutrient profi le information.

INGREDIENTS LISTAS PER COMMODITY #C5881-03SEQ 15113

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SIMILAC® ALIMENTUM®

Hypoallergenic,† extensively hydrolyzed formulaFor infants 0+ months of age

INDICATIONS FOR USE• For infants with: - Food allergies;1 - Colic symptoms due to protein sensitivity (cow’s milk and/or soy protein);2,3 - Sensitivity to intact protein (cow’s milk and/or soy protein);1 - Malabsorption syndromes.1 • For use as a breast milk substitute in term infants whose health care professional recommends the use of an extensively hydrolyzed formula.• For oral or tube feeding use.Safety precautions:• Not for parenteral use.• Not for infants with galactosemia.

FEATURES AND BENEFITS• Clinically proven to be hypoallergenic† in children with milk

allergy.4,5‡

• Extensively hydrolyzed casein supplemented with free amino acids to minimize the potential for allergic reaction.

• Lactose-free carbohydrate.• DHA, the most abundant Omega-3 fatty acid in the brain and eyes.6• Approximately 33% of fat as medium chain triglycerides, an easily

digested and well-absorbed fat source.7• Easy to digest.§

TECHNICAL DATAPowder

(at standard dilution)

Caloric density (Cal/mL) 0.68Protein (% of total energy) 11.0Fat (% of total energy) 48.6Carbohydrate (% of total energy) 40.4Total Cal:g nitrogen ratio 230:1Non-protein Cal:g nitrogen ratio 205:1

Water (g/L) 892Osmolality (mOsm/kg water) 274Renal solute load (mOsm/L) 171Minimum tube size for gravity/pump feeding (Fr)

N/A

Low residue YesGluten-free YesKosher NoHalal No

AVAILABILITYPowder57077340 Similac® Alimentum® 400-g cans 6/case

† Hypoallergenic does not mean non-allergenic.‡ Studied before the addition of DHA and ARA.§ Similar to other infant formulas.REFERENCES:1. Health Canada, Canadian Paediatric Society, Dietitians of Canada, and Breastfeeding Committee for Canada (2015). Nutrition for healthy term infants: Recommendations from birth to six months. Last modifi ed 2015-08-18. [Accessed online 2021-07-08]. 2. Critch JN. Paediatr Child Health 2011;16(1):47-9. [Reaffirmed Feb. 28, 2018]. 3. Jakobsson I et al. Acta Paediatrica 2000;89:18-21. 4. Sampson HA et al. Safety of Casein Hydrolysate Formula in Children with Cow Milk Allergy. J Pediatrics 1991;118(4):520-5. 5. Borschel M, Burks AW Jr. Double-blind, placebo-controlled, food challenges (DBPCFC) of a strong tasting food: lessons learned. Clinical and Translational Allergy 2014;4(Suppl 1):95. 6. Calder PC. Ann Nutr Metab 2016;69(Suppl. 1):8-21. 7. Duggan C et al. Nutrition in Pediatrics: Standard and Specialized Enteral Formulas. BC Decker Inc. Hamilton. 2008.

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SIMILAC® ALIMENTUM®

Hypoallergenic, extensively hydrolyzed formulaFor infants 0+ months of age

NU

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Per 100 gPowder

Per 100 mL(at standard

dilution) Per 100 CalENERGY (Cal [kJ]) 517 (2163) 67.6 (283) 100 (418)PROTEIN (g) 14.21 1.86 2.75% of total energy 11.0 Cystine (mg) 196 26.0 38 Tyrosine (mg) 310 41.0 77 Tryptophan (mg) 171 22.0 33 Taurine (mg) 30.0 3.92 5.8 Carnitine (mg) 10.3 1.35 2.0Nucleotides (mg) - - -Source Casein hydrolysate, free amino acidsFAT (g) 28.63 3.80 5.54% of total energy 48.6 Linoleic Acid (g) 4.135 0.540 0.800 Arachidonic Acid (ARA) (g) 0.101 0.0130 0.0195 Linolenic Acid (g) 0.439 0.0580 0.0850 Docosahexaenoic Acid (DHA) (g) 0.051 0.0070 0.00986 Omega-6:Omega-3 ratio 9.44:1Source High oleic saffl ower oil, MCT oil, soy oil, ARA and DHAMCT oil (% of total fats) 33CARBOHYDRATE (g) 52.20 6.80 10.1% of total energy 40.4 Fibre (g) - - - Short-chain fructooligosac-

charides (scFOS) (g)- - -

Galactooligosaccharides (GOS) (g) - - -Source Corn maltodextrin, sucrose, modifi ed corn starchAcesulfame-potassium (mg) - - -Sucralose (mg) - - -

VITAMINSVitamin A (IU) 1550 203 300Vitamin D (IU) 310 41.0 60Vitamin E (IU) 15.5 2.00 3.00Vitamin K (mg) 0.0517 0.00680 0.0100Vitamin C (mg) 64.6 8.50 12.5Thiamine (mg) 0.388 0.0510 0.0751Ribofl avin (mg) 0.517 0.0680 0.100Niacin (mg) 5.43 0.710 1.051Vitamin B6 (mg) 0.310 0.0410 0.0600Folic acid (mg) 0.0775 0.0100 0.0150Vitamin B12 (mg) 0.00181 0.000240 0.000350Pantothenic acid (mg) 3.88 0.510 0.751Biotin (mg) 0.0233 0.00300 0.00451Choline (mg) 77.5 10.1 15.0Inositol (mg) 31.0 4.10 6.00Lutein (mg) - - -

MINERALSSodium (mg) 227 30.0 43.9Potassium (mg) 610 80.0 118Chloride (mg) 413 54.0 80Calcium (mg) 543 71.0 105Phosphorus (mg) 388 51.0 75.1Magnesium (mg) 38.8 5.10 7.51Iron (mg) 9.30 1.22 1.80Zinc (mg) 3.88 0.510 0.751Iodine (mg) 0.0780 0.0100 0.0151Copper (mg) 0.388 0.0510 0.0751Manganese (mg) 0.0362 0.00473 0.0070Selenium (mg) 0.0109 0.00140 0.00211Chromium (mg) - - -Molybdenum (mg) - - -

INGREDIENTSSimilac® Alimentum®, Powder:Corn maltodextrin, Casein hydrolysate (milk), High oleic saffl ower oil, Modifi ed coconut and/or palm kernel oils (medium chain triglycerides), Sucrose, Soy oil, Modifi ed corn starch, Calcium citrate, Calcium phosphate, Potassium citrate, Xanthan gum, Potassium phosphate, M. alpina oil (a source of ARA), L-tyrosine, Magnesium chloride, L-cystine hydrochloride, Sodium chloride, Ascorbic acid, C. cohnii oil (a source of DHA), L-tryptophan, Choline chloride, Ferrous sulphate, Potassium chloride, Taurine, M-inositol, DL-alpha-tocopheryl acetate, Ascorbyl palmitate, Zinc sulphate, L-carnitine, Mixed tocopherols, Niacinamide, Calcium D-pantothenate, Cupric sulphate, Vitamin A palmitate, Ribofl avin, Thiamine chloride hydrochloride, Pyridoxine hydrochloride, Folic acid, Potassium iodide, Phylloquinone, D-biotin, Sodium selenite, Vitamin D3, Cyanocobalamin. As needed: Potassium hydroxide, Citric acid, Manganese sulphate.

Values listed are subject to change. Please refer to the product label or packaging for the most current ingredient, allergen and nutrient profi le information.

INGREDIENTSLISTAS PER COMMODITY

C6054-01

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SIMILAC® ALIMENTUM®

Hypoallergenic,† extensively hydrolyzed formulaFor infants 0+ months of age

INDICATIONS FOR USE• For infants with: - Food allergies;1 - Colic symptoms due to protein sensitivity (cow’s milk and/or soy

protein);2,3

- Sensitivity to intact protein (cow’s milk and/or soy protein);1 - Malabsorption syndromes.1 • For use as a breast milk substitute in term infants whose health care

professional recommends the use of an extensively hydrolyzed formula.

• For oral or tube feeding use.Safety precautions:• Not for parenteral use.• Not for infants with galactosemia.

FEATURES AND BENEFITS• Clinically proven to be hypoallergenic† in children with milk

allergy.4,5‡

• Extensively hydrolyzed casein supplemented with free amino acids to minimize the potential for allergic reaction.

• Lactose-free carbohydrate.• Approximately 33% of fat as medium chain triglycerides,

an easily digested and well-absorbed fat source.6• Easy to digest.§

TECHNICAL DATAReady to use

Caloric density (Cal/mL) 0.68Protein (% of total energy) 11Fat (% of total energy) 49Carbohydrate (% of total energy) 40Total Cal:g nitrogen ratio N/ANon-protein Cal:g nitrogen ratio N/A

Water (g/L) 900Osmolality (mOsm/kg water) 370Renal solute load (mOsm/L) 123Minimum tube size for gravity/pump feeding (Fr)

N/A

Low residue YesGluten-free YesKosher NoHalal No

AVAILABILITYReady to use58266941 Similac® Alimentum® 237-mL cans 6 x 4/case

† Hypoallergenic does not mean non-allergenic.‡ Studied before the addition of DHA and ARA.§ Similar to other infant formulas.REFERENCES:1. Health Canada, Canadian Paediatric Society, Dietitians of Canada, and Breastfeeding Committee for Canada (2015). Nutrition for healthy term infants: Recommendations from birth to six months. Last modifi ed 2015-08-18. [Accessed online 2021-07-08]. 2. Critch JN. Paediatr Child Health 2011;16(1):47-9. [Reaffirmed Feb. 28, 2018]. 3. Jakobsson I et al. Acta Paediatrica 2000;89:18-21. 4. Sampson HA et al. Safety of Casein Hydrolysate Formula in Children with Cow Milk Allergy. J Pediatrics 1991;118(4):520-5. 5. Borschel M, Burks AW Jr. Double-blind, placebo-controlled, food challenges (DBPCFC) of a strong tasting food: lessons learned. Clinical and Translational Allergy 2014;4(Suppl 1):95. 6. Duggan C et al. Nutrition in Pediatrics: Standard and Specialized Enteral Formulas. BC Decker Inc. Hamilton. 2008.

IMAGEBANKBOX COM. #C5924-02

CAN COM. C5923-02

SEQ 15066 BOX

SEQ 15065 CAN

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SIMILAC® ALIMENTUM®

Hypoallergenic, extensively hydrolyzed formulaFor infants 0+ months of age

NU

TRITIO

NA

L INFO

RM

ATIO

NENERGY

Per 100 mL Per 100 CalENERGY (Cal [kJ]) 68 (285) 100 (418)PROTEIN (g) 1.86 2.75% of total energy 11 Cystine (mg) 28.9 46 Tyrosine (mg) 29.0 43 Tryptophan (mg) 27.7 38 Taurine (mg) 5.2 7.7 Carnitine (mg) 1.5 2.2 Source Casein hydrolysate, free amino acidsFAT (g) 3.75 5.55% of total energy 49 Linoleic Acid (g) 1.28 1.90 Arachidonic Acid (ARA) (g) - - Linolenic Acid (g) 0.075 0.110 Docosahexaenoic Acid (DHA) (g) - - Omega-6:Omega-3 ratio N/ASource Saffl ower oil, MCT oil, soy oilMCT oil (% of total fats) 33CARBOHYDRATE (g) 6.9 10.2% of total energy 40 Fibre (g) - - Short-chain fructooligosac-

charides (scFOS) (g)- -

Galactooligosaccharides (GOS) (g) - -Source Sucrose, modifi ed tapioca starchAcesulfame-potassium (mg) - -Sucralose (mg) - -

VITAMINSVitamin A (IU) 203 300Vitamin D (IU) 30 45Vitamin E (IU) 2.0 3.0Vitamin K (mg) 0.010 0.015Vitamin C (mg) 6.0 9.0Thiamine (mg) 0.041 0.060Ribofl avin (mg) 0.061 0.090Niacin (mg) 0.913 1.350Vitamin B6 (mg) 0.041 0.060Folic acid (mg) 0.01 0.015Vitamin B12 (mg) 0.0003 0.0004Pantothenic acid (mg) 0.507 0.750Biotin (mg) 0.003 0.005Choline (mg) 8.5 12.6Inositol (mg) 3.4 5.0

MINERALSSodium (mg) 30 44Potassium (mg) 80 118Chloride (mg) 54 80Calcium (mg) 71 105Phosphorus (mg) 51 75Magnesium (mg) 5.1 7.5Iron (mg) 1.2 1.8Zinc (mg) 0.51 0.75Iodine (mg) 0.01 0.01Copper (mg) 0.051 0.075Manganese (mg) 0.0054 0.0080Selenium (mg) 0.0019 0.0028Chromium (mg) - -Molybdenum (mg) - -

INGREDIENTSSimilac® Alimentum®, Ready to use: Water, Sucrose, Casein hydrolysate (milk), Modifi ed tapioca starch, Saffl ower oil, Modifi ed coconut and/or palm kernel oils (medium chain triglycerides), Soy oil, Calcium citrate, Calcium phosphate, Carrageenan, Potassium phosphate, Ascorbic acid, Magnesium chloride, Calcium hydroxide, Sodium chloride, Potassium chloride, L-cystine dihydrochloride, Potassium citrate, L-tyrosine, Choline chloride, L-tryptophan, Ferrous sulphate, Taurine, M-inositol, DL-alpha-tocopheryl acetate, Zinc sulphate, L-carnitine, Niacinamide, Calcium pantothenate, Vitamin A palmitate, Cupric sulphate, Thiamine chloride hydrochloride, Ribofl avin, Pyridoxine hydrochloride, Folic acid, Potassium iodide, Phylloquinone, Biotin, Sodium selenate, Vitamin D3, Cyanocobalamin.

Values listed are subject to change. Please refer to the product label or packaging for the most current ingredient, allergen and nutrient profi le information.

INGREDIENTSLISTAS PER BOXCOMMODITY#C5924-02 AND CAN COM. C5923-02

Page 86: 2021 PEDIATRIC NUTRITIONAL PRODUCTS GUIDE

SIMILAC® ALIMENTUM®

Hypoallergenic,† extensively hydrolyzed formulaFor infants 0+ months of age

INDICATIONS FOR USE• For infants with: - Food allergies;1 - Colic symptoms due to protein sensitivity (cow’s milk and/or

soy protein);2,3 - Sensitivity to intact protein (cow’s milk and/or soy protein);1 - Malabsorption syndromes.1 • For use as a breast milk substitute in term infants whose health care

professional recommends the use of an extensively hydrolyzed formula.

• For oral or tube feeding use.Safety precautions:• Not for parenteral use.• Not for infants with galactosemia.

FEATURES AND BENEFITS• Clinically proven to be hypoallergenic† in children with milk

allergy.4,5‡

• Extensively hydrolyzed casein supplemented with free amino acids to minimize the potential for allergic reaction.

• Lactose-free carbohydrate.• DHA, an Omega-3 fatty acid that supports the normal physical

development of the brain and eyes.6• Approximately 33% of fat as medium chain triglycerides, an easily

digested and well-absorbed fat source.7• Easy to digest.§• Corn-free.

TECHNICAL DATAReady to use

Caloric density (Cal/mL) 0.68Protein (% of total energy) 11Fat (% of total energy) 48Carbohydrate (% of total energy) 41Total Cal:g nitrogen ratio N/ANon-protein Cal:g nitrogen ratio N/A

Water (g/L) 899Osmolality (mOsm/kg water) 370Renal solute load (mOsm/L) 171Minimum tube size for gravity/pump feeding (Fr) N/A

Low residue YesGluten-free YesKosher NoHalal No

AVAILABILITYReady to use59738871 Similac® Alimentum® 59-mL plastic 48/case bottles

† Hypoallergenic does not mean non-allergenic.‡ Studied before the addition of DHA and ARA.§ Similar to other infant formulas.REFERENCES:1. Health Canada, Canadian Paediatric Society, Dietitians of Canada, and Breastfeeding Committee for Canada (2015). Nutrition for healthy term infants: Recommendations from birth to six months. Last modifi ed 2015-08-18. [Accessed online 2021-07-08]. 2. Critch JN. Paediatr Child Health 2011;16(1):47-9. [Reaffirmed Feb. 28, 2018]. 3. Jakobsson I et al. Acta Paediatrica 2000;89:18-21. 4. Sampson HA et al. Safety of Casein Hydrolysate Formula in Children with Cow Milk Allergy. J Pediatrics 1991;118(4):520-5. 5. Borschel M, Burks AW Jr. Double-blind, placebo-controlled, food challenges (DBPCFC) of a strong tasting food: lessons learned. Clinical and Translational Allergy 2014;4(Suppl 1):95. 6. Canadian Food Inspection Agency: Health Claims – Nutrient Function Claims. Last modified on 2019-10-31. [Accessed online on 2021-07-08]. 7. Duggan C et al. Nutrition in Pediatrics: Standard and Specialized Enteral Formulas. BC Decker Inc. Hamilton 2008.

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SIMILAC® ALIMENTUM®Hypoallergenic, extensively hydrolyzed formulaFor infants 0+ months of age

NU

TRITIO

NA

L INFO

RM

ATIO

NENERGY

Per 100 mL Per 100 CalENERGY (Cal [kJ]) 68 (283) 100 (419)PROTEIN (g) 1.86 2.75% of total energy 11 Cystine (mg) 19.0 29 Tyrosine (mg) 19.0 29 Tryptophan (mg) 21.0 32 Taurine (mg) 3.00 4.44 Carnitine (mg) 1.05 1.55 Source Casein hydrolysate, free amino acidsFAT (g) 3.75 5.54% of total energy 48 Linoleic Acid (g) 1.28 1.90 Arachidonic Acid (ARA) (g) 0.012 0.018 Linolenic Acid (g) 0.074 0.110 Docosahexaenoic Acid (DHA) (g) 0.005 0.0074 Omega-6:Omega-3 ratio N/ASource Saffl ower oil, MCT oil, soy oilMCT oil (% of total fats) 33CARBOHYDRATE (g) 6.9 10.2% of total energy 41 Fibre (g) - - Short-chain fructooligosac-

charides (scFOS) (g)- -

Galactooligosaccharides (GOS) (g) - -Source Sucrose, modifi ed tapioca starchAcesulfame-potassium (mg) - -Sucralose (mg) - -

VITAMINSVitamin A (IU) 203 300Vitamin D (IU) 30 45Vitamin E (IU) 2.0 3.0Vitamin K (mg) 0.010 0.015Vitamin C (mg) 6.0 9.0Thiamine (mg) 0.041 0.060Ribofl avin (mg) 0.061 0.090Niacin (mg) 0.913 1.35Vitamin B6 (mg) 0.041 0.060Folic acid (mg) 0.010 0.015Vitamin B12 (mg) 0.00030 0.00045Pantothenic acid (mg) 0.507 0.750Biotin (mg) 0.0030 0.0045Choline (mg) 8 12Inositol (mg) 3 5.0

MINERALSSodium (mg) 30 44Potassium (mg) 80 118Chloride (mg) 54 80Calcium (mg) 71 105Phosphorus (mg) 51 75Magnesium (mg) 5.1 7.5Iron (mg) 1.2 1.8Zinc (mg) 0.51 0.75Iodine (mg) 0.010 0.015Copper (mg) 0.051 0.075Manganese (mg) 0.005 0.008Selenium (mg) 0.0015 0.002Chromium (mg) - -Molybdenum (mg) - -

INGREDIENTSSimilac® Alimentum®, Ready to use:Water, Sucrose, Casein hydrolysate (milk), Modifi ed tapioca starch, Saffl ower oil, Modifi ed coconut and/or palm kernel oils (medium chain triglycerides), Soy oil, Calcium phosphate, Calcium citrate, Carrageenan, Potassium phosphate, Ascorbic acid, Magnesium chloride, M. alpina oil (a source of ARA), Sodium chloride, Calcium hydroxide, L-cystine dihydrochloride, Potassium chloride, Potassium citrate, C. cohnii oil (a source of DHA), L-tyrosine, L-tryptophan, Choline chloride, Ferrous sulphate, Taurine, M-inositol, DL-alpha-tocopheryl acetate, Zinc sulphate, L-carnitine, Niacinamide, Calcium D-pantothenate, Vitamin A palmitate, Copper sulphate, Thiamine chloride hydrochloride, Ribofl avin, Pyridoxine hydrochloride, Folic acid, Potassium iodide, Phylloquinone, D-biotin, Sodium selenate, Vitamin D3, Cyanocobalamin. As needed: Potassium hydroxide, Citric acid.

Values listed are subject to change. Please refer to the product label or packaging for the most current ingredient, allergen and nutrient profi le information.

INGREDIENTS LISTAS PER COMMODITY #C5920-01

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NOTES:

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Tod

dlers

and C

hildren

TODDLERS AND CHILDRENIN THIS SECTIONGo & Grow by Similac® Step 3Go & Grow by Similac® Step 3 (RTU)PediaSure Complete® Grow & Gain™PediaSure Complete® Grow & Gain™ Reduced SugarPediaSure®

PediaSure® FibrePediaSure® PlusPediaSure® Peptide 1 Cal

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dle

rs

and

Chi

ldre

n

TODDLERS AND CHILDREN

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LEARN ABOUT scFOS

WHAT ARE scFOS?

Short-chain fructooligosaccharides (scFOS) are non-digestible carbohydrates that are naturally found in common foods such as bananas, asparagus, and onions.1,2

scFOS are recognized as a source of dietary fi bre by Health Canada3 and are defi ned as prebiotics by the scientifi c community because they stimulate the growth of benefi cial intestinal bacteria.1

scFOS AND THE GASTROINTESTINAL TRACT

WHAT BENEFITS DO scFOS PROVIDE?

• scFOS can help your patients meet their daily fi bre requirements.3

• SCFAs are the preferred energy source for cells in the colon.4

Abbott nutritional products containing scFOS:Similac Pro-Advance® Step 1 Similac Pro-Advance® Step 2PediaSure® PlusPediaSure® Peptide 1 CalPediaSure Complete® Grow & Gain™Pedialyte® AdvancedCare® Plus Powder SticksEnsure® Protein MaxEnsure® PuddingGlucerna® Nutritional DrinkJevity® 1.2 CalJevity® 1.5 CalNepro®

Suplena®

TwoCal® HN

scFOS are not digested in the small intestine, remaining intact until they reach the colon, where they are fermented by benefi cial bacteria (such as bifi dobacteria and lactobacilli) to short-chain fatty acids (SCFAs).1,2,4

REFERENCES:1. Gibson GR et al. Selective stimulation of bifi dobacteria in the human colon by oligofructose and inulin. Gastroenterology 1995;108:975-82. 2. Cho SS, Finocchiaro ET (eds). Handbook of Prebiotics and Probi-otics Ingredients: Health Benefi ts and Food Applications. CRC Press, Taylor and Francis Group, 2010.3. Health Canada. List of Dietary Fibres Permitted for Use in Foods Available for Sale in Canada,September 2013. 4. Topping DL, Clifton PM. Physiological Reviews 2001;81(3):1031-64.

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GO & GROW BY SIMILAC®

Step 3Toddler Drink / Nutritional SupplementFor toddlers 12 to 36 months of age

INDICATIONS FOR USEGo & Grow by Similac® Step 3 toddler drink is designed to help support growth and development and complement the toddler's diet.1• For oral feeding.Safety precautions:• Not intended for infants under 12 months of age.• Not for tube feeding.• Not for parenteral use.

FEATURES AND BENEFITS• Contains an exclusive blend of DHA, lutein, and vitamin E.• DHA, an Omega-3 fatty acid that supports the normal physical development of the brain and eyes.2• Provides key nutrients such as protein, iron, and calcium.• Contains 0.6 g of galactooligosaccharides (GOS) per serving. • Non-GMO.†• 2 delicious fl avours: Milk and Vanilla.

TECHNICAL DATA

Powder(at standard dilution)

Caloric density (Cal/mL) 0.77Protein (% of total energy) 16Fat (% of total energy) 44Carbohydrate (% of total energy) 40Total Cal:g nitrogen ratio 159:1Non-protein Cal:g nitrogen ratio 134:1

Water (g/L) 900Osmolality (mOsm/kg water) 303Renal solute load (mOsm/L) 279Minimum tube size for gravity/pump feeding (Fr) N/A

Low residue YesGluten-free YesKosher YesHalal Yes

AVAILABILITYPowder0S918301 Go & Grow by Similac® 850-g cans 6/case Step 3, Milk fl avour

0S917301 Go & Grow by Similac® 850-g cans 6/case Step 3, Vanilla

† Ingredients not genetically engineered.

REFERENCES:1. Suthutvoravut U, Abiodun PO, Chomtho S et al. Composition of follow-up formula for young children aged 12-36 months: recommendations of an international expert group coordinated by the Nutrition Association of Thailand and the Early Nutrition Academy. Annals of Nutrition and Metabolism 2015; 67(2):119-32. 2. Canadian Food Inspection Agency: Health Claims – Nutrient Function Claims. Last modified on 2019-10-31. [Accessed online on 2020-07-17].

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GO & GROW BY SIMILAC® Step 3Toddler Drink / Nutritional SupplementFor toddlers 12 to 36 months of age

ENERGYPer 100 g

PowderPer 200 mL

(at standard dilution)ENERGY (Cal [kJ]) 484 (2024) 151 (630)PROTEIN (g) 19 5.9% of total energy 16Nucleotides (mg) 24 7Source Skim milkFAT (g) 23.7 7.4% of total energy 44 Linoleic Acid (g) 4.14 1.3 Arachidonic Acid (ARA) (mg) 9.0 2.8 Linolenic Acid (g) 0.34 0.1 Docosahexaenoic Acid (DHA) (mg) 51.0 16 Omega-6:Omega-3 ratio 8.3:1 Saturates (g) 7.69 2.4Source High oleic sunfl ower oil, soy oil, coconut oil,

DHA and ARAMCT oil (% of total fats) 0CARBOHYDRATE (g) 49.5 15% of total energy 40 Fibre (g) 1.9 0.6 Galactooligosaccharides (GOS) (g) 1.9 0.6Source Skim milk, sucrose, lactose, galactooligosaccharidesAcesulfame-potassium (mg) -Sucralose (mg) -

VITAMINSVitamin A (mcg RAE) 555 173Vitamin D (mcg) 4.0 1.2Vitamin E (mg) 6.6 2.1Vitamin K1 (mg) - -Vitamin C (mg) 72.0 22Thiamine (mg) 1.10 0.3Ribofl avin (mg) 1.15 0.4Niacin (mg) 20.0 6Vitamin B6 (mg) 1.00 0.3Folic Acid (mcg DFE) 170 53Vitamin B12 (mcg) 1.2 0.37Pantothenic Acid (mg) 3.50 1.1Biotin (mcg) 100 31Choline (mg) 110 34Inositol (mg) - -Lutein (mg) 0.512 0.160

MINERALSSodium (mg) 260 81Potassium (mg) 1000 312Chloride (mg) 775 242Calcium (mg) 750 234Phosphorus (mg) 502 157Magnesium (mg) 150 47Iron (mg) 7.0 2.2Zinc (mg) 7.49 2.3Iodide (mg) 0.1 0.031Copper (mg) 1.10 0.3Manganese (mg) 3.00 0.9Selenium (mg) - -Chromium (mg) - -Molybdenum (mg) - -

Nutritional information for Go & Grow by Similac® Step 3, Milk fl avour, 850-g can.

INGREDIENTSGo & Grow by Similac® Step 3, Milk fl avour:

Skim milk, Sugars (sugar, lactose), High oleic sunfl ower oil, Soy oil, Coconut oil, Galactooligosaccharides, Soy lecithin, C. cohnii oil (a source of DHA), M. alpina oil (a source of ARA), Ascorbyl palmitate, Mixed tocopherols, Cytidine 5’-monophosphate, Disodium uridine 5’-monophosphate, Lutein, Adenosine 5’-monophosphate, Disodium guanosine 5’-monophosphate, Minerals (magne-sium chloride, potassium citrate, calcium carbonate, potassium hydroxide, salt, ferrous sulphate, zinc sulphate, manganese sulphate, copper sulphate), Vitamins (ascorbic acid, choline chloride, choline bitartrate, niacinamide, calcium D-pantothenate, vitamin A palmitate, thiamine chloride hydrochloride, pyridoxine hydrochloride, ribofl avin, folic acid, D-biotin, beta-carotene, vitamin D3). As needed: Calcium chloride, Tricalcium phosphate. Contains: Milk, Soy.

Values listed are subject to change. Please refer to the product label or packaging for the most current ingredient, allergen and nutrient profi le information.

INGREDIENTS LISTAS PER COMMODITY # 501-725-002

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GO & GROW BY SIMILAC®

Step 3Toddler Drink / Nutritional SupplementFor toddlers 12 to 36 months of age

INDICATIONS FOR USEGo & Grow by Similac® Step 3 toddler drink is designed to help support growth and development and complement the toddler’s diet.1• For oral feeding.Safety precautions:• Not intended for infants under 12 months of age.• Not for tube feeding.• Not for parenteral use.

FEATURES AND BENEFITS• Provides key nutrients such as protein, iron, calcium, DHA, and

vitamin E.

TECHNICAL DATAReady to use

Caloric density (Cal/mL) 1.0Protein (% of total energy) 16Fat (% of total energy) 30Carbohydrate (% of total energy) 54Total Cal:g nitrogen ratio 160:1Non-protein Cal:g nitrogen ratio 136:1

Water (g/L) 830Osmolality (mOsm/kg water) 600Renal solute load (mOsm/L) 350Minimum tube size for gravity/pump feeding (Fr)

N/A

Low residue YesGluten-free YesKosher YesHalal Yes

AVAILABILITYReady to use66699848 Go & Grow by Similac® 235-mL bottles 4 x 6/case Step 3, Vanilla

REFERENCE:1. Suthutvoravut U, Abiodun PO, Chomtho S et al. Composition of follow-up formula for young children aged 12-36 months: recommendations of an international expert group coordinated by the Nutrition Association of Thailand and the Early Nutrition Academy. Annals of Nutrition and Metabolism 2015;67(2): 119-32.

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GO & GROW BY SIMILAC® Step 3Toddler Drink / Nutritional SupplementFor toddlers 12 to 36 months of age

ENERGYPer 100 mL Per 235 mL

ENERGY (Cal [kJ]) 100 (419) 235 (980)PROTEIN (g) 4.0 9.3% of total energy 16Source Milk protein concentrate, soy protein isolate, whey

protein concentrateFAT (g) 3.3 7.7% of total energy 30 Linoleic Acid (g) 1.3 3.0 Arachidonic Acid (ARA) (g) 0.0014 0.0033 Linolenic Acid (g) 0.19 0.5 Docosahexaenoic Acid (DHA) (g) 0.043 0.01 Omega-6:Omega-3 ratio 6.2:1 Saturates (g) 0.55 1.3Source Soy oil, canola oil, MCT oilMCT oil (% of total fats) 5CARBOHYDRATE (g) 14.0 33% of total energy 54 Fibre (g) 0.4 1.7 Short-chain fructooligosac-

charides (scFOS) (g)0.4 1.0

Galactooligosaccharides (GOS) (g)

- -

Source Sucrose, corn maltodextrin, scFOS, cellulose gelAcesulfame-potassium (mg) - -Sucralose (mg) - -

VITAMINSVitamin A (mcg) 100 235Vitamin D (mcg) 0.3 0.6Vitamin E (mg) 1.0 2.4Vitamin K (mcg) 3 6Vitamin C (mg) 5.1 12Thiamine (mg) 0.14 0.33Ribofl avin (mg) 0.18 0.42Niacin (mg NE) 3.0 7.1Vitamin B6 (mg) 0.18 0.42Folic Acid (mcg DFE) 30 71Vitamin B12 (mcg) 0.1 0.2Pantothenic Acid (mg) 0.6 1.4Biotin (mcg) 12 28Choline (mg) 28 66Inositol (mg) - -Lutein (mg) - -

MINERALSSodium (mg) 38 90Potassium (mg) 191 450Chloride (mg) 87 204Calcium (mg) 106 250Phosphorus (mg) 106 250Magnesium (mg) 23 55Iron (mg) 1.0 2.4Zinc (mg) 1.4 3.3Iodide (mcg) 15 36Copper (mg) 0.15 0.36Manganese (mg) 0.5 1.1Selenium (mcg) 4 10Chromium (mcg) 4 10Molybdenum (mcg) 8 19

INGREDIENTSGo & Grow by Similac® Step 3, Vanilla:

Water, Sugars (sugar), Corn maltodextrin, Milk protein concentrate, Soy oil, Soy protein, Whey protein concentrate, Short-chain fructooligosaccharides (scFOS), Canola oil, Natural and artifi cial fl avours, Cellulose gel, Modifi ed coconut and/or palm kernel oils (medium chain triglycerides), Cellulose gum, Carrageenan, Monoglycerides, Soy lecithin, C. cohnii oil (a source of DHA), M. alpina oil (a source of ARA), Minerals (potassium citrate, magnesium phosphate, tricalcium phosphate, potassium chloride, potassium phosphate, salt, potassium hydrox-ide, zinc sulphate, ferrous sulphate, manganese sulphate, copper sulphate, potassium iodide, sodium molybdate, chromium chloride, sodium selenate), Vitamins (choline chloride, ascorbic acid, niacinamide, DL-alpha-tocopheryl acetate, calcium D-pantothenate, vitamin A palmitate, pyridoxine hydrochloride, thiamine chloride hydrochloride, ribofl avin, folic acid, D-biotin, vitamin D3, cyanocobalamin). Contains: Milk, Soy.

Values listed are subject to change. Please refer to the product label or packaging for the most current ingredient, allergen and nutrient profi le information.

INGREDIENTS LISTAS PER COMMODITY #C6249-02

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PEDIASURE COMPLETE®

GROW & GAIN™Nutritional supplementFor children 1 to 13 years of age

INDICATIONS FOR USEComplete, balanced nutrition to help support growth and develop-ment. PediaSure Complete® Grow & Gain™ can be used with or between meals as part of a healthy diet.• For children: - who lack variety in their diet; - with feeding diffi culties; - who require additional calories and/or nutrients due to a poor appetite or intake; - with high energy and nutrient needs; - with growth faltering.• For oral feeding.Safety precautions:• Not for tube feeding.• Not for parenteral use.• For children under 1 year of age, consult a physician or

qualifi ed health care professional prior to using PediaSure Complete® Grow & Gain™.

FEATURES AND BENEFITS• Provides 26 vitamins and minerals.• 9.3 g protein to help build strong muscles and antibodies.• DHA, an Omega-3 fatty acid that supports the normal physical development of the brain and eyes.1• 1 g of short-chain fructooligosaccharides (scFOS).• 5% of fat as medium-chain triglycerides, an easily digested and well-absorbed fat source.2• Convenient, reclosable bottle.• 2 delicious, kid-approved flavours.

TECHNICAL DATAReady to use

Caloric density (Cal/mL) 1.0Protein (% of total energy) 16Fat (% of total energy) 30Carbohydrate (% of total energy) 54Total Cal:g nitrogen ratio 160:1Non-protein Cal:g nitrogen ratio 136:1

Water (g/L) 830Osmolality (mOsm/kg water) 600Renal solute load (mOsm/L) 350Minimum tube size for gravity/pump feeding (Fr)

N/A

Low residue YesGluten-free YesKosher YesHalal Yes

AVAILABILITYReady to use62491526 PediaSure Complete® 235-mL bottles 4 x 4/case Grow & Gain™, Vanilla62490526 PediaSure Complete® 235-mL bottles 4 x 4/case Grow & Gain™, Chocolate

REFERENCES:1. Canadian Food Inspection Agency: Health Claims – Nutrient Function Claims. Last modifi ed on 2019-10-31. [Accessed online on 2020-07-17]. 2. Duggan C, Watkins JB, Walker WA. Nutrition in Pediatrics: Standard and Specialized Enteral Formulas. BC Decker Inc. Hamilton. 2008.

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GROW & GAINTM

Nutritional SupplementFor children 1 to 13 years of age

ENERGYPer 100 mL Per 235 mL

ENERGY (Cal [kJ]) 100 (419) 235 (984)PROTEIN (g) 4.0 9.3% of total energy 16Source Milk protein concentrate, soy protein isolate, whey

protein concentrateFAT (g) 3.3 7.7% of total energy 30 Linoleic Acid (g) 1.3 3.0 Arachidonic Acid (ARA) (mg) 1.4 3.3 Linolenic Acid (g) 0.19 0.45 Docosahexaenoic Acid (DHA) (mg) 4.25 10.0 Omega-6:Omega-3 ratio 6.2:1Source Soy oil, canola oil, MCT oilMCT oil (% of total fats) 5CARBOHYDRATE (g) 14.0 33.0% of total energy 54 Fibre (g) 0.43 1.0 Short-chain fructooligosac-

charides (scFOS) (g)0.43 1.0

Galactooligosaccharides (GOS) (g) - -Source Sucrose, corn maltodextrin, scFOS, cellulose gel Acesulfame-potassium (mg) - -Sucralose (mg) - -

VITAMINSVitamin A (mcg) 100 235Vitamin D (mg) 0.0003 0.0006Vitamin E (mg) 1 2.4 Vitamin K (mg) 0.003 0.006Vitamin C (mg) 5.1 12.0Thiamine (mg) 0.14 0.33Ribofl avin (mg) 0.18 0.42Niacin (mg) 3.0 7.1Vitamin B6 (mg) 0.18 0.42Folic acid (mg) 0.030 0.071Vitamin B12 (mg) 0.0001 0.0002Pantothenic acid (mg) 0.6 1.4Biotin (mg) 0.012 0.028Choline (mg) 28 66Inositol (mg) - -

MINERALSSodium (mg) 38 90Potassium (mg) 191 450Chloride (mg) 87 204Calcium (mg) 106 250Phosphorus (mg) 106 250Magnesium (mg) 23 55Iron (mg) 1.0 2.4Zinc (mg) 1.4 3.3Iodine (mg) 0.015 0.036Copper (mg) 0.15 0.36Manganese (mg) 0.5 1.1Selenium (mg) 0.004 0.010Chromium (mg) 0.004 0.010Molybdenum (mg) 0.008 0.019

Nutritional information for PediaSure Complete® Grow & Gain™, Vanilla, 235-mL bottle.

INGREDIENTSPediaSure Complete® Grow & Gain™, Vanilla:Water, Sucrose, Corn maltodextrin, Milk protein concentrate, Soy oil, Soy protein isolate, Whey protein concentrate, Short-chain fructooligosaccharides (scFOS), Canola oil, Natural and artifi cial fl avour, Cellulose gel, Medium chain triglycerides, Cellulose gum, Carrageenan, Soy lecithin, Monoglycerides, C. cohnii oil (a source of DHA), M. alpina oil (a source of ARA), MINERALS (potassium citrate, magnesium phosphate, calcium phosphate, potassium chloride, potassium phosphate, sodium chloride, potassium hydroxide, zinc sulphate, ferrous sulphate, manganese sulphate, cupric sulphate, potassium iodide, sodium molybdate, chromium chloride, sodium selenate), VITAMINS (choline chloride, ascorbic acid, niacinamide, DL-alpha-tocopheryl acetate, calcium D-pantothenate, vitamin A palmitate, pyridoxine hydrochloride, thiamine chloride hydrochloride, ribofl avin, folic acid, D-biotin, vitamin D3, cyanocobalamin). Contains: Milk, Soy.

Additional ingredient for Chocolate: Cocoa Powder (Processed with Alkali).

Values listed are subject to change. Please refer to the product label or packaging for the most current ingredient, allergen and nutrient profi le information.

INGREDIENTS LISTAS PER COMMODITY

#C6439-02

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PEDIASURE COMPLETE®

GROW & GAIN™ REDUCED SUGARNutritional supplementFor children 1 to 13 years of age

INDICATIONS FOR USEComplete, balanced nutrition to help support growth and develop-ment. PediaSure Complete® Grow & Gain™ can be used with or between meals as part of a healthy diet.• For children: - who lack variety in their diet; - with feeding diffi culties; - who require additional calories and/or nutrients due to a poor appetite or intake; - with high energy and nutrient needs; - with growth faltering.• For oral feeding.Safety precautions:• Not for tube feeding.• Not for parenteral use.• Maximum of 1 serving per day for children 1 to 3 years old.• Consult a health care professional if child is taking blood thinners.• For children under 1 year of age, consult a physician or

qualifi ed health care professional prior to using PediaSure Complete® Grow & Gain™ Reduced Sugar.

FEATURES AND BENEFITS• 33% less sugar than the original PediaSure Complete® formulation.• Provides 27 vitamins and minerals.• 9 g of protein, to help build strong muscles and antibodies.• DHA, an Omega-3 fatty acid that supports the normal physical development of the brain and eyes.1• 3 delicious, kid-approved fl avours.• Convenient, reclosable bottle.• Low-residue.• Gluten-free.• Kosher.• Halal.

TECHNICAL DATAReady to use

Caloric density (Cal/mL) 1Protein (% of total energy) 15Protein Source Milk protein concentrate, soy proteinFat (% of total energy) 31Omega-6:Omega-3 Ratio 4.7:1MCT oil (% of total fats) 0Fat Source Canola oil, corn oil, soy oil, tuna oilCarbohydrate (% of total energy) 54Carbohydrate Source Corn maltodextrin, sucroseTotal Cal:g Nitrogen Ratio 173:1Nonprotein Cal:g Nitrogen Ratio 148:1Water (g/L) 840Osmolality (mOsm/kg water) 499Renal Solute Load (mOsm/L) 345Recommended Tube Size for Gravity/Pump Feeding (Fr)

N/A

AVAILABILITYReady to use6782164A PediaSure Complete® Grow & Gain™ 235-mL bottles 4 x 4/case Reduced Sugar, Vanilla6782264A PediaSure Complete® Grow & Gain™ 235-mL bottles 4 x 4/case Reduced Sugar, Chocolate6782364A PediaSure Complete® Grow & Gain™ 235-mL bottles 4 x 4/case Reduced Sugar, Strawberry

REFERENCE:1. Canadian Food Inspection Agency: Health Claims – Nutrient Function Claims. Last modified on 2019-10-31. [Accessed online on 2020-07-17].

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Per 100 mL Per 235 mLENERGY, Cal (kJ) 100 (419) 240 (984)PROTEIN, g 3.66 9FAT, g 3.49 8 Polyunsaturates, g 1.28 3 Docosahexaenoic Acid (DHA), mg 14 32 Omega-6, g 1.06 2.5 Omega-3, g 0.21 0.5 Monounsaturates, g 1.49 3.5 Saturates, g 0.43 1 Trans, g 0 0Cholesterol, mg 2.13 5CARBOHYDRATE, g 13.62 32 Fibre, g 0 0 Sugars, g 5.96 14

VITAMINSLutein, mcg 49 120Vitamin A, mcg RE 58 150Vitamin D, mcg 2.55 6Vitamin E, mg 1.0 2.5Vitamin K, mcg 7.2 17Vitamin C, mg 6.4 15Thiamine, mg 0.13 0.30Ribofl avin, mg 0.14 0.30Niacin, mg NE 1.36 3Vitamin B6, mg 0.15 0.35Folate, mcg DFE 26 60Vitamin B12, mcg 0.21 0.5Pantothenic Acid, mg 0.43 1Biotin, mcg 1.9 4.5Choline, mg 23.4 60

MINERALSSodium, mg 38 90Potassium, mg 200 450Chloride, mg 98 225Calcium, mg 140 350Phosphorus, mg 106 250Magnesium, mg 17.9 40Iron, mg 1.15 2.5Zinc, mg 0.70 1.75Iodide, mcg 12.8 30Copper, mg 0.06 0.14Manganese, mg 0.20 0.45Selenium, mcg 3.5 8Chromium, mcg 4.2 10Molybdenum, mcg 4.5 10.5

Nutritional information for PediaSure Complete® Grow & Gain™ Reduced Sugar, Vanilla, 235-mL bottle.

INGREDIENTSPediaSure Complete® Grow & Gain™ Reduced Sugar, Vanilla:Water, Corn maltodextrin, Sugar, Milk protein concentrate, Canola oil, Soy protein, Corn oil, Soy oil, Natural and artifi cial fl avours, Cellulose gel, Tuna oil§, Cellulose gum, Monoglycerides, Soy lecithin, Carrageenan, Stevia leaf extract, Lutein¶, Minerals (potassium citrate, calcium phosphate, potassium chloride, magnesium phosphate, potassium phosphate, calcium carbonate, salt, ferrous sulphate, zinc sulphate, manganese sulphate, copper sulphate, chromium chloride, potassium iodide, sodium molybdate, sodium selenate), Vitamins (ascorbic acid, choline chloride, DL-alpha-tocopheryl acetate, niacinamide, calcium D-pantothenate, thiamine hydrochloride, pyridoxine hydrochloride, ribofl avin, vitamin A palmitate, folic acid, phylloquinone, vitamin D3, biotin, cyanocobalamin). Contains: Milk, Soy. Source per serving of: §0.032 g DHA; ¶0.12 mg Lutein.

PediaSure Complete® Grow & Gain™ Reduced Sugar, Chocolate:Water, Corn maltodextrin, Sugar, Milk protein concentrate, Canola oil, Soy protein, Cocoa powder, Corn oil, Soy oil, Cellulose gel, Tuna oil§, Cellulose gum, Natural and artifi cial fl avours, Monoglycerides, Soy lecithin, Carrageenan, Stevia leaf extract, Lutein¶, Minerals (calcium phosphate, potassium citrate, potassium chloride, potassium phosphate, magnesium phosphate, calcium carbonate, salt, ferrous sulphate, zinc sulphate, manganese sulphate, copper sulphate, chromium chloride, potassium iodide, sodium molybdate, sodium selenate), Vitamins (ascorbic acid, choline chloride, DL-alpha-tocopheryl acetate, niacinamide, calcium D-pantothenate, thiamine hydrochloride, pyridoxine hydrochloride, ribofl avin, vitamin A palmitate, folic acid, phylloquinone, vitamin D3, biotin, cyanocobalamin). Contains: Milk, Soy. Source per serving of: §0.032 g DHA; ¶0.12 mg Lutein.

PediaSure Complete® Grow & Gain™ Reduced Sugar, Strawberry:Water, Corn maltodextrin, Sugar, Milk protein concentrate, Canola oil, Soy protein, Corn oil, Soy oil, Cellulose gel, Natural and artifi cial fl avours, Tuna oil§, Cellulose gum, Monoglycerides, Soy lecithin, Carrageenan, Stevia leaf extract, Erythrosine (colour), Lutein¶, Minerals (potassium citrate, calcium phosphate, potassium chloride, magnesium phosphate, potassium phosphate, calcium carbonate, salt, ferrous sulphate, zinc sulphate, manganese sulphate, copper sulphate, chromium chloride, potassium iodide, sodium molybdate, sodium selenate), Vitamins (ascorbic acid, choline chloride, DL-alpha-tocopheryl acetate, niacinamide, calcium D-pantothenate, thiamine hydrochloride, pyridoxine hydrochloride, ribofl avin, vitamin A palmitate, folic acid, phylloquinone, vitamin D3, biotin, cyanocobalamin). Contains: Milk, Soy. Source per serving of: §0.032 g DHA; ¶0.12 mg Lutein.

Values listed are subject to change. Please refer to the product label or packaging for the most current ingredient, allergen and nutrient profi le information.

PEDIASURE COMPLETE®

GROW & GAINTM REDUCED SUGARNutritional supplementFor children 1 to 13 years of age

INGREDIENTS LISTAS PER COMMODITY

#C6286-01

#C6287-01

#C6288-01

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PEDIASURE®

Sole-source nutritionFor children 1 to 13 years of age

INDICATIONS FOR USE• For children: - requiring short- or long-term tube feeding; - with increased nutrient needs; - with or at risk for malnutrition; - with growth faltering.• For oral or tube feeding use.• Can be used as a supplement or as a sole source of nutrition.Safety precautions:• Not for parenteral use.• For children under 1 year of age, consult a physician or qualifi ed

health care professional prior to using PediaSure®.

FEATURES AND BENEFITS• Fortifi ed with taurine and carnitine to help prevent defi ciencies

associated with long-term tube feeding.1-3

• 19.5% of fat as medium chain triglycerides, an easily digested and well-absorbed fat source.4

• Provides 27 vitamins and minerals.• 3 delicious fl avours to help prevent fl avour fatigue and improve

compliance.

TECHNICAL DATAReady to use

Caloric density (Cal/mL) 1.0Protein (% of total energy) 12.0Fat (% of total energy) 44.2Carbohydrate (% of total energy) 43.8Total Cal:g nitrogen ratio 208:1Non-protein Cal:g nitrogen ratio 183:1

Water (g/L) 854Osmolality (mOsm/kg water) 310 Renal solute load (mOsm/L) 275Minimum tube size for gravity/pump feeding (Fr)

10/8

Low residue YesGluten-free YesKosher YesHalal Yes

AVAILABILITYReady to use62200570 PediaSure®, Vanilla 235-mL cans 12/case62196570 PediaSure®, Chocolate 235-mL cans 12/case62236570 PediaSure®, Strawberry 235-mL cans 12/case

REFERENCES:1. Feller AG et al. Subnormal concentrations of serum selenium and plasma carnitine in chronically tube-fed patients. Am J Clin Nutr 1987;45:476-83. 2. Fischer MH et al. Improved selenium carnitine and tau-rine status in an enterally fed population. JPEN 1990;14:270-4. 3. Bourdet B et al. Plasma Free Carnitine Depletion in Polytrauma Patients. J Nutr Health Aging 2010;14(3):253. 4. Duggan C, Watkins JB, Walker WA. Nutrition in Pediatrics: Standard and Specialized Enteral Formulas. BC Decker Inc. Hamilton. 2008.

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Sole-source nutritionFor children 1 to 13 years of age

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Per 100 mL Per 235 mLENERGY (Cal [kJ]) 100 (419) 235 (984)PROTEIN (g) 3.0 7.1% of total energy 12.0 Taurine (mg) 7.2 17 Carnitine (mg) 1.7 4Source Sodium caseinate, whey protein concentrateFAT (g) 5.0 12% of total energy 44.2 Linoleic acid (g) 0.8 1.9 Linolenic acid (g) 0.1 0.2 Omega-6:Omega-3 ratio 11:1Source High oleic saffl ower oil, soy oil, MCT oilMCT oil (% of total fats) 19.5CARBOHYDRATE (g) 11 26% of total energy 43.8 Fibre (g) - - Short-chain fructooligosac-

charides (scFOS) (g)- -

Galactooligosaccharides (GOS) (g) - -Source Corn maltodextrin, sucroseAcesulfame-potassium (mg) - -Sucralose (mg) - -

VITAMINSVitamin A (IU) 259 608Vitamin D (IU) 32 75Vitamin E (IU) 3.5 8.2Vitamin K (mg) 0.003 0.008Vitamin C (mg) 10 24Thiamine (mg) 0.27 0.64Ribofl avin (mg) 0.21 0.5Niacin (mg) 1.7 4Vitamin B6 (mg) 0.26 0.62Folic acid (mg) 0.037 0.088Vitamin B12 (mg) 0.0006 0.0014Pantothenic acid (mg) 1 2.4Biotin (mg) 0.032 0.076Choline (mg) 30 71Inositol (mg) - -

MINERALSSodium (mg) 37 87Potassium (mg) 130 306Chloride (mg) 101 238Calcium (mg) 97 228Phosphorus (mg) 80 188Magnesium (mg) 20 47Iron (mg) 1.4 3.3Zinc (mg) 1.2 2.8Iodine (mg) 0.0097 0.023Copper (mg) 0.10 0.24Manganese (mg) 0.25 0.59Selenium (mg) 0.0023 0.0054Chromium (mg) 0.0030 0.0071Molybdenum (mg) 0.0036 0.0084

Nutritional information for PediaSure®, Vanilla, 235-mL can.

INGREDIENTSPediaSure®, Vanilla: Water, Corn maltodextrin, Sugar, Sodium caseinate, High oleic saffl ower oil, Soy oil, Modifi ed coconut and/or palm kernel oil (medium chain triglycerides), Whey protein concentrate, Natural and artifi cial fl avour, Soy lecithin, Monoglycerides, Carrageenan, Taurine, L-carnitine, Minerals (calcium phosphate tribasic, potassium citrate, magnesium chloride, potassium phosphate dibasic, potassium chloride, potassium hydroxide, ferrous sulphate, zinc sulphate, manganese sulphate, copper sulphate, potassium iodide, sodium molybdate, sodium selenite), Vitamins (choline chloride, ascorbic acid, DL-alpha tocopheryl acetate, niacinamide, calcium D-pantothenate, thiamine chloride hydrochloride, pyridoxine hydrochloride, ribofl avin, vitamin A palmitate, folic acid, D-biotin, phylloquinone, cyanocobalamin, vitamin D3). As needed: Sodium citrate. Contains: Milk, Soy.

Additional ingredient for Chocolate: Dutched cocoa.Additional ingredient for Strawberry: Colour.

Values listed are subject to change. Please refer to the product label or packaging for the most current ingredient, allergen and nutrient profi le information.

INGREDIENTSLISTAS PER COMMODITY

C6078-01

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PEDIASURE® FIBRESole-source nutritionFor children 1 to 13 years of age

INDICATIONS FOR USE• For children: - who may benefi t from dietary fi bre; - requiring short- or long-term tube feeding; - with increased nutrient needs; - with or at risk for malnutrition; - with growth faltering.• For oral or tube feeding use.• Can be used as a supplement or as a sole source of nutrition.Safety precautions:• Not for parenteral use.• For children under 1 year of age, consult a physician or qualifi ed

health care professional prior to using PediaSure® Fibre.

FEATURES AND BENEFITS• Provides 1.1 g of dietary fi bre per 235 mL.• Fortifi ed with taurine and carnitine to help prevent defi ciencies

associated with long-term tube feeding.1-3

• 19.5% of fat as medium chain triglycerides, an easily digested and well-absorbed fat source.4

• Provides 27 vitamins and minerals.

TECHNICAL DATAReady to use

Caloric density (Cal/mL) 1.0Protein (% of total energy) 12.2Fat (% of total energy) 44.8Carbohydrate (% of total energy) 43.0Total Cal:g nitrogen ratio 206:1Non-protein Cal:g nitrogen ratio 181:1

Water (g/L) 854Osmolality (mOsm/kg water) 345Renal solute load (mOsm/L) 275Minimum tube size for gravity/pump feeding (Fr)

10/8

Low residue NoGluten-free YesKosher YesHalal Yes

AVAILABILITYReady to use62197570 PediaSure® Fibre, Vanilla 235-mL cans 12/case

REFERENCES:1. Feller AG et al. Subnormal concentrations of serum selenium and plasma carnitine in chronically tube-fed patients. Am J Clin Nutr 1987;45:476-83. 2. Fischer MH et al. Improved selenium carnitine and tau-rine status in an enterally fed population. JPEN 1990;14:270-4. 3. Bourdet B et al. Plasma Free Carnitine Depletion in Polytrauma Patients. J Nutr Health Aging 2010;14(3):253. 4. Duggan C, Watkins JB, Walker WA. Nutrition in Pediatrics: Standard and Specialized Enteral Formulas. BC Decker Inc. Hamilton. 2008.

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PEDIASURE® FIBRESole-source nutritionFor children 1 to 13 years of age

ENERGYPer 100 mL Per 235 mL

ENERGY (Cal [kJ]) 100 (419) 235 (984)PROTEIN (g) 3.0 7.1% of total energy 12.2 Taurine (mg) 7.2 17 Carnitine (mg) 1.7 4Source Sodium caseinate, whey protein concentrateFAT (g) 5.0 12% of total energy 44.8 Linoleic acid (g) 0.8 1.9 Linolenic acid (g) 0.1 0.2 Omega-6:Omega-3 ratio 11:1Source High oleic saffl ower oil, soy oil, MCT oilMCT oil (% of total fats) 19.5CARBOHYDRATE (g) 11 26% of total energy 43.0 Fibre (g) 0.5 1.1 Short-chain fructooligosac-

charides (scFOS) (g)- -

Galactooligosaccharides (GOS) (g) - -Source Corn maltodextrin, sucrose, soy polysaccharideAcesulfame-potassium (mg) - -Sucralose (mg) - -

VITAMINSVitamin A (IU) 259 608Vitamin D (IU) 32 75Vitamin E (IU) 3.5 8.2Vitamin K (mg) 0.003 0.008Vitamin C (mg) 10 24Thiamine (mg) 0.27 0.64Ribofl avin (mg) 0.21 0.5Niacin (mg) 1.7 4Vitamin B6 (mg) 0.26 0.62Folic acid (mg) 0.037 0.088Vitamin B12 (mg) 0.0006 0.0014Pantothenic acid (mg) 1 2.4Biotin (mg) 0.032 0.076Choline (mg) 30 71Inositol (mg) - -

MINERALSSodium (mg) 37 87Potassium (mg) 130 306Chloride (mg) 101 238Calcium (mg) 97 228Phosphorus (mg) 80 188Magnesium (mg) 20 47Iron (mg) 1.4 3.3Zinc (mg) 1.2 2.8Iodine (mg) 0.0097 0.023Copper (mg) 0.1 0.24Manganese (mg) 0.25 0.59Selenium (mg) 0.0023 0.0054Chromium (mg) 0.0030 0.0071Molybdenum (mg) 0.0036 0.0084

INGREDIENTSPediaSure® Fibre, Vanilla:Water, Corn maltodextrin, Sugar, Sodium caseinate, High oleic saffl ower oil, Soy oil, Modifi ed coconut and/or palm kernel oil (medium chain triglycerides), Whey protein concentrate, Soy cotyledon fi bre, Natural and artifi cial fl avour, Monoglycerides, Soy lecithin, Carrageenan, Taurine, L-carnitine, Minerals (calcium phosphate tribasic, potassium citrate, magnesium chloride, potassium phosphate dibasic, potassium chloride, potassium hydroxide, ferrous sulphate, zinc sulphate, manganese sulphate, cupric sulphate, potassium iodide, sodium molybdate, sodium selenite), Vitamins (choline chloride, ascorbic acid, DL-alpha tocopheryl acetate, niacinamide, calcium D-pantothenate, thiamine chloride hydrochloride, pyridoxine hydrochloride, ribofl avin, vitamin A palmitate, folic acid, D-biotin, phylloquinone, cyanocobalamin, vitamin D3). As needed: Sodium citrate. Contains: Milk, Soy.

Values listed are subject to change. Please refer to the product label or packaging for the most current ingredient, allergen and nutrient profi le information.

INGREDIENTSLISTAS PER COMMODITY

c6080-01

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PEDIASURE® PLUSSole-source nutritionFor children 1 to 13 years of age

REFERENCES:1. Feller AG et al. Subnormal concentrations of serum selenium and plasma carnitine in chronically tube-fed patients. Am J Clin Nutr 1987;45:476-83. 2. Fischer MH et al. Improved selenium carnitine and tau-rine status in an enterally fed population. JPEN 1990;14:270-4. 3. Bourdet B et al. Plasma Free Carnitine Depletion in Polytrauma Patients. J Nutr Health Aging 2010;14(3):253. 4. Duggan C, Watkins JB, Walker WA. Nutrition in Pediatrics: Standard and Specialized Enteral Formulas. BC Decker Inc. Hamilton. 2008.

INDICATIONS FOR USE• For children: - with fl uid restrictions or volume sensitivity; - who may benefi t from dietary fi bre; - requiring short- or long-term tube feeding; - with increased nutrient needs; - with or at risk for malnutrition; - with growth faltering.• For oral or tube feeding use.• Can be used as a supplement or as a sole source of nutrition.Safety precautions:• Not for parenteral use.• For children under 1 year of age, consult a physician or qualifi ed health care professional prior to using PediaSure® Plus.

FEATURES AND BENEFITS• Increased nutrient density provides more calories in less volume:

118 more calories per serving than PediaSure®.• Provides 2.6 g of dietary fi bre per 235-mL.• Contains 0.82 g of short-chain fructooligosaccharides (scFOS) per

235-mL serving.• Fortifi ed with taurine and carnitine to help prevent defi ciencies

associated with long-term tube feeding.1-3

• 19.6% of fat as medium-chain triglycerides, an easily digested and well-absorbed fat source.4

• Provides 27 vitamins and minerals.

TECHNICAL DATAReady to use

Caloric density (Cal/mL) 1.5Protein (% of total energy) 11.0Fat (% of total energy) 43.3Carbohydrate (% of total energy) 45.7Total Cal:g nitrogen ratio 232:1Non-protein Cal:g nitrogen ratio 207:1

Water (g/L) 778Osmolality (mOsm/kg water) 387Renal solute load (mOsm/L) 348Minimum tube size for gravity/pump feeding (Fr)

10/8

Low residue NoGluten-free YesKosher YesHalal Yes

AVAILABILITYReady to use62244570 PediaSure® Plus, Vanilla 235-mL cans 12/case

IMAGEBANKSEQ#15166

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PEDIASURE® PLUSSole-source nutritionFor children 1 to 13 years of age

ENERGYPer 100 mL Per 235 mL

ENERGY (Cal [kJ]) 150 (628) 353 (1476)PROTEIN (g) 4.2 9.9% of total energy 11.0 Taurine (mg) 11 25 Carnitine (mg) 2.6 6.1Source Sodium and calcium caseinates,

whey protein concentrateFAT (g) 7.5 18% of total energy 43.3 Linoleic acid (g) 1.2 2.8 Linolenic acid (g) 0.1 0.3 Omega-6:Omega-3 ratio 11:1Source High oleic saffl ower oil, soy oil, MCT oilMCT oil (% of total fats) 19.6CARBOHYDRATE (g) 18 42% of total energy 45.7 Fibre (g) 1.1 2.6 Short-chain fructooligosaccharides (scFOS) (g) 0.4 0.8 Galactooligosaccharides (GOS) (g) - -Source Corn maltodextrin, sucrose, scFOS,

uncontaminated modifi ed oat hulls, soy cotyledon fi bre, gum arabic,

carboxymethylcelluloseAcesulfame-potassium (mg) - -Sucralose (mg) - -

VITAMINSVitamin A (IU) 330 776Vitamin D (IU) 45 106Vitamin E (IU) 2.3 5.4Vitamin K (mg) 0.0059 0.014Vitamin C (mg) 10 24Thiamine (mg) 0.27 0.63Ribofl avin (mg) 0.21 0.49Niacin (mg) 1.7 4Vitamin B6 (mg) 0.26 0.61Folic acid (mg) 0.037 0.087Vitamin B12 (mg) 0.0008 0.0019Pantothenic acid (mg) 1 2.4Biotin (mg) 0.032 0.075Choline (mg) 30 71Inositol (mg) 12.0 28

MINERALSSodium (mg) 65 153Potassium (mg) 180 423Chloride (mg) 122 287Calcium (mg) 90 212Phosphorus (mg) 80 188Magnesium (mg) 24 57Iron (mg) 1.4 3.3Zinc (mg) 1.4 3.3Iodine (mg) 0.0097 0.023Copper (mg) 0.17 0.4Manganese (mg) 0.1 0.24Selenium (mg) 0.0023 0.0054Chromium (mg) 0.003 0.0071Molybdenum (mg) 0.0036 0.0085

INGREDIENTSPediaSure® Plus, Vanilla:Water, Corn maltodextrin, High oleic saffl ower oil, Sodium caseinate, Soy oil, Sugar, Modifi ed coconut and/or palm kernel oil (medium chain triglycerides), Calcium caseinate, Whey protein concentrate, Short chain fructooligosaccharides (scFOS), Gluten-free oat fi bre, Soy cotyledon fi bre, Natural and artifi cial fl avour, Gum arabic, Monoglycerides, Soy lecithin, Cellulose gum, Taurine, M-inositol, L-carnitine, Minerals (potassium citrate, calcium phosphate tribasic, magnesium chloride, potassium phosphate dibasic, sodium citrate, sodium chloride, potassium chloride, ferrous sulphate, zinc sulphate, copper sulphate, manganese sulphate, potassium iodide, chromium chloride, sodium molybdate, sodium selenate), Vitamins (choline chloride, ascorbic acid, niacinamide, DL-alpha-tocopheryl acetate, calcium D-pantothenate, thiamine chloride hydrochloride, pyridoxine hydrochloride, ribofl avin, vitamin A palmitate, folic acid, D-biotin, phylloquinone, vitamin D3, cyanocobalamin). As needed: Potassium hydroxide. Contains: Milk, Soy.

Values listed are subject to change. Please refer to the product label or packaging for the most current ingredient, allergen and nutrient profi le information.

INGREDIENTSLISTAS PER COMMODITY

C6082-01

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PEDIASURE® PEPTIDE 1 CALSpecialized peptide-based liquid formulaFor children 1 to 13 years of age

INDICATIONS FOR USEPediaSure® Peptide 1 Cal is a ready-to-drink peptide-based liquid formula for children with impaired gastro-intestinal function. It offers fl exibility to meet nutritional needs both orally or as a tube feeding.• For children with: - GI disease: pancreatitis (acute or chronic) or pancreatic insuf-

fi ciency; cystic fi brosis; Crohn’s disease, ulcerative colitis, or short bowel syndrome; HIV/AIDS-associated enteropathy; celiac disease; gastritis, duodenitis, enterocolitis; dumping syndrome; GI fi stulas;

- GI intolerance symptoms: gas, bloating, diarrhea, andabdominal distention;

- acute GI dysfunction: critical illness; trauma; burns; sepsis; post-transplant surgery; post-gastric surgery;

- impaired GI function: abdominal and other surgeries; certain cancer treatments; generalized malabsorption; generalintolerance to polymeric feedings; cerebral palsy.

• Can be used: - as a supplement or as a sole source of nutrition;

- for early enteral feeding; - as the source of enteral nutrition for dual feeding (parenteral + enteral); - for transition from total parenteral nutrition (TPN) to enteral nutrition.• For oral or tube feeding use.Safety precautions:• Not for parenteral use.• Not for children under the age of 1 unless specifi ed by a health

care professional.

FEATURES AND BENEFITS• Nutrient blend designed to help support tolerance and absorption: - 100% hydrolyzed protein; - 50% of fat as medium-chain triglycerides (MCT), an easily

digested and well-absorbed fat source.1• Contains 1 g of short-chain fructooligosaccharides (scFOS) fi bre per

237-mL serving.• Provides 27 vitamins and minerals.• Convenient, reclosable bottle.

TECHNICAL DATAReady to use

Caloric density (Cal/mL) 1.0Protein (% of total energy) 12.0Fat (% of total energy) 35.0Carbohydrate (% of total energy) 53.0Total Cal:g nitrogen ratio 208:1Non-protein Cal:g nitrogen ratio 183:1

Water (g/L) 844Osmolality (mOsm/kg water) 390Renal solute load (mOsm/L) 265Minimum tube size for gravity/pump feeding (Fr)

10/8

Low residue YesGluten-free YesKosher YesHalal Yes

AVAILABILITYReady to use62119825 PediaSure® Peptide 1 Cal, 237-mL bottles 24/case Vanilla

REFERENCE:1. Duggan C, Watkins JB, Walker WA. Nutrition in Pediatrics: Standard and Specialized Enteral Formulas. BC Decker Inc. Hamilton. 2008.

IMAGEBANKSEQ# 15079

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PEDIASURE® PEPTIDE 1 CALSpecialized peptide-based liquid formulaFor children 1 to 13 years of age

ENERGYPer 100 mL Per 237 mL

ENERGY (Cal [kJ]) 100 (418) 237 (992)PROTEIN (g) 3 7% of total energy 12.0 Taurine (mg) 7.6 18 Carnitine (mg) 1.69 4.0Source Whey protein hydrolysate, hydrolyzed sodium caseinateFAT (g) 4 10% of total energy 35.0 Linoleic acid (g) 0.40 0.95 Linolenic acid (g) 0.15 0.35 Omega 6:Omega 3 ratio 2.7:1Source Structured lipid (interesterifi ed canola oil, MCT oil)MCT oil (% of total fats) 50CARBOHYDRATE (g) 13 32% of total energy 53.0 Fibre (g) 0.3 1 Short-chain

fructooligosaccharides (scFOS) (g)

0.3 1

Galactooligosaccharides (GOS) (g) - -Source Corn maltodextrin, sucrose, scFOSAcesulfame-potassium (mg) - -Sucralose (mg) 6 14

VITAMINSVitamin A (IU) 250 592Vitamin D (IU) 53.0 125Vitamin E (IU) 2.3 5.4Vitamin K (mg) 0.0059 0.014Vitamin C (mg) 10.1 24Thiamine (mg) 0.25 0.6Ribofl avin (mg) 0.21 0.5Niacin (mg) 1.01 2.4Vitamin B6 (mg) 0.25 0.6Folic acid (mg) 0.030 0.071Vitamin B12 (mg) 0.00059 0.0014Pantothenic acid (mg) 1.01 2.4Biotin (mg) 0.019 0.045Choline (mg) 30.0 71Inositol (mg) 8.4 20Lutein (mg) - -

MINERALSSodium (mg) 70 170Potassium (mg) 135 320Chloride (mg) 101 240Calcium (mg) 106 250Phosphorus (mg) 84.4 200Magnesium (mg) 19.8 47Iron (mg) 1.4 3.3Zinc (mg) 1.18 2.8Iodine (mg) 0.00969 0.023Copper (mg) 0.10 0.24Manganese (mg) 0.17 0.4Selenium (mg) 0.0032 0.0076Chromium (mg) 0.0030 0.0071Molybdenum (mg) 0.00359 0.0085

INGREDIENTSPediaSure® Peptide 1 Cal, Vanilla: Water, corn maltodextrin, sucrose, whey protein hydrolysate, structured lipid (interesterifi ed canola oil and medium chain triglycerides*), hydrolyzed sodium caseinate, MINERALS (calcium phosphate, potassium citrate, magnesium phosphate, potassium chloride, magnesium chloride, sodium citrate, ferrous sulphate, zinc sulphate, manganese sulphate, cupric sulphate, chromium chloride, potassium iodide, sodium selenate, sodium molybdate), medium chain triglycerides*, canola oil, short-chain fructooligosaccharides, natural and artifi cial fl avours, VITAMINS (ascorbic acid, choline chloride, m-inositol, dl-alpha-tocopheryl acetate, calcium d-pantothenate, niacinamide, thiamine chloride hydrochloride, pyridoxine hydrochloride, ribofl avin, vitamin A palmitate, folic acid, biotin, phylloquinone, cyanocobalamin, vitamin D3), cellulose gel, soy lecithin, carrageenan, sucralose, cellulose gum, taurine, L-carnitine. Contains: Milk, Soy.

* Modifi ed coconut and/or palm kernel oils.

Values listed are subject to change. Please refer to the product label or packaging for the most current ingredient, allergen and nutrient profi le information.

INGREDIENTS LISTAS PER COMMODITY

C5787-01 SEQ 15079

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Specialty P

rod

ucts

SPECIALTY PRODUCTSIN THIS SECTIONPedialyte® Pedialyte® AdvancedCare® Plus Pedialyte® AdvancedCare® Plus Powder SticksPedialyte® AdvancedCare®

Pedialyte® Powder SticksPedialyte® Freezer PopsPedialyte® (HFS)Similac® 5% Glucose Water (HFS)Similac® Sterilized WaterRCF®

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Spec

ialt

y P

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SPECIALTY PRODUCTS

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PEDIALYTE® DOSAGE CHART

Pedialyte® is scientifi cally formulated for fast, effective rehydration for both children and adults.

Refer to dosage chart for the recommended amount of Pedialyte® required for maintenance of fl uids and electrolytes. Total daily intake should be adjusted to meet individual needs based on ongoing losses, thirst, and response to therapy.

RECOMMENDED DOSE

Infants < 1 year of age Consult a physician before using Pedialyte®.

Children 1 year of age 50 – 100 mL per episode of diarrhea and/or vomiting, up to a maximum of 1 L over a period of 24 hours.

Children 2 to 9 years 100 – 200 mL per episode of diarrhea and/or vomiting, up to a maximum of 1 L over a period of 8 to 24 hours.

Adults, adolescents, and children ≥ 10 years

200 – 400 mL per episode of diarrhea and/or vomiting, or as much as wanted.

• Attempt to give/take Pedialyte® as soon as diarrhea begins.• Give/take frequently in small amounts (e.g. 5 mL) gradually increased, as tolerated. If more solution is requested/desired, give/take more, as tolerated.

For children, including infants < 1 year old, the Canadian Pediatric Society recommends that 50 to 100 mL/kg of oral rehydration solution (ORS) be given over 4 hours, to treat mild to moderate dehydration due to acute gastroenteritis.1 It is also suggested to:• Give small amounts at frequent intervals;• Use a spoon or dropper for very small infants;• Increase the amount of ORS based on ongoing losses,

such as diarrhea and vomiting;• Feed an age-appropriate diet after rehydration;• If breastfeeding, continue during rehydration therapy.1

REFERENCE:1. Leung A, Prince T. Oral rehydration therapy and early refeeding in the management of childhood gastroenteritis. Canadian Paediatric Society Nutrition and Gastroenterology Committee. Paediatr Child Health 2006;11(8):527-31. Reaffi rmed 2016.

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PEDIALYTE®Oral rehydration solution for all ages

INDICATIONS FOR USEPedialyte® is specially formulated to help prevent dehydration in children and adults by restoring nutrients lost during diarrhea and vomiting. Can be used for maintenance of water and electrolytes following corrective parenteral therapy for diarrhea.Safety precautions: • Not for parenteral use.• For infants under 1 year, consult a physician or qualifi ed health care

professional before using Pedialyte® as infants and young children are at greater risk of dehydration.

FEATURES AND BENEFITS• #1 doctor and pharmacist recommended brand.• Provides glucose to promote sodium and water absorption.• Contains the balance of sodium and sugar recommended by experts1,2 to help prevent dehydration due to diarrhea and vomiting.• Helps replenish zinc lost during diarrhea.3,4

• Promotes fl uid absorption more effectively than common house-hold beverages.

• Low osmolality.• 1-L reclosable bottles for easy measuring and pouring.• Unfl avoured liquid available for infants – no artifi cal sweeteners, dyes, or fl avours.• 2 delicious fl avours to encourage compliance.

TECHNICAL DATAReady to useUnfl avoured

Ready to useFlavoured

Caloric density (Cal/mL) 0.10 0.10Protein (% of total energy) 0 0Fat (% of total energy) 0 0Carbohydrate (% of total energy) 100 100Total Cal:g nitrogen ratio N/A N/ANon-protein Cal:g nitrogen ratio N/A N/A

Water (g/L) 978 973-975Osmolality (mOsm/kg water) 250 270Renal solute load (mOsm/L) 100 100Minimum tube size for gravity/pump feeding (Fr)

N/A N/A

Low residue Yes YesGluten-free Yes YesKosher Yes YesHalal Yes Yes (Grape)

No (Fruit)

AVAILABILITYReady to use66467803 Pedialyte®, Unfl avoured 1-L reclosable 8/case plastic bottles

66469803 Pedialyte®, Grape 1-L reclosable 8/case plastic bottles

66468803 Pedialyte®, Fruit 1-L reclosable 8/case plastic bottles

REFERENCES:1. World Health Organization. Oral Rehydration Salts: Production of the new ORS. 2006. 2. Leung A,Prince T. Oral Rehydration therapy and early refeeding in the management of childhood gastroenteritis. Canadian Paediatric Society Nutrition and Gastroenterology Committee. Paediatr Child Health 2006;11(8):527-31. 3. Bhatnagar S et al. Zinc with oral rehydration therapy reduces stool output and dura-tion of diarrhea in hospitalized children: a randomized controlled trial. Journal of Pediatric Gastroentero-logy and Nutrition 2004;38(1):34-40. 4. Lukacik M, Thomas RL, Aranda JV. A meta-analysis of the effects of oral zinc in the treatment of acute and persistent diarrhea. Pediatrics 2008;121(2):326-36.

IMAGEBANKPedialyte®,

seq# 15060, 14989, 14976

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Per 100 mL Per 1000 mLENERGY (Cal [kJ]) 10 (42) 100 (418)

MEDICINAL INGREDIENTSDextrose (g) 2.5 25Sodium (mg [mmol]) 104 (4.5) 1035 (45)Potassium (mg [mmol]) 78.2 (2.0) 782 (20)Chloride (mg [mmol]) 124 (3.5) 1240 (35)Zinc (mg) 0.78 7.8Citrate (unfl avoured) (g [mmol]) 0.26 (1.4) 2.64 (14.0)Citrate (fl avoured) (g [mmol]) 0.48 (2.6) 4.8 (25.5)Nutritional information for Pedialyte®, Unfl avoured.

INGREDIENTSPedialyte®, Unfl avoured:MEDICINAL INGREDIENTS: Dextrose, potassium citrate, sodium chloride, sodium citrate, citric acid, zinc gluconate.NON-MEDICINAL INGREDIENT: Water.

Pedialyte®, Grape:MEDICINAL INGREDIENTS: Dextrose, citric acid, potassium citrate, sodium chloride, sodium citrate, zinc gluconate.NON-MEDICINAL INGREDIENTS: Water, artifi cial fl avour, sucralose, acesulfame-potassium,FD&C Red Nº 40, FD&C Blue Nº 1.

Pedialyte®, Fruit:MEDICINAL INGREDIENTS: Dextrose, citric acid, potassium citrate, sodium chloride, sodium citrate, zinc gluconate.NON-MEDICINAL INGREDIENTS: Water, natural and artifi cial fl avours, sucralose,acesulfame-potassium, FD&C Yellow Nº 6.

Values listed are subject to change. Please refer to the product label or packaging for the most current ingredient, allergen and nutrient profi le information.

INGREDIENTS LISTAS PER COMMODITY

Pedialyte® Unfl avoured: C5869-02

Pedialyte® Grape: C5833-05

Pedialyte® Fruit: C5986-07

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IMAGEBANKPedialyte® AdvancedCare® Plus,

Berry Frost: C5046-01_14878

Cherry Pomegranate: C5048_14880

PEDIALYTE®

ADVANCEDCARE® PLUSOral rehydration solution for all ages

INDICATIONS FOR USEPedialyte® AdvancedCare® Plus is formulated with 33% more elec-trolytes* to replenish electrolytes lost during diarrhea and vomiting to help prevent dehydration. Can be used for maintenance of water and electrolytes following corrective parenteral therapy for diarrhea.Safety precautions:• Not for parenteral use.• Not for children with milk allergy, GOS allergy or galactosemia.• For infants under 1 year, consult a physician or qualifi ed health care

professional before using Pedialyte® AdvancedCare® Plus as infants and young children are at greater risk of dehydration.

FEATURES AND BENEFITS• #1 doctor and pharmacist recommended brand.• 33% more electrolytes* for higher electrolyte loss. • Contains PreActiv® prebiotics in the form of

galactooligosaccharides (GOS) that help stimulate the growth of good bacteria in the large intestine.

• Provides glucose to promote sodium and water absorption.• Contains the balance of sodium and sugar recommended

by experts1,2 to help prevent dehydration due to diarrhea and vomiting.

• Helps replenish zinc lost during diarrhea.3,4

• Promotes fl uid absorption more effectively than common household beverages.

• 1-L reclosable bottles for easy measuring and pouring.• 2 delicious fl avours to encourage compliance.• Low osmolality.• Gluten-free.• Kosher.• Halal. TECHNICAL DATA

Ready to useCaloric Density (Cal/mL) 0.07Protein (% of total energy) 0Protein Source N/AFat (% of total energy) 0MCT oil (% of total fats) N/AOmega-6:Omega-3 Ratio N/AFat Source N/ACarbohydrate (% of total energy) 100Carbohydrate Source N/ATotal Cal:g Nitrogen Ratio N/ANonprotein Cal:g Nitrogen Ratio N/A

Water (g/L) 970Osmolality (mOsm/kg water) 265Renal Solute Load (mOsm/L) 130Minimum Tube Size for Gravity/Pump Feeding (Fr)

N/A

AVAILABILITYReady to use67293803 Pedialyte® AdvancedCare® Plus, 1-L reclosable 8/case Berry Frost plastic bottles

67294803 Pedialyte® AdvancedCare® Plus, 1-L reclosable 8/case Cherry Pomegranate plastic bottles

* Sodium electrolytes per equal volume compared to other Pedialyte® products.REFERENCES:1. World Health Organization. Oral Rehydration Salts: Production of the new ORS. 2006. 2 Leung A, Prince T. Paediatr Child Health 2006;11(8):527-31. 3. Bhatnagar S et al. JPGN 2004;38(1):34-40. 4. Lukacik M et al. Pediatrics 2008;121(2):326-36.

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IMAGEBANKPedialyte® AdvancedCare® Plus,

Berry Frost: C5046-01_14878

Cherry Pomegranate: C5048_14880

PEDIALYTE®

ADVANCEDCARE® PLUSOral rehydration solution for all ages

NU

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Per 100 mL Per 1000 mLENERGY (Cal [kJ]) 7.0 (29) 70 (293)

MEDICINAL INGREDIENTSDextrose, g 1.6 16Galactooligosaccharides (GOS), g 0.32 3.2Sodium, mg (mmol) 138 (6.0) 1380 (60)Potassium, mg (mmol) 78.0 (2.0) 780 (20)Chloride, mg (mmol) 177 (5.0) 1770 (50)Zinc, mg 0.78 7.8Citrate, g (mmol) 0.47 (2.48) 4.7 (24.8)

INGREDIENTSPedialyte® AdvancedCare® Plus, Berry Frost:MEDICINAL INGREDIENTS: Dextrose, galactooligosaccharides (GOS), sodium chloride, citric acid, potassium citrate, sodium citrate, zinc gluconate.NON-MEDICINAL INGREDIENTS: Water, natural and artifi cial fl avours, sucralose, acesulfame-potassium, FD&C Blue No 1.

Pedialyte® AdvancedCare® Plus, Cherry Pomegranate:MEDICINAL INGREDIENTS: Dextrose, galactooligosaccharides (GOS), citric acid, potassium citrate, sodium chloride, sodium citrate, zinc gluconate. NON-MEDICINAL INGREDIENTS: Water, natural and artifi cial fl avours, sucralose, acesulfame-potassium, FD&C Blue No 1, FD&C Red No 40.

Values listed are subject to change. Please refer to the product label or packaging for the most current ingredient, allergen and nutrient profi le information.

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IMAGEBANKPedialyte® AdvancedCare Plus®

Powder Sticks,

C5046-01_14883,

C5058_14886

PEDIALYTE® ADVANCEDCARE® PLUSPowder SticksOral rehydration solution for all ages

INDICATIONS FOR USEPedialyte® AdvancedCare® Plus is formulated with 33% more elec-trolytes* to replenish electrolytes lost during diarrhea and vomiting to help prevent dehydration. Can be used for maintenance of water and electrolytes following corrective parenteral therapy for diarrhea.Safety precautions:• Not for parenteral use.• For infants under 1 year, consult a physician or qualifed health care

professional before using Pedialyte® AdvancedCare® Plus as infants and young children are at greater risk of dehydration.

FEATURES AND BENEFITS• #1 doctor and pharmacist recommended brand.• 33% more electrolytes* for higher electrolyte loss.• Contains PreActiv® prebiotics in the form of short-chain fructooli-

gosaccharides (scFOS) that help stimulate the growth of good bacteria in the large intestine.

• When mixed with 500 mL of water: - contains the balance of sodium and sugar recommended by

experts1,2 to help prevent dehydration due to diarrhea and vomiting;

- promotes fl uid absorption more effectively than common household beverages.

• 2 delicious fl avours to encourage compliance.• Low osmolality.• Gluten-free.• Kosher.• Halal. TECHNICAL DATA

Powder(at standard dilution)

Caloric Density (Cal/mL) 0.1Protein (% of total energy) 0Protein Source N/AFat (% of total energy) 0MCT oil (% of total fats) N/AOmega-6:Omega-3 Ratio N/AFat Source N/ACarbohydrate (% of total energy) 100Carbohydrate Source N/ATotal Cal:g Nitrogen Ratio N/ANonprotein Cal:g Nitrogen Ratio N/A

Water (g/L) 960Osmolality (mOsm/kg water) 265Renal Solute Load (mOsm/L) 130Minimum Tube Size for Gravity/Pump Feeding (Fr)

N/A

AVAILABILITYPowder66969673 Pedialyte® AdvancedCare® Plus 6 x 17-g sticks 6/case Powder Sticks, Berry Frost66972673 Pedialyte® AdvancedCare® Plus 6 x 17-g sticks 6/case Powder Sticks, Strawberry Freeze

* Sodium electrolytes per equal volume compared to other Pedialyte® products.REFERENCES:1. World Health Organization. Oral Rehydration Salts: Production of the new ORS. 2006. 2. Leung A, Prince T. Paediatr Child Health 2006;11(8):527-31.

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INGREDIENTS LISTAS PER COMMODITY

Pedialyte® AdvancedCare Plus®

Powder Sticks,

C5046-01_14883,

C5058_14886

PEDIALYTE® ADVANCEDCARE® PLUSPowder SticksOral rehydration solution for all ages

NU

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NA

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Per 100 mL(at standard dilution)

Per 17-g stick (at standard dilution)

ENERGY (Cal [kJ]) 9.8 (41) 50 (209)

MEDICINAL INGREDIENTSDextrose, g 2.11 10.8Short-chain fructooligosaccharides (scFOS), g

0.14 0.71

Sodium, mg (mmol) 127 (5.5) 650 (30)Potassium, mg (mmol) 72 (1.8) 370 (10)Chloride, mg (mmol) 164 (4.6) 840 (25)Citrate, g (mmol) 0.5 (2.53) 2.57 (13)

Nutritional information for Pedialyte® AdvancedCare® Plus, Berry Frost, powder stick.

INGREDIENTSPedialyte® AdvancedCare® Plus, Berry Frost, Powder Sticks:MEDICINAL INGREDIENTS: Dextrose, short-chain fructooligosaccharides, citric acid, sodium chloride, potassium citrate, sodium citrate.NON-MEDICINAL INGREDIENTS: Natural and artifi cial fl avours, calcium silicate, acesulfame-potassium, sucralose, FD&C Blue Nº 1.

Pedialyte® AdvancedCare® Plus, Strawberry Freeze, Powder Sticks :MEDICINAL INGREDIENTS: Dextrose, short-chain fructooligosaccharides, citric acid, sodium chloride, potassium citrate, sodium citrate.NON-MEDICINAL INGREDIENTS: Natural fl avour, calcium silicate, acesulfame-potassium, sucralose, FD&C Red Nº 40, FD&C Blue Nº 1.

Values listed are subject to change. Please refer to the product label or packaging for the most current ingredient, allergen and nutrient profi le information.

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IMAGEBANKPedialyte® AdvancedCareTM, Cherry Punch:

C5831-01 seq# 15044

Pedialyte® AdvancedCareTM, Blue Raspberry:

C5824-01 seq# 14980

PEDIALYTE®

ADVANCEDCARE®Oral rehydration solution for all ages

INDICATIONS FOR USEPedialyte® AdvancedCare® contains PreActiv® prebiotics and is specially formulated to help prevent dehydration in children and adults by restoring nutrients lost during diarrhea and vomiting. Can be used for maintenance of water and electrolytes following corrective parenteral therapy for diarrhea.Safety precautions:• Not for parenteral use.• Not for children with milk allergy, GOS allergy, or galactosemia.• For infants under 1 year, consult a physician or qualifi ed health care

professional before using Pedialyte® AdvancedCare® as infants and young children are at greater risk of dehydration.

FEATURES AND BENEFITS• #1 doctor and pharmacist recommended brand. • Contains PreActiv® prebiotics in the form of galactooligosac- charides (GOS) that help stimulate the growth of good bacteria in the large intestine.• Provides glucose to promote sodium and water absorption.• Contains the balance of sodium and sugar recommended by experts1,2 to help prevent dehydration due to diarrhea and vomiting.• Helps replenish zinc lost during diarrhea.3,4

• Promotes fl uid absorption more effectively than common household beverages.• Low osmolality.• 1-L reclosable bottles for easy measuring and pouring.• 2 delicious fl avours to encourage compliance.

TECHNICAL DATAReady to use

Caloric density (Cal/mL) 0.07Protein (% of total energy) 0Fat (% of total energy) 0Carbohydrate (% of total energy) 100Total Cal:g nitrogen ratio N/ANon-protein Cal:g nitrogen ratio N/A

Water (g/L) 970Osmolality (mOsm/kg water) 226 (Cherry Punch)

239 (Blue Raspberry)Renal solute load (mOsm/L) 100Minimum tube size for gravity/pump feeding (Fr)

N/A

Low residue YesGluten-free YesKosher YesHalal No (Cherry Punch)

Yes (Blue Raspberry)

AVAILABILITYReady to use66470803 Pedialyte® AdvancedCare®, Cherry Punch 1-L reclosable 8/case plastic bottles

66471803 Pedialyte® AdvancedCare®, Blue Raspberry 1-L reclosable 8/case plastic bottles

REFERENCES:1. World Health Organization. Oral Rehydration Salts: Production of the new ORS. 2006. 2. Leung A, Prince T. Oral Rehydration therapy and early refeeding in the management of childhood gastroenteritis. Canadian Paediatric Society Nutrition and Gastroenterology Committee. Paediatr Child Health 2006;11(8):527-31. 3. Bhatnagar S et al. Zinc with oral rehydration therapy reduces stool output and duration of diarrhea in hospitalized children: a randomized controlled trial. Journal of Pediatric Gastro-enterology and Nutrition 2004;38(1):34-40. 4. Lukacik M, Thomas RL, Aranda JV. A meta-analysis of the effects of oral zinc in the treatment of acute and persistent diarrhea. Pediatrics 2008;121(2):326-36.

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IMAGEBANKPedialyte® AdvancedCareTM, Cherry Punch:

C5831-01 seq# 15044

Pedialyte® AdvancedCareTM, Blue Raspberry:

C5824-01 seq# 14980

PEDIALYTE® ADVANCEDCARE®Oral rehydration solution for all ages

NU

TRITIO

NA

L INFO

RM

ATIO

NENERGY

Per 100 mL Per 1000 mLENERGY (Cal [kJ]) 7 (29.3) 70 (293)

MEDICINAL INGREDIENTSDextrose (g) 1.6 16Galactooligosaccharides (GOS) (g) 0.32 3.2Sodium (mg [mmol]) 103 (4.5) 1030 (45)Potassium (mg [mmol]) 78.2 (2.0) 782 (20)Chloride (mg [mmol]) 124 (3.5) 1244 (35)Zinc (mg) 0.78 7.8Citrate (g [mmol]) 0.48 (2.55) 4.8 (25.5)

INGREDIENTSPedialyte® AdvancedCare®, Cherry Punch:MEDICINAL INGREDIENTS: Dextrose, galactooligosaccharides, citric acid, potassium citrate, sodium chloride, sodium citrate, zinc gluconate. NON-MEDICINAL INGREDIENTS: Water, natural and artifi cial fl avours, sucralose, acesulfame-potassium, FD&C Red Nº 40.

Pedialyte® AdvancedCare®, Blue Raspberry:MEDICINAL INGREDIENTS: Dextrose, galactooligosaccharides, citric acid, potassium citrate, sodium chloride, sodium citrate, zinc gluconate. NON-MEDICINAL INGREDIENTS: Water, natural and artifi cial fl avours, sucralose, acesulfame-potassium, FD&C Blue Nº 1, FD&C Red Nº 40.

Values listed are subject to change. Please refer to the product label or packaging for the most current ingredient, allergen and nutrient profi le information.

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IMAGEBANKPedialyte® POWDER PACKS,

seq# 15033,15040

PEDIALYTE®

Powder SticksOral rehydration solution for all ages

INDICATIONS FOR USEPedialyte® is specially formulated to help prevent dehydration in children and adults by restoring nutrients lost during diarrhea and vomiting. Can be used for maintenance of water and electrolytes following corrective parenteral therapy for diarrhea.Safety precautions:• Not for parenteral use.• For infants under 1 year, consult a physician or qualifi ed health care

professional before using Pedialyte® as infants and young children are at greater risk of dehydration.

FEATURES AND BENEFITS• #1 doctor and pharmacist recommended brand.• When mixed with 250 mL of water: - Contains the balance of sodium and sugar recommended by experts1,2 to help prevent dehydration due to diarrhea and vomiting; - Promotes fl uid absorption more effectively than common household beverages.• Low osmolality.• Convenient powder format.• 2 delicious fl avours to encourage compliance.

TECHNICAL DATAPowder

(at standard dilution)Caloric density (Cal/mL) 0.10Protein (% of total energy) 0Fat (% of total energy) 0Carbohydrate (% of total energy) 100Total Cal:g nitrogen ratio N/ANon-protein Cal:g nitrogen ratio N/A

Water (g/L) 970Osmolality (mOsm/kg water) 265Renal solute load (mOsm/L) 80Minimum tube size for gravity/pump feeding (Fr)

N/A

Low residue YesGluten-free YesKosher YesHalal Yes

AVAILABILITYPowder66474793 Pedialyte® Powder Sticks, Apple 8 x 8.5-g sticks 8/case

66473793 Pedialyte® Powder Sticks, Fruit Punch 8 x 8.5-g sticks 8/case

REFERENCES:1. World Health Organization. Oral Rehydration Salts: Production of the new ORS. 2006. 2. Leung A, Prince T. Oral Rehydration therapy and early refeeding in the management of childhood gastroenteritis.Canadian Paediatric Society Nutrition and Gastroenterology Committee. Paediatr Child Health 2006;11(8):527-31.

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INGREDIENTS LISTAS PER COMMODITY

Pedialyte® Apple, powder: C5841-01 SEQ 15040

Pedialyte® Fruit Punch, powder: C5838-01 SEQ 15033

PEDIALYTE® Powder SticksOral rehydration solution for all ages

NU

TRITIO

NA

L INFO

RM

ATIO

NENERGY

Per 250 mL(at standard dilution)

ENERGY (Cal [kJ]) 23 (96)

MEDICINAL INGREDIENTSDextrose (g) 5.7Sodium (mg [mmol]) 244 (10.6)Potassium (mg [mmol]) 184 (4.7)Chloride (mg [mmol]) 294 (8.3)Citrate (g [mmol]) 1.15 (6.1)

INGREDIENTSPedialyte® Powder Sticks, Apple:MEDICINAL INGREDIENTS: Dextrose, citric acid, potassium citrate, sodium chloride, sodium citrate.NON-MEDICINAL INGREDIENTS: Malic acid, artifi cial apple fl avour, caramel colour, sucralose, acesulfame-potassium.

Pedialyte® Powder Sticks, Fruit Punch:MEDICINAL INGREDIENTS: Dextrose, citric acid, potassium citrate, sodium chloride, sodium citrate.NON-MEDICINAL INGREDIENTS: Malic acid, natural and artifi cial fruit punch fl avours, sucralose, acesulfame-potassium, FD&C Red Nº 40.

Values listed are subject to change. Please refer to the product label or packaging for the most current ingredient, allergen and nutrient profi le information.

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IMAGEBANKPedialyte® POPS,

seq# 15086

PEDIALYTE®

Freezer PopsOral rehydration solution for all ages

INDICATIONS FOR USEPedialyte® is specially formulated to help prevent dehydration in children and adults by restoring nutrients lost during diarrhea and vomiting. Can be used for maintenance of water and electrolytes following corrective parenteral therapy for diarrhea. Safety precautions:• Not for parenteral use.• For infants under 1 year, consult a physician or qualifi ed health care

professional before using Pedialyte® as infants and young children are at greater risk of dehydration.

FEATURES AND BENEFITS• #1 doctor and pharmacist recommended brand.• Provides glucose to promote sodium and water absorption.• Contains the balance of sodium and sugar recommended by

experts1,2 to help prevent dehydration due to diarrhea and vomiting.

• Promotes fl uid absorption more effectively than common household beverages.

• Low osmolality.• 4 delicious fl avours to enhance compliance.

TECHNICAL DATAReady to use

Caloric density (Cal/mL) 0.10Protein (% of total energy) 0Fat (% of total energy) 0Carbohydrate (% of total energy) 100Total Cal:g nitrogen ratio N/ANon-protein Cal:g nitrogen ratio N/A

Water (g/L) 973Osmolality (mOsm/kg water) 270Renal solute load (mOsm/L) 100Minimum tube size for gravity/pump feeding (Fr)

N/A

Low residue YesGluten-free YesKosher YesHalal Yes

AVAILABILITYReady to use00245189 Pedialyte® Freezer Pops, 16 x 62.5-mL 8 x 16/case Variety Pack† sleeves

† Grape, Cherry, Orange, and Blue Raspberry. REFERENCES:1. World Health Organization. Oral Rehydration Salts Production of the new ORS. 2006. 2. Leung A, Prince T. Oral Rehydration therapy and early refeeding in the management of childhood gastroenteritis. Canadian Paediatric Society Nutrition and Gastroenterology Committee. Paediatr Child Health 2006;11(8):527-31.

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INGREDIENTS LISTAS PER COMMODITY

Pedialyte® POPS: C5835-04

SEQ 15086

PEDIALYTE® Freezer PopsOral rehydration solution for all ages

NU

TRITIO

NA

L INFO

RM

ATIO

NENERGY

Per 62.5-mLFreezer Pop

ENERGY (Cal [kJ]) 6.3 (26.1)

MEDICINAL INGREDIENTSDextrose (g) 1.6Sodium (g [mmol]) 0.65 (2.8)Potassium (g [mmol]) 0.488 (1.3)Chloride (g [mmol]) 7.78 (2.2)

INGREDIENTSPedialyte® Freezer Pops, Grape, Cherry, Orange, and Blue Raspberry:MEDICINAL INGREDIENTS: Sodium chloride, potassium citrate.NON-MEDICINAL INGREDIENTS: Water, dextrose (25 g / L), citric acid, sodium carboxymethyl cellulose, potassium sorbate, sodium benzoate, sucralose, acesulfame-potassium.

Grape also contains: Natural and artifi cial grape fl avours, FD&C Red Nº 40, FD&C Blue Nº 1.

Cherry also contains: Natural and artifi cial cherry fl avours, FD&C Red Nº 40.

Orange also contains: Natural and artifi cial orange fl avours, FD&C Yellow Nº 6, FD&C Red Nº 40.

Blue Raspberry also contains: Natural and artifi cial blue raspberry fl avours, FD&C Blue Nº 1.

Values listed are subject to change. Please refer to the product label or packaging for the most current ingredient, allergen and nutrient profi le information.

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PEDIALYTE®

Oral rehydration solution

INDICATIONS FOR USEPedialyte® is specially formulated to help prevent dehydration in infants and children by restoring nutrients lost during diarrhea and vomiting. Can be used for maintenance of water and electrolytes following corrective parenteral therapy for diarrhea. • For oral or tube feeding use.Safety precautions:• Not for parenteral use.• For use under medical supervision. Infants and young children are at greater risk of dehydration.

FEATURES AND BENEFITS• Designed to prevent dehydration more effectively than common

household beverages.• Provides glucose to promote sodium and water absorption.• Restores electrolytes lost during diarrhea and vomiting to help prevent dehydration.• Helps replenish zinc lost during diarrhea.1,2

• Low osmolality.• Unfl avoured for infants.• Ready to use – no mixing or dilution necessary.

TECHNICAL DATAReady to use Unfl avoured

Caloric density (Cal/mL) 0.10Protein (% of total energy) 0Fat (% of total energy) 0Carbohydrate (% of total energy) 100Total Cal:g nitrogen ratio N/ANon-protein Cal:g nitrogen ratio N/A

Water (g/L) 978Osmolality (mOsm/kg water) 250Renal solute load (mOsm/L) 100Minimum tube size for gravity/pump feeding (Fr)

N/A

Low residue YesGluten-free YesKosher YesHalal Yes

AVAILABILITYReady to use59892871 Pedialyte® Unfl avoured 59-mL plastic 48/case bottles

REFERENCES:1. Bhatnagar S et al. Zinc with oral rehydration therapy reduces stool output and duration of diarrhea in hospitalized children: a randomized controlled trial. Journal of Pediatric Gastroenterology and Nutrition 2004;38(1):34-40. 2. Lukacik M, Thomas RL, Aranda JV. A meta-analysis of the effects of oral zinc in the treatment of acute and persistent diarrhea. Pediatrics 2008;121(2):326-36.

IMAGEBANKSEQ#15452

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PEDIALYTE®

Oral rehydration solution

NU

TRITIO

NA

L INFO

RM

ATIO

NENERGY

Per 100 mL Per 59 mLENERGY (Cal [kJ]) 10 (42) 6 (25)

MEDICINAL INGREDIENTSDextrose (g) 2.5 1.5Sodium (mg [mmol]) 104 (4.5) 61 (2.7)Potassium (mg [mmol]) 78.2 (2.0) 46.1 (1.2)Chloride (mg [mmol]) 124 (3.5) 73 (2.1)Zinc (mg) 0.78 0.5Citrate (mg [mmol]) 0.26 (1.4) 0.15 (0.8)

INGREDIENTSPedialyte®, Unfl avoured:MEDICINAL INGREDIENTS: Dextrose, potassium citrate, sodium chloride, sodium citrate, citric acid, zinc gluconate.NON-MEDICINAL INGREDIENTS: Water.

Values listed are subject to change. Please refer to the product label or packaging for the most current ingredient, allergen and nutrient profi le information.

INGREDIENTSLISTAS PER COMMODITY

C7105-03

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SIMILAC®

5% GLUCOSE WATER

INDICATIONS FOR USE• For oral use.• Use under medical supervision.

FEATURES AND BENEFITS• Ready to use.

TECHNICAL DATAReady to use

Caloric density (Cal/mL) 0.2Protein (% of total energy) 0Fat (% of total energy) 0Carbohydrate (% of total energy) 100Total Cal:g nitrogen ratio N/ANon-protein Cal:g nitrogen ratio N/A

Water (%) 96.6Osmolality (mOsm/kg water) N/ARenal solute load (mOsm/L) N/AMinimum tube size for gravity/pump feeding (Fr)

N/A

Low residue YesGluten-free YesKosher YesHalal Yes

AVAILABILITYReady to use51002871 Similac® 5% Glucose Water 59-mL plastic 48/case bottles

ENERGYPer 100 mL Per 100 Cal Per 1000 mL Per 59 mL

ENERGY (Cal [kJ]) 20 (85) 100 (418) 200 (837) 12 (50)CARBOHYDRATE (g) 5 25 50 3% of total energy 100Source Dextrose

INGREDIENTSSimilac® 5% Glucose Water, Ready to use:Water, Sugars (dextrose).

Values listed are subject to change. Please refer to the product label or packaging for the most current ingredient, allergen and nutrient profi le information.

IMAGEBANKSEQ#14977

INGREDIENTS LISTAS PER COMMODITY #C5718-01 14979

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SIMILAC®

STERILIZED WATER

INDICATIONS FOR USE• For use as drinking water or for other oral or enteral purposes.• Use under medical supervision.Safety Precaution:• Not for parenteral use.

FEATURES AND BENEFITS• Ready to use.

TECHNICAL DATAReady to use

Caloric density (Cal/mL) N/AProtein (% of total energy) N/AFat (% of total energy) N/ACarbohydrate (% of total energy) N/ATotal Cal:g nitrogen ratio N/ANon-protein Cal:g nitrogen ratio N/A

Water (%) 100Osmolality (mOsm/kg water) N/ARenal solute load (mOsm/L) N/AMinimum tube size for gravity/pump feeding (Fr)

N/A

Low residue YesGluten-free YesKosher YesHalal Yes

AVAILABILITYReady to use51000871 Similac® Sterilized Water 59-mL plastic 48/case bottles

58037803 Similac® Sterilized Water 1-L reclosable plastic 8/case bottles

Values listed are subject to change. Please refer to the product label or packaging for the most current ingredient, allergen and nutrient profi le information.

IMAGEBANKSEQ#14966 (1 L)

SEQ#15055

INGREDIENTS LISTAS PER COMMODITY C5724-01

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RCF®No added carbohydrate soy-based iron-fortifi ed infant formula

INDICATIONS FOR USE• For use in the dietary management of infants: - Who are unable to tolerate the type or amount of carbohydrate in milk or conventional infant formulas; - With seizure disorders requiring a ketogenic diet.• Use under medical supervision.Safety precaution:• Not for parenteral use.

FEATURES AND BENEFITS• The only commercial formula available for the dietary management of seizures in infants.• Formulated to allow the health care professional to prescribe the

type and amount of carbohydrate (that can be tolerated) with the assurance that other nutrient needs will be met.

• Soy protein isolate to avoid symptoms of cow’s milk-protein allergy or sensitivity.

• 1.8 mg of iron (as ferrous sulfate) per 100 Cal if carbohydrate is added to make a 20 Cal/30 mL (68 Cal/100 mL) feeding.• L-carnitine (3 mg/100 mL) and taurine (12 mg/100 mL).• Lactose-free.

TECHNICAL DATAConcentrated

liquidCaloric density (Cal/mL) 0.81Protein (% of total energy) 20Fat (% of total energy) 80Carbohydrate (% of total energy) 0Total Cal:g nitrogen ratio 127:1Non-protein Cal:g nitrogen ratio 101:1

Water (g/L) 880Osmolality (mOsm/kg water) 90Renal solute load (mOsm/L) 34.8Minimum tube size for gravity/pump feeding (Fr)

N/A

Low residue YesGluten-free YesKosher YesHalal Yes

AVAILABILITYConcentrated liquid00108B12 RCF® 384-mL cans 12/case

PREPARATIONFor 20 Cal/30 mL formula:Use the type and amount of carbohydrate specifi ed by a health care professional (see table below). 1. Dissolve carbohydrate in 355 mL of water, cover, and bring to a

boil. Keep covered; allow to cool. 2. Rinse can lid and shake very well. Open with clean punch-type

opener. 3. Add RCF® to cooled carbohydrate solution prepared in step 1.

Mix and pour into bottles (or cup).Once feeding begins, use within 1 hour or discard.

For 54 g of carbohydrate, add one of the following:Table sugar (Sucrose) 60 mL (4 level Tbsp)Fructose powder 60 mL (4 level Tbsp)Dextrose powder (Hydrous) 90 mL (6 level Tbsp)

IMAGEBANKSEQ#15261

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RCF®No added carbohydrate soy-based iron-fortifi edinfant formula

NU

TRITIO

NA

L INFO

RM

ATIO

NENERGY

Per 100 mL(concentrated liquid)

Per 100 Cal(standard dilution)†

ENERGY (Cal [kJ]) 81 (339) 100 (418)PROTEIN (g) 4.0 3.0Source Soy protein isolate, L-methionineFAT (g) 7.2 5.3 Linoleic Acid (g) 1.352 1.000 Arachidonic Acid (ARA) (g) - - Linolenic Acid (g) - - Docosahexaenoic Acid (DHA) (g) - - Omega-6:Omega-3 ratio 10.6:1Source High oleic saffl ower oil, soy oil, coconut oilMCT oil (% of total fats) 0.0CARBOHYDRATE (g) 0.07 10.1 Total dietary fi bre (g) - - Short-chain fructooligosac- charides (scFOS) (g)

- -

Galactooligosaccharides (GOS) (g) - -Source N/AAcesulfame-potassium (mg) - -Sucralose (mg) - -

VITAMINSVitamin A (RE [IU]) 122 (405) 90 (300)Vitamin D3 (mcg [IU]) 2.0 (81) 1.5 (60)Vitamin E (IU) 2.0 1.5Vitamin K (mg) 0.015 0.011Vitamin C (mg) 12 9Thiamine (mg) 0.08 0.06Ribofl avin (mg) 0.12 0.09Niacin (mg) 1.80 1.35Vitamin B6 (mg) 0.08 0.06Folic acid (mg) 0.020 0.015Vitamin B12 (mg) 0.0006 0.0004Pantothenic acid (mg) 1.00 0.75Biotin (mg) 0.0061 0.0045Choline (mg) 15.7 12Inositol (mg) 6.5 5Lutein (mg) - -

MINERALSSodium (mg) 59.1 44Potassium (mg) 146 108Chloride (mg) 83 62Calcium (mg) 140 105Phosphorus (mg) 100 75Magnesium (mg) 10.0 7.5Iron (mg) 2.4 1.8Zinc (mg) 1.0 0.75Iodine (mg) 0.0203 0.015Copper (mg) 0.100 0.075Manganese (mg) 0.034 0.025Selenium (mg) 0.0027 0.0018Chromium (mg) - -Molybdenum (mg) - -

† 54 g of carbohydrate + 355 mL of water, mixed with 384 mL of RCF®; yields ~770 mL.

INGREDIENTSRCF®, Concentrated liquid:Water, Soy protein, High oleic saffl ower oil, Soy oil, Coconut oil, Mono- and diglycerides, Soy lecithin, Carrageenan, L-methionine, Taurine, M-inositol, L-carnitine, Minerals (tricalcium phosphate, potassium citrate, potassium chloride, magnesium chloride, sodium chloride, ferrous sulphate, zinc sulphate, copper sulphate, potassium iodide, sodium selenate), Vitamins (ascorbic acid, choline chloride, niacinamide, D-alpha-tocopheryl acetate, calcium D-pantothenate, thiamine chloride hydrochloride, vitamin A palmitate, ribofl avin, pyridoxine hydrochloride, folic acid, phylloquinone, D-biotin, beta-carotene, vitamin D3, cyanocobalamin). As needed: Calcium carbonate, Potassium hydroxide. Contains: Soy.

Values listed are subject to change. Please refer to the product label or packaging for the most current ingredient, allergen and nutrient profi le information.

INGREDIENTS LISTAS PER COMMODITY #OL-039-2

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NOTES:

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Accesso

ries

ACCESSORIESIN THIS SECTIONComponent Nipple SystemPlastic Bottle and CapCustomFeed® BottleVolu-Feed® Dispensing Cap

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Acc

esso

ries

ACCESSORIES

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Similac® component nipple system allows for fl exibility to choose a nipple that matches each infant’s sucking strength or need.Compatible with all Abbott bottles, including:• 59-mL Hospital Feeding System bottles.• 240-mL plastic bottle.• CustomFeed® bottle.

Similac® InfantNipple and Ring#00079125 (250/case)

Description Product Composition Latex-freeDesigned for use with term infants or for infants with developed sucking strength.

Nipple: polyisopreneRing: polyethylene Yes

Similac® OrthodonticNipple and Ring#50512125 (250/case)

Description Product Composition Latex-freeDesigned for newborn infants (term or preterm). Opening faces infant’s palate and orthodontic design stimulates oral exercise while feeding.

Nipple: natural rubber latex

Ring: polyethyleneNo

Similac® PrematureNipple and Ring#00094125 (250/case)

Description Product Composition Latex-freeDesigned for preterm infants with less developed sucking strength. Decreased bulb wall thickness increases pliability and makes it easier to suckle.

Nipple: polyisopreneRing: polyethylene Yes

Similac® Slow FlowNipple and Ring#53894125 (250/case)

Description Product Composition Latex-freeDesigned to support the underdeveloped “suck-swallow-breathe” coordination of low-birth-weight or preterm infants. Provides a more infant-driven, controlled fl ow rate vs. faster-fl ow nipples for increased physiological stability and a more effi cient sucking pattern.1

Nipple: polyisopreneRing: polyethylene Yes

FEATURES AND BENEFITS• Easy to use.• Nipples and rings are individually pre-packaged and ready for use.• Nipples and rings form a seal to prevent leakage during feeding.

WARNINGS• DO NOT use as a pacifi er, as it presents a choking hazard.• Keep out of reach of children.

REFERENCE:1. Chang YJ et al. Effects of Single-Hole and Cross-Cut Nipple Units on Feeding Effi ciency and Physiological Parameters in Premature Infants. J Nurs Res 2007;150(3):215-23.

COMPONENT NIPPLE SYSTEM

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PLASTIC BOTTLE AND CAP

Plastic Bottle#00875114 (144/case)Description Product Composition Latex-freeVolume: 240 mL.Designed for use as a nursing bottle. Polypropylene Yes

COMPATIBLE WITH• All Similac® nipples.• Plastic bottle cap.

FEATURES AND BENEFITS• Ready to use.• Food-grade quality.• Unbreakable; safe for pediatric nurseries.• Dishwasher-safe (top rack only).• Disposable.

Plastic Bottle Cap#54080125 (250/case)Description Product Composition Latex-freeStandard 40 mm fi nish. Polypropylene Yes

COMPATIBLE WITH• 59-mL Hospital Feeding System bottles.• 240-mL plastic bottle.• CustomFeed® bottle.

FEATURES AND BENEFITS• Food-grade quality.• Dishwasher-safe (top rack only).• Can be prepared for use by placing in boiling water for 1 minute or

washed in the top rack of a dishwasher.

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CUSTOMFEED® BOTTLEBreastmilk Storage Bottle with Cap

CustomFeed® Bottle#66962099 (100/case)Description Product Composition Latex-free

Designed for storage and accurate measurement of breast milk or formula. Volume: 60 mL.

Polypropylene Yes

COMPATIBLE WITH• Breast pumps that fi t standard-size bottles.• All Similac® nipples.• Plastic bottle cap.• Volu-Feed® dispensing cap.

FEATURES AND BENEFITS• 60-mL sterile bottle and cap (combined in a sealed package).• Easy-to-read, graduated measures (1 mL calibrations). • Freezable; store between 0°C and -40°C. Do not fi ll beyond 60 mL.• Disposable or reusable.†• Dishwasher safe (top rack only).• Manufactured without BPA, latex, and DEHP.

Volu-Feed® Dispensing Cap#00081125 (250/case)Description Product Composition Latex-freePermits tube feeding using CustomFeed® bottle by holding feeding tube in place.

Polypropylene Yes

FEATURES AND BENEFITS• Single use.• Ready to use - individually packaged in a sealed, clean-peel

blisterpack.• Disposable.

COMPATIBLE WITH• CustomFeed® bottle.

Sterile

† For reuse, follow Health Canada guidelines for sterilization.

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NOTES:

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Ad

ditio

nal Inform

ation

ADDITIONAL INFORMATIONIN THIS SECTIONAlberta Reimbursement ListOntario Reimbursement ListQuebec Reimbursement ListSaskatchewan Reimbursement List

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Ad

dit

iona

l Inf

orm

atio

n

ADDITIONAL INFORMATION

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ALBERTAREIMBURSEMENTLIST

For more information, visit: http://www.health.alberta.ca/services/drug-benefi t-list.html.

The following Abbott nutritional products are listed on the Alberta Human Services Drug Benefi t Supplement.

PIN Description Format

REGULAR (UNRESTRICTED) BENEFITS999901 Ensure® Regular, All fl avours 235-mL bottles999902 Ensure® Plus Calories, All fl avours 235-mL bottles999902 Ensure® Plus, All fl avours 235-mL cans999940 Glucerna® nutritional drink, All fl avours 237-mL bottles989998 PediaSure® Peptide 1 Cal, Vanilla 237-mL bottles999938 Jevity® 1 Cal, Unfl avoured 235-mL cans999545 Nepro®, Vanilla 237-mL bottles999545 Nepro®, Vanilla 1000-mL RTH containers80074173 Pedialyte®, All fl avours 1-L bottles80072902 Pedialyte®, Unfl avoured 1-L bottles999933 PediaSure®, All fl avours 235-mL cans990029 PediaSure® Fibre, Vanilla 235-mL cans999449 Similac® Alimentum®, Unfl avoured 237-mL cans999788 Similac® Alimentum®, Unfl avoured 400-g cans999465 Similac® Neosure®, Unfl avoured 363-g cans999414 Suplena®, Vanilla 235-mL cans

SPECIAL AUTHORIZATION999404 Ensure® pudding, All fl avours 113-g cups999416 Jevity® 1.2 Cal, Unfl avoured 235-mL cans999416 Jevity® 1.2 Cal, Unfl avoured 1500-mL RTH containers999475 Jevity® 1.5 Cal, Unfl avoured 235-mL cans999475 Jevity® 1.5 Cal, Unfl avoured 1500-mL RTH containers999434 PediaSure® Plus, Vanilla 235-mL cans999430 TwoCal® HN, Vanilla 235-mL cans999430 TwoCal® HN, Vanilla 1000-mL RTH containers

RTH = Ready-to-hang.

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ONTARIOREIMBURSEMENTLIST

RTH = Ready-to-hang.

PIN Description Format

ADULT AND PEDIATRIC80074173 Pedialyte®, All fl avours 1-L bottles80072902 Pedialyte®, Unfl avoured 1-L bottles

ADULT97904333 Ensure® Plus, All fl avours 235-mL cans9854392 Glucerna® 1.0 Cal, Vanilla 235-mL cans97984060 Jevity® 1 Cal, Unfl avoured 235-mL cans9854096 Jevity® 1.2 Cal, Unfl avoured 235-mL cans9857117 Jevity® 1.2 Cal, Unfl avoured 1500-mL RTH containers9857344 Jevity® 1.5 Cal, Unfl avoured 235-mL cans9857312 Jevity® 1.5 Cal, Unfl avoured 1500-mL RTH containers9854169 Osmolite® 1.2 Cal, Unfl avoured 235-mL cans9857095 Osmolite® 1.2 Cal, Unfl avoured 1500-mL RTH containers9853731 Suplena®, Vanilla 235-mL cans9858101 Vital® Peptide 1.0 Cal, Vanilla 220-mL bottles9858102 Vital® Peptide 1.5 Cal, Vanilla 220-mL bottles9858103 Vital® Peptide 1.5 Cal, Vanilla 1000-mL RTH containers9854380 TwoCal® HN, Vanilla 235-mL cans

PEDIATRIC 97984370 PediaSure®, All fl avours 235-mL cans9854371 PediaSure® Fibre, Vanilla 235-mL cans9857419 PediaSure® Plus, Vanilla 235-mL cans9857523 PediaSure® Peptide 1 Cal, Vanilla 237-mL bottles97984558 Similac® Alimentum®, Unfl avoured 237-mL cans9857564 Similac® Alimentum®, Unfl avoured 400-g cans9857124 Similac® Neosure®, Unfl avoured 363-g cans

For more information, visit: http://www.health.gov.on.ca/en/public/programs/drugs/programs/odb/opdp_nutrition.aspx.

The following Abbott nutritional products are listed on the Ontario Drug Benefi t (ODB) Formulary.

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QUEBECREIMBURSEMENTLIST

The following Abbott nutritional products are listed on the Régie de l'assurance maladie du Québec (RAMQ) List of Medications.

RTH = Ready-to-hang.

RAMQ Code

ExceptionDrugStatus Code

Description Format

ADULT POLYMERIC FORMULAS00920347 Glucerna® 1.0 Cal, Vanilla 235-mL cans99000482 Jevity® 1 Cal, Unfl avoured 235-mL cans99003392 Jevity® 1.2 Cal, Unfl avoured 235-mL cans99003600 Jevity® 1.2 Cal, Unfl avoured 1500-mL RTH containers99100417 Jevity® 1.5 Cal, Unfl avoured 235-mL cans99100402 Jevity® 1.5 Cal, Unfl avoured 1500-mL RTH containers99100702 Nepro®, Vanilla 237-mL bottles99100703 Nepro®, Vanilla 1000-mL RTH containers99004224 Osmolite® 1.2 Cal, Unfl avoured 235-mL cans99004216 Osmolite® 1.2 Cal, Unfl avoured 1500-mL RTH containers99001543 Promote®, Vanilla 235-mL cans99002647 Suplena®, Vanilla 235-mL cans99004690 TwoCal® HN, Vanilla 235-mL cans99100462 TwoCal® HN, Vanilla 1000-mL RTH containers

PEDIATRIC POLYMERIC FORMULAS99000474 PediaSure®, All fl avours 235-mL cans99001381 PediaSure® Fibre, Vanilla 235-mL cans99005050 PediaSure® Plus, Vanilla 235-mL cans

SEMI-ELEMENTAL 99101182 VA98 Vital® Peptide 1 Cal, Vanilla 220-mL bottles99101183 VA98 Vital® Peptide 1.5 Cal, Vanilla 220-mL bottles99101178 VA98 Vital® Peptide 1.5 Cal, Vanilla 1000-mL RTH

containers99101181 VA98 PediaSure® Peptide 1 Cal, Vanilla 237-mL bottles

CASEIN HYDROLYSATE-BASED (INFANTS AND CHILDREN)

99100206 VA105 Similac® Alimentum®, Unfl avoured 237-mL cans

POST-DISCHARGE FORMULAS FOR PRETERM INFANTS99100123 VA104 Similac® Neosure®, Unfl avoured 363-g cans

For more information, visit: https://www.ramq.gouv.qc.ca/fr/professionnels/professionnels/Pages/liste-medicaments.aspx

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SASKATCHEWANREIMBURSEMENTLIST

SASKATCHEWANREIMBURSEMENTLIST

RTH = Ready-to-hang.

Description Format

THERAPEUTIC NUTRITIONAL PRODUCTS PROGRAMGlucerna® 1.0 Cal, Vanilla 235-mL cansJevity® 1.0 Cal, Unfl avoured 235-mL cansJevity® 1.2 Cal, Unfl avoured 235-mL cansJevity® 1.2 Cal, Unfl avoured 1500-mL RTH containersJevity® 1.5 Cal, Unfl avoured 235-mL cansJevity® 1.5 Cal, Unfl avoured 1500-mL RTH containersNepro®, Vanilla 237-mL bottlesNepro®, Vanilla 1000-mL RTH containersOsmolite® 1.2 Cal, Unfl avoured 235-mL cansOsmolite® 1.2 Cal, Unfl avoured 1000-mL RTH containersPediaSure Complete® Grow & GainTM, All fl avours 235-mL bottlesPediaSure®, All fl avours 235-mL cansPediaSure® Fibre, Vanilla 235-mL cansPediaSure® Plus, Vanilla 235-mL cansPediaSure® Peptide 1 Cal, Vanilla 237-mL bottlesPromote®, Vanilla 235-mL cansRCF®, Unfl avoured 384-mL cansSimilac® Alimentum®, Unfl avoured 237-mL cansSimilac® Alimentum®, Unfl avoured 400-g cansSimilac® Neosure®, Unfl avoured 363-g cansSuplena®, Vanilla 235-mL cansTwoCal® HN, Vanilla 235-mL cansTwoCal® HN, Vanilla 1000-mL RTH containersVital® Peptide 1 Cal, Vanilla 220-mL bottlesVital® Peptide 1.5 Cal, Vanilla 220-mL bottlesVital® Peptide 1.5 Cal, Vanilla 1000-mL RTH containers

MODULAR SUPPLEMENT – eligible if combined with eligible formula

LiquiProtein® 54-mL bottles

CYSTIC FIBROSIS PROGRAMEnsure® Regular, All fl avours 235-mL bottlesEnsure® pudding, All fl avours 113-g cupsGlucerna® 1.0 Cal, Vanilla 235-mL cansPediaSure®, All fl avours 235-mL cansPediaSure® Fibre, Vanilla 235-mL cansPediaSure® Plus, Vanilla 235-mL cansPediaSure Complete® Grow & GainTM, All fl avours 235-mL bottlesPediaSure® Peptide 1 Cal, Vanilla 237-mL bottlesVital® Peptide 1 Cal, Vanilla 220-mL bottlesVital® Peptide 1.5 Cal, Vanilla 220-mL bottlesVital® Peptide 1.5 Cal, Vanilla 1000-mL RTH containers

For more information, visit: https://www.saskatchewan.ca/residents/health/accessing-health-care-services/health-services-for-people-with-disabilities/sail.

The following Abbott nutritional products are listed by the Saskatchewan Aids to Independent Living(SAIL) Program.

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