.7.rr. AJoA..

~AL~$N /2/ f6rio,

9 AVL3-

Photography makes this engineer's notesan indisputable record 6~It's the photograph of the oscillograph traces that preserves a record of performance longin this engineer's notebook that makes the after the circuit has been torn down, and re-

page an indisputable record of wave form tains it for detailed study whenever you wish.* variations in passing from second harmonic Eastman Kodak Company, Industrial Photo-

distortion, through a nearly pure sine wave, graphic Division, Rochester 4, N. Y.to third harmonic distortion.With photography, your oscillograph is P O O EO DN

much more than a testing and measuring de- P O O E O DNvice. It becomes, in addition, an instrument ... an important function of photography

The subject in itsearth scienceaspects

I

I

Gives equalemphasis to facts

I~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

and prnci,plesotzoology

IIOver SOO usefulorganic compounds

Treats fundamentalconcepts in detail

Latest in awell-known seriesI

II

JOHN WILEY & SON

PHYSICAL GEOGRAPHYBy ARTHUR N. STRAHLER, Columbia University. Presents physical

geography as a basic earth science in its own right. In this book, Dr. Strahleris primarily concerned with explaining the processes and forms which havebeen developed in the atmosphere and hydrosphere and on the earth's landsurface. Although the author uses many regional examples and outlines theglobal distribution pattejns of weather and climates, he does not attempt anencyclopedic region-by-region description of the world-he puts his firstemphasis on principles rather than descriptive details. Physical Geographycontains authoritative, readable material on time, tides, illumination, weather,the great soil groups, rocks, folds and faults, and other physical attributes.The extremely broad coverage is reflected in a set of full-color Visual Aids,which will soon be available to supplement the text. May 1931. Approx. 442double-column pages. 514 illus. Prob. $6.50

MAN AND THE ANIMAL WORLDBy BERNAL R. WEiMER, Bethany College. Since the animal that the stu-

dent knows most about is man, Man and the Animal World begins with a studyof man as an introduction to the life principles and processes manifested inother animals. The book is carefully balanced-giving equal stress to the factsand basic principles of zoology while maintaining interest and presenting allthe important, basic information. Dr. Weimer presents a brief natural historysurvey of the various taxonomic groups and gives adequate emphasis to thephysiology of animals and their importance from the standpoint of humanhealth, food supply, and other aspects of zoology. Combining rigor withhuman appeal, the author has designed this book for a one-semester course inzoology which will give the student the full perspective of structure, physi-ology and animal relations. 321 illustrations serve as an excellent teaching aid.May 1951. Approx. 518 pages. $S.00.

PREPARATION OF ORGANIC INTERMEDIATESBy DAVID A. SEuLEY, Tulane University. April 1951. Approx. 308 pages.Prob. $6.00.

OPTICAL CRYSTALLOGRAPHYSecond edition by ERNEST E. WAHLSTROM, University of Colorado. April1951. 247 pages. $4.50.

ORGANIC REACTIONS, Volume VIEditor-in-Chief, ROGER ADAMS, University of Illinois. May 1951. Approx.519 pages. In press.

Send for copies on approval.

S, INC. 440 Fourth Avenue New York 16, N. Y.

April 13, 1951 11

INTERSCIENCEMEDICINAL CHEMISTRY-Chemistry, Biochemistry, Therapeutic, and Pharmaco-

logical Action of Natural and Synthetic Drugs.In two volumes.

By ALFRED BURGER, Associate Professor of Chemistry, University of Virginia.

VOLUME I-May 1951. 6 x 9. 595 pages, 58 tables. $10.00VOLUME II-September 1951. 6 x 9. approx. 490 pages, 60 tables. $10.00

This book is written as an advanced treatise ona professional level. Emphasis has been placedon chemical aspects. The author reviews struc-tural analysis and syntheses of important me-dicinal chemicals, biological testing, and thera-peutic usefulness as well as medicinal and veter-inary drawbacks. While mainly designed for thechemist, biochemist, and pharmacologist in re-search and industry, it will acquaint the physi-cian with the background and newer develop-ments of drugs and give him an appreciation ofthe scientific work that has made his therapeutictools possible.

Contents-VOLUME I-1. Introduction. 2. Historical De-velopment of Medicinal Chemistry. 3. Relationof Chemical Structure and Biological Activity.4. Physical Properties and Biological Activity(Isostrism). 5. Biological Study of Drugs. 6.Restricted Response of Cells to Drugs. 7. Gen-eral Anesthetics. 8. Local Anesthetics. 9. Hyp-notics and Sedatives. 10. Anticonvulsant Drugs.

11. Analgetics. 12. Analeptics. 13. Cardiovas-cular Drugs. 14. Parenteral Fluid Therapy. 15.Diuretics. 16. Anticoagulants. 17. Drugs ElicitingSymptoms in the Gastro-intestinal Tract. -18.Sedative, Anodyne, and Stimulant Expectorants.19. Adrenergic Drugs. 20. Adrenergic BlockingAgents. 21. Parasympathetic Stimulants. 22.Curare and Curariform Drugs. 23. Antispas-modics. 24. Histamine and Antihistaminic Drugs.25. Diagnostic Agents. 26. Thyroxine and Anti-thyroid Drugs. 27. Drugs for the Treatment ofCancer. 28. The Vitamins.

VOLUME 11-29. The Hormones. 30. EssentialAmino Acids and Fatty Acids. 31. Chemother-apy. 32. Theories of Metabolite Antagenism. 33.Dyestuffs in Chemotherapy. 34. The Sulfona-mide Drugsi. 35. Antimalarials. 36. Chemotherapyof Acid-fast Infections. 37. Metal-free DrugsUsed in Tropical Diseases. 38. Antibiotics.39. Antifungal Agents. 40. Anthelmintics. 41.Chemotherapeutic Compounds of Arsenic, Anti-mony, and Bismuth. 42. Sterilization and Dis-infection. 43. Antiseptics.

METHODS OF VITAMIN ASSAYPrepared and edited by The Association of Vitamin Chemists, Inc.Second edition completely revised and augmented.1951. x 9. 322 pages, 10 illus. $5.50

Over 50% new material!Larger by 114 pages!

A completely new book!

The wide acceptance of the first edition encouraged the prepa-ration of this second edition, in which methods have been re-

vised to incorporate pertinent information from the currentliterature as well as modifications in procedure suggested by themany users of the book.

SOYBEANS AND SOYBEAN PRODUCTS-Their Chemistry and Technology.In two volumes. Edited by KLARE S. MARKLEY. tVOLUME I. 1950. 6 x 9. 558 pages. 123 illus., 92 tables., 1 col. plate. $11.00 L7"tVOLUME II: 1951. 6 x 9. 624 pages, 92 illus., 81 tables., 1 col. plate. $11.00 pultidhedl

THEORY OF ELECTRONSBy L. ROSENFELD, Professor of Theoretical Physics, University of Manchester.1951. 6 x 9. 135 pages, 7 illus. $2.25

AL books available on approval.Write for our latest complete catalog.

INTERSCIENCE PUBLISHERS, INC., 250 Fifth Avenue, New York 1, N. Y.

69LL

pulfI& ed

April 13, 1951 13

PERSONNEL PLACEMENTYOUR ad here reaches over 32,000 foremost scientistsin the leading educational institutions, industriallaboratories, and research foundations in the U. S.and 76 foreign countries -at a very low cost

CLASSIFIED: 15# per word, minimum charge $3.00. Useof Box Number counts as 10 additional words.

DISPLAY: $17.50 per inch, no charge for Box Number.Correct payment to SCIENCE must accompany all ads.Insertion usually made 2 or 3 weeks after receipt of ad.SCIENCE * 1515 Mass. Ave., N.W., Wash. 5, D. C.

||||1|||||||||||||||||POSITIONS WANTED 1||||||||||||||||||

Bacteriologist-B.S., single, draft exempt. Two years PublicHealth; special studies food bacteriology, chemical background.Box 483, SCIENCE. X

Bacteriologist: M.Sc., Ph.D. June. Professional and teaching ex-perience. Extensive training bacterial metabolism, virology, medi-cal bacteriology. Skilled in Warburg techniques, spectroscopy,chromatography. Current research: purine-pyrimidine metabolism.Box 487, SCIENCE. X

Entomologist: M.S. Field and chemical experience, desires indus-trial or teaching position. Box 484, SCIENCE. 4/20

Parasitologist, Ph.D. Publications in parasitic physiology, tax-onomy, epidemiology. Available June. Box 455, SCIENCE. 6/13

Positions Wanted:(a) Bacteriologist; Ph.D.; eight years' teaching experience (Bac-teriology); four years, research bacteriologist and three years,director, development bacteriology, pharmaceutical industry. (b)Physical Chemist; Ph.D., sixteen years on faculty, medical col-lege and director clinical laboratories; perfers teaching or director-ship research in clinical chemistry. For further information, pleasewrite Science Division, Medical Bureau (Burneice Larson, Di-rector) Palmolive Building, Chicago. X

Student, B.S. (Physics), M.A. (Applied Mathematics), desiressummer position. Box 488, SCIENCE. X

Zoologist (Ph.D. Parasitology). Desires teaching position withopportunity for research. Five years' college teaching experience.Available Sept. '51. Box 466, SCIENCE. R 4/13-20

Zoologist: Ph.D. Teaching position. General. Invertebrate. Publi-cations. Midwest preferred. Available June. Box 454, SCIENCE.

6/13

Zoologist: Ph.D., eight years experience, desires summer teach-ing, zoology, biology, physiology. Box 485, SCIENCE. X

YOU reach over 32,000 scientists inthese columns at a very low cost

|||||||||||||||||||||||||||||||| POSITIONS OPEN

Assistant Pathologist: starting immediately-500 bed general hos-pital affiliated with State University Medical School. Write: Di-rector, Laboratories, Maimonides Hospital of Brooklyn, 4802 TenthAvenue, Brooklyn 19, New York. 4/20

Positions Open:(a) Biochemist to join cancer research group; Southwest. (b)Product Development Man; Ph.D. or Master's in pharmacy orexperience in developing new pharmaceuticals required; south.(c) Pharmacologist or Bacteriologist, Ph.D. or M.D.; laboratoriesconcerned principally with development of new antibiotics andantibiotic dosage forms, East. (d) Medical Bacteriologist; pre-ferably Ph.D., research laboratories, industrial company; West.(e) Assistant Medical Director; duties include medical writing,clinical investigation; East. (f) Bacteriologist; Ph.D., to directresearch division, pharmaceutical company; knowledge of growthof bacteriology, moles used in penicillin required; $8000. (g) As-sistant or Associate Professor of Anatomy; full-time; universitymedical school; East. S4-2 Science Division, Medical Bureau,(Burneice Larson, Director) Palmolive Building, Chicago. X

14

-The MARKET PLACEBOOKS * SERVICES * SUPPLIES * EQUIPMENT

llllllllijlllllllIll]]l^IjIIIIiII BOOKS 1!011111111111Send us your Lists of tf

SCIENTIFIC BOOKS AND PERIODICALSwhich you have for sale.

Complete libraries; sets and runs; and single titles are wanted

Also please send us your want lists.STECHERT-HAFNER, INC., 31 East 10th Street, New York 3

Your sets and files of scientific journalsare needed by our library and institutional customers. Please send

us lists and description of periodical files you are willing to sel

at high market prices. Write Dept. A3S, J. S. CANNER, INC.Boston 19, Massachusetts

WANTED TO PURCHASE:SC I ENTI F IC PE R IO D I CA LS

Sets and runs, foreign and domesticSC I ENT IF IC BOOKSEntire libraries and smaller collections

WALTER 1. JOHNSON125 East 23rd Street, New York 10, N. Y.

|IDIIDIIIIiIIII|~PROMSSION SERVICES

tBSPECIAL GLASS APPARATUSOurglass blowing department is available for special

scientific and technical glass apparatus made tospecifications and drawings. Inquiries invited.Estimates furnished.

E . M A C H L E TT & S O N218 East 23rd St. Now York 10, N. Y.

FOODRESEARCH o~ RESEARtCH

H ~~~~~Fouwed 1922h0lp L Nowi. P.., Wa CONSULTATIONV~~~~~~Snr L Osw, Ph.D., DlscoReIt^h * Analysff * Consluelion

Biologicaol, Nutritiona l, Toxicolog ica l Studies *~ANALYSES_for th* Food, Drnug and Allied Industries48-14 33rd Stoet, Long Isl_d lty 1, N.Y.

THE PAN RAY CORP.Reserch Diviston

340 CANAL ST., NEW YORK 13

* Microanalysis (C, H, N, S, Etc.)* Custom Organic Synthesesi* Chemotherapeutics

0 Sponsored Research

SCIENCE, Vol. 113-

YOUR ad here reaches over 32,000 foremost scientistsin the leading educational institutions, industriallaboratories, and research foundations in the U. S.and 76 foreign countries -at a very low cost

CLASSIFIED: 200 per word, minimum charge $5.00. Use ofBox Number counts as 10 additional words. Correct pay-ment to SCIENCE must accompany ad.

DISPLAY: Rates listed below-no charge for Box Number.Monthly invoices will be sent on a charge account basis-providing satisfactory credit is established.

Single insertion $17.50 per Inch7 times In 1 year 16.00 per inch13 times in 1 year 14.00 per inch26 times in 1 year 12.50 per Inch52 times in 1 year 11.00 per inch

For PROOFS on display ads, copy must reach SCIENCE 4weeks before date of issue (Friday of every week).

The MARKET PLACE1TBOOKS * SERVICES * SUPPLIES * EQ2UIPMENT |

L|IANGUAGES 1llllllllll!lllIIIIIIIIII

It's Quick, Easy Fun to Learn a Language by LINGUAPHONEAt home lear to speak Spanish, French, German, R n theOriental languages by quick easy Linguaphone ConversationalMethod. Save time, work, money. Send for fr book today.

Courses approved for VETERANS' TrainingLINGUAPHONE INSTITUTE * 8404 REskefellsr Plaa, Mlmw York 20

|||||||||||||||SUPPLIES AN,.D EQUIPMENTs||||||||||||||

White SWISS Mice 20c upRabbit, Cavies, Whit. Rats, Ducks, Pigeons, HanmstrsWrite * J. B. STOCKER * Batsaey, N. J.

* Important Microscopic* Teaching Supplies .. .* Comparative Micro-anatomical, and Zoolocal Prep

arations for the Premedic Medical, an raduate* Students,the Teaching and Medical Professions.

Descriptive Circulars mailed on request.THE AGERSBORG BIOLOGICAL LABORATORY

H. P. K. Agersborg, Ph.D., Owner * Telephone 6531511 City National Bank Bldg. * Centralia, Illinois

L-PROLINE-Hydroxyproline, L-Methlonineo AMINO( ACIDS * BIOCHEMICALS* PRE-MIXED MICROBIOLOGICAL ASSAY MEDIA

H. M. CHEMICAL COMPANY, LTD.144 North Hayworth Avenue Los Angeles 48, C if

New Food Igredients* New DrugsETga ANIMAL TESTS

- 'w AAnlyses*C-sulbaiom* Researche I LaWaN & Harrissoncmi - Pk_badists Div. S, 1921 WAniltSt. PUadelPlbia 3, h.

SUPPLIES AND EQUIPMENT17

SAF-T-GRIPBEADED EDGE

MICROSCOPENON-CORROSIVE 0

SLIDESNON-FOGGING

* Smooth, diamond-procesed beaded edge-won't slip orslide from hand-elminates cuts from sharp edges.

* Made from water-clear glass-entirely free from flaws-guaranteed non-corrosive.

* Available in two types-plain or with frosted end foreasy marking.

* Economical-even as compared with ordinary sharp-edgedslides.

Write for prices, further information and samples.

PROPPER MANUFACTURING CO., INC.10-34 44th Drive, Long Island City 1, New York

* HYPOPHYSECTOMIZED RATSShipped to all points via Air Expres

For further information writeHORMONE ASSAY LABORATORIES, Inc. *808 E. 58th St.

Chicago 37, IIL.

ROGER** 70% TRANSMISSION* 30% REFLECTION

PASTS - SCIENCEROLAB LABORATSIIESSandy Hook, Connecticut* Formerly with Dr. Alexis

April 13, 1951

All Amino Acids (natural, synthetic, unnatural),Rare Sugars, Biochemical Products, Reagents, New Pharma-ceuticals in stock. Write or phone PLaza 7-8171 for completeprice list.BIOS LABORATORIES, INC. NeW 60th Street,

* RARE 1STA COMMONIAI 1 fl.J Price list on Request

STARKMMAN BIl Id*iY Toronto, Canada

INDEX of REFRACNON LIQUIDSI Valuable Aid for Identification of Minerals and other

* Solids by the Imnwrsion Method of MicroscoyI Range 1.400-1.700, Intervals of 0.002, or as selected

Index Certified to ± 0.00020 Range U171-1.83, intervals of 0.01

Writ for Priee List Nd-SR. P. CARCILLE 118LISbrty Street, New York 6, N. Y.

-

15

gmn

new!

PITUITARY-ADRENAL FUNCTION6 x 9 inches, illustrated, clothbound, 224 pages-$4.00Price to AAAS members for prepaid orders-$3.50

PITUITARY-ADRENAL FUNCTION continues the AAAS tradition of pre-senting in book form the collected papers presented at symposium programs of wideinterest. This volume includes 22 papers delivered at a two-day Symposium on theAdrenal Cortex at the AAAS meeting in New York City, December 1949.

PITUITARY-ADRENAL FUNCTION assembles important contributions of ascore of laboratories in the United States and Canada from which many of the recentmajor advances in pituitary-adrenal physiology and therapeutics have come, and in-cludes studies on the regulation of adrenal cortical activity, the role of the corticalhormones in protein, carbohydrate, and mineral metabolism, and effects of the eorticalsteroids and the ACTH in various disease states. A summary chapter on "Adrenol-escence" by Dr. George Perera forecasts some of the possible future trends in this activefield of endocrine research.

RiDg.-t- AAAS PUBLICATIONS * 1515 Mass. Ave., N.W., Washington 5, D. C.

Enclosed is $ . Please Accept my order for copy of PITUITARY-ADRENAL FUNCTION.

NAMEPlease Print

STREET

CITY ZONE STATE

ISciwou, Vol. 11316

'Will1 be dlsp' lb- at

the . I Of

tat Biology i'Cleveland. Among.

these wiltI b

illustra ted

A tso o'n ill be

-Struments for cvil dnse against-

radiation, including the on-ly moani-

tor which has been approved by the

Federal Civil Defense Administra-

tion.

77

NEW Autosaler for automaticurements of radioacfivity.

NEW ProportionalTubo for seletive

measuremenf ofalpha and bot.jrodiioNo.

NEW La-boratory Monitor for checkingcontamination and labatory back-ground.

--

v

.0- B 0-

*.Na-wD

- 4 -g

- WA* .:s

.fy

. ' . b; *."

OwSS 6 J

5,0.*,e, t ,' _s

.. e.0

m^s. X

.0

..... . ! . .',,:. .

,> - i.

_ ''''-

..,.,;. t '_

.

,- ,_.,....':_,:'

- . 4',:d'. ;it

- t.X_FK i7L';.: .K

Lf'-:-

W. "'

.ws --_d.i;;t

_ S,_, - -E'!s >' ,]S,,.',.* i'.'.

.MS:.

.,

.Di>,'

ss

-

/_.

R SCHO,LAtWS Alat oN'l

BETTER 4 WAYS FOR TEACHING

W .-l _.1qrJeem-AW Vi

blew.h~s.bsr,n.- I,,g.assand .bel

'a- Urn -

toowato n ntos.... ott_

free for teaching-Sciewee.-Sil con-t-rols permit moreVpid operion

A lPriMsSd.uilb

Standard qualitySpenceT-r trade-marked optiia Pre-4seslLmelbearng

twCodtotUy d

Locked-in pas re-duce maintenancecosts-Spisgloaced'focusi ismprotec sld

$109.00 \(For IOOX- 430X

as illuistrated)

F

* Spencer, No. 78 ScholarQsMicroscope, with built-iafaLctory-focused light sourcefuriilshes constant, aIniformillumination and consequentlybetter optical performance.Time-consuming and fre-quently faulty sub-stage dust,.Iments are eliminated.R-e-R--

versed position of microarm offers dear view o* s ,objectives, and diaph_-#openings. Low over-all hi -itinaceases comfort Trime-sav.:ing single conrol pwvzds

i rtapid yet critical foc A.IyourA DistributortosbC w.

you the No. 78 Miape.-.or wnte for og M153-toDept. R2.

i4dv: eH9'cantI*wi~~e4Awnen4 /* one. .. x,. , 5j