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A WINNING PROPOSITION FOR RESEARCH, DEVELOPMENT & INNOVATION

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Page 1: A WINNING PROPOSITION FOR RESEARCH ...š A WINNING PROPOSITION FOR RESEARCH, DEVELOPMENT AND INNOVATION 05 IDA Ireland plays a leading role in RD&I development by providing funding

WWW.IDAIRELAND.COM A WINNING PROPOSITION FORRESEARCH, DEVELOPMENT &INNOVATION

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CONTENTS˚01_ IRELAND - A PRIME LOCATION FOR RD&I02_ HOW IRELAND DELIVERS ON ITS RD&I PROMISES03_IRELAND’S RD&I FRAMEWORK04_THE IRISH ADVANTAGE

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The Irish Government is focused on driving economic growth by encouragingfurther RD&I activities. Its strategic objectives are backed with positive action through an unprecedented investment of €8.2 billion under the Government’s strategy for Science Technology and Innovation. This funding is already building a world class research system. The science strategy is also ensuring that all elements are working in unison for the benefit of industry. It is the “Smart Economy” made real.

Today’s Ireland offers a strong, growing RD&I environment - complemented by arobust Intellectual Property (IP) regime; a young skilled and well-educated workforce with strong technological and business skills; and a low corporation tax.

The Drivers of Global RD&I› Access to the best talent, research and technology› Convergence between previously separate industries › The rate of continuous innovation required to keep pace with new business models› Research “hotspots” and “networks” that support and encourage RD&I

01_IRELAND – A PRIME LOCATION FOR RD&I

In every area of the contemporary business world, progressive companies face an ever-increasing demand to innovate. This drive for advancement is one of the main catalysts for the internationalisation of Research, Development and Innovation (RD&I).

Ireland is now considered one of the leading RD&I locations in the world. Ireland has the capacity to meet the needs of RD&I investors and offers the ideal commercial, political and social environment in which to carry out successful and profitable RD&I activities.

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IRELAND˚ A WINNING PROPOSITION FOR RESEARCH, DEVELOPMENT AND INNOVATION 03

+_IRELAND: yOu ARE IN GOOD COMPANy

What Ireland Offers› A pro-business environment with a 12.5% corporate tax rate› A long-established track record of working with multinational

corporations (MNCs)› Strong Intellectual Property protection› Well-established collaboration between a world-class academic sector and industry› A highly-skilled workforce with strong managerial and communication abilities› Support and access to Government funding and RD&I networks through IDA Ireland and Science Foundation Ireland› Excellent business infrastructure and Information and Communications Technology (ICT)

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Collaborative Research EnvironmentA unique feature of the Irish business environment is the productive collaboration between industry, academia and government agencies. All stakeholders work together, building a national team to consolidate Ireland’s position as a knowledge-based economy and as a primary location for RD&I.

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02_HOW IRELAND DELIVERS ON ITS RD&I PROMISES

Ireland’s RD&I Landscape

ResearchCentres

Government Agencies

Education/ Third Level

GovernmentDepartments

Regulation

Industry

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IRELAND˚ A WINNING PROPOSITION FOR RESEARCH, DEVELOPMENT AND INNOVATION 05

IDA Ireland plays a leading role in RD&I development by providing funding support to suitable projects, and by identifying other supports available from partner organisations such as Enterprise Ireland, Science Foundation Ireland, and Sustainable Energy Ireland.

In addition to RD&I funding, IDA Ireland has a number of directsupport mechanisms, including employment and training grants.Through its property portfolio, IDA also has a suite of property offerings for companies.

IDA Ireland works closely with companies to ensure they have the facilities, resources and support they need to establish and expand their RD&I operations. IDA helps ensure these progressive companies continue to flourish here as key drivers of Ireland’s future economic success.

A Comprehensive Range of RD&I Programmes› IDA Ireland’s RD&I Programme, and Feasibility and Training Support› Enterprise Ireland’s Innovation Partnerships Initiative› IDA Ireland/Enterprise Ireland Competence Centres

› SFI Centres for Science, Engineering and Technology (CSET) Programme

› EU 7th Framework Programme for Research and Technological Development (FP7)

+_WORKING WITH yOu AND OTHERS

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Centres for Science, Engineering and Technology (CSET’s)These centres are funded by Science Foundation Ireland and are formed by clusters

of internationally competitive researchers from the third-level sector and industry.

Their purpose is to exploit and develop opportunities in science‚ engineering and

technology; in particular research that underpins developments in Biotechnology‚

ICT and Renewable Energy sectors.

A notable example is the Centre for Research on Adaptive Nanostructures &

Nanodevices (CRANN), located at Trinity College Dublin. The aim of CRANN is to

deliver world class research and innovation in nanoscience and nanotechnology

which will address key industry challenges. CRANN is a critical component of an

integrated national strategy to transition Ireland to a knowledge economy.

CRANN’s industrial partners include Intel and H.P, with both companies having

researchers-in-residence in the CRANN facility.

RD&I Competence Centres These are collaborative entities established and led by industry. They are resourced

by highly-qualified researchers associated with research institutions who undertake

market focused strategic RD&I for the benefit of industry.

An RD&I Competence Centre is formed when a group of companies come together

to define their common research interest. The group then submits an expression

of interest to IDA Ireland or Enterprise Ireland outlining areas of common interest,

market presence and the strategic impact of a competence centre on their business

model. Expressions of interest that show highest potential impact will be selected to

progress for government funding. Participating companies must be open to working

with likeminded companies and prepared to collaborate with research performers.

Multinational companies that have participated to date include Medtronic, Intel,

Xilinx, Seagate, Analog Devices, DePuy and Bombardier Aerospace.

The National Institute for Biotechnology Research and Training (NIBRT) NIBRT is an IDA-supported collaboration between four leading Irish academic

institutions. Its purpose is to deliver state-of-the-art training/learning facilities and

research solutions for the advancement of the BioPharma sector in Ireland.

+_ExamplEs of RD&I pRogRammEs

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+_OTHER ELEMENTS INFLuENCING RD&I IN IRELAND

Irish enterprise policy is focused on creating a smart economy for Ireland; an economy which has at its core an exemplary research, innovation and commercialisation ecosystem.

Key Elements of IDA Ireland’s RD&I Strategy › Leveraging recent investment by the Irish Government in RD&I to support, develop and encourage multinational corporations (MNCs) to undertake RD&I in Ireland› Fostering an environment of collaboration between government, academia and MNCs› Ensuring RD&I policies are business friendly and attractive to MNCs› Promoting Ireland as a location for carrying out world-class RD&I

07IRELAND˚ A WINNING PROPOSITION FOR RESEARCH, DEVELOPMENT AND INNOVATION

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Ireland offers a world-class research development and innovation (RD&I) model that delivers success for global companies like AON, Intel, PayPal and Boston Scientific.The following sections explain how Ireland recognises the optimum conditions needed for these companies to flourish in the global RD&I environment.

03_IRELAND’s RD&I FRAMEWORK

Key Elements of Ireland’s RD&I Success› A strong commitment and focus by the Irish Government to RD&I› Irish legislation provides MNCs with incentives to generate qualifying patents – up to €5 million annual qualifying income can be exempt from Irish tax› R&D tax credit – designed to encourage companies to undertake new or additional R&D activity in Ireland. The tax credit covers wages, plant/machinery, buildings and related overheads of establishing an RD&I activity in Ireland› A tax rate of 12.5% applies to all corporate trading profits› Clusters of global leaders in key high tech industries including Pharmaceuticals, Medical Devices, Biotechnology, ICT and Financial Services

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IRELAND˚ A WINNING PROPOSITION FOR RESEARCH, DEVELOPMENT AND INNOVATION 09

THE STANDALONE MODELIn this model, a company establishes a dedicated centre to support either corporate research or an innovation agenda through a standalone facility in Ireland.

THE COLLAbORATIVE MODELThe Collaborative Model describes an RD&I investment that is co-dependent on a substantial collaborative engagement with an Irish or international academic institution – and/or with a MNC or indigenous Irish company. You could call it a meeting of minds and cross-discipline brainpower.

DEVELOPMENT & MANuFACTuRING/ SERVICE DELIVERy MODEL This refers to RD&I done at a manufacturing or service delivery site that improves the manufacturing or service delivery process to achieve greater productivity, efficiency and quality of the operation or service.

THE DEVELOPMENT & COMMERCIALISATION MODELThe Development & Commercialisation Model relates to instances of RD&I investments where the outputs will be developed and produced in Ireland for export markets.

+_FOuR MODELS FOR RD&I

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Standalone Success in RD&IIreland has proven itself a successful location for companies wishing to establish standalone RD&I. As part of their overall RD&I strategy and complimented by the skillsets of Irish researchers, a wide range of global companies have successfully managed to capture first-mover advantage in innovation, product development and design by setting up RD&I Centres of Excellence in Ireland.

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*THE STANDALONE MODEL

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CASE STuDIES

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CASE STuDIES

Cisco A worldwide leader in networking and collaboration products and services, Cisco invested in a dedicated site for 250 research and development staff in Galway City. From the outset, the Galway initiative has established a global leadership mandate in Cisco’s Unified Communications and Collaboration (UCC) portfolio. Research conducted here is at the very heart of Cisco’s strategy in empowering ‘The Human Network’. The project has established strong research partnerships and linkages with the Science Foundation Ireland (SFI) funded CSET at the Digital Enterprise Research Institute (DERI) in University College Galway, and with the Telecommunications Software & Systems Group (TSSG) in Waterford Institute of Technology (WIT). The Galway facility is also host to a European UCC customer briefing centre enabled by Cisco’s TelePresence video technology.

AON In financial services, product and process innovation is now a core activity in drivingthe strategic importance of the Irish operations. AON - providers of risk managementservices, insurance and reinsurance brokerage - created an industry-first when choosing Dublin as the location for a Global Centre of Excellence. The Centre will systematically aggregate information from around the world using sophisticated mathematical and analytical techniques, which Aon will translate into real-time insights and innovative insurance products and risk solutions tailored to clients needs. This Centre of Excellence provides advanced research and development technology, enabling the firm to drive product, process and business model innovation across several disciplines.

Helsinn Helsinn, a privately owned pharmaceutical company, has established a Centre ofExcellence in Research and Development for Oral Solid Dosage (OSD) at its Dublin facility, Helsinn Birex Pharmaceuticals. Helsinn’s core business is the in-licensing oflate stage pharmaceutical compounds in therapeutic niche areas for developmentand subsequent commercial manufacture and distribution. The company is primarilyactive in oncology supportive care, anti-inflammatory and gastrointestinal treatments.The investment is part of Helsinn’s strategic decision to strengthen its in-housedevelopment capabilities. The Helsinn investment will establish the Irish operation as the centre of knowledge and learning for OSD products in the Helsinn Group, and the launch site for new products within its portfolio. This investment puts the Irishoperation at the core of Helsinn’s R&D activities.

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Ireland’s Collaborative Business CultureCollaboration between industry and third level institutions has become an important component of the Irish RD&I landscape. More and more companies are forming industry/academic alliances to share costs and avail of the unique skills available in research-performing academic institutions in Ireland.

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*THE COLLAbORATIVE MODEL

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CASE STuDIESCASE STuDIES

GlaxoSmithKline GlaxoSmithKline (GSK) is one of the largest pharmaceutical companies in the world. In its Irish RD&I operations, GSK is developing a ground-breaking research project into gastrointestinal diseases, in collaboration with the Alimentary Pharmabiotic Centre (APC) in University College Cork. This project is jointly supported by IDA Ireland and Science Foundation Ireland (SFI). The company is also investing in a unique collaboration with the Trinity College Institute of Neuroscience (TCIN) and the National University of Ireland (NUI) Galway on a major Research & Development programme for the discovery of new therapies to treat Alzheimer’s Disease.

Intel The Irish campus is home to Intel’s IT Innovation Centre which is involved in far-reaching research & development of applications including peer-to-peer networks, digital health, mobility solutions, education deployment technologies (including wireless & satellite) and e-learning architectures and platforms. The Irish operations have responsibility for the direct management and governance of Intel’s innovation labs across Europe. Intel also has an operation in Shannon, Co Clare designing advanced microprocessors for use in embedded computing communications and storage markets. Intel recently announced the expansion of this operation involving industrial research in silicon design and validation and the development of a content processor module. Intel is collaborating in this area with the Centre for Research on Adaptive Nanostructures & Nanodevices (located at Trinity College Dublin), the Tyndall National Institute in Cork and the National University of Ireland in Maynooth.

Smith & Nephew Smith & Nephew, the global medical technology company, and REMEDI, the Regenerative Medicine Institute at NUI Galway, established a four year R&D collaborative programme for the development of treatments for bone and jointdiseases. The Smith & Nephew Research Centre in York, United Kingdom, is working in partnership with REMEDI to develop new therapies using adult bone marrow stem cells to promote the re-growth of healthy cartilage and the repair of damaged joints. REMEDI, recognised as Ireland’s primary centre for stem cell and gene therapy research, was established as a Centre for Science, Engineering and Technology (CSET ) in 2004 by Science Foundation Ireland. It has a core expertise in arthritis research and a particular emphasis on the translation of its research findings to the delivery of new therapies in orthopaedics, cardiovascular and neural diseases.

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The Development and Manufacturing/Service Delivery Model refers to RD&I carried out at a manufacturing or service delivery site that improves the manufacturing or service delivery process to achieve greater productivity, efficiency and quality of the operation.

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*DEVELOPMENT & MANuFACTuRING/SERVICE DELIVERy MODEL

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Stryker InstrumentsStryker Instruments, part of the Stryker Corporation, is known for a wide rangeof innovative operating room products - from surgical power tools to advancedsystems for waste management, irrigation, personal protection and pain management.Established in 1998, Stryker’s Cork plant has successfully developed a state-of-the-artresearch and development and manufacturing facility for minimally invasive surgicalinstruments. These products are used for cutting, drilling, burring and shaping of bone and soft tissue during orthopaedic, spine, ear, nose and throat plastic surgery. The R&D team in Cork is involved in both product and process development with sole responsibility for the development, pilot manufacturing, regulatory approvaland commercial manufacture of disposable bone and soft tissue cutting instruments.

MerckMerck established its first Irish operation in Co. Tipperary in 1976. The constructionof a new 200,000 sq ft facility in Ireland when complete, will enable all the unit processes to manufacture final stage (Phase III) clinical trial solid dosage (tablets & capsules) for global clinical trials. The facility will be used to manufacture, market and launch quantities of newly approved drugs prior to their manufacture in long term supply sites. Significant parts of this operation will have a large R&D element involved in new process development including Process Analytical Technology and in-process measurement systems, tablet & capsule formulation development, and the development of new analytical methods for each new medicine.

PaypalPaypal, an eBay company, set up their European Operations Centre (EOC) in Dublinin 2003, serving markets in Italy, France, Germany, Spain, UK, Netherlands and Poland. Paypal Ireland now employs some 900 fulltime staff across it portfolio of activities such as European Customer Services, Risk & Fraud Management and Merchant Solutions. The company recently initiated a Customer Centre of Excellence which will see the EOC evolve into an operation with responsibility for developing Customer Service and Operational Excellence within the PayPal Group. The Centre of Excellence will be involved in re-engineering the end-to-end customer experience – working across European operations and with the company’s European Business Units to define and implement innovative solutions in product, process, policy and technology; a significant upward move in relation to value added activities. PayPal’s Centre of Excellence will be working with the Innovation Value Institute in the National University of Ireland at Maynooth.

CASE STuDIESCASE STuDIES

IRELAND˚ A WINNING PROPOSITION FOR RESEARCH, DEVELOPMENT AND INNOVATION 15

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Commercialisation is the successful implementation of a novel idea into something of value to the marketplace. The successful commercialisation of new products or services in Ireland can lead to increased revenue, market share, and profitability.Ireland has a strong track record of companies developing and delivering new products and services to the market across a wide sectoral range.

*THE DEVELOPMENT AND COMMERCIALISATION MODEL

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AnalogThe focus of Analog’s Irish operation is to produce quality precision products throughprecision manufacturing, while exploiting cost-efficiencies. Innovation is fosteredthrough teamwork, both within the Irish operation and through cross-nationalresearch teams throughout Analog Devices globally. The company has recentlyupgraded its wafer manufacturing facility in Limerick moving from a 6˝ fab to an 8˝ fab. The Limerick based R&D team of over 400 engineers are involved in IC layout,Analog design (custom transistor level design), Digital/ASIC design, system design,product/test engineering and semiconductor process technology. Access to R&D andhighly skilled manufacturing and technological experts allows the Ireland operationdevelop an average of 80 new products each year. The Irish R&D team has soleresponsibility within Analog for the global design, manufacture and supply of valueadded high voltage mixed signal CMOS products. Boston Scientific Boston Scientific specialises in manufacturing medical devices for use in minimally invasive surgical procedures. The company set up its first operation in Ireland in 1994, in Galway. The Galway facility is the company’s largest operation in Ireland, manufacturing cardiology related products – stents, catheters and guidewires. This operation also has one of the largest R&D teams in Ireland. Boston Scientific has recently announced an RD&I investment at its Cork facility reflecting the enhanced capability of this facility for the development and commercialisation of next generation products to treat neurovascular diseases of the brain, including coils, intracranial stent delivery systems and access devices. Boston Scientific Corporation currently employs 5,000 people in Ireland.

Medtronic Medtronic has been present in Ireland since 1999. Medtronic’s Galway site is a Centreof Excellence for the development and manufacture of key medical technologies inthe treatment and management of cardiovascular and cardiac rhythm diseases, employing over 2000 people in Ireland working at state-of-the-art facilities in Galway. This figure includes over 90 Research & Development personnel working on a number of high value projects such as the development of next generation cardiovascular products and Cardiac Rhythm Disease Management delivery systems. A large proportion of the products manufactured at Medtronic’s Galway site result from R&D carried out at the facility. The company also maintains R&D links with many third level institutions throughout Ireland as the country’s academic climate gives it access to highly-trained medical technology research and development experts.

CASE STuDIESCASE STuDIES

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Ireland is a proven location for RD&I with a successful track record across multiple industry sectors, based on the unique combination of benefits on offer to global business:

› A stable political environment and respected regulatory regime› A pro-business environment with a 12.5% corporate tax rate, tax credits for RD&I activities and an extensive double tax treaty network with 51 countries› A high-skills, knowledge-based economy delivering quality, highly productive employees with excellent technical, managerial and multilingual customer service skills› A reputation for flexibility, responsiveness and innovation› Forty years’ experience working with MNCs to establish and expand operations across a wide range of sectors› Clusters of global leaders in key high tech industries including pharmaceuticals, medical devices and ICT› Experienced and innovative leaders focused on proactively identifying and solving business challenges› Strong Government support for RD&I focused on highly productive alliances between industry and academia› Excellent legal expertise for the commercialisation and protection of intellectual property rights

04_THE IRISH ADVANTAGE

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19IRELAND˚ A WINNING PROPOSITION FOR RESEARCH, DEVELOPMENT AND INNOVATION

+_CONTACT IDA IRELAND

IDA Ireland offers information, advice and ongoing support to companies setting up or expanding RD&I operations in Ireland.

IDA Ireland is Ireland’s inward investment promotion agency. The agency works with companies to secure new investment and collaborates with existing foreign investors in Ireland to help expand and develop their businesses. To learn more log on to www.idaireland.com or contact any IDA office.

Headquarters IDA Ireland, Wilton Place, Dublin 2, Ireland.Tel: +353 1 603 4000 Fax: +353 1 603 4040e-mail: [email protected]: www.idaireland.com

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+_IDA GLObAL OFFICE NETWORK

IRELAND India501, 5th Floor,Blue Wave Building,B/h Kuber Complex,Off Oshiwara Link Road,Andheri (West),Mumbai-400 053 Tel: +91-22-42178900 Fax: +91-22-42178999

Japan Ireland House 2F2-10-7 KojimachiChiyoda-KuTokyo 102-0083Tel: +81 3 3262 7621Fax: +81 3 3261 4239

Korea 13th Floor Leema B/D146-1 Susong-dong, Jongro-kuSeoul 110-755Tel: +82 2 755 4767/8Fax: +82 2 757 3969

Taiwan 7FL-12, No.41Nanking W. RoadTaipei 103TaiwanTel: +886 2 2552 6101Fax: +886 2 2550 7220

AthloneAthlone Business &Technology ParkGarrycastle, Dublin Rd.AthloneWestmeathTel: +353 (0) 90 64 71500Fax: +353 (0) 90 64 71550

CavanIDA Business ParkDublin RoadCavanTel: +353 (0) 49 436 8820Fax: +353 (0) 49 433 2047

CorkIndustry HouseRossa AvenueBishopstownCorkTel: +353 (0) 21 480 0210Fax: +353 (0) 21 480 0202

DonegalPortland HousePort Road, LetterkennyDonegalTel: +353 (0) 74 916 9810Fax: +353 (0) 74 916 9801

DundalkFinnabair Business ParkDundalkLouthTel: +353 (0) 42 935 4410Fax: +353 (0) 42 935 4411

Galway Mervue Business ParkGalwayTel: +353 (0) 91 735 910Fax: +353 (0) 91 735 911

LimerickRoselawn HouseNational Technology ParkLimerickTel: +353 (0) 61 200 513Fax: +353 (0) 61 200 399

SligoFinisklin Business ParkSligoTel: +353 (0) 71 915 9710Fax: +353 (0) 71 915 9711

WaterfordWaterford Technology ParkCork RoadWaterfordTel: +353 (0) 51 333 055Fax: +353 (0) 51 333 054

FranceMaison d’Irlande33 rue de Miromesnil75008 ParisTel: +33 (0) 1 43 12 91 80Fax: +33 (0) 1 47 42 84 76

GermanyFBC Frankfurter Büro CenterMainzer Landstr. 4660325 Frankfurt am MainTel: +49 (0) 69 706099-0Fax: +49 (0) 69 706099-70

AtlantaMonarch Plaza,Suite 3503414 Peachtree Road,N.E., Atlanta,GA 30326Tel: +1 404 816 7096Fax: +1 404 846 0728

Boston31 Saint James Avenue, 7th Floor, Boston, MA 02116.Tel: +1 617 357 4190Fax: +1 617 357 4198

California3 Park Plaza, Suite 430, Irvine, CA 92614.Tel: +1 949 748 3547Fax: +1 949 748 3586

800 W. El Camino RealSuite 450,Mountain View, CA 94040Tel: +1 650 967 9903Fax: +1 650 967 9904

RussiaEmbassy of IrelandGrokholski Pereulok 5Moscow 129010Tel: +7 495 937 5911Fax: +7 495 680 0623

United Kingdom Shaftesbury House151 Shaftesbury AvenueLondon WC2H 8AL Tel: +44 (0) 20 7379 9728Fax: +44 (0) 20 7395 7599

BrazilAv. das Nações Unidas,12551 - 17 andar04578-903 S. Paulo - SPBrazilTel: +55 11 3443 7080Fax: +55 11 4992 0406

AustraliaIreland HouseSuite 2601, Level 261 Market StreetSydney NSW 2000Tel: +61 (0)2 9273 8524Fax: +61(0)2 9273 8527

ChinaSuite 655Shanghai Centre1376 Nanjing Road WestShanghai 200040Tel: +86 21 6279 8500Fax: +86 21 6279 8505

EUROPE

USASOUTH AMERICA

ASIA-PACIFIC

Chicago77 West Wacker DriveSuite 4070Chicago, IL 60601-1629Tel: +1 312 236 0222Fax: +1 312 236 3407

New York345 Park Avenue, 17th FloorNew York, NY 10154-0004Tel: +1 212 750 4300Fax: +1 212 750 7357

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WWW.IDAIRELAND.COM A WINNING PROPOSITION FORRESEARCH, DEVELOPMENT &INNOVATION

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