Citrate

Isocitrate

2-Oxoglutarate

Succinyl-CoA

ACETYL-CoA

PYRUVATE

iP

+

GTP

Glucose-6-P

Fructose-6-P

Fructose-1,6-bis- P

2 Triose-P

1,3-bis-P-Glycerate

3-P-Glycerate

2-P-Glycerate

ATP

ATP

ADP

ADP

NAD2 Pi NADH+H+

ADP

ATP

H2OADP

ATP

P-enolpyruvate

PYRUVATE

Oxaloacetate

Malate

H H

GLUCOSE

2

2

2

2

22

2

22

2

2

2

GLYCOLYSIS & TCA CYCLE-

Fumarate

Succinate

GDP

ADP

ADP

ATP

ATP

ATP

AMP

Fructose-2,6-bis-P

INSULIN

HIGH BLOOD GLUCOSE

not in liver

REGULATION

NADH+H+

Designed by Donald Nicholson c 2002 IUBMB