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Index

Supplementary Table S1: Validated HTT interacting proteinsSupplementary Table S2: Genes identified to alter HD pathogenesis in Genome wide knock down screen Supplementary Table 3: Co-expression of genes with Wild type HTT (http://coxpresdb.jp) Supplementary Table S4 : Wild type HTT coexpressed genes (http://www.GeneFriends.org)Supplementary Table S5A: Decreased expression of genes in the caudate of HD with p≤0.001 (Hodges et al. 2006)Supplementary Table S5B: Increased expression of genes in the caudate of HD with p≤0.001 (Hodges et al. 2006)Supplementary Table S6: HD associated genes collected from various resourcesSupplementary Table S7A: Enriched Biological processes with HD associated genesSupplementary Table S7B: Enriched Biological pathways (KEGG) with HD associated genesSupplementary Table S7C: Enriched Cellular component with HD associated genesSupplementary Table S8A: HD associated genes with TVSSupplementary Table S8B: HD associated genes that are konown targets of FDA approved drugsSupplementary Table S8C: HD associated genes that are potenial targets Supplementary Table S8D: HD associated genes that are potenial targets with TVS Supplementary Table S8E: HD associated genes that are FDA approved drug targets with TVS Supplementary Table S8F: HD associated proteins without TVS but either known targets of FDA approved drug or potential drug tSupplementary Table S9A: Biological Processes and KEGG pathways connected with HD associated genes with TVS and targets of FDA approvSupplementary Table S9B: Biological Processes and KEGG pathways connected with HD associated genes without TVS and targets of FDA app

Sheet 2Sheet 3sheet 4sheet 5

Supplementary Table S5A: Decreased expression of genes in the caudate of HD with p≤0.001 (Hodges et al. 2006) sheet 6Supplementary Table S5B: Increased expression of genes in the caudate of HD with p≤0.001 (Hodges et al. 2006) Sheet 7

Sheet 8sheet 9sheet 10sheet 11sheet 12sheet 12sheet 12sheet 12sheet 12

Supplementary Table S8F: HD associated proteins without TVS but either known targets of FDA approved drug or potential drug tsheet 12Supplementary Table S9A: Biological Processes and KEGG pathways connected with HD associated genes with TVS and targets of FDA approvSheet 13Supplementary Table S9B: Biological Processes and KEGG pathways connected with HD associated genes without TVS and targets of FDA appsheet 14

Supplementary Table S1 Table Validated HTT interacting proteinsSymbol Gene ID Other Symbol Name ChromosomeACADL 88 LCAD, ACAD4 acyl-CoA dehydrogenase,2q34ACADS 90 SCAD, ACAD3 acyl-CoA dehydrogenase,12q24.31ACTB 132 actin, beta [Source:HGN 7p22.1ACTN1 163 actinin, alpha 1 [Sourc 14q24.1ACTR1B 168 ARP1 actin-related prote 2q11.2ADD1 243 adducin 1 (alpha) [Sour 4p16.3ADD2 244 ADDB adducin 2 (beta) [Sourc 2p13.3ADD3 120 ADDL Gamma-adducin; ADD3 10q24.2-q24.3AHSA1 1189 p38 AHA1, activator of heat 14q24.3AIFM1 9131 AIF1 apoptosis-inducing factorXq26.1AKAP8 378 AKAP95, DKFZp58A kinase (PRKA) anchor 19p13.12AKAP8L 26993 NAKAP A kinase (PRKA) anchor p19p13.12AKT1 207 PKB RAC-alpha serine/threoni14q32.32ALDOA 414 aldolase A, fructose-bi 16p11.2AP1B1 554 BAM22, AP105A adaptor-related protein 22q12.2AP1G1 555 adaptor-related protein 16q22.2AP2A1 160 adaptor-related protein co19q13.33AP2A2 161 HIP9/HYPJ Adaptor-related protein 11p15.5AP2B1 563 adaptor-related protein 17q12API5 8539 AAC11 apoptosis inhibitor 5 11p11.2ARFGAP1 15852 FLJ10767, bA261N1ADP-ribosylation factor 20q13.33ARHGEF6 9459 COOL2 Rho guanine nucleotide Xq26.3ARNT2 9915 Arnt2 aryl-hydrocarbon receptor15q24ASPH 444 Aspartyl/asparaginyl bet 8q12.1ATP1A1 799 ATPase, Na+/K+ transpor1p13.1ATP1B1 804 ATPase, Na+/K+ transpor1q24.2ATP2A2 812 SERCA2 ATPase, Ca++ transportin12q24.11ATP5A1 823 ATP5A, hATP1, O ATP synthase, H+ transpo18q21.1ATP5B 830 ATP synthase, H+ transpo12q13.3ATP5C1 833 ATP synthase, H+ transp 10p14ATP5F1 840 ATP synthase, H+ transp 1p13.2ATP6V0A2 18481 TJ6, a2, TJ6s, TJ6 ATPase, H+ transporting 12q24.31ATP6V0E 8992 ATP6V0E1 V-type proton ATPase su5q35.1BAG1 573 BAG family molecular ch9p12BAIAP2 947 BAP2 BAI1-associated protein 17q25.3BCAN 23059 BEHAB, MGC13038brevican [Source:HGNC 1q23.1BCL11B 64919 CTIP2 B-cell CLL/lymphoma 11B 14q32.2BECN1 8678 ATG6 beclin 1, autophagy relate17q21BMP2K 55589 BMP-2-inducible protei 4q21.21BZW2 28969 HSPC028 Basic leucine zipper and 7p21.1CACNA2D1 781 CACNA2 Voltage-dependent calci 7q21-q22CALM1 801 CAM/CALM2?CALcalmodulin 1 (phosphoryla14q24-q31CAMK2B 1461 CAM2, CAMK2 calcium/calmodulin-depen7p13CAMK2G 1463 calcium/calmodulin-depe10q22.2

CAPRIN1 6743 caprin-1, RNG105 cell cycle associated pr 11p13CAPZA1 1488 capping protein (actin f 1p13.2CAPZA2 1490 CAPZ, CAPPA2 capping protein (actin f 7q31.2CAPZB 1491 capping protein (actin f 1p36.13CASP1 834 caspase 1, apoptosis-relat11q23Casp10 843 MCH4 caspase 10, apoptosis-rela2q33-q34CASP2 835 NEDD2/ICH1 Caspase 2, apoptosis-relat7q34-q35CASP3 836 CPP32 caspase 3, apoptosis-relat4q34CASP6 839 MCH2 caspase 6, apoptosis-relat4q25CASP7 840 MCH3 caspase 7, apoptosis-relat10q25CASP8 841 MCH5 caspase 8, apoptosis-relat2q33-q34CBS 875 HIP4 cystathionine beta-syntha21q22.3CCT2 1615 Cctb chaperonin containing T 12q15CCT4 1617 Cctd chaperonin containing TC2p15CCT6A 1620 TTCP20, TCPZ, Cctchaperonin containing T 7p11.2CCT8 1623 Cctq, PRED71 chaperonin containing TC21q21.3CDH13 1012 CDHH cadherin 13 16q23.3CHD3 1107 chromodomain helicase D17p13.1CHMP5 26942 HSPC177, CGI-34, charged multivesicular 9p13.3CLTC 1213 CHC clathrin, heavy chain (Hc)17q11-qterCNP 2158 2',3'-cyclic nucleotide 17q21.2CNTN1 2171 F3, GP135 contactin 1 [Source:HGN12q12COPB1 2231 coatomer protein comple 11p15.2CORO1B 2253 coronin-2 coronin, actin binding p 11q13.2CORO1C 2254 coronin-3, HCRNN4coronin, actin binding p 12q24.11COX4I1 2265 COX4-1 cytochrome c oxidase su 16q24.1COX6C 1345 cytochrome c oxidase sub8q22.2CPT1B 1375 CPTI Carnitine O-palmitoyltra 22q13.33CREBBP 1387 CBBP CREB binding protein 16p13.3CSDA 2428 cold shock domain prote 12p13.2CTBP1 1487 C-terminal binding protei4p16CTNNB1 1499 FLJ37923 catenin (cadherin-associat3p21

8453 Cullin 2 10p11.21CYC1 2579 UQCR4 cytochrome c-1 [Source 8q24.3DBN1 2695 drebrin 1 [Source:HGNC 5q35.3DCTN1 1639 dynactin 1 2p13DDB1 2717 XPE damage-specific DNA bin11q12.2DDX5 2746 p68 DEAD (Asp-Glu-Ala-Asp)17q23.3DHX15 2738 HRH2, DBP1, PRP43DEAH (Asp-Glu-Ala-His)4p15.2DHX9 2750 RHA DEAH (Asp-Glu-Ala-His)1q25.3DLD 2898 DLDH dihydrolipoamide dehyd 7q31.1DLG4 1742 PSD95 discs, large homolog 4 17p13.1DNAJA1 3301 DnaJ homolog subfamil 9p13-p12DNAJA2 14884 HIRIP4, DNAJ, CPRDnaJ (Hsp40) homolog, 16q12.1DNAJA3 11808 hTid-1 DnaJ (Hsp40) homolog, 16p13.3DNAJB1 3337 Hsp40 DnaJ homolog subfamil 19p13.2

CUL2

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=full_report&list_uids=9439

DNAJC1 20090 DNAJL1, ERdj1, MDnaJ (Hsp40) homolog, 10p12.31DNAJC21 134218 DNAJA5 DnaJ homolog subfamil

7802 Axonemal dynein light inDNM1 1759 dynamin 1 9q34DNM1L 1400 DRP1/CRMP1 Dihydropyrimidinase-relat4p16.1DNM2 2974 DYNII, DYN2, CMdynamin 2 [Source:HGNC19p13.2DPYSL2 3014 DRP-2, DHPRP2, Cdihydropyrimidinase-lik 8p21.2DYNC1H1 1778 DNCH1 dynein, cytoplasmic 1, he14q32.3-qter;DYNC1I2 1781 DNCI2 Cytoplasmic dynein 1 in 2q31.1ECH1 1891 Delta(3,5)-Delta(2,4)-di 19q13.1EEF1A1 1915 Elongation factor 1-alph 6q14.1EEF1D 3211 EF-1D, FLJ20897 eukaryotic translation el 8q24.3EEF1G 3213 EF1G eukaryotic translation e 11q12.3EGFR 1956 Epidermal growth factor 7p12EGR1 1958 early growth response 1 18EIF2AK2 5610 Interferon-induced, doub 2p22-p21EIF2C2 27161 AGO2 Eukaryotic translation ini8q24ENO1 3350 PPH, MBP-1 enolase 1, (alpha) [Sou 1p36.23ENO3 3354 enolase 3 (beta, muscle 17p13.2EPB41L1 2036 erythrocyte membrane prot20q11.2-q12EPS8 3420 epidermal growth factor 12p12.3ETFB 3482 electron-transfer-flavop 19q13.41EWSR1 3508 EWS Ewing sarcoma breakpoin22q12.2F8A1 8263 HAP40 Factor VIII intron 22 pro Xq28FEZ1 9638 Fasciculation and elongat11q24.2FLJ13386 80254 CEP36(?)/CEP63 centrosomal protein 63kD3q22.1-q22.2FNBP4 23360 Formin-binding protein 11p11.2FUS 2521 RNA-binding protein FU 16p11.2G3BP1 30292 HDH-VIII, G3BP GTPase activating prote 5q33.1G3BP2 30291 KIAA0660 GTPase activating prote 4q21.1GAPDH 2597 Glyceraldehyde-3-phosp 12p13GBAS 4179 NIPSNAP2 glioblastoma amplified 7p11.2GFAP 2670 glial fibrillary acidic prot 17q21GIT1 28964 ARF GTPase-activating p17p11.2GJA1 4274 CX43, ODD, ODODgap junction protein, a 6q22.31GLOD4 51031 Glyoxalase domain-conta17p13.3GNAI2 2771 GIP, GNAI2B, H_Lguanine nucleotide binding3p21.31GNAO1 4389 G-ALPHA-o guanine nucleotide bindin16q12.2GNAZ 2781 guanine nucleotide binding22q11.22GNB1 4396 guanine nucleotide bindi 1p36.33GNB2 4398 guanine nucleotide bindi 7q22.1GNB2L1 10399 HLC7, Gnb2-rs1, H guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1GPI 2821 Glucose-6-phosphate iso 19q13.1GPM6A 2823 Neuronal membrane glyc4q34GPRASP2 114928 G-protein coupled recept Xq22.1GRB2 2885 Growth factor receptor-b 17q24-q25

5p13.2DNALI1 1p35.1



GSN 4620 DKFZp313L0718 gelsolin [Source:HGNC 9q33.2GSPT1 4621 GST1, ETF3A, eRFG1 to S phase transitio 16p13.13HADHA 4801 GBP, LCEH, LCHAhydroxyacyl-CoA dehydrog2p23.3HAP1 9001 Huntingtin-associated pr 17q21.2-q21.3HIP1 3092 Huntingtin-interacting pr 7q11.23HMGB1 3146 High mobility group pr 13q12HMGB2 3148 High mobility group pr 4q31HNRNPA2B 5033 heterogeneous nuclear r 7p15.2HNRNPC 5035 hnRNPC heterogeneous nuclear r 14q11.2HSD17B10 4800 ERAB, MHBD, 17bhydroxysteroid (17-beta Xp11.22HSP90AB1 3326 RP1-302G2.1, D6S1heat shock protein 90kDa 6p12HSPA12A 19022 FLJ13874, KIAA04heat shock 70kDa prote 10q25.3HSPA2 5235 heat shock 70kDa protei 14q23.3HSPA4 3308 Heat shock 70 kDa prote 5q31.1-q31.2HSPA8 3312 Heat shock cognate 71 k 1q24.1HSPA9 5244 GRP75, PBP74, mot-heat shock 70kDa protei 5q31.2HSPD1 5261 GROEL, HSP60 heat shock 60kDa protei 2q33.1HYPK 25764 HSPC136, C15orf63huntingtin interacting pro15q15.3IKBKAP 8518 Elongator complex proteIMMT 6047 P87, P89, HMP, M inner membrane protein, 2p11.2INA 6057 NF-66 internexin neuronal inte 10q24.33ITPR1 3708 inositol 1,4,5-triphosphate3p26-p25KAT2B 8850 PCAF Histone acetyltransfera 3p24KBTBD11 29104 KIAA0711, KLHDCkelch repeat and BTB (P 8p23.3KIF5C 3800 Kinesin heavy chain iso 2q23LANCL1 6508 p40 LanC lantibiotic synthet 2q34LDHA 6535 lactate dehydrogenase A 11p15.1LDHB 6541 lactate dehydrogenase B 12p12.1LRRFIP1 6702 FLAP-1, FLIIAP1, leucine rich repeat (in F 2q37.3MAGED1 6813 NRAGE, DLXIN-1 melanoma antigen familyXp11.22MAP3K10 4294 Mitogen-activated protei 19q13.2MARCKS 6759 PKCSL, 80K-L myristoylated alanine-ri 6q21MBP 6925 myelin basic protein [S 18q23MED15 14248 TIG-1, CAG7A, Arcmediator complex subuni22q11.21MED23 9439 Mediator of RNA polymeraMED31 51003 Mediator of RNA polymera17p13.2MEF2D 4209 myocyte enhancer factor 1q12-q23MLF1 4291 Myeloid leukemia factor 3q25.1MLF2 8079 Myeloid leukemia factor 12p13MLLT4 4301 Afadin;MLLT4 6q27MOG 7197 myelin oligodendrocyte 6p22.1MTMR1 7449 myotubularin related pr Xq28MTOR 2475 FRAP, FRAP1 Mechanistic target of rapa1p36.2MYH10 7568 NMMHCB myosin, heavy chain 10, 17p13.1MYH11 7569 SMMHC, SMHC myosin, heavy chain 11, 16p13.11MYL6 7587 ESMLC, MLC3NM,myosin, light chain 6, a 12q13.2

9q31

CRSP3 6q22.33-q24.1




MYO18A 31104 KIAA0216, MysPDmyosin XVIIIA [Source 17q11.2MYO5A 7602 MYO5, GS1, MYR1myosin VA (heavy chain 15q21.2MYO5B 7603 KIAA1119 myosin VB [Source:HGN18q21.1MYO6 7605 KIAA0389 myosin VI [Source:HGNC6q14.1NAPA 8775 Alpha-soluble NSF attac 19q13.33NAPB 15751 SNAP-BETA, SNA N-ethylmaleimide-sensiti20p11.21NCKAP1 7666 Nap1, HEM2, NAP1NCK-associated protein 2q32.1NCOR1 9611 nuclear receptor corepress17p11.2NDRG2 14460 KIAA1248, SYLD NDRG family member 2 14q11.2NDUFA13 17194 CGI-39, CDA016, GNADH dehydrogenase (ub19p13.11NDUFA8 7692 PGIV, MGC793 NADH dehydrogenase (ub9q33.2NDUFA9 7693 SDR22E1, CI-39k NADH dehydrogenase (ub12p13.32NDUFB10 4716 NADH dehydrogenase (ubi2q37.3NDUFS1 7707 CI-75k NADH dehydrogenase (ub2q33.3NDUFS2 7708 CI-49 NADH dehydrogenase (ub1q23.3NDUFS3 7710 CI-30 NADH dehydrogenase (ub11p11.2NDUFV1 4723 NADH dehydrogenase (ubi11q13NDUFV2 7717 CI-24k NADH dehydrogenase (ubi18p11.22NEFL 7739 NFL, CMT1F, CMT2neurofilament, light po 8p21.2NEFM 7734 NFM, NF-M neurofilament, medium p 8p21.2NEGR1 257194 Neuronal growth regulat 1p31.1NEUROD1 4760 Neurogenic differentiat 2q32

4790 Nuclear factor NF-kappa 4q24NFYA 4800 Nuclear transcription fa 6p21.3NFYC 4802 Nuclear transcription fa 1p32NPM1 7910 B23, NPM nucleophosmin (nucleola 5q35.1NPTN 17867 SDR1, GP55, GP65, neuroplastin [Source:H 15q24.1NSF 8016 SKD2 N-ethylmaleimide-sensit 17q21.31ODF2L 57489 KIAA1229 outer dense fiber of sperm 1p22.3OPTN 10133 HIP7 Optineurin 10p13PABPC4 8557 iPABP, APP-1 poly(A) binding protein, 1p34.3PACSIN1 29993 Protein kinase C and case6p21.3PARK2 5071 E3 ubiquitin-protein lig 6q25.2-q27PCLO 13406 KIAA0559, DKFZppiccolo (presynaptic cyt 7q21.11PDHA1 8806 pyruvate dehydrogenase Xp22.12PFKL 8876 phosphofructokinase, li 21q22.3PFKM 8877 PFK-1 phosphofructokinase, mu 12q13.11PFN2 5217 Profilin-2;PFN2 3q25.1-q25.2PIAS4 51588 E3 SUMO-protein ligasePKM2 5315 Pyruvate kinase isozym 15q22PLP1 9086 proteolipid protein 1 [ Xq22.2POU3F2 5454 Brn-2 POU domain, class 3, tra 6q16PPARG 5468 Peroxisome proliferator- 3p25PPFIA3 9247 KIAA0654, LPNA3protein tyrosine phosphat19q13.33PPIB 9255 CYPB, OI9 peptidylprolyl isomerase 15q22.31PPL 5493 Periplakin;PPL 16p13.3

NFKB1

19p13.3


http://www.genenames.org/data/gdlw_columndef.html#gd_aliases

PPP1CA 9281 PP1A, PP-1A, PP1alprotein phosphatase 1, c 11q13.2PPP1R12A 7618 MBS, M130 protein phosphatase 1, r 12q21.31PRDX6 16753 AOP2, KIAA0106, 1peroxiredoxin 6 [Sourc 1q25.1PRKRA 8575 HSD14, DYT16, P protein kinase, interfero 2q31.2PRMT5 10894 SKB1Hs protein arginine methylt 14q11.2PRPF40A 55660 HYPA Pre-mRNA-processing fa2q23.3

25766 Pre-mRNA-processing fa12q5701 26S protease regulatory

PSMD8 9566 S14, Nin1p, p31, H proteasome (prosome, ma19q13.2PSPC1 20320 PSP1, FLJ10955 paraspeckle component 13q12.11PTGS2 9605 COX2 prostaglandin-endoperoxi1q31.1PTK6 5753 PTK6 Tyrosine-protein kinase 20q13.3RAB14 16524 FBP, RAB-14 RAB14, member RAS onc9q33.2RAB3A 9777 RAB3A, member RAS onc19p13.11RAD23B 5887 UV excision repair pro 9q31.2RASA1 5921 Ras GTPase-activating p 5q13.3RASD2 23551 GTP-binding protein Rh 22q13.1RBMX 9910 RNMX, hnRNP-G RNA binding motif proteXq26.3REST 5978 RE1-silencing transcripti 4q12RPL10A 10299 Csa-19, L10A ribosomal protein L10a 6p21.31RPL12 10302 L12 ribosomal protein L12 [ 9q33.3RPL15 10306 RPL10, RPLY10, RPribosomal protein L15 [ 3p24.2RPL18 10310 L18 ribosomal protein L18 [ 19q13.33RPL3 10332 L3 ribosomal protein L3 [S 22q13.1RPL6 10362 TAXREB107, L6 ribosomal protein L6 [S 12q24.13RPL7 10363 humL7-1, L7 ribosomal protein L7 [S 8q21.11RPL7A 10364 SURF3, TRUP, L7Aribosomal protein L7a [ 9q34.2RPLP0 10371 PRLP0, P0, L10E, Rribosomal protein, larg 12q24.23RPLP2 10377 P2, RPP2, MGC7140ribosomal protein, larg 11p15.5RPS10 10383 MGC88819, S10 ribosomal protein S10 [ 6p21.31RPS13 10386 S13 ribosomal protein S13 [ 11p15.1RPS16 10396 S16 ribosomal protein S16 [ 19q13.2RPS18 10401 KE3, KE-3, HKE3, ribosomal protein S18 [ 6p21.32RPS25 10413 S25 ribosomal protein S25 [ 11q23.3RPS3 10420 FLJ26283, FLJ2745ribosomal protein S3 [S 11q13.4RPS6 10429 S6 ribosomal protein S6 [S 9p22.1RPS7 10440 S7 ribosomal protein S7 [S 2p25.3RTN3 10469 NSPL2, NSPLII, A reticulon 3 [Source:HGN 11q13.1SARS 10537 SERS seryl-tRNA synthetase 1p13.3SASH1 19182 KIAA0790, dJ323MSAM and SH3 domain con6q24.3SEPT_7 989 CDC3/CDC10 septin 7 7p14.3-p14.1SETD2 29072 HYPB Histone-lysine N-methyl 3p21.31SF3A3 10767 SF3a60, SAP61, PRsplicing factor 3a, subu 1p34.3SFXN3 16087 SFX3 sideroflexin 3 [Source: 10q24.31SGK1 6446 SGK Serine/threonine-protein 6q23SH3GL3 6457 Endophilin-A3;SH3GL3 15q24

PRPF40B HYPCPSMC2 7q22.1-q22.3





SH3GLB1 51100 Endophilin-B1;SH3GLB11p22SIN3A 25942 Paired amphipathic helix 15q24.2SIRPA 9662 SHPS1, SIRP, MYD-signal-regulatory protei 20p13SLC16A1 10922 MCT, MCT1 solute carrier family 16 1p13.2SLC1A2 10940 GLT-1, EAAT2 solute carrier family 1 ( 11p13SLC25A11 10981 OGC solute carrier family 25 17p13.2SLC25A12 10982 Aralar solute carrier family 25 2q31.1SLC25A13 10983 CITRIN, ARALAR2solute carrier family 25 7q21.3SLC25A3 10989 solute carrier family 25 12q23.1SLC25A4 10990 T1 solute carrier family 25 4q35.1SLC6A1 11042 GAT1, GABATR, solute carrier family 6 3p25.3SNAP25 6616 synaptosomal-associated p20p12-p11.2SNAP91 14986 KIAA0656, AP180 synaptosomal-associated 6q14.2SNRPD3 11160 SMD3, Sm-D3 small nuclear ribonucle 22q11.23SORBS1 10580 Sorbin and SH3 domain-c10q23.3-q24.1SP1 6667 Transcription factor Sp1; 12q13.1SRGAP1 57522 SLIT-ROBO Rho GTPase ac12q14.2SRGAP2 23380 SLIT-ROBO Rho GTPase-a1q32.1SRGAP3 19744 KIAA0411, MEGAPSLIT-ROBO Rho GTPase a3p25.3SRRT 51593 ARS2 Arsenite-resistance prote 7q21SRSF3 10785 SRp20, SFRS3 serine/arginine-rich spl 6p21.31SSB 11316 LARP3, La Sjogren syndrome antige 2q31.1STIP1 11387 HOP, STI1 stress-induced-phosphop 11q13.1STX1A 6804 syntaxin 1A (brain) 7q11.23STX1B 18539 syntaxin 1B [Source:HG 16p11.2STXBP1 11444 hUNC18, MUNC18-1syntaxin binding protei 9q34.11SUB1 19985 PC4, p15, p14 SUB1 homolog (S. cerev 5p13.3SUCLA2 11448 succinate-CoA ligase, A 13q14.2SUCLG1 11449 succinate-CoA ligase, a 2p11.2SUMO1 7341 Small ubiquitin-related 2q33SUPT5H 6829 Transcription elongatio 19q13SYN1 11494 synapsin I [Source:HGN Xp11.23SYNCRIP 16918 NSAP1, GRY-RBP, synaptotagmin binding, 6q14.3SYP 11506 synaptophysin [Source: Xp11.23SYT1 11509 P65 synaptotagmin I [Sourc 12q21.2SYT2 127833 synaptotagmin II [Sour 1q32.1TAF4 6874 Transcription initiation 20q13.33TBP 6908 TATA-box-binding prote6q27TCERG1 10915 Transcription elongation 5q31TCP1 11655 D6S230E, CCT1, Cct-complex 1 [Source:HG 6q25.3TGM2 7052 Protein-glutamine gamma20q12THY1 11801 CD90 Thy-1 cell surface anti 11q23.3TJP2 11828 ZO-2, X104, ZO2 tight junction protein 2 9q21.11TLN1 7094 talin 1 9p23-p21TMOD2 11872 NTMOD tropomodulin 2 (neurona 15q21.2TNIK 30765 KIAA0551 TRAF2 and NCK interact3q26.31

TP53 7157 Cellular tumor antigen p 17p13.1TPM1 12010 tropomyosin 1 (alpha) [ 15q22.2TPM2 12011 DA1, NEM4 tropomyosin 2 (beta) [S 9p13.3TPR 7175 Nucleoprotein TPR;TPR

7189 TNF receptor-associated TRIO 7204 Triple functional domain 5p14-p15.1TRIP10 9322 Cdc42-interacting protei 19p13.3TUBB 203068 Tubulin beta chain;TUBB6p21.33

7283 Tubulin gamma-1 chainUBD 10537 FAT10 ubiquitin D 6p21.3UBE2K 3093 HIP2 Ubiquitin-conjugating 4q14UBQLN1 29979 Ubiquilin-1;UBQLN1 9q22UQCR10 30863 HSPC051, UCRC, Qubiquinol-cytochrome c 22q12.2UQCRC1 12585 D3S3191, QCR1, ubiquinol-cytochrome c r3p21.31UQCRC2 12586 QCR2, UQCR2 ubiquinol-cytochrome c r16p12.2USP9X 8239 Probable ubiquitin carb Xp11.4 UTP14A 10665 NY-CO-16 UTP14, U3 small nucleolXq26.1

6844 vesicle-associated membraVAPA 12648 hVAP-33, VAP-A VAMP (vesicle-associate18p11.22VAPB 12649 VAP-B, VAP-C, ALVAMP (vesicle-associate20q13.32VDAC1 12669 MGC111064, PORIvoltage-dependent anion 5q31.1VDAC2 7417 FLJ23841 Voltage-dependent anion-10q22VDAC3 12674 HD-VDAC3 voltage-dependent anion 8p11.21VPS35 55737 TCCCTA00141, MEvacuolar protein sorting 316q12XRCC6 2547 KU70 ATP-dependent DNA heli22q13.2-q13.3YBX1 8014 YB-1, YB1, DBPB, Y box binding protein 1 1p34.2YWHAB 7529 14-3-3 alpha/beta tyrosine 3-monooxygenase20q13.1YWHAE 7531 14-3-3E tyrosine 3-monooxygenase17p13YWHAG 7532 14-3-3GAMMA tyrosine 3-monooxygenase7q11.23

7533 14-3-3 eta tyrosine 3-monooxygenaseYWHAZ 7534 14-3-3-zeta tyrosine 3-monooxygenase8q23.1ZDHHC17 23390 HIP14 Palmitoyltransferase 12q21.2ZMYND8 23613 PRKCBP1 Protein kinase C-bindin 20q13.12ZNF91 7644 zinc finger protein 91 19p13.1-p12PIK3R1 5295 AGM7, GRB1, p85 phosphoinositide-3-kinase, regulatory subunit 1 EZRRAC1HIP14L/ ZDHHC13MeCP2CAV1UBQLN2 29978 ubiquilin-2 Symbol Gene ID Other Symbol Name Location

1q25TRAF6 11p12

TUBG1 17q21

VAMP2 17pter-p12

YWHAH 22q12.1-q13.1










Shirasaki et Shirasaki DI, Greiner ER, Al-Ramahi I, Gray M, Boontheung P, Geschwind DH, Botas J, Coppola G, Horvath S, Loo JA, Yang XW (2012) Network organization of the huntingtin proteomic interactome in mammalian brain, Neuron. 75, 41-57Ratovitski etRatovitski T, Chighladze E, Arbez N, Boronina T, Herbrich S, Cole RN, Ross CA (2012) Huntingtin protein interactions altered by polyglutamine expansion as determined by quantitative proteomic analysis, Cell Cycle. 11, 2006-2021Culver et al.Culver BP, Savas JN, Park SK, Choi JH, Zheng S, Zeitlin SO, Yates JR 3rd, Tanese N (2012) Proteomic analysis of wild-type and mutant huntingtin-associated proteins in mouse brains identifies unique interactions and involvement in protein synthesis, J Biol Chem. 287, 21599-21614

Functional implication

Loss of function Suppress Toxicity (LFST)

AKT over expression reduced toxicity and ag

LFSTLFST

LFST

Over expression enhance toxicity (OEET), L

Loss of function exnhance toxicity (LFET)Loss of function suppress motor performance iLoss of function enhance motor performance de

OEETOver expression protects toxicityKnock down reduced the mHTT toxicity

overexpression attenuates toxic effects of mutaOver expression protects mHTT aggregates in Over expression suppress toxicity in fly (OESOver expression enhance toxicity (OEET)OEET/LFSTInhibition of interaction protects toxicityLoss of function enhance motor performance de

Inhibition of CASP1 activation increases the Interaction with mutant HTT activateExpression of catalytically inactive (dominantActivated in HDExpression of catalytically inactive (dominantExpression of catalytically inactive (dominantA dominant-negative form of caspase-8 with a Not known

LFSTNot known

LFST

LFETLFETPartial depletion of CREB-binding protein re

Truncated N-terminal mutant HTT repress tranLFST

Not known

In HD, more DNG4/PSD-95 interacts with NMOEST

OEST

OEST


OEET

LFETInteraction with mutant HTT activate the enzy

MTELFETNot knownNot known

polyQ expansion inhibits EGFR signaling in Not knownActivated in HDNot known

LFST

Not knownLFETLFETNot knownNot known

LFST

LFETEnhances mutant HTT aggregates

Not knownOver expression suppress defects in motor acti

OEET, LFST

guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1OEETOEET, LFSTNot knownNot known

Not known


Polymorphic varaiations modulate age at onseOver expression of HIP1 decreased the aggreOver expression protects toxicityOver expression protects toxicity

Loss of function suppresses defetc in motor act

Over expression decrease toxicity and aggregaOver expression decrease toxicity and aggrega

Over expression decrease toxicity and aggregaNot known

OEET, LFSTSuch interaction reduce acetylase activity, tr

LFST

In HD, Freely available MAP3K10/MLK2 indu

Not knownLFSTOver expression decreased toxicity and aggreOver expression decreased toxicity and aggreLFST

rapamycin and rapamycin analog CCI-779 that

OEST


OEET, LFST

LFST

LFST

LFET

LFETNot known

Sequesteration of NFY to aggregates reducedSequesteration of NFY to aggregates reduced

LFETNot known

LFSTOver expression of PARK2 suppress mutant HT

Not knownNot knownNot known

Not knownLFST

LFET

Loss function increase toxicity in chemical model of HD


Not known

OEST, LFET

Not knownNot knownKnock down Rhes protects toxicity by mutan

Sequesteration in the cytoplasm may protect

LFST

Over expression increases the aggregates of

Not knownOEET, LFST

Not known

SGK phosphorylates huntingtin at serine 421 and that phosphorylation can protect striatal neurons against polyQ-huntingtin-induced toxicity. We find that SGK levels are increased in the brain of HD patients




Not known

Over expression reduced mHTT aggregates

LFETReduction od SP1 expression is neuroprotectiOESTLFST

LFST

OEST, LFET

Inhibition of Sumoylation enhance toxicityLFST

Over expression of TAF4/TAFII130 protects tRecruitment of TBP in cytoplasmic mutant HPolymorphic varaiations modulate age at onseLoss of function enhances the motor deficiencOver expression rescues gene expression phen

LFET

Not known


Increased aggregates

OEETNot knownNot known

Loss of function increases aggregates

Over expression reduced toxicity

OEST, LFET

LFST

Loss of function suppresses defetc in motor actInhibits repair activity, over expression prote

OEETOEET, LFSTLF did not change aggregatesNot knownLFSTMutation to Cys214 of HTT inhibits palmitoOESTOEST, LFET

phosphoinositide-3-kinase, regulatory subunit 1 Knocked down protects mutant HTT toxicityKnocked down protects mutant HTT toxicity

Knocked down of MeCP2 levels in cells expreReduced CAV1 expression in a mouse model of

Functional implication

Knock down TPR increased Nuclear mutant HTTOEET

Not known

Not known

OEST






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Reference 2 Comments/Ref3

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Functionally relevantFunctionally relevantInteraction was confirmed by IP etc

Rotovitski T et al., 2012, Cell Cycle, 11, 2006-2021NAKAP associates with HypA from human brain and copurifies with huntingtin protein in brain tissue obtained from HD patients

Eur J Neurosci. 21, 1478-1488 AKT1 expression alters in HD patients, can phosphorylate HTT, confirmed in other studies

Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57

Functionally relevantFunctionally relevant

Shirasaki DL et al., 2012, Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57Funtionally relevant

Shirasaki DL et al., 2012, Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57

Functionally relevantShirasaki DL et al., 2012, Neuron, 75, Culver BP, 2012, Culver BP, 2012, Culver BP, 2012, Culver BP, 2012, JBC, 287, 21599-21614, 287, 21599-21614, 287, 21599-21614, 287, 21599-21614

unctionally relevantShirasaki DL et al., 2012, Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57Shirasaki DL et al., 2012, Shirasaki DLCulver BP, 2012, Culver BP, 2012, JBC, 287, 21599-21614, 287, 21599-21614Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57

Functionally relevantSroka K et al. 2009,J Neurochem., 111Protects clearing mHTT aggregatesTourette C et al., 2014, Culver BP, 2012, JBC, 287, 21599-21614, In pressShirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57

The protein colocalized with mHTT in mice, confirmed co-IPMetzger S et al., 2010, Hum Genet. 12Autopghay related ATG7 polymorphism alters Agae at onset

Functionally relevantInteract equally, over expression supress toxicityFunctionally relevant

Dudek NL, 2010, Brain Pathol. 20, 17 Functionally relevantShirasaki DL et al., 2012, Neuron, 75, Functionally relevantShirasaki DL et al., 2012, Neuron, 75, Functionally relevant



Functionally relevantIP characterized




Culver BP, 2012, JBC, 287, 21599-21614, 287, 21599-21614Shirasaki DL et al., 2012, Neuron, 75, Culver BP, 2012, Culver BP, 2012, JBC, 287, 21599-21614, 287, 21599-21614Shirasaki DL et al., 2012, Neuron, 75, Culver BP, 2012, Culver BP, 2012, JBC, 287, 21599-21614, 287, 21599-21614Shirasaki DL et al., 2012, Neuron, 75, Culver BP, 2012, Culver BP, 2012, JBC, 287, 21599-21614, 287, 21599-21614

Functionally relevantFunctionally relevantcaspase-2 cleaves Htt selectively at amino acid 552

Zhang Y, et al., 2006, EMBO J. 25, 5 the huntingtin antibody immunoprecipitaKim YJ,et al., 2001,Proc Natl Acad Sci U S A. 98, 12784-12789. Graham RK et al., 2010, J Neurosci.,3 proteolysis of htt at the 586 aa caspase-6Hermel E et al.,2004,Cell Death and DiExpression of catalytically inactive (dominant-negative) forms caspase-7 reduced the cell death of YAC72 primary striatal cellsU M, Miyashita T et al., 2001, Cell DeA dominant-negative form of caspase-8 with a mutation at the catalytic cysteine residue inhibited polyglutamine-mediated nuclear apoptotic phenotype

In vitro interaction was confirmed, Expressed in brain, not localized specifically with Human HD aggregates (Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57

Confirmed by IP, Interacts with HYPK (mint)Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57

Functionally relevantShirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57

Culver BP, 2012, JBC, 287, 21599-21614, 287, 21599-21614Culver BP, 2012, JBC, 287, 21599-21614, 287, 21599-21614Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57


Steffan et al., Nature 413, 739-743 51QP interacts primarily with the region of CBP containing the acetyltransferase and CH3 domainsCulver BP, 2012, Culver BP, 2012, JBC, 287, 21599-21614, 287, 21599-21614

Kegel et al., 2002 HD cells, the protein interacts with endogenous full length HTT, repress transcription Interacts with TRIP10, a confirmed HTT interactor, functionally relevantFunctionally relevant

Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57Rotovitski T et al., 2012, Cell Cycle, 11, 2006-2021

Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57

Sun et al., 2001 Interacts with wild type HTT, not with mHTT, associated with NMDA Culver BP, 2012, JBC, 287, 21599-21Colocalized with aggregates, IP, functionally relevantShirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57

Lotz GP et al.,2010 J Biol Chem., 285 Hsp40 (DNAJB1) dynamically target specific subsets of soluble oligomers of mHTTin a classic ATP-dependent reaction cycle

Jones AL, 1999, Phil Trans R Soc Lond B, 354, 1021-








Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57Functionally relevantObserved by Kaltenbach et al., 2007 alsoFunctionally relevant

Song W, 2011, Nature Medicine, 17, 3IP confirmed, functionally relevant

Functionally relevant

Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57Liu et al., 1997 In vivo (cell) interaction was confirmed by IP

Functionally related , affected in HD mouseBinds preferentially to mhtt transcript, Functionally relevant, activated in HD brainCo-purification, Mass spectrometry, IP

Onofri F et al., Culver BP, 2012, JBCShirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57

Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57IP, interacts with full length bupt not with the N-terminal HTT, Factor VIII intron 22 proteinObserved by Kaltenbach et al. also, LFETFunctionally relevant

Faber et al., 1998, HMG, 7, 1463-1474Earlier observed by Faber et al 1998 directly bind to truncated N-terminal huntingtin (tNhtt) aggregates but could not bind to monomer

Culver BP, 2012, Culver BP, 2012, JBC, 287, 21599-21614, 287, 21599-21614Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57Burke et al., 1996 In vitro (cell extracts) bindsShirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57

Funtionally relevantConfirmed binding and functionally relevant

Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57IP confirmed

Shirasaki DL et al., 2012, Neuron, 75, Functionally relevantFunctionally relevant

Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57Shirasaki DL et al., 2012, Neuron, 75, Culver BP, 2012, Culver BP, 2012, JBC, 287, 21599-21614, 287, 21599-21614

Culver BP, 2012, Culver BP, 2012, JBC, 287, 21599-21614, 287, 21599-21614Funtionally relevantFunctionally relevant

Goehler et al. 2004 GASP2 form a complex in cotransfected mammalian cells, IP, also observed in Y2HLiu et al., 1997 Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57, IP


Functionally relevantConfirmed, IPIsolated from aggregates in mice model, IP (unpublished observation by us), functionally related



Interacts with SYN1(string) that interacts with GRB2








In vitro binding, immunoprecipitation, and coexpression studies confirm the interaction of hHAP with huntingtin. Several studiesReconstituted Complex, Affinity Capture-Western, confirmed in various studies

Qi et al., 2007 Colocalization in cells, IPQi et al., 2007 Colocalization, IPShirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57

Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57Functionally relevant


in numeroous studies, HSP70 localized with mHTT aggregates, functionally relevantin numeroous studies, HSC70 localized with mHTT aggregates, functionally relevant


Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57Tang TS et al., 2003 Shirasaki DL et a Independent studies, in vitro complex, HAP1, ITPR, HTT complex, mHTT dependent , suppress toxicity

expanded repeat domain of Htt interacts with both CBP and P/CAF primarily through the acetyltransferase and neighbouring domainsShirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57


Rotovitski T et al., 2012, Cell Cycle, 11, 2006-2021Culver BP, 2012, Culver BP, 2012, JBC, 287, 21599-21614, 287, 21599-21614Liu et al., 2000 IP, In cell model MAP3K10 implicated in the toxicity by the mutant HTT Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57

Confirmed by IPFunctionally relevant

IP, unpublished observation by us, functinally relevantFunctionally relevant

Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57Confirmed by IP


Kaltenbach LS et al., 2007, PLoS Genet. 3, e82Li et al. 1995

IP, reduced aggreagtes in cell modelIP, confirmed

Steffan et al., 2001


Kaltenbach LS et al., 2007, PLoS Genet. 3, e82Functionally relevant


IP, unpublished observation by US, functtionally relevant









Shirasaki DL et al., 2012, Neuron, 75, Culver BP, 2012, Culver BP, 2012, JBC, 287, 21599-21614, 287, 21599-21614Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57

Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57






IP confirmed

Aggregate specific interactions, not with soluble proteins, functionally relevantAggregate specific interactions, not with soluble proteins, functionally relevant


Shirasaki DL et al., 2012, Neuron, 75, 41-57

Hattula and Peränen, 2000, Curr Biol. HTT interacts with Rab8 via OPTN/HIP7Culver BP, 2012, Culver BP, 2012, JBC, 287, 21599-21614, 287, 21599-21614

PARKIN functionally related to HDShirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57

Confirmed by IPConfirmed by IPConfirmed by IP

Shirasaki DL et al., 2012, Neuron, 75, Culver BP, 2012, Culver BP, 2012, JBC, 287, 21599-21614, 287, 21599-21614Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57


Functionally relevantKaltenbach LS et al., 2007, PLoS Genet. 3, e82







Takano et al., 2002 NF-kB associates with huntingtin (IP) after dissociation from its inhibitory protein, IkB, when NF-kB is available for translocation to the nucleus.Kaltenbach et al., 2007



IP, associated with mutant HTT, alters PACSIN1 distribution in HD patientsRubio I et al., 2009, Brain Research, 1281, 91-100











Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57Goehler H., 2004, Gao YG et al., 2006,Confirmed in several studies (MINT)

Faber et al., 1998Culver BP, 2012, Culver BP, 2012, JBC, 287, 21599-21614, 287, 21599-21614


Culver BP, 2012, JBC, 287, 21599-21Confirmed by IP

Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57Immunoprecipitation, HD brain extract etc, several studies confirmed

Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57Culver BP, 2012, JBC, 287, 21599-21614, 287, 21599-21614Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57Culver BP, 2012, JBC, 287, 21599-21614, 287, 21599-21614Culver BP, 2012, JBC, 287, 21599-21614, 287, 21599-21614Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57Culver BP, 2012, JBC, 287, 21599-21614, 287, 21599-21614Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57



Confirmed by IP, Coimmunoprecipitations and immunofluorescence, HD brain extracts


Kaltenbach LS et al., 2007, PLoS Genet. 3, e82Recruted to mutant HTT aggregates

Liu et al., 1997 Confirmed, IP, Co-localization


Confirmed by IP, Participate in Histone methylation

Kaltenbach LS et al., 2007, PLoS Genet. 3, e82Functinally relevant, SGK phosphorylates huntingtin at serine 421 and that phosphorylation can protect striatal Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57s against polyQ-huntingtin-induced toxicity. We find that SGK levels are increased in the brain of HD patients







Confirmed by IP




Smith R,2007, J Neurochem.,103,115-Loss of SNAP-25 in brains of HD pateintsShirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57

Functionally relevantLi SH et al.,2002, Mol Cell Biol. 22, soluble mutant huntingtin inhibits Sp1 binding to DNA in postmortem brain tissues of both presymptomatic and affected HD patients


Functionally relevantShirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57

Functionally relevantShirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57

Funtionally relevant, colocalize in cells, k mutation reduce sumoylation, functionally related to HD (fly)Functionally relevant


Confirmed, over expression enhance toxicity Huang CC et al.,1998, Somat Cell MolTBP dislocated to the cytoplasm and colocalized with the mutant HTT aggregates.In vitro FRET assay, TBP interacts with TBP faster than that of the wild type HTT

IP,expression increased in HD brain, variation explains age at onsetShirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57McConoughey SJ et al., 2011, EMBO MLocalized and IP with truncated HTT (N-terminal)

Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57Functionally relevant


Boutell et al., 1999 mSin3A immunoreactivity occurred in a subset of huntingtin positive intranuclear inclusions in cytoplasm of HD brainKaltenbach LS et al., 2007, PLoS Genet. 3, e82




Functionall relevant



Kaltenbach LS et al., 2007, PLoS Genet. 3, e82Kaltenbach LS et al., 2007, PLoS Genet. 3, e82Kaltenbach LS et al., 2007, PLoS Genet. 3, e82Dunah at al., 2002






p53 localized in mHTT inclusions and to interacts with p53 in vitro and in cell culture



IP confirmedHD lymphoblast cell, IP, histochemistryFunctionally relevant

Faber et al., 1998, HMG, 7, 1463-1474Wang H, 2006, Hum Mol Genet., 15, 1Functionally relevantShirasaki DL et al., 2012, Neuron, 75, 41-57

Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57Shirasaki DL et al., 2012, Neuron, 75, Culver BP, 2012, JBC, 287, 21599-21614, 287, 21599-21614

FunctionallyKaltenbach et al., 2007Functionally relevantPull down in vitro, confirmedCulver et al., 2012Confirmed by IP, functionally relevant

Shirasaki DL et al., 2012, Neuron, 75, Functionally relevantShirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57Shirasaki DL et al., 2012, Neuron, 75, confirmed by IPOmi et al, 2008 knock down YWHAZ exclusively abolished the formation of large mutant HTT inclusion bodiesYanai A et al., 2006, Nat. Neurosci.,9


Tourette C et al., 2014, J Biol Chem. 289, 6709-6726Tourette C et al., 2014, J Biol Chem. 289, 6709-6726Tourette C et al., 2014, J Biol Chem. 289, 6709-6726Sutton LM et al., 2013, Hum Mol Genet. 22, 452-465

Reference 2 Comments/Ref3

Steffan JS et al., Proc Natl Acad Sci U S A. 2000 97, 6763-8Kaltenbach LS et al., 2007, PLoS Genet. 3, e82

Functional relevant, Tpr has a role in the nuclear export of N-terminal htt and that polyQ expansion reduces this nuclear export to cause the nuclear accumulation of htt.Functionally relevant

Holbert et al., 2003 CIP4 immunoreactivity and ubiquitin-positive inclusions colocalized within the HD tissue specimens

In vitro, IP binding


Funtionally relevantKaltenbach LS et al., 2007, PLoS Genet. 3, e82


Enokido Y et al., 2010, J Cell Biol., 189, 425-443

Omi et al, 2008, Neuroscience Letters,431, 45-50

Functionally relevant, partial co-localization with htt in the striatum












Culver BP, 2012, Culver BP, 2012, Culver BP, 2012, JBC, 287, 21599-21614, 287, 21599-21614, 287, 21599-21614Shirasaki DL et al., 2012, Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57, 75, 41-57

NAKAP associates with HypA from human brain and copurifies with huntingtin protein in brain tissue obtained from HD patientsAKT1 expression alters in HD patients, can phosphorylate HTT, confirmed in other studies

Culver BP, 2012, Culver BP, 2012, Culver BP, 2012, Culver BP, 2012, JBC, 287, 21599-21614, 287, 21599-21614, 287, 21599-21614, 287, 21599-21614

Culver BP, 2012, Culver BP, 2012, JBC, 287, 21599-21614, 287, 21599-21614

The protein colocalized with mHTT in mice, confirmed co-IPAutopghay related ATG7 polymorphism alters Agae at onset

Culver BP, 2012, Culver BP, 2012, JBC, 287, 21599-21614, 287, 21599-21614Culver BP, 2012, Culver BP, 2012, JBC, 287, 21599-21614, 287, 21599-21614Culver BP, 2012, Culver BP, 2012, JBC, 287, 21599-21614, 287, 21599-21614

Kim YJ,et al., 2001,Proc Natl Acad Sci U S A. 98, 12784-12789.

Expression of catalytically inactive (dominant-negative) forms caspase-7 reduced the cell death of YAC72 primary striatal cellsA dominant-negative form of caspase-8 with a mutation at the catalytic cysteine residue inhibited polyglutamine-mediated nuclear apoptotic phenotypeIn vitro interaction was confirmed, Expressed in brain, not localized specifically with Human HD aggregates (

51QP interacts primarily with the region of CBP containing the acetyltransferase and CH3 domainsCulver BP, 2012, Culver BP, 2012, JBC, 287, 21599-21614, 287, 21599-21614HD cells, the protein interacts with endogenous full length HTT, repress transcription Interacts with TRIP10, a confirmed HTT interactor, functionally relevant

Interacts with wild type HTT, not with mHTT, associated with NMDA

Hsp40 (DNAJB1) dynamically target specific subsets of soluble oligomers of mHTTin a classic ATP-dependent reaction cycle

Binds preferentially to mhtt transcript, Functionally relevant, activated in HD brain

IP, interacts with full length bupt not with the N-terminal HTT, Factor VIII intron 22 protein

directly bind to truncated N-terminal huntingtin (tNhtt) aggregates but could not bind to monomer


GASP2 form a complex in cotransfected mammalian cells, IP, also observed in Y2H

Isolated from aggregates in mice model, IP (unpublished observation by us), functionally related


In vitro binding, immunoprecipitation, and coexpression studies confirm the interaction of hHAP with huntingtin. Several studiesReconstituted Complex, Affinity Capture-Western, confirmed in various studies

in numeroous studies, HSP70 localized with mHTT aggregates, functionally relevantin numeroous studies, HSC70 localized with mHTT aggregates, functionally relevant

Independent studies, in vitro complex, HAP1, ITPR, HTT complex, mHTT dependent , suppress toxicityexpanded repeat domain of Htt interacts with both CBP and P/CAF primarily through the acetyltransferase and neighbouring domains

IP, In cell model MAP3K10 implicated in the toxicity by the mutant HTT


Aggregate specific interactions, not with soluble proteins, functionally relevantAggregate specific interactions, not with soluble proteins, functionally relevant



Kaltenbach et al., 2007

IP, associated with mutant HTT, alters PACSIN1 distribution in HD patients



Immunoprecipitation, HD brain extract etc, several studies confirmed

Confirmed by IP, Coimmunoprecipitations and immunofluorescence, HD brain extractsFunctinally relevant, SGK phosphorylates huntingtin at serine 421 and that phosphorylation can protect striatal Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57s against polyQ-huntingtin-induced toxicity. We find that SGK levels are increased in the brain of HD patients

soluble mutant huntingtin inhibits Sp1 binding to DNA in postmortem brain tissues of both presymptomatic and affected HD patients

Funtionally relevant, colocalize in cells, k mutation reduce sumoylation, functionally related to HD (fly)

TBP dislocated to the cytoplasm and colocalized with the mutant HTT aggregates.In vitro FRET assay, TBP interacts with TBP faster than that of the wild type HTT IP,expression increased in HD brain, variation explains age at onset

mSin3A immunoreactivity occurred in a subset of huntingtin positive intranuclear inclusions in cytoplasm of HD brain


p53 localized in mHTT inclusions and to interacts with p53 in vitro and in cell culture

Culver BP, 2012, JBC, 287, 21599-21614, 287, 21599-21614

knock down YWHAZ exclusively abolished the formation of large mutant HTT inclusion bodies

Functional relevant, Tpr has a role in the nuclear export of N-terminal htt and that polyQ expansion reduces this nuclear export to cause the nuclear accumulation of htt.

CIP4 immunoreactivity and ubiquitin-positive inclusions colocalized within the HD tissue specimens

Functionally relevant, partial co-localization with htt in the striatum




Functinally relevant, SGK phosphorylates huntingtin at serine 421 and that phosphorylation can protect striatal Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57s against polyQ-huntingtin-induced toxicity. We find that SGK levels are increased in the brain of HD patients

TBP dislocated to the cytoplasm and colocalized with the mutant HTT aggregates.In vitro FRET assay, TBP interacts with TBP faster than that of the wild type HTT

Functional relevant, Tpr has a role in the nuclear export of N-terminal htt and that polyQ expansion reduces this nuclear export to cause the nuclear accumulation of htt.


Functinally relevant, SGK phosphorylates huntingtin at serine 421 and that phosphorylation can protect striatal Shirasaki DL et al., 2012, Neuron, 75, 41-57, 75, 41-57s against polyQ-huntingtin-induced toxicity. We find that SGK levels are increased in the brain of HD patients

Supplementary Table S2 Genes identified to alter HD pathogenesis in Genome wide knock down screen AssociatedGeneNameOthers Description EntrezGene ID Chromosome AACS AACS acetoacetyl-CoA synt 65985 12AADACL1 AADACL1 /NCEH1 neutral cholesterol es57552 3AASDHPPT AASDHPPT aminoadipate-semial 60496 11ABHD4 ABHD4 abhydrolase domain c63874 14ACACA ACACA acetyl-CoA carboxyla 31 17ACADM ACADM acyl-CoA dehydrogena34 1ACP2 ACP2 acid phosphatase 2, 53 11ACPP ACPP acid phosphatase, pr 55 3ACY1 ACY1 aminoacylase 1 [Sour95 3ADAM21 ADAM21 ADAM metallopeptida8747 14ADAM9 ADAM9 ADAM metallopeptida8754 8ADAMTS6 ADAMTS6 ADAM metallopeptidas11174 5ADD1 ADD1 adducin 1 (alpha) [S 118 4AFG3L2 AFG3L2 AFG3-like AAA ATPase10939 18AGPS alkylglycerone phosphate synthase 2AIP AIP aryl hydrocarbon rec 9049 11ALDOA ALDOA aldolase A, fructose 226 16ALG2 ALG2 ALG2, alpha-1,3/1,6- 85365 9ALG6 ALG6 ALG6, alpha-1,3-gluc 29929 1ALYREF THOC4 Aly/REF export factor 17AP1M1 AP1M1 adaptor-related prot 8907 19AP2S1 AP2S1 adaptor-related prot 1175 19APM2/ADIRF APM2/ADIRF adipogenesis regulato10974 10APOBEC3F APOBEC3F apolipoprotein B mRN200316 22APP APP amyloid beta (A4) pr 351 21APRT APRT adenine phosphoribos353 16APTX APTX aprataxin [Source:HG54840 9AQP3 AQP3 aquaporin 3 (Gill bl 360 9AQP8 AQP8 aquaporin 8 [Source: 343 16AR AR androgen receptor [ 367 XARD1A NAA10 N(alpha)-acetyltransfe8260 XARF4 ARF4 ADP-ribosylation fac 378 3ARHGAP1 ARHGAP1 Rho GTPase activatin 392 11ARHGAP18 ARHGAP18 Rho GTPase activatin 93663 6ARHGAP33 ARHGAP33 Rho GTPase activatin 115703 19ARHGAP35 GRLF1 Rho GTPase activating protein 35 19ARHGEF26 ARHGEF26 Rho guanine nucleoti 26084 3ARL2 ARL2 ADP-ribosylation fact 402 11ARNTL ARNTL aryl hydrocarbon rece406 11ARPC1A ARPC1A actin related protei 10552 7ARRDC2 ARRDC2 arrestin domain cont 27106 19ASCL4 ASCL4 achaete-scute family 121549 12ASF1B ASF1B anti-silencing funct 55723 19ASH2L ASH2L ash2 (absent, small, 9070 8ASNS ASNS asparagine synthetas 440 7

ATAD2B ATAD2B ATPase family, AAA d54454 2ATOX1 ATOX1 antioxidant 1 copper 475 5ATP5A1 ATP5A1 ATP synthase, H+ tran498 18ATP5C1 ATP5C1 ATP synthase, H+ tra 509 10ATP5F1 ATP5F1 ATP synthase, H+ tra 515 1ATP6V0A1 ATP6V0A1 ATPase, H+ transport 535 17ATP6V1E2 ATP6V1E2 ATPase, H+ transport 90423 2ATP7a ATP7A ATPase, Cu++ transpo538 XATXN2 ATXN2 ataxin 2 [Source:HGN6311 12AVL9 AVL9 AVL9 homolog (S. cer23080 7BACE1 BACE1 beta-site APP-cleavi 23621 11BACE2 BACE2 beta-site APP-cleavi 25825 21BAT1 DDX39B DEAD (Asp-Glu-Ala-As7919 6BCKDHA BCKDHA branched chain keto 593 19BEST3 BEST3 bestrophin 3 [Source 144453 12BPHL BPHL biphenyl hydrolase-li 670 6BTBD10 BTBD10 BTB (POZ) domain con84280 11BTG1 BTG1 B-cell translocation 694 12BUB1 BUB1 BUB1 mitotic checkpo699 2BUB3 BUB3 BUB3 mitotic checkpo9184 10BXDC2 BRIX1 BRX1, biogenesis of ribosomes, homolog (S.5C19orf29 CACTIN cactin, spliceosome C complex subunit 19C20orf3/CASS4 CASS4 Cas scaffolding protein family member 4 20C20orf43 RTFDC1 replication termination factor 2 domain con20C3orf58 DIA1 chromosome 3 open reading frame 58 3C7orf26 C7orf26 chromosome 7 open r79034 7C9ORF3 C9orf3 chromosome 9 open r84909 9CACNA1E CACNA1E calcium channel, vol 777 1CALU CALU calumenin [Source:H 813 7CAMK1D CAMK1D calcium/calmodulin-d57118 10CAPN2 CAPN2 calpain 2, (m/II) lar 824 1CAPZB CAPZB capping protein (acti 832 1CASK CASK calcium/calmodulin-d8573 XCASP3 CASP3 caspase 3, apoptosis 836 4CBFA2T2 CBFA2T2 core-binding factor, 9139 20CCDC149 CCDC149 coiled-coil domain c 91050 4CCND1 CCND1 cyclin D1 [Source:HG 595 11CCNE1 CCNE1 cyclin E1 [Source:HG 898 19CCNH CCNH cyclin H [Source:HGN902 5CCNI CCNI cyclin I [Source:HGN 10983 4CCT4 CCT4 chaperonin containin10575 2CCT5 CCT5 chaperonin containin22948 5CCT6B CCT6B chaperonin containin10693 17CCT7 CCT7 chaperonin containin10574 2CD4 CD4 CD4 molecule [Sourc 920 12CDC5L CDC5L cell division cycle 5 988 6CDK5RAP1 CDK5RAP1 CDK5 regulatory subu51654 20

CDK7 CDK7 cyclin-dependent kin 1022 5CELF1 CUGBP1 CUG triplet repeat, RNA-binding protein 1, 11CHCHD4 CHCHD4 coiled-coil-helix-coi 131474 3CHKB CHKB choline kinase beta 1120 22CHTF18 CHTF18 CTF18, chromosome tr63922 16CKB CKB creatine kinase, bra 1152 14CLDN12 CLDN12 claudin 12 [Source:H 9069 7CMPK1 CMPK1 cytidine monophospha51727 1CNGA3 CNGA3 cyclic nucleotide ga 1261 2CNOT7 CNOT7 CCR4-NOT transcripti 29883 8COG1 COG1 component of oligome9382 17COL15A1 COL15A1 collagen, type XV, a 1306 9COL4A5 COL4A5 collagen, type IV, al 1287 XCOLEC11 COLEC11 collectin sub-family 78989 2COLQ COLQ collagen-like tail su 8292 3COPE COPE coatomer protein com11316 19COPS5 COPS5 COP9 signalosome sub10987 8CPA1 CPA1 carboxypeptidase A1 1357 7CPA2 CPA2 carboxypeptidase A2 1358 7CPB1 CPB1 carboxypeptidase B1 1360 3CPO CPO carboxypeptidase O 130749 2CPS1 CPS1 carbamoyl-phosphate 1373 2CPSF2 CPSF2 cleavage and polyaden53981 14CPSF3 CPSF3 cleavage and polyaden51692 2CPSF3L CPSF3L cleavage and polyaden54973 1CPT2 CPT2 carnitine palmitoylt 1376 1CREBL2 CREBL2 cAMP responsive elem1389 12CRIP1 CRIP1 cysteine-rich protein 1396 14CRISP3 CRISP3 cysteine-rich secreto 10321 6CRNKL1 CRNKL1 crooked neck pre-mRN51340 20CS CS citrate synthase [So 1431 12CSNK2A1 CSNK2A1 casein kinase 2, alp 1457 20CSNK2B CSNK2B casein kinase 2, bet 1460 6CTH CTH cystathionase (cysta 1491 1CTNNBL1 CTNNBL1 catenin, beta like 1 56259 20CTNS CTNS cystinosin, lysosomal 1497 17CTSD CTSD cathepsin D [Source: 1509 11CUL1 CUL1 cullin 1 [Source:HGN 8454 7CUL2 CUL2 cullin 2 [Source:HGN 8453 10CYLD CYLD cylindromatosis (tur 1540 16CYP2C8 CYP2C8 cytochrome P450, fam1558 10CYP3A5 CYP3A5 cytochrome P450, fam1577 7DAB2 DAB2 Dab, mitogen-respons1601 5DAXX DAXX death-domain associa1616 6DDX24 DDX24 DEAD (Asp-Glu-Ala-As57062 14DDX5 DDX5 DEAD (Asp-Glu-Ala-As100616408 17DGCR14 DGCR14 DiGeorge syndrome cr8220 22

DHX8 DHX8 DEAH (Asp-Glu-Ala-Hi1659 17DIABLO DIABLO diablo, IAP-binding 56616 12DIAPH1 DIAPH1 diaphanous-related f 1729 5DLX4 DLX4 distal-less homeobox 1748 17DMTF1 DMTF1 cyclin D binding myb-9988 7DNAJA1 DNAJA1 DnaJ (Hsp40) homolog3301 9DNAJB1 HSP40 DnaJ (Hsp40) homolog, subfamily B, memb19DNAJB12 DNAJB12 DnaJ (Hsp40) homolog54788 10DNAJB4 DNAJB4 DnaJ (Hsp40) homolog11080 1DOPEY1 DOPEY1 dopey family member23033 6DPEP3 DPEP3 dipeptidase 3 [Sourc 64180 16DR1 DR1 down-regulator of tra1810 1DUSP8 DUSP8 dual specificity pho 1850 11DYNLT1 DYNLT1 dynein, light chain, 6993 6ECHDC3 ECHDC3 enoyl CoA hydratase 79746 10EDF1 EDF1 endothelial different 8721 9EEF2 EEF2 eukaryotic translatio 1938 19EFTUD2 EFTUD2 elongation factor Tu 9343 17EIF2AK2 PRKR eukaryotic translation initiation factor 2-al 2EIF2AK3 EIF2AK3 eukaryotic translatio 9451 2EIF2B1 EIF2B1 eukaryotic translatio 1967 12EIF2S2 EIF2S2 eukaryotic translatio 8894 20EIF2S3 EIF2S3 eukaryotic translatio 1968 XEIF3A EIF3A eukaryotic translatio 8661 10EIF3B EIF3S9 eukaryotic translation initiation factor 3, 7EIF3E EIF3E eukaryotic translatio 3646 8EIF3l EIF3S2 eukaryotic translation initiation factor 3, 1EIF4G3 EIF4G3 eukaryotic translatio 8672 1EIF5 EIF5 eukaryotic translatio 1983 14ENPEP ENPEP glutamyl aminopeptid2028 4ENTPD1 ENTPD1 ectonucleoside triph 953 10ENTPD2 ENTPD2 ectonucleoside triph 954 9ENTPD3 ENTPD3 ectonucleoside triph 956 3ENTPD4 ENTPD4 ectonucleoside triph 9583 8ENTPD5 ENTPD5 ectonucleoside triph 957 14ENTPD6 ENTPD6 ectonucleoside triph 955 20ENTPD7 ENTPD7 ectonucleoside triph 57089 10ENTPD8 ENTPD8 ectonucleoside triph 377841 9EPS8L1 EPS8L1 EPS8-like 1 [Source: 54869 19ERCC3 ERCC3 excision repair cros 2071 2ETF1 ETF1 eukaryotic translatio 2107 5EXOC4 EXOC4 exocyst complex com60412 7FABP1 FABP1 fatty acid binding pr 2168 2FABP3 FABP3 fatty acid binding pr 2170 1FABP5 FABP5 fatty acid binding pr 2171 8FADS1 FADS1 fatty acid desaturas 3992 11FAN1 FAN1 FANCD2/FANCI-associ22909 15

FARSB FARSB phenylalanyl-tRNA sy10056 2FASN FASN fatty acid synthase 2194 17FBLN1 FBLN1 fibulin 1 [Source:HG 2192 22FCHO2 FCHO2 FCH domain only 2 [ 115548 5FEN1 FEN1 flap structure-specif 2237 11FHOD3 FHOD3 formin homology 2 do80206 18FKBP2 FKBP2 FK506 binding protei 2286 11FNTA FNTA farnesyltransferase, 2339 8FOXD4 FOXD4 forkhead box D4 [So 2298 9FPR2 FPR2 formyl peptide recep 2358 19FPR3 FPR3 formyl peptide recep 2359 19FRAP1 MTOR mechanistic target of rapamycin (serine/th1FTH1 FTH1 ferritin, heavy polyp 2495 11GABARAP GABARAP GABA(A) receptor-ass11337 17GALNT2 GALNT2 UDP-N-acetyl-alpha-D2590 1GAPDH GAPDH glyceraldehyde-3-ph 2597 12GAST GAS gastrin 17GCNT1 GCNT1 glucosaminyl (N-acety2650 9GDF10 GDF10 growth differentiati 2662 10GDF11 GDF11 growth differentiation factor 11 12GFPT1 GFPT1 glutamine--fructose- 2673 2GLOD4 GLOD4 glyoxalase domain co51031 17GLRA1 GLRA1 glycine receptor, al 2741 5GLRA2 GLRA2 glycine receptor, al 2742 XGMDS GMDS GDP-mannose 4,6-deh2762 6GNG13 GNG13 guanine nucleotide b 51764 16GOT1 GOT1 glutamic-oxaloacetic 2805 10GPI GPI glucose-6-phosphate 2821 19GPRC5D GPRC5D G protein-coupled re 55507 12GRIN1 GRIN1 glutamate receptor, 2902 9GRIN2A GRIN2A glutamate receptor, 2903 16GRIN2B GRIN2B glutamate receptor, 2904 12GSK3B GSK3B glycogen synthase ki 2932 3GSS GSS glutathione syntheta 2937 20GSTP1 GSTP1 glutathione S-transfe 2950 11GTF3C5 GTF3C5 general transcription 9328 9GUF1 GUF1 GUF1 GTPase homolog 60558 4HAMP HAMP hepcidin antimicrobi 57817 19HCAR1 GPR81 hydroxycarboxylic acid receptor 1 12HCN1 HCN1 hyperpolarization act348980 5HDAC2 HDAC2 histone deacetylase 3066 6HDLBP HDLBP high density lipoprot 3069 2HEXB HEXB hexosaminidase B (be3074 5HGD HGD homogentisate 1,2-d 3081 3HIF1A HIF1A hypoxia inducible fact3091 14HIST1H1D HIST1H1D histone cluster 1, H 3007 6HIST1H2AC HIST1H2AC histone cluster 1, H 8334 6

HIST1H2BL HIST1H2BL histone cluster 1, H 8340 6HIST1H3H HIST1H3H histone cluster 1, H 8968 6HIST2H4B HIST2H4B histone cluster 2, H 554313 1HMGCR HMGCR 3-hydroxy-3-methylgl3156 5HMGCS2 HMGCS2 3-hydroxy-3-methylgl3158 1HRH1 HRH1 histamine receptor H 3269 3HRH2 HRH2 histamine receptor H 3274 5HSD17B14 HSD17B14 hydroxysteroid (17-b 51171 19HSD17B2 HSD17B2 hydroxysteroid (17-b 3294 16HSDL2 HSDL2 hydroxysteroid dehyd84263 9HSF1 HSF1 heat shock transcript 3297 8HSP90AA1 HSP90AA1 heat shock protein 9 3320 14HSPA4 HSPA4 heat shock 70kDa pro3308 5HSPA5 HSPA5 heat shock 70kDa pro3309 9HSPA9 HSPA9 heat shock 70kDa pro3313 5HTR1F HTR1F 5-hydroxytryptamine 3355 3HYI HYI hydroxypyruvate isom81888 1ICK ICK intestinal cell (MAK- 22858 6IL18BP IL18BP interleukin 18 bindi 10068 11IL18R1 IL18R1 interleukin 18 recep 8809 2IL19 IL19 interleukin 19 [Sour 29949 1IL1F6 IL36A interleukin 36, alpha 27179 2IL1RAP IL1RAP interleukin 1 recepto 3556 3ILK ILK integrin-linked kina 3611 11INTS2 INTS2 integrator complex s 57508 17INTS4 INTS4 integrator complex s 92105 11INTS7 INTS7 integrator complex s 25896 1INTS8 INTS8 integrator complex s 55656 8INTS9 RC74 integrator complex su55756 8IPO5 IPO5 importin 5 [Source:H 3843 13IPPK IPPK inositol 1,3,4,5,6-p 64768 9ISY1 ISY1 ISY1 splicing factor 57461 3JUND JUND jun D proto-oncogen 3727 19KAL1 KAL1 Kallmann syndrome 13730 XKAT7 KAT7 K(lysine) acetyltrans 11143 17KCNC1 KCNC1 potassium voltage-ga3746 11KCNRG KCNRG potassium channel re283518 13KCTD3 KCTD3 potassium channel te51133 1KIAA1143 KIAA1143 KIAA1143 [Source:HG57456 3KIF11 KIF11 kinesin family membe3832 10KIF13A KIF13A kinesin family memb 63971 6KIF21B KIF21B kinesin family membe23046 1KIF23 KIF23 kinesin family membe9493 15KIFC1 KIFC1 kinesin family membe3833 6KLF9 KLF9 Kruppel-like factor 687 9KMT2E MLL5 lysine (K)-specific methyltransferase 2E 7LAMTOR3 MP1 late endosomal/lysosomal adaptor, MAPK 4

LDB3 LDB3 LIM domain binding 11155 10LDLRAP1 ARH low density lipoprote26119 1LGALS9 LGALS9 lectin, galactoside-b 3965 17LGMN LGMN legumain [Source:HG 5641 14LHB LHB luteinizing hormone 3972 19LHCGR LHCGR luteinizing hormone/ 3973 2LIPF LIPF lipase, gastric [Sour 8513 10LLPH LLPH LLP homolog, long-ter84298 12LMO4 LMO4 LIM domain only 4 [S 8543 1LSM1 LSM1 LSM1 homolog, U6 sma27257 8LTA4H LTA4H leukotriene A4 hydro 4048 12LTBR LTBR lymphotoxin beta rec4055 12LUC7L3 LUC7L3 LUC7-like 3 (S. cerev 51747 17MAF MAF v-maf avian musculo 4094 16MAP2K3 MAP2K3 mitogen-activated pr 5606 17MAP3K14 MAP3K14 mitogen-activated protein kinase kinase k 17MAPK1 MAPK1 mitogen-activated pr 5594 22MAPK10 MAPK10 mitogen-activated pr 5602 4MAPK14 MAPK14 mitogen-activated pr 1432 6MARCO MARCO macrophage receptor 8685 2MAT2A MAT2A methionine adenosylt4144 2MAX MAX MYC associated facto4149 14MED1 CRSP2 mediator complex subunit 1 17MED13 MED13 mediator complex sub9969 17MED15 MED15 mediator complex sub51586 22MED6 MED6 mediator complex sub10001 14MEP1B BCDIN3 meprin A, beta 18MGAT1 MGAT1 mannosyl (alpha-1,3- 4245 5MGEA5 MGEA5 meningioma expressed10724 10MICA MICA MHC class I polypept 100507436 6MIPEP MIPEP mitochondrial interm4285 13MKI67 MKI67 marker of proliferati 4288 10MRPS5 MRPS5 mitochondrial riboso 64969 2MSLN MSLN mesothelin [Source: 10232 16MSX2 MSX2 msh homeobox 2 [Sou4488 5MTHFD2 MTHFD2 methylenetetrahydrof10797 2MYCBP2 MYCBP2 MYC binding protein 223077 13MYEF2 MYEF2 myelin expression fa 50804 15MYO1D MYO1D myosin ID [Source:H 4642 17MYOG MYOG myogenin (myogenic f4656 1NACA NACA nascent polypeptide- 4666 12NAGLU NAG/ N-acetylglucosaminidase, alpha 17NDUFB8 NDUFB8 NADH dehydrogenase (4714 10NELFB COBRA1 negative elongation factor complex membe9NELFCD TH1L negative elongation factor complex membe20NELFE RDBP negative elongation factor complex membe6NEUROD4 NEUROD4 neuronal differentia 58158 12

NHP2 NHP2 NHP2 ribonucleoprot 55651 5NLE1 NLE1 notchless homolog 1 54475 17NOP56 NOP56 NOP56 ribonucleopro10528 20NPEPL1 NPEPL1 aminopeptidase-like 79716 20NR2F6 NR2F6 nuclear receptor sub 2063 19NR3C1 NR3C1 nuclear receptor subf2908 5NR3C2 NR3C2 nuclear receptor sub 4306 4NR4A1 NR4A1 nuclear receptor sub 3164 12NRBP1 NRBP1 nuclear receptor bin 29959 2NUDT21 NUDT21 nudix (nucleoside di 11051 16NUP107 NUP107 nucleoporin 107kDa 57122 12NUP153 NUP153 nucleoporin 153kDa 9972 6NUP155 NUP155 nucleoporin 155kDa 9631 5NUP160 NUP160 nucleoporin 160kDa 23279 11NUP62 NUP62 nucleoporin 62kDa [ 23636 19NUP98 NUP98 nucleoporin 98kDa [ 4928 11NXT2 NXT2 nuclear transport fac 55916 XOGDH OGDH oxoglutarate (alpha- 4967 7OGT OGT O-linked N-acetylglu 8473 XOR5P2 OR5P2 olfactory receptor, f 120065 11P2RX4 P2RX4 purinergic receptor P 5025 12PAFAH1B1 PAFAH1B1 platelet-activating f 5048 17PAH PAH phenylalanine hydrox5053 12PAICS PAICS phosphoribosylaminoi10606 4PANK1 PANK1 pantothenate kinase 53354 10PANX3 PANX3 pannexin 3 [Source: 116337 11PAX6 PAX6 paired box 6 [Source 5080 11PAXBP1 GCFC1 PAX3 and PAX7 binding protein 1 21PDE1A PDE1A phosphodiesterase 1 5136 2PDE1B PDE1B phosphodiesterase 1 5153 12PDE5A PDE5A phosphodiesterase 5A8654 4PDE9A PDE9A phosphodiesterase 9 5152 21PES1 PES1 pescadillo ribosomal 23481 22PEX6 PEX6 peroxisomal biogenes5190 6PFKM PFKM phosphofructokinase,5213 12PGK1 PGK1 phosphoglycerate kin5230 XPGM1 PGM1 phosphoglucomutase 5236 1PHEX PHEX phosphate regulating5251 XPIGM PIGM phosphatidylinositol 93183 1PIK3AP1 PIK3AP1 phosphoinositide-3-k 118788 10PIK3C2A PIK3C2A phosphatidylinositol- 5286 11PKM2 PKM pyruvate kinase, muscle 15PLA2G2D PLA2G2D phospholipase A2, gr 26279 1PLCB3 PLCB3 phospholipase C, beta5331 11PLEKHF2 PLEKHF2 pleckstrin homology 79666 8PLGLB1 PLGL plasminogen-like B1 2PLK1 PLK1 polo-like kinase 1 [ 5347 16

PLRG1 PLRG1 pleiotropic regulato 5356 4PLXDC1 PLXDC1 plexin domain contai 57125 17PNPLA4 PNPLA4 patatin-like phospho 8228 XPOLH POLH polymerase (DNA dire5429 6POLR2A RPB1 polymerase (RNA) II (DNA directed) polype17POLR3E POLR3E polymerase (RNA) III 55718 16PPGB PPCDC phosphopantothenoyl60490 15PPM1A PPM1A protein phosphatase 5494 14PPM1B PPM1B protein phosphatase 5495 2PPM1E PPM1E protein phosphatase 22843 17PPM1F PPM1F protein phosphatase 9647 22PPP1R13B PPP1R13B protein phosphatase 23368 14PPP1R3D PPP1R3D protein phosphatase 5509 20PPP2CB PPP2CB protein phosphatase 25516 8PPP2R1B PPP2R1B protein phosphatase 5519 11PPP2R2A PPP2R2A protein phosphatase 5520 8PPP3R2 PPP3R2 protein phosphatase 5535 9PPP5C PPP5C protein phosphatase 5536 19PRDX3 PRDX3 peroxiredoxin 3 [Sou 10935 10PREP PREP prolyl endopeptidase 5550 6PRIM1 PRIM1 primase, DNA, polype5557 12PRPF19 PRPF19 pre-mRNA processing 27339 11PRPF38A PRPF38A pre-mRNA processing 84950 1PRSS22 PRSS22 protease, serine, 22 64063 16PRSS36 FLJ90661 protease, serine, 36 16PRSS41 TESSP1 protease, serine, 41 360226 16PSD3 PSD3 pleckstrin and Sec7 23362 8PSMA1 PSMA1 proteasome (prosome,5682 11PSMA5 PSMA5 proteasome (prosome,5686 1PSMA7 PSMA7 proteasome (prosome,5688 20PSMB3 PSMB3 proteasome (prosome,5691 17PSMB5 PSMB5 proteasome (prosome,5693 14PSMB6 PSMB6 proteasome (prosome,5694 17PSMC5 PSMC5 proteasome (prosome,5705 17PSMD11 PSMD11 proteasome (prosome,5717 17PSMD14 PSMD14 proteasome (prosome,10213 2PSMD2 PSMD2 proteasome (prosome,5708 3PSMD3 PSMD3 proteasome (prosome,5709 17PSMD4 PSMD4 proteasome (prosome,5710 1PSMD8 PSMD8 proteasome (prosome,5714 19PSPC1 PSPC1 paraspeckle compone55269 13PTEN PTEN phosphatase and ten 5728 10PTGES3 PTGES3 prostaglandin E synth10728 12PTP4A3 PTP4A3 protein tyrosine pho 11156 8PTPRE PTPRE protein tyrosine pho 5791 10PUM2 PUM2 pumilio RNA-binding 23369 2PUS3 PUS3 pseudouridylate synt 83480 11

PXDNL PXDNL peroxidasin homolog 137902 8PYGM PYGM phosphorylase, glyco 5837 11QDPR QDPR quinoid dihydropteri 5860 4QTRT1 QTRT1 queuine tRNA-ribosyl81890 19RAB10 RAB10 RAB10, member RAS o10890 2RAB11A RAB11A RAB11A, member RAS 8766 15RAB20 RAB20 RAB20, member RAS o55647 13RAB28 RAB28 RAB28, member RAS o9364 4RAB37 RAB37 RAB37, member RAS o326624 17RAD51C RAD51C RAD51 paralog C [So 5889 17RANBP2 RANBP2 RAN binding protein 5903 2RAP1B RAP1B RAP1B, member of RA5908 12RCL1 RCL1 RNA terminal phospha10171 9RHEB RHEB Ras homolog enriched6009 7RIMS4 RIMS4 regulating synaptic 140730 20RMND5A RMND5A required for meiotic 64795 2RNF130 RNF130 ring finger protein 55819 5RNMT RNMT RNA (guanine-7-) met8731 18RPAP3 RPAP3 RNA polymerase II as 79657 12RPL11 RPL11 ribosomal protein L1 6135 1RPL13 RPL13 ribosomal protein L1 6137 16RPL14 RPL14 ribosomal protein L1 9045 3RPL19 RPL19 ribosomal protein L1 6143 17RPL21 RPL21 ribosomal protein L2 6144 13RPL23 RPL23 ribosomal protein L2 619505 17RPL23A RPL23A ribosomal protein L2 6147 17RPL24 RPL24 ribosomal protein L2 6152 3RPL6 RPL6 ribosomal protein L6 6128 12RPL7 RPL7 ribosomal protein L7 6129 8RPL8 RPL8 ribosomal protein L8 6132 8RPLP2 RPLP2 ribosomal protein, l 6181 11RPS15A RPS15A ribosomal protein S1 6210 16RPS26 RPS26 ribosomal protein S2 6231 12RPS3A RPS3A ribosomal protein S3 6189 4RPS5 RPS5 ribosomal protein S5 6193 19RRM2B RRM2B ribonucleotide reduc 50484 8RRP1 D21S2056E/ ribosomal RNA processing 1 homolog (S. cer21RSPRY1 RSPRY1 ring finger and SPRY 89970 16SBDS SBDS Shwachman-Bodian-D51119 7SDF4 SDF4 stromal cell derived 51150 1SEC13 SEC13 SEC13 homolog (S. ce6396 3SEC23A SEC23A Sec23 homolog A (S. 10484 14SEC61A2 SEC61A2 Sec61 alpha 2 subunit55176 10SEC61G SEC61G Sec61 gamma subunit23480 7SEC62 SEC62 SEC62 homolog (S. ce7095 3SF3A3 SF3A3 splicing factor 3a, s 10946 1

SF3B2 SF3B2 splicing factor 3b, s 10992 11SF3B3 SF3B3 splicing factor 3b, s 23450 16SFTPD SFTPD surfactant protein D 6441 10SGTA SGTA small glutamine-rich 6449 19SH3GL1 SH3GL1 SH3-domain GRB2-lik6455 19SIN3A SIN3A SIN3 transcription r 25942 15SIRT1 SIRT1 sirtuin 1 [Source:HG 23411 10SKIV2L2 SKIV2L2 superkiller viralicidi 23517 5SLC25A10 SLC25A10 solute carrier family 1468 17SLC25A19 SLC25A19 solute carrier famil 60386 17SLC25A21 SLC25A21 solute carrier family 89874 14SLC25A4 SLC25A4 solute carrier family 291 4SLC2A3 SLC2A3 solute carrier family 6515 12SLC33A1 SLC33A1 solute carrier family 9197 3SLC35F5 SLC35F5 solute carrier famil 80255 2SLC39A2 SLC39A2 solute carrier family 29986 14SLC41A1 SLC41A1 solute carrier famil 254428 1SLC50A1 SLC50A1 solute carrier family 55974 1SLC7A4 SLC7A4 solute carrier famil 6545 22SLU7 SLU7 SLU7 splicing factor 10569 5SMARCA4 SMARCA4 SWI/SNF related, mat6597 19SMARCB1 SMARCB1 SWI/SNF related, mat6598 22SMARCC2 SMARCC2 SWI/SNF related, mat6601 12SMG1 SMG1 SMG1 phosphatidylino101060589 16SMG5 SMG5 SMG5 nonsense media23381 1SMYD2 SMYD2 SET and MYND domain56950 1SNAP25 SNAP25 synaptosomal-associa6616 20SNAP29 SNAP29 synaptosomal-associa9342 22SnRNP200 SNRNP200 small nuclear ribonu 23020 2SNRPB SNRPB small nuclear ribonu 6628 20SNRPB2 SNRPB2 small nuclear ribonu 6629 20SNRPD1 SNRPD1 small nuclear ribonu 6632 18SNRPF SnRNPF small nuclear ribonuc6636 12SNW1 SNW1 SNW domain containi22938 14SNX27 SNX27 sorting nexin family 81609 1SOD1 SOD1 superoxide dismutase6647 21SORCS1 SORCS1 sortilin-related VPS 114815 10SPG20 SPG20 spastic paraplegia 2 23111 13SPHK2 SPHK2 sphingosine kinase 2 56848 19SPOCK1 SPOCK1 sparc/osteonectin, cw6695 5SPON1 SPON1 spondin 1, extracellu 10418 11SRCAP SRCAP Snf2-related CREBBP 10847 16SREBF2 SREBF2 sterol regulatory ele 6721 22SREK1 SFRS12 splicing regulatory glutamine/lysine-rich pr5SSR4 SSR4 signal sequence rece 6748 XSSRP1 SSRP1 structure specific re 6749 11

SSSCA1 SSSCA1 Sjogren syndrome/scl10534 11STIP1 STIP1 stress-induced-phosp10963 11STUB1 STUB1 STIP1 homology and U-10273 16STX1A STX1A syntaxin 1A (brain) 6804 7SULT1A2 SULT1A2 sulfotransferase fami6799 16SUMO3 SUMO3 small ubiquitin-like 6612 21SUPT5H SUPT5H suppressor of Ty 5 h 6829 19SYNE1 SYNE1 spectrin repeat cont 23345 6SYNRG AP1GBP1 synergin, gamma 11276 17TAF4B TAF4B TAF4b RNA polymerase6875 18TAF9B TAF9B TAF9B RNA polymerase51616 XTAOK1 TAOK1 TAO kinase 1 [Sourc 57551 17TBC1D26 MGC51025 TBC1 domain family, member 26 17TBCE TBCE tubulin folding cofa 6905 1TEKT1 TEKT1 tektin 1 [Source:HGN 83659 17TFDP2 TFDP2 transcription factor 7029 3TFPI2 TFPI2 tissue factor pathway7980 7TIMM8A TIMM8A translocase of inner 1678 XTLR3 TLR3 toll-like receptor 3 7098 4TMEM30A TMEM30A transmembrane prote55754 6TMEM38B TMEM38B transmembrane prote55151 9TMPRSS4 TMPRSS4 transmembrane protea56649 11TMPRSS5 TMPRSS5 transmembrane protea80975 11TNFSF13B TNFSF13B tumor necrosis facto 10673 13TNFSF18 TNFSF18 tumor necrosis facto 8995 1TOMM20 TOMM20 translocase of outer 9804 1TOMM22 TOMM22 translocase of outer 56993 22TP53INP1 TP53INP1 tumor protein p53 in 94241 8TP53RK TP53RK TP53 regulating kina 112858 20TPSD1 TPSD1 tryptase delta 1 [So 23430 16TPT1 TPT1 tumor protein, transl 7178 13TRAF3 TRAF3 TNF receptor-associa 7187 14TRAPPC2 TRAPPC2 trafficking protein p 6399 XTREH TREH trehalase (brush-bor 11181 11TRIM71 TRIM71 tripartite motif cont 131405 3TRPV6 TRPV6 transient receptor p 55503 7TRRAP TRRAP transformation/trans 8295 7TSG101 TSG101 tumor susceptibility 7251 11TTC19 TTC19 tetratricopeptide re 54902 17TTC36 TTC36 tetratricopeptide re 143941 11TTl1 KIAA0406 TELO2 interacting protein 1 20TUBB4B TUBB2C tubulin, beta 4B class IVb 9TUBG1 TUBG1 tubulin, gamma 1 [S 7283 17TXNDC9 TXNDC9 thioredoxin domain c10190 2UBA1 UBA1 ubiquitin-like modifi 7317 XUBA2 UBA2 ubiquitin-like modifi 10054 19UBC UBC ubiquitin C [Source: 7316 12

UBE1 UBA1 ubiquitin-like modifier activating enzyme 1 XUBE2D2 UBE2D2 ubiquitin-conjugatin 7322 5UBE2H UBE2H ubiquitin-conjugatin 7328 7UBE2I UBE2I ubiquitin-conjugatin 7329 16UBE2K UBE2K ubiquitin-conjugatin 3093 4UCHL3 UCHL3 ubiquitin carboxyl-te 7347 13UGP2 UGP2 UDP-glucose pyropho7360 2UGT3A2 UGT3A2 UDP glycosyltransfer 167127 5UPF1 UPF1 UPF1 regulator of no 5976 19UPF2 UPF2 UPF2 regulator of no 26019 10UPRT UPRT uracil phosphoribosyl139596 XUQCC1 UQCC ubiquinol-cytochrome c reductase complex 20USP1 USP1 ubiquitin specific pe 7398 1USP21 USP21 ubiquitin specific pe 27005 1USP7 USP7 ubiquitin specific pe 7874 16USP8 USP8 ubiquitin specific pe 9101 15USPL1 C13ORF22 ubiquitin specific peptidase like 1 13VBP1 VBP1 von Hippel-Lindau bi 7411 XVPRBP VPRBP Vpr (HIV-1) binding 9730 3VPS26B VPS26B vacuolar protein sor 112936 11VPS54 VPS54 vacuolar protein sort 51542 2WDR18 WDR18 WD repeat domain 1857418 19WDR43 WDR43 WD repeat domain 4323160 2WDR5 WDR5 WD repeat domain 5 11091 9XAB2 XAB2 XPA binding protein 56949 19YBX1 YBX1 Y box binding protei 4904 1YWHAE YWHAE tyrosine 3-monooxyge7531 17YWHAZ YWHAZ tyrosine 3-monooxyge7534 8ZCCHC8 ZCCHC8 zinc finger, CCHC do 55596 12ZFP36L2 ZFP36L2 ZFP36 ring finger pro 678 2ZFYVE20 ZFYVE20 zinc finger, FYVE do 64145 3ZNF207 ZNF207 zinc finger protein 7756 17ZNF24 ZNF24 zinc finger protein 7572 18ZSCAN5B ZSCAN5B zinc finger and SCAN 342933 19

Band Gene Start (bp) Gene End (bp) Transcript count Based on their effectq24.31 125549925 125627873 14 Suppressorq26.31 Enhancerq22.3 105946228 105969437 5 Enhancerq11.2 23067146 23081265 10 Enhancerq12 35441923 35766909 26 Suppressorp31.1 76190036 76253260 19 Suppressorp11.2 47260853 47270457 15 Enhancerq22.1 132036211 132087142 9 Suppressor*p21.2 52009066 52023213 12 Enhancerq24.2 70918874 70926622 2 Suppressor*p11.22 38854388 38962663 9 Suppressor*q12.3 64444563 64777747 9 Suppressor*p16.3 2845584 2931803 28 Enhancerp11.21 12328943 12377313 4 Suppressorq Enhancerq13.2 67250512 67258574 4 Suppressor*p11.2 30064411 30081778 27 Enhancerq22.33 101978708 101984238 3 Suppressorp31.3 63833261 63904233 7 Enhancerq25.3 Enhancerp13.11 16308389 16346160 16 Suppressorq13.32 47341393 47354249 10 Suppressorq23.2 86968431 86970909 Suppressorq13.1 39436609 39449915 4 Suppressor*q21.3 27252861 27543446 19 Suppressor*q24.3 88875747 88878352 11 Suppressorp21.1 32972604 33025166 33 Suppressor*p13.3 33441152 33447609 5 Enhancerp12.1 25227052 25240261 2 Suppressorq12 66764465 66950461 6 Suppressor*q28 153929827 153935154 Enhancerp14.3 57557090 57583947 9 Enhancerp11.2 46698630 46722165 7 Suppressorq22.33 129897277 130031370 3 Suppressorq13.12 36265434 36279724 13 Suppressorq13.32 Enhancerq25.2 153838792 153975616 5 Suppressorq13.1 64781585 64789656 6 Enhancerp15.2 13298199 13408813 24 Enhancerq22.1 98923521 98985787 7 Suppressor*p13.11 18111941 18124911 9 Enhancerq23.3 108168162 108170421 1 Suppressorp13.12 14230321 14247768 5 Enhancerp11.23 37962760 38001594 13 Suppressorq21.3 97481430 97501854 17 Enhancer

p23.3 23971534 24149984 9 Enhancerq33.1 151121877 151152093 7 Enhancerq21.1 43664110 43684300 20 Suppressorp14 7830092 7849778 11 Suppressor*p13.2 111991486 112005395 6 Enhancerq21.2 40610862 40674629 26 Enhancerp21 46717889 46769696 6 Suppressorq21.1 77166194 77305892 3 Suppressorq24.12 111890018 112037480 26 Enhancerp14.3 32535038 33078516 9 Enhancerq23.3 117156402 117186975 12 Suppressor*q22.2 42539728 42654445 10 Suppressor*p21.3 Enhancerq13.2 41884215 41930910 9 Suppressorq15 70037140 70093256 13 Enhancerp25.2 3118608 3153812 12 Suppressorp15.2 13409548 13484844 11 Enhancerq21.33 92536286 92539673 2 Enhancerq13 111395275 111435691 12 Enhancerq26.13 124913793 124924886 6 Enhancerp13.2 Enhancerp13.3 Enhancerq13.31 Suppressorq13 Enhancerq24 Suppressor*p22.1 6629648 6648357 6 Suppressorq22.32 97488983 97849441 25 Suppressor*q25.3 181382238 181777219 9 Suppressor*q32.1 128379346 128411861 8 Enhancerp13 12391481 12877545 3 Suppressorq41 223889295 223963720 12 Suppressor*p36.13 19665267 19812066 11 Suppressorp11.4 41374187 41782716 15 Suppressorq35.1 185548850 185570663 6 Suppressor*q11.21 32077881 32237842 11 Suppressor*p15.2 24807739 24981826 8 Enhancerq13.3 69455855 69469242 6 Suppressorq12 30302805 30315215 7 Enhancerq14.3 86687311 86708836 10 Enhancerq21.1 77968311 77997158 10 Enhancerp15 62095224 62115939 6 Suppressorp15.2 10250033 10266524 14 Suppressorq12 33254878 33308097 5 Suppressorp13.2 73460548 73480149 18 Suppressorp13.31 6896024 6929974 12 Suppressor*p21.1 44355262 44418163 1 Enhancerq11.21 31946645 31989367 17 Enhancer

q13.2 68530668 68573250 13 Enhancerp11 Suppressor*p25.1 14153580 14166370 3 Enhancerq13.33 51017378 51039884 12 Suppressorp13.3 838046 850737 19 Suppressorq32.32 103985996 103989448 17 Enhancerq21.13 90013035 90142716 16 Suppressor*p33 47799469 47844511 5 Suppressorq11.2 98962618 99015064 5 Suppressor*p22 17086737 17104387 12 Enhancerq25.1 71189129 71204646 9 Suppressorq22.33 101705461 101833069 4 Enhancerq22.3 107683074 107940775 10 Suppressorp25.3 3642426 3692048 13 Enhancerp25.1 15491640 15563258 11 Suppressorp13.11 19010323 19030206 11 Enhancerq13.1 67955314 67996018 13 Suppressorq32.2 130020180 130027955 9 Suppressor*q32.2 129906667 129929638 4 Enhancerq24 148508889 148577974 10 Suppressor*q33.3 207804278 207834198 1 Suppressor*q34 211342406 211543831 11 Suppressorq32.12 92588281 92630755 5 Enhancerp25.1 9563697 9613230 5 Enhancerp36.33 1246965 1260071 48 Suppressorp32.3 53662101 53679869 2 Suppressorp13.2 12764761 12798042 2 Suppressor*q32.33 105952654 105955284 6 Suppressorp12.3 49695097 49712150 6 Enhancerp11.23 20015012 20036690 7 Enhancerq13.3 56665483 56694176 33 Suppressorp13 459116 524465 9 Enhancerp21.33 31633013 31638120 8 Enhancerp31.1 70876901 70905534 5 Suppressorq11.23 36322408 36500531 8 Enhancerp13.2 3539762 3564836 12 Enhancerp15.5 1773982 1785222 6 Suppressorq36.1 148395006 148498128 3 Enhancerp11.21 35297479 35379570 11 Enhancerq12.1 50775961 50835846 17 Suppressor*q23.33 96796530 96829254 11 Enhancerq22.1 99245817 99277621 16 Enhancerp13.1 39371780 39462402 17 Enhancerp21.32 33286335 33297046 12 Suppressor*q32.12 94517266 94547591 8 Suppressorq23.3 62495734 62504317 34 Suppressorq11.21 19117792 19132197 4 Enhancer

q21.31 41561233 41621831 7 Enhancerq24.31 122692210 122712081 15 Suppressor*q31.3 140894583 140998622 18 Suppressorq21.33 48046334 48052321 5 Suppressor*q21.12 86781677 86825653 41 Suppressor*p21.1 33025209 33039905 4 Suppressorp13.2 Suppressorq22.1 74092588 74114988 6 Enhancerp31.1 78444859 78483648 6 Suppressorq14.1 83777385 83881069 8 Suppressorq22.1 68009566 68014732 2 Suppressor*p22.1 93811445 93835055 3 Suppressorp15.5 1575274 1593150 3 Enhancerq25.3 159057506 159065771 3 Suppressorp14 11784365 11806069 5 Enhancerq34.3 139756571 139760738 3 Enhancerp13.3 3976054 3985467 7 Suppressorq21.31 42927311 42977030 26 Suppressorp22-p21 Suppressor*p11.2 88856259 88927094 6 Suppressorq24.31 124104953 124118313 6 Suppressorq11.22 32676104 32700138 1 Suppressorp22.11 24072833 24096088 5 Suppressorq26.11 120794356 120840316 3 Suppressorp22 Enhancerq23.1 109213445 109447562 18 Suppressorp34.1 Enhancerp36.12 21132963 21503377 18 Enhancerq32.32 103799881 103811362 21 Suppressorq25 111286889 111486441 5 Suppressor*q24.1 97471536 97637023 12 Suppressorq34.3 139942550 139948497 4 Suppressorp22.1 40428647 40470110 4 Suppressorp21.2 23243296 23315208 11 Suppressorq24.3 74424713 74486102 8 Suppressorp11.21 25176329 25207365 18 Suppressorq24.2 101419263 101465997 2 Suppressorq34.3 140328816 140336268 5 Suppressorq13.42 55583388 55599291 19 Enhancerq14.3 128014866 128051752 10 Enhancerq31.2 137841784 137878989 9 Suppressorq33 132937829 133751342 27 Suppressorp11.2 88422510 88427635 4 Suppressor*p35.2 31838472 31849697 4 Enhancerq21.13 82192598 82197012 4 Suppressor*q12.2 61567099 61596790 21 Enhancerq13.2 31196055 31235311 8 Suppressor

q36.1 223435255 223521056 2 Suppressorq25.3 80036214 80056208 6 Suppressorq13.31 45898118 45997015 19 Enhancerq13.2 72251808 72386349 8 Enhancerq12.2 61560109 61564716 3 Suppressorq12.2 33877677 34360018 10 Suppressorq13.1 64008475 64011604 6 Suppressorp11.21 42889337 42940931 15 Suppressorp24.3 116237 118417 1 Suppressorq13.41 52255279 52273779 6 Suppressorq13.41 52298416 52329442 2 Suppressorp36 Enhancerq12.3 61727190 61735132 11 Enhancerp13.1 7143333 7146089 6 Enhancerq42.13 230193536 230417870 7 Enhancerp13.31 6643093 6647537 10 Enhancerq21.2 Suppressor*q21.13 79034752 79122332 6 Suppressorq11.22 48425815 48438976 1 Suppressor*q13.13 Enhancerp13.3 69546905 69614382 4 Enhancerp13.3 660337 685581 17 Suppressorq33.1 151202074 151304403 5 Suppressor*p22.2 14547420 14749934 4 Suppressor*p25.3 1624041 2245926 10 Enhancerp13.3 848041 850733 1 Enhancerq24.2 101156627 101190381 4 Enhancerq13.11 34850385 34893061 17 Enhancerp13.1 13093709 13105081 3 Suppressor*q34.3 140032842 140063207 14 Suppressor*p13.2 9852376 10276611 12 Suppressor*p13.1 13693165 14133053 1 Suppressor*q13.33 119540170 119813264 4 Suppressorq11.22 33516236 33543620 3 Suppressorq13.2 67351066 67354131 9 Suppressorq34.2 135906076 135933890 11 Enhancerp12 44680444 44702943 4 Enhancerq13.12 35771619 35776046 3 Suppressor*q24.31 Suppressor*p12 45259349 45696253 1 Suppressor*q21 114254192 114332472 18 Suppressorq37.3 242166679 242256476 47 Suppressor*q13.3 73935848 74018472 13 Enhancerq13.33 120347020 120401418 10 Suppressor*q23.2 62162231 62214976 12 Suppressor*p22.2 26234440 26235216 1 Enhancerp22.2 26124373 26139344 3 Enhancer

p22.1 27775257 27775709 1 Enhancerp22.1 27777842 27778314 1 Enhancerq21.2 149825607 149832714 3 Enhancerq13.3 74632154 74657929 13 Enhancerp12 120290619 120311528 4 Suppressorp25.3 11178779 11305243 4 Suppressor*q35.2 175085033 175113245 2 Suppressor*q13.33 49316274 49339935 4 Enhancerq23.3 82068609 82132139 6 Suppressorq32 115142217 115234690 7 Suppressorq24.3 145515280 145538385 13 Suppressorq32.31 102547075 102606036 11 Suppressorq31.1 132387654 132442141 3 Suppressorq33.3 127997132 128003609 1 Enhancerq31.2 137890571 137911133 13 Suppressorp11.1 88039846 88042919 1 Suppressor*p34.2 43916824 43919660 14 Enhancerp12.1 52866077 52926600 2 Suppressor*q13.4 71709587 71716761 13 Suppressor*q12.1 102927989 103015218 5 Suppressor*q32.1 206972215 207016324 3 Suppressor*q12-q14.1 Suppressorq28 190231840 190375843 19 Suppressor*p15.4 6624961 6632102 17 Suppressor*q23.2 59942731 60005377 6 Suppressorq14.1 77589766 77705724 11 Suppressorq32.3 212113741 212208884 9 Suppressorq22.1 95825539 95893974 21 Suppressorp21.1 Suppressorq32.2 98605912 98676551 29 Suppressorq22.31 95375466 95432547 3 Suppressorq21.3 128846258 128880136 7 Enhancerp13.11 18390563 18392432 2 Suppressorp22.31 8496915 8700227 3 Enhancerq21.33 47865917 47906458 19 Suppressorp15.1 17756359 17804602 4 Enhancerq14.2 50589390 50595058 2 Suppressorq41 215740735 215795149 5 Enhancerp21.31 44779153 44803154 2 Enhancerq23.33 94353043 94415150 1 Enhancerp22.3 17759414 17987854 13 Suppressorq32.1 200938520 200992828 5 Suppressor*q23 69706585 69740764 14 Suppressor*p21.32 33359313 33377701 4 Suppressor*q21.12 72999503 73029540 1 Suppressorq22.1 Suppressor*q24-q26 Suppressor

q23.2 88428206 88495825 10 Enhancerp36-p35 Suppressor*q11.2 25956824 25976586 18 Suppressor*q32.12 93170152 93215047 19 Suppressor*q13.33 49519237 49520338 1 Suppressor*p16.3 48859428 48982880 9 Suppressor*q23.31 90424198 90438571 6 Suppressorq14.3 66516842 66524548 2 Enhancerp22.3 87794151 87814606 4 Suppressorp11.23 38020839 38034248 5 Enhancerq23.1 96394606 96437298 10 Enhancerp13.31 6484211 6500733 15 Suppressor*q21.33 48796905 48833574 24 Suppressorq23.2 79619740 79634611 3 Enhancerp11.2 21187984 21218552 13 Enhancerq21.31 43340488 43394414 5 Suppressor*q11.22 22108789 22221970 4 Suppressorq21.3 86936276 87515284 35 Enhancerp21.31 35995488 36079013 9 Enhancerq14.2 119699742 119752236 4 Enhancerp11.2 85766288 85772403 6 Suppressorq23.3 65472892 65569413 18 Suppressorq12 Suppressor*q23.2 60019966 60142643 6 Suppressorq11.21 20850200 20941919 34 Enhancerq24.2 71047974 71067384 11 Enhancerq12.2-q12.3 Suppressorq35.3 180217541 180242652 25 Enhancerq24.32 103544200 103578696 12 Enhancerp21.33 31371356 31383092 2 Suppressor*q12.12 24304328 24463558 5 Suppressor*q26.2 129894923 129924649 5 Suppressor*q11.1 95752952 95815179 8 Enhancerp13.3 810762 818865 8 Suppressor*q35.2 174151536 174157896 2 Suppressorp13.1 74425689 74444692 10 Enhancerq22.3 77618792 77901185 13 Suppressorq21.1 48431625 48470714 14 Suppressorq11.2 30819540 31204195 15 Suppressorq32.1 203052260 203055164 1 Enhancerq13.3 57106212 57125412 21 Enhancerq21.2 Suppressorq24.31 102267203 102289757 10 Enhancerq34 Suppressorq13 Suppressorp21.3 Suppressorq13.2 55413729 55423798 1 Suppressor

q35.3 177576461 177580968 6 Enhancerq12 33455772 33469334 7 Suppressorp13 2632791 2639039 18 Enhancerq13.32 57264187 57294294 9 Enhancerp13.11 17342692 17356749 2 Suppressor*q31.3 142657496 142815077 17 Suppressor*q31.23 148999913 149365850 9 Suppressor*q13.13 52416616 52453291 22 Suppressor*p23.3 27650657 27665126 9 Enhancerq12.2 56463045 56486111 6 Enhancerq15 69080514 69136785 13 Enhancerp22.3 17615269 17706656 2 Enhancerp13.2 37288239 37371283 8 Enhancerp11.2 47799639 47870107 12 Enhancerq13.33 50410082 50433020 24 Enhancerp15.4 3692313 3819022 20 Enhancerq23 108779010 108787919 4 Enhancerp13 44646171 44748665 10 Suppressorq13.1 70752933 70795747 11 Enhancerp15.4 7817452 7818520 1 Suppressor*q24.31 121647660 121671909 15 Suppressor*p13.3 2496504 2588909 14 Suppressor*q23.2 103230663 103352188 15 Suppressor*q12 57301907 57327534 8 Enhancerq23.31 91342745 91405215 6 Enhancerq24.2 124481386 124490252 1 Enhancerp13 31806340 31839509 30 Enhancerq22.11 Enhancerq32.1 183004763 183387919 13 Suppressor*q13.2 54943134 54973023 8 Suppressor*q26 120415550 120550146 12 Suppressor*q22.3 44073746 44195619 29 Suppressor*q12.2 30972612 31003070 13 Suppressorp21.1 42931608 42946958 2 Suppressor*q13.11 48498922 48540187 32 Suppressorq21.1 77320685 77384793 7 Enhancerp31.3 64058947 64125916 5 Suppressorp22.11 22050559 22269427 5 Suppressor*q23.2 159997462 160001783 1 Suppressorq24.1 98353069 98480271 6 Suppressor*p15.1 17099277 17229530 6 Suppressorq23 Enhancerp36.12 20438432 20446050 1 Suppressor*q13.1 64018995 64036622 4 Suppressor*q22.1 96146032 96168912 2 Suppressorp11.2 Suppressor*p12.2 23688977 23701688 9 Enhancer

q31.3 155456158 155471587 14 Enhancerq12 37219556 37310647 22 Suppressorp22.31 7866288 7895780 4 Suppressorp21.1 43543887 43586701 4 Suppressor*p13.1 Suppressorp12.2 22308730 22346424 18 Enhancerq24.2 75315896 75409803 11 Suppressor*q23.1 60712470 60765805 9 Suppressor*p21 44395108 44471523 12 Suppressorq22 56833230 57058983 1 Suppressor*q11.22 22273793 22307209 10 Enhancerq32.33 104200089 104313927 18 Suppressor*q13.33 58511894 58515352 1 Suppressor*p12 30631973 30671830 10 Enhancerq23.1 111597632 111637151 13 Suppressor*p21.2 26149007 26230196 23 Suppressorq31.1 104353897 104357283 1 Suppressor*q13.32 46850251 46896238 15 Enhancerq26.11 120927215 120938345 4 Enhancerq21 105725440 105850959 2 Suppressor*q13.3 57125380 57146157 8 Enhancerq12.2 60658202 60674060 7 Enhancerp32.3 52870236 52886511 3 Suppressorp13.3 2902728 2908171 8 Suppressorp11.2 Suppressor*p13.3 Suppressor*p22 18384811 18942240 18 Suppressorp15.2 14515329 14665181 16 Suppressorp13.3 109941653 109969062 6 Enhancerq13.33 60711791 60718496 6 Suppressorq12 36908989 36920484 6 Suppressorq11.2 23485752 23504439 6 Suppressor*p13.2 4699439 4701790 4 Enhancerq23.3 61904512 61909379 21 Suppressorq11.2 30771279 30810336 11 Suppressorq24.2 162164549 162268228 5 Suppressorq27.1 184016497 184026842 20 Enhancerq21.1 38137050 38154213 6 Enhancerq21.3 151227179 151239955 12 Enhancerq13.2 38865176 38874464 9 Enhancerq12.11 20248896 20357142 5 Suppressorq23.31 89622870 89731687 5 Suppressorq13.3 57057127 57082159 6 Suppressorq24.3 142402093 142441620 6 Suppressor*q26.2 129705325 129884119 13 Suppressor*p24.1 20448452 20551995 12 Enhancerq24.2 125763381 125773116 4 Enhancer

q11.23 52232138 52722005 5 Suppressorq13.1 64513861 64527769 5 Suppressorp15.32 17461884 17513857 9 Suppressorp13.2 10812106 10824113 12 Enhancerp23.3 26256976 26360323 4 Enhancerq22.31 66018392 66184329 10 Enhancerq34 111175417 111214080 1 Suppressor*p15.33 13362978 13485989 7 Enhancerq25.1 72666717 72743474 15 Enhancerq22 56769934 56811703 17 Suppressor*q12.3 109335937 109402267 4 Enhancerq15 69004619 69054372 33 Enhancerp24.1 4792869 4885917 9 Enhancerq36.1 151163098 151217206 7 Enhancerq13.12 43380449 43438979 2 Suppressorp11.2 86947296 87005164 4 Enhancerq35.3 179338651 179499118 8 Suppressor*p11.21 13726659 13764557 11 Suppressor*q13.11 48057070 48099844 7 Enhancerp36.11 24018269 24022915 5 Suppressorq24.3 89627065 89630950 15 Suppressorp22.1 40498783 40503861 9 Suppressorq12 37356536 37360980 8 Suppressorq12.2 27825446 27830828 10 Suppressorq12 37004118 37010096 11 Suppressorq11.2 27046411 27051377 9 Suppressorq12.3 101399935 101405626 6 Suppressorq24.13 112842994 112856642 13 Suppressorq21.11 74202506 74208024 8 Suppressorq24.3 146015150 146017972 14 Suppressorp15.5 809647 812880 8 Suppressorp12.3 18792617 18801705 13 Enhancerq13.2 56435637 56438116 3 Suppressorq31.3 152020725 152025804 15 Suppressorq13.43 58897767 58906173 9 Suppressorq22.3 103216730 103251346 10 Enhancerq22.3 Enhancerq13 57220049 57274387 12 Suppressorq11.21 66452664 66460588 4 Enhancerp36.33 1152288 1167411 8 Enhancerp25.3 10334815 10362862 19 Enhancerq21.1 39501123 39578850 15 Enhancerp14 12171636 12211960 14 Enhancerp11.2 54819943 54827667 7 Suppressorq26.2 169684423 169716161 10 Enhancerp34.3 38422647 38456593 9 Suppressor

q13.1 65818200 65836779 16 Enhancerq22.1 70557691 70608820 14 Suppressorq22.3 81697496 81742370 2 Enhancerp13.3 2754712 2783369 5 Suppressorp13.3 4360367 4400544 6 Enhancerq24.2 75661720 75748183 15 Suppressorq21.3 69644427 69678147 6 Enhancerq11.2 54603588 54721409 10 Enhancerq25.3 79670404 79688042 9 Enhancerq25.1 73269073 73285591 15 Suppressorq13.3 37147636 37642071 5 Enhancerq35.1 186064395 186071536 2 Enhancerp13.31 8071826 8088871 11 Enhancerq25.31 155538813 155572218 6 Enhancerq14.1 114462588 114514400 12 Enhancerq11.2 21467414 21470030 3 Suppressorq32.1 205758221 205782876 4 Suppressorq22 155107820 155111329 13 Enhancerq11.21 21383007 21387129 3 Suppressorq33.3 159828648 159848718 9 Enhancerp13.2 11071598 11176071 20 Enhancerq11.23 24129150 24176703 7 Enhancerq13.2 56556767 56583351 15 Enhancerp12.3 18816175 18937776 17 Suppressorq22 156219015 156252620 6 Suppressorq32.3 214454445 214510474 7 Enhancerp12.2 10199478 10288066 5 Suppressorq11.21 21213271 21245506 3 Enhancerq11.2 96940074 96971297 9 Suppressorp13 2442280 2451499 4 Enhancerp12.1 16710606 16722421 3 Enhancerq11.2 19192228 19210417 3 Enhancerq23.1 Suppressorq24.3 78183942 78227550 7 Enhancerq21.3 151584541 151671567 5 Enhancerq22.11 33031935 33041244 4 Enhancerq25.1 108333421 108924292 8 Suppressor*q13.3 36875775 36944317 11 Enhancerq13.33 49122548 49133974 14 Suppressorq31.2 136310987 136934068 10 Suppressorp15.2 13983914 14289646 3 Enhancerp11.2 30709530 30755602 7 Suppressorq13.2 42229109 42303312 8 Enhancerq11.2-q12.1 Enhancerq28 153058971 153063960 12 Enhancerq12.1 57093459 57103351 4 Suppressor

q13.1 65337901 65341413 7 Suppressorq13.1 63952744 63972015 12 Suppressorp13.3 730224 732870 11 Suppressorq11.23 73113536 73134002 14 Enhancerp11.2 28603264 28608430 5 Suppressorq22.3 46225532 46238694 6 Enhancerq13.2 39926796 39967310 19 Suppressorq25.2 152442819 152958936 41 Enhancerq12 37514797 37609496 Suppressor*q11.2 23805900 23971649 4 Suppressorq21.1 77385245 77395203 2 Suppressorq11.2 27717482 27878922 6 Suppressorp11.2 Suppressor*q42.3 235530675 235612283 7 Suppressorp13.1 6692452 6735080 6 Enhancerq23 141663277 141868386 27 Suppressorq21.3 93514709 93520303 4 Suppressorq22.1 100600649 100604184 2 Suppressorq35.1 186990306 187009223 5 Suppressorq14.1 75962640 75994684 4 Suppressorq31.2 108456825 108538893 5 Suppressorq23.3 117947753 117992605 18 Suppressor*q23.2 113558272 113577095 12 Suppressor*q33.3 108903588 108960832 6 Suppressor*q25.1 173009100 173020103 2 Suppressor*q42.3 235272651 235292251 3 Enhancerq13.1 39077953 39080818 2 Suppressorq22.1 95938200 95961639 3 Suppressorq13.12 45313004 45318418 2 Suppressor*p13.3 1306060 1308532 2 Suppressor*q14.13 45911008 45915505 13 Enhancerq32.32 103243813 103377837 9 Suppressorp22.2 13730363 13752754 10 Suppressorq23.3 118528026 118550399 7 Enhancerp22.3 32859510 32939318 1 Suppressorq34 142568956 142583507 8 Suppressor*q22.1 98475556 98610866 6 Suppressorp15.1 18489883 18548779 13 Enhancerp12 15902694 15948329 11 Suppressorq23.3 118398187 118401912 4 Suppressorq11.23 Suppressorq34.3 Enhancerq21.2 40761694 40767252 5 Enhancerq11.2 99935445 99957165 9 Enhancerp11.23 47050260 47074527 9 Suppressorq13.11 34919257 34960853 10 Enhancerq24.31 125396150 125401914 14 Suppressor

p11.23 Suppressorq31.2 138906016 139008018 8 Suppressorq32.2 129470572 129592789 9 Suppressorp13.3 1355548 1377019 20 Suppressorp14 39699664 39784412 8 Enhancerq22.2 76123619 76180085 5 Suppressor*p15 64068074 64118696 28 Enhancerp13.2 36035119 36071460 6 Enhancerp13.11 18942747 18979045 13 Suppressorp14 11962021 12085169 4 Suppressorq13.3 74493920 74524435 8 Enhancerq11.22 Enhancerp31.3 62901968 62917475 4 Suppressor*q23.3 161129240 161135513 10 Suppressor*p13.2 8985951 9058371 22 Suppressorq21.2 50716577 50793280 19 Suppressorq12-q14 Suppressor*q28 154425284 154468098 4 Suppressorp21.2 51433298 51534010 3 Enhancerq25 134094539 134117686 7 Enhancerp14 64119280 64246206 4 Suppressorp13.3 983174 994569 11 Suppressorp23.2 29117509 29171088 6 Enhancerq34.2 137000487 137025093 4 Enhancerp13.2 7684411 7694451 5 Enhancerp34.2 43148098 43168020 4 Enhancerp13.3 1247566 1303672 13 Enhancerq22.3 101928753 101965616 23 Enhancerq24.31 122957417 122985518 10 Suppressorp21 43449541 43453748 1 Enhancerp25.1 15111580 15140670 10 Suppressorq11.2 30677136 30708905 18 Enhancerq12.2 32912176 32925446 6 Suppressor*q13.43 56700939 56709289 4 Suppressor

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Lejeune FX et al., 2012, BMC Genomics. 2012 Mar 13;13:91. doi: 10.1186/1471-2164-13-91.Zhang S et al., 2010, Genetics. 184, 1165-1246Branco J et al., 2008, Human Molecular Genetics 17, 376-394Lejeune FX et al., 2012, BMC Genomics. 2012 Mar 13;13:91. doi: 10.1186/1471-2164-13-91.Willingham S, 2003,Science 302, 1769 - 1804Zhang S et al., 2010, Genetics. 184, 1165-1235Doumanis J et al., 2009, PLoS One 4(9):e7286Lejeune FX et al., 2012, BMC Genomics. 2012 Mar 13;13:91. doi: 10.1186/1471-2164-13-91.Miller JP et al., 2012, PLOS Genetics, Nov;8(11):e1003042. doi: 10.1371/journal.pgen.1003042. Epub 2012 Nov 29.Zhang S et al., 2010, Genetics. 184, 1165-1274Zhang S et al., 2010, Genetics. 184, 1165-1268Zhang S et al., 2010, Genetics. 184, 1165-1252Miller JP et al., 2012, PLOS Genetics, Nov;8(11):e1003042. doi: 10.1371/journal.pgen.1003042. Epub 2012 Nov 29.Lejeune FX et al., 2012, BMC Genomics. 2012 Mar 13;13:91. doi: 10.1186/1471-2164-13-91.Zhang S et al., 2010, Genetics. 184, 1165-1194Zhang S et al., 2010, Genetics. 184, 1165-1267Lejeune FX et al., 2012, BMC Genomics. 2012 Mar 13;13:91. doi: 10.1186/1471-2164-13-91.Lejeune FX et al., 2012, BMC Genomics. 2012 Mar 13;13:91. doi: 10.1186/1471-2164-13-91.Lejeune FX et al., 2012, BMC Genomics. 2012 Mar 13;13:91. doi: 10.1186/1471-2164-13-91.Doumanis J et al., 2009, PLoS One 4(9):e7293Lejeune FX et al., 2012, BMC Genomics. 2012 Mar 13;13:91. doi: 10.1186/1471-2164-13-91.Miller JP et al., 2012, PLOS Genetics, Nov;8(11):e1003042. doi: 10.1371/journal.pgen.1003042. Epub 2012 Nov 29.Miller JP et al., 2012, PLOS Genetics, Nov;8(11):e1003042. doi: 10.1371/journal.pgen.1003042. Epub 2012 Nov 29.Miller JP et al., 2012, PLOS Genetics, Nov;8(11):e1003042. doi: 10.1371/journal.pgen.1003042. Epub 2012 Nov 29.Miller JP et al., 2012, PLOS Genetics, Nov;8(11):e1003042. doi: 10.1371/journal.pgen.1003042. Epub 2012 Nov 29.Lejeune FX et al., 2012, BMC Genomics. 2012 Mar 13;13:91. doi: 10.1186/1471-2164-13-91.Zhang S et al., 2010, Genetics. 184, 1165-1257Willingham S, 2003,Science 302, 1769 - 1803Miller JP et al., 2012, PLOS Genetics, Nov;8(11):e1003042. doi: 10.1371/journal.pgen.1003042. Epub 2012 Nov 29.Miller JP et al., 2012, PLOS Genetics, Nov;8(11):e1003042. doi: 10.1371/journal.pgen.1003042. Epub 2012 Nov 29.Lejeune FX et al., 2012, BMC Genomics. 2012 Mar 13;13:91. doi: 10.1186/1471-2164-13-91.Doumanis J et al., 2009, PLoS One 4(9):e7279Lejeune FX et al., 2012, BMC Genomics. 2012 Mar 13;13:91. doi: 10.1186/1471-2164-13-91.Lejeune FX et al., 2012, BMC Genomics. 2012 Mar 13;13:91. doi: 10.1186/1471-2164-13-91.Lejeune FX et al., 2012, BMC Genomics. 2012 Mar 13;13:91. doi: 10.1186/1471-2164-13-91.Miller JP et al., 2012, PLOS Genetics, Nov;8(11):e1003042. doi: 10.1371/journal.pgen.1003042. Epub 2012 Nov 29.Zhang S et al., 2010, Genetics. 184, 1165-1270Zhang S et al., 2010, Genetics. 184, 1165-1237Lejeune FX et al., 2012, BMC Genomics. 2012 Mar 13;13:91. doi: 10.1186/1471-2164-13-91.Lejeune FX et al., 2012, BMC Genomics. 2012 Mar 13;13:91. doi: 10.1186/1471-2164-13-91.Zhang S et al., 2010, Genetics. 184, 1165-1276Zhang S et al., 2010, Genetics. 184, 1165-1183Lejeune FX et al., 2012, BMC Genomics. 2012 Mar 13;13:91. doi: 10.1186/1471-2164-13-91.Lejeune FX et al., 2012, BMC Genomics. 2012 Mar 13;13:91. doi: 10.1186/1471-2164-13-91.PLOS Current 2011,August 12;3:RRN1269Zhang S et al., 2010, Genetics. 184, 1165-1238PLOS Current 2011,August 12;3:RRN1270

Zhang S et al., 2010, Genetics. 184, 1165-1275Branco J et al., 2008, Human Molecular Genetics 17, 376-392Branco J et al., 2008, Human Molecular Genetics 17, 376-393Lejeune FX et al., 2012, BMC Genomics. 2012 Mar 13;13:91. doi: 10.1186/1471-2164-13-91.Lejeune FX et al., 2012, BMC Genomics. 2012 Mar 13;13:91. doi: 10.1186/1471-2164-13-91.Miller JP et al., 2012, PLOS Genetics, Nov;8(11):e1003042. doi: 10.1371/journal.pgen.1003042. Epub 2012 Nov 29.Lejeune FX et al., 2012, BMC Genomics. 2012 Mar 13;13:91. doi: 10.1186/1471-2164-13-91.Lejeune FX et al., 2012, BMC Genomics. 2012 Mar 13;13:91. doi: 10.1186/1471-2164-13-91.Zhang S et al., 2010, Genetics. 184, 1165-1255Zhang S et al., 2010, Genetics. 184, 1165-1256Doumanis J et al., 2009, PLoS One 4(9):e7280Lejeune FX et al., 2012, BMC Genomics. 2012 Mar 13;13:91. doi: 10.1186/1471-2164-13-91.Miller JP et al., 2012, PLOS Genetics, Nov;8(11):e1003042. doi: 10.1371/journal.pgen.1003042. Epub 2012 Nov 29.Miller JP et al., 2012, PLOS Genetics, Nov;8(11):e1003042. doi: 10.1371/journal.pgen.1003042. Epub 2012 Nov 29.Willingham S, 2003,Science 302, 1769 - 1805PLOS Current 2011,August 12;3:RRN1271Miller JP et al., 2012, PLOS Genetics, Nov;8(11):e1003042. doi: 10.1371/journal.pgen.1003042. Epub 2012 Nov 29.Lejeune FX et al., 2012, BMC Genomics. 2012 Mar 13;13:91. doi: 10.1186/1471-2164-13-91.Zhang S et al., 2010, Genetics. 184, 1165-1239Lejeune FX et al., 2012, BMC Genomics. 2012 Mar 13;13:91. doi: 10.1186/1471-2164-13-91.Lejeune FX et al., 2012, BMC Genomics. 2012 Mar 13;13:91. doi: 10.1186/1471-2164-13-91.Lejeune FX et al., 2012, BMC Genomics. 2012 Mar 13;13:91. doi: 10.1186/1471-2164-13-91.Zhang S et al., 2010, Genetics. 184, 1165-1240Lejeune FX et al., 2012, BMC Genomics. 2012 Mar 13;13:91. doi: 10.1186/1471-2164-13-91.Zhang S et al., 2010, Genetics. 184, 1165-1212Lejeune FX et al., 2012, BMC Genomics. 2012 Mar 13;13:91. doi: 10.1186/1471-2164-13-91.Zhang S et al., 2010, Genetics. 184, 1165-1197Branco J et al., 2008, Human Molecular Genetics 17, 376-400Lejeune FX et al., 2012, BMC Genomics. 2012 Mar 13;13:91. doi: 10.1186/1471-2164-13-91.Lejeune FX et al., 2012, BMC Genomics. 2012 Mar 13;13:91. doi: 10.1186/1471-2164-13-91.Lejeune FX et al., 2012, BMC Genomics. 2012 Mar 13;13:91. doi: 10.1186/1471-2164-13-91.Lejeune FX et al., 2012, BMC Genomics. 2012 Mar 13;13:91. doi: 10.1186/1471-2164-13-91.Miller JP et al., 2012, PLOS Genetics, Nov;8(11):e1003042. doi: 10.1371/journal.pgen.1003042. Epub 2012 Nov 29.Lejeune FX et al., 2012, BMC Genomics. 2012 Mar 13;13:91. doi: 10.1186/1471-2164-13-91.

Miller JP et al., 2012, PLOS Genetics, Nov;8(11):e1003042. doi: 10.1371/journal.pgen.1003042. Epub 2012 Nov 29.

Miller JP et al., 2012, PLOS Genetics, Nov;8(11):e1003042. doi: 10.1371/journal.pgen.1003042. Epub 2012 Nov 29.Miller JP et al., 2012, PLOS Genetics, Nov;8(11):e1003042. doi: 10.1371/journal.pgen.1003042. Epub 2012 Nov 29.Miller JP et al., 2012, PLOS Genetics, Nov;8(11):e1003042. doi: 10.1371/journal.pgen.1003042. Epub 2012 Nov 29.


Miller JP et al., 2012, PLOS Genetics, Nov;8(11):e1003042. doi: 10.1371/journal.pgen.1003042. Epub 2012 Nov 29.Miller JP et al., 2012, PLOS Genetics, Nov;8(11):e1003042. doi: 10.1371/journal.pgen.1003042. Epub 2012 Nov 29.







Miller JP et al., 2012, PLOS Genetics, Nov;8(11):e1003042. doi: 10.1371/journal.pgen.1003042. Epub 2012 Nov 29.Miller JP et al., 2012, PLOS Genetics, Nov;8(11):e1003042. doi: 10.1371/journal.pgen.1003042. Epub 2012 Nov 29.Miller JP et al., 2012, PLOS Genetics, Nov;8(11):e1003042. doi: 10.1371/journal.pgen.1003042. Epub 2012 Nov 29.Miller JP et al., 2012, PLOS Genetics, Nov;8(11):e1003042. doi: 10.1371/journal.pgen.1003042. Epub 2012 Nov 29.




Miller JP et al., 2012, PLOS Genetics, Nov;8(11):e1003042. doi: 10.1371/journal.pgen.1003042. Epub 2012 Nov 29.Miller JP et al., 2012, PLOS Genetics, Nov;8(11):e1003042. doi: 10.1371/journal.pgen.1003042. Epub 2012 Nov 29.Miller JP et al., 2012, PLOS Genetics, Nov;8(11):e1003042. doi: 10.1371/journal.pgen.1003042. Epub 2012 Nov 29.Miller JP et al., 2012, PLOS Genetics, Nov;8(11):e1003042. doi: 10.1371/journal.pgen.1003042. Epub 2012 Nov 29.Miller JP et al., 2012, PLOS Genetics, Nov;8(11):e1003042. doi: 10.1371/journal.pgen.1003042. Epub 2012 Nov 29.






Supplementary Table 3: Co-expression of genes with Wild type HTT (http://coxpresdb.jp) Gene Function

556 ABCC10 ATP-binding cassette, sub-family C (CFTR/MRP), member 10734 ABR active BCR-related

30 ACOX3 acyl-CoA oxidase 3, pristanoyl576 ADAR adenosine deaminase, RNA-specific

37 ADD1 adducin 1 (alpha)711 AGPAT6 1-acylglycerol-3-phosphate O-acyltransferase 6 (lysophosphatidic acid acylt498 AMBRA1 autophagy/beclin-1 regulator 1261 ANKRD11 ankyrin repeat domain 11

80 ANKRD52 ankyrin repeat domain 5225 AP1B1 adaptor-related protein complex 1, beta 1 subunit

428 AP1G2 adaptor-related protein complex 1, gamma 2 subunit101 AP2A2 adaptor-related protein complex 2, alpha 2 subunit

87 AP3D1 adaptor-related protein complex 3, delta 1 subunit154 ARFGAP2 ADP-ribosylation factor GTPase activating protein 2724 ARID3B AT rich interactive domain 3B (BRIGHT-like)604 ASB1 ankyrin repeat and SOCS box containing 1687 ASXL1 additional sex combs like 1 (Drosophila)

54 ATP13A1 ATPase type 13A1446 ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1

55 BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)332 BRD9 bromodomain containing 9166 BRPF1 bromodomain and PHD finger containing, 1225 BTBD9 BTB (POZ) domain containing 9478 C10orf76 chromosome 10 open reading frame 76454 CABIN1 calcineurin binding protein 1100 CABLES1 Cdk5 and Abl enzyme substrate 1202 CC2D1B coiled-coil and C2 domain containing 1B741 CEP250 centrosomal protein 250kDa

73 CHD3 chromodomain helicase DNA binding protein 3152 CHD4 chromodomain helicase DNA binding protein 4176 CHD8 chromodomain helicase DNA binding protein 8169 CLCN6 chloride channel, voltage-sensitive 6264 CLEC16A C-type lectin domain family 16, member A233 CNNM4 cyclin M4725 COG7 component of oligomeric golgi complex 7524 CREBBP CREB binding protein

46 CRIPAK cysteine-rich PAK1 inhibitor248 CUL9 cullin 9726 CYFIP2 cytoplasmic FMR1 interacting protein 2521 DCTN1 dynactin 1637 DDB1 damage-specific DNA binding protein 1, 127kDa700 DDX23 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23437 DENND4B DENN/MADD domain containing 4B

206 DEPDC5 DEP domain containing 5435 DGCR8 DiGeorge syndrome critical region gene 8198 DGKD diacylglycerol kinase, delta 130kDa

50 DHX30 DEAH (Asp-Glu-Ala-His) box polypeptide 30230 DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38

93 DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8677 DIAPH1 diaphanous homolog 1 (Drosophila)710 DIDO1 death inducer-obliterator 1569 DIS3L2 DIS3 mitotic control homolog (S. cerevisiae)-like 2616 DNHD1 dynein heavy chain domain 1581 DNM2 dynamin 2259 DOT1L DOT1-like, histone H3 methyltransferase (S. cerevisiae)384 DPP9 dipeptidyl-peptidase 9201 DYNC1H1 dynein, cytoplasmic 1, heavy chain 1381 EDC3 enhancer of mRNA decapping 3 homolog (S. cerevisiae)

5 EDC4 enhancer of mRNA decapping 4685 EEF2K eukaryotic elongation factor-2 kinase

95 EFTUD2 elongation factor Tu GTP binding domain containing 2208 ELAC2 elaC homolog 2 (E. coli)262 EP400 E1A binding protein p400172 EXOC3 exocyst complex component 3171 EXOC7 exocyst complex component 7192 EZH1 enhancer of zeste homolog 1 (Drosophila)

2 FAM193A family with sequence similarity 193, member A535 FAM40A family with sequence similarity 40, member A572 FBXO42 F-box protein 42441 FLII flightless I homolog (Drosophila)328 FLNB filamin B, beta321 FTSJD2 FtsJ methyltransferase domain containing 2

1 GAK cyclin G associated kinase467 GATAD2B GATA zinc finger domain containing 2B439 GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1118 GCN1L1 GCN1 general control of amino-acid synthesis 1-like 1 (yeast)436 GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3642 GOLGA1 golgin A1701 GOLGA3 golgin A3447 GOLGB1 golgin B1590 GON4L gon-4-like (C. elegans)540 GRIPAP1 GRIP1 associated protein 1

6 GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa703 HCFC1 host cell factor C1 (VP16-accessory protein)420 HDAC6 histone deacetylase 6128 HECTD4 HECT domain containing E3 ubiquitin protein ligase 4110 HGSNAT heparan-alpha-glucosaminide N-acetyltransferase350 HMGXB3 HMG box domain containing 3

0 HTT huntingtin94 HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase96 ILF3 interleukin enhancer binding factor 3, 90kDa44 INPPL1 inositol polyphosphate phosphatase-like 118 INTS1 integrator complex subunit 197 IQSEC1 IQ motif and Sec7 domain 1

235 KCTD2 potassium channel tetramerisation domain containing 2490 KIAA0100 KIAA0100459 KIAA0195 KIAA0195414 KIAA0319LKIAA0319-like109 KIAA0556 KIAA0556148 KIAA0922 KIAA0922739 LDB1 LIM domain binding 1

77 LETM1 leucine zipper-EF-hand containing transmembrane protein 1730 LPCAT1 lysophosphatidylcholine acyltransferase 1

34 MADD MAP-kinase activating death domain20 MAEA macrophage erythroblast attacher

388 MAP4 microtubule-associated protein 4691 MAPKBP1 mitogen-activated protein kinase binding protein 1250 MAVS mitochondrial antiviral signaling protein486 MCM3AP minichromosome maintenance complex component 3 associated protein

66 MECP2 methyl CpG binding protein 2 (Rett syndrome)75 MED15 mediator complex subunit 15

530 MED24 mediator complex subunit 24699 MFN2 mitofusin 2274 MLL/KMT2lysine (K)-specific methyltransferase 2A189 MLL2/KMTlysine (K)-specific methyltransferase 2D276 MLL4/KMTlysine (K)-specific methyltransferase 2B228 MTOR mechanistic target of rapamycin (serine/threonine kinase)450 MYH9 myosin, heavy chain 9, non-muscle142 MYO9B myosin IXB404 NBEAL2 neurobeachin-like 2671 NCOR2 nuclear receptor corepressor 2481 NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2565 NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3

8 NISCH nischarin484 NOD1 nucleotide-binding oligomerization domain containing 1131 NOP14 NOP14 nucleolar protein homolog (yeast)

31 NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae)98 NUMA1 nuclear mitotic apparatus protein 184 NUP188 nucleoporin 188kDa

593 PAN2 PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)218 PCGF3 polycomb group ring finger 3657 PCNT pericentrin628 PCNXL3 pecanex-like 3 (Drosophila)

309 PCSK7 proprotein convertase subtilisin/kexin type 7665 PDCD11 programmed cell death 11122 PI4KA phosphatidylinositol 4-kinase, catalytic, alpha158 PI4KB phosphatidylinositol 4-kinase, catalytic, beta709 PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta334 PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta638 PKD1 polycystic kidney disease 1 (autosomal dominant)

14 PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) mem212 POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa550 POLR3A polymerase (RNA) III (DNA directed) polypeptide A, 155kDa

88 POMT2 protein-O-mannosyltransferase 2654 PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2613 PPP1R13B protein phosphatase 1, regulatory subunit 13B

61 PPP6R1 protein phosphatase 6, regulatory subunit 1403 PPP6R2 protein phosphatase 6, regulatory subunit 2

48 PRPF8 PRP8 pre-mRNA processing factor 8 homolog (S. cerevisiae)135 PRRC2A proline-rich coiled-coil 2A

11 PRRC2B proline-rich coiled-coil 2B91 RAD54L2 RAD54-like 2 (S. cerevisiae)

364 RANBP10 RAN binding protein 10684 RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1466 RBM19 RNA binding motif protein 19529 RBM5 RNA binding motif protein 5584 RECQL5 RecQ protein-like 5

7 RNF4 ring finger protein 436 RNF40 ring finger protein 40, E3 ubiquitin protein ligase

487 RPAP1 RNA polymerase II associated protein 1329 RPTOR regulatory associated protein of MTOR, complex 1413 SBF1 SET binding factor 1215 SEC16A SEC16 homolog A (S. cerevisiae)

52 SEC24C SEC24 family, member C (S. cerevisiae)655 SF3B2 splicing factor 3b, subunit 2, 145kDa246 SFI1 Sfi1 homolog, spindle assembly associated (yeast)245 SFSWAP splicing factor, suppressor of white-apricot homolog (Drosophila)

33 SGSM2 small G protein signaling modulator 2354 SHPK sedoheptulokinase291 SIN3B SIN3 transcription regulator homolog B (yeast)224 SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromati716 SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromati144 SMG5 smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans)

81 SMG6 smg-6 homolog, nonsense mediated mRNA decay factor (C. elegans)227 SNRNP200small nuclear ribonucleoprotein 200kDa (U5)

76 SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive)323 SPTAN1 spectrin, alpha, non-erythrocytic 1373 SRRM2 serine/arginine repetitive matrix 2

366 SUGP2 SURP and G patch domain containing 2124 SUPT5H suppressor of Ty 5 homolog (S. cerevisiae)108 SUPT6H suppressor of Ty 6 homolog (S. cerevisiae)640 SYMPK symplekin

74 SZT2 seizure threshold 2 homolog (mouse)727 TATDN2 TatD DNase domain containing 2140 TBC1D13 TBC1 domain family, member 13102 TBC1D14 TBC1 domain family, member 14

13 TBC1D22ATBC1 domain family, member 22A283 TBC1D9B TBC1 domain family, member 9B (with GRAM domain)614 TBCD tubulin folding cofactor D383 TCF25 transcription factor 25 (basic helix-loop-helix)545 TECPR2 tectonin beta-propeller repeat containing 2475 TOM1L2 target of myb1-like 2 (chicken)470 TOP3B topoisomerase (DNA) III beta630 TRAK1 trafficking protein, kinesin binding 1639 TRAPPC9 trafficking protein particle complex 9149 TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associa247 TSC1 tuberous sclerosis 1429 TSC2 tuberous sclerosis 2714 TTC17 tetratricopeptide repeat domain 17

56 TUBGCP2 tubulin, gamma complex associated protein 2318 TYK2 tyrosine kinase 2615 UBA1 ubiquitin-like modifier activating enzyme 1162 UBAP2L ubiquitin associated protein 2-like130 UBR4 ubiquitin protein ligase E3 component n-recognin 4

82 UPF1 UPF1 regulator of nonsense transcripts homolog (yeast)68 USP19 ubiquitin specific peptidase 1964 USP20 ubiquitin specific peptidase 20

650 USP22 ubiquitin specific peptidase 22378 USP40 ubiquitin specific peptidase 40492 USP7 ubiquitin specific peptidase 7 (herpes virus-associated)505 VAC14 Vac14 homolog (S. cerevisiae)120 VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae)160 VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)194 VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)480 WDR59 WD repeat domain 59319 WDR6 WD repeat domain 6448 WHSC1 Wolf-Hirschhorn syndrome candidate 1624 XPC xeroderma pigmentosum, complementation group C

26 XPO6 exportin 6551 YY1AP1 YY1 associated protein 1

28 ZBTB40 zinc finger and BTB domain containing 40317 ZFYVE27 zinc finger, FYVE domain containing 27715 ZMIZ2 zinc finger, MIZ-type containing 2

358 ZMYM3 zinc finger, MYM-type 3137 ZNF142 zinc finger protein 142664 ZNF589 zinc finger protein 589324 ZNF592 zinc finger protein 592340 ZNF76 zinc finger protein 76210 ZNF767 zinc finger family member 767213 ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

Entrez Gene ID Chromosome Band Reliability Hsa MR Hsa1 MR Mcc Mmu (MouRno (Rat)89845 6 p21.1 ☆☆ 766.8 785.8 2978.3 11376.7 4180.5

29 17 p13.3 ☆☆ 988.6 207 6955.1 4258.98310 4 p16.1 ☆☆ 73.9 39.8 526.3 6433.4 4289.1

103 1 q21.3 ☆☆☆ 793 172.8 23 4495.7118 4 p16.3 ☆☆☆ 86.1 8.1 6030 7476.7 5338

137964 8 p11.21 ☆ 972 277.2 8242.9 9744.555626 11 p11.2 ☆ 701.2 121.8 11824.1 135.5 5617.129123 16 q24.3 ☆☆ 415.9 352.6 5452.1 199.7

283373 12 q13.3 ☆☆ 164.5 111.2 947.9 1772.6162 22 q12.2 ☆☆☆ 64.9 117.9 483.5 1325.6 1902.6

8906 14 q11.2 ☆☆☆ 624.5 322.7 2196.9 1304.8161 11 p15.5 ☆☆☆ 210.1 156.3 69.9 49.1 5495.7

8943 19 p13.3 ☆ 183.2 58.4 186.9 5810.584364 11 p11.2 ☆☆ 278.6 703 1098.5 6634.8 601510620 15 q24.1 ☆☆ 984.5 813.9 2248.9 5679.1 1761.851665 2 q37.3 833 923.9 5143.7 4450.9 3548.6

171023 20 q11.21 ☆☆ 941.8 326.7 843.1 2288.4 3348.857130 19 p13.11 ☆☆☆ 110.4 499.5 736.8 5520.1

535 17 q21.2 ☆☆ 645.6 125.5 5735.1 5616.48314 3 p21.1 ☆☆ 114.4 547.3 288.6 3667.1 7659.9

65980 5 p15.33 ☆☆ 495.8 604.9 10088.6 10256.97862 3 p25.3 ☆☆ 295.2 390.6 1210.9 1556.7 11608.4

114781 6 p21.2 370.5 624.4 3034.5 500.6 13606.279591 10 q24.32 683 92 2565.4 3901.7 1343.123523 22 q11.23 ☆☆ 656.1 40 1483.5 1580.691768 18 q11.2 ☆ 209.3 425 14479.4 7309.5

200014 1 p32.3 ☆☆ 343 857.9 4073 4155.9 6482.711190 20 q11.22 ☆☆ 997.1 407.2 2105.9 9107.2 6559.2

1107 17 p13.1 ☆☆☆ 152.9 310.5 4532.8 11132.81108 12 p13.31 ☆☆☆ 277.5 35.5 3819.3 4046.5

57680 14 q11.2 ☆☆ 308.5 9.2 3406.2 82.8 4646.81185 1 p36.22 ☆☆☆ 296.4 72.3 5792.9 485

23274 16 p13.13 ☆☆ 420.9 45.5 1381.4 8596.7 7119.126504 2 q11.2 ☆☆ 377.2 552.1 10518.891949 16 p12.2 ☆☆ 984.8 382.4 2562.6 10845.5 9956.6

1387 16 p13.3 ☆☆ 730 186.7 12381.7 3044.8 4911.2285464 4 p16.3 ☆☆ 100.5 448

23113 6 p21.1 ☆☆ 399.7 109.5 3758.4 8718 247226999 5 q33.3 ☆☆☆ 984.9 192.5 2332.9 7131.5

1639 2 p13.1 ☆☆☆ 726.2 134.1 1073.7 3520.3 80711642 11 q12.2 ☆☆☆ 882.3 209 1478.9 1406.49416 12 q13.12 ☆☆☆ 962.5 840.5 4533.9 471.7 7639.19909 1 q21.3 ☆☆ 633.5 926.4 7597.3 1598.8 1331.6

9681 22 q12.2 ☆☆ 346.1 87.3 724.7 5420.154487 22 q11.21 ☆☆ 633.3 395.5 2409.8 4417.8

8527 2 q37.1 ☆☆ 338.8 278.8 10529.3 178122907 3 p21.31 ☆☆☆ 107.4 555.4 954.2 155.2 7712.6

9785 16 q22.2 ☆☆ 375 270.6 1663.3 1913.1 10493.71659 17 q21.31 ☆☆☆ 197.2 384.2 7384.7 2242.2 6163.21729 5 q31.3 ☆ 929.9 128.7 13791.4 929.2 4326.3

11083 20 q13.33 971.9 55.3 8914.5 18129563 2 q37.1 ☆ 789.7 144.2 71.4 6360.6144132 11 p15.4 ☆☆ 851.2 419.3

1785 19 p13.2 ☆☆☆ 797.9 270.6 2576.9 5063.4 182384444 19 p13.3 ☆☆☆ 413.9 945.9 785.9 934.9 6680.591039 19 p13.3 ☆☆ 559.6 409.5 860.9 2552

1778 14 q32.31 ☆☆☆ 342.1 6.5 11623.8 662.9 4919.780153 15 q24.1 ☆☆ 553.7 717.9 3581.4 789023644 16 q22.1 ☆☆☆ 21.8 203.2 984.3 10878.229904 16 p12.2 939.3 591.8 10414.1 6603.2

9343 17 q21.31 ☆☆☆ 198.2 763.2 2164.6 3004.3 907.360528 17 p12 ☆☆☆ 349.4 556.3 1942 10320.157634 12 q24.33 ☆☆ 418.2 16.2 4160.2 1805.6 678611336 5 p15.33 ☆☆ 305.1 690.7 1124.5 3232.5 8771.823265 17 q25.1 ☆☆ 297.4 365.3 9309.1 2108.7

2145 17 q21.2 ☆☆☆ 333.9 762.2 2726.2 7628.4 3304.68603 4 p16.3 ☆☆ 8.6 21 6283.6 1800.4

85369 1 p13.3 ☆☆ 739.4 187.3 1250.5 9206.154455 1 p36.13 ☆☆ 791.8 282.5 1496.1 558.7 3855.8

2314 17 p11.2 ☆☆ 635.9 711.5 7390.1 8011.42317 3 p14.3 ☆☆☆ 484.9 405.6 10284.3 204.2 2287.2

23070 4 p16.3 ☆☆☆ 480 102.9 5744.6 2497.2 7206.92580 1 q21.3 ☆☆☆ 2.5 61.2 679.5 5458.5 5890.5

57459 1 q21.3 ☆☆ 671.1 402 1641.2 7941.48729 10 q24.32 ☆☆ 635.1 11.8 1162.2 1127.4 1899.2

10985 12 q24.23 ☆☆☆ 237.6 40.4 733.5 586.8 1277.523163 17 q25.1 ☆☆ 633.5 265.7 2001.9 1435.6

2800 9 q33.3 ☆☆☆ 888.5 517.7 9781 975.52802 12 q24.33 ☆☆ 964.3 266.8 2223.2 9901.62804 3 q13.33 ☆☆☆ 647.6 675.5 9950.4 4602.5 8677.8

54856 1 q22 ☆☆☆ 812.8 143.2 5362.2 2981.956850 X p11.23 ☆☆ 744.2 243.2 4082.4 10683.2

2975 16 p12.1 ☆☆☆ 23.4 12.7 223.9 3485.8 5682.63054 X q28 ☆☆ 968 131.6 3645.3 5449.3

10013 X p11.23 ☆☆☆ 612.7 343.7 7678.8 4511.4283450 12 q24.13 ☆☆☆ 247.2 13.8 4774.8 4039.1 5186.2138050 8 p11.21 ☆☆ 225.8 943 13790.8

22993 5 q32 ☆ 509.1 197.7 864.5 45.2

3064 4 p16.3 ☆☆ 0 0 0 0 010075 X p11.22 ☆☆☆ 197.3 2.5 1949.7 633.4

3609 19 p13.2 ☆☆ 202 541.9 847.9 8062.33636 11 q13.4 ☆☆☆ 96.1 420 3020.4 7625.8 2601.4

26173 7 p22.3 ☆☆☆ 53.2 887.5 57.9 6359922 3 p25.2 ☆☆ 207.6 380 2905.9 8361.7

23510 17 q25.1 ☆☆ 380.3 834.9 11802.19703 17 q11.2 ☆☆☆ 698.3 13.5 1142.5 1430.4 6087.49772 17 q25.1 ☆ 664.8 235.2 302.3 10792.6

79932 1 p34.3 ☆ 601.3 22.3 5007.223247 16 p12.1 ☆☆☆ 224.9 333.1 926 11785.5 10010.323240 4 q31.3 ☆☆ 271.2 52 2820.9 1216.5 4422.4

8861 10 q24.32 ☆ 993.9 476.8 6205.4 11960.6 12108.43954 4 p16.3 ☆☆☆ 156.2 656.7 6628.5 8831.5

79888 5 p15.33 ☆☆ 986.6 413.1 2731.9 3074.6 3773.88567 11 p11.2 ☆☆ 82.4 19.7 393.1 717.5 3494.5

10296 4 p16.3 ☆☆ 60.1 984.1 4277.6 88994134 3 p21.31 ☆ 564 73.5 3525 696.9

23005 15 q15.1 948.9 584.9 6787.8 5505.957506 20 p13 ☆ 402 416.4 7340.4 5131.8

8888 21 q22.3 ☆☆ 693.3 26.1 5880.2 2549.3 1129.14204 X q28 ☆☆☆ 139 591 564.2 1983.9

51586 22 q11.21 ☆☆ 155.7 959.8 346.6 10.7 120019862 17 q21.1 ☆☆☆ 737.2 216.4 2730.7 4006.29927 1 p36.22 ☆☆ 962.1 644.7 6842.5 8290.24297 11 q23 ☆☆☆ 432.2 50 4660.4 671.3 3541.28085 12 q13.12 ☆☆☆ 330 84.3 2968.5 11378.19757 19 q13.1 ☆☆☆ 436.6 616.5 2514.6 1975.4 4240.42475 1 p36.22 ☆☆ 373.6 4.2 3789.1 63974627 22 q12.3 ☆☆☆ 653.1 615.5 510.8 4126.24650 19 p13.11 ☆☆☆ 259.8 129.6 865.2 29.3 5630

23218 3 p21.31 ☆☆☆ 589.2 722.2 46129612 12 q24.31 ☆☆ 923.3 529.4 2162.6 4446.8 1980.68509 10 q22.2 686.6 159.2 4988.1 4569.7 2724

23327 18 q21.31 ☆☆ 782.3 809.8 2422.1 496.1 11051.211188 3 p21.1 ☆☆☆ 30.9 188.4 203.7 4211.810392 7 p14.3 ☆☆ 688.9 682 14362.9 11284.6 12007.6

8602 4 p16.3 ☆☆☆ 248.2 403.8 3015.5 447755666 17 q25.3 ☆☆ 73.9 210.7 937.1 5294.3 5429.9

4926 11 q13.4 ☆☆ 207.6 137.4 3150.6 2427.2 5097.423511 9 q34.11 ☆☆ 172.8 191.2 1693.9 936.9 1034.5

9924 12 q13.3 ☆☆☆ 814.3 369.3 12351.3 4301.4 986.610336 4 p16.3 ☆ 362 464.6 5136.6

5116 21 q22.3 ☆☆ 904.8 332.3 5752.3399909 11 q13.1 ☆☆ 869.5 400.1 3528.2 2500.3 2293.2

9159 11 q23.3 ☆ 466.7 479.7 9057.3 3219.8 8615.522984 10 q24.33 ☆☆☆ 915.2 859.8 2342.6 1021.8 7336.4

5297 22 q11.21 ☆☆☆ 244.3 43.1 1009 1427.6 8412.15298 1 q21.3 ☆☆ 284.8 425.1 4509.6 327.2 7072.35287 1 q32.1 ☆☆ 971.6 141.6 6621.8 3084.48396 17 q12 ☆☆ 497.7 255.9 2987.9 1910.25310 16 p13.3 ☆☆ 884.7 821.7 3521.7 5847.9 6522.6

23207 1 p36.21 ☆☆☆ 45.7 734 2641.5 3910.25430 17 p13.1 ☆☆☆ 354.8 63.4 2302.1 4519.2 11127.8

11128 10 q22.3 ☆☆☆ 762.2 88.2 1146.7 2004.829954 14 q24.3 188 777.1 2987.6 4541.423759 22 q11.21 ☆ 898.2 116 12338.6 12289.423368 14 q32.33 ☆ 847.9 660.1 7403.4 7461.9 8816.722870 19 q13.42 ☆☆☆ 126.1 387.8 3609.6 1067.6

9701 22 q13.33 ☆ 588.7 281.3 3630.3 10331.2 730.410594 17 p13.3 ☆☆☆ 101.5 16.2 4253.3 1949.9 935.9

7916 6 p21.33 ☆☆ 253.7 304 464.4 5049.4 3910.584726 9 q34.13 ☆☆☆ 39.6 25.5 4088.423132 3 p21.2 ☆☆ 192.1 13.8 5149.2 5509 826.457610 16 q22.1 ☆☆☆ 525.4 710.4 3190.6 2132.7 11218.3

2889 9 q34.13 ☆☆ 939.3 70.5 394.4 7861.89904 12 q24.21 ☆☆☆ 669.6 402.2 825.5 1323.8 2904.6

10181 3 p21.31 ☆☆☆ 736.5 502.5 6505.8 631.8 9267.29400 17 q25.1 ☆ 801.8 782.3 1478.2 1287.3 319.96047 4 p16.3 ☆☆☆ 26.8 298.6 6766.9 61169810 16 p11.2 ☆☆ 83.6 582 2340.9 2369.3 1577.3

26015 15 q15.1 ☆☆☆ 694 862.2 162.6 8543.657521 17 q25.3 ☆☆ 488.4 55.8 2264 1448.5 4438.1

6305 22 q13.33 ☆☆ 600.9 862.3 2646.3 1535.49919 9 q34.3 ☆☆☆ 358 38.4 2979.29632 10 q22.2 ☆☆☆ 109 41.1 713.1 6784.3

10992 11 q13.1 ☆☆ 898.3 669.8 2389.8 3695.39814 22 q12.2 ☆☆☆ 395.2 741.5 3486.3 390.6 9818.36433 12 q24.33 ☆☆☆ 392.5 350.2 7494.7 273.9 2905.89905 17 p13.3 ☆☆☆ 79.2 631.3 4493.7 8364.4

23729 17 p13.2 ☆☆☆ 512.2 548.6 14988.1 12607.123309 19 p13.11 ☆☆☆ 452.8 324.9 235.7 8652.6

6601 12 q13.2 ☆☆ 369.8 266.7 10718.7 603.56602 12 q13.12 ☆☆ 974.3 349.8 1209 9305.8 1986

23381 1 q22 ☆☆ 262.2 292.4 1644.4 468 4739.323293 17 p13.3 ☆☆ 164.6 34.6 2126.3 1381.8 1949.423020 2 q11.2 ☆☆☆ 373.2 18.5 8436.2 1865.3 7476.9

6687 16 q24.3 ☆☆☆ 156.1 44.7 1948.8 8084.9 5685.86709 9 q34.11 ☆☆ 480.3 24.8 4868.2 6455.1 7331.2

23524 16 p13.3 ☆☆ 540 56.9 396.6

10147 19 p13.11 ☆☆☆ 531.8 79.9 4439.5 7882.26829 19 q13.2 ☆☆☆ 244.9 608.8 1468.4 19006830 17 q11.2 ☆☆ 224 32.9 1020.7 2170.6 7215.78189 19 q13.32 ☆☆ 887 250.8 856.7 7850.1

23334 1 p34.2 ☆☆☆ 155.5 117.9 4205.1 1850.3 1283.29797 3 p25.3 ☆☆ 985.5 224.8 4038 11023.5

54662 9 q34.11 ☆☆☆ 257.7 905.7 653 2373.557533 4 p16.1 ☆☆ 211.1 120.9 4809.1 10727.7 12508.925771 22 q13.31 ☆☆ 44.2 72.8 1742.7 7228.323061 5 q35.3 ☆☆ 439.9 272 1259 1283.3

6904 17 q25.3 ☆☆ 847.9 153 1347.7 1410.522980 16 q24.3 ☆ 557.6 711 3316.3 378.1 8549

9895 14 q32.31 ☆ 750.4 857.9 553.7 4646.5146691 17 p11.2 ☆ 679 662.6 5710.4 5606.6 2416.9

8940 22 q11.22 ☆☆ 672.6 533.1 720.4 4087.9 2165.122906 3 p22.1 ☆☆ 869.9 86.8 11453 3950.2 13443.883696 8 q24.3 ☆ 886.1 82.8 1208.2 4362.426133 20 q11.22 ☆☆ 273.5 303.1 8127.4 2269.9

7248 9 q34.13 ☆☆☆ 396.4 124.3 7386.2 516.8 4852.27249 16 p13.3 ☆☆☆ 624.5 316 3594.3 7771.1 5450

55761 11 p12 ☆☆ 973.4 578.4 7578.9 13863.2 1040510844 10 q26.3 ☆☆ 117.1 528 252 8370.8 3074.3

7297 19 p13.2 ☆☆☆ 476.3 844.9 5749.4 695.47317 X p11.23 ☆☆☆ 848.1 72.1 1906.8 1867.3 4383.49898 1 q21.3 ☆☆ 288.5 225.9 3581.2 957.7

23352 1 p36.13 ☆☆☆ 247.7 4.5 3397.4 1104.8 6835.85976 19 p13.11 ☆☆ 169.2 747.4 3812.5

10869 3 p21.31 ☆☆ 142.5 418.9 251.4 1235.2 1774.510868 9 q34.11 ☆☆☆ 133.4 958 1293.5 5177.7 1557.823326 17 p11.2 ☆ 895.1 60.3 1091155230 2 q37.1 ☆ 547.9 951.5 263.5 1233.1

7874 16 p13.2 ☆☆ 699.5 551.9 98.4 729655697 16 q22.2 ☆☆ 708 170.4 441 2539.7 669.855823 11 q23.3 ☆☆ 242 757.1 7813.6 10451.455187 1 p36.22 ☆☆☆ 287.1 16.4 1168.8 2791.123339 15 q15.1 ☆☆ 334.5 75.7 3324.2 7352 9275.979726 16 q23.1 ☆☆☆ 684.6 36.2 5483.6 629.111180 3 p21.31 ☆☆ 476.9 347.5 3502.4 14368.3 9655.7

7468 4 p16.3 ☆☆☆ 649.5 412.2 1952.8 1198.5 3224.97508 3 p25.1 ☆☆☆ 864.2 873.1 15323.9 5580.4

23214 16 p11.2 ☆☆ 66 560.3 267.6 1340.8 8951.555249 1 q22 ☆☆ 763.1 845.8 3053.6

9923 1 p36.12 ☆☆ 68.4 36.1 10137.4118813 10 q24.2 ☆☆☆ 474.2 927.9 2810.5 7593.4 3056.9

83637 7 p13 ☆☆ 974 790.9 304.4 2081.2 5435.2

9203 X q13.1 ☆☆☆ 517.3 87.5 516.1 8732.5 2630.97701 2 q35 ☆☆ 255 424.7 3378 2551.3 2612.7

51385 3 p21.31 914.9 416.5 14036.19640 15 q25.3 ☆☆ 481.1 521.8 3249.4 1749.3 1874.27629 6 p21.31 ☆☆ 505.4 818.9 1072.6 1158.1

79970 7 q36.1 ☆☆☆ 352.8 798.423140 17 p13.2 ☆☆ 355.8 19.5 4462.4 141.5 2829.3

Cfa (dog) Gga (ChikeDre (ZebrafTotal9131.7 5593.2 21510.1 4693 2

516.7 1640 37839 1046 3

1570.3 6086.8 2353.4 27117 1837.7 3316.9 25363 806.6 4

6011.7 7412.8 34088.8 2882.9 3

14309.4 4670.6 334.8 41029 2

10838.6 4781.3 1905.8 411930.8 925.5 4

2568.7 3467.5 2117 23901.9 7738.9 2

12079.6 8063.7 24317.3 3

11774.5 8292.5 4657.3 36939.2 5889.8 2

10478.5 1505.7 34145.8 4581.4 2

7264.4 4657.6 5758.4 213315.7 372.4 1500.8 513791.1 761.5 3

3483.6 2341 29239.5 2

15561.6 2950.4 4301.8 23688.8 2160.4 7522.4 21559.7 24661.5 226.3 1923.3 3

4465 32364.9 3

229.5 250.4 49027 2

14669.2 4152.7 5070.6 25135.6 8710.5 1273 2

22639.8 5323.3 24838.8 7336.5 27165.1 2

15956.7 4126.2 710.5 314388.4 7949 3

7108.2 2

3478.5 1856.8 5715.5 37320.2 264.6 78.6 4

10313.3 3359.2 213295 5754.4 4

13109.4 10126.9 214929.5 403.8 3

1160 387.1 3

10260.4 1259.8 31653.6 28465.6 21753.9 818 5

14070.8 1158.4 1090.9 36126.1 4419.4 8665.5 38190.1 7821.1 3338 23027.8 2378 1158.9 3

11098.5 2042.2 8417.1 214369.1 2448.1 3037.3 310960.7 1642.4 2

3059.3 22444.8 7150.8 664 3

11604.9 3991.8 25272.5 1210.2 28794.5 888.9 34303.9 2894.5 857.1 314648 6046.5 1055.3 2

1676.4 4243.8 1214.6 214882.4 6381.5 3

3500.8 216.7 36664.3 628 41520.3 212583 814.2 3754.2 5389.9 1036.7 2682.5 174.2 4677.6 4

54.8 4732.4 312339.2 822.2 1764.2 3

649.8 3630.8 669.5 414680.2 214821.9 3

469 1623 3244.8 3831.2 3

10213.6 171.1 310884 2869.4 2383.6 3235 5

0 0 0 06603.4 1017 3

14271.6 1290 37690.1 2

1457 892 51037.9 2

1055.5 8883.8 24192.7 5548.1 25921.5 516.5 4

13136.5 4100.9 22810 2081.7 3

9135.3 2832.2 2475.7 21917.7 7011.5 6820.4 2

15894.2 2506.7 5612.6 215471.4 3313.6 1151.4 2

7605.9 806.3 512937.8 5799.5 2137.9 2

6285.5 2127.5 24810.3 2483.7 2

14234.5 28573.5 436 3

10596.2 7709.2 311459.4 559.4 526.4 610837.8 12467 1178 2

655 538.6 42091.9 2477.4 8385.3 33136.8 2

2899.2 1213.5 1328.5 3

10987.7 658.5 414511.3 629.7 6472.4 4

7620.9 5972.6 27962 9092.9 2

1976.5 1900.7 26320.6 1058 7566.1 2

1617.9 314770.4 605.5 2

15501 3427.5 5524.3 215781.5 2052.7 374.2 4

11292.9 6760.6 29987.3 2409.8 3040.6 3

2608 1617.1 311534.3 498 3

9854.3 1557 22250.8 2

11539.1 6781.2 29189.1 5466.8 7351.3 2

4345.7 29366.7 8346.3 24694.9 12569.5 1672.2 25814.4 4630.3 5865.9 25657.4 4437 2

6374.8 21088.6 208.2 310671 4421.4 2393.8 2568.2 3

8892.9 4180.4 3569.4 214570.8 357.9 1110 3

5376 21793.3 9986.1 7206.9 3

11731.7 1463 2969.3 27072 1006.6 3

1490.7 2480.7 22986.9 7240.5 1592.5 39105.4 2854.2 2

12198.8 1361.3 214152.7 4113.9 3

4992.7 4067.8 21653.5 815 415526 522.8 4450.7 3

14064.6 22062.5 512.3 2903.1 4

14247.1 1880.9 24451.7 133 3

1572.4 651.8 33806.8 330.4 4

10417.2 3495.8 22961 646.3 4

5126.1 2108.2 604.4 44702.7 6782.2 23428.9 11983.5 2

379.2 442.9 2561.9 5582.7 4

9037.7 438.2 3646.6 38889.1 9344.2 3

13265.4 7464.8 27637.9 2

12069.3 9917.8 2561.8 214449.9 681.6 1986.6 3

503.2 4

346 1877.5 36981.6 1895.1 1359.7 23519.4 1258 739.7 3

13875.6 5168.8 34539.9 27272.9 2080.8 2

11971.6 1257.8 310651.1 602.8 854.4 4

514.8 720.6 43501.3 1524.3 24638.6 6817.6 2

660.5 10469.6 2340 410301.3 3643.4 4471 3

1293.2 2088.5 212686.1 738.6 4

4925.2 4960.9 26956.5 1308.4 25782.3 7062.1 1385.7 2

251.3 986.9 56065.3 566.8 3

15558.3 211972 3896.7 986.2 4

6195.8 37836 1933.7 2

594.5 5997.8 216.5 59410.1 327.4 33536.6 3568.7 4790 2

1259 3737.5 1986.2 393.1 3666.4 2842.9 3

311324.6 972.1 890.4 3

5723 3092.8 2278.2 410539.1 6387.9 2

822.9 39272.9 995.4 4637.1 2

12066.2 1107.8 310245.5 12260.9 2

9456.3 1076.9 2644.9 213006.6 547.6 4607 3

543.5 675.2 984.8 62

4261 11229.4 244 10596.2 3

3

8164.1 8930.6 35175.5 10034.3 5712.9 2

24967.1 469.6 2

14972.5 8363.2 2021.8 22

1560.6 1375.7 7271.7 3

Supplementary Table S4 : Wild type HTT coexpressed genes (http://www.GeneFriends.org)Gene Name Mutual RankHTT huntingtin 0TRAF3 TNF receptor-associated factor 3 1.4ZNF318 zinc finger protein 318 3.7ARHGAP17 Rho GTPase activating protein 17 1.7CMTR1 cap methyltransferase 1 2WDFY4 WDFY family member 4 23FNBP1 formin binding protein 1 25.3PIK3R6 phosphoinositide-3-kinase, regulatory subunit 6 27.1NEK6 NIMA-related kinase 6 16.2TRAF1 TNF receptor-associated factor 1 33.3HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin 12.8PPP1R16B protein phosphatase 1, regulatory subunit 16B 27.7INPP5B inositol polyphosphate-5-phosphatase, 75kDa 8.5TRRAP transformation/transcription domain-associated protei 18.7FMNL3 formin-like 3 20.5TNFRSF8 tumor necrosis factor receptor superfamily, member 8 44.2EHMT1 euchromatic histone-lysine N-methyltransferase 1 5.7PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specif 54.2TBC1D22A TBC1 domain family, member 22A 27.2PAX5 paired box 5 47.3SYMPK symplekin 38.7NFKB1 nuclear factor of kappa light polypeptide gene enhancer 47.8TNFRSF13C tumor necrosis factor receptor superfamily, member 1 52.6TSPAN33 tetraspanin 33 57.7SNX29 sorting nexin 29 13MCM3AP minichromosome maintenance complex component 3 as 31.6IRF5 interferon regulatory factor 5 71.9VAV2 vav 2 guanine nucleotide exchange factor 7.3EP400 E1A binding protein p400 35.5EDEM1 ER degradation enhancer, mannosidase alpha-like 1 49.4SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Ha 52.5ZBTB32 zinc finger and BTB domain containing 32 66.6WDR91 WD repeat domain 91 23.7POU2AF1 POU class 2 associating factor 1 74.6NUP210 nucleoporin 210kDa 36.9PRPF8 pre-mRNA processing factor 8 46.6CYFIP2 cytoplasmic FMR1 interacting protein 2 30.8SLAMF1 signaling lymphocytic activation molecule family memb 79.5UVRAG UV radiation resistance associated 38CNOT1 CCR4-NOT transcription complex, subunit 1 63.2RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 12.8IKZF2 IKAROS family zinc finger 2 (Helios) 67.8GPR55 G protein-coupled receptor 55 70.1TLR7 toll-like receptor 7 87.7ADPRH ADP-ribosylarginine hydrolase 88.7BCL2 B-cell CLL/lymphoma 2 60.2

PTK2B protein tyrosine kinase 2 beta 91.7ADAR adenosine deaminase, RNA-specific 42.7SIDT1 SID1 transmembrane family, member 1 61SKAP1 src kinase associated phosphoprotein 1 99SFMBT2 Scm-like with four mbt domains 2 25.7DOT1L DOT1-like histone H3K79 methyltransferase 44.3PARVB parvin, beta 78.1CLEC17A C-type lectin domain family 17, member A 103.2CD40 CD40 molecule, TNF receptor superfamily member 5 105.4TRAPPC10 trafficking protein particle complex 10 118.3LY75 lymphocyte antigen 75 109.9SREBF2 sterol regulatory element binding transcription factor 25.3LRRK1 leucine-rich repeat kinase 1 51.5FAM115C family with sequence similarity 115, member C 55.9MCOLN2 mucolipin 2 96.6CD226 CD226 molecule 93.5MAP4K1 mitogen-activated protein kinase kinase kinase kinase 120.6GCN1L1 GCN1 general control of amino-acid synthesis 1-like 1 ( 98MAP4K2 mitogen-activated protein kinase kinase kinase kinase 100RINL Ras and Rab interactor-like 116GPHN gephyrin 8.2AICDA activation-induced cytidine deaminase 101.2RFX5 regulatory factor X, 5 (influences HLA class II expressio 48.8UBR4 ubiquitin protein ligase E3 component n-recognin 4 55.1CD80 CD80 molecule 99.7FCHSD2 FCH and double SH3 domains 2 98.1ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 105.3OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 126.1SLAMF6 SLAM family member 6 146.5ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 12.5MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylgl 39

Sep-09 septin 9 72.9SNRNP200 small nuclear ribonucleoprotein 200kDa (U5) 105.9PRRC2A proline-rich coiled-coil 2A 112.1VOPP1 vesicular, overexpressed in cancer, prosurvival protein 92TNIP1 TNFAIP3 interacting protein 1 119.4RFTN1 raftlin, lipid raft linker 1 104.5RUNX3 runt-related transcription factor 3 138.3CARD11 caspase recruitment domain family, member 11 143.7LRCH1 leucine-rich repeats and calponin homology (CH) domai 63.6POM121 POM121 transmembrane nucleoporin 66.6ZC3H7A zinc finger CCCH-type containing 7A 46.2USP48 ubiquitin specific peptidase 48 54.5DUSP2 dual specificity phosphatase 2 125.8TP73 tumor protein p73 58.7ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial 87.4CD70 CD70 molecule 136.8ZC3H12D zinc finger CCCH-type containing 12D 144.5

IL21R interleukin 21 receptor 122.6MTA2 metastasis associated 1 family, member 2 111.1SNX25 sorting nexin 25 106.2UBR5 ubiquitin protein ligase E3 component n-recognin 5 103.4XPC xeroderma pigmentosum, complementation group C 46FBXO46 F-box protein 46 71.4NFKB2 nuclear factor of kappa light polypeptide gene enhancer 126.8SF3B3 splicing factor 3b, subunit 3, 130kDa 128.5IRF4 interferon regulatory factor 4 139.3TLR10 toll-like receptor 10 156.1SLX4 SLX4 structure-specific endonuclease subunit 66RNF31 ring finger protein 31 127.3CD48 CD48 molecule 183WNT10A wingless-type MMTV integration site family, member 131.8BTAF1 BTAF1 RNA polymerase II, B-TFIID transcription factor- 119.4

Sep-06 septin 6 159.5ZFAT zinc finger and AT hook domain containing 99.9KDM4B lysine (K)-specific demethylase 4B 108.5INTS3 integrator complex subunit 3 137TNFRSF13B tumor necrosis factor receptor superfamily, member 1 147.9CYTH1 cytohesin 1 274.1AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3 24.7SLC9A7 solute carrier family 9, subfamily A (NHE7, cation prot 35.1UBXN7 UBX domain protein 7 135.5MALT1 mucosa associated lymphoid tissue lymphoma transloc 135.1TNF tumor necrosis factor 163.8EPS15 epidermal growth factor receptor pathway substrate 1 115.5DHX37 DEAH (Asp-Glu-Ala-His) box polypeptide 37 168.6MYO1G myosin IG 188.7ANGPTL6 angiopoietin-like 6 168.3GBF1 golgi brefeldin A resistant guanine nucleotide exchange 75.3BATF basic leucine zipper transcription factor, ATF-like 175.5CLEC16A C-type lectin domain family 16, member A 278.2ZMAT3 zinc finger, matrin-type 3 45FOCAD focadhesin 93.3LTA lymphotoxin alpha 158.7TRIM26 tripartite motif containing 26 55.1SGPP2 sphingosine-1-phosphate phosphatase 2 58.2MED12 mediator complex subunit 12 117.1FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23) 157.5MS4A1 membrane-spanning 4-domains, subfamily A, member 181.5EDC4 enhancer of mRNA decapping 4 189.8ZFYVE26 zinc finger, FYVE domain containing 26 84.9RBM19 RNA binding motif protein 19 81.7HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 175.9PRRC2B proline-rich coiled-coil 2B 128.3MSC musculin 161.9CSK c-src tyrosine kinase 234

BTN2A2 butyrophilin, subfamily 2, member A2 81.8Putative eukaryotic translation initiation factor 2 subuni 100.5

IL2RB interleukin 2 receptor, beta 179.8MMS19 MMS19 nucleotide excision repair homolog (S. cerevisi 131.2ADRBK2 adrenergic, beta, receptor kinase 2 137.4IL4I1 interleukin 4 induced 1 149.3SLC15A4 solute carrier family 15 (oligopeptide transporter), me 175.2B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, p 40ZBED4 zinc finger, BED-type containing 4 103.9SLAMF7 SLAM family member 7 177.9CABLES1 Cdk5 and Abl enzyme substrate 1 60.1AARS2 alanyl-tRNA synthetase 2, mitochondrial 123.1THOP1 thimet oligopeptidase 1 209.5R3HDM1 R3H domain containing 1 104.8SEC16A SEC16 homolog A (S. cerevisiae) 118.8ANAPC1 anaphase promoting complex subunit 1 130.9TFEB transcription factor EB 225.4NCKAP1L NCK-associated protein 1-like 286.6RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regul 171STAT1 signal transducer and activator of transcription 1, 91kD 192.3DOCK2 dedicator of cytokinesis 2 459.5CD22 CD22 molecule 194.2TMED8 transmembrane emp24 protein transport domain conta 100.5AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 118.3HLA-DOA major histocompatibility complex, class II, DO alpha 189MIOS missing oocyte, meiosis regulator, homolog (Drosophila 84.4SEC24C SEC24 family member C 88.7RNGTT RNA guanylyltransferase and 5'-phosphatase 132.5CABIN1 calcineurin binding protein 1 172.3LCP1 lymphocyte cytosolic protein 1 (L-plastin) 294.5MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase 522LRCH3 leucine-rich repeats and calponin homology (CH) domai 162.1GRAP GRB2-related adaptor protein 242.1SIPA1L1 signal-induced proliferation-associated 1 like 1 150.4PHRF1 PHD and ring finger domains 1 184.5SIPA1L3 signal-induced proliferation-associated 1 like 3 36.6NOP14 NOP14 nucleolar protein 119.8VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae) 181.3HVCN1 hydrogen voltage-gated channel 1 280.9KCNN3 potassium intermediate/small conductance calcium-ac 152.2ABI3 ABI family, member 3 274MBD1 methyl-CpG binding domain protein 1 101.5MACROD2 MACRO domain containing 2 126.8ZNF292 zinc finger protein 292 449.7LILRB1 leukocyte immunoglobulin-like receptor, subfamily B 288.4KSR1 kinase suppressor of ras 1 20MAP3K4 mitogen-activated protein kinase kinase kinase 4 140.7SUGP2 SURP and G patch domain containing 2 153.5

CHD8 chromodomain helicase DNA binding protein 8 249.4ANKRD33B ankyrin repeat domain 33B 70.1C6orf223 chromosome 6 open reading frame 223 124.9DPP3 dipeptidyl-peptidase 3 170.8INVS inversin 250.7GLYR1 glyoxylate reductase 1 homolog (Arabidopsis) 133.8PGAM4 phosphoglycerate mutase family member 4 172.9ANXA6 annexin A6 184.4SCIMP SLP adaptor and CSK interacting membrane protein 217.9ACTR2 ARP2 actin-related protein 2 homolog (yeast) 232.5MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) 114.3SNX11 sorting nexin 11 232.8ZNF317 zinc finger protein 317 113.2TBC1D5 TBC1 domain family, member 5 210.9JADE2 jade family PHD finger 2 95.9BLK B lymphoid tyrosine kinase 233.6TYK2 tyrosine kinase 2 324.3KIAA1432 KIAA1432 204.2TRAP1 TNF receptor-associated protein 1 249.8PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisia 62CEP250 centrosomal protein 250kDa 141.2GCSAM germinal center-associated, signaling and motility 230.5INCENP inner centromere protein antigens 135/155kDa 258.1ELK1 ELK1, member of ETS oncogene family 123.2LMNB1 lamin B1 217.5CLECL1 C-type lectin-like 1 233BCAS4 breast carcinoma amplified sequence 4 261.5WDR33 WD repeat domain 33 256.5ZZEF1 zinc finger, ZZ-type with EF-hand domain 1 578.9UBE2J1 ubiquitin-conjugating enzyme E2, J1 238.5PI4KA phosphatidylinositol 4-kinase, catalytic, alpha 394.8

Supplementary Table S4 : Wild type HTT coexpressed genes (http://www.GeneFriends.org)Pearson Correlatio Chromosome

1 40.71 14

0.696 60.655 160.654 60.637 100.637 90.619 170.614 90.612 90.606 X0.606 200.602 10.595 70.595 120.594 1

0.59 90.586 160.585 220.585 90.584 190.584 40.581 220.581 70.568 160.566 210.564 70.563 90.561 120.558 30.557 150.556 190.555 70.555 110.552 30.552 17

0.55 50.55 1

0.549 110.549 160.548 90.546 20.546 20.542 X0.542 30.541 18

0.541 80.54 10.54 3

0.538 170.537 100.537 190.537 220.537 190.537 200.537 210.536 20.534 220.531 150.531 70.529 10.528 180.527 190.526 120.526 110.525 190.522 140.522 120.521 10.521 10.521 3

0.52 110.52 100.52 120.52 1

0.516 130.516 220.516 170.515 20.514 60.512 70.512 5

0.51 30.509 10.508 70.507 130.507 70.506 160.506 10.506 20.505 10.505 180.505 190.505 6

0.503 160.502 110.501 4

0.5 80.499 30.499 190.499 100.499 160.499 60.499 40.498 160.498 140.498 10.497 20.495 100.495 X0.494 80.494 190.494 10.494 170.493 170.491 210.491 X0.491 3

0.49 180.49 6

0.489 10.488 120.488 70.487 190.486 100.486 140.486 160.485 30.485 90.485 60.484 60.484 20.484 X0.484 190.484 110.483 160.482 140.481 120.481 6

0.48 90.48 80.48 15

0.479 60.479 120.479 220.478 100.478 220.478 190.478 120.476 180.476 220.476 10.475 180.475 60.475 190.474 20.474 90.474 20.474 60.474 120.472 20.472 20.472 5

0.47 190.469 140.469 80.469 60.468 70.468 100.467 60.467 220.467 130.467 130.466 30.466 170.465 140.465 110.463 190.463 40.463 150.463 120.462 10.462 170.461 180.461 200.461 6

0.46 190.458 170.458 60.458 19

0.457 140.455 50.455 60.455 110.455 90.454 160.454 X0.454 50.454 170.454 20.453 70.453 170.452 190.452 30.451 50.451 80.451 19

0.45 90.45 16

0.449 70.449 200.449 30.449 110.448 X0.448 50.448 120.448 200.447 20.446 170.445 60.445 22

Supplementary Table S5A Decreased expression of genes in the caudate of HD with p≤0.001 (Hodges et al. 2006)Associated Gene Name Description Chromosome NameAASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopante 11ABAT 4-aminobutyrate aminotransferase 16ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9 12ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 3ABI2 abl-interactor 2 2ABLIM2 actin binding LIM protein family, member 2 4ABTB1 ankyrin repeat and BTB (POZ) domain containing 1 3ACE angiotensin I converting enzyme 17ACHE acetylcholinesterase (Yt blood group) 7ACLY ATP citrate lyase 17ACP1 acid phosphatase 1, soluble 2ACSL6 acyl-CoA synthetase long-chain family member 6 5ACTB actin, beta 7ACTN1 actinin, alpha 1 14ACTN2 actinin, alpha 2 1ACTR10 actin-related protein 10 homolog (S. cerevisiae) 14ACTR1A ARP1 actin-related protein 1 homolog A, centractin alpha 10ACTR1B ARP1 actin-related protein 1 homolog B, centractin beta ( 2ACTR3 ARP3 actin-related protein 3 homolog (yeast) 2ACVR1B activin A receptor, type IB 12ACYP2 acylphosphatase 2, muscle type 2ADAM12 ADAM metallopeptidase domain 12 10ADAM23 ADAM metallopeptidase domain 23 2ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 moti 4ADAMTS8 ADAM metallopeptidase with thrombospondin type 1 moti 11ADARB1 adenosine deaminase, RNA-specific, B1 21ADCY1 adenylate cyclase 1 (brain) 7ADCY3 adenylate cyclase 3 2ADCY5 adenylate cyclase 5 3ADCY9 adenylate cyclase 9 16ADD2 adducin 2 (beta) 2ADK adenosine kinase 10ADORA2A adenosine A2a receptor 22ADRA2C adrenoceptor alpha 2C 4ADRB1 adrenoceptor beta 1 10ADRBK1 adrenergic, beta, receptor kinase 1 11AES amino-terminal enhancer of split 19AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1 6AK5 adenylate kinase 5 1AKAP11 A kinase (PRKA) anchor protein 11 13AKAP12 A kinase (PRKA) anchor protein 12 6AKAP5 A kinase (PRKA) anchor protein 5 14AKAP6 A kinase (PRKA) anchor protein 6 14ALAS1 5'-aminolevulinate synthase 1 3ALDH3A2 aldehyde dehydrogenase 3 family, member A2 17ALDOA aldolase A, fructose-bisphosphate 16

ALK anaplastic lymphoma receptor tyrosine kinase 2AMBN ameloblastin (enamel matrix protein) 4AMMECR1 Alport syndrome, mental retardation, midface hypoplasiaXAMPD2 adenosine monophosphate deaminase 2 1AMPH amphiphysin 7ANAPC1 anaphase promoting complex subunit 1 2ANAPC7 anaphase promoting complex subunit 7 12ANK2 ankyrin 2, neuronal 4ANK3 ankyrin 3, node of Ranvier (ankyrin G) 10ANKH ANKH inorganic pyrophosphate transport regulator 5ANXA6 annexin A6 5AP1G1 adaptor-related protein complex 1, gamma 1 subunit 16AP1S1 adaptor-related protein complex 1, sigma 1 subunit 7AP2A1 adaptor-related protein complex 2, alpha 1 subunit 19AP2A2 adaptor-related protein complex 2, alpha 2 subunit 11AP2B1 adaptor-related protein complex 2, beta 1 subunit 17AP2M1 adaptor-related protein complex 2, mu 1 subunit 3AP3B2 adaptor-related protein complex 3, beta 2 subunit 15AP3D1 adaptor-related protein complex 3, delta 1 subunit 19AP3M2 adaptor-related protein complex 3, mu 2 subunit 8AP3S1 adaptor-related protein complex 3, sigma 1 subunit 5AP4B1 adaptor-related protein complex 4, beta 1 subunit 1AP4S1 adaptor-related protein complex 4, sigma 1 subunit 14APBA1 amyloid beta (A4) precursor protein-binding, family A, m 9API5 apoptosis inhibitor 5 11APLP2 amyloid beta (A4) precursor-like protein 2 11APP amyloid beta (A4) precursor protein 21ARC activity-regulated cytoskeleton-associated protein 8ARF1 ADP-ribosylation factor 1 1ARF3 ADP-ribosylation factor 3 12ARF4 ADP-ribosylation factor 4 3ARF5 ADP-ribosylation factor 5 7ARG2 arginase 2 14ARHGAP20 Rho GTPase activating protein 20 11ARHGAP26 Rho GTPase activating protein 26 5ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 17ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma 16ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 1ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4 2ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 13ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9 XARL2 ADP-ribosylation factor-like 2 11ARL6 ADP-ribosylation factor-like 6 3ARNTL aryl hydrocarbon receptor nuclear translocator-like 11ARPC1A actin related protein 2/3 complex, subunit 1A, 41kDa 7ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa 2ARPC5L actin related protein 2/3 complex, subunit 5-like 9ARV1 ARV1 homolog (S. cerevisiae) 1

ASAH2 N-acylsphingosine amidohydrolase (non-lysosomal cerami 10ASB17 ankyrin repeat and SOCS box containing 17 1ASB6 ankyrin repeat and SOCS box containing 6 9ASNA1 arsA arsenite transporter, ATP-binding, homolog 1 (bacter 19ASNS asparagine synthetase (glutamine-hydrolyzing) 7ATAD1 ATPase family, AAA domain containing 1 10ATCAY ataxia, cerebellar, Cayman type 19ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 1ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide 19ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 12ATP2A3 ATPase, Ca++ transporting, ubiquitous 17ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 12ATP2B2 ATPase, Ca++ transporting, plasma membrane 2 3ATP2B3 ATPase, Ca++ transporting, plasma membrane 3 XATP2C1 ATPase, Ca++ transporting, type 2C, member 1 3ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, 18ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex 12ATP5C1 ATP synthase, H+ transporting, mitochondrial F1 comple 10ATP5G1 ATP synthase, H+ transporting, mitochondrial Fo complex, 17ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex, 2ATP5H ATP synthase, H+ transporting, mitochondrial Fo complex, 17ATP5L ATP synthase, H+ transporting, mitochondrial Fo complex, 11ATP5O ATP synthase, H+ transporting, mitochondrial F1 complex, 21ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1 17ATP6V0C ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c 16ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit 8ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 8ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 14ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 22ATP6V1F ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F 7ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 6ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit 8ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, t 4ATP8A2 ATPase, aminophospholipid transporter, class I, type 8A, 13ATP9A ATPase, class II, type 9A 20ATPAF1 ATP synthase mitochondrial F1 complex assembly factor 1 1ATPIF1 ATPase inhibitory factor 1 1ATRN attractin 20ATRX alpha thalassemia/mental retardation syndrome X-linkedXAUH AU RNA binding protein/enoyl-CoA hydratase 9B3GALT2 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, poly 1B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransf 12B3GNT6 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransf 11B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, poly 18BAG4 BCL2-associated athanogene 4 8BAIAP2 BAI1-associated protein 2 17BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal h 3BASP1 brain abundant, membrane attached signal protein 1 5

BATF basic leucine zipper transcription factor, ATF-like 14BBS7 Bardet-Biedl syndrome 7 4BCAS2 breast carcinoma amplified sequence 2 1BCAS4 breast carcinoma amplified sequence 4 20BCAT1 branched chain amino-acid transaminase 1, cytosolic 12BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) 2BCL11B B-cell CLL/lymphoma 11B (zinc finger protein) 14BCL2L10 BCL2-like 10 (apoptosis facilitator) 15BCL7B B-cell CLL/lymphoma 7B 7BCLAF1 BCL2-associated transcription factor 1 6BCR breakpoint cluster region 22BDP1 B double prime 1, subunit of RNA polymerase III transcripti 5BEX1 brain expressed, X-linked 1 XBEX2 brain expressed X-linked 2 XBID BH3 interacting domain death agonist 22BLCAP bladder cancer associated protein 20BMPER BMP binding endothelial regulator 7BMPR2 bone morphogenetic protein receptor, type II (serine/thr 2BOP1 block of proliferation 1 8BPNT1 3'(2'), 5'-bisphosphate nucleotidase 1 1BRE brain and reproductive organ-expressed (TNFRSF1A modu 2BRIP1 BRCA1 interacting protein C-terminal helicase 1 17BRMS1L breast cancer metastasis-suppressor 1-like 14BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin) 11BSN bassoon presynaptic cytomatrix protein 3BSPRY B-box and SPRY domain containing 9BTBD11 BTB (POZ) domain containing 11 12BTBD2 BTB (POZ) domain containing 2 19BTBD6 BTB (POZ) domain containing 6 14BTBD9 BTB (POZ) domain containing 9 6BTRC beta-transducin repeat containing E3 ubiquitin protein lig 10BUB1B BUB1 mitotic checkpoint serine/threonine kinase B 15BZRAP1 benzodiazepine receptor (peripheral) associated protein 17BZW2 basic leucine zipper and W2 domains 2 7C11orf1 chromosome 11 open reading frame 1 11C14orf2 chromosome 14 open reading frame 2 14C19orf12 chromosome 19 open reading frame 12 19C1QTNF4 C1q and tumor necrosis factor related protein 4 11C20orf24 chromosome 20 open reading frame 24 20C20orf27 chromosome 20 open reading frame 27 20C6orf136 chromosome 6 open reading frame 136 6C9orf152 chromosome 9 open reading frame 152 9C9orf16 chromosome 9 open reading frame 16 9C9orf41 chromosome 9 open reading frame 41 9CA11 carbonic anhydrase XI 19CA12 carbonic anhydrase XII 15CA7 carbonic anhydrase VII 16CABP1 calcium binding protein 1 12

CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A 19CACNA1B calcium channel, voltage-dependent, N type, alpha 1B sub 9CACNA1E calcium channel, voltage-dependent, R type, alpha 1E sub 1CACNA1H calcium channel, voltage-dependent, T type, alpha 1H sub 16CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subu 22CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subuni 7CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subuni 3CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta subuni 3CACNB1 calcium channel, voltage-dependent, beta 1 subunit 17CACNB2 calcium channel, voltage-dependent, beta 2 subunit 10CACNB3 calcium channel, voltage-dependent, beta 3 subunit 12CACNB4 calcium channel, voltage-dependent, beta 4 subunit 2CACNG2 calcium channel, voltage-dependent, gamma subunit 2 22CACNG3 calcium channel, voltage-dependent, gamma subunit 3 16CACNG4 calcium channel, voltage-dependent, gamma subunit 4 17CADPS Ca++-dependent secretion activator 3CALB1 calbindin 1, 28kDa 8CALM1 calmodulin 1 (phosphorylase kinase, delta) 14CALM3 calmodulin 3 (phosphorylase kinase, delta) 19CALN1 calneuron 1 7CALU calumenin 7CAMK1 calcium/calmodulin-dependent protein kinase I 3CAMK1D calcium/calmodulin-dependent protein kinase ID 10CAMK1G calcium/calmodulin-dependent protein kinase IG 1CAMK2A calcium/calmodulin-dependent protein kinase II alpha 5CAMK2B calcium/calmodulin-dependent protein kinase II beta 7CAMK4 calcium/calmodulin-dependent protein kinase IV 5CAMKK1 calcium/calmodulin-dependent protein kinase kinase 1, a 17CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, b 12CAMTA2 calmodulin binding transcription activator 2 17CAP2 CAP, adenylate cyclase-associated protein, 2 (yeast) 6CARHSP1 calcium regulated heat stable protein 1, 24kDa 16CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translo 16CBX6 chromobox homolog 6 22CCDC3 coiled-coil domain containing 3 10CCDC6 coiled-coil domain containing 6 10CCKBR cholecystokinin B receptor 11CCM2 cerebral cavernous malformation 2 7CCNB1 cyclin B1 5CCNDBP1 cyclin D-type binding-protein 1 15CCNG2 cyclin G2 4CCT2 chaperonin containing TCP1, subunit 2 (beta) 12CD47 CD47 molecule 3CD8A CD8a molecule 2CDC23 cell division cycle 23 5CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 16CDH12 cadherin 12, type 2 (N-cadherin 2) 5CDH18 cadherin 18, type 2 5

CDH6 cadherin 6, type 2, K-cadherin (fetal kidney) 5CDH7 cadherin 7, type 2 18CDH8 cadherin 8, type 2 16CDH9 cadherin 9, type 2 (T1-cadherin) 5CDK5 cyclin-dependent kinase 5 7CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) 17CDK5R2 cyclin-dependent kinase 5, regulatory subunit 2 (p39) 2CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) 19CDO1 cysteine dioxygenase type 1 5CDR1 cerebellar degeneration-related protein 1, 34kDa XCDR2 cerebellar degeneration-related protein 2, 62kDa 16CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltrans 4CECR6 cat eye syndrome chromosome region, candidate 6 22CFC1 cripto, FRL-1, cryptic family 1 2CHAD chondroadherin 17CHCHD4 coiled-coil-helix-coiled-coil-helix domain containing 4 3CHCHD6 coiled-coil-helix-coiled-coil-helix domain containing 6 3CHD3 chromodomain helicase DNA binding protein 3 17CHGB chromogranin B 20CHL1 cell adhesion molecule L1-like 3CHN1 chimerin 1 2CHN2 chimerin 2 7CHRM1 cholinergic receptor, muscarinic 1 11CHRM4 cholinergic receptor, muscarinic 4 11CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal) 1CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 11CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 3CIAO1 cytosolic iron-sulfur assembly component 1 2CIDEA cell death-inducing DFFA-like effector a 18CIRH1A cirrhosis, autosomal recessive 1A (cirhin) 16CIT citron rho-interacting serine/threonine kinase 12CLASP2 cytoplasmic linker associated protein 2 3CLCN4 chloride channel, voltage-sensitive 4 XCLDN12 claudin 12 7CLPTM1 cleft lip and palate associated transmembrane protein 1 19CLSTN3 calsyntenin 3 12CLTB clathrin, light chain B 5CLTC clathrin, heavy chain (Hc) 17CNNM1 cyclin and CBS domain divalent metal cation transport me 10CNOT4 CCR4-NOT transcription complex, subunit 4 7CNR1 cannabinoid receptor 1 (brain) 6CNTN1 contactin 1 12CNTN4 contactin 4 3CNTNAP1 contactin associated protein 1 17CNTNAP3 contactin associated protein-like 3 9COCH cochlin 14COG1 component of oligomeric golgi complex 1 17COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding 5

COPS3 COP9 signalosome subunit 3 17COPS6 COP9 signalosome subunit 6 7COPS8 COP9 signalosome subunit 8 2COQ3 coenzyme Q3 methyltransferase 6COQ4 coenzyme Q4 9COQ6 coenzyme Q6 monooxygenase 14CORO2A coronin, actin binding protein, 2A 9CORO2B coronin, actin binding protein, 2B 15CORT cortistatin 1COX11 COX11 cytochrome c oxidase copper chaperone 17COX4I1 cytochrome c oxidase subunit IV isoform 1 16COX5B cytochrome c oxidase subunit Vb 2COX6A1 cytochrome c oxidase subunit VIa polypeptide 1 12COX6C cytochrome c oxidase subunit VIc 8COX7A2 cytochrome c oxidase subunit VIIa polypeptide 2 (liver) 6COX7A2L cytochrome c oxidase subunit VIIa polypeptide 2 like 2COX7C cytochrome c oxidase subunit VIIc 5CPLX1 complexin 1 4CPLX2 complexin 2 5CPNE4 copine IV 3CPNE5 copine V 6CPT1C carnitine palmitoyltransferase 1C 19CREBL2 cAMP responsive element binding protein-like 2 12CRELD1 cysteine-rich with EGF-like domains 1 3CREM cAMP responsive element modulator 10CRH corticotropin releasing hormone 8CRMP1 collapsin response mediator protein 1 4CRNKL1 crooked neck pre-mRNA splicing factor 1 20CRYM crystallin, mu 16CSMD1 CUB and Sushi multiple domains 1 8CSNK1G3 casein kinase 1, gamma 3 5CSPG5 chondroitin sulfate proteoglycan 5 (neuroglycan C) 3CSRP2BP CSRP2 binding protein 20CTXN1 cortexin 1 19CUL2 cullin 2 10CUL3 cullin 3 2CX3CL1 chemokine (C-X3-C motif) ligand 1 16CXCL14 chemokine (C-X-C motif) ligand 14 5CYB561 cytochrome b561 17CYCS cytochrome c, somatic 7CYFIP2 cytoplasmic FMR1 interacting protein 2 5CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 10CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1 14CYP4X1 cytochrome P450, family 4, subfamily X, polypeptide 1 1CYP4Z1 cytochrome P450, family 4, subfamily Z, polypeptide 1 1DAB2IP DAB2 interacting protein 9DACH1 dachshund family transcription factor 1 13DACH2 dachshund family transcription factor 2 X

DAPK1 death-associated protein kinase 1 9DBN1 drebrin 1 5DCC DCC netrin 1 receptor 18DCK deoxycytidine kinase 4DCTN1 dynactin 1 2DCTN3 dynactin 3 (p22) 9DCX doublecortin XDDC dopa decarboxylase (aromatic L-amino acid decarboxylase 7DDO D-aspartate oxidase 6DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 11DDX24 DEAD (Asp-Glu-Ala-Asp) box helicase 24 14DDX25 DEAD (Asp-Glu-Ala-Asp) box helicase 25 11DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 17DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 12DEAF1 DEAF1 transcription factor 11DGAT2 diacylglycerol O-acyltransferase 2 11DGKA diacylglycerol kinase, alpha 80kDa 12DGKB diacylglycerol kinase, beta 90kDa 7DGKI diacylglycerol kinase, iota 7DGKZ diacylglycerol kinase, zeta 11DGUOK deoxyguanosine kinase 2DHPS deoxyhypusine synthase 19DHX36 DEAH (Asp-Glu-Ala-His) box polypeptide 36 3DIAPH1 diaphanous-related formin 1 5DIAPH2 diaphanous-related formin 2 XDIO2 deiodinase, iodothyronine, type II 14DIRAS1 DIRAS family, GTP-binding RAS-like 1 19DIRAS2 DIRAS family, GTP-binding RAS-like 2 9DKK3 dickkopf WNT signaling pathway inhibitor 3 11DLAT dihydrolipoamide S-acetyltransferase 11DLC1 DLC1 Rho GTPase activating protein 8DLD dihydrolipoamide dehydrogenase 7DLG2 discs, large homolog 2 (Drosophila) 11DLG3 discs, large homolog 3 (Drosophila) XDLG4 discs, large homolog 4 (Drosophila) 17DLGAP1 discs, large (Drosophila) homolog-associated protein 1 18DLGAP2 discs, large (Drosophila) homolog-associated protein 2 8DLGAP3 discs, large (Drosophila) homolog-associated protein 3 1DLL3 delta-like 3 (Drosophila) 19DLL4 delta-like 4 (Drosophila) 15DLX5 distal-less homeobox 5 7DLX6 distal-less homeobox 6 7DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2 16DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4 15DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5 9DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 10DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 20DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7 17

DNAL4 dynein, axonemal, light chain 4 22DNM1 dynamin 1 9DNM1L dynamin 1-like 12DOCK11 dedicator of cytokinesis 11 XDOCK3 dedicator of cytokinesis 3 3DPCD deleted in primary ciliary dyskinesia homolog (mouse) 10DPF1 D4, zinc and double PHD fingers family 1 19DPM1 dolichyl-phosphate mannosyltransferase polypeptide 1, ca 20DPP6 dipeptidyl-peptidase 6 7DPYSL4 dihydropyrimidinase-like 4 10DPYSL5 dihydropyrimidinase-like 5 2DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 11DRD1 dopamine receptor D1 5DRD2 dopamine receptor D2 11DRD3 dopamine receptor D3 3DSCAML1 Down syndrome cell adhesion molecule like 1 11DTNBP1 dystrobrevin binding protein 1 6DUSP14 dual specificity phosphatase 14 17DUSP2 dual specificity phosphatase 2 2DUSP6 dual specificity phosphatase 6 12DUSP8 dual specificity phosphatase 8 11EAF1 ELL associated factor 1 3EBF2 early B-cell factor 2 8EBNA1BP2 EBNA1 binding protein 2 1EBP emopamil binding protein (sterol isomerase) XECE2 endothelin converting enzyme 2 3EEF1A2 eukaryotic translation elongation factor 1 alpha 2 20EFNA3 ephrin-A3 1EFNB2 ephrin-B2 13EFNB3 ephrin-B3 17EGLN2 egl-9 family hypoxia-inducible factor 2 19EGR1 early growth response 1 5EGR3 early growth response 3 8EGR4 early growth response 4 2EHD3 EH-domain containing 3 2EIF2A eukaryotic translation initiation factor 2A, 65kDa 3EIF4A2 eukaryotic translation initiation factor 4A2 3EIF5A2 eukaryotic translation initiation factor 5A2 3ELF3 E74-like factor 3 (ets domain transcription factor, epithelia 1ELK1 ELK1, member of ETS oncogene family XELMO1 engulfment and cell motility 1 7ELMO2 engulfment and cell motility 2 20ELOVL2 ELOVL fatty acid elongase 2 6ELOVL4 ELOVL fatty acid elongase 4 6EML1 echinoderm microtubule associated protein like 1 14ENC1 ectodermal-neural cortex 1 (with BTB domain) 5ENO2 enolase 2 (gamma, neuronal) 12ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3 3

ENTPD6 ectonucleoside triphosphate diphosphohydrolase 6 (putat 20EPB41 erythrocyte membrane protein band 4.1 1EPB41L1 erythrocyte membrane protein band 4.1-like 1 20EPB41L2 erythrocyte membrane protein band 4.1-like 2 6EPB41L4B erythrocyte membrane protein band 4.1 like 4B 9EPHA4 EPH receptor A4 2EPHA7 EPH receptor A7 6EPHB1 EPH receptor B1 3EPHB6 EPH receptor B6 7ERO1L ERO1-like (S. cerevisiae) 14ESRRG estrogen-related receptor gamma 1ETV1 ets variant 1 7ETV5 ets variant 5 3EVL Enah/Vasp-like 14EXOSC6 exosome component 6 16EXTL2 exostosin-like glycosyltransferase 2 1EXTL3 exostosin-like glycosyltransferase 3 8EYA1 EYA transcriptional coactivator and phosphatase 1 8F12 coagulation factor XII (Hageman factor) 5F8 coagulation factor VIII, procoagulant component XFABP3 fatty acid binding protein 3, muscle and heart 1FABP6 fatty acid binding protein 6, ileal 5FAIM2 Fas apoptotic inhibitory molecule 2 12FAM3C family with sequence similarity 3, member C 7FAT3 FAT atypical cadherin 3 11FBLN5 fibulin 5 14FBXL2 F-box and leucine-rich repeat protein 2 3FBXO16 F-box protein 16 8FBXO3 F-box protein 3 11FBXO33 F-box protein 33 14FBXO34 F-box protein 34 14FBXO9 F-box protein 9 6FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin pr 4FEZ1 fasciculation and elongation protein zeta 1 (zygin I) 11FGF12 fibroblast growth factor 12 3FGF13 fibroblast growth factor 13 XFGF14 fibroblast growth factor 14 13FGF9 fibroblast growth factor 9 13FH fumarate hydratase 1FHOD3 formin homology 2 domain containing 3 18FKBP11 FK506 binding protein 11, 19 kDa 12FKBP1A FK506 binding protein 1A, 12kDa 20FKBP1B FK506 binding protein 1B, 12.6 kDa 2FKBP3 FK506 binding protein 3, 25kDa 14FKBP4 FK506 binding protein 4, 59kDa 12FKBP8 FK506 binding protein 8, 38kDa 19FKRP fukutin related protein 19FNDC5 fibronectin type III domain containing 5 1

FOSB FBJ murine osteosarcoma viral oncogene homolog B 19FOXP1 forkhead box P1 3FRAS1 Fraser extracellular matrix complex subunit 1 4FSD1 fibronectin type III and SPRY domain containing 1 19FTCD formimidoyltransferase cyclodeaminase 21FTSJ1 FtsJ RNA methyltransferase homolog 1 (E. coli) XFUNDC1 FUN14 domain containing 1 XFUT11 fucosyltransferase 11 (alpha (1,3) fucosyltransferase) 10FXYD7 FXYD domain containing ion transport regulator 7 19FZD2 frizzled class receptor 2 17G3BP2 GTPase activating protein (SH3 domain) binding protein 2 4GABARAPL1 GABA(A) receptor-associated protein like 1 12GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1 6GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 5GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4 4GABRA5 gamma-aminobutyric acid (GABA) A receptor, alpha 5 15GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 15GABRD gamma-aminobutyric acid (GABA) A receptor, delta 1GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2 5GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3 15GAD1 glutamate decarboxylase 1 (brain, 67kDa) 2GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 6 10GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 18GALNT13 polypeptide N-acetylgalactosaminyltransferase 13 2GALNT15 polypeptide N-acetylgalactosaminyltransferase 15 3GAP43 growth associated protein 43 3GARS glycyl-tRNA synthetase 7GAS7 growth arrest-specific 7 17GBF1 golgi brefeldin A resistant guanine nucleotide exchange fa 10GCH1 GTP cyclohydrolase 1 14GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2 9GDAP1 ganglioside induced differentiation associated protein 1 8GDAP1L1 ganglioside induced differentiation associated protein 1-li 20GDF11 growth differentiation factor 11 12GFRA1 GDNF family receptor alpha 1 10GGA2 golgi-associated, gamma adaptin ear containing, ARF bind 16GGA3 golgi-associated, gamma adaptin ear containing, ARF bind 17GGH gamma-glutamyl hydrolase (conjugase, folylpolygammagl 8GHITM growth hormone inducible transmembrane protein 10GIT1 G protein-coupled receptor kinase interacting ArfGAP 1 17GIT2 G protein-coupled receptor kinase interacting ArfGAP 2 12GJC1 gap junction protein, gamma 1, 45kDa 17GLCCI1 glucocorticoid induced 1 7GLCE glucuronic acid epimerase 15GLRB glycine receptor, beta 4GLRX2 glutaredoxin 2 1GLS glutaminase 2GMDS GDP-mannose 4,6-dehydratase 6

GNAL guanine nucleotide binding protein (G protein), alpha acti 18GNAQ guanine nucleotide binding protein (G protein), q polypep 9GNB1 guanine nucleotide binding protein (G protein), beta poly 1GNB5 guanine nucleotide binding protein (G protein), beta 5 15GNG3 guanine nucleotide binding protein (G protein), gamma 3 11GNG4 guanine nucleotide binding protein (G protein), gamma 4 1GNG7 guanine nucleotide binding protein (G protein), gamma 7 19GOT1 glutamic-oxaloacetic transaminase 1, soluble 10GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 16GP1BB glycoprotein Ib (platelet), beta polypeptide 22GPC1 glypican 1 2GPC5 glypican 5 13GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial) 2GPHN gephyrin 14GPI glucose-6-phosphate isomerase 19GPM6A glycoprotein M6A 4GPR12 G protein-coupled receptor 12 13GPR155 G protein-coupled receptor 155 2GPR158 G protein-coupled receptor 158 10GPR22 G protein-coupled receptor 22 7GPR27 G protein-coupled receptor 27 3GPR52 G protein-coupled receptor 52 1GPR6 G protein-coupled receptor 6 6GPR63 G protein-coupled receptor 63 6GPR85 G protein-coupled receptor 85 7GPR88 G protein-coupled receptor 88 1GPX4 glutathione peroxidase 4 19GRASP GRP1 (general receptor for phosphoinositides 1)-associate 12GRB10 growth factor receptor-bound protein 10 7GRB2 growth factor receptor-bound protein 2 17GRIA1 glutamate receptor, ionotropic, AMPA 1 5GRIA2 glutamate receptor, ionotropic, AMPA 2 4GRIA3 glutamate receptor, ionotropic, AMPA 3 XGRID1 glutamate receptor, ionotropic, delta 1 10GRIK2 glutamate receptor, ionotropic, kainate 2 6GRIK5 glutamate receptor, ionotropic, kainate 5 19GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 9GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 16GRM1 glutamate receptor, metabotropic 1 6GRM3 glutamate receptor, metabotropic 3 7GRM4 glutamate receptor, metabotropic 4 6GRM5 glutamate receptor, metabotropic 5 11GRM7 glutamate receptor, metabotropic 7 3GRM8 glutamate receptor, metabotropic 8 7GSK3B glycogen synthase kinase 3 beta 3GSPT1 G1 to S phase transition 1 16GSPT2 G1 to S phase transition 2 XGSR glutathione reductase 8

GSS glutathione synthetase 20GSTA4 glutathione S-transferase alpha 4 6GSTM4 glutathione S-transferase mu 4 1GUCA1A guanylate cyclase activator 1A (retina) 6GUCY1A2 guanylate cyclase 1, soluble, alpha 2 11GUCY1A3 guanylate cyclase 1, soluble, alpha 3 4GUCY1B3 guanylate cyclase 1, soluble, beta 3 4GUK1 guanylate kinase 1 1H2AFJ H2A histone family, member J 12H2AFZ H2A histone family, member Z 4HABP4 hyaluronan binding protein 4 9HACE1 HECT domain and ankyrin repeat containing E3 ubiquitin p 6HAGHL hydroxyacylglutathione hydrolase-like 16HARS histidyl-tRNA synthetase 5HAS1 hyaluronan synthase 1 19HAX1 HCLS1 associated protein X-1 1HCCS holocytochrome c synthase XHCN2 hyperpolarization activated cyclic nucleotide gated potas 19HDAC2 histone deacetylase 2 6HDAC8 histone deacetylase 8 XHDLBP high density lipoprotein binding protein 2HECTD2 HECT domain containing E3 ubiquitin protein ligase 2 10HERC1 HECT and RLD domain containing E3 ubiquitin protein lig 15HERC3 HECT and RLD domain containing E3 ubiquitin protein liga 4HES4 hes family bHLH transcription factor 4 1HEY1 hes-related family bHLH transcription factor with YRPW m 8HIATL2 hippocampus abundant transcript-like 2 9HIC2 hypermethylated in cancer 2 22HINT1 histidine triad nucleotide binding protein 1 5HIST3H2A histone cluster 3, H2a 1HIVEP2 human immunodeficiency virus type I enhancer binding pr 6HLF hepatic leukemia factor 17HMGA1 high mobility group AT-hook 1 6HMGCLL1 3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1 6HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 5HMOX2 heme oxygenase (decycling) 2 16HN1 hematological and neurological expressed 1 17HOMER1 homer scaffolding protein 1 5HPCA hippocalcin 1HPCAL4 hippocalcin like 4 1HPRT1 hypoxanthine phosphoribosyltransferase 1 XHRAS Harvey rat sarcoma viral oncogene homolog 11HRASLS HRAS-like suppressor 3HRH3 histamine receptor H3 20HS2ST1 heparan sulfate 2-O-sulfotransferase 1 1HS3ST4 heparan sulfate (glucosamine) 3-O-sulfotransferase 4 16HS3ST5 heparan sulfate (glucosamine) 3-O-sulfotransferase 5 6HS6ST2 heparan sulfate 6-O-sulfotransferase 2 X

HS6ST3 heparan sulfate 6-O-sulfotransferase 3 13HSFY1 heat shock transcription factor, Y-linked 1 YHSFY2 heat shock transcription factor, Y linked 2 YHSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic co 19HSPH1 heat shock 105kDa/110kDa protein 1 13HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein- 1HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein- 6HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein- 13HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein- XHTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-co 5HTR5A 5-hydroxytryptamine (serotonin) receptor 5A, G protein- 7HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-co 1HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cy 10HYOU1 hypoxia up-regulated 1 11IARS isoleucyl-tRNA synthetase 9IBSP integrin-binding sialoprotein 4ICA1 islet cell autoantigen 1, 69kDa 7ICAM5 intercellular adhesion molecule 5, telencephalin 19ICMT isoprenylcysteine carboxyl methyltransferase 1IDH3A isocitrate dehydrogenase 3 (NAD+) alpha 15IDH3G isocitrate dehydrogenase 3 (NAD+) gamma XIDS iduronate 2-sulfatase XIFNGR2 interferon gamma receptor 2 (interferon gamma transduc 21IGSF3 immunoglobulin superfamily, member 3 1IL7 interleukin 7 8IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1 7IMPG1 interphotoreceptor matrix proteoglycan 1 6INA internexin neuronal intermediate filament protein, alpha 10INHA inhibin, alpha 2INHBA inhibin, beta A 7INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa 2INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 4INPP5A inositol polyphosphate-5-phosphatase, 40kDa 10INSM1 insulinoma-associated 1 20INSM2 insulinoma-associated 2 14ITGAE integrin, alpha E (antigen CD103, human mucosal lymphoc 17ITPA inosine triphosphatase (nucleoside triphosphate pyropho 20ITPKA inositol-trisphosphate 3-kinase A 15ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 3IVNS1ABP influenza virus NS1A binding protein 1JAZF1 JAZF zinc finger 1 7JPH1 junctophilin 1 8JPH3 junctophilin 3 16JPH4 junctophilin 4 14KATNB1 katanin p80 (WD repeat containing) subunit B 1 16KBTBD2 kelch repeat and BTB (POZ) domain containing 2 7KCNA1 potassium channel, voltage gated shaker related subfami 12KCNA2 potassium channel, voltage gated shaker related subfami 1

KCNA4 potassium channel, voltage gated shaker related subfami 11KCNAB2 potassium channel, voltage gated subfamily A regulatory 1KCNB1 potassium channel, voltage gated Shab related subfamily 20KCNC1 potassium channel, voltage gated Shaw related subfamil 11KCNC3 potassium channel, voltage gated Shaw related subfamil 19KCND2 potassium channel, voltage gated Shal related subfamily 7KCNF1 potassium channel, voltage gated modifier subfamily F, 2KCNH2 potassium channel, voltage gated eag related subfamily 7KCNH3 potassium channel, voltage gated eag related subfamily 12KCNH4 potassium channel, voltage gated eag related subfamily 17KCNIP1 Kv channel interacting protein 1 5KCNIP2 Kv channel interacting protein 2 10KCNIP4 Kv channel interacting protein 4 4KCNJ4 potassium channel, inwardly rectifying subfamily J, memb 22KCNK1 potassium channel, two pore domain subfamily K, membe 1KCNK2 potassium channel, two pore domain subfamily K, membe 1KCNK4 potassium channel, two pore domain subfamily K, membe 11KCNMA1 potassium channel, calcium activated large conductance 10KCNN1 potassium channel, calcium activated intermediate/smal 19KCNQ2 potassium channel, voltage gated KQT-like subfamily Q, 20KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, 8KCNQ5 potassium channel, voltage gated KQT-like subfamily Q, 6KCNS2 potassium voltage-gated channel, modifier subfamily S, 8KCNV1 potassium channel, voltage gated modifier subfamily V, 8KCTD1 potassium channel tetramerization domain containing 1 18KCTD16 potassium channel tetramerization domain containing 16 5KCTD4 potassium channel tetramerization domain containing 4 13KIAA0232 KIAA0232 4KIAA0368 KIAA0368 9KIAA0408 KIAA0408 6KIAA0513 KIAA0513 16KIAA0922 KIAA0922 4KIAA1045 KIAA1045 9KIAA1107 KIAA1107 1KIAA1217 KIAA1217 10KIAA1324 KIAA1324 1KIAA1462 KIAA1462 10KIAA1467 KIAA1467 12KIAA1468 KIAA1468 18KIAA2022 KIAA2022 XKIF3B kinesin family member 3B 20KIF3C kinesin family member 3C 2KIF5A kinesin family member 5A 12KIF5C kinesin family member 5C 2KIFAP3 kinesin-associated protein 3 1KIFC2 kinesin family member C2 8KIN Kin17 DNA and RNA binding protein 10KIRREL3 kin of IRRE like 3 (Drosophila) 11

KL klotho 13KLC2 kinesin light chain 2 11KLF16 Kruppel-like factor 16 19KLF5 Kruppel-like factor 5 (intestinal) 13KLHL1 kelch-like family member 1 13KLHL13 kelch-like family member 13 XKLHL2 kelch-like family member 2 4KLHL7 kelch-like family member 7 7KREMEN1 kringle containing transmembrane protein 1 22KRTAP2-2 keratin associated protein 2-2 17KRTAP3-2 keratin associated protein 3-2 17KRTAP4-2 keratin associated protein 4-2 17KRTAP4-4 keratin associated protein 4-4 17L1CAM L1 cell adhesion molecule XL3MBTL2 l(3)mbt-like 2 (Drosophila) 22LAMB1 laminin, beta 1 7LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial) 2LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial) 7LARGE like-glycosyltransferase 22LCMT1 leucine carboxyl methyltransferase 1 16LDB2 LIM domain binding 2 4LDHA lactate dehydrogenase A 11LDOC1 leucine zipper, down-regulated in cancer 1 XLECT1 leukocyte cell derived chemotaxin 1 13LGALS8 lectin, galactoside-binding, soluble, 8 1LGI1 leucine-rich, glioma inactivated 1 10LHFPL3 lipoma HMGIC fusion partner-like 3 7LIG4 ligase IV, DNA, ATP-dependent 13LIN7B lin-7 homolog B (C. elegans) 19LMAN1L lectin, mannose-binding, 1 like 15LMO4 LIM domain only 4 1LMO7 LIM domain 7 13LMTK2 lemur tyrosine kinase 2 7LPIN2 lipin 2 18LPL lipoprotein lipase 8LRFN5 leucine rich repeat and fibronectin type III domain contai 14LRP11 low density lipoprotein receptor-related protein 11 6LRP3 low density lipoprotein receptor-related protein 3 19LRPPRC leucine-rich pentatricopeptide repeat containing 2LRRC4 leucine rich repeat containing 4 7LRRN3 leucine rich repeat neuronal 3 7LRRTM1 leucine rich repeat transmembrane neuronal 1 2LSM10 LSM10, U7 small nuclear RNA associated 1LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevi 19LY6E lymphocyte antigen 6 complex, locus E 8LYNX1 Ly6/neurotoxin 1 8LZTS1 leucine zipper, putative tumor suppressor 1 8MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) 7

MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 4MAGED1 melanoma antigen family D1 XMAGEL2 melanoma antigen family L2 15MAL2 mal, T-cell differentiation protein 2 (gene/pseudogene) 8MAN1A1 mannosidase, alpha, class 1A, member 1 6MAP1A microtubule-associated protein 1A 15MAP1B microtubule-associated protein 1B 5MAP2 microtubule-associated protein 2 2MAP2K1 mitogen-activated protein kinase kinase 1 15MAP2K2 mitogen-activated protein kinase kinase 2 19MAP2K4 mitogen-activated protein kinase kinase 4 17MAP2K5 mitogen-activated protein kinase kinase 5 15MAP3K10 mitogen-activated protein kinase kinase kinase 10 19MAP3K13 mitogen-activated protein kinase kinase kinase 13 3MAP6 microtubule-associated protein 6 11MAPK1 mitogen-activated protein kinase 1 22MAPK3 mitogen-activated protein kinase 3 16MAPK6 mitogen-activated protein kinase 6 15MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2 22MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3 16MAPK9 mitogen-activated protein kinase 9 5MAPKAP1 mitogen-activated protein kinase associated protein 1 9MAPRE2 microtubule-associated protein, RP/EB family, member 2 18MAPRE3 microtubule-associated protein, RP/EB family, member 3 2MARK1 MAP/microtubule affinity-regulating kinase 1 1MARK2 MAP/microtubule affinity-regulating kinase 2 11MARK4 MAP/microtubule affinity-regulating kinase 4 19MARS methionyl-tRNA synthetase 12MATK megakaryocyte-associated tyrosine kinase 19MATR3 matrin 3 5MATR3 matrin 3 5MAZ MYC-associated zinc finger protein (purine-binding transcr 16MBNL2 muscleblind-like splicing regulator 2 13MBTPS1 membrane-bound transcription factor peptidase, site 1 16MCF2 MCF.2 cell line derived transforming sequence XMCM4 minichromosome maintenance complex component 4 8MDH1 malate dehydrogenase 1, NAD (soluble) 2MDH2 malate dehydrogenase 2, NAD (mitochondrial) 7MDK midkine (neurite growth-promoting factor 2) 11ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial 18ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial 11MECP2 methyl CpG binding protein 2 XMEF2B myocyte enhancer factor 2B 19MEF2D myocyte enhancer factor 2D 1MEIS2 Meis homeobox 2 15MEN1 multiple endocrine neoplasia I 11MESDC1 mesoderm development candidate 1 15METAP1 methionyl aminopeptidase 1 4

MGAT5B mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glu 17MGST3 microsomal glutathione S-transferase 3 1MIF macrophage migration inhibitory factor (glycosylation-inhi 22MKKS McKusick-Kaufman syndrome 20MLF2 myeloid leukemia factor 2 12MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax ho 9MMAA methylmalonic aciduria (cobalamin deficiency) cblA type 4MMD monocyte to macrophage differentiation-associated 17MME membrane metallo-endopeptidase 3MMP17 matrix metallopeptidase 17 (membrane-inserted) 12MMP24 matrix metallopeptidase 24 (membrane-inserted) 20MN1 meningioma (disrupted in balanced translocation) 1 22MOAP1 modulator of apoptosis 1 14MOCS2 molybdenum cofactor synthesis 2 5MPHOSPH6 M-phase phosphoprotein 6 16MPP1 membrane protein, palmitoylated 1, 55kDa XMPP5 membrane protein, palmitoylated 5 (MAGUK p55 subfami 14MPP7 membrane protein, palmitoylated 7 (MAGUK p55 subfami 10MPPE1 metallophosphoesterase 1 18MRPL14 mitochondrial ribosomal protein L14 6MRPL15 mitochondrial ribosomal protein L15 8MRPL17 mitochondrial ribosomal protein L17 11MRPL21 mitochondrial ribosomal protein L21 11MRPL3 mitochondrial ribosomal protein L3 3MRPL32 mitochondrial ribosomal protein L32 7MRPL33 mitochondrial ribosomal protein L33 2MRPL34 mitochondrial ribosomal protein L34 19MRPL35 mitochondrial ribosomal protein L35 2MRPL4 mitochondrial ribosomal protein L4 19MRPL41 mitochondrial ribosomal protein L41 9MRPS15 mitochondrial ribosomal protein S15 1MRPS18C mitochondrial ribosomal protein S18C 4MRPS22 mitochondrial ribosomal protein S22 3MRPS25 mitochondrial ribosomal protein S25 3MRPS33 mitochondrial ribosomal protein S33 7MSH2 mutS homolog 2 2MSH3 mutS homolog 3 5MTA1 metastasis associated 1 14MTA3 metastasis associated 1 family, member 3 2MTCP1 mature T-cell proliferation 1 XMTFMT mitochondrial methionyl-tRNA formyltransferase 15MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ depende 14MTMR6 myotubularin related protein 6 13MTPN myotrophin 7MTX1 metaxin 1 1MTX2 metaxin 2 2MUC20 mucin 20, cell surface associated 3MYEF2 myelin expression factor 2 15

MYH10 myosin, heavy chain 10, non-muscle 17MYH7 myosin, heavy chain 7, cardiac muscle, beta 14MYO5A myosin VA (heavy chain 12, myoxin) 15MYT1L myelin transcription factor 1-like 2NAP1L2 nucleosome assembly protein 1-like 2 XNAP1L3 nucleosome assembly protein 1-like 3 XNAP1L5 nucleosome assembly protein 1-like 5 4NAPA N-ethylmaleimide-sensitive factor attachment protein, al 19NAPB N-ethylmaleimide-sensitive factor attachment protein, be 20NBEA neurobeachin 13NCDN neurochondrin 1NCKAP1 NCK-associated protein 1 2NDFIP1 Nedd4 family interacting protein 1 5NDFIP2 Nedd4 family interacting protein 2 13NDN necdin, melanoma antigen (MAGE) family member 15NDNL2 necdin-like 2 15NDRG3 NDRG family member 3 20NDRG4 NDRG family member 4 16NDST3 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4NDUFA1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1XNDUFA3 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3 19NDUFA4 NDUFA4, mitochondrial complex associated 7NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7NDUFA7 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7 19NDUFA8 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9NDUFAB1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomp 16NDUFB1 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1 14NDUFB10 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1 16NDUFB2 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2 7NDUFB4 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4 3NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5 3NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6 9NDUFB8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8 10NDUFC2 NADH dehydrogenase (ubiquinone) 1, subcomplex unknow 11NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kD 2NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kD 11NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kD 5NDUFS5 NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kD 1NDUFV2 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa 18NEDD4L neural precursor cell expressed, developmentally down-reg 18NEDD8 neural precursor cell expressed, developmentally down-r 14NEFH neurofilament, heavy polypeptide 22NEFL neurofilament, light polypeptide 8NEGR1 neuronal growth regulator 1 1NELL2 NEL-like 2 (chicken) 12NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 16NEU1 sialidase 1 (lysosomal sialidase) 6NF1 neurofibromin 1 17

NFRKB nuclear factor related to kappaB binding protein 11NFYC nuclear transcription factor Y, gamma 1NGEF neuronal guanine nucleotide exchange factor 2NGFRAP1 nerve growth factor receptor (TNFRSF16) associated proteXNHLH1 nescient helix loop helix 1 1NHP2L1 NHP2 non-histone chromosome protein 2-like 1 (S. cerevis 22NIF3L1 NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae) 2NIPSNAP1 nipsnap homolog 1 (C. elegans) 22NIPSNAP3B nipsnap homolog 3B (C. elegans) 9NISCH nischarin 3NIT2 nitrilase family, member 2 3NKIRAS1 NFKB inhibitor interacting Ras-like 1 3NLGN1 neuroligin 1 3NLGN2 neuroligin 2 17NLGN3 neuroligin 3 XNLK nemo-like kinase 17NME1 NME/NM23 nucleoside diphosphate kinase 1 17NNAT neuronatin 20NNT nicotinamide nucleotide transhydrogenase 5NOG noggin 17NOL4 nucleolar protein 4 18NOL6 nucleolar protein 6 (RNA-associated) 9NOS1 nitric oxide synthase 1 (neuronal) 12NOVA2 neuro-oncological ventral antigen 2 19NPAS2 neuronal PAS domain protein 2 2NPHP4 nephronophthisis 4 1NPM2 nucleophosmin/nucleoplasmin 2 8NPTX1 neuronal pentraxin I 17NPY1R neuropeptide Y receptor Y1 4NPY5R neuropeptide Y receptor Y5 4NQO1 NAD(P)H dehydrogenase, quinone 1 16NRG1 neuregulin 1 8NRGN neurogranin (protein kinase C substrate, RC3) 11NRIP3 nuclear receptor interacting protein 3 11NRXN1 neurexin 1 2NRXN2 neurexin 2 11NRXN3 neurexin 3 14NSF N-ethylmaleimide-sensitive factor 17NTNG1 netrin G1 1NTRK3 neurotrophic tyrosine kinase, receptor, type 3 15NUCB2 nucleobindin 2 11NUDT10 nudix (nucleoside diphosphate linked moiety X)-type motiXNUDT11 nudix (nucleoside diphosphate linked moiety X)-type motiXNUDT4 nudix (nucleoside diphosphate linked moiety X)-type moti 12NUP50 nucleoporin 50kDa 22OAZ1 ornithine decarboxylase antizyme 1 19OBSCN obscurin, cytoskeletal calmodulin and titin-interacting R 1OCRL oculocerebrorenal syndrome of Lowe X

OGT O-linked N-acetylglucosamine (GlcNAc) transferase XOLFM1 olfactomedin 1 9OLFM2 olfactomedin 2 19OMG oligodendrocyte myelin glycoprotein 17OPA1 optic atrophy 1 (autosomal dominant) 3OPCML opioid binding protein/cell adhesion molecule-like 11OPN4 opsin 4 10OPRK1 opioid receptor, kappa 1 8OPRL1 opiate receptor-like 1 20OSBP2 oxysterol binding protein 2 22OSBPL10 oxysterol binding protein-like 10 3OSBPL8 oxysterol binding protein-like 8 12OTOF otoferlin 2P2RX5 purinergic receptor P2X, ligand gated ion channel, 5 17PACSIN1 protein kinase C and casein kinase substrate in neurons 1 6PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory 17PAIP1 poly(A) binding protein interacting protein 1 5PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 11PAK3 p21 protein (Cdc42/Rac)-activated kinase 3 XPAK6 p21 protein (Cdc42/Rac)-activated kinase 6 15PAK7 p21 protein (Cdc42/Rac)-activated kinase 7 20PALM paralemmin 19PAM peptidylglycine alpha-amidating monooxygenase 5PANK4 pantothenate kinase 4 1PANX1 pannexin 1 11PANX2 pannexin 2 22PARD6A par-6 family cell polarity regulator alpha 16PARK2 parkin RBR E3 ubiquitin protein ligase 6PARVG parvin, gamma 22PASK PAS domain containing serine/threonine kinase 2PBX3 pre-B-cell leukemia homeobox 3 9PCDH10 protocadherin 10 4PCDH11X protocadherin 11 X-linked XPCDH11Y protocadherin 11 Y-linked YPCDH20 protocadherin 20 13PCDH20 protocadherin 20 13PCDH7 protocadherin 7 4PCDH8 protocadherin 8 13PCDHA12 protocadherin alpha 12 5PCDHA6 protocadherin alpha 6 5PCDHAC2 protocadherin alpha subfamily C, 2 5PCDHB10 protocadherin beta 10 5PCDHB3 protocadherin beta 3 5PCDHGC5 protocadherin gamma subfamily C, 5 5PCLO piccolo presynaptic cytomatrix protein 7PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase 6PCP4 Purkinje cell protein 4 21PCSK1 proprotein convertase subtilisin/kexin type 1 5

PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor XPCSK2 proprotein convertase subtilisin/kexin type 2 20PDE10A phosphodiesterase 10A 6PDE1B phosphodiesterase 1B, calmodulin-dependent 12PDE2A phosphodiesterase 2A, cGMP-stimulated 11PDE4A phosphodiesterase 4A, cAMP-specific 19PDE4D phosphodiesterase 4D, cAMP-specific 5PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta 2PDE7B phosphodiesterase 7B 6PDE8B phosphodiesterase 8B 5PDF peptide deformylase (mitochondrial) 16PDHB pyruvate dehydrogenase (lipoamide) beta 3PDK2 pyruvate dehydrogenase kinase, isozyme 2 17PDPK1 3-phosphoinositide dependent protein kinase 1 16PDX1 pancreatic and duodenal homeobox 1 13PDXP pyridoxal (pyridoxine, vitamin B6) phosphatase 22PDYN prodynorphin 20PEG10 paternally expressed 10 7PEG3 paternally expressed 3 19PELI1 pellino E3 ubiquitin protein ligase 1 2PENK proenkephalin 8PEX11B peroxisomal biogenesis factor 11 beta 1PEX14 peroxisomal biogenesis factor 14 1PFDN1 prefoldin subunit 1 5PFKM phosphofructokinase, muscle 12PFN2 profilin 2 3PGAM1 phosphoglycerate mutase 1 (brain) 10PGBD5 piggyBac transposable element derived 5 1PGM2L1 phosphoglucomutase 2-like 1 11PGRMC1 progesterone receptor membrane component 1 XPHACTR1 phosphatase and actin regulator 1 6PHLDA1 pleckstrin homology-like domain, family A, member 1 12PHYHIP phytanoyl-CoA 2-hydroxylase interacting protein 8PIGB phosphatidylinositol glycan anchor biosynthesis, class B 15PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic 3PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 19PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 19PINK1 PTEN induced putative kinase 1 1PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamm 19PISD phosphatidylserine decarboxylase 22PITPNM2 phosphatidylinositol transfer protein, membrane-associat 12PJA1 praja ring finger 1, E3 ubiquitin protein ligase XPKIA protein kinase (cAMP-dependent, catalytic) inhibitor alph 8PKP2 plakophilin 2 12PLA2G12B phospholipase A2, group XIIB 10PLAA phospholipase A2-activating protein 9PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 20PLCL2 phospholipase C-like 2 3

PLD3 phospholipase D family, member 3 19PLEK pleckstrin 2PLEKHA2 pleckstrin homology domain containing, family A (phospho 8PLXNA2 plexin A2 1PLXNA4 plexin A4 7PNMA2 paraneoplastic Ma antigen 2 8POLB polymerase (DNA directed), beta 8POLE4 polymerase (DNA-directed), epsilon 4, accessory subunit 2POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa 19POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa 8POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 16POU3F1 POU class 3 homeobox 1 1PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide 19PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide 1PPIA peptidylprolyl isomerase A (cyclophilin A) 7PPIH peptidylprolyl isomerase H (cyclophilin H) 1PPIL1 peptidylprolyl isomerase (cyclophilin)-like 1 6PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A 14PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme 11PPP1R11 protein phosphatase 1, regulatory (inhibitor) subunit 11 6PPP1R12C protein phosphatase 1, regulatory subunit 12C 19PPP1R13B protein phosphatase 1, regulatory subunit 13B 14PPP1R16B protein phosphatase 1, regulatory subunit 16B 20PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A 12PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B 17PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2 3PPP1R7 protein phosphatase 1, regulatory subunit 7 2PPP1R9A protein phosphatase 1, regulatory subunit 9A 7PPP1R9B protein phosphatase 1, regulatory subunit 9B 17PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme 5PPP2R1A protein phosphatase 2, regulatory subunit A, alpha 19PPP2R2A protein phosphatase 2, regulatory subunit B, alpha 8PPP2R2B protein phosphatase 2, regulatory subunit B, beta 5PPP2R2C protein phosphatase 2, regulatory subunit B, gamma 4PPP2R2D protein phosphatase 2, regulatory subunit B, delta 10PPP2R5B protein phosphatase 2, regulatory subunit B', beta 11PPP2R5D protein phosphatase 2, regulatory subunit B', delta 6PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon iso 14PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 4PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme 10PPP3R1 protein phosphatase 3, regulatory subunit B, alpha 2PRH1 proline-rich protein HaeIII subfamily 1 12PRICKLE1 prickle homolog 1 (Drosophila) 12PRKACB protein kinase, cAMP-dependent, catalytic, beta 1PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic su 7PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta 7PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 7PRKCD protein kinase C, delta 3

PRKCE protein kinase C, epsilon 2PRKCG protein kinase C, gamma 19PRKCH protein kinase C, eta 14PRKCI protein kinase C, iota 3PRKCZ protein kinase C, zeta 1PRLR prolactin receptor 5PRNP prion protein 20PRPS2 phosphoribosyl pyrophosphate synthetase 2 XPRR3 proline rich 3 6PRSS3 protease, serine, 3 9PSD pleckstrin and Sec7 domain containing 10PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 11PSMB7 proteasome (prosome, macropain) subunit, beta type, 7 9PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3 11PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPa 2PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPa 17PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPa 17PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPa 19PSME3 proteasome (prosome, macropain) activator subunit 3 (P 17PTDSS1 phosphatidylserine synthase 1 8PTGES2 prostaglandin E synthase 2 9PTGIS prostaglandin I2 (prostacyclin) synthase 20PTK2B protein tyrosine kinase 2 beta 8PTPDC1 protein tyrosine phosphatase domain containing 1 9PTPN11 protein tyrosine phosphatase, non-receptor type 11 12PTPN4 protein tyrosine phosphatase, non-receptor type 4 (mega 2PTPN5 protein tyrosine phosphatase, non-receptor type 5 (stria 11PTPN7 protein tyrosine phosphatase, non-receptor type 7 1PTPRM protein tyrosine phosphatase, receptor type, M 18PTPRN protein tyrosine phosphatase, receptor type, N 2PTPRN2 protein tyrosine phosphatase, receptor type, N polypepti 7PTPRO protein tyrosine phosphatase, receptor type, O 12PTPRR protein tyrosine phosphatase, receptor type, R 12PTPRT protein tyrosine phosphatase, receptor type, T 20PTS 6-pyruvoyltetrahydropterin synthase 11PWP1 PWP1 homolog (S. cerevisiae) 12RAB11A RAB11A, member RAS oncogene family 15RAB11B RAB11B, member RAS oncogene family 19RAB26 RAB26, member RAS oncogene family 16RAB27B RAB27B, member RAS oncogene family 18RAB39B RAB39B, member RAS oncogene family XRAB3A RAB3A, member RAS oncogene family 19RAB3C RAB3C, member RAS oncogene family 5RAB40B RAB40B, member RAS oncogene family 17RAB40C RAB40C, member RAS oncogene family 16RAB4B RAB4B, member RAS oncogene family 19RAB6A RAB6A, member RAS oncogene family 11RAB6B RAB6B, member RAS oncogene family 3

RAB6C RAB6C, member RAS oncogene family 2RAB9B RAB9B, member RAS oncogene family XRABIF RAB interacting factor 1RAD1 RAD1 checkpoint DNA exonuclease 5RAD17 RAD17 homolog (S. pombe) 5RAD23B RAD23 homolog B (S. cerevisiae) 9RAD50 RAD50 homolog (S. cerevisiae) 5RAD51C RAD51 paralog C 17RAD54B RAD54 homolog B (S. cerevisiae) 8RALB v-ral simian leukemia viral oncogene homolog B 2RALGPS2 Ral GEF with PH domain and SH3 binding motif 2 1RAN RAN, member RAS oncogene family 12RANBP2 RAN binding protein 2 2RANGAP1 Ran GTPase activating protein 1 22RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1 4RAP2A RAP2A, member of RAS oncogene family 13RAP2B RAP2B, member of RAS oncogene family 3RARB retinoic acid receptor, beta 3RASAL1 RAS protein activator like 1 (GAP1 like) 12RASAL2 RAS protein activator like 2 1RASD2 RASD family, member 2 22RASGEF1A RasGEF domain family, member 1A 10RASGEF1B RasGEF domain family, member 1B 4RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1 15RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulate 15RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulate 11RASL10B RAS-like, family 10, member B 17RBBP7 retinoblastoma binding protein 7 XRBM20 RNA binding motif protein 20 10RBM24 RNA binding motif protein 24 6RBMS1 RNA binding motif, single stranded interacting protein 1 2RBP4 retinol binding protein 4, plasma 10RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubi 4RCN1 reticulocalbin 1, EF-hand calcium binding domain 11RDH10 retinol dehydrogenase 10 (all-trans) 8RDH12 retinol dehydrogenase 12 (all-trans/9-cis/11-cis) 14REPS2 RALBP1 associated Eps domain containing 2 XRERG RAS-like, estrogen-regulated, growth inhibitor 12RFPL3S RFPL3 antisense 22RGS12 regulator of G-protein signaling 12 4RGS14 regulator of G-protein signaling 14 5RGS17 regulator of G-protein signaling 17 6RGS2 regulator of G-protein signaling 2 1RGS20 regulator of G-protein signaling 20 8RGS4 regulator of G-protein signaling 4 1RGS7 regulator of G-protein signaling 7 1RGS8 regulator of G-protein signaling 8 1RGS9 regulator of G-protein signaling 9 17

RHOBTB2 Rho-related BTB domain containing 2 8RIMS1 regulating synaptic membrane exocytosis 1 6RIMS2 regulating synaptic membrane exocytosis 2 8RIMS4 regulating synaptic membrane exocytosis 4 20RIT2 Ras-like without CAAX 2 18RNF10 ring finger protein 10 12RNF123 ring finger protein 123 3RNF150 ring finger protein 150 4RNF157 ring finger protein 157 17RNF2 ring finger protein 2 1RNF6 ring finger protein (C3H2C3 type) 6 13RNF7 ring finger protein 7 3RNMT RNA (guanine-7-) methyltransferase 18ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosoph 3ROCK2 Rho-associated, coiled-coil containing protein kinase 2 2RPA3 replication protein A3, 14kDa 7RPE ribulose-5-phosphate-3-epimerase 2RPF1 ribosome production factor 1 homolog (S. cerevisiae) 1RPH3A rabphilin 3A 12RPL14 ribosomal protein L14 3RPL15 ribosomal protein L15 3RPL31 ribosomal protein L31 2RPL35A ribosomal protein L35a 3RPL4 ribosomal protein L4 15RPP14 ribonuclease P/MRP 14kDa subunit 3RPP40 ribonuclease P/MRP 40kDa subunit 6RPS27 ribosomal protein S27 1RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 XRPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4 11RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5 14RRN3 RRN3 RNA polymerase I transcription factor homolog (S. c 16RS1 retinoschisin 1 XRTN1 reticulon 1 14RTN2 reticulon 2 19RTN4 reticulon 4 2RTTN rotatin 18RUNDC1 RUN domain containing 1 17RUSC1 RUN and SH3 domain containing 1 1RUVBL1 RuvB-like AAA ATPase 1 3RXRB retinoid X receptor, beta 6RXRG retinoid X receptor, gamma 1RYR2 ryanodine receptor 2 (cardiac) 1RYR3 ryanodine receptor 3 15SACS sacsin molecular chaperone 13SBF1 SET binding factor 1 22SCAMP1 secretory carrier membrane protein 1 5SCAMP5 secretory carrier membrane protein 5 15SCARB1 scavenger receptor class B, member 1 12

SCG2 secretogranin II 2SCG3 secretogranin III 15SCN1A sodium channel, voltage gated, type I alpha subunit 2SCN1B sodium channel, voltage gated, type I beta subunit 19SCN2B sodium channel, voltage gated, type II beta subunit 11SCN3A sodium channel, voltage gated, type III alpha subunit 2SCN4B sodium channel, voltage gated, type IV beta subunit 11SCN8A sodium channel, voltage gated, type VIII alpha subunit 12SCOC short coiled-coil protein 4SCRT1 scratch family zinc finger 1 8SDCBP syndecan binding protein (syntenin) 8SDCBP2 syndecan binding protein (syntenin) 2 20SDHB succinate dehydrogenase complex, subunit B, iron sulfur ( 1SEC14L1 SEC14-like 1 (S. cerevisiae) 17SEC23A Sec23 homolog A (S. cerevisiae) 14SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae) 10SEMA3A sema domain, immunoglobulin domain (Ig), short basic d 7SEMA6B sema domain, transmembrane domain (TM), and cytoplas 19SENP2 SUMO1/sentrin/SMT3 specific peptidase 2 3SERF1A small EDRK-rich factor 1A (telomeric) 5SERF1B small EDRK-rich factor 1B (centromeric) 5SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 3SERTAD4 SERTA domain containing 4 1SESN3 sestrin 3 11SEZ6 seizure related 6 homolog (mouse) 17SEZ6L seizure related 6 homolog (mouse)-like 22SF3B3 splicing factor 3b, subunit 3, 130kDa 16SFXN1 sideroflexin 1 5SGPP2 sphingosine-1-phosphate phosphatase 2 2SH3BP5 SH3-domain binding protein 5 (BTK-associated) 3SH3GL2 SH3-domain GRB2-like 2 9SH3RF2 SH3 domain containing ring finger 2 5SHANK2 SH3 and multiple ankyrin repeat domains 2 11SHC3 SHC (Src homology 2 domain containing) transforming pro 9SIAH2 siah E3 ubiquitin protein ligase 2 3SIN3B SIN3 transcription regulator family member B 19SIRT3 sirtuin 3 11SIX3 SIX homeobox 3 2SLBP stem-loop binding protein 4SLC12A5 solute carrier family 12 (potassium/chloride transporter) 20SLC12A6 solute carrier family 12 (potassium/chloride transporter) 15SLC13A5 solute carrier family 13 (sodium-dependent citrate trans 17SLC16A10 solute carrier family 16 (aromatic amino acid transporte 6SLC16A14 solute carrier family 16, member 14 2SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity 9SLC1A4 solute carrier family 1 (glutamate/neutral amino acid tr 2SLC1A6 solute carrier family 1 (high affinity aspartate/glutamate 19SLC24A3 solute carrier family 24 (sodium/potassium/calcium exch 20

SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutar 17SLC25A12 solute carrier family 25 (aspartate/glutamate carrier), m 2SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), m XSLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine 13SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamat 11SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphat 19SLC25A25 solute carrier family 25 (mitochondrial carrier; phosphat 9SLC25A27 solute carrier family 25, member 27 6SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate 12SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine 4SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine XSLC26A8 solute carrier family 26 (anion exchanger), member 8 6SLC29A1 solute carrier family 29 (equilibrative nucleoside transpo 6SLC2A12 solute carrier family 2 (facilitated glucose transporter), 6SLC2A13 solute carrier family 2 (facilitated glucose transporter), 12SLC2A14 solute carrier family 2 (facilitated glucose transporter), 12SLC2A3 solute carrier family 2 (facilitated glucose transporter), 12SLC35D3 solute carrier family 35, member D3 6SLC35F1 solute carrier family 35, member F1 6SLC35F3 solute carrier family 35, member F3 1SLC35F4 solute carrier family 35, member F4 14SLC37A3 solute carrier family 37, member 3 7SLC3A1 solute carrier family 3 (amino acid transporter heavy cha 2SLC4A1AP solute carrier family 4 (anion exchanger), member 1, adap 2SLC4A3 solute carrier family 4 (anion exchanger), member 3 2SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporte 4SLC7A8 solute carrier family 7 (amino acid transporter light chai 14SLC8A1 solute carrier family 8 (sodium/calcium exchanger), mem 2SLC8A2 solute carrier family 8 (sodium/calcium exchanger), mem 19SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton 1SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton 16SLC9A6 solute carrier family 9, subfamily A (NHE6, cation proton XSLIT1 slit homolog 1 (Drosophila) 10SLIT2 slit homolog 2 (Drosophila) 4SLIT3 slit homolog 3 (Drosophila) 5SLITRK2 SLIT and NTRK-like family, member 2 XSLITRK4 SLIT and NTRK-like family, member 4 XSLITRK6 SLIT and NTRK-like family, member 6 13SLK STE20-like kinase 10SLMAP sarcolemma associated protein 3SMARCA2 SWI/SNF related, matrix associated, actin dependent regu 9SMARCA4 SWI/SNF related, matrix associated, actin dependent regu 19SMARCD3 SWI/SNF related, matrix associated, actin dependent reg 7SMARCE1 SWI/SNF related, matrix associated, actin dependent regu 17SMOC2 SPARC related modular calcium binding 2 6SMURF1 SMAD specific E3 ubiquitin protein ligase 1 7SNAP25 synaptosomal-associated protein, 25kDa 20SNAP91 synaptosomal-associated protein, 91kDa 6

SNAPC5 small nuclear RNA activating complex, polypeptide 5, 19k 15SNCA synuclein, alpha (non A4 component of amyloid precursor 4SNCAIP synuclein, alpha interacting protein 5SNCB synuclein, beta 5SNN stannin 16SNPH syntaphilin 20SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa 19SNTG1 syntrophin, gamma 1 8SNURF SNRPN upstream reading frame 15SNURF SNRPN upstream reading frame 15SNX10 sorting nexin 10 7SNX15 sorting nexin 15 11SNX25 sorting nexin 25 4SNX27 sorting nexin family member 27 1SOGA3 SOGA family member 3 6SOGA3 SOGA family member 3 6SORCS1 sortilin-related VPS10 domain containing receptor 1 10SORCS3 sortilin-related VPS10 domain containing receptor 3 10SOX11 SRY (sex determining region Y)-box 11 2SPATS2 spermatogenesis associated, serine-rich 2 12SPINT2 serine peptidase inhibitor, Kunitz type, 2 19SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglyc 10SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglyc 4SPRED1 sprouty-related, EVH1 domain containing 1 15SPTB spectrin, beta, erythrocytic 14SPTBN2 spectrin, beta, non-erythrocytic 2 11SPTBN4 spectrin, beta, non-erythrocytic 4 19SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 5SREBF2 sterol regulatory element binding transcription factor 2 22SRM spermidine synthase 1SRPK1 SRSF protein kinase 1 6SRPR signal recognition particle receptor (docking protein) 11SS18L2 synovial sarcoma translocation gene on chromosome 18-l 3SSBP4 single stranded DNA binding protein 4 19SSTR1 somatostatin receptor 1 14SSTR2 somatostatin receptor 2 17SSX2IP synovial sarcoma, X breakpoint 2 interacting protein 1ST7 suppression of tumorigenicity 7 7STAR steroidogenic acute regulatory protein 8STARD4 StAR-related lipid transfer (START) domain containing 4 5STAT4 signal transducer and activator of transcription 4 2STAU2 staufen double-stranded RNA binding protein 2 8STEAP2 STEAP family member 2, metalloreductase 7STIM1 stromal interaction molecule 1 11STK11 serine/threonine kinase 11 19STK17A serine/threonine kinase 17a 7STK24 serine/threonine kinase 24 13STK25 serine/threonine kinase 25 2

STK32C serine/threonine kinase 32C 10STMN2 stathmin 2 8STMN3 stathmin-like 3 20STOML1 stomatin (EPB72)-like 1 15STRBP spermatid perinuclear RNA binding protein 9STRN striatin, calmodulin binding protein 2STRN4 striatin, calmodulin binding protein 4 19STS steroid sulfatase (microsomal), isozyme S XSTX1A syntaxin 1A (brain) 7STXBP1 syntaxin binding protein 1 9STXBP6 syntaxin binding protein 6 (amisyn) 14SUCLA2 succinate-CoA ligase, ADP-forming, beta subunit 13SUGT1 SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae) 13SULT4A1 sulfotransferase family 4A, member 1 22SUSD1 sushi domain containing 1 9SV2A synaptic vesicle glycoprotein 2A 1SV2B synaptic vesicle glycoprotein 2B 15SYN1 synapsin I XSYN2 synapsin II 3SYNGAP1 synaptic Ras GTPase activating protein 1 6SYNGR1 synaptogyrin 1 22SYNGR3 synaptogyrin 3 16SYNJ1 synaptojanin 1 21SYNPO synaptopodin 5SYNPR synaptoporin 3SYP synaptophysin XSYT1 synaptotagmin I 12SYT12 synaptotagmin XII 11SYT13 synaptotagmin XIII 11SYT3 synaptotagmin III 19SYT4 synaptotagmin IV 18SYT5 synaptotagmin V 19SYT6 synaptotagmin VI 1SYT7 synaptotagmin VII 11SYTL5 synaptotagmin-like 5 XTAC1 tachykinin, precursor 1 7TACC2 transforming, acidic coiled-coil containing protein 2 10TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP) 18TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor 11TAF9 TAF9 RNA polymerase II, TATA box binding protein (TBP)-a 5TAF9 TAF9 RNA polymerase II, TATA box binding protein (TBP)-a 5TBC1D16 TBC1 domain family, member 16 17TBC1D7 TBC1 domain family, member 7 6TBCD tubulin folding cofactor D 17TBRG1 transforming growth factor beta regulator 1 11TCEA2 transcription elongation factor A (SII), 2 20TCEB1 transcription elongation factor B (SIII), polypeptide 1 (15k 8TCP1 t-complex 1 6

TDRD5 tudor domain containing 5 1TDRD9 tudor domain containing 9 14TDRKH tudor and KH domain containing 1TEF thyrotrophic embryonic factor 22TERF2 telomeric repeat binding factor 2 16TERF2IP telomeric repeat binding factor 2, interacting protein 16TH tyrosine hydroxylase 11THOC3 THO complex 3 5THRB thyroid hormone receptor, beta 3THY1 Thy-1 cell surface antigen 11TIAM1 T-cell lymphoma invasion and metastasis 1 21TIAM2 T-cell lymphoma invasion and metastasis 2 6TIMM17A translocase of inner mitochondrial membrane 17 homolog 1TIMM17B translocase of inner mitochondrial membrane 17 homologXTIMM23 translocase of inner mitochondrial membrane 23 homolog 10TIMM50 translocase of inner mitochondrial membrane 50 homolog 19TIMM9 translocase of inner mitochondrial membrane 9 homolog 14TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Droso 9TLE4 transducin-like enhancer of split 4 9TLK1 tousled-like kinase 1 2TLL2 tolloid-like 2 10TLN2 talin 2 15TMEFF1 transmembrane protein with EGF-like and two follistatin- 9TMEFF2 transmembrane protein with EGF-like and two follistatin- 2TMEM25 transmembrane protein 25 11TMOD2 tropomodulin 2 (neuronal) 15TMSB10 thymosin beta 10 2TNFRSF8 tumor necrosis factor receptor superfamily, member 8 1TNNC2 troponin C type 2 (fast) 20TOLLIP toll interacting protein 11TOM1L1 target of myb1 (chicken)-like 1 17TOMM22 translocase of outer mitochondrial membrane 22 homolog 22TOMM34 translocase of outer mitochondrial membrane 34 20TOMM70A translocase of outer mitochondrial membrane 70 homolog 3TP53BP1 tumor protein p53 binding protein 1 15TPBG trophoblast glycoprotein 6TPCN2 two pore segment channel 2 11TPD52 tumor protein D52 8TPD52L1 tumor protein D52-like 1 6TPI1 triosephosphate isomerase 1 12TPM3 tropomyosin 3 1TPM4 tropomyosin 4 19TPMT thiopurine S-methyltransferase 6TRAF5 TNF receptor-associated factor 5 1TRAP1 TNF receptor-associated protein 1 16TRAPPC5 trafficking protein particle complex 5 19TRAPPC6B trafficking protein particle complex 6B 14TRERF1 transcriptional regulating factor 1 6

TRHDE thyrotropin-releasing hormone degrading enzyme 12TRIM11 tripartite motif containing 11 1TRIM3 tripartite motif containing 3 11TRIM37 tripartite motif containing 37 17TRIM46 tripartite motif containing 46 1TRIM48 tripartite motif containing 48 11TRIM9 tripartite motif containing 9 14TRIO trio Rho guanine nucleotide exchange factor 5TRUB1 TruB pseudouridine (psi) synthase family member 1 10TSC2 tuberous sclerosis 2 16TSSC1 tumor suppressing subtransferable candidate 1 2TTBK1 tau tubulin kinase 1 6TTC3 tetratricopeptide repeat domain 3 21TTYH3 tweety family member 3 7TUBB tubulin, beta class I 6TUSC3 tumor suppressor candidate 3 8UBE2D2 ubiquitin-conjugating enzyme E2D 2 5UBE2E2 ubiquitin-conjugating enzyme E2E 2 3UBE2G1 ubiquitin-conjugating enzyme E2G 1 17UBE2M ubiquitin-conjugating enzyme E2M 19UBE2N ubiquitin-conjugating enzyme E2N 12UBE2V2 ubiquitin-conjugating enzyme E2 variant 2 8UBL3 ubiquitin-like 3 13UBQLN2 ubiquilin 2 XUCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolest 4UCHL3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolest 13UGP2 UDP-glucose pyrophosphorylase 2 2ULK1 unc-51 like autophagy activating kinase 1 12UNC13A unc-13 homolog A (C. elegans) 19UNC5A unc-5 homolog A (C. elegans) 5UNC5D unc-5 homolog D (C. elegans) 8UPK1B uroplakin 1B 3UQCRB ubiquinol-cytochrome c reductase binding protein 8UQCRC2 ubiquinol-cytochrome c reductase core protein II 16UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur pol 19UQCRH ubiquinol-cytochrome c reductase hinge protein 1UROS uroporphyrinogen III synthase 10USMG5 up-regulated during skeletal muscle growth 5 homolog ( 10USP10 ubiquitin specific peptidase 10 16USP11 ubiquitin specific peptidase 11 XUSP2 ubiquitin specific peptidase 2 11USP25 ubiquitin specific peptidase 25 21USP5 ubiquitin specific peptidase 5 (isopeptidase T) 12UST uronyl-2-sulfotransferase 6UTRN utrophin 6VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) 17VAMP4 vesicle-associated membrane protein 4 1VAPA VAMP (vesicle-associated membrane protein)-associated 18

VAV3 vav 3 guanine nucleotide exchange factor 1VDAC1 voltage-dependent anion channel 1 5VDAC3 voltage-dependent anion channel 3 8VGF VGF nerve growth factor inducible 7VIPR1 vasoactive intestinal peptide receptor 1 3VLDLR very low density lipoprotein receptor 9VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae) 9VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) 8VPS29 vacuolar protein sorting 29 homolog (S. cerevisiae) 12VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae) 12VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae) 16VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae) 7VRK1 vaccinia related kinase 1 14VSNL1 visinin-like 1 2VTI1B vesicle transport through interaction with t-SNAREs 1B 14WASF1 WAS protein family, member 1 6WASL Wiskott-Aldrich syndrome-like 7WBP11 WW domain binding protein 11 12WBSCR17 Williams-Beuren syndrome chromosome region 17 7WDR12 WD repeat domain 12 2WDR5B WD repeat domain 5B 3WDR7 WD repeat domain 7 18WFDC1 WAP four-disulfide core domain 1 16WFDC2 WAP four-disulfide core domain 2 20WHSC1 Wolf-Hirschhorn syndrome candidate 1 4WNT10A wingless-type MMTV integration site family, member 10A 2WNT10B wingless-type MMTV integration site family, member 10B 12WNT2B wingless-type MMTV integration site family, member 2B 1WNT5B wingless-type MMTV integration site family, member 5B 12WNT6 wingless-type MMTV integration site family, member 6 2WSB2 WD repeat and SOCS box containing 2 12WT1 Wilms tumor 1 11WWP1 WW domain containing E3 ubiquitin protein ligase 1 8XK X-linked Kx blood group XXPO5 exportin 5 6XPO7 exportin 7 8YARS tyrosyl-tRNA synthetase 1YPEL1 yippee-like 1 (Drosophila) 22YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase a 20YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase a 17YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase 7YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase a 22YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase a 8ZDHHC16 zinc finger, DHHC-type containing 16 10ZDHHC18 zinc finger, DHHC-type containing 18 1ZDHHC21 zinc finger, DHHC-type containing 21 9ZDHHC23 zinc finger, DHHC-type containing 23 3ZFP1 ZFP1 zinc finger protein 16

ZFYVE27 zinc finger, FYVE domain containing 27 10ZFYVE28 zinc finger, FYVE domain containing 28 4ZIM2 zinc finger, imprinted 2 19ZMYND19 zinc finger, MYND-type containing 19 9ZNF148 zinc finger protein 148 3ZNF223 zinc finger protein 223 19ZNF233 zinc finger protein 233 19ZNF436 zinc finger protein 436 1ZNF503 zinc finger protein 503 10ZNF540 zinc finger protein 540 19ZNF546 zinc finger protein 546 19ZNF615 zinc finger protein 615 19ZNF91 zinc finger protein 91 19ZNRF1 zinc and ring finger 1, E3 ubiquitin protein ligase 16ZSWIM3 zinc finger, SWIM-type containing 3 20ZWINT ZW10 interacting kinetochore protein 10

Supplementary Table S5A Decreased expression of genes in the caudate of HD with p≤0.001 (Hodges et al. 2006)Gene Start (bp) Gene End (bp)

106075501 1060987108674565 8784575

122920951 122981649183919934 184018015203328219 203447723

7965310 8158832127672935 127680920

63477061 63498380100889994 100896974

41866908 41930542264140 278283

131806990 1320122435527151 5563784

68874143 68979440236686454 236764631

58200080 58235636102479229 102502711

97655963 97664107113889960 113962596

51951667 5199707853970838 54305300

126012381 126388455206443539 206621130

72280969 72568799130404925 130428993

45073853 4522656045574140 4572311624819169 24919839

123282296 1234497583953387 4116185

70607618 7076822574151185 7470930324417879 24442360

3766348 3768526114044056 114046908

67266410 672865563052910 3063107

32168212 3217809677282051 7755996942272153 42323267

151239999 15135855764465499 6447450332329273 3283768152198086 5221432719648136 1967759830053090 30070457

29192774 2992156670592256 70607288

110194186 110440233109616104 109632051

38383704 38631567111766271 111884690110372900 110403730112818109 113383740

60026298 6073349014704804 14871778

151100712 15115788271729000 71809201

101154397 10116159649766968 49807113

924894 101224535578046 35726409

184174689 18418409182659281 82709914

2100988 216446542152946 42171673

115841481 115914081113894748 113905201

31025106 3109645069427530 6967230643311963 43344529

130069837 13014481125880550 26171128

142611044 142614472228082660 228099212

48935723 4895755157571363 57598220

127588345 12759170567619798 67651720

110577042 110713189142770384 143229011

81867721 81871406268727 283010

155946851 156007070130836916 131047263111114559 111305737

63634967 6380927465014113 6502218497764521 9780110913276652 1338726699325898 99388164

218217094 218254356124862130 124877733230978981 231000595

50182778 5024861075918873 75932431

129634604 12964216912737139 1274832397852118 9787254287751512 87841343

3879864 3928079116372668 116410261

41966582 41997497110280756 110351093

3923870 396446489588049 8970930010324023 10708031

153517676 153582939130850595 131016712

46080248 4610433456638175 56646068

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175176258 17518460775038863 75046985

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35540868 3555400143194535 4326691981426393 8204424478959947 7909077338488103 3856557564726911 6474545635731649 3574352116839283 16870414

110644397 11083946917281346 17293875

160272151 16049379493591687 9360174475479037 7551476431812391 3210575573294612 7332528167701886 6773445216946691 1715328015107783 1534867532359906 32382052

3293028 3439913177357837 177372601153004459 153131249192809039 192812283

53851808 53959303163068775 163076802240775514 241357230182641816 182684576

65137431 65227703

22987417 2302019971886703 72403143

103500748 10425609444751808 4481033842743227 43115691

120533480 12057759449689499 49721529

140859807 14121287776142453 76240373

185045364 18510260826132115 26222493

141738204 14174756013726660 1376455875906695 7764996411179761 11348330

7636518 7718607210002565 210022259

84479259 84497790112570380 112898881

40457292 4046858723916545 23923692

101001715 101024032197949987 197956610

66498015 6652453258306247 58324695

4994732 5004063153990759 153992150

20149911 2026710064359148 6437221590847862 9106063615060022 1509431718639910 1867210959595976 5987096645485289 4549706154972187 5511262170003793 7020594542980565 42993690

155320896 155331114128064778 128153914

33193588 33200688165400917 165445355237042205 237833988

33310962 3386610223328823 2343372850445000 5047502478360583 7847907174957219 75021496

124776856 124882668

223596940 22360250351681353 51721031

165989160 16612804735030684 35040448

118161951 118176673165087522 165204067118133377 118152888

51590266 51812864140257286 140385726144330565 144336281

58552924 585828601309909 1329239

17018722 1705417077086716 7721710139031919 3910964612129637 1216996183955777 84492724

4542593 4559808185582496 185633551

70900665 7091853070025247 70043113

167735243 167825568210232799 210246631

95165540 9523254128954901 2900644026169474 2638359770523788 70577670

175477062 175529742222424517 222560948

15254853 1534136817579082 17797129

145936579 14608179170467856 7125257789005771 89178767

150741127 15076347716829400 16880353

215458 23693144941898 44946077

1692800 171255546021690 4606015234229996 34338060

6684713 6713567111087503 111231194230034974 230068999

4490444 458746964988477 6502386514950034 1502299019212646 19722937

4937130 4940251171784370 171999859130339888 130373361

40789412 40810111790475 798333

6436079 6465203128068201 128109245

46652915 4667819398593591 98606379

185143241 1851503821386152 1392724

35943514 3602486844219505 44234151

133988697 13405263639755021 40106089

7812512 78911487919230 7936275

136922264 136925639117907526 118317676233904933 234324516

57563922 57982194140293693 140404433

44275458 4432149427663471 27694976

219627327 21964198071187286 7157208723125295 2318367440097270 4061105347428017 4747216827098815 2716698167237683 67272190

135985424 13604726996998038 9718592020253260 20620561

168661733 169301129145817832 145825842143622790 143635777

85792790 85799488103967201 104029233

57755450 579291682015219 2193624

10961001 11065395151238764 151277896

40624962 40648508168441151 168673445

99027438 9914410010218830 1030741883552880 83709691

66490135 6649781389724099 89838315

122311354 122464219176620084 176630556

11668414 116791591266316 1309328

45687454 4569256949909789 5079411824955034 2500027624954986 2497785026291895 2637432965027408 65040572

185204237 185370185151612065 151699091127472794 127519191127438406 127519355106573663 107164534104641101 105265235

5692667 570138549366584 4952742438244035 3829261472059035 72089032

166733384 16723479638252326 3835724964746283 6487988366685248 6672922640466241 40576464

6633343 667438641833079 4190730811054584 1106002435832966 35921342

126262919 12626914442581840 4259511418418864 1843456238207999 3821306773165012 7317663384643707 84690803

116953238 11723010338143649 38151265

111496033 111512590191029576 191151596

73420369 7374770890167590 90238137

3854527 40932101177558 1228435

43582758 4362678698445185 98577940

241492674 241509730

132207492 13233184779610814 7966617563639705 6365342773978923 73994622

123109500 12326857636843640 3696647246719507 46746994

7219456 735481073699206 73719672

127611760 12769293624809656 2505029747936487 4800132652652709 5270090943824509 43862503

112040785 112175408149903318 149917882

91099950 9130130947571898 4761985312004402 1219140033420070 3345754139349925 39385588

1989660 199427532628759 32728048

150601080 15065922063228315 6361692149187804 4920025978863993 7945200867006778 6705086345240301 4528631950621307 5066839443267878 4327765055171199 55180441

114089291 11415391961515313 6158114838006582 3812881997731908 97740472

121989174 12225454526225936 2639168562771303 6278734269364743 6937001369350984 6937001379932343 8003584813266542 1332858382752064 82945922

124622836 12463539864049836 6407234773939169 73972287

159778498 159789749

179591613 179691272103928462 104052667151770107 151791416

41367333 4139932669355561 6940857175647786 75761872

2163929 2171877175917873 176034680

24117160 24495282119417378 119424985

31118416 31559977154832697 155257723201955491 201970661

48893447 4889814345972449 4600373439480412 3949378558408494 5842761481583683 8168930579571773 79726882

170990823 17123131496364606 9651391862390526 62844631

100473113 100577636191949043 192195709118531041 118547280

51751561 5181636884905625 8490667512063377 1214420745823214 45833745

1274371 130965454899387 5496195638681948 3868542144942130 44960486

100363431 10040139843403061 4351072882363206 8237082869048897 6909060480034745 80231232

125119049 1252644076867119 6870948

154155304 15419464816067021 1610300518128311 18155074

211326615 2113749463651639 37175977680843 7687703

39147811 3917053242224931 42452051

72087266 72670757228393673 228406840

6448613 647445958982638 59106921

155173787 15518497155262182 5527111950975262 5109606114143702 14532128

114938193 1149776762047465 20887203188925 3377882

43243680 4328825937073226 37203112

2631951 266480230720201 3072542615417215 15766649

139526431 13962843323203020 23591793

4269259 436662858555712 5855896093405673 9344226248008400 4806470829764371 2985068456563639 5656786841256413 4126845575549480 7560602063840940 63891562

131894651 13192316717601328 17688365

176810477 17688089535235457 35796550

119173517 11920515396225920 9623563421952660 2198366029205321 2921354146303631 46316776

125784980 125823248103389041 103396466

84699978 8477992247232690 47248328

119355215 11938172615730025 15880069

6852128 6866632148747328 149076990144285701 144853034

8159149 8163546171700160 171742247

9914002 9960021

107571160 107965144133971915 134005133

42391624 42405897101162509 101165593

42489299 425375732621834 2660053

77177353 77421541144423601 144428563110491097 110502117122229564 122266521

46656132 4668951838722963 3893239496797304 9693172217539126 1765701867647075 67674831

110099819 110180004123681935 123749067

14784579 1480354071132169 71713600

202874782 203014798122412332 122416051

56651343 5703660684294646 8432985145469706 45481532

1871424 1982207218880363 218899581

48965340 48971763112466541 112530165

1529891 1647243218859821 218874233118032694 118062430

32387775 3243563086342738 8647842037685759 3773213043522330 4357607521919671 2200658532775237 3281815321697544 2173583444885676 44908532

1344272 140037876326794 7635903131944461 31957603

100916525 10095338897446131 9745737026826710 2685760214611071 14693471

113947901 11396540175148492 75172236

97737121 977609072269582 2418663

56774552 56840729137582079 137590490125225561 125375354

44051367 4406799144259880 4427531723359448 2336944275397830 7540190637551406 3761409739984134 4002104151991332 5200823023304991 2339556074999030 7511099445857617 4587912256357228 56361275

Supplementary Table S5B: Increased expression of genes in the caudate of HD with p≤0.001 (Hodges et al. 2006)Associated Gen Description

alpha-2-macroglobulin [Source:HGNC Symbol;Acc:HGNC:7]aminoadipate-semialdehyde synthase [Source:HGNC Symbol;Acc:HGNC:ATP-binding cassette, sub-family A (ABC1), member 1 [Source:HGNC SyATP-binding cassette, sub-family A (ABC1), member 2 [Source:HGNC SyATP-binding cassette, sub-family C (CFTR/MRP), member 1 [Source:HGATP-binding cassette, sub-family C (CFTR/MRP), member 10 [Source:HATP-binding cassette, sub-family C (CFTR/MRP), member 3 [Source:HGATP-binding cassette, sub-family C (CFTR/MRP), member 4 [Source:HGATP-binding cassette, sub-family C (CFTR/MRP), member 9 [Source:HGATP-binding cassette, sub-family D (ALD), member 3 [Source:HGNC SymATP-binding cassette, sub-family D (ALD), member 4 [Source:HGNC Symabhydrolase domain containing 3 [Source:HGNC Symbol;Acc:HGNC:1871abhydrolase domain containing 4 [Source:HGNC Symbol;Acc:HGNC:2015abhydrolase domain containing 5 [Source:HGNC Symbol;Acc:HGNC:2139abl-interactor 1 [Source:HGNC Symbol;Acc:HGNC:11320]ABL proto-oncogene 1, non-receptor tyrosine kinase [Source:HGNC Symactin binding LIM protein 1 [Source:HGNC Symbol;Acc:HGNC:78]acetyl-CoA acyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:82]acetyl-CoA acyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:83]acyl-CoA dehydrogenase, very long chain [Source:HGNC Symbol;Acc:HGNacyl-CoA binding domain containing 5 [Source:HGNC Symbol;Acc:HGNC:acyl-CoA oxidase 1, palmitoyl [Source:HGNC Symbol;Acc:HGNC:119]acyl-CoA oxidase 2, branched chain [Source:HGNC Symbol;Acc:HGNC:120acid phosphatase 6, lysophosphatidic [Source:HGNC Symbol;Acc:HGNC:2acyl-CoA synthetase long-chain family member 3 [Source:HGNC Symbolactinin, alpha 4 [Source:HGNC Symbol;Acc:HGNC:166]activin A receptor, type IIB [Source:HGNC Symbol;Acc:HGNC:174]ADAM metallopeptidase domain 17 [Source:HGNC Symbol;Acc:HGNC:19ADAM metallopeptidase domain 33 [Source:HGNC Symbol;Acc:HGNC:15ADAM metallopeptidase with thrombospondin type 1 motif, 9 [Sourceadenosine deaminase, RNA-specific, B2 (non-functional) [Source:HGNCadenylate cyclase 2 (brain) [Source:HGNC Symbol;Acc:HGNC:233]adenylate cyclase 6 [Source:HGNC Symbol;Acc:HGNC:237]adenylate cyclase 7 [Source:HGNC Symbol;Acc:HGNC:238]adenylate cyclase 8 (brain) [Source:HGNC Symbol;Acc:HGNC:239]adenylate cyclase activating polypeptide 1 (pituitary) receptor type I adducin 1 (alpha) [Source:HGNC Symbol;Acc:HGNC:243]adducin 3 (gamma) [Source:HGNC Symbol;Acc:HGNC:245]alcohol dehydrogenase 1B (class I), beta polypeptide [Source:HGNC Syalcohol dehydrogenase, iron containing, 1 [Source:HGNC Symbol;Acc:Hactivity-dependent neuroprotector homeobox [Source:HGNC Symbol;Acadenosine A3 receptor [Source:HGNC Symbol;Acc:HGNC:268]ADP-ribosylarginine hydrolase [Source:HGNC Symbol;Acc:HGNC:269]ADP-ribosylhydrolase like 2 [Source:HGNC Symbol;Acc:HGNC:21304]AE binding protein 1 [Source:HGNC Symbol;Acc:HGNC:303]argonaute RISC catalytic component 3 [Source:HGNC Symbol;Acc:HGNC:

A2MAASSABCA1ABCA2ABCC1ABCC10ABCC3ABCC4ABCC9ABCD3ABCD4ABHD3ABHD4ABHD5ABI1ABL1ABLIM1ACAA1ACAA2ACADVLACBD5ACOX1ACOX2ACP6ACSL3ACTN4ACVR2BADAM17ADAM33ADAMTS9ADARB2ADCY2ADCY6ADCY7ADCY8ADCYAP1R1ADD1ADD3ADH1BADHFE1ADNPADORA3ADPRHADPRHL2AEBP1AGO3

http://asia.ensembl.org/Homo_sapiens/Gene/Summary?db=core;g=ENSG00000175899














































1-acylglycerol-3-phosphate O-acyltransferase 3 [Source:HGNC Symbol;Aangiotensinogen (serpin peptidase inhibitor, clade A, member 8) [Souangiotensin II receptor-associated protein [Source:HGNC Symbol;Acc:Hadenosylhomocysteinase-like 1 [Source:HGNC Symbol;Acc:HGNC:344]AHNAK nucleoprotein [Source:HGNC Symbol;Acc:HGNC:347]AHA1, activator of heat shock 90kDa protein ATPase homolog 2 (yeastadenylate kinase 1 [Source:HGNC Symbol;Acc:HGNC:361]adenylate kinase 2 [Source:HGNC Symbol;Acc:HGNC:362]adenylate kinase 3 [Source:HGNC Symbol;Acc:HGNC:17376]A kinase (PRKA) anchor protein 10 [Source:HGNC Symbol;Acc:HGNC:368]A kinase (PRKA) anchor protein 13 [Source:HGNC Symbol;Acc:HGNC:371]A kinase (PRKA) anchor protein 2 [Source:HGNC Symbol;Acc:HGNC:372]AT-hook transcription factor [Source:HGNC Symbol;Acc:HGNC:24108]aldo-keto reductase family 1, member C1 [Source:HGNC Symbol;Acc:HGaldo-keto reductase family 1, member C2 [Source:HGNC Symbol;Acc:HGaldo-keto reductase family 1, member C3 [Source:HGNC Symbol;Acc:HGaldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductasaldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductasv-akt murine thymoma viral oncogene homolog 2 [Source:HGNC Symbolaminolevulinate dehydratase [Source:HGNC Symbol;Acc:HGNC:395]aldehyde dehydrogenase 4 family, member A1 [Source:HGNC Symbol;Acaldehyde dehydrogenase 6 family, member A1 [Source:HGNC Symbol;Aaldehyde dehydrogenase 7 family, member A1 [Source:HGNC Symbol;Acaldehyde dehydrogenase 9 family, member A1 [Source:HGNC Symbol;AcAlstrom syndrome 1 [Source:HGNC Symbol;Acc:HGNC:428]arachidonate 5-lipoxygenase [Source:HGNC Symbol;Acc:HGNC:435]ALX homeobox 3 [Source:HGNC Symbol;Acc:HGNC:449]

AMOT angiomotin [Source:HGNC Symbol;Acc:HGNC:17810]angiomotin like 1 [Source:HGNC Symbol;Acc:HGNC:17811]angiomotin like 2 [Source:HGNC Symbol;Acc:HGNC:17812]anaphase promoting complex subunit 2 [Source:HGNC Symbol;Acc:HGNCanaphase promoting complex subunit 4 [Source:HGNC Symbol;Acc:HGNCanaphase promoting complex subunit 5 [Source:HGNC Symbol;Acc:HGNCangiogenin, ribonuclease, RNase A family, 5 [Source:HGNC Symbol;Acc:angiopoietin 1 [Source:HGNC Symbol;Acc:HGNC:484]ankyrin repeat and FYVE domain containing 1 [Source:HGNC Symbol;Acankyrin repeat and IBR domain containing 1 [Source:HGNC Symbol;Acc:ankyrin repeat domain 10 [Source:HGNC Symbol;Acc:HGNC:20265]ankyrin repeat domain 28 [Source:HGNC Symbol;Acc:HGNC:29024]ankyrin repeat domain 9 [Source:HGNC Symbol;Acc:HGNC:20096]anillin, actin binding protein [Source:HGNC Symbol;Acc:HGNC:14082]acidic (leucine-rich) nuclear phosphoprotein 32 family, member B [Soanthrax toxin receptor 1 [Source:HGNC Symbol;Acc:HGNC:21014]anthrax toxin receptor 2 [Source:HGNC Symbol;Acc:HGNC:21732]annexin A1 [Source:HGNC Symbol;Acc:HGNC:533]annexin A2 [Source:HGNC Symbol;Acc:HGNC:537]annexin A3 [Source:HGNC Symbol;Acc:HGNC:541]annexin A4 [Source:HGNC Symbol;Acc:HGNC:542]

AGPAT3AGTAGTRAPAHCYL1AHNAKAHSA2AK1AK2AK3AKAP10AKAP13AKAP2AKNAAKR1C1AKR1C2AKR1C3AKR7A2AKR7A3AKT2ALADALDH4A1ALDH6A1ALDH7A1ALDH9A1ALMS1ALOX5ALX3

AMOTL1AMOTL2ANAPC2ANAPC4ANAPC5ANGANGPT1ANKFY1ANKIB1ANKRD10ANKRD28ANKRD9ANLNANP32BANTXR1ANTXR2ANXA1ANXA2ANXA3ANXA4
















































annexin A5 [Source:HGNC Symbol;Acc:HGNC:543]AP1S2 adaptor-related protein complex 1, sigma 2 subunit [Source:HGNC Symb

adaptor-related protein complex 4, epsilon 1 subunit [Source:HGNC Syapoptotic peptidase activating factor 1 [Source:HGNC Symbol;Acc:HGNCamyloid beta (A4) precursor protein-binding, family A, member 3 [Souadenomatosis polyposis coli down-regulated 1 [Source:HGNC Symbol;A

APLN apelin [Source:HGNC Symbol;Acc:HGNC:16665]apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 [apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G apolipoprotein D [Source:HGNC Symbol;Acc:HGNC:612]aquaporin 1 (Colton blood group) [Source:HGNC Symbol;Acc:HGNC:633]aquaporin 4 [Source:HGNC Symbol;Acc:HGNC:637]ADP-ribosylation factor GTPase activating protein 1 [Source:HGNC SymADP-ribosylation factor GTPase activating protein 3 [Source:HGNC SymbRho GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:673]Rho GTPase activating protein 12 [Source:HGNC Symbol;Acc:HGNC:1634Rho GTPase activating protein 18 [Source:HGNC Symbol;Acc:HGNC:2103Rho GTPase activating protein 21 [Source:HGNC Symbol;Acc:HGNC:2372Rho GTPase activating protein 23 [Source:HGNC Symbol;Acc:HGNC:2929Rho GTPase activating protein 5 [Source:HGNC Symbol;Acc:HGNC:675]

ARHGAP6 Rho GTPase activating protein 6 [Source:HGNC Symbol;Acc:HGNC:676]Rho GDP dissociation inhibitor (GDI) beta [Source:HGNC Symbol;Acc:HGRho guanine nucleotide exchange factor (GEF) 10 [Source:HGNC Symbol

ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 [Source:HGNC SAT rich interactive domain 1B (SWI1-like) [Source:HGNC Symbol;Acc:HGAT rich interactive domain 2 (ARID, RFX-like) [Source:HGNC Symbol;Accariadne RBR E3 ubiquitin protein ligase 2 [Source:HGNC Symbol;Acc:HGNaryl hydrocarbon receptor nuclear translocator [Source:HGNC Symbol;Aactin related protein 2/3 complex, subunit 1B, 41kDa [Source:HGNC Syarrestin, beta 1 [Source:HGNC Symbol;Acc:HGNC:711]arrestin domain containing 2 [Source:HGNC Symbol;Acc:HGNC:25225]arrestin domain containing 3 [Source:HGNC Symbol;Acc:HGNC:29263]arrestin domain containing 4 [Source:HGNC Symbol;Acc:HGNC:28087]

ARSD arylsulfatase D [Source:HGNC Symbol;Acc:HGNC:717]achaete-scute family bHLH transcription factor 1 [Source:HGNC Symbolaspartate beta-hydroxylase [Source:HGNC Symbol;Acc:HGNC:757]astrotactin 2 [Source:HGNC Symbol;Acc:HGNC:17021]additional sex combs like transcriptional regulator 1 [Source:HGNC Syactivating transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:783]activating transcription factor 4 [Source:HGNC Symbol;Acc:HGNC:786]activating transcription factor 7 interacting protein [Source:HGNC SymATM serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:795]atonal homolog 8 (Drosophila) [Source:HGNC Symbol;Acc:HGNC:24126]ATPase, class V, type 10A [Source:HGNC Symbol;Acc:HGNC:13542]ATPase, class VI, type 11B [Source:HGNC Symbol;Acc:HGNC:13553]ATPase, Na+/K+ transporting, alpha 2 polypeptide [Source:HGNC SymboATPase, Ca++ transporting, plasma membrane 4 [Source:HGNC Symbol;ATPase, aminophospholipid transporter, class I, type 8B, member 1 [S

ANXA5

AP4E1APAF1APBA3APCDD1

APOBEC2APOBEC3GAPODAQP1AQP4ARFGAP1ARFGAP3ARHGAP1ARHGAP12ARHGAP18ARHGAP21ARHGAP23ARHGAP5

ARHGDIBARHGEF10

ARID1BARID2ARIH2ARNTARPC1BARRB1ARRDC2ARRDC3ARRDC4

ASCL1ASPHASTN2ASXL1ATF1ATF4ATF7IPATMATOH8ATP10AATP11BATP1A2ATP2B4ATP8B1












































ancient ubiquitous protein 1 [Source:HGNC Symbol;Acc:HGNC:891]autism susceptibility candidate 2 [Source:HGNC Symbol;Acc:HGNC:14262AXL receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:905]alpha-2-glycoprotein 1, zinc-binding [Source:HGNC Symbol;Acc:HGNC:91beta-1,3-glucuronyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:922]UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 [SouBTB and CNC homology 1, basic leucine zipper transcription factor 1 [BAI1-associated protein 3 [Source:HGNC Symbol;Acc:HGNC:948]barrier to autointegration factor 1 [Source:HGNC Symbol;Acc:HGNC:173BTG3 associated nuclear protein [Source:HGNC Symbol;Acc:HGNC:13450BRCA1 associated RING domain 1 [Source:HGNC Symbol;Acc:HGNC:952]bromodomain adjacent to zinc finger domain, 1A [Source:HGNC Symbolbromodomain adjacent to zinc finger domain, 1B [Source:HGNC Symbolbromodomain adjacent to zinc finger domain, 2A [Source:HGNC Symbolbromodomain adjacent to zinc finger domain, 2B [Source:HGNC Symbolbutyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetBardet-Biedl syndrome 4 [Source:HGNC Symbol;Acc:HGNC:969]bobby sox homolog (Drosophila) [Source:HGNC Symbol;Acc:HGNC:14422brevican [Source:HGNC Symbol;Acc:HGNC:23059]breast cancer anti-estrogen resistance 3 [Source:HGNC Symbol;Acc:HGNbreast carcinoma amplified sequence 1 [Source:HGNC Symbol;Acc:HGNCBRCA2 and CDKN1A interacting protein [Source:HGNC Symbol;Acc:HGNCB-cell CLL/lymphoma 10 [Source:HGNC Symbol;Acc:HGNC:989]B-cell CLL/lymphoma 2 [Source:HGNC Symbol;Acc:HGNC:990]BCL2-like 1 [Source:HGNC Symbol;Acc:HGNC:992]BCL2-like 11 (apoptosis facilitator) [Source:HGNC Symbol;Acc:HGNC:994]B-cell CLL/lymphoma 3 [Source:HGNC Symbol;Acc:HGNC:998]B-cell CLL/lymphoma 6 [Source:HGNC Symbol;Acc:HGNC:1001]B-cell CLL/lymphoma 9 [Source:HGNC Symbol;Acc:HGNC:1008]

BCOR BCL6 corepressor [Source:HGNC Symbol;Acc:HGNC:20893]bone gamma-carboxyglutamate (gla) protein [Source:HGNC Symbol;Acc

BGN biglycan [Source:HGNC Symbol;Acc:HGNC:1044]betaine--homocysteine S-methyltransferase 2 [Source:HGNC Symbol;Acbicaudal D homolog 1 (Drosophila) [Source:HGNC Symbol;Acc:HGNC:104bicaudal D homolog 2 (Drosophila) [Source:HGNC Symbol;Acc:HGNC:172bridging integrator 1 [Source:HGNC Symbol;Acc:HGNC:1052]bridging integrator 3 [Source:HGNC Symbol;Acc:HGNC:1054]baculoviral IAP repeat containing 2 [Source:HGNC Symbol;Acc:HGNC:590biliverdin reductase A [Source:HGNC Symbol;Acc:HGNC:1062]BMP2 inducible kinase [Source:HGNC Symbol;Acc:HGNC:18041]bone morphogenetic protein 7 [Source:HGNC Symbol;Acc:HGNC:1074]bone morphogenetic protein receptor, type IA [Source:HGNC Symbol;ABCL2/adenovirus E1B 19kDa interacting protein 2 [Source:HGNC SymbolBOC cell adhesion associated, oncogene regulated [Source:HGNC SymboBCL2-related ovarian killer [Source:HGNC Symbol;Acc:HGNC:1087]BRCA1 associated protein [Source:HGNC Symbol;Acc:HGNC:1099]bromodomain containing 1 [Source:HGNC Symbol;Acc:HGNC:1102]bromodomain containing 2 [Source:HGNC Symbol;Acc:HGNC:1103]

AUP1AUTS2AXLAZGP1B3GAT2B3GNT5BACH1BAIAP3BANF1BANPBARD1BAZ1ABAZ1BBAZ2ABAZ2BBBOX1BBS4BBXBCANBCAR3BCAS1BCCIPBCL10BCL2BCL2L1BCL2L11BCL3BCL6BCL9

BGLAP

BHMT2BICD1BICD2BIN1BIN3BIRC2BLVRABMP2KBMP7BMPR1ABNIP2BOCBOKBRAPBRD1BRD2















































bromodomain containing 3 [Source:HGNC Symbol;Acc:HGNC:1104]bromodomain containing 4 [Source:HGNC Symbol;Acc:HGNC:13575]bromodomain containing 7 [Source:HGNC Symbol;Acc:HGNC:14310]bromodomain containing 8 [Source:HGNC Symbol;Acc:HGNC:19874]breast cancer metastasis suppressor 1 [Source:HGNC Symbol;Acc:HGNC:bone marrow stromal cell antigen 2 [Source:HGNC Symbol;Acc:HGNC:11BTB (POZ) domain containing 7 [Source:HGNC Symbol;Acc:HGNC:18269]biotinidase [Source:HGNC Symbol;Acc:HGNC:1122]B-cell translocation gene 1, anti-proliferative [Source:HGNC Symbol;AcBTG family, member 2 [Source:HGNC Symbol;Acc:HGNC:1131]butyrophilin, subfamily 3, member A2 [Source:HGNC Symbol;Acc:HGNC:butyrophilin, subfamily 3, member A3 [Source:HGNC Symbol;Acc:HGNC:butyrophilin-like 9 [Source:HGNC Symbol;Acc:HGNC:24176]BUB3 mitotic checkpoint protein [Source:HGNC Symbol;Acc:HGNC:1151]chromosome 10 open reading frame 11 [Source:HGNC Symbol;Acc:HGNCchromosome 14 open reading frame 79 [Source:HGNC Symbol;Acc:HGNCchromosome 19 open reading frame 18 [Source:HGNC Symbol;Acc:HGNCchromosome 19 open reading frame 25 [Source:HGNC Symbol;Acc:HGNCchromosome 19 open reading frame 33 [Source:HGNC Symbol;Acc:HGNCchromosome 1 open reading frame 27 [Source:HGNC Symbol;Acc:HGNC:complement component 1, q subcomponent, A chain [Source:HGNC SymC1q and tumor necrosis factor related protein 1 [Source:HGNC Symbol;C1q and tumor necrosis factor related protein 5 [Source:HGNC Symbol;complement component 1, r subcomponent [Source:HGNC Symbol;Acc:complement component 1, s subcomponent [Source:HGNC Symbol;Acc:chromosome 20 open reading frame 144 [Source:HGNC Symbol;Acc:HGNchromosome 20 open reading frame 194 [Source:HGNC Symbol;Acc:HGNchromosome 21 open reading frame 91 [Source:HGNC Symbol;Acc:HGNCcomplement component 3 [Source:HGNC Symbol;Acc:HGNC:1318]complement component 4A (Rodgers blood group) [Source:HGNC Symbocomplement component 4B (Chido blood group) [Source:HGNC Symbol;chromosome 6 open reading frame 89 [Source:HGNC Symbol;Acc:HGNC:chromosome 8 open reading frame 4 [Source:HGNC Symbol;Acc:HGNC:1chromosome 9 open reading frame 114 [Source:HGNC Symbol;Acc:HGNCchromosome 9 open reading frame 64 [Source:HGNC Symbol;Acc:HGNC:chromosome 9 open reading frame 89 [Source:HGNC Symbol;Acc:HGNC:carbonic anhydrase VIII [Source:HGNC Symbol;Acc:HGNC:1382]calcium binding protein 39-like [Source:HGNC Symbol;Acc:HGNC:20290]caldesmon 1 [Source:HGNC Symbol;Acc:HGNC:1441]calcium/calmodulin-dependent protein kinase II delta [Source:HGNC Scalcium/calmodulin-dependent protein kinase II gamma [Source:HGNC capping protein (actin filament), gelsolin-like [Source:HGNC Symbol;Accalpain 1, (mu/I) large subunit [Source:HGNC Symbol;Acc:HGNC:1476]calpain 2, (m/II) large subunit [Source:HGNC Symbol;Acc:HGNC:1479]calpain, small subunit 2 [Source:HGNC Symbol;Acc:HGNC:16371]calcyphosine [Source:HGNC Symbol;Acc:HGNC:1487]calcyphosine 2 [Source:HGNC Symbol;Acc:HGNC:16471]capping protein (actin filament) muscle Z-line, alpha 1 [Source:HGNC S

BRD3BRD4BRD7BRD8BRMS1BST2BTBD7BTDBTG1BTG2BTN3A2BTN3A3BTNL9BUB3C10orf11C14orf79C19orf18C19orf25C19orf33C1orf27C1QAC1QTNF1C1QTNF5C1RC1SC20orf144C20orf194C21orf91C3C4AC4BC6orf89C8orf4C9orf114C9orf64C9orf89CA8CAB39LCALD1CAMK2DCAMK2GCAPGCAPN1CAPN2CAPNS2CAPSCAPS2CAPZA1

















































capping protein (actin filament) muscle Z-line, alpha 2 [Source:HGNC Scaspase recruitment domain family, member 6 [Source:HGNC Symbol;A

CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) CASK interacting protein 2 [Source:HGNC Symbol;Acc:HGNC:18200]caspase 1, apoptosis-related cysteine peptidase [Source:HGNC Symbol;caspase 2, apoptosis-related cysteine peptidase [Source:HGNC Symbol;caspase 3, apoptosis-related cysteine peptidase [Source:HGNC Symbol;caspase 6, apoptosis-related cysteine peptidase [Source:HGNC Symbol;caspase 7, apoptosis-related cysteine peptidase [Source:HGNC Symbol;calpastatin [Source:HGNC Symbol;Acc:HGNC:1515]catalase [Source:HGNC Symbol;Acc:HGNC:1516]caveolin 1, caveolae protein, 22kDa [Source:HGNC Symbol;Acc:HGNC:15caveolin 2 [Source:HGNC Symbol;Acc:HGNC:1528]core-binding factor, runt domain, alpha subunit 2; translocated to, 2 core-binding factor, beta subunit [Source:HGNC Symbol;Acc:HGNC:1539]Cbl proto-oncogene, E3 ubiquitin protein ligase [Source:HGNC Symbol;Cbl proto-oncogene B, E3 ubiquitin protein ligase [Source:HGNC Symbocystathionine-beta-synthase [Source:HGNC Symbol;Acc:HGNC:1550]cystathionine-beta-synthase [Source:HGNC Symbol;Acc:HGNC:1550]cell division cycle and apoptosis regulator 1 [Source:HGNC Symbol;Acccoiled-coil domain containing 8 [Source:HGNC Symbol;Acc:HGNC:25367]chemokine (C-C motif) ligand 5 [Source:HGNC Symbol;Acc:HGNC:10632]cyclin K [Source:HGNC Symbol;Acc:HGNC:1596]cyclin L2 [Source:HGNC Symbol;Acc:HGNC:20570]cyclin T1 [Source:HGNC Symbol;Acc:HGNC:1599]copper chaperone for superoxide dismutase [Source:HGNC Symbol;AccCD109 molecule [Source:HGNC Symbol;Acc:HGNC:21685]CD151 molecule (Raph blood group) [Source:HGNC Symbol;Acc:HGNC:16CD163 molecule [Source:HGNC Symbol;Acc:HGNC:1631]CD164 molecule, sialomucin [Source:HGNC Symbol;Acc:HGNC:1632]CD22 molecule [Source:HGNC Symbol;Acc:HGNC:1643]CD24 molecule [Source:HGNC Symbol;Acc:HGNC:1645]CD2-associated protein [Source:HGNC Symbol;Acc:HGNC:14258]CD44 molecule (Indian blood group) [Source:HGNC Symbol;Acc:HGNC:16CD63 molecule [Source:HGNC Symbol;Acc:HGNC:1692]CD68 molecule [Source:HGNC Symbol;Acc:HGNC:1693]CD81 molecule [Source:HGNC Symbol;Acc:HGNC:1701]CD86 molecule [Source:HGNC Symbol;Acc:HGNC:1705]

CD99 CD99 molecule [Source:HGNC Symbol;Acc:HGNC:7082]cell division cycle 14A [Source:HGNC Symbol;Acc:HGNC:1718]cell division cycle 16 [Source:HGNC Symbol;Acc:HGNC:1720]cell division cycle 26 [Source:HGNC Symbol;Acc:HGNC:17839]CDC42 binding protein kinase alpha (DMPK-like) [Source:HGNC Symbol;CDC42 effector protein (Rho GTPase binding) 4 [Source:HGNC Symbol;ACDC42 effector protein (Rho GTPase binding) 5 [Source:HGNC Symbol;Acell division cycle associated 7 [Source:HGNC Symbol;Acc:HGNC:14628]cadherin 19, type 2 [Source:HGNC Symbol;Acc:HGNC:1758]cadherin 2, type 1, N-cadherin (neuronal) [Source:HGNC Symbol;Acc:HG

CAPZA2CARD6

CASKIN2CASP1CASP2CASP3CASP6CASP7CASTCATCAV1CAV2CBFA2T2CBFBCBLCBLBCBSCBSCCAR1CCDC8CCL5CCNKCCNL2CCNT1CCSCD109CD151CD163CD164CD22CD24CD2APCD44CD63CD68CD81CD86

CDC14ACDC16CDC26CDC42BPACDC42EP4CDC42EP5CDCA7CDH19CDH2















































cadherin-related 23 [Source:HGNC Symbol;Acc:HGNC:13733]cyclin-dependent kinase 2 associated protein 1 [Source:HGNC Symbol;cyclin-dependent kinase 3 [Source:HGNC Symbol;Acc:HGNC:1772]cyclin-dependent kinase 4 [Source:HGNC Symbol;Acc:HGNC:1773]CDK5 regulatory subunit associated protein 2 [Source:HGNC Symbol;Accyclin-dependent kinase inhibitor 1C (p57, Kip2) [Source:HGNC Symbol;cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) [Source:HGNCDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 [Scat eye syndrome chromosome region, candidate 1 [Source:HGNC Symbcentromere protein B, 80kDa [Source:HGNC Symbol;Acc:HGNC:1852]centrin, EF-hand protein, 3 [Source:HGNC Symbol;Acc:HGNC:1868]craniofacial development protein 1 [Source:HGNC Symbol;Acc:HGNC:187CASP8 and FADD-like apoptosis regulator [Source:HGNC Symbol;Acc:HGcoiled-coil-helix-coiled-coil-helix domain containing 5 [Source:HGNC Schromodomain helicase DNA binding protein 1 [Source:HGNC Symbol;Achromodomain helicase DNA binding protein 1-like [Source:HGNC Symbchromodomain helicase DNA binding protein 2 [Source:HGNC Symbol;Acholine dehydrogenase [Source:HGNC Symbol;Acc:HGNC:24288]calcium homeostasis endoplasmic reticulum protein [Source:HGNC Symchitinase 3-like 1 (cartilage glycoprotein-39) [Source:HGNC Symbol;Acccysteine-rich hydrophobic domain 2 [Source:HGNC Symbol;Acc:HGNC:19choline phosphotransferase 1 [Source:HGNC Symbol;Acc:HGNC:17852]chromatin accessibility complex 1 [Source:HGNC Symbol;Acc:HGNC:1354carbohydrate (chondroitin 6) sulfotransferase 3 [Source:HGNC Symbol;carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 6 [Source:Hchondroitin sulfate synthase 1 [Source:HGNC Symbol;Acc:HGNC:17198]churchill domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20099]calcium and integrin binding 1 (calmyrin) [Source:HGNC Symbol;Acc:HGcyclin-dependent kinase 2 interacting protein [Source:HGNC Symbol;Accold inducible RNA binding protein [Source:HGNC Symbol;Acc:HGNC:198cytoskeleton-associated protein 4 [Source:HGNC Symbol;Acc:HGNC:1699chemokine-like factor [Source:HGNC Symbol;Acc:HGNC:13253]CDC28 protein kinase regulatory subunit 1B [Source:HGNC Symbol;Acc:chloride channel, voltage-sensitive 7 [Source:HGNC Symbol;Acc:HGNC:2claudin 5 [Source:HGNC Symbol;Acc:HGNC:2047]chloride intracellular channel 1 [Source:HGNC Symbol;Acc:HGNC:2062]chloride intracellular channel 4 [Source:HGNC Symbol;Acc:HGNC:13518]chloride intracellular channel 6 [Source:HGNC Symbol;Acc:HGNC:2065]CDC-like kinase 1 [Source:HGNC Symbol;Acc:HGNC:2068]CDC-like kinase 2 [Source:HGNC Symbol;Acc:HGNC:2069]calmin (calponin-like, transmembrane) [Source:HGNC Symbol;Acc:HGNCceroid-lipofuscinosis, neuronal 5 [Source:HGNC Symbol;Acc:HGNC:2076]ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental rchloride channel, nucleotide-sensitive, 1A [Source:HGNC Symbol;Acc:Hclusterin [Source:HGNC Symbol;Acc:HGNC:2095]cytidine monophosphate N-acetylneuraminic acid synthetase [Source:cyclin and CBS domain divalent metal cation transport mediator 3 [SoCCR4-NOT transcription complex, subunit 2 [Source:HGNC Symbol;Acc:

CDH23CDK2AP1CDK3CDK4CDK5RAP2CDKN1CCDKN2CCDS2CECR1CENPBCETN3CFDP1CFLARCHCHD5CHD1CHD1LCHD2CHDHCHERPCHI3L1CHIC2CHPT1CHRAC1CHST3CHST6CHSY1CHURC1CIB1CINPCIRBPCKAP4CKLFCKS1BCLCN7CLDN5CLIC1CLIC4CLIC6CLK1CLK2CLMNCLN5CLN8CLNS1ACLUCMASCNNM3CNOT2

















































CCR4-NOT transcription complex, subunit 6-like [Source:HGNC Symbol;CCR4-NOT transcription complex, subunit 8 [Source:HGNC Symbol;Acc:contactin 2 (axonal) [Source:HGNC Symbol;Acc:HGNC:2172]cordon-bleu WH2 repeat protein [Source:HGNC Symbol;Acc:HGNC:22199component of oligomeric golgi complex 2 [Source:HGNC Symbol;Acc:HGcomponent of oligomeric golgi complex 4 [Source:HGNC Symbol;Acc:HGcollagen, type XVIII, alpha 1 [Source:HGNC Symbol;Acc:HGNC:2195]collagen, type I, alpha 2 [Source:HGNC Symbol;Acc:HGNC:2198]collagen, type XXI, alpha 1 [Source:HGNC Symbol;Acc:HGNC:17025]collagen, type XXVII, alpha 1 [Source:HGNC Symbol;Acc:HGNC:22986]collagen, type IV, alpha 3 (Goodpasture antigen) [Source:HGNC Symbol

COL4A5 collagen, type IV, alpha 5 [Source:HGNC Symbol;Acc:HGNC:2207]COL4A6 collagen, type IV, alpha 6 [Source:HGNC Symbol;Acc:HGNC:2208]

collagen, type V, alpha 1 [Source:HGNC Symbol;Acc:HGNC:2209]collagen, type VI, alpha 1 [Source:HGNC Symbol;Acc:HGNC:2211]collagen, type VI, alpha 2 [Source:HGNC Symbol;Acc:HGNC:2212]collagen, type VI, alpha 3 [Source:HGNC Symbol;Acc:HGNC:2213]collagen, type VIII, alpha 1 [Source:HGNC Symbol;Acc:HGNC:2215]collagen, type IX, alpha 2 [Source:HGNC Symbol;Acc:HGNC:2218]collectin sub-family member 12 [Source:HGNC Symbol;Acc:HGNC:16016]COMM domain containing 10 [Source:HGNC Symbol;Acc:HGNC:30201]COMM domain containing 5 [Source:HGNC Symbol;Acc:HGNC:17902]catechol-O-methyltransferase [Source:HGNC Symbol;Acc:HGNC:2228]coronin, actin binding protein, 1B [Source:HGNC Symbol;Acc:HGNC:2253coronin, actin binding protein, 1C [Source:HGNC Symbol;Acc:HGNC:2254coactosin-like F-actin binding protein 1 [Source:HGNC Symbol;Acc:HGNCcytochrome c oxidase assembly homolog 15 (yeast) [Source:HGNC Symbceruloplasmin (ferroxidase) [Source:HGNC Symbol;Acc:HGNC:2295]cytoplasmic polyadenylation element binding protein 4 [Source:HGNC carboxypeptidase M [Source:HGNC Symbol;Acc:HGNC:2311]copine II [Source:HGNC Symbol;Acc:HGNC:2315]copine III [Source:HGNC Symbol;Acc:HGNC:2316]cleavage and polyadenylation specific factor 4, 30kDa [Source:HGNC Scarnitine palmitoyltransferase 1A (liver) [Source:HGNC Symbol;Acc:HGNcarnitine palmitoyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:2330]carnitine O-acetyltransferase [Source:HGNC Symbol;Acc:HGNC:2342]crumbs family member 1, photoreceptor morphogenesis associated [ScAMP responsive element binding protein 1 [Source:HGNC Symbol;Acc:cAMP responsive element binding protein 5 [Source:HGNC Symbol;Acc:CREB binding protein [Source:HGNC Symbol;Acc:HGNC:2348]v-crk avian sarcoma virus CT10 oncogene homolog-like [Source:HGNC Scytokine receptor-like factor 1 [Source:HGNC Symbol;Acc:HGNC:2364]cytokine receptor-like factor 3 [Source:HGNC Symbol;Acc:HGNC:17177]carnitine O-octanoyltransferase [Source:HGNC Symbol;Acc:HGNC:2366]cartilage acidic protein 1 [Source:HGNC Symbol;Acc:HGNC:14882]cartilage associated protein [Source:HGNC Symbol;Acc:HGNC:2379]crystallin, alpha B [Source:HGNC Symbol;Acc:HGNC:2389]crystallin, lambda 1 [Source:HGNC Symbol;Acc:HGNC:18246]

CNOT6LCNOT8CNTN2COBLCOG2COG4COL18A1COL1A2COL21A1COL27A1COL4A3

COL5A1COL6A1COL6A2COL6A3COL8A1COL9A2COLEC12COMMD10COMMD5COMTCORO1BCORO1CCOTL1COX15CPCPEB4CPMCPNE2CPNE3CPSF4CPT1ACPT2CRATCRB1CREB1CREB5CREBBPCRKLCRLF1CRLF3CROTCRTAC1CRTAPCRYABCRYL1















































colony stimulating factor 1 (macrophage) [Source:HGNC Symbol;Acc:HGcolony stimulating factor 1 receptor [Source:HGNC Symbol;Acc:HGNC:24c-src tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:2444]casein kinase 1, alpha 1 [Source:HGNC Symbol;Acc:HGNC:2451]casein kinase 1, epsilon [Source:HGNC Symbol;Acc:HGNC:2453]chondroitin sulfate proteoglycan 4 [Source:HGNC Symbol;Acc:HGNC:246cysteine and glycine-rich protein 1 [Source:HGNC Symbol;Acc:HGNC:246cysteine and glycine-rich protein 2 [Source:HGNC Symbol;Acc:HGNC:247C-terminal binding protein 2 [Source:HGNC Symbol;Acc:HGNC:2495]chitobiase, di-N-acetyl- [Source:HGNC Symbol;Acc:HGNC:2496]cystathionine gamma-lyase [Source:HGNC Symbol;Acc:HGNC:2501]catenin (cadherin-associated protein), beta 1, 88kDa [Source:HGNC Sycatenin (cadherin-associated protein), delta 1 [Source:HGNC Symbol;Accatenin (cadherin-associated protein), delta 2 [Source:HGNC Symbol;Accystinosin, lysosomal cystine transporter [Source:HGNC Symbol;Acc:HGcathepsin D [Source:HGNC Symbol;Acc:HGNC:2529]cathepsin F [Source:HGNC Symbol;Acc:HGNC:2531]cathepsin H [Source:HGNC Symbol;Acc:HGNC:2535]cathepsin L [Source:HGNC Symbol;Acc:HGNC:2537]cathepsin Z [Source:HGNC Symbol;Acc:HGNC:2547]cullin 1 [Source:HGNC Symbol;Acc:HGNC:2551]cullin 4A [Source:HGNC Symbol;Acc:HGNC:2554]CWF19-like 2, cell cycle control (S. pombe) [Source:HGNC Symbol;Acc:chemokine (C-X-C motif) ligand 12 [Source:HGNC Symbol;Acc:HGNC:106chemokine (C-X-C motif) ligand 16 [Source:HGNC Symbol;Acc:HGNC:166chemokine (C-X-C motif) ligand 2 [Source:HGNC Symbol;Acc:HGNC:4603]chemokine (C-X-C motif) ligand 5 [Source:HGNC Symbol;Acc:HGNC:10642chemokine (C-X-C motif) receptor 4 [Source:HGNC Symbol;Acc:HGNC:25CXXC finger protein 5 [Source:HGNC Symbol;Acc:HGNC:26943]cytochrome b-245, alpha polypeptide [Source:HGNC Symbol;Acc:HGNC:2cytochrome b reductase 1 [Source:HGNC Symbol;Acc:HGNC:20797]cytochrome P450, family 11, subfamily A, polypeptide 1 [Source:HGNCcytochrome P450, family 1, subfamily B, polypeptide 1 [Source:HGNC Scytochrome P450, family 27, subfamily A, polypeptide 1 [Source:HGNCcytochrome P450, family 2, subfamily J, polypeptide 2 [Source:HGNC Scytochrome P450, family 2, subfamily U, polypeptide 1 [Source:HGNC cytochrome P450, family 39, subfamily A, polypeptide 1 [Source:HGNCcytochrome P450, family 4, subfamily F, polypeptide 3 [Source:HGNC Scysteine-rich, angiogenic inducer, 61 [Source:HGNC Symbol;Acc:HGNC:2dishevelled associated activator of morphogenesis 1 [Source:HGNC Symdishevelled associated activator of morphogenesis 2 [Source:HGNC Symdystroglycan 1 (dystrophin-associated glycoprotein 1) [Source:HGNC Sdeath associated protein 3 [Source:HGNC Symbol;Acc:HGNC:2673]dual adaptor of phosphotyrosine and 3-phosphoinositides [Source:HGNDAZ associated protein 1 [Source:HGNC Symbol;Acc:HGNC:2683]DAZ associated protein 2 [Source:HGNC Symbol;Acc:HGNC:2684]diazepam binding inhibitor (GABA receptor modulator, acyl-CoA bindindihydrolipoamide branched chain transacylase E2 [Source:HGNC Symbo

CSF1CSF1RCSKCSNK1A1CSNK1ECSPG4CSRP1CSRP2CTBP2CTBSCTHCTNNB1CTNND1CTNND2CTNSCTSDCTSFCTSHCTSLCTSZCUL1CUL4ACWF19L2CXCL12CXCL16CXCL2CXCL5CXCR4CXXC5CYBACYBRD1CYP11A1CYP1B1CYP27A1CYP2J2CYP2U1CYP39A1CYP4F3CYR61DAAM1DAAM2DAG1DAP3DAPP1DAZAP1DAZAP2DBIDBT

















































discoidin, CUB and LCCL domain containing 1 [Source:HGNC Symbol;AccDNA cross-link repair 1C [Source:HGNC Symbol;Acc:HGNC:17642]decapping mRNA 1B [Source:HGNC Symbol;Acc:HGNC:24451]dCMP deaminase [Source:HGNC Symbol;Acc:HGNC:2710]dimethylarginine dimethylaminohydrolase 1 [Source:HGNC Symbol;Accdimethylarginine dimethylaminohydrolase 2 [Source:HGNC Symbol;Accdamage-specific DNA binding protein 2, 48kDa [Source:HGNC Symbol;Adiscoidin domain receptor tyrosine kinase 1 [Source:HGNC Symbol;Acc:discoidin domain receptor tyrosine kinase 2 [Source:HGNC Symbol;Acc:DEAD (Asp-Glu-Ala-Asp) box helicase 17 [Source:HGNC Symbol;Acc:HGNDEAD (Asp-Glu-Ala-Asp) box polypeptide 18 [Source:HGNC Symbol;Acc:DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Source:HGNC Symbol;Acc:DEK proto-oncogene [Source:HGNC Symbol;Acc:HGNC:2768]7-dehydrocholesterol reductase [Source:HGNC Symbol;Acc:HGNC:2860]dihydrofolate reductase [Source:HGNC Symbol;Acc:HGNC:2861]dehydrogenase E1 and transketolase domain containing 1 [Source:HGNdicer 1, ribonuclease type III [Source:HGNC Symbol;Acc:HGNC:17098]dispatched homolog 1 (Drosophila) [Source:HGNC Symbol;Acc:HGNC:197deleted in lung and esophageal cancer 1 [Source:HGNC Symbol;Acc:HGNdiscs, large homolog 1 (Drosophila) [Source:HGNC Symbol;Acc:HGNC:290discs, large homolog 5 (Drosophila) [Source:HGNC Symbol;Acc:HGNC:290discs, large (Drosophila) homolog-associated protein 4 [Source:HGNC delta-like 1 (Drosophila) [Source:HGNC Symbol;Acc:HGNC:2908]DNA meiotic recombinase 1 [Source:HGNC Symbol;Acc:HGNC:2927]dynein, axonemal, heavy chain 5 [Source:HGNC Symbol;Acc:HGNC:2950]dynein, axonemal, heavy chain 7 [Source:HGNC Symbol;Acc:HGNC:18661dynein, axonemal, heavy chain 9 [Source:HGNC Symbol;Acc:HGNC:2953]DnaJ (Hsp40) homolog, subfamily B, member 2 [Source:HGNC Symbol;ADnaJ (Hsp40) homolog, subfamily C, member 1 [Source:HGNC Symbol;ADnaJ (Hsp40) homolog, subfamily C, member 10 [Source:HGNC Symbol;dynein, axonemal, light intermediate chain 1 [Source:HGNC Symbol;Accdelta/notch-like EGF repeat containing [Source:HGNC Symbol;Acc:HGNCdynamin 2 [Source:HGNC Symbol;Acc:HGNC:2974]dedicator of cytokinesis 5 [Source:HGNC Symbol;Acc:HGNC:23476]dedicator of cytokinesis 7 [Source:HGNC Symbol;Acc:HGNC:19190]dedicator of cytokinesis 9 [Source:HGNC Symbol;Acc:HGNC:14132]docking protein 1, 62kDa (downstream of tyrosine kinase 1) [Source:HD4, zinc and double PHD fingers, family 3 [Source:HGNC Symbol;Acc:HGdipeptidyl-peptidase 10 (non-functional) [Source:HGNC Symbol;Acc:HGdihydropyrimidine dehydrogenase [Source:HGNC Symbol;Acc:HGNC:301dihydropyrimidinase-like 2 [Source:HGNC Symbol;Acc:HGNC:3014]dihydropyrimidinase-like 3 [Source:HGNC Symbol;Acc:HGNC:3015]dystrobrevin, alpha [Source:HGNC Symbol;Acc:HGNC:3057]dual specificity phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:3064]dual specificity phosphatase 10 [Source:HGNC Symbol;Acc:HGNC:3065]dual specificity phosphatase 16 [Source:HGNC Symbol;Acc:HGNC:17909]deoxyuridine triphosphatase [Source:HGNC Symbol;Acc:HGNC:3078]dishevelled segment polarity protein 2 [Source:HGNC Symbol;Acc:HGNC

DCBLD1DCLRE1CDCP1BDCTDDDAH1DDAH2DDB2DDR1DDR2DDX17DDX18DDX27DEKDHCR7DHFRDHTKD1DICER1DISP1DLEC1DLG1DLG5DLGAP4DLL1DMC1DNAH5DNAH7DNAH9DNAJB2DNAJC1DNAJC10DNALI1DNERDNM2DOCK5DOCK7DOCK9DOK1DPF3DPP10DPYDDPYSL2DPYSL3DTNADUSP1DUSP10DUSP16DUTDVL2

















































dysferlin [Source:HGNC Symbol;Acc:HGNC:3097]E2F transcription factor 6 [Source:HGNC Symbol;Acc:HGNC:3120]E4F transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:3121]enoyl CoA hydratase 1, peroxisomal [Source:HGNC Symbol;Acc:HGNC:31extracellular matrix protein 2, female organ and adipocyte specific [Sendothelin receptor type A [Source:HGNC Symbol;Acc:HGNC:3179]embryonic ectoderm development [Source:HGNC Symbol;Acc:HGNC:318EGF containing fibulin-like extracellular matrix protein 1 [Source:HGNEGF containing fibulin-like extracellular matrix protein 2 [Source:HGNEF-hand domain (C-terminal) containing 1 [Source:HGNC Symbol;Acc:Hephrin-A1 [Source:HGNC Symbol;Acc:HGNC:3221]ephrin-A4 [Source:HGNC Symbol;Acc:HGNC:3224]embryonal Fyn-associated substrate [Source:HGNC Symbol;Acc:HGNC:16epidermal growth factor receptor [Source:HGNC Symbol;Acc:HGNC:3236egl-9 family hypoxia-inducible factor 3 [Source:HGNC Symbol;Acc:HGNCEH-domain containing 1 [Source:HGNC Symbol;Acc:HGNC:3242]ets homologous factor [Source:HGNC Symbol;Acc:HGNC:3246]

EIF1AY eukaryotic translation initiation factor 1A, Y-linked [Source:HGNC Symbeukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa [Soeukaryotic translation initiation factor 4E binding protein 2 [Source:Heukaryotic translation initiation factor 4 gamma, 1 [Source:HGNC SymbE74-like factor 1 (ets domain transcription factor) [Source:HGNC SymboE74-like factor 2 (ets domain transcription factor) [Source:HGNC Symbo

ELF4 E74-like factor 4 (ets domain transcription factor) [Source:HGNC Symboelongation factor, RNA polymerase II, 2 [Source:HGNC Symbol;Acc:HGNCelastin [Source:HGNC Symbol;Acc:HGNC:3327]ELOVL fatty acid elongase 7 [Source:HGNC Symbol;Acc:HGNC:26292]elongator acetyltransferase complex subunit 4 [Source:HGNC Symbol;Aepithelial membrane protein 1 [Source:HGNC Symbol;Acc:HGNC:3333]epithelial membrane protein 2 [Source:HGNC Symbol;Acc:HGNC:3334]epithelial membrane protein 3 [Source:HGNC Symbol;Acc:HGNC:3335]empty spiracles homeobox 2 [Source:HGNC Symbol;Acc:HGNC:3341]enabled homolog (Drosophila) [Source:HGNC Symbol;Acc:HGNC:18271]ectonucleoside triphosphate diphosphohydrolase 1 [Source:HGNC Symbectonucleoside triphosphate diphosphohydrolase 2 [Source:HGNC SymbE1A binding protein p300 [Source:HGNC Symbol;Acc:HGNC:3373]E1A binding protein p400 [Source:HGNC Symbol;Acc:HGNC:11958]erythrocyte membrane protein band 4.1 like 5 [Source:HGNC Symbol;Aenhancer of polycomb homolog 1 (Drosophila) [Source:HGNC Symbol;Aenhancer of polycomb homolog 2 (Drosophila) [Source:HGNC Symbol;Aepoxide hydrolase 1, microsomal (xenobiotic) [Source:HGNC Symbol;Acepoxide hydrolase 2, cytoplasmic [Source:HGNC Symbol;Acc:HGNC:3402epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) [Soerythropoietin receptor [Source:HGNC Symbol;Acc:HGNC:3416]epidermal growth factor receptor pathway substrate 8 [Source:HGNC Serb-b2 receptor tyrosine kinase 2 [Source:HGNC Symbol;Acc:HGNC:3430erbb2 interacting protein [Source:HGNC Symbol;Acc:HGNC:15842]erb-b2 receptor tyrosine kinase 3 [Source:HGNC Symbol;Acc:HGNC:3431

DYSFE2F6E4F1ECH1ECM2EDNRAEEDEFEMP1EFEMP2EFHC1EFNA1EFNA4EFSEGFREGLN3EHD1EHF

EIF2B4EIF4EBP2EIF4G1ELF1ELF2

ELL2ELNELOVL7ELP4EMP1EMP2EMP3EMX2ENAHENTPD1ENTPD2EP300EP400EPB41L5EPC1EPC2EPHX1EPHX2EPM2AEPOREPS8ERBB2ERBB2IPERBB3















































excision repair cross-complementation group 1 [Source:HGNC Symbol;Aexcision repair cross-complementation group 5 [Source:HGNC Symbol;Aesterase D [Source:HGNC Symbol;Acc:HGNC:3465]electron-transferring-flavoprotein dehydrogenase [Source:HGNC Symbov-ets avian erythroblastosis virus E26 oncogene homolog 1 [Source:HGEllis van Creveld syndrome [Source:HGNC Symbol;Acc:HGNC:3497]EWS RNA-binding protein 1 [Source:HGNC Symbol;Acc:HGNC:3508]EYA transcriptional coactivator and phosphatase 2 [Source:HGNC SymboEYA transcriptional coactivator and phosphatase 3 [Source:HGNC Symboenhancer of zeste 1 polycomb repressive complex 2 subunit [Source:Hcoagulation factor II (thrombin) receptor [Source:HGNC Symbol;Acc:HGcoagulation factor II (thrombin) receptor-like 1 [Source:HGNC Symbol;coagulation factor V (proaccelerin, labile factor) [Source:HGNC Symbolfatty acid binding protein 5 (psoriasis-associated) [Source:HGNC Symbofatty acid desaturase 1 [Source:HGNC Symbol;Acc:HGNC:3574]fatty acid desaturase 2 [Source:HGNC Symbol;Acc:HGNC:3575]fumarylacetoacetate hydrolase (fumarylacetoacetase) [Source:HGNC SFas apoptotic inhibitory molecule [Source:HGNC Symbol;Acc:HGNC:1870

FAM3A family with sequence similarity 3, member A [Source:HGNC Symbol;AccFanconi anemia, complementation group L [Source:HGNC Symbol;Acc:HFERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocytefibulin 1 [Source:HGNC Symbol;Acc:HGNC:3600]fibrillin 1 [Source:HGNC Symbol;Acc:HGNC:3603]F-box and leucine-rich repeat protein 12 [Source:HGNC Symbol;Acc:HGNF-box and leucine-rich repeat protein 7 [Source:HGNC Symbol;Acc:HGNCF-box protein 30 [Source:HGNC Symbol;Acc:HGNC:15600]F-box protein 32 [Source:HGNC Symbol;Acc:HGNC:16731]F-box protein 8 [Source:HGNC Symbol;Acc:HGNC:13587]Fc fragment of IgG, receptor, transporter, alpha [Source:HGNC Symbol;FCH and double SH3 domains 1 [Source:HGNC Symbol;Acc:HGNC:25463]farnesyl-diphosphate farnesyltransferase 1 [Source:HGNC Symbol;Acc:ferredoxin reductase [Source:HGNC Symbol;Acc:HGNC:3642]fasciculation and elongation protein zeta 2 (zygin II) [Source:HGNC SymFYVE, RhoGEF and PH domain containing 4 [Source:HGNC Symbol;Acc:Hfibroblast growth factor 1 (acidic) [Source:HGNC Symbol;Acc:HGNC:3665fibroblast growth factor 2 (basic) [Source:HGNC Symbol;Acc:HGNC:3676]fibroblast growth factor receptor 1 [Source:HGNC Symbol;Acc:HGNC:368FGFR1 oncogene partner 2 [Source:HGNC Symbol;Acc:HGNC:23098]fibroblast growth factor receptor 3 [Source:HGNC Symbol;Acc:HGNC:369fibroblast growth factor receptor-like 1 [Source:HGNC Symbol;Acc:HGNCfibrinogen gamma chain [Source:HGNC Symbol;Acc:HGNC:3694]FGR proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;fidgetin [Source:HGNC Symbol;Acc:HGNC:13285]FK506 binding protein 10, 65 kDa [Source:HGNC Symbol;Acc:HGNC:1816FK506 binding protein 5 [Source:HGNC Symbol;Acc:HGNC:3721]FK506 binding protein 9, 63 kDa [Source:HGNC Symbol;Acc:HGNC:3725]flightless I homolog (Drosophila) [Source:HGNC Symbol;Acc:HGNC:3750]

FLNA filamin A, alpha [Source:HGNC Symbol;Acc:HGNC:3754]

ERCC1ERCC5ESDETFDHETS1EVCEWSR1EYA2EYA3EZH1F2RF2RL1F5FABP5FADS1FADS2FAHFAIM

FANCLFARP1FBLN1FBN1FBXL12FBXL7FBXO30FBXO32FBXO8FCGRTFCHSD1FDFT1FDXRFEZ2FGD4FGF1FGF2FGFR1FGFR1OP2FGFR3FGFRL1FGGFGRFIGNFKBP10FKBP5FKBP9FLII















































filamin B, beta [Source:HGNC Symbol;Acc:HGNC:3755]filamin C, gamma [Source:HGNC Symbol;Acc:HGNC:3756]formin-like 2 [Source:HGNC Symbol;Acc:HGNC:18267]formin-like 3 [Source:HGNC Symbol;Acc:HGNC:23698]flavin containing monooxygenase 2 (non-functional) [Source:HGNC Symformin binding protein 1 [Source:HGNC Symbol;Acc:HGNC:17069]farnesyltransferase, CAAX box, alpha [Source:HGNC Symbol;Acc:HGNC:3forkhead box D1 [Source:HGNC Symbol;Acc:HGNC:3802]frequently rearranged in advanced T-cell lymphomas 1 [Source:HGNC SFERM domain containing 3 [Source:HGNC Symbol;Acc:HGNC:24125]FERM and PDZ domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28follistatin-like 1 [Source:HGNC Symbol;Acc:HGNC:3972]follistatin-like 3 (secreted glycoprotein) [Source:HGNC Symbol;Acc:HGNCFtsJ homolog 3 (E. coli) [Source:HGNC Symbol;Acc:HGNC:17136]far upstream element (FUSE) binding protein 3 [Source:HGNC Symbol;Afucokinase [Source:HGNC Symbol;Acc:HGNC:29500]fragile X mental retardation, autosomal homolog 1 [Source:HGNC SymbFXYD domain containing ion transport regulator 1 [Source:HGNC SymboFXYD domain containing ion transport regulator 3 [Source:HGNC SymboFXYD domain containing ion transport regulator 5 [Source:HGNC SymboFYN binding protein [Source:HGNC Symbol;Acc:HGNC:4036]FYVE and coiled-coil domain containing 1 [Source:HGNC Symbol;Acc:HGFYN proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;frizzled class receptor 6 [Source:HGNC Symbol;Acc:HGNC:4044]G0/G1 switch 2 [Source:HGNC Symbol;Acc:HGNC:30229]glucosidase, alpha; acid [Source:HGNC Symbol;Acc:HGNC:4065]GRB2-associated binding protein 1 [Source:HGNC Symbol;Acc:HGNC:406GRB2-associated binding protein 2 [Source:HGNC Symbol;Acc:HGNC:144gamma-aminobutyric acid (GABA) A receptor, gamma 1 [Source:HGNC Sgrowth arrest and DNA-damage-inducible, gamma [Source:HGNC Symbogalactosylceramidase [Source:HGNC Symbol;Acc:HGNC:4115]galactose mutarotase (aldose 1-epimerase) [Source:HGNC Symbol;Acc:galactosamine (N-acetyl)-6-sulfatase [Source:HGNC Symbol;Acc:HGNC:4polypeptide N-acetylgalactosaminyltransferase 10 [Source:HGNC Symbopolypeptide N-acetylgalactosaminyltransferase 2 [Source:HGNC Symbolpolypeptide N-acetylgalactosaminyltransferase 3 [Source:HGNC Symbolpolypeptide N-acetylgalactosaminyltransferase 4 [Source:HGNC Symbolphosphoribosylglycinamide formyltransferase, phosphoribosylglycinamgrowth arrest-specific 1 [Source:HGNC Symbol;Acc:HGNC:4165]growth arrest-specific 8 [Source:HGNC Symbol;Acc:HGNC:4166]glycine amidinotransferase (L-arginine:glycine amidinotransferase) [Sglucan (1,4-alpha-), branching enzyme 1 [Source:HGNC Symbol;Acc:HGNguanylate binding protein 1, interferon-inducible [Source:HGNC Symbolguanylate binding protein 2, interferon-inducible [Source:HGNC Symbolguanylate binding protein 3 [Source:HGNC Symbol;Acc:HGNC:4184]glutaryl-CoA dehydrogenase [Source:HGNC Symbol;Acc:HGNC:4189]GCN1 general control of amino-acid synthesis 1-like 1 (yeast) [Sourcegrowth differentiation factor 1 [Source:HGNC Symbol;Acc:HGNC:4214]

FLNBFLNCFMNL2FMNL3FMO2FNBP1FNTAFOXD1FRAT1FRMD3FRMPD2FSTL1FSTL3FTSJ3FUBP3FUKFXR1FXYD1FXYD3FXYD5FYBFYCO1FYNFZD6G0S2GAAGAB1GAB2GABRG1GADD45GGALCGALMGALNSGALNT10GALNT2GALNT3GALNT4GARTGAS1GAS8GATMGBE1GBP1GBP2GBP3GCDHGCN1L1GDF1

















































growth differentiation factor 10 [Source:HGNC Symbol;Acc:HGNC:4215]GTP binding protein overexpressed in skeletal muscle [Source:HGNC Syglial fibrillary acidic protein [Source:HGNC Symbol;Acc:HGNC:4235]golgi-associated, gamma adaptin ear containing, ARF binding protein gap junction protein, alpha 1, 43kDa [Source:HGNC Symbol;Acc:HGNC:42gap junction protein, alpha 4, 37kDa [Source:HGNC Symbol;Acc:HGNC:42G kinase anchoring protein 1 [Source:HGNC Symbol;Acc:HGNC:17496]golgi glycoprotein 1 [Source:HGNC Symbol;Acc:HGNC:4316]GLI family zinc finger 2 [Source:HGNC Symbol;Acc:HGNC:4318]GLI pathogenesis-related 1 [Source:HGNC Symbol;Acc:HGNC:17001]GLIS family zinc finger 2 [Source:HGNC Symbol;Acc:HGNC:29450]glycolipid transfer protein [Source:HGNC Symbol;Acc:HGNC:24867]glioma tumor suppressor candidate region gene 2 [Source:HGNC SymboGM2 ganglioside activator [Source:HGNC Symbol;Acc:HGNC:4367]glia maturation factor, beta [Source:HGNC Symbol;Acc:HGNC:4373]geminin, DNA replication inhibitor [Source:HGNC Symbol;Acc:HGNC:174GDP-mannose pyrophosphorylase A [Source:HGNC Symbol;Acc:HGNC:22guanosine monophosphate reductase [Source:HGNC Symbol;Acc:HGNC:guanine nucleotide binding protein (G protein) alpha 12 [Source:HGNCguanine nucleotide binding protein (G protein), alpha 13 [Source:HGNCguanine nucleotide binding protein (G protein), alpha inhibiting activiGNAS complex locus [Source:HGNC Symbol;Acc:HGNC:4392]guanine nucleotide binding protein (G protein), beta polypeptide 4 [Sguanine nucleotide binding protein (G protein), gamma 11 [Source:HGguanine nucleotide binding protein (G protein), gamma 12 [Source:HGglucosamine (N-acetyl)-6-sulfatase [Source:HGNC Symbol;Acc:HGNC:442golgi-associated PDZ and coiled-coil motif containing [Source:HGNC Sygolgi reassembly stacking protein 1, 65kDa [Source:HGNC Symbol;Acc:Hgolgi SNAP receptor complex member 1 [Source:HGNC Symbol;Acc:HGNC

GPC4 glypican 4 [Source:HGNC Symbol;Acc:HGNC:4452]glypican 6 [Source:HGNC Symbol;Acc:HGNC:4454]

GPM6B glycoprotein M6B [Source:HGNC Symbol;Acc:HGNC:4461]G protein-coupled receptor 107 [Source:HGNC Symbol;Acc:HGNC:17830]G protein-coupled receptor 146 [Source:HGNC Symbol;Acc:HGNC:21718]G protein-coupled receptor 161 [Source:HGNC Symbol;Acc:HGNC:23694]G protein-coupled receptor 17 [Source:HGNC Symbol;Acc:HGNC:4471]G protein-coupled receptor, class C, group 5, member B [Source:HGNCG protein-coupled receptor, class C, group 5, member C [Source:HGNCG protein pathway suppressor 2 [Source:HGNC Symbol;Acc:HGNC:4550]G-protein signaling modulator 1 [Source:HGNC Symbol;Acc:HGNC:17858glutamic-pyruvate transaminase (alanine aminotransferase) [Source:Hglutathione peroxidase 1 [Source:HGNC Symbol;Acc:HGNC:4553]glutamate receptor, ionotropic, N-methyl D-aspartate 2C [Source:HGNgranulin [Source:HGNC Symbol;Acc:HGNC:4601]growth hormone regulated TBC protein 1 [Source:HGNC Symbol;Acc:HGgelsolin [Source:HGNC Symbol;Acc:HGNC:4620]glutathione S-transferase pi 1 [Source:HGNC Symbol;Acc:HGNC:4638]general transcription factor IIE, polypeptide 1, alpha 56kDa [Source:H

GDF10GEMGFAPGGA1GJA1GJA4GKAP1GLG1GLI2GLIPR1GLIS2GLTPGLTSCR2GM2AGMFBGMNNGMPPAGMPRGNA12GNA13GNAI3GNASGNB4GNG11GNG12GNSGOPCGORASP1GOSR1

GPC6

GPR107GPR146GPR161GPR17GPRC5BGPRC5CGPS2GPSM1GPTGPX1GRIN2CGRNGRTP1GSNGSTP1GTF2E1















































general transcription factor IIH, polypeptide 3, 34kDa [Source:HGNC Sgeneral transcription factor IIi [Source:HGNC Symbol;Acc:HGNC:4659]general transcription factor IIIC, polypeptide 5, 63kDa [Source:HGNC SG-2 and S-phase expressed 1 [Source:HGNC Symbol;Acc:HGNC:13698]glucuronidase, beta [Source:HGNC Symbol;Acc:HGNC:4696]

GYG2 glycogenin 2 [Source:HGNC Symbol;Acc:HGNC:4700]glycogen synthase 1 (muscle) [Source:HGNC Symbol;Acc:HGNC:4706]H2A histone family, member V [Source:HGNC Symbol;Acc:HGNC:20664]H2A histone family, member X [Source:HGNC Symbol;Acc:HGNC:4739]H2A histone family, member Y [Source:HGNC Symbol;Acc:HGNC:4740]H3 histone, family 3A [Source:HGNC Symbol;Acc:HGNC:4764]H3 histone, family 3B (H3.3B) [Source:HGNC Symbol;Acc:HGNC:4765]hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) [Sourchydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydrhydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydrHMG-box transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:23200]hematopoietic cell-specific Lyn substrate 1 [Source:HGNC Symbol;Acc:Hhistone deacetylase 1 [Source:HGNC Symbol;Acc:HGNC:4852]histone deacetylase 11 [Source:HGNC Symbol;Acc:HGNC:19086]histone deacetylase 4 [Source:HGNC Symbol;Acc:HGNC:14063]hepatoma-derived growth factor [Source:HGNC Symbol;Acc:HGNC:4856]heme binding protein 2 [Source:HGNC Symbol;Acc:HGNC:15716]HECT domain containing E3 ubiquitin protein ligase 1 [Source:HGNC Sy

HEPH hephaestin [Source:HGNC Symbol;Acc:HGNC:4866]hes family bHLH transcription factor 6 [Source:HGNC Symbol;Acc:HGNC:hes-related family bHLH transcription factor with YRPW motif-like [Sohemochromatosis [Source:HGNC Symbol;Acc:HGNC:4886]HERV-H LTR-associating 3 [Source:HGNC Symbol;Acc:HGNC:4906]3-hydroxyisobutyryl-CoA hydrolase [Source:HGNC Symbol;Acc:HGNC:490hypoxia inducible factor 3, alpha subunit [Source:HGNC Symbol;Acc:HGhuntingtin interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:4913]huntingtin interacting protein 1 related [Source:HGNC Symbol;Acc:HGNChomeodomain interacting protein kinase 2 [Source:HGNC Symbol;Acc:Hhomeodomain interacting protein kinase 3 [Source:HGNC Symbol;Acc:HHIRA interacting protein 3 [Source:HGNC Symbol;Acc:HGNC:4917]histone cluster 1, H1c [Source:HGNC Symbol;Acc:HGNC:4716]histone cluster 1, H2ac [Source:HGNC Symbol;Acc:HGNC:4733]histone cluster 1, H2bc [Source:HGNC Symbol;Acc:HGNC:4757]histone cluster 1, H3d [Source:HGNC Symbol;Acc:HGNC:4767]histone cluster 2, H2be [Source:HGNC Symbol;Acc:HGNC:4760]major histocompatibility complex, class I, A [Source:HGNC Symbol;Acc:major histocompatibility complex, class I, C [Source:HGNC Symbol;Acc:major histocompatibility complex, class II, DM alpha [Source:HGNC Symmajor histocompatibility complex, class II, DP beta 1 [Source:HGNC Symajor histocompatibility complex, class II, DQ beta 1 [Source:HGNC Symajor histocompatibility complex, class II, DR beta 1 [Source:HGNC Symajor histocompatibility complex, class II, DR beta 5 [Source:HGNC Symajor histocompatibility complex, class I, E [Source:HGNC Symbol;Acc:

GTF2H3GTF2IGTF3C5GTSE1GUSB

GYS1H2AFVH2AFXH2AFYH3F3AH3F3BH6PDHADHAHADHBHBP1HCLS1HDAC1HDAC11HDAC4HDGFHEBP2HECTD1

HES6HEYLHFEHHLA3HIBCHHIF3AHIP1HIP1RHIPK2HIPK3HIRIP3HIST1H1CHIST1H2ACHIST1H2BCHIST1H3DHIST2H2BEHLA-AHLA-CHLA-DMAHLA-DPB1HLA-DQB1HLA-DRB1HLA-DRB5HLA-E















































major histocompatibility complex, class I, G [Source:HGNC Symbol;Acc:high mobility group 20B [Source:HGNC Symbol;Acc:HGNC:5002]high mobility group box 1 [Source:HGNC Symbol;Acc:HGNC:4983]high mobility group box 2 [Source:HGNC Symbol;Acc:HGNC:5000]

HMGB3 high mobility group box 3 [Source:HGNC Symbol;Acc:HGNC:5004]3-hydroxymethyl-3-methylglutaryl-CoA lyase [Source:HGNC Symbol;Acchigh mobility group nucleosome binding domain 1 [Source:HGNC Symbohigh mobility group nucleosomal binding domain 3 [Source:HGNC Symbhistamine N-methyltransferase [Source:HGNC Symbol;Acc:HGNC:5028]homer scaffolding protein 3 [Source:HGNC Symbol;Acc:HGNC:17514]homeobox A10 [Source:HGNC Symbol;Acc:HGNC:5100]homeobox A7 [Source:HGNC Symbol;Acc:HGNC:5108]homeobox C10 [Source:HGNC Symbol;Acc:HGNC:5122]homeobox C6 [Source:HGNC Symbol;Acc:HGNC:5128]homeobox D10 [Source:HGNC Symbol;Acc:HGNC:5133]hippocalcin-like 1 [Source:HGNC Symbol;Acc:HGNC:5145]haptoglobin-related protein [Source:HGNC Symbol;Acc:HGNC:5156]Hermansky-Pudlak syndrome 3 [Source:HGNC Symbol;Acc:HGNC:15597]hydroxysteroid (17-beta) dehydrogenase 3 [Source:HGNC Symbol;Acc:Hhydroxysteroid (17-beta) dehydrogenase 7 [Source:HGNC Symbol;Acc:Hheat shock 70kD protein 12B [Source:HGNC Symbol;Acc:HGNC:16193]heat shock 70kDa protein 1A [Source:HGNC Symbol;Acc:HGNC:5232]heat shock 70kDa protein 1B [Source:HGNC Symbol;Acc:HGNC:5233]heat shock 70kDa protein 2 [Source:HGNC Symbol;Acc:HGNC:5235]heat shock 27kDa protein 1 [Source:HGNC Symbol;Acc:HGNC:5246]heat shock 27kDa protein 2 [Source:HGNC Symbol;Acc:HGNC:5247]heat shock protein, alpha-crystallin-related, B6 [Source:HGNC Symbol;heat shock 22kDa protein 8 [Source:HGNC Symbol;Acc:HGNC:30171]HSPB (heat shock 27kDa) associated protein 1 [Source:HGNC Symbol;AcHUS1 checkpoint homolog (S. pombe) [Source:HGNC Symbol;Acc:HGNC:huntingtin interacting protein K [Source:HGNC Symbol;Acc:HGNC:18418]intercellular adhesion molecule 2 [Source:HGNC Symbol;Acc:HGNC:5345inhibitor of DNA binding 1, dominant negative helix-loop-helix proteiinhibitor of DNA binding 2, dominant negative helix-loop-helix proteiinhibitor of DNA binding 3, dominant negative helix-loop-helix proteiinhibitor of DNA binding 4, dominant negative helix-loop-helix proteiisocitrate dehydrogenase 1 (NADP+), soluble [Source:HGNC Symbol;Accisopentenyl-diphosphate delta isomerase 1 [Source:HGNC Symbol;Acc:immediate early response 3 [Source:HGNC Symbol;Acc:HGNC:5392]immediate early response 5 [Source:HGNC Symbol;Acc:HGNC:5393]interferon, gamma-inducible protein 16 [Source:HGNC Symbol;Acc:HGNinterferon-induced protein 35 [Source:HGNC Symbol;Acc:HGNC:5399]interferon-induced protein with tetratricopeptide repeats 2 [Source:interferon induced transmembrane protein 2 [Source:HGNC Symbol;Accinterferon induced transmembrane protein 3 [Source:HGNC Symbol;Accinterferon gamma receptor 1 [Source:HGNC Symbol;Acc:HGNC:5439]interferon-related developmental regulator 1 [Source:HGNC Symbol;Acinterferon-related developmental regulator 2 [Source:HGNC Symbol;Ac

HLA-GHMG20BHMGB1HMGB2

HMGCLHMGN1HMGN3HNMTHOMER3HOXA10HOXA7HOXC10HOXC6HOXD10HPCAL1HPRHPS3HSD17B3HSD17B7HSPA12BHSPA1AHSPA1BHSPA2HSPB1HSPB2HSPB6HSPB8HSPBAP1HUS1HYPKICAM2ID1ID2ID3ID4IDH1IDI1IER3IER5IFI16IFI35IFIT2IFITM2IFITM3IFNGR1IFRD1IFRD2
















































insulin-like growth factor 2 receptor [Source:HGNC Symbol;Acc:HGNC:54insulin-like growth factor binding protein 3 [Source:HGNC Symbol;Acc:insulin-like growth factor binding protein 5 [Source:HGNC Symbol;Acc:insulin-like growth factor binding protein 7 [Source:HGNC Symbol;Acc:

IGSF1 immunoglobulin superfamily, member 1 [Source:HGNC Symbol;Acc:HGNinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase

IL13RA1 interleukin 13 receptor, alpha 1 [Source:HGNC Symbol;Acc:HGNC:5974]interleukin 15 [Source:HGNC Symbol;Acc:HGNC:5977]interleukin 17B [Source:HGNC Symbol;Acc:HGNC:5982]interleukin 17D [Source:HGNC Symbol;Acc:HGNC:5984]interleukin 17 receptor B [Source:HGNC Symbol;Acc:HGNC:18015]interleukin 17 receptor C [Source:HGNC Symbol;Acc:HGNC:18358]interleukin 1, alpha [Source:HGNC Symbol;Acc:HGNC:5991]interleukin 20 receptor, alpha [Source:HGNC Symbol;Acc:HGNC:6003]interleukin 4 receptor [Source:HGNC Symbol;Acc:HGNC:6015]interleukin 6 receptor [Source:HGNC Symbol;Acc:HGNC:6019]interleukin 6 signal transducer [Source:HGNC Symbol;Acc:HGNC:6021]integrin-linked kinase [Source:HGNC Symbol;Acc:HGNC:6040]integrin-linked kinase-associated serine/threonine phosphatase [Sourinositol(myo)-1(or 4)-monophosphatase 2 [Source:HGNC Symbol;Acc:HGinhibitor of growth family, member 3 [Source:HGNC Symbol;Acc:HGNC:1inhibin, beta B [Source:HGNC Symbol;Acc:HGNC:6067]indolethylamine N-methyltransferase [Source:HGNC Symbol;Acc:HGNC:6inositol polyphosphate-5-phosphatase, 75kDa [Source:HGNC Symbol;Acinositol polyphosphate phosphatase-like 1 [Source:HGNC Symbol;Acc:Hinsulin receptor [Source:HGNC Symbol;Acc:HGNC:6091]importin 8 [Source:HGNC Symbol;Acc:HGNC:9853]intracisternal A particle-promoted polypeptide [Source:HGNC Symbol;AIQ motif containing GTPase activating protein 1 [Source:HGNC Symbol;

IRAK1 interleukin-1 receptor-associated kinase 1 [Source:HGNC Symbol;Acc:Hinterferon regulatory factor 2 [Source:HGNC Symbol;Acc:HGNC:6117]interferon regulatory factor 2 binding protein 2 [Source:HGNC Symbol;interferon regulatory factor 3 [Source:HGNC Symbol;Acc:HGNC:6118]interferon regulatory factor 7 [Source:HGNC Symbol;Acc:HGNC:6122]insulin receptor substrate 2 [Source:HGNC Symbol;Acc:HGNC:6126]iroquois homeobox 3 [Source:HGNC Symbol;Acc:HGNC:14360]integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) [Source:integrin, alpha 6 [Source:HGNC Symbol;Acc:HGNC:6142]integrin, alpha 7 [Source:HGNC Symbol;Acc:HGNC:6143]integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD2integrin, beta 4 [Source:HGNC Symbol;Acc:HGNC:6158]integrin, beta 5 [Source:HGNC Symbol;Acc:HGNC:6160]integrin, beta 8 [Source:HGNC Symbol;Acc:HGNC:6163]integral membrane protein 2C [Source:HGNC Symbol;Acc:HGNC:6175]inositol-tetrakisphosphate 1-kinase [Source:HGNC Symbol;Acc:HGNC:61inositol-trisphosphate 3-kinase B [Source:HGNC Symbol;Acc:HGNC:6179]intersectin 1 (SH3 domain protein) [Source:HGNC Symbol;Acc:HGNC:618intersectin 2 [Source:HGNC Symbol;Acc:HGNC:6184]

IGF2RIGFBP3IGFBP5IGFBP7

IKBKB

IL15IL17BIL17DIL17RBIL17RCIL1AIL20RAIL4RIL6RIL6STILKILKAPIMPA2ING3INHBBINMTINPP5BINPPL1INSRIPO8IPPIQGAP1

IRF2IRF2BP2IRF3IRF7IRS2IRX3ITGA2ITGA6ITGA7ITGB1ITGB4ITGB5ITGB8ITM2CITPK1ITPKBITSN1ITSN2














































Janus kinase 1 [Source:HGNC Symbol;Acc:HGNC:6190]junctional adhesion molecule 2 [Source:HGNC Symbol;Acc:HGNC:14686]Jun dimerization protein 2 [Source:HGNC Symbol;Acc:HGNC:17546]jumonji domain containing 1C [Source:HGNC Symbol;Acc:HGNC:12313]JRK-like [Source:HGNC Symbol;Acc:HGNC:6200]jun proto-oncogene [Source:HGNC Symbol;Acc:HGNC:6204]junction plakoglobin [Source:HGNC Symbol;Acc:HGNC:6207]katanin p60 (ATPase containing) subunit A 1 [Source:HGNC Symbol;Acc

KCND1 potassium channel, voltage gated Shal related subfamily D, member 1potassium channel, inwardly rectifying subfamily J, member 10 [Sourcpotassium channel, inwardly rectifying subfamily J, member 3 [Sourcepotassium channel, inwardly rectifying subfamily J, member 8 [Sourcepotassium channel subfamily M regulatory beta subunit 4 [Source:HGNpotassium channel, calcium activated intermediate/small conductancepotassium channel, calcium activated intermediate/small conductancepotassium channel regulator [Source:HGNC Symbol;Acc:HGNC:18893]potassium channel tetramerization domain containing 11 [Source:HGNpotassium channel tetramerization domain containing 15 [Source:HGNpotassium channel tetramerization domain containing 6 [Source:HGNCkelch-like ECH-associated protein 1 [Source:HGNC Symbol;Acc:HGNC:23KIAA0020 [Source:HGNC Symbol;Acc:HGNC:29676]KIAA0355 [Source:HGNC Symbol;Acc:HGNC:29016]KIAA0391 [Source:HGNC Symbol;Acc:HGNC:19958]KIAA0556 [Source:HGNC Symbol;Acc:HGNC:29068]KIAA0930 [Source:HGNC Symbol;Acc:HGNC:1314]KIAA1033 [Source:HGNC Symbol;Acc:HGNC:29174]KIAA1143 [Source:HGNC Symbol;Acc:HGNC:29198]KIAA1211 [Source:HGNC Symbol;Acc:HGNC:29219]KIAA1598 [Source:HGNC Symbol;Acc:HGNC:29319]KIAA1683 [Source:HGNC Symbol;Acc:HGNC:29350]KIAA1919 [Source:HGNC Symbol;Acc:HGNC:21053]KIAA1958 [Source:HGNC Symbol;Acc:HGNC:23427]KIAA2026 [Source:HGNC Symbol;Acc:HGNC:23378]kinesin family member 13B [Source:HGNC Symbol;Acc:HGNC:14405]kinesin family member 1B [Source:HGNC Symbol;Acc:HGNC:16636]kinesin family member 1C [Source:HGNC Symbol;Acc:HGNC:6317]kinesin family member 26A [Source:HGNC Symbol;Acc:HGNC:20226]kinesin family member 5B [Source:HGNC Symbol;Acc:HGNC:6324]kinesin family member 9 [Source:HGNC Symbol;Acc:HGNC:16666]Kruppel-like factor 12 [Source:HGNC Symbol;Acc:HGNC:6346]Kruppel-like factor 13 [Source:HGNC Symbol;Acc:HGNC:13672]Kruppel-like factor 15 [Source:HGNC Symbol;Acc:HGNC:14536]Kruppel-like factor 2 [Source:HGNC Symbol;Acc:HGNC:6347]Kruppel-like factor 3 (basic) [Source:HGNC Symbol;Acc:HGNC:16516]Kruppel-like factor 7 (ubiquitous) [Source:HGNC Symbol;Acc:HGNC:6350]kelch-like family member 5 [Source:HGNC Symbol;Acc:HGNC:6356]kelch-like family member 8 [Source:HGNC Symbol;Acc:HGNC:18644]karyopherin (importin) beta 1 [Source:HGNC Symbol;Acc:HGNC:6400]

JAK1JAM2JDP2JMJD1CJRKLJUNJUPKATNA1

KCNJ10KCNJ3KCNJ8KCNMB4KCNN2KCNN3KCNRGKCTD11KCTD15KCTD6KEAP1KIAA0020KIAA0355KIAA0391KIAA0556KIAA0930KIAA1033KIAA1143KIAA1211KIAA1598KIAA1683KIAA1919KIAA1958KIAA2026KIF13BKIF1BKIF1CKIF26AKIF5BKIF9KLF12KLF13KLF15KLF2KLF3KLF7KLHL5KLHL8KPNB1
















































keratin 8, type II [Source:HGNC Symbol;Acc:HGNC:6446]keratinocyte associated protein 2 [Source:HGNC Symbol;Acc:HGNC:2894kinectin 1 (kinesin receptor) [Source:HGNC Symbol;Acc:HGNC:6467]laminin, alpha 1 [Source:HGNC Symbol;Acc:HGNC:6481]laminin, alpha 2 [Source:HGNC Symbol;Acc:HGNC:6482]laminin, alpha 4 [Source:HGNC Symbol;Acc:HGNC:6484]laminin, alpha 5 [Source:HGNC Symbol;Acc:HGNC:6485]laminin, beta 2 (laminin S) [Source:HGNC Symbol;Acc:HGNC:6487]laminin, gamma 1 (formerly LAMB2) [Source:HGNC Symbol;Acc:HGNC:64lysosomal-associated membrane protein 1 [Source:HGNC Symbol;Acc:H

LAMP2 lysosomal-associated membrane protein 2 [Source:HGNC Symbol;Acc:Hlysosomal protein transmembrane 4 alpha [Source:HGNC Symbol;Acc:Hlysosomal protein transmembrane 4 beta [Source:HGNC Symbol;Acc:HGlysosomal protein transmembrane 5 [Source:HGNC Symbol;Acc:HGNC:29leucyl-tRNA synthetase [Source:HGNC Symbol;Acc:HGNC:6512]large tumor suppressor kinase 1 [Source:HGNC Symbol;Acc:HGNC:6514]large tumor suppressor kinase 2 [Source:HGNC Symbol;Acc:HGNC:6515]lamin B receptor [Source:HGNC Symbol;Acc:HGNC:6518]lecithin-cholesterol acyltransferase [Source:HGNC Symbol;Acc:HGNC:652low density lipoprotein receptor [Source:HGNC Symbol;Acc:HGNC:6547]lymphoid enhancer-binding factor 1 [Source:HGNC Symbol;Acc:HGNC:65leptin receptor [Source:HGNC Symbol;Acc:HGNC:6554]LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase [Sourclectin, galactoside-binding, soluble, 1 [Source:HGNC Symbol;Acc:HGNC:6lectin, galactoside-binding, soluble, 3 [Source:HGNC Symbol;Acc:HGNC:6lectin, galactoside-binding, soluble, 3 binding protein [Source:HGNC Sleucine-rich repeat LGI family, member 4 [Source:HGNC Symbol;Acc:HGlipoma HMGIC fusion partner [Source:HGNC Symbol;Acc:HGNC:6586]lipoma HMGIC fusion partner-like 2 [Source:HGNC Symbol;Acc:HGNC:65leukemia inhibitory factor receptor alpha [Source:HGNC Symbol;Acc:HGleukocyte immunoglobulin-like receptor, subfamily A (with TM domainLIM domains containing 1 [Source:HGNC Symbol;Acc:HGNC:6612]LIM domain kinase 2 [Source:HGNC Symbol;Acc:HGNC:6614]lethal giant larvae homolog 1 (Drosophila) [Source:HGNC Symbol;Acc:Hlethal giant larvae homolog 2 (Drosophila) [Source:HGNC Symbol;Acc:Hlectin, mannose-binding, 1 [Source:HGNC Symbol;Acc:HGNC:6631]LIM and cysteine-rich domains 1 [Source:HGNC Symbol;Acc:HGNC:6633]lamin A/C [Source:HGNC Symbol;Acc:HGNC:6636]leiomodin 1 (smooth muscle) [Source:HGNC Symbol;Acc:HGNC:6647]leucyl/cystinyl aminopeptidase [Source:HGNC Symbol;Acc:HGNC:6656]lysyl oxidase-like 1 [Source:HGNC Symbol;Acc:HGNC:6665]lysyl oxidase-like 3 [Source:HGNC Symbol;Acc:HGNC:13869]LIM domain containing preferred translocation partner in lipoma [Souleupaxin [Source:HGNC Symbol;Acc:HGNC:14061]leucine-rich repeats and immunoglobulin-like domains 1 [Source:HGNCleucine-rich repeats and immunoglobulin-like domains 2 [Source:HGNCleucine-rich repeats and immunoglobulin-like domains 3 [Source:HGNClow density lipoprotein receptor-related protein 10 [Source:HGNC Sym

KRT8KRTCAP2KTN1LAMA1LAMA2LAMA4LAMA5LAMB2LAMC1LAMP1

LAPTM4ALAPTM4BLAPTM5LARSLATS1LATS2LBRLCATLDLRLEF1LEPRLFNGLGALS1LGALS3LGALS3BPLGI4LHFPLHFPL2LIFRLILRA2LIMD1LIMK2LLGL1LLGL2LMAN1LMCD1LMNALMOD1LNPEPLOXL1LOXL3LPPLPXNLRIG1LRIG2LRIG3LRP10
















































low density lipoprotein receptor-related protein 2 [Source:HGNC Symbolow density lipoprotein receptor-related protein 4 [Source:HGNC Symbolow density lipoprotein receptor-related protein 6 [Source:HGNC Symboleucine rich repeat (in FLII) interacting protein 2 [Source:HGNC Symbollanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) [Source:HGleukocyte specific transcript 1 [Source:HGNC Symbol;Acc:HGNC:14189]latent transforming growth factor beta binding protein 1 [Source:HGNlatent transforming growth factor beta binding protein 3 [Source:HGNlactotransferrin [Source:HGNC Symbol;Acc:HGNC:6720]LUC7-like (S. cerevisiae) [Source:HGNC Symbol;Acc:HGNC:6723]LYN proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;Alysophospholipase I [Source:HGNC Symbol;Acc:HGNC:6737]leucine zipper, putative tumor suppressor 2 [Source:HGNC Symbol;Acc:microtubule-actin crosslinking factor 1 [Source:HGNC Symbol;Acc:HGNCv-maf avian musculoaponeurotic fibrosarcoma oncogene homolog [SouMAF1 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:HGNC:24966]v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B [Sv-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F [Sv-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K [Smale germ cell-associated kinase [Source:HGNC Symbol;Acc:HGNC:6816]mastermind-like 2 (Drosophila) [Source:HGNC Symbol;Acc:HGNC:16259]mannosidase, alpha, class 2A, member 1 [Source:HGNC Symbol;Acc:HGNmannosidase, alpha, class 2B, member 1 [Source:HGNC Symbol;Acc:HGNmannosidase, beta A, lysosomal [Source:HGNC Symbol;Acc:HGNC:6831]

MAOB monoamine oxidase B [Source:HGNC Symbol;Acc:HGNC:6834]mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin proteinmitogen-activated protein kinase kinase kinase 11 [Source:HGNC Symbomitogen-activated protein kinase kinase kinase 2 [Source:HGNC Symbolmitogen-activated protein kinase kinase kinase 3 [Source:HGNC Symbolmitogen-activated protein kinase kinase kinase 8 [Source:HGNC Symbolmitogen-activated protein kinase kinase kinase kinase 4 [Source:HGNCmitogen-activated protein kinase kinase kinase kinase 5 [Source:HGNCmitogen-activated protein kinase-activated protein kinase 2 [Source:mitogen-activated protein kinase-activated protein kinase 3 [Source:microtubule-associated protein, RP/EB family, member 1 [Source:HGNCmyristoylated alanine-rich protein kinase C substrate [Source:HGNC SyMAP/microtubule affinity-regulating kinase 3 [Source:HGNC Symbol;Acmannan-binding lectin serine peptidase 1 (C4/C2 activating component methionine adenosyltransferase II, alpha [Source:HGNC Symbol;Acc:HGmatrilin 2 [Source:HGNC Symbol;Acc:HGNC:6908]MYC associated factor X [Source:HGNC Symbol;Acc:HGNC:6913]methyl-CpG binding domain protein 4 [Source:HGNC Symbol;Acc:HGNC:methyl-CpG binding domain protein 5 [Source:HGNC Symbol;Acc:HGNC:methyl-CpG binding domain protein 6 [Source:HGNC Symbol;Acc:HGNC:muscleblind-like splicing regulator 1 [Source:HGNC Symbol;Acc:HGNC:69myelin basic protein [Source:HGNC Symbol;Acc:HGNC:6925]mbt domain containing 1 [Source:HGNC Symbol;Acc:HGNC:19866]mutated in colorectal cancers [Source:HGNC Symbol;Acc:HGNC:6935]

LRP2LRP4LRP6LRRFIP2LSSLST1LTBP1LTBP3LTFLUC7LLYNLYPLA1LZTS2MACF1MAFMAF1MAFBMAFFMAFKMAKMAML2MAN2A1MAN2B1MANBA

MAP3K1MAP3K11MAP3K2MAP3K3MAP3K8MAP4K4MAP4K5MAPKAPK2MAPKAPK3MAPRE1MARCKSMARK3MASP1MAT2AMATN2MAXMBD4MBD5MBD6MBNL1MBPMBTD1MCC
















































myeloid cell leukemia 1 [Source:HGNC Symbol;Acc:HGNC:6943]minichromosome maintenance complex component 5 [Source:HGNC Syminichromosome maintenance complex component 7 [Source:HGNC Syminichromosome maintenance complex component 8 [Source:HGNC SyMdm1 nuclear protein homolog (mouse) [Source:HGNC Symbol;Acc:HGNMDM4, p53 regulator [Source:HGNC Symbol;Acc:HGNC:6974]multiple EGF-like-domains 10 [Source:HGNC Symbol;Acc:HGNC:29634]Meis homeobox 3 [Source:HGNC Symbol;Acc:HGNC:29537]mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltranmicrosomal glutathione S-transferase 1 [Source:HGNC Symbol;Acc:HGNCMHC class I polypeptide-related sequence A [Source:HGNC Symbol;Acc:microtubule associated monooxygenase, calponin and LIM domain cont

MID1 midline 1 [Source:HGNC Symbol;Acc:HGNC:7095]midnolin [Source:HGNC Symbol;Acc:HGNC:16298]muskelin 1, intracellular mediator containing kelch motifs [Source:HGMAP kinase interacting serine/threonine kinase 1 [Source:HGNC SymboMAP kinase interacting serine/threonine kinase 2 [Source:HGNC Symbomegalencephalic leukoencephalopathy with subcortical cysts 1 [SourcmutL homolog 3 [Source:HGNC Symbol;Acc:HGNC:7128]myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosopmalonyl-CoA decarboxylase [Source:HGNC Symbol;Acc:HGNC:7150]methylmalonic aciduria (cobalamin deficiency) cblB type [Source:HGNCmatrix metallopeptidase 2 [Source:HGNC Symbol;Acc:HGNC:7166]Mov10 RISC complex RNA helicase [Source:HGNC Symbol;Acc:HGNC:720multiple PDZ domain protein [Source:HGNC Symbol;Acc:HGNC:7208]mercaptopyruvate sulfurtransferase [Source:HGNC Symbol;Acc:HGNC:72myelin protein zero-like 1 [Source:HGNC Symbol;Acc:HGNC:7226]muscle RAS oncogene homolog [Source:HGNC Symbol;Acc:HGNC:7227]mannose receptor, C type 2 [Source:HGNC Symbol;Acc:HGNC:16875]MRE11 meiotic recombination 11 homolog A (S. cerevisiae) [Source:HGMAS-related GPR, member F [Source:HGNC Symbol;Acc:HGNC:24828]mitochondrial ribosomal protein L39 [Source:HGNC Symbol;Acc:HGNC:1mitochondrial ribosomal protein S14 [Source:HGNC Symbol;Acc:HGNC:1mitochondrial ribosomal protein S16 [Source:HGNC Symbol;Acc:HGNC:1mitochondrial ribosomal protein S5 [Source:HGNC Symbol;Acc:HGNC:14murine retrovirus integration site 1 homolog [Source:HGNC Symbol;Accmembrane-spanning 4-domains, subfamily A, member 6A [Source:HGNCmembrane-spanning 4-domains, subfamily A, member 7 [Source:HGNC mutS homolog 6 [Source:HGNC Symbol;Acc:HGNC:7329]musashi RNA-binding protein 2 [Source:HGNC Symbol;Acc:HGNC:18585]

MSN moesin [Source:HGNC Symbol;Acc:HGNC:7373]macrophage stimulating 1 [Source:HGNC Symbol;Acc:HGNC:7380]msh homeobox 1 [Source:HGNC Symbol;Acc:HGNC:7391]metallothionein 1E [Source:HGNC Symbol;Acc:HGNC:7397]metallothionein 1F [Source:HGNC Symbol;Acc:HGNC:7398]metallothionein 1G [Source:HGNC Symbol;Acc:HGNC:7399]metallothionein 1H [Source:HGNC Symbol;Acc:HGNC:7400]metallothionein 1X [Source:HGNC Symbol;Acc:HGNC:7405]

MCL1MCM5MCM7MCM8MDM1MDM4MEGF10MEIS3MGAT1MGST1MICAMICAL3

MIDNMKLN1MKNK1MKNK2MLC1MLH3MLLT4MLYCDMMABMMP2MOV10MPDZMPSTMPZL1MRASMRC2MRE11AMRGPRFMRPL39MRPS14MRPS16MRPS5MRVI1MS4A6AMS4A7MSH6MSI2

MST1MSX1MT1EMT1FMT1GMT1HMT1X















































metallothionein 2A [Source:HGNC Symbol;Acc:HGNC:7406]metallothionein 3 [Source:HGNC Symbol;Acc:HGNC:7408]metal-regulatory transcription factor 1 [Source:HGNC Symbol;Acc:HGNC

MTM1 myotubularin 1 [Source:HGNC Symbol;Acc:HGNC:7448]myotubularin related protein 3 [Source:HGNC Symbol;Acc:HGNC:7451]myotubularin related protein 9 [Source:HGNC Symbol;Acc:HGNC:14596]mitochondrial translational release factor 1-like [Source:HGNC Symbolmucin 4, cell surface associated [Source:HGNC Symbol;Acc:HGNC:7514]melanoma associated antigen (mutated) 1 [Source:HGNC Symbol;Acc:HMUS81 structure-specific endonuclease subunit [Source:HGNC Symbol;methylmalonyl CoA mutase [Source:HGNC Symbol;Acc:HGNC:7526]mutY homolog [Source:HGNC Symbol;Acc:HGNC:7527]mevalonate kinase [Source:HGNC Symbol;Acc:HGNC:7530]major vault protein [Source:HGNC Symbol;Acc:HGNC:7531]MAX dimerization protein 4 [Source:HGNC Symbol;Acc:HGNC:13906]MAX interactor 1, dimerization protein [Source:HGNC Symbol;Acc:HGNCv-myb avian myeloblastosis viral oncogene homolog-like 1 [Source:HGmyosin binding protein C, slow type [Source:HGNC Symbol;Acc:HGNC:75myosin, heavy chain 7B, cardiac muscle, beta [Source:HGNC Symbol;Acmyosin, light chain 6, alkali, smooth muscle and non-muscle [Source:myosin regulatory light chain interacting protein [Source:HGNC Symbolmyosin light chain kinase [Source:HGNC Symbol;Acc:HGNC:7590]myosin X [Source:HGNC Symbol;Acc:HGNC:7593]myosin IC [Source:HGNC Symbol;Acc:HGNC:7597]myosin IE [Source:HGNC Symbol;Acc:HGNC:7599]myosin IF [Source:HGNC Symbol;Acc:HGNC:7600]myosin VI [Source:HGNC Symbol;Acc:HGNC:7605]myosin IXB [Source:HGNC Symbol;Acc:HGNC:7609]myomesin 1 [Source:HGNC Symbol;Acc:HGNC:7613]myosin VIIA and Rab interacting protein [Source:HGNC Symbol;Acc:HGNNEDD4 binding protein 1 [Source:HGNC Symbol;Acc:HGNC:29850]NGFI-A binding protein 1 (EGR1 binding protein 1) [Source:HGNC Symbonascent polypeptide-associated complex alpha subunit [Source:HGNC SN-acetylglucosamine kinase [Source:HGNC Symbol;Acc:HGNC:17174]nuclear autoantigenic sperm protein (histone-binding) [Source:HGNC Sneuron navigator 1 [Source:HGNC Symbol;Acc:HGNC:15989]neuron navigator 2 [Source:HGNC Symbol;Acc:HGNC:15997]NCK adaptor protein 1 [Source:HGNC Symbol;Acc:HGNC:7664]nuclear receptor coactivator 3 [Source:HGNC Symbol;Acc:HGNC:7670]nuclear receptor coactivator 6 [Source:HGNC Symbol;Acc:HGNC:15936]nuclear receptor corepressor 2 [Source:HGNC Symbol;Acc:HGNC:7673]nicastrin [Source:HGNC Symbol;Acc:HGNC:17091]nudE neurodevelopment protein 1 [Source:HGNC Symbol;Acc:HGNC:176N-myc downstream regulated 1 [Source:HGNC Symbol;Acc:HGNC:7679]NDRG family member 2 [Source:HGNC Symbol;Acc:HGNC:14460]nebulette [Source:HGNC Symbol;Acc:HGNC:16932]neural precursor cell expressed, developmentally down-regulated 1 [NIMA-related kinase 1 [Source:HGNC Symbol;Acc:HGNC:7744]

MT2AMT3MTF1

MTMR3MTMR9MTRF1LMUC4MUM1MUS81MUTMUTYHMVKMVPMXD4MXI1MYBL1MYBPC1MYH7BMYL6MYLIPMYLKMYO10MYO1CMYO1EMYO1FMYO6MYO9BMYOM1MYRIPN4BP1NAB1NACANAGKNASPNAV1NAV2NCK1NCOA3NCOA6NCOR2NCSTNNDE1NDRG1NDRG2NEBLNEDD1NEK1
















































NIMA-related kinase 11 [Source:HGNC Symbol;Acc:HGNC:18593]NIMA-related kinase 3 [Source:HGNC Symbol;Acc:HGNC:7746]NIMA-related kinase 4 [Source:HGNC Symbol;Acc:HGNC:11399]NIMA-related kinase 7 [Source:HGNC Symbol;Acc:HGNC:13386]NIMA-related kinase 9 [Source:HGNC Symbol;Acc:HGNC:18591]neogenin 1 [Source:HGNC Symbol;Acc:HGNC:7754]neuroepithelial cell transforming 1 [Source:HGNC Symbol;Acc:HGNC:145neurofascin [Source:HGNC Symbol;Acc:HGNC:29866]nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependennuclear factor of activated T-cells, cytoplasmic, calcineurin-dependennuclear factor, erythroid 2-like 1 [Source:HGNC Symbol;Acc:HGNC:7781]nuclear factor, erythroid 2-like 2 [Source:HGNC Symbol;Acc:HGNC:7782]nuclear factor I/A [Source:HGNC Symbol;Acc:HGNC:7784]nuclear factor I/B [Source:HGNC Symbol;Acc:HGNC:7785]nuclear factor I/C (CCAAT-binding transcription factor) [Source:HGNC nuclear factor I/X (CCAAT-binding transcription factor) [Source:HGNC nuclear factor of kappa light polypeptide gene enhancer in B-cells inhnuclear factor of kappa light polypeptide gene enhancer in B-cells inhnuclear factor of kappa light polypeptide gene enhancer in B-cells inhinuclear transcription factor Y, alpha [Source:HGNC Symbol;Acc:HGNC:78nescient helix loop helix 2 [Source:HGNC Symbol;Acc:HGNC:7818]ninein (GSK3B interacting protein) [Source:HGNC Symbol;Acc:HGNC:149ninjurin 1 [Source:HGNC Symbol;Acc:HGNC:7824]nitrilase 1 [Source:HGNC Symbol;Acc:HGNC:7828]natural killer cell triggering receptor [Source:HGNC Symbol;Acc:HGNC:78NK3 homeobox 1 [Source:HGNC Symbol;Acc:HGNC:7838]neurolysin (metallopeptidase M3 family) [Source:HGNC Symbol;Acc:HGNneuromedin B [Source:HGNC Symbol;Acc:HGNC:7842]NME/NM23 nucleoside diphosphate kinase 3 [Source:HGNC Symbol;AccN-myc (and STAT) interactor [Source:HGNC Symbol;Acc:HGNC:7854]N-myristoyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:7857]nicotinamide N-methyltransferase [Source:HGNC Symbol;Acc:HGNC:786nucleolar protein 3 (apoptosis repressor with CARD domain) [Source:notch 1 [Source:HGNC Symbol;Acc:HGNC:7881]notch 2 [Source:HGNC Symbol;Acc:HGNC:7882]notch 3 [Source:HGNC Symbol;Acc:HGNC:7883]neuronal PAS domain protein 3 [Source:HGNC Symbol;Acc:HGNC:19311]Niemann-Pick disease, type C1 [Source:HGNC Symbol;Acc:HGNC:7897]Niemann-Pick disease, type C2 [Source:HGNC Symbol;Acc:HGNC:14537]aminopeptidase puromycin sensitive [Source:HGNC Symbol;Acc:HGNC:7neuropeptide FF-amide peptide precursor [Source:HGNC Symbol;Acc:Hnephronophthisis 3 (adolescent) [Source:HGNC Symbol;Acc:HGNC:7907]N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) [Snuclear receptor subfamily 1, group D, member 2 [Source:HGNC Symbolnuclear receptor subfamily 1, group H, member 3 [Source:HGNC Symbolnuclear receptor subfamily 2, group F, member 1 [Source:HGNC Symbolnuclear receptor subfamily 2, group F, member 2 [Source:HGNC Symbolnuclear receptor subfamily 3, group C, member 1 (glucocorticoid rece

NEK11NEK3NEK4NEK7NEK9NEO1NET1NFASCNFATC1NFATC3NFE2L1NFE2L2NFIANFIBNFICNFIXNFKBIANFKBIBNFKBIENFYANHLH2NINNINJ1NIT1NKTRNKX3-1NLNNMBNME3NMINMT1NNMTNOL3NOTCH1NOTCH2NOTCH3NPAS3NPC1NPC2NPEPPSNPFFNPHP3NPLNR1D2NR1H3NR2F1NR2F2NR3C1

















































nardilysin (N-arginine dibasic convertase) [Source:HGNC Symbol;Acc:HGnuclear receptor binding SET domain protein 1 [Source:HGNC Symbol;A5'-nucleotidase, cytosolic II [Source:HGNC Symbol;Acc:HGNC:8022]nudix (nucleoside diphosphate linked moiety X)-type motif 12 [Sourcenudix (nucleoside diphosphate linked moiety X)-type motif 5 [Source:nuclear mitotic apparatus protein 1 [Source:HGNC Symbol;Acc:HGNC:80numb homolog (Drosophila) [Source:HGNC Symbol;Acc:HGNC:8060]nucleoporin 153kDa [Source:HGNC Symbol;Acc:HGNC:8062]nucleoporin 160kDa [Source:HGNC Symbol;Acc:HGNC:18017]nucleoporin 214kDa [Source:HGNC Symbol;Acc:HGNC:8064]nucleoporin 43kDa [Source:HGNC Symbol;Acc:HGNC:21182]nucleoporin 54kDa [Source:HGNC Symbol;Acc:HGNC:17359]nucleoporin 62kDa [Source:HGNC Symbol;Acc:HGNC:8066]nucleoporin 88kDa [Source:HGNC Symbol;Acc:HGNC:8067]nucleoporin 98kDa [Source:HGNC Symbol;Acc:HGNC:8068]nucleoredoxin [Source:HGNC Symbol;Acc:HGNC:18008]

NXT2 nuclear transport factor 2-like export factor 2 [Source:HGNC Symbol;Aornithine decarboxylase 1 [Source:HGNC Symbol;Acc:HGNC:8109]

OFD1 oral-facial-digital syndrome 1 [Source:HGNC Symbol;Acc:HGNC:2567]oligodendrocyte lineage transcription factor 2 [Source:HGNC Symbol;Aoxysterol binding protein-like 11 [Source:HGNC Symbol;Acc:HGNC:16397oxysterol binding protein-like 1A [Source:HGNC Symbol;Acc:HGNC:16398oxysterol binding protein-like 3 [Source:HGNC Symbol;Acc:HGNC:16370]oxysterol binding protein-like 7 [Source:HGNC Symbol;Acc:HGNC:16387]O-sialoglycoprotein endopeptidase-like 1 [Source:HGNC Symbol;Acc:HGodd-skipped related transciption factor 1 [Source:HGNC Symbol;Acc:HGotospiralin [Source:HGNC Symbol;Acc:HGNC:22644]purinergic receptor P2X, ligand gated ion channel, 7 [Source:HGNC Symprolyl 4-hydroxylase, alpha polypeptide II [Source:HGNC Symbol;Acc:HGprolyl 4-hydroxylase, beta polypeptide [Source:HGNC Symbol;Acc:HGNC:poly(A) binding protein, cytoplasmic 3 [Source:HGNC Symbol;Acc:HGNC:poly(A) binding protein, nuclear 1 [Source:HGNC Symbol;Acc:HGNC:8565protein kinase C and casein kinase substrate in neurons 2 [Source:HGNprotein kinase C and casein kinase substrate in neurons 3 [Source:HGNpeptidyl arginine deiminase, type II [Source:HGNC Symbol;Acc:HGNC:18phenylalanine hydroxylase [Source:HGNC Symbol;Acc:HGNC:8582]phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidap21 protein (Cdc42/Rac)-activated kinase 2 [Source:HGNC Symbol;Acc:PAN3 poly(A) specific ribonuclease subunit [Source:HGNC Symbol;Acc:pantothenate kinase 2 [Source:HGNC Symbol;Acc:HGNC:15894]papilin, proteoglycan-like sulfated glycoprotein [Source:HGNC Symbol;poly(A) polymerase alpha [Source:HGNC Symbol;Acc:HGNC:14981]3'-phosphoadenosine 5'-phosphosulfate synthase 2 [Source:HGNC Symbpar-3 family cell polarity regulator [Source:HGNC Symbol;Acc:HGNC:160PRKC, apoptosis, WT1, regulator [Source:HGNC Symbol;Acc:HGNC:8614]paired box 6 [Source:HGNC Symbol;Acc:HGNC:8620]pre-B-cell leukemia homeobox 4 [Source:HGNC Symbol;Acc:HGNC:13403poly(rC) binding protein 2 [Source:HGNC Symbol;Acc:HGNC:8648]

NRD1NSD1NT5C2NUDT12NUDT5NUMA1NUMBNUP153NUP160NUP214NUP43NUP54NUP62NUP88NUP98NXN

ODC1

OLIG2OSBPL11OSBPL1AOSBPL3OSBPL7OSGEPL1OSR1OTOSP2RX7P4HA2P4HBPABPC3PABPN1PACSIN2PACSIN3PADI2PAHPAICSPAK2PAN3PANK2PAPLNPAPOLAPAPSS2PARD3PAWRPAX6PBX4PCBP2















































poly(rC) binding protein 4 [Source:HGNC Symbol;Acc:HGNC:8652]protocadherin 18 [Source:HGNC Symbol;Acc:HGNC:14268]protocadherin 9 [Source:HGNC Symbol;Acc:HGNC:8661]protocadherin gamma subfamily A, 8 [Source:HGNC Symbol;Acc:HGNC:8PCF11 cleavage and polyadenylation factor subunit [Source:HGNC Symbphosphoenolpyruvate carboxykinase 2 (mitochondrial) [Source:HGNC Sproprotein convertase subtilisin/kexin type 5 [Source:HGNC Symbol;Acprogrammed cell death 4 (neoplastic transformation inhibitor) [Sourcprogrammed cell death 6 [Source:HGNC Symbol;Acc:HGNC:8765]programmed cell death 7 [Source:HGNC Symbol;Acc:HGNC:8767]phosducin-like [Source:HGNC Symbol;Acc:HGNC:8770]phosducin-like 2 [Source:HGNC Symbol;Acc:HGNC:29524]phosphodiesterase 4C, cAMP-specific [Source:HGNC Symbol;Acc:HGNC:8phosphodiesterase 4D interacting protein [Source:HGNC Symbol;Acc:HGphosphodiesterase 7A [Source:HGNC Symbol;Acc:HGNC:8791]platelet-derived growth factor alpha polypeptide [Source:HGNC Symbolplatelet derived growth factor C [Source:HGNC Symbol;Acc:HGNC:8801]platelet-derived growth factor receptor, beta polypeptide [Source:HGpyruvate dehydrogenase kinase, isozyme 4 [Source:HGNC Symbol;Acc:HPDZ and LIM domain 1 [Source:HGNC Symbol;Acc:HGNC:2067]PDZ and LIM domain 2 (mystique) [Source:HGNC Symbol;Acc:HGNC:1399phosphoprotein enriched in astrocytes 15 [Source:HGNC Symbol;Acc:HGplatelet/endothelial cell adhesion molecule 1 [Source:HGNC Symbol;Acperoxisomal trans-2-enoyl-CoA reductase [Source:HGNC Symbol;Acc:HGpellino E3 ubiquitin protein ligase family member 2 [Source:HGNC Symbpeptidase D [Source:HGNC Symbol;Acc:HGNC:8840]period circadian clock 1 [Source:HGNC Symbol;Acc:HGNC:8845]peroxisomal biogenesis factor 1 [Source:HGNC Symbol;Acc:HGNC:8850]peroxisomal biogenesis factor 10 [Source:HGNC Symbol;Acc:HGNC:8851]peroxisomal biogenesis factor 11 alpha [Source:HGNC Symbol;Acc:HGNC6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 [Source:HGNC6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 [Source:HGNC6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 [Source:HGNCphosphoglycerate mutase 2 (muscle) [Source:HGNC Symbol;Acc:HGNC:8protein geranylgeranyltransferase type I, beta subunit [Source:HGNC S6-phosphogluconolactonase [Source:HGNC Symbol;Acc:HGNC:8903]phosphoglucomutase 1 [Source:HGNC Symbol;Acc:HGNC:8905]phosphoglucomutase 2 [Source:HGNC Symbol;Acc:HGNC:8906]phosphatidylglycerophosphate synthase 1 [Source:HGNC Symbol;Acc:Hphosphatase and actin regulator 3 [Source:HGNC Symbol;Acc:HGNC:158phosphatase and actin regulator 4 [Source:HGNC Symbol;Acc:HGNC:257prohibitin [Source:HGNC Symbol;Acc:HGNC:8912]polyhomeotic homolog 1 (Drosophila) [Source:HGNC Symbol;Acc:HGNC:polyhomeotic homolog 3 (Drosophila) [Source:HGNC Symbol;Acc:HGNC:PHD finger protein 10 [Source:HGNC Symbol;Acc:HGNC:18250]PHD finger protein 12 [Source:HGNC Symbol;Acc:HGNC:20816]PHD finger protein 13 [Source:HGNC Symbol;Acc:HGNC:22983]PHD finger protein 19 [Source:HGNC Symbol;Acc:HGNC:24566]

PCBP4PCDH18PCDH9PCDHGA8PCF11PCK2PCSK5PDCD4PDCD6PDCD7PDCLPDCL2PDE4CPDE4DIPPDE7APDGFAPDGFCPDGFRBPDK4PDLIM1PDLIM2PEA15PECAM1PECRPELI2PEPDPER1PEX1PEX10PEX11APFKFB2PFKFB3PFKFB4PGAM2PGGT1BPGLSPGM1PGM2PGS1PHACTR3PHACTR4PHBPHC1PHC3PHF10PHF12PHF13PHF19

















































PHD finger protein 2 [Source:HGNC Symbol;Acc:HGNC:8920]PHD finger protein 3 [Source:HGNC Symbol;Acc:HGNC:8921]phosphoglycerate dehydrogenase [Source:HGNC Symbol;Acc:HGNC:8923pleckstrin homology domain interacting protein [Source:HGNC Symbol;phosphorylase kinase, gamma 1 (muscle) [Source:HGNC Symbol;Acc:HGpleckstrin homology-like domain, family A, member 3 [Source:HGNC Syphytanoyl-CoA dioxygenase domain containing 1 [Source:HGNC Symbolprotein inhibitor of activated STAT, 3 [Source:HGNC Symbol;Acc:HGNC:1phosphatidylinositol binding clathrin assembly protein [Source:HGNC

PIGA phosphatidylinositol glycan anchor biosynthesis, class A [Source:HGNCphosphatidylinositol glycan anchor biosynthesis, class M [Source:HGNphosphatidylinositol 3-kinase, catalytic subunit type 3 [Source:HGNC Sphosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit deltphosphoinositide-3-kinase, regulatory subunit 1 (alpha) [Source:HGNCPim-1 proto-oncogene, serine/threonine kinase [Source:HGNC Symbol;polycystic kidney disease 2 (autosomal dominant) [Source:HGNC Symboprotein kinase N3 [Source:HGNC Symbol;Acc:HGNC:17999]phospholipase A1 member A [Source:HGNC Symbol;Acc:HGNC:17661]placenta-specific 9 [Source:HGNC Symbol;Acc:HGNC:19255]pleiomorphic adenoma gene 1 [Source:HGNC Symbol;Acc:HGNC:9045]phospholipase C, delta 1 [Source:HGNC Symbol;Acc:HGNC:9060]phospholipase C, epsilon 1 [Source:HGNC Symbol;Acc:HGNC:17175]phospholipase D1, phosphatidylcholine-specific [Source:HGNC Symbol;pleckstrin homology domain containing, family B (evectins) member 1pleckstrin homology domain containing, family G (with RhoGef domaipleckstrin homology domain containing, family H (with MyTH4 domainprocollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 [Source:HGNC Symbprocollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 [Source:HGNC Symb

PLP2 proteolipid protein 2 (colonic epithelium-enriched) [Source:HGNC SymbPLS3 plastin 3 [Source:HGNC Symbol;Acc:HGNC:9091]

phospholipid scramblase 1 [Source:HGNC Symbol;Acc:HGNC:9092]phospholipid scramblase 4 [Source:HGNC Symbol;Acc:HGNC:16497]phospholipid transfer protein [Source:HGNC Symbol;Acc:HGNC:9093]plexin domain containing 2 [Source:HGNC Symbol;Acc:HGNC:21013]plexin B1 [Source:HGNC Symbol;Acc:HGNC:9103]plexin B2 [Source:HGNC Symbol;Acc:HGNC:9104]

PLXNB3 plexin B3 [Source:HGNC Symbol;Acc:HGNC:9105]pro-melanin-concentrating hormone [Source:HGNC Symbol;Acc:HGNC:9peripheral myelin protein 2 [Source:HGNC Symbol;Acc:HGNC:9117]phosphomevalonate kinase [Source:HGNC Symbol;Acc:HGNC:9141]pinin, desmosome associated protein [Source:HGNC Symbol;Acc:HGNC:9podocalyxin-like [Source:HGNC Symbol;Acc:HGNC:9171]pogo transposable element with KRAB domain [Source:HGNC Symbol;Apogo transposable element with ZNF domain [Source:HGNC Symbol;Accpolymerase (DNA-directed), delta 3, accessory subunit [Source:HGNC Spolymerase (DNA directed) iota [Source:HGNC Symbol;Acc:HGNC:9182]polymerase (RNA) II (DNA directed) polypeptide G [Source:HGNC Symbopolymerase (RNA) II (DNA directed) polypeptide H [Source:HGNC Symbo

PHF2PHF3PHGDHPHIPPHKG1PHLDA3PHYHD1PIAS3PICALM

PIGMPIK3C3PIK3CDPIK3R1PIM1PKD2PKN3PLA1APLAC9PLAG1PLCD1PLCE1PLD1PLEKHB1PLEKHG1PLEKHH1PLOD2PLOD3

PLSCR1PLSCR4PLTPPLXDC2PLXNB1PLXNB2

PMCHPMP2PMVKPNNPODXLPOGKPOGZPOLD3POLIPOLR2GPOLR2H













































polymerase (RNA) III (DNA directed) polypeptide E (80kD) [Source:HGNprotein-O-mannosyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:1974paraoxonase 2 [Source:HGNC Symbol;Acc:HGNC:9205]processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae)POU class 2 associating factor 1 [Source:HGNC Symbol;Acc:HGNC:9211]POU class 2 homeobox 1 [Source:HGNC Symbol;Acc:HGNC:9212]POU class 3 homeobox 2 [Source:HGNC Symbol;Acc:HGNC:9215]POU class 3 homeobox 3 [Source:HGNC Symbol;Acc:HGNC:9216]POU class 4 homeobox 1 [Source:HGNC Symbol;Acc:HGNC:9218]POU class 4 homeobox 2 [Source:HGNC Symbol;Acc:HGNC:9219]phosphatidic acid phosphatase type 2A [Source:HGNC Symbol;Acc:HGNCphosphatidic acid phosphatase type 2B [Source:HGNC Symbol;Acc:HGNCperoxisome proliferator-activated receptor alpha [Source:HGNC Symbolprotein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), intPTPRF interacting protein, binding protein 1 (liprin beta 1) [Source:HPTPRF interacting protein, binding protein 2 (liprin beta 2) [Source:Hpeptidylprolyl isomerase B (cyclophilin B) [Source:HGNC Symbol;Acc:HGpeptidylprolyl isomerase C (cyclophilin C) [Source:HGNC Symbol;Acc:HGpeptidylprolyl isomerase F [Source:HGNC Symbol;Acc:HGNC:9259]peptidylprolyl isomerase G (cyclophilin G) [Source:HGNC Symbol;Acc:Hpeptidylprolyl isomerase (cyclophilin)-like 2 [Source:HGNC Symbol;Acc:protein phosphatase, Mg2+/Mn2+ dependent, 1F [Source:HGNC Symbolprotoporphyrinogen oxidase [Source:HGNC Symbol;Acc:HGNC:9280]protein phosphatase 1, regulatory (inhibitor) subunit 14B [Source:HGNprotein phosphatase 1, regulatory subunit 3D [Source:HGNC Symbol;Acprotein phosphatase 2, regulatory subunit A, beta [Source:HGNC Symboprotein phosphatase 2, regulatory subunit B', gamma [Source:HGNC Syprotein phosphatase 3, catalytic subunit, gamma isozyme [Source:HGNprotein phosphatase 4, catalytic subunit [Source:HGNC Symbol;Acc:HGNprotein phosphatase 4, regulatory subunit 1 [Source:HGNC Symbol;Accprotein phosphatase 4, regulatory subunit 2 [Source:HGNC Symbol;Accprolylcarboxypeptidase (angiotensinase C) [Source:HGNC Symbol;Acc:HPR domain containing 15 [Source:HGNC Symbol;Acc:HGNC:13999]PR domain containing 16 [Source:HGNC Symbol;Acc:HGNC:14000]peroxiredoxin 1 [Source:HGNC Symbol;Acc:HGNC:9352]proline/arginine-rich end leucine-rich repeat protein [Source:HGNC Syphosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange facprotein kinase, AMP-activated, beta 1 non-catalytic subunit [Source:Hprotein kinase, cAMP-dependent, regulatory, type I, alpha [Source:HGprotein kinase, cAMP-dependent, regulatory, type II, alpha [Source:Hprotein kinase D2 [Source:HGNC Symbol;Acc:HGNC:17293]protein kinase, interferon-inducible double stranded RNA dependent a

PRKX protein kinase, X-linked [Source:HGNC Symbol;Acc:HGNC:9441]proline dehydrogenase (oxidase) 1 [Source:HGNC Symbol;Acc:HGNC:945protein S (alpha) [Source:HGNC Symbol;Acc:HGNC:9456]pre-mRNA processing factor 31 [Source:HGNC Symbol;Acc:HGNC:15446]paired related homeobox 1 [Source:HGNC Symbol;Acc:HGNC:9142]phosphoserine aminotransferase 1 [Source:HGNC Symbol;Acc:HGNC:191

POLR3EPOMT2PON2POP5POU2AF1POU2F1POU3F2POU3F3POU4F1POU4F2PPAP2APPAP2BPPARAPPFIA1PPFIBP1PPFIBP2PPIBPPICPPIFPPIGPPIL2PPM1FPPOXPPP1R14BPPP1R3DPPP2R1BPPP2R5CPPP3CCPPP4CPPP4R1PPP4R2PRCPPRDM15PRDM16PRDX1PRELPPREX1PRKAB1PRKAR1APRKAR2APRKD2PRKRA

PRODHPROS1PRPF31PRRX1PSAT1
















































proteasome (prosome, macropain) subunit, alpha type, 3 [Source:HGNCproteasome (prosome, macropain) subunit, beta type, 8 [Source:HGNCproteasome (prosome, macropain) subunit, beta type, 9 [Source:HGNCproteasome (prosome, macropain) 26S subunit, non-ATPase, 9 [Sourceproteasome (prosome, macropain) activator subunit 2 (PA28 beta) [Soproteasome (prosome, macropain) activator subunit 4 [Source:HGNC Sphosphoserine phosphatase [Source:HGNC Symbol;Acc:HGNC:9577]protein prenyltransferase alpha subunit repeat containing 1 [Source:polypyrimidine tract binding protein 1 [Source:HGNC Symbol;Acc:HGNC:pentatricopeptide repeat domain 1 [Source:HGNC Symbol;Acc:HGNC:22phosphatidylserine synthase 2 [Source:HGNC Symbol;Acc:HGNC:15463]phosphotriesterase related [Source:HGNC Symbol;Acc:HGNC:9590]prostaglandin D2 synthase 21kDa (brain) [Source:HGNC Symbol;Acc:HGNprotein tyrosine kinase 2 [Source:HGNC Symbol;Acc:HGNC:9611]prothymosin, alpha [Source:HGNC Symbol;Acc:HGNC:9623]protein tyrosine phosphatase type IVA, member 2 [Source:HGNC Symboprotein tyrosine phosphatase, non-receptor type 12 [Source:HGNC Symprotein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fasprotein tyrosine phosphatase, non-receptor type 2 [Source:HGNC Symbprotein tyrosine phosphatase, non-receptor type 21 [Source:HGNC Symprotein tyrosine phosphatase, receptor type, A [Source:HGNC Symbol;Aprotein tyrosine phosphatase, receptor type, C [Source:HGNC Symbol;Aprotein tyrosine phosphatase, receptor type, F [Source:HGNC Symbol;Aprotein tyrosine phosphatase, receptor type, K [Source:HGNC Symbol;Aprotein tyrosine phosphatase, receptor-type, Z polypeptide 1 [Sourcepolymerase I and transcript release factor [Source:HGNC Symbol;Acc:Hpituitary tumor-transforming 1 interacting protein [Source:HGNC Symbpurine-rich element binding protein A [Source:HGNC Symbol;Acc:HGNC:paxillin [Source:HGNC Symbol;Acc:HGNC:9718]pyrroline-5-carboxylate reductase family, member 2 [Source:HGNC Symphosphorylase, glycogen; brain [Source:HGNC Symbol;Acc:HGNC:9723]glutaminyl-tRNA synthetase [Source:HGNC Symbol;Acc:HGNC:9751]QKI, KH domain containing, RNA binding [Source:HGNC Symbol;Acc:HGNquinolinate phosphoribosyltransferase [Source:HGNC Symbol;Acc:HGNCRAB10, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:RAB13, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:RAB14, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:RAB23, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:RAB27A, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNCRAB28, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:RAB30, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:RAB31, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:RAB33B, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNCRAB34, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:RAB4A, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:RAB5B, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:rabaptin, RAB GTPase binding effector protein 1 [Source:HGNC Symbol;RAD51 recombinase [Source:HGNC Symbol;Acc:HGNC:9817]

PSMA3PSMB8PSMB9PSMD9PSME2PSME4PSPHPTAR1PTBP1PTCD1PTDSS2PTERPTGDSPTK2PTMAPTP4A2PTPN12PTPN13PTPN2PTPN21PTPRAPTPRCPTPRFPTPRKPTPRZ1PTRFPTTG1IPPURAPXNPYCR2PYGBQARSQKIQPRTRAB10RAB13RAB14RAB23RAB27ARAB28RAB30RAB31RAB33BRAB34RAB4ARAB5BRABEP1RAD51

















































RAD52 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:HGNC:9824]Raf-1 proto-oncogene, serine/threonine kinase [Source:HGNC Symbol;Aretinoic acid induced 14 [Source:HGNC Symbol;Acc:HGNC:14873]ralA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:9841]ral guanine nucleotide dissociation stimulator [Source:HGNC Symbol;AcRALY heterogeneous nuclear ribonucleoprotein [Source:HGNC Symbol;receptor (G protein-coupled) activity modifying protein 1 [Source:HGNreceptor (G protein-coupled) activity modifying protein 2 [Source:HGNreceptor (G protein-coupled) activity modifying protein 3 [Source:HGNRAP1A, member of RAS oncogene family [Source:HGNC Symbol;Acc:HGNRAP1B, member of RAS oncogene family [Source:HGNC Symbol;Acc:HGNRap guanine nucleotide exchange factor (GEF) 2 [Source:HGNC Symbol;Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 [Soretinoic acid receptor responder (tazarotene induced) 2 [Source:HGNCretinoic acid receptor responder (tazarotene induced) 3 [Source:HGNCRAS p21 protein activator (GTPase activating protein) 1 [Source:HGNC RAS p21 protein activator 2 [Source:HGNC Symbol;Acc:HGNC:9872]RAS p21 protein activator 3 [Source:HGNC Symbol;Acc:HGNC:20331]Ras association (RalGDS/AF-6) domain family member 4 [Source:HGNC ribonucleoprotein, PTB-binding 1 [Source:HGNC Symbol;Acc:HGNC:3029retinoblastoma binding protein 8 [Source:HGNC Symbol;Acc:HGNC:9891]retinoblastoma-like 2 [Source:HGNC Symbol;Acc:HGNC:9894]RNA binding motif protein 14 [Source:HGNC Symbol;Acc:HGNC:14219]RNA binding motif protein 15 [Source:HGNC Symbol;Acc:HGNC:14959]RNA binding motif protein 17 [Source:HGNC Symbol;Acc:HGNC:16944]RNA binding motif protein 5 [Source:HGNC Symbol;Acc:HGNC:9902]RNA binding motif protein 6 [Source:HGNC Symbol;Acc:HGNC:9903]RNA binding motif, single stranded interacting protein 2 [Source:HGNCRNA binding protein with multiple splicing [Source:HGNC Symbol;Acc:Hretinol dehydrogenase 5 (11-cis/9-cis) [Source:HGNC Symbol;Acc:HGNC:radixin [Source:HGNC Symbol;Acc:HGNC:9944]RecQ protein-like 5 [Source:HGNC Symbol;Acc:HGNC:9950]v-rel avian reticuloendotheliosis viral oncogene homolog A [Source:HREV3-like, polymerase (DNA directed), zeta, catalytic subunit [Sourcereplication factor C (activator 1) 1, 145kDa [Source:HGNC Symbol;Acc:Hreplication factor C (activator 1) 5, 36.5kDa [Source:HGNC Symbol;Acc:regulatory factor X, 2 (influences HLA class II expression) [Source:HGNregulatory factor X, 3 (influences HLA class II expression) [Source:HGNregulatory factor X, 4 (influences HLA class II expression) [Source:HGNregulatory factor X-associated ankyrin-containing protein [Source:HGNral guanine nucleotide dissociation stimulator-like 3 [Source:HGNC Symrepulsive guidance molecule family member a [Source:HGNC Symbol;Acretinal G protein coupled receptor [Source:HGNC Symbol;Acc:HGNC:999regulator of G-protein signaling 10 [Source:HGNC Symbol;Acc:HGNC:999regulator of G-protein signaling 3 [Source:HGNC Symbol;Acc:HGNC:9999Rho-related BTB domain containing 1 [Source:HGNC Symbol;Acc:HGNC:1Rho-related BTB domain containing 3 [Source:HGNC Symbol;Acc:HGNC:1ras homolog family member Q [Source:HGNC Symbol;Acc:HGNC:17736]

RAD52RAF1RAI14RALBP1RALGDSRALYRAMP1RAMP2RAMP3RAP1ARAP1BRAPGEF2RAPH1RARRES2RARRES3RASA1RASA2RASA3RASSF4RAVER1RBBP8RBL2RBM14RBM15RBM17RBM5RBM6RBMS2RBPMSRDH5RDXRECQL5RELAREV3LRFC1RFC5RFX2RFX3RFX4RFXANKRGL3RGMARGRRGS10RGS3RHOBTB1RHOBTB3RHOQ

















































rhophilin, Rho GTPase binding protein 1 [Source:HGNC Symbol;Acc:HGNRas and Rab interactor 2 [Source:HGNC Symbol;Acc:HGNC:18750]Ras and Rab interactor 3 [Source:HGNC Symbol;Acc:HGNC:18751]ribonuclease, RNase A family, 4 [Source:HGNC Symbol;Acc:HGNC:10047]ring finger protein 135 [Source:HGNC Symbol;Acc:HGNC:21158]ring finger protein 149 [Source:HGNC Symbol;Acc:HGNC:23137]ring finger protein 20, E3 ubiquitin protein ligase [Source:HGNC Symboring finger protein 24 [Source:HGNC Symbol;Acc:HGNC:13779]RNA guanylyltransferase and 5'-phosphatase [Source:HGNC Symbol;Accarginyl aminopeptidase (aminopeptidase B) [Source:HGNC Symbol;Acc:roundabout, axon guidance receptor, homolog 4 (Drosophila) [SourceRho-associated, coiled-coil containing protein kinase 1 [Source:HGNC retinal outer segment membrane protein 1 [Source:HGNC Symbol;Acc:RAR-related orphan receptor B [Source:HGNC Symbol;Acc:HGNC:10259]

RP2 retinitis pigmentosa 2 (X-linked recessive) [Source:HGNC Symbol;Acc:Hribose 5-phosphate isomerase A [Source:HGNC Symbol;Acc:HGNC:10297

RPL10 ribosomal protein L10 [Source:HGNC Symbol;Acc:HGNC:10298]ribosomal protein L13 [Source:HGNC Symbol;Acc:HGNC:10303]ribosomal protein L23 [Source:HGNC Symbol;Acc:HGNC:10316]ribosomal protein L28 [Source:HGNC Symbol;Acc:HGNC:10330]ribosomal protein L5 [Source:HGNC Symbol;Acc:HGNC:10360]ribosomal protein, large, P2 [Source:HGNC Symbol;Acc:HGNC:10377]ribophorin II [Source:HGNC Symbol;Acc:HGNC:10382]ribosomal protein S6 [Source:HGNC Symbol;Acc:HGNC:10429]ribosomal protein S6 kinase, 90kDa, polypeptide 1 [Source:HGNC Symbribosomal protein S9 [Source:HGNC Symbol;Acc:HGNC:10442]Ras-related associated with diabetes [Source:HGNC Symbol;Acc:HGNC:1related RAS viral (r-ras) oncogene homolog [Source:HGNC Symbol;Acc:ribosome binding protein 1 [Source:HGNC Symbol;Acc:HGNC:10448]ras responsive element binding protein 1 [Source:HGNC Symbol;Acc:HGRas suppressor protein 1 [Source:HGNC Symbol;Acc:HGNC:10464]rhotekin [Source:HGNC Symbol;Acc:HGNC:10466]RUN and FYVE domain containing 1 [Source:HGNC Symbol;Acc:HGNC:19retinoid X receptor, alpha [Source:HGNC Symbol;Acc:HGNC:10477]receptor-like tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:10481]ryanodine receptor 1 (skeletal) [Source:HGNC Symbol;Acc:HGNC:10483]S100 calcium binding protein A11 [Source:HGNC Symbol;Acc:HGNC:1048S100 calcium binding protein A16 [Source:HGNC Symbol;Acc:HGNC:2044S100 calcium binding protein A2 [Source:HGNC Symbol;Acc:HGNC:10492S100 calcium binding protein A4 [Source:HGNC Symbol;Acc:HGNC:10494S100 calcium binding protein A6 [Source:HGNC Symbol;Acc:HGNC:10496S100 calcium binding protein B [Source:HGNC Symbol;Acc:HGNC:10500]spalt-like transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:10524]spalt-like transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:10526]spalt-like transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:10527]Sin3A-associated protein, 18kDa [Source:HGNC Symbol;Acc:HGNC:10530Sin3A-associated protein, 30kDa [Source:HGNC Symbol;Acc:HGNC:10532squamous cell carcinoma antigen recognized by T cells [Source:HGNC

RHPN1RIN2RIN3RNASE4RNF135RNF149RNF20RNF24RNGTTRNPEPROBO4ROCK1ROM1RORB

RPIA

RPL13RPL23RPL28RPL5RPLP2RPN2RPS6RPS6KA1RPS9RRADRRASRRBP1RREB1RSU1RTKNRUFY1RXRARYKRYR1S100A11S100A16S100A2S100A4S100A6S100BSALL1SALL2SALL3SAP18SAP30SART1















































squamous cell carcinoma antigen recognized by T cells 3 [Source:HGNCSAM and SH3 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:191spermidine/spermine N1-acetyltransferase family member 2 [Source:HSATB homeobox 1 [Source:HGNC Symbol;Acc:HGNC:10541]salvador family WW domain containing protein 1 [Source:HGNC Symbolsecretory carrier membrane protein 2 [Source:HGNC Symbol;Acc:HGNC:secretoglobin, family 1D, member 2 [Source:HGNC Symbol;Acc:HGNC:18sodium channel, voltage gated, type XI alpha subunit [Source:HGNC Syscribbled planar cell polarity protein [Source:HGNC Symbol;Acc:HGNC:3syndecan 4 [Source:HGNC Symbol;Acc:HGNC:10661]serologically defined colon cancer antigen 3 [Source:HGNC Symbol;Accserologically defined colon cancer antigen 8 [Source:HGNC Symbol;Accsidekick cell adhesion molecule 2 [Source:HGNC Symbol;Acc:HGNC:1930serine dehydratase-like [Source:HGNC Symbol;Acc:HGNC:30404]SEC14-like 2 (S. cerevisiae) [Source:HGNC Symbol;Acc:HGNC:10699]SEC24 family member A [Source:HGNC Symbol;Acc:HGNC:10703]SEC24 family member C [Source:HGNC Symbol;Acc:HGNC:10705]Sec61 alpha 1 subunit (S. cerevisiae) [Source:HGNC Symbol;Acc:HGNC:1selenium binding protein 1 [Source:HGNC Symbol;Acc:HGNC:10719]selectin L [Source:HGNC Symbol;Acc:HGNC:10720]sema domain, immunoglobulin domain (Ig), short basic domain, secretsema domain, immunoglobulin domain (Ig), transmembrane domain (TM)sema domain, immunoglobulin domain (Ig), transmembrane domain (TM)sema domain, immunoglobulin domain (Ig), transmembrane domain (TM)sema domain, transmembrane domain (TM), and cytoplasmic domain, (SUMO1/sentrin specific peptidase 7 [Source:HGNC Symbol;Acc:HGNC:30selenoprotein N, 1 [Source:HGNC Symbol;Acc:HGNC:15999]selenoprotein P, plasma, 1 [Source:HGNC Symbol;Acc:HGNC:10751]small EDRK-rich factor 2 [Source:HGNC Symbol;Acc:HGNC:10757]serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsserpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsserpin peptidase inhibitor, clade B (ovalbumin), member 1 [Source:HGserpin peptidase inhibitor, clade B (ovalbumin), member 6 [Source:HGserpin peptidase inhibitor, clade E (nexin, plasminogen activator inhiserpin peptidase inhibitor, clade G (C1 inhibitor), member 1 [Source:sestrin 2 [Source:HGNC Symbol;Acc:HGNC:20746]SEC14 and spectrin domains 1 [Source:HGNC Symbol;Acc:HGNC:18379]SET nuclear proto-oncogene [Source:HGNC Symbol;Acc:HGNC:10760]SET domain, bifurcated 1 [Source:HGNC Symbol;Acc:HGNC:10761]SET domain, bifurcated 2 [Source:HGNC Symbol;Acc:HGNC:20263]SET domain and mariner transposase fusion gene [Source:HGNC Symbolsplicing factor 3a, subunit 3, 60kDa [Source:HGNC Symbol;Acc:HGNC:107splicing factor 3b, subunit 1, 155kDa [Source:HGNC Symbol;Acc:HGNC:1Scm-like with four mbt domains 2 [Source:HGNC Symbol;Acc:HGNC:2025splicing factor proline/glutamine-rich [Source:HGNC Symbol;Acc:HGNC:secreted frizzled-related protein 2 [Source:HGNC Symbol;Acc:HGNC:107sideroflexin 5 [Source:HGNC Symbol;Acc:HGNC:16073]sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) [Sourc

SART3SASH1SAT2SATB1SAV1SCAMP2SCGB1D2SCN11ASCRIBSDC4SDCCAG3SDCCAG8SDK2SDSLSEC14L2SEC24ASEC24CSEC61A1SELENBP1SELLSEMA3BSEMA4BSEMA4CSEMA4DSEMA6ASENP7SEPN1SEPP1SERF2SERPINA3SERPINA5SERPINB1SERPINB6SERPINE2SERPING1SESN2SESTD1SETSETDB1SETDB2SETMARSF3A3SF3B1SFMBT2SFPQSFRP2SFXN5SGCD

















































shugoshin-like 2 (S. pombe) [Source:HGNC Symbol;Acc:HGNC:30812]sphingosine-1-phosphate lyase 1 [Source:HGNC Symbol;Acc:HGNC:10817N-sulfoglucosamine sulfohydrolase [Source:HGNC Symbol;Acc:HGNC:108SH2 domain containing 3C [Source:HGNC Symbol;Acc:HGNC:16884]SH3-domain binding protein 2 [Source:HGNC Symbol;Acc:HGNC:10825]SH3-domain binding protein 4 [Source:HGNC Symbol;Acc:HGNC:10826]SH3-domain GRB2-like endophilin B2 [Source:HGNC Symbol;Acc:HGNC:1SHC (Src homology 2 domain containing) transforming protein 1 [Sourserine hydroxymethyltransferase 1 (soluble) [Source:HGNC Symbol;AccSNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase [Ssiah E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:10857sialic acid binding Ig-like lectin 8 [Source:HGNC Symbol;Acc:HGNC:10877signal-induced proliferation-associated 1 [Source:HGNC Symbol;Acc:HGsignal-induced proliferation-associated 1 like 2 [Source:HGNC Symbol;sirtuin 1 [Source:HGNC Symbol;Acc:HGNC:14929]SIX homeobox 5 [Source:HGNC Symbol;Acc:HGNC:10891]SKI-like proto-oncogene [Source:HGNC Symbol;Acc:HGNC:10897]Src-like-adaptor [Source:HGNC Symbol;Acc:HGNC:10902]solute carrier family 11 (proton-coupled divalent metal ion transportsolute carrier family 12 (potassium/chloride transporter), member 4 solute carrier family 12 (potassium/chloride transporter), member 7 solute carrier family 13 (sodium-dependent dicarboxylate transportersolute carrier family 14 (urea transporter), member 1 (Kidd blood grosolute carrier family 15 (oligopeptide transporter), member 2 [Sourcesolute carrier family 15 (oligopeptide transporter), member 4 [Sourcesolute carrier family 16 (monocarboxylate transporter), member 1 [Sosolute carrier family 16 (monocarboxylate transporter), member 5 [Sosolute carrier family 16, member 9 [Source:HGNC Symbol;Acc:HGNC:235solute carrier family 1 (glial high affinity glutamate transporter), mesolute carrier family 22 (organic cation transporter), member 3 [Soursolute carrier family 22 (organic cation/carnitine transporter), membsolute carrier family 24 (sodium/potassium/calcium exchanger), membsolute carrier family 24 (sodium/potassium/calcium exchanger), membsolute carrier family 25 (mitochondrial carrier; citrate transporter),solute carrier family 25 (aspartate/glutamate carrier), member 13 [Sosolute carrier family 25 (glutamate carrier), member 18 [Source:HGNCsolute carrier family 25 (carnitine/acylcarnitine translocase), membersolute carrier family 25 (mitochondrial carnitine/acylcarnitine carriesolute carrier family 26 (anion exchanger), member 2 [Source:HGNC Sysolute carrier family 26 (anion exchanger), member 7 [Source:HGNC Sysolute carrier family 27 (fatty acid transporter), member 1 [Source:HGsolute carrier family 27 (fatty acid transporter), member 3 [Source:HGsolute carrier family 2 (facilitated glucose transporter), member 1 [Ssolute carrier family 2 (facilitated glucose transporter), member 10 [SLC2A4 regulator [Source:HGNC Symbol;Acc:HGNC:15930]solute carrier family 31 (copper transporter), member 2 [Source:HGNCsolute carrier family 35, member A4 [Source:HGNC Symbol;Acc:HGNC:20solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate tra

SGOL2SGPL1SGSHSH2D3CSH3BP2SH3BP4SH3GLB2SHC1SHMT1SHPRHSIAH1SIGLEC8SIPA1SIPA1L2SIRT1SIX5SKILSLASLC11A1SLC12A4SLC12A7SLC13A3SLC14A1SLC15A2SLC15A4SLC16A1SLC16A5SLC16A9SLC1A3SLC22A3SLC22A5SLC24A1SLC24A4SLC25A1SLC25A13SLC25A18SLC25A20SLC25A29SLC26A2SLC26A7SLC27A1SLC27A3SLC2A1SLC2A10SLC2A4RGSLC31A2SLC35A4SLC35B2

















































solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), membsolute carrier family 35, member F5 [Source:HGNC Symbol;Acc:HGNC:23solute carrier family 38, member 3 [Source:HGNC Symbol;Acc:HGNC:180solute carrier family 39 (zinc transporter), member 1 [Source:HGNC Sysolute carrier family 39, member 11 [Source:HGNC Symbol;Acc:HGNC:14solute carrier family 3 (amino acid transporter heavy chain), member solute carrier family 40 (iron-regulated transporter), member 1 [Soursolute carrier family 41 (magnesium transporter), member 1 [Source:solute carrier family 4 (anion exchanger), member 2 [Source:HGNC Symsolute carrier family 5 (sodium/myo-inositol cotransporter), member

SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 [Sousolute carrier family 7 (anionic amino acid transporter light chain, xsolute carrier family 7 (cationic amino acid transporter, y+ system),solute carrier family 7 (amino acid transporter light chain, L system)solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3solute carrier family 9, subfamily A (NHE9, cation proton antiporter solute carrier organic anion transporter family, member 3A1 [Source:SMAD family member 5 [Source:HGNC Symbol;Acc:HGNC:6771]SWI/SNF related, matrix associated, actin dependent regulator of chrSWI/SNF related, matrix associated, actin dependent regulator of chrSPARC related modular calcium binding 1 [Source:HGNC Symbol;Acc:HGsphingomyelin phosphodiesterase 1, acid lysosomal [Source:HGNC Symsphingomyelin phosphodiesterase 2, neutral membrane (neutral sphinsmoothelin [Source:HGNC Symbol;Acc:HGNC:11126]SMAD specific E3 ubiquitin protein ligase 2 [Source:HGNC Symbol;Acc:synaptosomal-associated protein, 23kDa [Source:HGNC Symbol;Acc:HGNsmall nuclear RNA activating complex, polypeptide 1, 43kDa [Source:SNF related kinase [Source:HGNC Symbol;Acc:HGNC:30598]small nuclear ribonucleoprotein polypeptide G [Source:HGNC Symbol;Asyntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic cSNW domain containing 1 [Source:HGNC Symbol;Acc:HGNC:16696]sorting nexin 24 [Source:HGNC Symbol;Acc:HGNC:21533]sorting nexin 5 [Source:HGNC Symbol;Acc:HGNC:14969]sorting nexin 6 [Source:HGNC Symbol;Acc:HGNC:14970]sorting nexin 7 [Source:HGNC Symbol;Acc:HGNC:14971]sorting nexin 9 [Source:HGNC Symbol;Acc:HGNC:14973]suppressor of cytokine signaling 4 [Source:HGNC Symbol;Acc:HGNC:1939SON DNA binding protein [Source:HGNC Symbol;Acc:HGNC:11183]sortilin-related VPS10 domain containing receptor 2 [Source:HGNC Symsorbitol dehydrogenase [Source:HGNC Symbol;Acc:HGNC:11184]sortilin-related receptor, L(DLR class) A repeats containing [Source:Hsortilin 1 [Source:HGNC Symbol;Acc:HGNC:11186]SRY (sex determining region Y)-box 10 [Source:HGNC Symbol;Acc:HGNC:SRY (sex determining region Y)-box 13 [Source:HGNC Symbol;Acc:HGNC:SRY (sex determining region Y)-box 2 [Source:HGNC Symbol;Acc:HGNC:1

SOX3 SRY (sex determining region Y)-box 3 [Source:HGNC Symbol;Acc:HGNC:1SRY (sex determining region Y)-box 5 [Source:HGNC Symbol;Acc:HGNC:1SRY (sex determining region Y)-box 8 [Source:HGNC Symbol;Acc:HGNC:1

SLC35D2SLC35F5SLC38A3SLC39A1SLC39A11SLC3A2SLC40A1SLC41A1SLC4A2SLC5A3

SLC7A11SLC7A2SLC7A5SLC9A3R1SLC9A9SLCO3A1SMAD5SMARCC1SMARCD2SMOC1SMPD1SMPD2SMTNSMURF2SNAP23SNAPC1SNRKSNRPGSNTB1SNW1SNX24SNX5SNX6SNX7SNX9SOCS4SONSORCS2SORDSORL1SORT1SOX10SOX13SOX2

SOX5SOX8















































SRY (sex determining region Y)-box 9 [Source:HGNC Symbol;Acc:HGNC:1Sp1 transcription factor [Source:HGNC Symbol;Acc:HGNC:11205]SP100 nuclear antigen [Source:HGNC Symbol;Acc:HGNC:11206]SP110 nuclear body protein [Source:HGNC Symbol;Acc:HGNC:5401]SP110 nuclear body protein [Source:HGNC Symbol;Acc:HGNC:5401]Sp3 transcription factor [Source:HGNC Symbol;Acc:HGNC:11208]sperm autoantigenic protein 17 [Source:HGNC Symbol;Acc:HGNC:11210]sperm associated antigen 1 [Source:HGNC Symbol;Acc:HGNC:11212]sperm associated antigen 8 [Source:HGNC Symbol;Acc:HGNC:14105]sperm associated antigen 9 [Source:HGNC Symbol;Acc:HGNC:14524]secreted protein, acidic, cysteine-rich (osteonectin) [Source:HGNC Symspermatogenesis associated 6 [Source:HGNC Symbol;Acc:HGNC:18309]spastic paraplegia 20 (Troyer syndrome) [Source:HGNC Symbol;Acc:HGNspastic paraplegia 7 (pure and complicated autosomal recessive) [Sousphingosine kinase 1 [Source:HGNC Symbol;Acc:HGNC:11240]sphingosine kinase 2 [Source:HGNC Symbol;Acc:HGNC:18859]spire-type actin nucleation factor 1 [Source:HGNC Symbol;Acc:HGNC:30sialophorin [Source:HGNC Symbol;Acc:HGNC:11249]spondin 1, extracellular matrix protein [Source:HGNC Symbol;Acc:HGNCspeckle-type POZ protein [Source:HGNC Symbol;Acc:HGNC:11254]signal peptide peptidase like 2A [Source:HGNC Symbol;Acc:HGNC:30227]signal peptide peptidase like 3 [Source:HGNC Symbol;Acc:HGNC:30424]sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) [sprouty homolog 2 (Drosophila) [Source:HGNC Symbol;Acc:HGNC:11270]spectrin, beta, non-erythrocytic 1 [Source:HGNC Symbol;Acc:HGNC:1127sulfide quinone reductase-like (yeast) [Source:HGNC Symbol;Acc:HGNC:sequestosome 1 [Source:HGNC Symbol;Acc:HGNC:11280]Snf2-related CREBBP activator protein [Source:HGNC Symbol;Acc:HGNC:sterol regulatory element binding transcription factor 1 [Source:HGNC

SRPX sushi-repeat containing protein, X-linked [Source:HGNC Symbol;Acc:HGserine/arginine repetitive matrix 1 [Source:HGNC Symbol;Acc:HGNC:166serine/arginine repetitive matrix 2 [Source:HGNC Symbol;Acc:HGNC:166sperm specific antigen 2 [Source:HGNC Symbol;Acc:HGNC:11319]slingshot protein phosphatase 2 [Source:HGNC Symbol;Acc:HGNC:30580sarcospan [Source:HGNC Symbol;Acc:HGNC:11322]signal sequence receptor, alpha [Source:HGNC Symbol;Acc:HGNC:11323]signal sequence receptor, gamma (translocon-associated protein gamstructure specific recognition protein 1 [Source:HGNC Symbol;Acc:HGNCsuppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interactingsuppression of tumorigenicity 18, zinc finger [Source:HGNC Symbol;Accsuppression of tumorigenicity 5 [Source:HGNC Symbol;Acc:HGNC:11350]stromal antigen 1 [Source:HGNC Symbol;Acc:HGNC:11354]

STAG2 stromal antigen 2 [Source:HGNC Symbol;Acc:HGNC:11355]signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 [STAM binding protein [Source:HGNC Symbol;Acc:HGNC:16950]StAR-related lipid transfer (START) domain containing 7 [Source:HGNCStAR-related lipid transfer (START) domain containing 9 [Source:HGNCsignal transducer and activator of transcription 2, 113kDa [Source:HG

SOX9SP1SP100SP110SP110SP3SPA17SPAG1SPAG8SPAG9SPARCSPATA6SPG20SPG7SPHK1SPHK2SPIRE1SPNSPON1SPOPSPPL2ASPPL3SPRSPRY2SPTBN1SQRDLSQSTM1SRCAPSREBF1

SRRM1SRRM2SSFA2SSH2SSPNSSR1SSR3SSRP1ST13ST18ST5STAG1

STAM2STAMBPSTARD7STARD9STAT2















































signal transducer and activator of transcription 3 (acute-phase responsignal transducer and activator of transcription 5A [Source:HGNC Symbserine/threonine kinase 10 [Source:HGNC Symbol;Acc:HGNC:11388]serine/threonine kinase 3 [Source:HGNC Symbol;Acc:HGNC:11406]serine/threonine kinase 33 [Source:HGNC Symbol;Acc:HGNC:14568]serine/threonine kinase 38 [Source:HGNC Symbol;Acc:HGNC:17847]serine/threonine kinase 38 like [Source:HGNC Symbol;Acc:HGNC:17848]serine/threonine kinase 4 [Source:HGNC Symbol;Acc:HGNC:11408]stomatin [Source:HGNC Symbol;Acc:HGNC:3383]syntaxin 10 [Source:HGNC Symbol;Acc:HGNC:11428]syntaxin 17 [Source:HGNC Symbol;Acc:HGNC:11432]syntaxin binding protein 3 [Source:HGNC Symbol;Acc:HGNC:11446]serine/threonine/tyrosine interacting protein [Source:HGNC Symbol;Acsuccinate-CoA ligase, GDP-forming, beta subunit [Source:HGNC Symbolsulfatase 1 [Source:HGNC Symbol;Acc:HGNC:20391]sulfatase 2 [Source:HGNC Symbol;Acc:HGNC:20392]sulfatase modifying factor 1 [Source:HGNC Symbol;Acc:HGNC:20376]surfeit 2 [Source:HGNC Symbol;Acc:HGNC:11475]surfeit 4 [Source:HGNC Symbol;Acc:HGNC:11476]SWAP switching B-cell complex 70kDa subunit [Source:HGNC Symbol;Acspleen tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:11491]spectrin repeat containing, nuclear envelope 2 [Source:HGNC Symbol;Asynaptojanin 2 [Source:HGNC Symbol;Acc:HGNC:11504]synaptojanin 2 binding protein [Source:HGNC Symbol;Acc:HGNC:18955]synaptopodin 2 [Source:HGNC Symbol;Acc:HGNC:17732]synaptotagmin-like 2 [Source:HGNC Symbol;Acc:HGNC:15585]

SYTL4 synaptotagmin-like 4 [Source:HGNC Symbol;Acc:HGNC:15588]transforming, acidic coiled-coil containing protein 1 [Source:HGNC Sym

TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated faTATA box binding protein (TBP)-associated factor, RNA polymerase I, TATA box binding protein (TBP)-associated factor, RNA polymerase I, TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated faTAF4 RNA polymerase II, TATA box binding protein (TBP)-associated fatransgelin [Source:HGNC Symbol;Acc:HGNC:11553]transgelin 2 [Source:HGNC Symbol;Acc:HGNC:11554]T-cell acute lymphocytic leukemia 1 [Source:HGNC Symbol;Acc:HGNC:11transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) [Source:TAR DNA binding protein [Source:HGNC Symbol;Acc:HGNC:11571]

TAZ tafazzin [Source:HGNC Symbol;Acc:HGNC:11577]TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 [Source:HGNTBC1 domain family, member 5 [Source:HGNC Symbol;Acc:HGNC:19166]

TBL1X transducin (beta)-like 1X-linked [Source:HGNC Symbol;Acc:HGNC:11585]T-box 2 [Source:HGNC Symbol;Acc:HGNC:11597]T-box 3 [Source:HGNC Symbol;Acc:HGNC:11602]transcription elongation factor A (SII), 1 [Source:HGNC Symbol;Acc:HGNtranscription factor 12 [Source:HGNC Symbol;Acc:HGNC:11623]transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:11633]transcription factor 4 [Source:HGNC Symbol;Acc:HGNC:11634]

STAT3STAT5ASTK10STK3STK33STK38STK38LSTK4STOMSTX10STX17STXBP3STYXSUCLG2SULF1SULF2SUMF1SURF2SURF4SWAP70SYKSYNE2SYNJ2SYNJ2BPSYNPO2SYTL2

TACC1

TAF1BTAF1CTAF3TAF4TAGLNTAGLN2TAL1TAP1TARDBP

TBC1D1TBC1D5

TBX2TBX3TCEA1TCF12TCF3TCF4













































transcription factor 7 (T-cell specific, HMG-box) [Source:HGNC Symbol;transcription factor 7-like 2 (T-cell specific, HMG-box) [Source:HGNC Stranscription factor-like 5 (basic helix-loop-helix) [Source:HGNC SymboT-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subtranscobalamin II [Source:HGNC Symbol;Acc:HGNC:11653]thymine-DNA glycosylase [Source:HGNC Symbol;Acc:HGNC:11700]TEA domain family member 1 (SV40 transcriptional enhancer factor) [tektin 1 [Source:HGNC Symbol;Acc:HGNC:15534]tektin 2 (testicular) [Source:HGNC Symbol;Acc:HGNC:11725]telomerase-associated protein 1 [Source:HGNC Symbol;Acc:HGNC:11726telomeric repeat binding factor (NIMA-interacting) 1 [Source:HGNC Sytestis-specific kinase 2 [Source:HGNC Symbol;Acc:HGNC:11732]transferrin [Source:HGNC Symbol;Acc:HGNC:11740]transcription factor A, mitochondrial [Source:HGNC Symbol;Acc:HGNC:1transcription factor B1, mitochondrial [Source:HGNC Symbol;Acc:HGNC:transcription factor CP2-like 1 [Source:HGNC Symbol;Acc:HGNC:17925]transcription factor EB [Source:HGNC Symbol;Acc:HGNC:11753]transforming growth factor, beta 1 [Source:HGNC Symbol;Acc:HGNC:117transforming growth factor beta 1 induced transcript 1 [Source:HGNC transforming growth factor, beta 2 [Source:HGNC Symbol;Acc:HGNC:117transforming growth factor, beta 3 [Source:HGNC Symbol;Acc:HGNC:117transforming growth factor, beta-induced, 68kDa [Source:HGNC Symboltransforming growth factor, beta receptor 1 [Source:HGNC Symbol;Acctransforming growth factor, beta receptor III [Source:HGNC Symbol;AcTGFB-induced factor homeobox 2 [Source:HGNC Symbol;Acc:HGNC:1576THAP domain containing 9 [Source:HGNC Symbol;Acc:HGNC:23192]thrombospondin 3 [Source:HGNC Symbol;Acc:HGNC:11787]THO complex 1 [Source:HGNC Symbol;Acc:HGNC:19070]

THOC2 THO complex 2 [Source:HGNC Symbol;Acc:HGNC:19073]thrombospondin, type I, domain containing 1 [Source:HGNC Symbol;AcTGFB1-induced anti-apoptotic factor 1 [Source:HGNC Symbol;Acc:HGNC:TIA1 cytotoxic granule-associated RNA binding protein-like 1 [Source

TIMP1 TIMP metallopeptidase inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:118TIMP metallopeptidase inhibitor 2 [Source:HGNC Symbol;Acc:HGNC:118TIMP metallopeptidase inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:118TERF1 (TRF1)-interacting nuclear factor 2 [Source:HGNC Symbol;Acc:HGtight junction protein 1 [Source:HGNC Symbol;Acc:HGNC:11827]tight junction protein 2 [Source:HGNC Symbol;Acc:HGNC:11828]thymidine kinase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:118transducin-like enhancer of split 3 [Source:HGNC Symbol;Acc:HGNC:118toll-like receptor 4 [Source:HGNC Symbol;Acc:HGNC:11850]toll-like receptor 5 [Source:HGNC Symbol;Acc:HGNC:11851]

TLR8 toll-like receptor 8 [Source:HGNC Symbol;Acc:HGNC:15632]transmembrane 9 superfamily member 1 [Source:HGNC Symbol;Acc:HGtransmembrane protein 14C [Source:HGNC Symbol;Acc:HGNC:20952]thymopoietin [Source:HGNC Symbol;Acc:HGNC:11875]transmembrane protease, serine 3 [Source:HGNC Symbol;Acc:HGNC:118transmembrane protease, serine 5 [Source:HGNC Symbol;Acc:HGNC:149

TCF7TCF7L2TCFL5TCIRG1TCN2TDGTEAD1TEKT1TEKT2TEP1TERF1TESK2TFTFAMTFB1MTFCP2L1TFEBTGFB1TGFB1I1TGFB2TGFB3TGFBITGFBR1TGFBR3TGIF2THAP9THBS3THOC1

THSD1TIAF1TIAL1

TIMP2TIMP3TINF2TJP1TJP2TK2TLE3TLR4TLR5

TM9SF1TMEM14CTMPOTMPRSS3TMPRSS5














































tenascin C [Source:HGNC Symbol;Acc:HGNC:5318]tumor necrosis factor, alpha-induced protein 3 [Source:HGNC Symbol;Atumor necrosis factor receptor superfamily, member 10a [Source:HGNtumor necrosis factor receptor superfamily, member 10b [Source:HGNtumor necrosis factor receptor superfamily, member 10d, decoy with tumor necrosis factor receptor superfamily, member 14 [Source:HGNC tumor necrosis factor receptor superfamily, member 1A [Source:HGNCtumor necrosis factor receptor superfamily, member 1B [Source:HGNCtumor necrosis factor (ligand) superfamily, member 13b [Source:HGNCTNFAIP3 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:16903]TNFAIP3 interacting protein 2 [Source:HGNC Symbol;Acc:HGNC:19118]transportin 1 [Source:HGNC Symbol;Acc:HGNC:6401]tenascin XB [Source:HGNC Symbol;Acc:HGNC:11976]transducer of ERBB2, 1 [Source:HGNC Symbol;Acc:HGNC:11979]transducer of ERBB2, 2 [Source:HGNC Symbol;Acc:HGNC:11980]thymocyte selection-associated high mobility group box [Source:HGNCtumor protein p53 [Source:HGNC Symbol;Acc:HGNC:11998]tumor protein p53 binding protein 2 [Source:HGNC Symbol;Acc:HGNC:1tumor protein p53 inducible nuclear protein 1 [Source:HGNC Symbol;Atumor protein D52-like 2 [Source:HGNC Symbol;Acc:HGNC:12007]tropomyosin 2 (beta) [Source:HGNC Symbol;Acc:HGNC:12011]translocated promoter region, nuclear basket protein [Source:HGNC Styrosylprotein sulfotransferase 2 [Source:HGNC Symbol;Acc:HGNC:12021transformer 2 alpha homolog (Drosophila) [Source:HGNC Symbol;Acc:HTNFRSF1A-associated via death domain [Source:HGNC Symbol;Acc:HGNCTNF receptor-associated factor 1 [Source:HGNC Symbol;Acc:HGNC:12031TNF receptor-associated factor 3 [Source:HGNC Symbol;Acc:HGNC:12033TNF receptor-associated factor 4 [Source:HGNC Symbol;Acc:HGNC:12034TNF receptor-associated factor 6, E3 ubiquitin protein ligase [Sourcetriggering receptor expressed on myeloid cells 2 [Source:HGNC Symbolthree prime repair exonuclease 1 [Source:HGNC Symbol;Acc:HGNC:1226three prime repair exonuclease 1 [Source:HGNC Symbol;Acc:HGNC:1226

TREX2 three prime repair exonuclease 2 [Source:HGNC Symbol;Acc:HGNC:1227tripartite motif containing 14 [Source:HGNC Symbol;Acc:HGNC:16283]tripartite motif containing 2 [Source:HGNC Symbol;Acc:HGNC:15974]tripartite motif containing 22 [Source:HGNC Symbol;Acc:HGNC:16379]tripartite motif containing 28 [Source:HGNC Symbol;Acc:HGNC:16384]tripartite motif containing 38 [Source:HGNC Symbol;Acc:HGNC:10059]tripartite motif containing 39 [Source:HGNC Symbol;Acc:HGNC:10065]tripartite motif containing 4 [Source:HGNC Symbol;Acc:HGNC:16275]tripartite motif containing 41 [Source:HGNC Symbol;Acc:HGNC:19013]tripartite motif containing 47 [Source:HGNC Symbol;Acc:HGNC:19020]tripartite motif containing 5 [Source:HGNC Symbol;Acc:HGNC:16276]tripartite motif containing 56 [Source:HGNC Symbol;Acc:HGNC:19028]thyroid hormone receptor interactor 10 [Source:HGNC Symbol;Acc:HGNthyroid hormone receptor interactor 4 [Source:HGNC Symbol;Acc:HGNCthyroid hormone receptor interactor 6 [Source:HGNC Symbol;Acc:HGNCtransient receptor potential cation channel, subfamily M, member 3 [

TNCTNFAIP3TNFRSF10ATNFRSF10BTNFRSF10DTNFRSF14TNFRSF1ATNFRSF1BTNFSF13BTNIP1TNIP2TNPO1TNXBTOB1TOB2TOXTP53TP53BP2TP53INP1TPD52L2TPM2TPRTPST2TRA2ATRADDTRAF1TRAF3TRAF4TRAF6TREM2TREX1TREX1

TRIM14TRIM2TRIM22TRIM28TRIM38TRIM39TRIM4TRIM41TRIM47TRIM5TRIM56TRIP10TRIP4TRIP6TRPM3
















































trichorhinophalangeal syndrome I [Source:HGNC Symbol;Acc:HGNC:1234transient receptor potential cation channel, subfamily V, member 1 [testis specific, 10 [Source:HGNC Symbol;Acc:HGNC:14927]tumor suppressing subtransferable candidate 4 [Source:HGNC Symbol;thiosulfate sulfurtransferase (rhodanese) [Source:HGNC Symbol;Acc:HGtetratricopeptide repeat domain 14 [Source:HGNC Symbol;Acc:HGNC:24tetratricopeptide repeat domain 17 [Source:HGNC Symbol;Acc:HGNC:25tetratricopeptide repeat domain 4 [Source:HGNC Symbol;Acc:HGNC:123transcription termination factor, RNA polymerase I [Source:HGNC Symbtweety family member 2 [Source:HGNC Symbol;Acc:HGNC:13877]tubby like protein 3 [Source:HGNC Symbol;Acc:HGNC:12425]twisted gastrulation BMP signaling modulator 1 [Source:HGNC Symbol;thioredoxin interacting protein [Source:HGNC Symbol;Acc:HGNC:16952]tyrosine kinase 2 [Source:HGNC Symbol;Acc:HGNC:12440]thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441]TYRO protein tyrosine kinase binding protein [Source:HGNC Symbol;AcU2 small nuclear RNA auxiliary factor 1 [Source:HGNC Symbol;Acc:HGNCuveal autoantigen with coiled-coil domains and ankyrin repeats [Sourubiquitin associated protein 2 [Source:HGNC Symbol;Acc:HGNC:14185]ubiquitin-conjugating enzyme E2D 3 [Source:HGNC Symbol;Acc:HGNC:12ubiquitin-conjugating enzyme E2H [Source:HGNC Symbol;Acc:HGNC:124ubiquitin-conjugating enzyme E2, J2 [Source:HGNC Symbol;Acc:HGNC:19ubiquitin protein ligase E3B [Source:HGNC Symbol;Acc:HGNC:13478]uridine-cytidine kinase 1 [Source:HGNC Symbol;Acc:HGNC:14859]ubiquitin-fold modifier 1 [Source:HGNC Symbol;Acc:HGNC:20597]UDP-glucose 6-dehydrogenase [Source:HGNC Symbol;Acc:HGNC:12525]ubiquitin-like with PHD and ring finger domains 1 [Source:HGNC Symboubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin proteiunc-5 homolog B (C. elegans) [Source:HGNC Symbol;Acc:HGNC:12568]uracil-DNA glycosylase [Source:HGNC Symbol;Acc:HGNC:12572]Usher syndrome 1C (autosomal recessive, severe) [Source:HGNC Symboubiquitin specific peptidase 1 [Source:HGNC Symbol;Acc:HGNC:12607]ubiquitin specific peptidase 19 [Source:HGNC Symbol;Acc:HGNC:12617]ubiquitin specific peptidase 21 [Source:HGNC Symbol;Acc:HGNC:12620]ubiquitin specific peptidase 3 [Source:HGNC Symbol;Acc:HGNC:12626]ubiquitin specific peptidase 36 [Source:HGNC Symbol;Acc:HGNC:20062]ubiquitin specific peptidase 37 [Source:HGNC Symbol;Acc:HGNC:20063]ubiquitin specific peptidase 40 [Source:HGNC Symbol;Acc:HGNC:20069]ubiquitin specific peptidase 42 [Source:HGNC Symbol;Acc:HGNC:20068]ubiquitin specific peptidase 47 [Source:HGNC Symbol;Acc:HGNC:20076]ubiquitin specific peptidase 53 [Source:HGNC Symbol;Acc:HGNC:29255]ubiquitin specific peptidase 54 [Source:HGNC Symbol;Acc:HGNC:23513]ubiquitin specific peptidase 8 [Source:HGNC Symbol;Acc:HGNC:12631]vesicle-associated membrane protein 3 [Source:HGNC Symbol;Acc:HGNCvesicle-associated membrane protein 5 [Source:HGNC Symbol;Acc:HGNCvesicle-associated membrane protein 8 [Source:HGNC Symbol;Acc:HGNCVANGL planar cell polarity protein 2 [Source:HGNC Symbol;Acc:HGNC:15vascular cell adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:1266

TRPS1TRPV1TSGA10TSSC4TSTTTC14TTC17TTC4TTF1TTYH2TULP3TWSG1TXNIPTYK2TYMSTYROBPU2AF1UACAUBAP2UBE2D3UBE2HUBE2J2UBE3BUCK1UFM1UGDHUHRF1UHRF2UNC5BUNGUSH1CUSP1USP19USP21USP3USP36USP37USP40USP42USP47USP53USP54USP8VAMP3VAMP5VAMP8VANGL2VCAM1

















































vascular endothelial growth factor C [Source:HGNC Symbol;Acc:HGNC:1vasoactive intestinal peptide [Source:HGNC Symbol;Acc:HGNC:12693]Vpr (HIV-1) binding protein [Source:HGNC Symbol;Acc:HGNC:30911]vacuolar protein sorting 13 homolog C (S. cerevisiae) [Source:HGNC Syvacuolar protein sorting 4 homolog A (S. cerevisiae) [Source:HGNC Symvacuolar protein sorting 54 homolog (S. cerevisiae) [Source:HGNC Symbvaccinia related kinase 2 [Source:HGNC Symbol;Acc:HGNC:12719]von Willebrand factor [Source:HGNC Symbol;Acc:HGNC:12726]WW domain containing adaptor with coiled-coil [Source:HGNC Symbol;WAS protein family, member 2 [Source:HGNC Symbol;Acc:HGNC:12733]Williams-Beuren syndrome chromosome region 16 [Source:HGNC SymboWD repeat and FYVE domain containing 2 [Source:HGNC Symbol;Acc:HGWD repeat domain 1 [Source:HGNC Symbol;Acc:HGNC:12754]WD repeat domain 11 [Source:HGNC Symbol;Acc:HGNC:13831]WD repeat domain 34 [Source:HGNC Symbol;Acc:HGNC:28296]WD repeat domain 36 [Source:HGNC Symbol;Acc:HGNC:30696]WD repeat domain 37 [Source:HGNC Symbol;Acc:HGNC:31406]WD repeat domain 6 [Source:HGNC Symbol;Acc:HGNC:12758]wingless-type MMTV integration site family, member 5A [Source:HGNCWD repeat and SOCS box containing 1 [Source:HGNC Symbol;Acc:HGNC:Wilms tumor 1 associated protein [Source:HGNC Symbol;Acc:HGNC:1684WW domain containing oxidoreductase [Source:HGNC Symbol;Acc:HGNCWW domain containing E3 ubiquitin protein ligase 2 [Source:HGNC Symxeroderma pigmentosum, complementation group C [Source:HGNC Symexportin 1 [Source:HGNC Symbol;Acc:HGNC:12825]X-ray repair complementing defective repair in Chinese hamster cells X-ray repair complementing defective repair in Chinese hamster cells Yes-associated protein 1 [Source:HGNC Symbol;Acc:HGNC:16262]YES proto-oncogene 1, Src family tyrosine kinase [Source:HGNC SymbolYY1 transcription factor [Source:HGNC Symbol;Acc:HGNC:12856]zinc finger, BED-type containing 3 [Source:HGNC Symbol;Acc:HGNC:2071zinc finger and BTB domain containing 10 [Source:HGNC Symbol;Acc:HGzinc finger and BTB domain containing 26 [Source:HGNC Symbol;Acc:HG

ZBTB33 zinc finger and BTB domain containing 33 [Source:HGNC Symbol;Acc:HGzinc finger and BTB domain containing 34 [Source:HGNC Symbol;Acc:HGzinc finger CCCH-type, antiviral 1 [Source:HGNC Symbol;Acc:HGNC:23721zinc finger, CCHC domain containing 6 [Source:HGNC Symbol;Acc:HGNC:zinc finger, CW type with PWWP domain 1 [Source:HGNC Symbol;Acc:Hzinc finger, DHHC-type containing 11 [Source:HGNC Symbol;Acc:HGNC:1zinc finger, DHHC-type containing 3 [Source:HGNC Symbol;Acc:HGNC:18zinc finger, DHHC-type containing 7 [Source:HGNC Symbol;Acc:HGNC:18zinc finger, DHHC-type containing 8 [Source:HGNC Symbol;Acc:HGNC:18ZFP36 ring finger protein-like 1 [Source:HGNC Symbol;Acc:HGNC:1107]ZFP36 ring finger protein-like 2 [Source:HGNC Symbol;Acc:HGNC:1108]ZFP62 zinc finger protein [Source:HGNC Symbol;Acc:HGNC:23241]ZFP91 zinc finger protein [Source:HGNC Symbol;Acc:HGNC:14983]

ZFX zinc finger protein, X-linked [Source:HGNC Symbol;Acc:HGNC:12869]zinc finger, FYVE domain containing 1 [Source:HGNC Symbol;Acc:HGNC:

VEGFCVIPVPRBPVPS13CVPS4AVPS54VRK2VWFWACWASF2WBSCR16WDFY2WDR1WDR11WDR34WDR36WDR37WDR6WNT5AWSB1WTAPWWOXWWP2XPCXPO1XRCC3XRCC5YAP1YES1YY1ZBED3ZBTB10ZBTB26

ZBTB34ZC3HAV1ZCCHC6ZCWPW1ZDHHC11ZDHHC3ZDHHC7ZDHHC8ZFP36L1ZFP36L2ZFP62ZFP91

ZFYVE1















































zinc finger, FYVE domain containing 21 [Source:HGNC Symbol;Acc:HGNCzinc fingers and homeoboxes 1 [Source:HGNC Symbol;Acc:HGNC:12871]Zic family member 2 [Source:HGNC Symbol;Acc:HGNC:12873]zinc finger, MYND-type containing 12 [Source:HGNC Symbol;Acc:HGNC:2zinc finger protein 136 [Source:HGNC Symbol;Acc:HGNC:12920]zinc finger protein 160 [Source:HGNC Symbol;Acc:HGNC:12948]zinc finger protein 177 [Source:HGNC Symbol;Acc:HGNC:12966]zinc finger protein 207 [Source:HGNC Symbol;Acc:HGNC:12998]zinc finger protein 211 [Source:HGNC Symbol;Acc:HGNC:13003]zinc finger protein 217 [Source:HGNC Symbol;Acc:HGNC:13009]zinc finger protein 219 [Source:HGNC Symbol;Acc:HGNC:13011]zinc finger protein 22 [Source:HGNC Symbol;Acc:HGNC:13012]zinc finger protein 226 [Source:HGNC Symbol;Acc:HGNC:13019]zinc finger protein 227 [Source:HGNC Symbol;Acc:HGNC:13020]zinc finger protein 23 [Source:HGNC Symbol;Acc:HGNC:13023]zinc finger protein 24 [Source:HGNC Symbol;Acc:HGNC:13032]zinc finger protein 26 [Source:HGNC Symbol;Acc:HGNC:13053]zinc finger protein 274 [Source:HGNC Symbol;Acc:HGNC:13068]

ZNF275 zinc finger protein 275 [Source:HGNC Symbol;Acc:HGNC:13069]zinc finger protein 277 [Source:HGNC Symbol;Acc:HGNC:13070]zinc finger protein 292 [Source:HGNC Symbol;Acc:HGNC:18410]zinc finger protein 3 [Source:HGNC Symbol;Acc:HGNC:13089]zinc finger protein 302 [Source:HGNC Symbol;Acc:HGNC:13848]zinc finger protein 319 [Source:HGNC Symbol;Acc:HGNC:13644]zinc finger protein 337 [Source:HGNC Symbol;Acc:HGNC:15809]zinc finger protein 395 [Source:HGNC Symbol;Acc:HGNC:18737]zinc finger protein 397 [Source:HGNC Symbol;Acc:HGNC:18818]zinc finger protein 404 [Source:HGNC Symbol;Acc:HGNC:19417]zinc finger protein 410 [Source:HGNC Symbol;Acc:HGNC:20144]zinc finger protein 462 [Source:HGNC Symbol;Acc:HGNC:21684]zinc finger protein 471 [Source:HGNC Symbol;Acc:HGNC:23226]zinc finger protein 488 [Source:HGNC Symbol;Acc:HGNC:23535]zinc finger protein 514 [Source:HGNC Symbol;Acc:HGNC:25894]zinc finger protein 521 [Source:HGNC Symbol;Acc:HGNC:24605]zinc finger protein 529 [Source:HGNC Symbol;Acc:HGNC:29328]zinc finger protein 558 [Source:HGNC Symbol;Acc:HGNC:26422]zinc finger protein 561 [Source:HGNC Symbol;Acc:HGNC:28684]zinc finger protein 565 [Source:HGNC Symbol;Acc:HGNC:26726]zinc finger protein 599 [Source:HGNC Symbol;Acc:HGNC:26408]zinc finger protein 608 [Source:HGNC Symbol;Acc:HGNC:29238]zinc finger protein 618 [Source:HGNC Symbol;Acc:HGNC:29416]zinc finger protein 621 [Source:HGNC Symbol;Acc:HGNC:24787]zinc finger protein 625 [Source:HGNC Symbol;Acc:HGNC:30571]zinc finger protein 75a [Source:HGNC Symbol;Acc:HGNC:13146]zinc finger protein 84 [Source:HGNC Symbol;Acc:HGNC:13159]zinc finger, ZZ-type containing 3 [Source:HGNC Symbol;Acc:HGNC:24523

ZFYVE21ZHX1ZIC2ZMYND12ZNF136ZNF160ZNF177ZNF207ZNF211ZNF217ZNF219ZNF22ZNF226ZNF227ZNF23ZNF24ZNF26ZNF274

ZNF277ZNF292ZNF3ZNF302ZNF319ZNF337ZNF395ZNF397ZNF404ZNF410ZNF462ZNF471ZNF488ZNF514ZNF521ZNF529ZNF558ZNF561ZNF565ZNF599ZNF608ZNF618ZNF621ZNF625ZNF75AZNF84ZZZ3














































Supplementary Table S5B: Increased expression of genes in the caudate of HD with p≤0.001 (Hodges et al. 2006)Chromosome Name Gene Start (bp) Gene End (bp)

12 9067664 91162297 122075647 1221442809 104781002 1049282379 137007227 137028922

16 15949577 161430746 43427366 43450430

17 50634777 5069225213 95019829 9530144612 21797401 21941402

1 94418455 9451866614 74285423 7430305618 21650897 2170480514 22598237 22613215

3 43690113 4373437110 26746593 26861087

9 130713946 13088767510 114431113 114685003

3 38103129 3813724218 49782167 4981396017 7217125 722527310 27195214 2724213017 75941507 75979363

3 58505136 585373191 147629652 1476704962 222860934 222944639

19 38647649 387315833 38453851 384931422 9488486 9555792

20 3667965 36822463 64515654 64688000

10 1177318 17374765 7396208 7830081

12 48766194 4878903716 50246137 50318135

8 130780301 1310424267 31052461 311114794 2843857 2930076

10 109996368 1101355654 99304964 993214428 66430185 66471601

20 50888919 509312401 111483348 1115639623 119579268 1195899451 36088875 360939327 44104361 441145621 35930718 36072500

21 43865186 439865361 230702523 2307142971 11736084 117548021 109984686 110023741

11 62433542 625562352 61177418 611912039 127866480 1278777431 33007940 330809969 4709559 4742043

17 19904302 1997834315 85380571 85749358

9 110048598 1101725129 114334156 114394405

10 4963253 510752210 4922564 513522610 5035354 5107686

1 19303965 193121461 19282558 19289250

19 40230317 402855369 113386317 1134013331 18871430 18902781

14 74056850 740844935 126541841 1265954181 165662216 1656988632 73385758 73610793

10 45374176 454461191 110059994 110070700

X 112774503 11284081511 94706431 94876753

3 134355874 1343754799 137174784 1371885494 25377213 25418498

12 121308245 12139989614 20684177 20698971

8 107249482 10749805517 4163907 4263977

7 92246234 9240138413 110878540 110915069

3 15667236 1585977114 102501760 102509799

7 36389806 364537919 97983361 980159432 69013178 692493274 79901149 801254549 73151757 73170393

15 60347134 604028834 78551519 786104512 69644425 69826464

4 121667955 121697113X 15825806 15855014

15 50908672 5100590012 98645141 9873543319 3750819 376169918 10454628 10489948

X 129645259 1296549376 41053304 41064511

22 39040961 390877433 195568702 1955842057 30911855 30925516

18 26852038 2686581820 63272785 6328979322 42796502 4285810611 46677080 4670061510 31805404 31928876

6 129576132 12971022510 24583609 2472366817 38428418 3851239214 32076114 32159728

X 11137543 1166570112 14942017 14961728

8 1823976 1958641X 136665547 136782088

6 156777929 15721077912 45729665 45908040

3 48918821 489863821 150809705 1508767687 99374249 99394801

11 75264182 7535170519 18001132 18014102

5 91368724 9138335915 97960698 97973838

X 2903970 292935112 102957686 102960516

8 61500556 617146409 116425225 117415070

20 32358344 3243931912 50763710 5082112222 39519695 3952268512 14365632 1450293511 108222484 108369102

2 85751344 8578806615 25677273 25865172

3 182793500 1829216351 160115759 1601435911 203626561 203744081

18 57646426 57803101

2 74526645 745299397 69598919 70793068

19 41219203 412617667 99966720 999761576 70856679 709570383 183253244 183298504

21 29194071 2963075116 1333601 134944111 66002079 6600414916 87949244 88118422

2 214725646 21480971114 34752731 34875647

7 73440398 7352227812 56595596 56636816

2 159318979 15961669211 27040725 2712780915 72686179 72738476

3 107522936 1078113241 156641390 1566595321 93561786 93847150

20 53936777 5407059410 125823546 125853695

1 85266248 8527709018 63123346 6332012820 31664452 31723989

2 111119378 11116844719 44747705 44760044

3 187721377 1877457271 147541412 147626216

X 40049815 401773291 156241962 156243321

X 153494939 1535095545 79069717 79089466

12 32106835 323836339 92711363 927648122 127048027 1271073558 22620418 22669148

11 102347211 1023786707 43758680 438073424 78776342 78916372

20 57168748 5726662910 86756650 8693283815 59659146 59689534

3 113211003 1132874592 241558721 241574138

12 111642146 11168598622 49773283 49827512

6 32968660 32981505

9 134030305 13406853519 15235519 1533254516 50313487 50368934

5 138139766 13817898611 66337333 6634512519 17402939 1740564814 93237550 93333092

3 15601341 1564582212 92140278 92145897

1 203305491 2033096026 26365159 263783206 26440472 264534155 181040225 181061523

10 123154277 12317046710 75431453 7656016714 104985775 10501048219 57958437 5797453419 1461143 147955619 38304161 38305009

1 186375758 1864213781 22636506 22639608

17 79022814 7904978811 119338942 11934088312 7080209 709260712 6988259 707103220 33662284 3366561920 3249305 340762521 17788967 1781938619 6677704 6730562

6 31982024 320026816 32014762 320354186 36871870 369289648 40153455 401553089 128819651 1288298219 83938311 839569869 93096218 931132838 60187347 60281412

13 49308650 494441267 134744252 1349707284 113451032 113761927

10 73812501 738745912 85394748 85418432

11 65180566 652120061 223701593 223776018

16 55566672 5556768719 5911707 591620812 75275979 75390928

1 112619173 112671619

7 116811070 1169220495 40841184 40860175

X 41514934 4192346317 75500261 7551558311 105025443 105035250

7 143288215 1433076964 184627696 1846495094 109688622 109703583

10 113679162 1137309075 96525267 96779595

11 34438925 344720627 116524785 1165611847 116287380 116508541

20 33490075 3365003616 67029116 6710105811 119206042 119308149

3 105655461 10586955221 6444869 646804021 43053191 4307694310 68721012 6879237719 46410372 4641358417 35871491 3588079314 99481169 99535044

1 1385711 139932812 48688458 4871699811 66592821 66606019

6 73695785 7382831611 832843 83983112 7470813 7503893

6 109366514 10938255919 35319261 35347355

6 106969831 1069756276 47477789 47627263

11 35138870 3523240212 55725323 5572970717 7579467 758211311 2376177 2397419

3 122055366 122121139X 2691179 2741309

1 100351734 10052027713 114234887 114272723

9 113255835 1132755891 226989865 227318474

17 73283624 7331217519 54465026 54473264

2 173354820 17336899718 66501083 6660413818 27950966 28177446

10 71396934 7181594712 123260971 12327233417 76000906 7600599912 57747727 57756013

9 120388869 12058017011 2883213 2885881

1 50960745 5097463320 5126786 519788722 17178790 1722198920 3783851 3786690

5 90392261 9040978616 75293698 75433485

2 201116104 2011766872 112584240 1125892755 98853985 989289571 147242641 147295766

15 92900189 930280053 53812335 53846390

19 16517889 165425301 203178931 2031867494 54009789 54064690

12 101696947 1017441408 140511298 140517137

10 71964365 7201356416 75472052 7549538415 101175723 10125193214 64914361 6494459115 90229975 9023404714 102341102 10236291619 1259384 127488012 106237877 10630427916 66552563 66566251

1 154974653 15497924916 1444934 147558022 19523024 19527545

6 31730581 317397631 24745357 24844324

21 34669389 347182272 200853009 2008647441 155262868 155278491

14 95181940 9531990613 76990660 77002517

8 1755778 178657211 77514936 77637805

8 27596917 2761503112 22046174 22065674

2 96816245 9683391112 70242994 70354993

4 77713387 778196155 154857553 1548767931 205043197 2050784997 51016212 513168181 230642489 230693982

16 70480568 7052356521 45405137 45513720

7 94394561 944312326 56056590 563940949 114155560 1143125112 227164565 227314792

X 108439844 108697545X 108155607 108439497

9 134641774 13484484321 45981737 4600505021 46098097 46132849

2 237324003 2374143753 99638475 997992261 40300487 40317816

18 316740 5007225 116084991 1164127628 144841042 144853736

22 19941607 1996997511 67435510 6744382112 108645109 10873159616 84565594 8461807710 99711844 99732100

3 149162410 1492220555 173888280 173961976

12 68842197 6897157016 57092537 57148367

8 86484830 865614987 99438922 99457371

11 68754620 688444101 53196429 532141979 129094810 1291111891 197268204 1974784552 207529737 2076034317 28299321 28825894

16 3725054 388072622 20917426 2095374919 18572220 1860774117 30769388 30824776

7 87345681 8739979510 97865000 98030828

3 33113979 3314777311 111908565 11192372213 20403667 20525857

1 109910242 1099309925 150053291 150113372

15 74782057 748031985 149492197 149551552

22 38290691 3839852215 75674322 75712848

1 201483530 20150945612 76858715 7687906010 124984317 125161170

1 84549606 845744801 70411218 704398513 41194837 41260096

11 57753243 578195465 10971840 11904043

17 3636468 366154211 1752752 176399211 66563463 6656884115 78921058 78949574

9 87725519 8773139320 58995185 59007247

7 148697914 14880103613 113208193 11326710811 107326345 10745784410 44370165 4438649317 4733526 4739922

4 74097035 740992934 73995642 739987792 136114349 1361181655 139647299 139683882

16 88643283 886511522 171522247 171558133

15 74337759 743677402 38066973 381099022 218781749 2188152931 59893308 599267904 107931369 1079534576 46549580 46652830

19 15615617 156628251 85580761 85583962

14 59188646 593714056 39792366 399048773 49468703 495356181 155687960 1557390104 99816833 99870154

19 1407569 143568712 51238292 51271362

2 119366921 1193725601 100186919 100249834

6 117453817 11756985810 14897359 1495443212 1946054 2004535

4 182890060 1829179361 85318481 855783636 31727038 31730617

11 47214465 472392406 30876421 309001561 162631373 162787400

22 38483440 385076602 117814650 117832379

20 49219295 492440776 18223868 18264823

11 71428193 714528685 80626228 80654983

10 12068972 1212322514 95086228 95158010

1 222872271 2230059953 38039205 381240253 197042560 197299300

10 77790791 7792652620 36306336 36528637

6 170282206 17030656522 38518949 38570286

5 13690331 139445432 195737703 196068812

17 11598431 119697482 219279267 219286900

10 21756537 220037692 182716041 1827944641 37556919 375668572 229357629 229714558

19 10718079 108334888 25184723 254180821 62454728 62688368

13 98793487 990866252 74549026 74557554

14 72619296 728941162 114442299 1158457521 97077743 979210498 26514275 266581785 147390811 147510056

18 34493290 348918445 172768090 1727711951 221701424 221742176

12 12474210 1256238315 48331011 4834337317 7225341 7234545

2 71453722 716867682 11444375 11466177

16 2223566 223574219 38815422 38832005

9 92493554 925366554 147480917 147544954

11 86244544 862788132 55865967 55924139

11 65866441 658735926 52420308 524957851 155127460 1551348571 155063731 155069553

14 23356402 233657527 55019021 55256620

14 33924231 3446277411 64851642 6488829611 34621093 34661057

Y 20575725 205931542 27364352 27370486

10 70404379 704286183 184314495 184335358

13 40931920 410614404 139028112 139177218

X 130064874 1301107165 95885098 959620717 74027789 740699075 60751791 60844389

11 31509750 3178399812 13196716 1321993916 10528422 1058069819 48321509 4833055310 117542444 117549546

1 225486835 22565314210 95711779 95877266

9 137048098 13705404522 41091786 4118007712 131949920 132081102

2 120013005 12017911910 32267751 32378798

2 148644440 1487875681 225810092 2258455638 27490779 275455646 145501583 145736024

19 11377205 1138434212 15620158 1588232917 39687914 39730426

5 65926475 6608254912 56079857 56103505

19 45407333 4547882813 102844844 10287600113 46771256 46797232

4 158672125 15870962311 128458761 128587558

4 5711197 581430522 29268009 2930052520 46894624 47188844

1 27970344 2808869617 42700275 42745049

5 76716043 767357815 76818933 768353151 169514166 1695865888 81280363 81284777

11 61799625 6182931811 61792980 6186735415 80152490 80186946

3 138608606 138633376X 154506159 154516242

2 58159243 5824137213 98142562 9845517622 45502238 4560113515 48408306 4864584919 9810267 9827816

5 15500196 159397956 145793502 1458147538 123497889 1235412064 174236658 174284264

19 49506816 495263335 141639302 1416514198 11795573 11839309

17 74862497 748730312 36531805 36646087

12 32399529 326460505 142592178 1426980704 122826708 1228982368 38411138 38468834

12 26938383 269666504 1793307 18088724 1009936 10268974 154604134 1546129671 27612064 276352772 163593396 163736012

17 41812680 418232176 35573585 357285837 32957404 33006931

17 18244836 18258916X 154348524 154374638

3 58008400 581722517 128830377 1288592742 152335237 152649834

12 49636499 497081651 171185208 1712126839 129887187 1300431948 43034194 430857885 73444827 73448362

10 97319267 973219159 83242990 83538546

10 48156558 482748703 120392293 120451253

19 676365 68339017 63819433 63830012

9 130578965 13063835216 70454421 70480274

3 180868141 18098275319 35138808 3514310919 35115879 3512432419 35154730 35169883

5 39105236 392745283 45917899 459958246 111660332 1118734528 103298433 1033328661 209675420 209676388

17 80101556 801198794 143336762 143474568

11 78215297 784183484 46035769 461240819 89605013 89606555

14 87837820 879936652 38665910 38741237

16 88813734 888569705 154190730 1544209841 230057990 2302821242 165747591 165794682

12 89519408 8952480621 33503931 33543491

9 86944363 8694718916 90019629 9004497515 45361124 45402327

3 81489699 817621611 89052319 890653601 89106132 891504561 89006666 89022894

19 12891026 1291420712 120127203 12019471019 18868545 18896096

10 47300386 473135478 94249253 94262350

17 44905008 4491693722 37608475 37633564

6 121435692 1214497271 34792998 347957479 83739421 83829516

16 74447427 746071442 120735623 120992653

12 75480680 7550385316 4314761 433959712 109850943 10988048819 47745522 47757058

5 151212150 15127044014 54474484 54489196

6 24774931 247860992 219498867 2195069886 16238580 162955497 2728112 2844324

17 65010715 650568391 109548611 109618321

20 58839718 589111923 179396089 1794515907 93921699 939286101 67701466 67833467

12 64713445 647594476 117318211 1176025423 39096659 39108363

17 30477362 30527592X 133300103 133415490

13 93226842 94407401X 13771031 13938638

9 130053426 1301401697 1044576 10592611 168079543 1681376672 127645864 127652639

16 19856691 1988616717 74424851 7445165317 7311324 7315564

9 136327476 1363596058 144502973 1445071743 49357176 49358600

17 74842023 7486150417 44345246 4435310213 113324164 113364148

9 121207794 12133284311 67583595 67586660

3 120742637 120783069

12 123633739 1236626067 74657667 747606929 133030675 133058503

22 46296741 463308107 65960684 65982314

X 2828788 288281819 48968125 48993310

7 44826791 4484808311 119093854 119095467

5 135333900 1353999141 226061851 226072001

17 75776434 757858931 9234775 92713372 26190635 262447262 26243170 262904687 107168961 1072025293 121631399 1216609271 32292086 323336353 13479724 135064242 239048168 2394016541 156742107 1567669256 138403531 138422197

14 31100112 31207804X 66162549 66268867

2 238238267 2382406621 39624153 396399456 26087281 260983431 70354805 703853392 190189735 190344193

19 46297046 463434337 75533300 75738962

12 122834453 1228629607 139561570 139777778

11 33256672 3335702316 29992321 29996436

6 26055787 260564286 26124145 261391166 26114873 261239266 26196840 261972501 149842204 1498866526 29941260 299458846 31268749 313571586 32948613 329690946 33075926 330872016 32659467 326683836 32552990 325898486 32517343 325302876 30489467 30494205

6 29826967 2983112519 3572777 357908813 30456704 30617597

4 173331695 173335125X 150980509 150990775

1 23801885 2383862021 39342315 39349647

6 79201245 792347382 137964020 138016364

19 18929201 189412617 27170591 271802617 27153716 27157936

12 53985065 5399027912 53990624 54030823

2 176108790 1761199422 10302889 10427617

16 72063224 720772463 149129584 1491737329 96235306 963021521 162790702 162812817

20 3732667 37531116 31815464 318179466 31827735 31830255

14 64535905 645461737 76302544 76304295

11 111912242 11191409319 35754568 3575807912 119178642 119221131

3 122740003 1227938247 47695730 47979581

15 43796142 4380304317 64002594 6402063420 31605283 31606515

2 8678845 86844531 23557918 235597946 19837386 198406842 208236227 208266074

10 1039908 10491706 30743199 307445541 181088712 1810928991 158999968 159055155

17 43006725 4301445610 89301955 8930927611 307631 31527211 319669 327537

6 137197484 1372194497 112422968 1124810173 50287732 50292918

6 159969099 1601135077 45912245 459218742 216672105 2166955254 57030773 57110385

X 131273506 1313997038 42271302 42332653

X 118727572 1187945394 141636599 1417339875 149371324 149404202

13 20702127 207230983 53846580 538658003 9917074 99336302 112773915 1127845906 136999971 137045180

16 27313668 273647781 154405193 1544694505 55935095 55994993

11 6603708 66108742 238170401 238203729

18 11981025 120308837 120950749 1209772162 120346143 1203518087 30697985 307576021 37860697 37947057

11 72223701 7223910519 7112255 729403412 30628988 30695986

1 45694324 4575065015 90388218 90502243

X 154010500 1540199804 184387713 1844745801 234604269 234609525

19 49659569 4966587511 612553 61599913 109752698 10978656816 54283304 54286763

5 52989326 530947792 172427354 172506282

12 55684568 5571604310 32900319 3300579217 75721328 75757818

3 124761948 1249014187 20330702 204157542 230864639 230879248

14 92936914 931163201 226631690 226739323

21 33642400 338998612 24202864 24360714

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16 67154180 671602989 120902393 120929173

14 102777476 10291150017 28743984 2875095811 36487027 36510272

6 41158506 411631863 48446710 484676453 48465811 48467645

X 153444720 1534705879 98069275 981192124 153152342 153339320

11 5689689 573708919 58544091 58550722

6 25962802 259912266 30326479 303437297 99876958 999196005 181222499 181235809

17 75874161 7587857511 5663557 5938619

7 101085439 10109796719 6737925 675152615 64387748 64455303

7 100867138 1008734549 70529063 71446904

8 115408496 11580967317 3565444 3597098

2 98997261 9915496411 2400488 240387822 37010859 37020183

3 180602130 18061782811 43358932 43494933

1 54715822 547426579 132375548 132406851

17 74213514 7426202012 2877223 294114018 9334767 9402420

1 145992435 14599660019 10350529 1038067618 657604 67357819 35904401 3590829521 43092956 4310758715 70654554 70763593

9 33921693 340489494 102794383 1028688967 129830732 1299529491 1253909 1273885

12 109477402 1095367059 131523801 131531268

13 38349849 383636194 39498755 39528311

19 4903080 49621549 6413151 6507054

10 71212570 7130286412 109097574 10911099211 17493895 17544416

1 62436297 624518043 49108046 491209381 161159450 161165723

15 63504511 6359464017 78787381 78841441

2 218450251 2185683612 233475520 2335667827 6104884 6161564

11 11841423 119593234 119212587 119295517

10 73497538 7362595315 50424380 50514419

1 7771269 77814322 85584408 855934122 85561562 855820311 160400586 1604286781 100719742 100739045

4 176683538 1767927276 152750798 1527597653 51395867 51500002

15 61852389 6206047316 69311356 69326939

2 63892146 640190722 57907651 58159920

12 5948874 612477010 28532493 28623112

1 27404226 274901587 75027122 75074228

13 51584455 517677074 10074339 10116949

10 120851175 1209095249 128633661 1286567875 111091716 111130502

10 1049538 11322973 49007062 490159533 55465715 55490539

17 27294076 273159266 159725585 159756319

16 78099413 7921266716 69762306 69941741

3 14145147 141787832 61477849 61538626

14 103697609 1037155042 216107464 216206303

11 102110461 10223342318 721588 81254614 100238298 100282792

5 77072072 770873238 80485619 805262659 122915566 122931500

X 120250752 1202583989 126860665 1268858787 139043520 1391097199 86287733 863544547 100400826 1004289925 795606 8509863 44915257 44976185

16 84974181 8501153522 20129456 2014800714 68787660 68796253

2 43222402 432266095 180847611 180861285

11 58579111 58621042X 24149173 24216255

14 72969451 73027212

14 103715730 1037336688 123248451 123275541

13 99981772 999867731 42430329 42456267

19 12163064 1218988119 53066606 5310343619 9363020 938261717 32350117 3238188619 57630395 5764277920 53567065 5360990714 21090046 2110472210 45000475 4500532619 44165073 4417838119 44207547 4423726816 71447597 7146309518 35332212 3534548212 132986365 13303295219 58183029 58213562

X 153334155 1533601107 112206588 1123430966 87152833 872641967 100064033 100082548

19 34677639 3468639716 57994668 5800045320 25674215 25696841

8 28345585 2840270118 35241030 3526713319 43872363 4390138514 73886617 73932511

9 106863097 10701363419 56507843 5653022110 47365496 47384273

2 95147330 9516541318 25061926 2535219019 36534774 3660527619 8806170 883232819 9604680 962139919 36182060 3624625719 34758076 34773229

5 124636913 1247488079 113876282 1140565913 40524878 40574685

19 12142090 1215672916 3305406 331885212 133037292 133063304

1 77562416 77683419

Supplementary Table S6: HD associated genes collected from various resourcesGenes Experimentally known to involve inAASDHPPT Caudate down, HDsi ABCC10 Caudate UP, Co-expressdb ABHD4 Caudate UP, HDsi ACTB Caudate down , HTT interacting protein ACTN1 Caudate down , HTT interacting protein ACTR1B Caudate down , HTT interacting protein ADAR Co-expressGenefriends, Co-expressdb ADD1 Caudate UP, Co-expressdb, Hdsi, HTT interacting protein ADD2 Caudate down , HTT interacting protein ADD3 Caudate UP, HTT interacting protein ADORA2A /A2AR Caudate down, AOADPRH Caudate UP, Co-expressGenefriends AGPAT3 Caudate UP, Co-expressGenefriends AKT1 HTT interacting proteins and has been shown functionally related ALDOA Caudate down, Hdsi, HTT interacting protein ANAPC1 Caudate down, Co-expressGenefriends ANXA6 Caudate down, Co-expressGenefriends AP1B1 Co-expressdb, HTT interacting protein AP1G1 Caudate down , HTT interacting protein AP2A1 Caudate down , HTT interacting protein AP2A2 Caudate down, Co-expressdb , HTT interacting protein AP2B1 Caudate down , HTT interacting protein AP3D1 Caudate down, Co-expressdb APAF1 Functinally related and observed/identified in separate experiment to be in other categories (See text for details)API5 Caudate down , HTT interacting protein APP Caudate down, HDsi ARF4 Caudate down, HDsi ARFGAP1 Caudate UP, HTT interacting protein ARHGAP1 Caudate UP, HDsi ARHGAP18 Caudate UP, HDsi ARHGEF6 Caudate UP, HTT interacting protein ARHGEF7 Caudate down, Co-expressGenefriends ARL2 Caudate down, HDsi ARNTL Caudate down, HDsi ARPC1A Caudate down, HDsi ARRDC2 Caudate UP, HDsi ASNS Caudate down, HDsi ASPH Caudate UP, HTT interacting protein ASXL1 Caudate UP, Co-expressdb ATM Functinally related and observed/identified in separate experiment to be in other categories (See text for details)ATP1A1 Caudate down , HTT interacting protein

ATP1B1 HTT interacting proteins and has been shown functionally related ATP2A2 Caudate down , HTT interacting protein ATP5A1 Caudate down, Hdsi, HTT interacting protein ATP5B Caudate down , HTT interacting protein ATP5C1 Caudate down, Hdsi, HTT interacting protein ATP5F1 Hdsi, HTT interacting protein ATP6V0A1 Caudate down, Co-expressdb, HDsi ATP6V0E HTT interacting proteins and has been shown functionally related B4GALT6 Caudate down, Co-expressGenefriends BAG1 HTT interacting proteins and has been shown functionally related BAIAP2 Caudate down , HTT interacting protein BAP1 Caudate down, Co-expressdb BATF Caudate down, Co-expressGenefriends BCAN Caudate UP, HTT interacting protein BCAS4 Caudate down, Co-expressGenefriends BCL11B Caudate down , HTT interacting protein BCL2 Caudate UP, Co-expressGenefriends BECN1 HTT interacting proteins and has been shown functionally related BMP2K Caudate UP, HTT interacting protein BTBD9 Caudate down, Co-expressdb BTG1 Caudate UP, HDsi BUB3 Caudate UP, HDsi BZW2 Caudate down , HTT interacting protein CABIN1 Co-expressGenefriends, Co-expressdb CABLES1 Co-expressGenefriends, Co-expressdb CACNA1E Caudate down, HDsi CACNA2D1 Caudate down , HTT interacting protein CALM1 Caudate down , HTT interacting protein CALU Caudate down, HDsi CAMK1D Caudate down, HDsi CAMK2B Caudate down , HTT interacting protein CAMK2G Caudate UP, HTT interacting protein CAPN2 Caudate UP, HDsi CAPZA1 Caudate UP, HTT interacting protein CAPZA2 Caudate UP, HTT interacting protein CAPZB Hdsi, HTT interacting protein CASK Caudate UP, HDsi CASP1 Caudate UP, HTT interacting protein Casp10 HTT interacting proteins and has been shown functionally related CASP2 Caudate UP, HTT interacting protein CASP3 Caudate UP, Hdsi, HTT interacting protein CASP6 Caudate UP, HTT interacting protein CASP7 Caudate UP, HTT interacting protein

CASP8 HTT interacting proteins and has been shown functionally related CAV1 Caudate UP, HTT interacting protein CBFA2T2 Caudate UP, HDsi CBS Caudate UP, HTT interacting protein CCT2 Caudate down , HTT interacting protein CCT4 Hdsi, HTT interacting protein CD22 Caudate UP, Co-expressGenefriends CDH13 HTT interacting proteins and has been shown functionally related CEP250 Co-expressGenefriends, Co-expressdb CEP63/FLJ13386 HTT interacting proteins and has been shown functionally related CHCHD4 Caudate down, HDsi CHD3 Caudate down, Co-expressdb , HTT interacting protein CHD8 Co-expressGenefriends, Co-expressdb CLDN12 Caudate down, HDsi CLEC16A Co-expressGenefriends, Co-expressdb CLTC Caudate down , HTT interacting protein CNR1 AO, Caudate down CNTN1 Caudate down , HTT interacting protein COG1 Caudate down, HDsi COL4A5 Caudate UP, HDsi CORO1B Caudate UP, HTT interacting protein CORO1C Caudate UP, HTT interacting protein COX4I1 Caudate down , HTT interacting protein COX6C Caudate down , HTT interacting protein CPT1B HTT interacting proteins and has been shown functionally related CPT2 Caudate UP, HDsi CREBBP Caudate UP, Co-expressdb, HTT interacting protein CREBL2 Caudate down, HDsi CRNKL1 Caudate down, HDsi CSK Caudate UP, Co-expressGenefriends CTBP1 HTT interacting proteins and has been shown functionally related CTH Caudate UP, HDsi CTNNB1 Caudate UP, HTT interacting protein CTNS Caudate UP, HDsi CTSD Caudate UP, HDsi CUL1 Caudate UP, HDsi CUL2 Caudate down, Hdsi, HTT interacting protein CYFIP2 Caudate down, Co-expressGenefriends, Co-expressdb CYP2C8 Caudate down, HDsi DBN1 Caudate down , HTT interacting protein DCTN1 Caudate down, Co-expressdb , HTT interacting protein DDB1 Co-expressdb, HTT interacting protein DDX24 Caudate down, HDsi

DDX5 Hdsi, HTT interacting protein DHX8 Co-expressdb, HDsi DIAPH1 Caudate down, Co-expressdb, HDsi DLD Caudate down , HTT interacting protein DLG4 Caudate down , HTT interacting protein DNAJA1 Hdsi, HTT interacting protein DNAJA2 Caudate down , HTT interacting protein DNAJB1 Hdsi, HTT interacting protein DNAJC1 Caudate UP, HTT interacting protein DNAJC21 HTT interacting proteins and has been shown functionally related DNALI1 Caudate UP, HTT interacting protein DNM1 Caudate down , HTT interacting protein DNM1L Caudate down , HTT interacting protein also known as DRP1DNM2 Caudate UP, Co-expressdb, HTT interacting protein DOT1L Co-expressGenefriends, Co-expressdb DPYSL2 Caudate UP, HTT interacting protein DRD1 Functinally related and observed/identified in separate experiment to be in other categories (See text for details)DUSP2 Caudate down, Co-expressGenefriends DUSP8 Caudate down, HDsi DYNC1H1 Co-expressdb, HTT interacting protein DYNC1I2 HTT interacting proteins and has been shown functionally related ECH1 Caudate UP, HTT interacting protein EDC4 Co-expressGenefriends, Co-expressdb EEF1A1 HTT interacting proteins and has been shown functionally related EFTUD2 Co-expressdb, HDsi EGFR Caudate UP, HTT interacting protein EGR1 Caudate down , HTT interacting protein EIF2AK2 Hdsi, HTT interacting protein ELK1 Caudate down, Co-expressGenefriends ENTPD1 Caudate UP, Co-expressGenefriends, HDsi ENTPD2 Caudate UP, HDsi ENTPD3 Caudate down, HDsi ENTPD6 Caudate down, HDsi EP400 Caudate UP, Co-expressGenefriends, Co-expressdb EPB41L1 Caudate down , HTT interacting protein EPS8 Caudate UP, HTT interacting protein EWSR1 Caudate UP, HTT interacting protein EZH1 Caudate UP, Co-expressdb EZR HTT interacting proteins and has been shown functionally related FABP3 Caudate down, HDsi FABP5 Caudate UP, HDsi FADS1 Caudate UP, HDsi FBLN1 Caudate UP, HDsi

FEZ1 Caudate down , HTT interacting protein FHOD3 Caudate down, HDsi FLII Caudate UP, Co-expressdb FLNB Caudate UP, Co-expressdb FMNL3 Caudate UP, Co-expressGenefriends FNBP1 Caudate UP, Co-expressGenefriends FNTA Caudate UP, HDsi G3BP2 Caudate down , HTT interacting protein GALNT2 Caudate UP, HDsi GAPDH Hdsi, HTT interacting protein GBF1 Caudate down, Co-expressGenefriends, Co-expressdb GCN1L1 Caudate UP, Co-expressGenefriends, Co-expressdb GCNT1 Caudate down, HDsi GDF10 Caudate UP, HDsi GDF11 Caudate down, HDsi GFAP Caudate UP, HTT interacting protein GGA3 Caudate down, Co-expressdb GIT1 Caudate down , HTT interacting protein GJA1 Caudate UP, HTT interacting protein GLOD4 Hdsi, HTT interacting protein GMDS Caudate down, HDsi GNAI2 HTT interacting proteins and has been shown functionally related GNAZ HTT interacting proteins and has been shown functionally related GNB1 Caudate down , HTT interacting protein GOT1 Caudate down, HDsi GPHN Caudate down, Co-expressGenefriends GPI Caudate down, Hdsi, HTT interacting protein GPM6A Caudate down , HTT interacting protein Gpx6 Functinally related but not obsereved in any one of the categories (See text for details)GRB2 Caudate down , HTT interacting protein GRIN1 Caudate down, HDsi GRIN2A AO, Caudate down, HDsi GSK3B Caudate down, HDsi GSN Caudate UP, HTT interacting protein GSPT1 Caudate down , HTT interacting protein GSS Caudate down, HDsi GSTP1 Caudate UP, HDsi GTF3C5 Caudate UP, HDsi HADHA Caudate UP, HTT interacting protein HDAC1 Functinally related and observed/identified in separate experiment to be in other categories (See text for details)HDAC2 Caudate down, HDsi HDAC3 Functinally related and observed/identified in separate experiment to be in other categories (See text for details)HDLBP Caudate down, HDsi

HIP1 Caudate UP, HTT interacting protein HIST1H2AC Caudate UP, HDsi HMGB1 Caudate UP, HTT interacting protein HMGB2 Caudate UP, HTT interacting protein HMGCR Caudate down, HDsi HSPA2 Caudate UP, HTT interacting protein HSPA4 Hdsi, HTT interacting protein HSPA8 HTT interacting proteins and has been shown functionally related HSPA9 Hdsi, HTT interacting protein HTT AO, Co-expressGenefriends, Co-expressdbHUWE1 Co-expressGenefriends, Co-expressdb HYPK Caudate UP, HTT interacting protein ILK Caudate UP, HDsi INA Caudate down , HTT interacting protein INPP5B Caudate UP, Co-expressGenefriends INPPL1 Caudate UP, Co-expressdb ITPR1 Caudate down , HTT interacting protein KAT2B HTT interacting proteins and has been shown functionally related KCNC1 Caudate down, HDsi KCNN3 Caudate UP, Co-expressGenefriends KCNRG Caudate UP, HDsi KIAA0556 Caudate UP, Co-expressdb KIAA0922 Caudate down, Co-expressdb KIAA1143 Caudate UP, HDsi KIF5C Caudate down , HTT interacting protein LANCL1 Caudate down , HTT interacting protein LDHA Caudate down , HTT interacting protein LMO4 Caudate down, HDsi MAD1L1 Caudate down, Co-expressGenefriends MAF Caudate UP, HDsi MAGED1 Caudate down , HTT interacting protein MAP3K10 Caudate down , HTT interacting protein MAPK1 Caudate down, HDsi MARCKS Caudate UP, HTT interacting protein MAT2A Caudate UP, HDsi MAX Caudate UP, HDsi MBP Caudate UP, HTT interacting protein MCM3AP Co-expressGenefriends, Co-expressdb ME2 Caudate down, Co-expressGenefriends MECP2 Caudate down, Co-expressdb MED15 Co-expressdb, Hdsi, HTT interacting proteinMED23 HTT interacting proteins and has been shown functionally related MEF2D Caudate down , HTT interacting protein

MGAT1 Caudate UP, HDsi MICA Caudate UP, HDsi MLF1 HTT interacting proteins and has been shown functionally related MLF2 Caudate down , HTT interacting protein MLLT4 Caudate UP, HTT interacting protein MRPS5 Caudate UP, HDsi MTOR Co-expressdb, HTT interacting protein MYCBP2 Co-expressGenefriends, HDsi MYEF2 Caudate down, HDsi MYH10 Caudate down , HTT interacting protein MYL6 Caudate UP, HTT interacting protein MYO5A Caudate down , HTT interacting protein MYO6 Caudate UP, HTT interacting protein MYO9B Caudate UP, Co-expressdb NACA Caudate UP, HDsi NAPA Caudate down , HTT interacting protein NAPB Caudate down , HTT interacting protein NCKAP1 Caudate down , HTT interacting protein NCOR1 HTT interacting proteins and has been shown functionally related NCOR2 Caudate UP, Co-expressdb NDRG2 Caudate UP, HTT interacting protein NDUFA8 Caudate down , HTT interacting protein NDUFB10 Caudate down , HTT interacting protein NDUFB8 Caudate down, HDsi NDUFS1 Caudate down , HTT interacting protein NDUFS3 Caudate down , HTT interacting protein NDUFV1 HTT interacting proteins and has been shown functionally related NDUFV2 Caudate down , HTT interacting protein NEDD4L Caudate down, Co-expressdb NEFL Caudate down , HTT interacting protein NEGR1 Caudate down , HTT interacting protein NFKB1 Co-expressGenefriends, HTT interacting protein NFYA Caudate UP, HTT interacting protein NFYC Caudate down , HTT interacting protein NGFR Functinally related but not obsereved in any one of the categories (See text for details)NISCH Caudate down, Co-expressdb NOP14 Co-expressGenefriends, Co-expressdb NR3C1 Caudate UP, HDsi NSF Caudate down , HTT interacting protein NUMA1 Caudate UP, Co-expressdb NUP153 Caudate UP, HDsi NUP160 Caudate UP, HDsi NUP62 Caudate UP, HDsi

NUP98 Caudate UP, HDsi NXT2 Caudate UP, HDsi ODF2L HTT interacting proteins and has been shown functionally related OGT Caudate down, HDsi PACSIN1 Caudate down , HTT interacting protein PAFAH1B1 Caudate down, HDsi PAH Caudate UP, HDsi PAICS Caudate UP, HDsi PARK2 Caudate down , HTT interacting protein PAX6 Caudate UP, HDsi PCLO Caudate down , HTT interacting protein PDE1B Caudate down, HDsi PFKM Caudate down, Hdsi, HTT interacting protein PFN2 Caudate down , HTT interacting protein PGM1 Caudate UP, HDsi PI4KA Co-expressGenefriends, Co-expressdb PIGM Caudate UP, HDsi PIK3R1 Caudate UP, HTT interacting protein PKM Hdsi, HTT interacting protein POLR2A Co-expressdb, HDsi POLR3E Caudate UP, HDsi POMT2 Caudate UP, Co-expressdb POU2AF1 Caudate UP, Co-expressGenefriends POU3F2 Caudate UP, HTT interacting protein PPFIA3 Caudate down , HTT interacting protein PPIB Caudate UP, HTT interacting protein PPIL2 Caudate UP, Co-expressdb PPL HTT interacting proteins and has been shown functionally related PPM1A Caudate down, HDsi PPM1F Caudate UP, HDsi PPP1CA Caudate down , HTT interacting protein PPP1R13B Caudate down, Co-expressdb, HDsi PPP1R16B Caudate down, Co-expressGenefriends PPP1R3D Caudate UP, HDsi PPP2R1B Caudate UP, HDsi PPP2R2A Caudate down, HDsi PRKAA1 (AMPK1/ AMPKα1Functinally related but not obsereved in any one of the categories (See text for details)PRKRA Caudate UP, HTT interacting protein PRPF8 Co-expressGenefriends, Co-expressdb PRRC2A Co-expressGenefriends, Co-expressdb PRRC2B Co-expressGenefriends, Co-expressdb PSMA1 Caudate down, HDsi

HTT interacting proteins and has been shown functionally related PSMC2


PSMD3 Caudate down, HDsi PSMD8 Caudate down, Hdsi, HTT interacting protein PSPC1 Hdsi, HTT interacting protein PTK2B Caudate down, Co-expressGenefriends PTK6 HTT interacting proteins and has been shown functionally related RAB10 Caudate UP, HDsi RAB11A Caudate down, HDsi RAB14 Caudate UP, HTT interacting protein RAB28 Caudate UP, HDsi RAB3A Caudate down , HTT interacting protein RAC1 HTT interacting proteins and has been shown functionally related RAD23B Caudate down , HTT interacting protein RAD51C Caudate down, HDsi RANBP2 Caudate down, HDsi RAP1B Caudate UP, HDsi RAPGEF1 Co-expressGenefriends, Co-expressdb RASA1 Caudate UP, HTT interacting protein RASD2 Caudate down , HTT interacting protein RBM19 Co-expressGenefriends, Co-expressdb RBM5 Caudate UP, Co-expressdb RECQL5 Caudate UP, Co-expressdb REST HTT interacting proteins and has been shown functionally related RIMS4 Caudate down, HDsi RNGTT Caudate UP, Co-expressGenefriends RNMT Caudate down, HDsi RPL13 Caudate UP, HDsi RPL14 Caudate down, HDsi RPL15 Caudate down , HTT interacting protein RPL23 Caudate UP, HDsi RPL6 Hdsi, HTT interacting protein RPL7 Hdsi, HTT interacting protein RPLP2 Caudate UP, Hdsi, HTT interacting protein RPS6 Caudate UP, HTT interacting protein SASH1 Caudate UP, HTT interacting protein SBF1 Caudate down, Co-expressdb SEC16A Co-expressGenefriends, Co-expressdb SEC23A Caudate down, HDsi SEC24C Caudate UP, Co-expressGenefriends, Co-expressdb SEC61A2 Caudate down, HDsi SEPT_7 HTT interacting proteins and has been shown functionally related SF3A3 Caudate UP, Hdsi, HTT interacting protein SF3B2 Co-expressdb, HDsi SF3B3 Caudate down, Co-expressGenefriends, HDsi

SFMBT2 Caudate UP, Co-expressGenefriends SGK1 HTT interacting proteins and has been shown functionally related SGPP2 Caudate down, Co-expressGenefriends SH3GL3 HTT interacting proteins and has been shown functionally related SIN3A Hdsi, HTT interacting protein SIN3B Caudate down, Co-expressdb SIRT1 Caudate UP, HDsi SLC15A4 Caudate UP, Co-expressGenefriends SLC16A1 Caudate UP, HTT interacting protein SLC25A11 Caudate down , HTT interacting protein SLC25A12 Caudate down , HTT interacting protein SLC25A13 Caudate UP, HTT interacting protein SLC25A3 Caudate down , HTT interacting protein SLC25A4 Caudate down, Hdsi, HTT interacting protein SLC2A3/GLUT3 Caudate down, HDsi SLC35F5 Caudate UP, HDsi SLC41A1 Caudate UP, HDsi SMARCA4 Caudate down, HDsi SMARCC2 Co-expressdb, HDsi SMG5 Co-expressdb, HDsi SNAP25 Caudate down, Hdsi, HTT interacting protein SNAP91 Caudate down , HTT interacting protein SNCA Functinally related and observed/identified in separate experiment to be in other categories (See text for details)SNRNP200 Co-expressGenefriends, Co-expressdb SNW1 Caudate UP, HDsi SNX25 Caudate down, Co-expressGenefriends SNX27 Caudate down, HDsi SORBS1 HTT interacting proteins and has been shown functionally related SORCS1 Caudate down, HDsi SP1 Caudate UP, HTT interacting protein SPG20 Caudate UP, HDsi SPG7 Caudate UP, Co-expressdb SPHK2 Caudate UP, HDsi SPON1 Caudate UP, HDsi SQSTM1 Functinally related and observed/identified in separate experiment to be in other categories (See text for details)SRCAP Caudate UP, HDsi SREBF2 Caudate down, Co-expressGenefriends, HDsi SRGAP1 HTT interacting proteins and has been shown functionally related SRGAP2 HTT interacting proteins and has been shown functionally related SRRM2 Caudate UP, Co-expressdb SRRT HTT interacting proteins and has been shown functionally related SSRP1 Caudate UP, HDsi STIP1 Hdsi, HTT interacting protein

STX1A Caudate down, Hdsi, HTT interacting protein STXBP1 Caudate down , HTT interacting protein SUCLA2 Caudate down , HTT interacting protein SUGP2 Co-expressGenefriends, Co-expressdb SUMO1 HTT interacting proteins and has been shown functionally related SUPT5H Co-expressdb, Hdsi, HTT interacting proteinSYMPK Co-expressGenefriends, Co-expressdb SYN1 Caudate down , HTT interacting protein SYP Caudate down , HTT interacting protein SYT1 Caudate down , HTT interacting protein TAF4 Caudate UP, HTT interacting protein TAF4B Caudate down, HDsi TBC1D22A Co-expressGenefriends, Co-expressdb TBC1D5 Caudate UP, Co-expressGenefriends TBCD Caudate down, Co-expressdb TBP HTT interacting proteins and has been shown functionally related TCP1 Caudate down , HTT interacting protein TEKT1 Caudate UP, HDsi TFEB Caudate UP, Co-expressGenefriends TGM2 HTT interacting proteins and has been shown functionally related THY1 Caudate down , HTT interacting protein TJP2 Caudate UP, HTT interacting protein TLN1 HTT interacting proteins and has been shown functionally related TMOD2 Caudate down , HTT interacting protein TMPRSS5 Caudate UP, HDsi TNFRSF8 Caudate down, Co-expressGenefriends TNFSF13B Caudate UP, HDsi TNIP1 Caudate UP, Co-expressGenefriends TOMM22 Caudate down, HDsi TP53 Caudate UP, HTT interacting protein TP53INP1 Caudate UP, HDsi TPM2 Caudate UP, HTT interacting protein TPR Caudate UP, HTT interacting protein TRAF1 Caudate UP, Co-expressGenefriends TRAF3 Caudate UP, Co-expressGenefriends, HDsi TRAF6 Caudate UP, HTT interacting protein TRAP1 Caudate down, Co-expressGenefriends TRIO Caudate down , HTT interacting protein TRIP10 Caudate UP, HTT interacting protein TRRAP Co-expressGenefriends, HDsi TSC2 Caudate down, Co-expressdb TTC17 Caudate UP, Co-expressdb TUBB Caudate down , HTT interacting protein

TUBG1 Hdsi, HTT interacting protein TYK2 Caudate UP, Co-expressGenefriends, Co-expressdb UBA1 Co-expressdb, HDsi UBD HTT interacting proteins and has been shown functionally related UBE2D2 Caudate down, HDsi UBE2H Caudate UP, HDsi UBE2K Hdsi, HTT interacting protein Ube3a Functinally related but not obsereved in any one of the categories (See text for details)UBQLN1 HTT interacting proteins and has been shown functionally related UBQLN2 Caudate down , HTT interacting protein UBR4 Co-expressGenefriends, Co-expressdb UCHL3 Caudate down, HDsi UGP2 Caudate down, HDsi UPF1 Co-expressdb, HDsi UQCRC2 Caudate down , HTT interacting protein USP1 Caudate UP, HDsi USP14 Functinally related but not obsereved in any one of the categories (See text for details)USP19 Caudate UP, Co-expressdb USP21 Caudate UP, HDsi USP40 Caudate UP, Co-expressdb USP7 Co-expressdb, HDsi USP8 Caudate UP, HDsi USP9X HTT interacting proteins and has been shown functionally related VAMP2 Caudate down , HTT interacting protein VAPA Caudate down , HTT interacting protein VDAC1 Caudate down , HTT interacting protein VDAC2 HTT interacting proteins and has been shown functionally related VDAC3 Caudate down , HTT interacting protein VPRBP Caudate UP, HDsi VPS35 Caudate down , HTT interacting protein VPS39 Co-expressGenefriends, Co-expressdb VPS54 Caudate UP, HDsi WDR6 Caudate UP, Co-expressdb WHSC1 Caudate down, Co-expressdb WNT10A Caudate down, Co-expressGenefriends XPC Caudate UP, Co-expressGenefriends, Co-expressdb XRCC6 HTT interacting proteins and has been shown functionally related YBX1 Hdsi, HTT interacting protein YWHAB Caudate down , HTT interacting protein YWHAE Caudate down, Hdsi, HTT interacting protein YWHAG Caudate down , HTT interacting protein YWHAH Caudate down , HTT interacting protein YWHAZ Caudate down, Hdsi, HTT interacting protein

ZDHHC17 HTT interacting proteins and has been shown functionally related ZFP36L2 Caudate UP, HDsi ZFYVE27 Caudate down, Co-expressdb ZMYND8 HTT interacting proteins and has been shown functionally related ZNF207 Caudate UP, HDsi ZNF24 Caudate UP, HDsi ZNF292 Caudate UP, Co-expressGenefriends ZNF91 Caudate down , HTT interacting protein ZZEF1 Co-expressGenefriends, Co-expressdb

Functinally related and observed/identified in separate experiment to be in other categories (See text for details)


also known as DRP1


Functinally related but not obsereved in any one of the categories (See text for details)



Supplementary Table S7A: Enriched Biological processes with HD associated genesId Items Items_Details Support

191 GO:0048011 nerve growth factor receptor s 331 GO:0006915 apoptotic process (BP) 50

360 GO:0016032 viral reproduction (BP) 3426 GO:0044419 interspecies interaction betw 34

7 GO:0007165 signal transduction (BP) 58310 GO:0042981 regulation of apoptotic proces 23110 GO:0008285 negative regulation of cell prol 29121 GO:0007596 blood coagulation (BP) 33172 GO:0006511 ubiquitin-dependent protein ca 20166 GO:0007268 synaptic transmission (BP) 30

34 GO:0045944 positive regulation of transcr 36105 GO:0010467 gene expression (BP) 30

1006 GO:0007173 epidermal growth factor recep 14331 GO:0007411 axon guidance (BP) 25182 GO:0030036 actin cytoskeleton organizatio 17

91 GO:0016192 vesicle-mediated transport (BP 20641 GO:0007269 neurotransmitter secretion (BP 12147 GO:0006006 glucose metabolic process (BP 15457 GO:0008219 cell death (BP) 18287 GO:0022904 respiratory electron transport 14344 GO:0016070 RNA metabolic process (BP) 22775 GO:0006897 endocytosis (BP) 15104 GO:0005975 carbohydrate metabolic proces 23

43 GO:0006921 cellular component disassembly 11368 GO:0016071 mRNA metabolic process (BP) 20345 GO:0043066 negative regulation of apoptot 22206 GO:0006950 response to stress (BP) 17

29 GO:0006810 transport (BP) 33134 GO:0007264 small GTPase mediated signal 23

98 GO:0045892 negative regulation of transcr 2622 GO:0007399 nervous system development ( 26

156 GO:0015031 protein transport (BP) 26411 GO:0006184 GTP catabolic process (BP) 16

99 GO:0042493 response to drug (BP) 22219 GO:0000278 mitotic cell cycle (BP) 22787 GO:0032868 response to insulin stimulus (B 11303 GO:0006886 intracellular protein transport 17442 GO:0016568 chromatin modification (BP) 18300 GO:0006916 anti-apoptosis (BP) 17405 GO:0008629 induction of apoptosis by intrac 9

1509 GO:0048169 regulation of long-term neurona 7125 GO:0045893 positive regulation of transcr 26374 GO:0006457 protein folding (BP) 16152 GO:0016044 cellular membrane organizatio 12208 GO:0006917 induction of apoptosis (BP) 16694 GO:0015758 glucose transport (BP) 10

494 GO:0042059 negative regulation of epiderm 8184 GO:0008286 insulin receptor signaling pat 14288 GO:0006120 mitochondrial electron transp 8151 GO:0051056 regulation of small GTPase med 15149 GO:0006754 ATP biosynthetic process (BP) 8723 GO:0008624 induction of apoptosis by extra 12

64 GO:0043065 positive regulation of apoptoti 15805 GO:0043525 positive regulation of neuron 8

0 GO:0006355 regulation of transcription, D 53409 GO:0030168 platelet activation (BP) 17578 GO:0006892 post-Golgi vesicle-mediated tr 8

62 GO:0000122 negative regulation of transcr 231104 GO:0014047 glutamate secretion (BP) 6

122 GO:0006366 transcription from RNA polyme 1940 GO:0050796 regulation of insulin secretion 10

414 GO:0007568 aging (BP) 12587 GO:0000086 G2/M transition of mitotic cell 12

1110 GO:0008542 visual learning (BP) 7157 GO:0044267 cellular protein metabolic proc 18

38 GO:0006112 energy reserve metabolic proc 11382 GO:0006200 ATP catabolic process (BP) 10560 GO:0044255 cellular lipid metabolic process 12207 GO:0007050 cell cycle arrest (BP) 12

1133 GO:0006469 negative regulation of protein 861 GO:0031175 neuron projection developmen 9

215 GO:0006412 translation (BP) 16140 GO:0007584 response to nutrient (BP) 10

88 GO:0048015 phosphatidylinositol-mediated 9550 GO:0016188 synaptic vesicle maturation (B 4

89 GO:0000398 nuclear mRNA splicing, via spl 13948 GO:0045768 positive regulation of anti-apo 7622 GO:0006094 gluconeogenesis (BP) 7695 GO:0008645 hexose transport (BP) 7

1474 GO:0048041 focal adhesion assembly (BP) 5874 GO:0050690 regulation of defense response 6

1202 GO:0005979 regulation of glycogen biosynt 4198 GO:0010976 positive regulation of neuron 7

1768 GO:0061198 fungiform papilla formation (B 31803 GO:0010807 regulation of synaptic vesicle 3

20 GO:0006508 proteolysis (BP) 24739 GO:0033077 T cell differentiation in thymus 6370 GO:0000075 cell cycle checkpoint (BP) 11693 GO:0010827 regulation of glucose transport 6324 GO:0051726 regulation of cell cycle (BP) 8557 GO:0019058 viral infectious cycle (BP) 9

1216 GO:0007016 cytoskeletal anchoring at pla 41589 GO:0001963 synaptic transmission, dopamin 4

342 GO:0043123 positive regulation of I-kappa 11

458 GO:0045471 response to ethanol (BP) 9696 GO:0051028 mRNA transport (BP) 7106 GO:0006414 translational elongation (BP) 9415 GO:0018105 peptidyl-serine phosphorylatio 7

14 GO:0006468 protein phosphorylation (BP) 1930 GO:0055085 transmembrane transport (BP) 25

807 GO:0008635 activation of cysteine-type en 4376 GO:0010977 negative regulation of neuron 5465 GO:0031295 T cell costimulation (BP) 8190 GO:0030154 cell differentiation (BP) 22571 GO:0007420 brain development (BP) 12153 GO:0051592 response to calcium ion (BP) 7545 GO:0051291 protein heterooligomerization 6992 GO:0046889 positive regulation of lipid bio 3

1723 GO:0048489 synaptic vesicle transport (BP) 31767 GO:0060789 hair follicle placode formation 3

667 GO:0030163 protein catabolic process (BP) 6397 GO:0042776 mitochondrial ATP synthesis c 4

1475 GO:0015986 ATP synthesis coupled proton 41593 GO:0051924 regulation of calcium ion trans 4

558 GO:0019083 viral transcription (BP) 8177 GO:0000209 protein polyubiquitination (BP 9710 GO:0016079 synaptic vesicle exocytosis (BP 4

1029 GO:0017157 regulation of exocytosis (BP) 41180 GO:0007569 cell aging (BP) 5

521 GO:0006461 protein complex assembly (BP) 9730 GO:0042593 glucose homeostasis (BP) 7522 GO:0007417 central nervous system devel 9556 GO:0006415 translational termination (BP) 8

57 GO:0006357 regulation of transcription fr 13498 GO:0001954 positive regulation of cell-mat 4

1138 GO:0001662 behavioral fear response (BP) 4366 GO:0006977 DNA damage response, signal tr 7

90 GO:0008380 RNA splicing (BP) 141158 GO:0051016 barbed-end actin filament cap 3

163 GO:0043200 response to amino acid stimulu 5592 GO:0001975 response to amphetamine (BP 5277 GO:0034329 cell junction assembly (BP) 8491 GO:0043407 negative regulation of MAP kina 5881 GO:0007094 mitotic cell cycle spindle asse 5986 GO:0032880 regulation of protein localizati 5189 GO:0007265 Ras protein signal transduction 7

24 GO:0008283 cell proliferation (BP) 15142 GO:0009408 response to heat (BP) 6170 GO:0016579 protein deubiquitination (BP) 5249 GO:0007611 learning or memory (BP) 5145 GO:0031018 endocrine pancreas developme 9700 GO:0006936 muscle contraction (BP) 8

1139 GO:0044070 regulation of anion transport ( 31295 GO:0031065 positive regulation of histone 31320 GO:0014002 astrocyte development (BP) 31447 GO:0048268 clathrin coat assembly (BP) 31525 GO:0045792 negative regulation of cell size 3

697 GO:0008344 adult locomotory behavior (BP 51429 GO:0042220 response to cocaine (BP) 4

365 GO:0051439 regulation of ubiquitin-protein 7541 GO:0007409 axonogenesis (BP) 7

13 GO:0007015 actin filament organization (BP 5183 GO:0008652 cellular amino acid biosyntheti 5

1119 GO:0021766 hippocampus development (BP 5459 GO:0006974 response to DNA damage stimu 9612 GO:0006338 chromatin remodeling (BP) 6

1279 GO:0016575 histone deacetylation (BP) 41299 GO:0006606 protein import into nucleus (B 5

187 GO:0008543 fibroblast growth factor recep 756 GO:0033151 V(D)J recombination (BP) 3

985 GO:0055089 fatty acid homeostasis (BP) 31442 GO:0006853 carnitine shuttle (BP) 31483 GO:0014049 positive regulation of glutamat 3

139 GO:0032869 cellular response to insulin sti 6284 GO:0006091 generation of precursor metab 6487 GO:0006470 protein dephosphorylation (BP 8623 GO:0051402 neuron apoptosis (BP) 4706 GO:0051017 actin filament bundle assembly 4

52 GO:0006288 base-excision repair, DNA ligat 2951 GO:0009181 purine ribonucleoside diphosph 2

1477 GO:0016239 positive regulation of macroa 21494 GO:0001956 positive regulation of neurotra 21638 GO:0070814 hydrogen sulfide biosynthetic 21650 GO:0000715 nucleotide-excision repair, D 21742 GO:0018394 peptidyl-lysine acetylation (BP 21758 GO:0014733 regulation of skeletal muscle 21781 GO:0031999 negative regulation of fatty ac 21799 GO:0030997 regulation of centriole-centrio 21844 GO:0035494 SNARE complex disassembly (B 21869 GO:0048499 synaptic vesicle membrane org 2

364 GO:0031145 anaphase-promoting complex-d 7438 GO:0008104 protein localization (BP) 6306 GO:0060079 regulation of excitatory posts 4

1197 GO:0048167 regulation of synaptic plasticit 4588 GO:0050885 neuromuscular process control 5267 GO:0045663 positive regulation of myoblast 3

1388 GO:0051593 response to folic acid (BP) 3712 GO:0009267 cellular response to starvation 4808 GO:0001836 release of cytochrome c from 4143 GO:0001666 response to hypoxia (BP) 10

1342 GO:0051225 spindle assembly (BP) 4220 GO:0000082 G1/S transition of mitotic cell 9561 GO:0031000 response to caffeine (BP) 3744 GO:0035235 ionotropic glutamate receptor 3

1067 GO:0051881 regulation of mitochondrial m 31353 GO:0060766 negative regulation of androge 31587 GO:0042417 dopamine metabolic process ( 31696 GO:0019226 transmission of nerve impulse 3

111 GO:0045786 negative regulation of cell cycl 5136 GO:0007049 cell cycle (BP) 17

19 GO:0008360 regulation of cell shape (BP) 781 GO:0046777 protein autophosphorylation ( 9

359 GO:0051436 negative regulation of ubiquitin 6664 GO:0009611 response to wounding (BP) 6

37 GO:0006464 protein modification process ( 91011 GO:0042149 cellular response to glucose st 31096 GO:0031293 membrane protein intracellula 31542 GO:0006476 protein deacetylation (BP) 3

285 GO:0016567 protein ubiquitination (BP) 9468 GO:0007626 locomotory behavior (BP) 6150 GO:0006096 glycolysis (BP) 5632 GO:0006928 cellular component movement 7721 GO:0050872 white fat cell differentiation (B 3883 GO:0090004 positive regulation of establi 3

1013 GO:0032007 negative regulation of TOR sig 31347 GO:0046034 ATP metabolic process (BP) 3

608 GO:0031623 receptor internalization (BP) 41039 GO:0015810 aspartate transport (BP) 21040 GO:0043490 malate-aspartate shuttle (BP) 21092 GO:0018076 N-terminal peptidyl-lysine acet 21307 GO:0051097 negative regulation of helicase 21376 GO:0015867 ATP transport (BP) 21379 GO:0010040 response to iron(II) ion (BP) 21384 GO:0071286 cellular response to magnesiu 21527 GO:0051668 localization within membrane 21818 GO:0006344 maintenance of chromatin sile 2

361 GO:0051437 positive regulation of ubiquitin 6296 GO:0051281 positive regulation of release 3317 GO:0045807 positive regulation of endocyto 3910 GO:0000132 establishment of mitotic spindl 3

1229 GO:0048009 insulin-like growth factor rece 31236 GO:0050999 regulation of nitric-oxide synth 31413 GO:0060291 long-term synaptic potentiatio 3

565 GO:0006520 cellular amino acid metabolic 5879 GO:0007612 learning (BP) 4

1123 GO:0006635 fatty acid beta-oxidation (BP) 4275 GO:0016337 cell-cell adhesion (BP) 6698 GO:0050790 regulation of catalytic activity 5

55 GO:0045087 innate immune response (BP) 13890 GO:0033572 transferrin transport (BP) 4930 GO:0010332 response to gamma radiation ( 4

27 GO:0006986 response to unfolded protein ( 518 GO:0030335 positive regulation of cell migr 7

613 GO:0006351 transcription, DNA-dependent 7767 GO:0006631 fatty acid metabolic process (B 6362 GO:0042176 regulation of protein catabolic 3

1048 GO:0055074 calcium ion homeostasis (BP) 3175 GO:0070936 protein K48-linked ubiquitinat 4197 GO:0043524 negative regulation of neuron 6144 GO:0051707 response to other organism (B 2790 GO:0046626 regulation of insulin receptor 2880 GO:0015853 adenine transport (BP) 2

1189 GO:0045040 protein import into mitochond 21252 GO:0060547 negative regulation of necrotic 21387 GO:0006670 sphingosine metabolic process 21476 GO:0006172 ADP biosynthetic process (BP) 21535 GO:0051534 negative regulation of NFAT pr 21559 GO:0031558 induction of apoptosis in resp 21624 GO:0050667 homocysteine metabolic proce 21652 GO:0070141 response to UV-A (BP) 21766 GO:0070932 histone H3 deacetylation (BP) 2

240 GO:0001782 B cell homeostasis (BP) 3726 GO:0050771 negative regulation of axonoge 3

1410 GO:0016043 cellular component organizati 3662 GO:0002576 platelet degranulation (BP) 6891 GO:0015991 ATP hydrolysis coupled proton 4923 GO:0048538 thymus development (BP) 4

59 GO:0043085 positive regulation of catalytic 5173 GO:0006281 DNA repair (BP) 12283 GO:0005978 glycogen biosynthetic process 3304 GO:0035249 synaptic transmission, glutama 3379 GO:0030041 actin filament polymerization 3574 GO:0019216 regulation of lipid metabolic p 3976 GO:0045664 regulation of neuron differenti 3330 GO:0031667 response to nutrient levels (BP 4421 GO:0040007 growth (BP) 4294 GO:0030308 negative regulation of cell gro 7347 GO:0009725 response to hormone stimulus 5906 GO:0000236 mitotic prometaphase (BP) 6602 GO:0070588 calcium ion transmembrane tr 4

1058 GO:0051693 actin filament capping (BP) 31548 GO:0030048 actin filament-based movemen 3

162 GO:0010243 response to organic nitrogen ( 4770 GO:0033138 positive regulation of peptidyl 4809 GO:0051084 'de novo' posttranslational pro 4128 GO:0050852 T cell receptor signaling pathw 6

493 GO:0010642 negative regulation of platele 2733 GO:0002309 T cell proliferation involved 2897 GO:0033689 negative regulation of osteobla 2

1031 GO:0007021 tubulin complex assembly (BP) 21072 GO:0018022 peptidyl-lysine methylation (B 21203 GO:0005981 regulation of glycogen cataboli 21393 GO:0032469 endoplasmic reticulum calcium 21546 GO:0031659 positive regulation of cyclin-d 21583 GO:0035308 negative regulation of protein 21800 GO:0070389 chaperone cofactor-dependent 2

258 GO:0006959 humoral immune response (BP 410 GO:0007155 cell adhesion (BP) 18

313 GO:0007067 mitosis (BP) 9387 GO:0030100 regulation of endocytosis (BP) 3719 GO:0009416 response to light stimulus (BP) 3738 GO:0007369 gastrulation (BP) 3

1014 GO:0046320 regulation of fatty acid oxidati 3371 GO:0030512 negative regulation of transfo 4718 GO:0042733 embryonic digit morphogenesis 4202 GO:0006493 protein O-linked glycosylation 3336 GO:0071479 cellular response to ionizing ra 3920 GO:0046686 response to cadmium ion (BP) 3

1191 GO:0030032 lamellipodium assembly (BP) 31289 GO:0046329 negative regulation of JNK cas 3

665 GO:0006396 RNA processing (BP) 658 GO:0051103 DNA ligation involved in DNA r 2

577 GO:0016081 synaptic vesicle docking involv 2735 GO:0006924 activation-induced cell death of 2

1141 GO:0007270 neuron-neuron synaptic transm 21159 GO:0010592 positive regulation of lamelli 21162 GO:0002360 T cell lineage commitment (BP 21163 GO:0002326 B cell lineage commitment (BP 21206 GO:0047496 vesicle transport along microt 21210 GO:0030388 fructose 1,6-bisphosphate met 21256 GO:0032872 regulation of stress-activated 21278 GO:0042428 serotonin metabolic process ( 21334 GO:0009913 epidermal cell differentiation 21335 GO:0014067 negative regulation of phospha 21350 GO:0003407 neural retina development (BP 21381 GO:0001818 negative regulation of cytokin 21427 GO:0070933 histone H4 deacetylation (BP) 21489 GO:0007097 nuclear migration (BP) 21642 GO:0001964 startle response (BP) 21699 GO:0034333 adherens junction assembly (B 2

428 GO:0006368 transcription elongation from 5155 GO:0002474 antigen processing and present 6717 GO:0007266 Rho protein signal transductio 4

1021 GO:0048873 homeostasis of number of cells 3

1049 GO:0031647 regulation of protein stability 31095 GO:0016573 histone acetylation (BP) 31296 GO:0000060 protein import into nucleus, tr 3

907 GO:0000087 M phase of mitotic cell cycle ( 663 GO:0050918 positive chemotaxis (BP) 386 GO:2000379 positive regulation of reactiv 3

282 GO:0005977 glycogen metabolic process (B 3866 GO:0006090 pyruvate metabolic process (B 3

1074 GO:0072593 reactive oxygen species metabo 31360 GO:0000718 nucleotide-excision repair, D 3

167 GO:0030334 regulation of cell migration (BP 4196 GO:0000186 activation of MAPKK activity (B 4127 GO:0051897 positive regulation of protein 4660 GO:0043588 skin development (BP) 4971 GO:0043507 positive regulation of JUN kinas 3829 GO:0031115 negative regulation of microtu 2843 GO:0010870 positive regulation of receptor 2892 GO:0048172 regulation of short-term neuron 2918 GO:0042053 regulation of dopamine metabo 2

1084 GO:0071480 cellular response to gamma rad 21134 GO:2000114 regulation of establishment of c 21294 GO:0007435 salivary gland morphogenesis 21352 GO:0090201 negative regulation of release 21458 GO:0045822 negative regulation of heart co 21521 GO:0010832 negative regulation of myotube 21606 GO:0045945 positive regulation of transcr 2

643 GO:0009636 response to toxin (BP) 51222 GO:0002218 activation of innate immune r 4

549 GO:0048662 negative regulation of smooth m 3576 GO:0006944 cellular membrane fusion (BP) 3692 GO:0001892 embryonic placenta developme 3

1199 GO:0000188 inactivation of MAPK activity ( 31277 GO:0031069 hair follicle morphogenesis (BP 3

176 GO:0042787 protein ubiquitination involve 4386 GO:0071363 cellular response to growth fac 4259 GO:0002224 toll-like receptor signaling pa 5

12 GO:0030838 positive regulation of actin fi 351 GO:0006309 DNA fragmentation involved in 3

562 GO:0018107 peptidyl-threonine phosphoryl 3769 GO:0032092 positive regulation of protein 3924 GO:0006890 retrograde vesicle-mediated tr 3960 GO:0009966 regulation of signal transducti 3

1220 GO:0045931 positive regulation of mitotic c 34 GO:0007010 cytoskeleton organization (BP) 6

322 GO:0050900 leukocyte migration (BP) 665 GO:0030324 lung development (BP) 5

120 GO:0031929 TOR signaling cascade (BP) 2590 GO:0019255 glucose 1-phosphate metabolic 2

615 GO:0010224 response to UV-B (BP) 2630 GO:0031669 cellular response to nutrient le 2966 GO:0033591 response to L-ascorbic acid (BP 2

1165 GO:0045603 positive regulation of endotheli 21280 GO:0042921 glucocorticoid receptor signal 21385 GO:0043149 stress fiber assembly (BP) 21513 GO:0032228 regulation of synaptic transmi 21681 GO:0000090 mitotic anaphase (BP) 21685 GO:0035067 negative regulation of histone 21737 GO:0050773 regulation of dendrite develo 2

28 GO:0051925 regulation of calcium ion trans 3210 GO:0000375 RNA splicing, via transesterific 3432 GO:0046326 positive regulation of glucose 3470 GO:0040014 regulation of multicellular or 3806 GO:0042326 negative regulation of phospho 3926 GO:0035094 response to nicotine (BP) 3

84 GO:0001701 in utero embryonic developme 8268 GO:0007519 skeletal muscle tissue develo 4319 GO:0045665 negative regulation of neuron d 4865 GO:0042475 odontogenesis of dentin-conta 4380 GO:0015992 proton transport (BP) 4

54 GO:0043280 positive regulation of cysteine 3399 GO:0033209 tumor necrosis factor-mediate 3

47 GO:0006265 DNA topological change (BP) 2497 GO:0043116 negative regulation of vascular 2724 GO:0016601 Rac protein signal transduction 2729 GO:0007617 mating behavior (BP) 2955 GO:0061029 eyelid development in camera- 2

1007 GO:0048488 synaptic vesicle endocytosis (B 21086 GO:0090399 replicative senescence (BP) 21313 GO:0001953 negative regulation of cell-mat 21465 GO:0042770 signal transduction in respon 21508 GO:0030330 DNA damage response, signal t 21530 GO:0031333 negative regulation of protein 21534 GO:0006983 ER overload response (BP) 21597 GO:0032026 response to magnesium ion (B 21674 GO:0006119 oxidative phosphorylation (BP) 21713 GO:0001921 positive regulation of receptor 2

314 GO:0071260 cellular response to mechanica 4369 GO:0006521 regulation of cellular amino ac 4

1193 GO:0043161 proteasomal ubiquitin-depende 41057 GO:0043154 negative regulation of cystein 4

68 GO:0032956 regulation of actin cytoskeleto 3596 GO:0048812 neuron projection morphogene 3237 GO:0030182 neuron differentiation (BP) 5396 GO:0001934 positive regulation of protein 5436 GO:0043433 negative regulation of sequence 4

39 GO:0007213 G-protein coupled acetylcholin 2

657 GO:0006895 Golgi to endosome transport ( 21015 GO:0048599 oocyte development (BP) 21079 GO:0046902 regulation of mitochondrial m 21232 GO:0043923 positive regulation by host of v 21247 GO:0033365 protein localization to organell 21285 GO:0072659 protein localization in plasm 21355 GO:0006513 protein monoubiquitination (B 21398 GO:0046685 response to arsenic-containing 21608 GO:0042273 ribosomal large subunit biogen 21675 GO:0045176 apical protein localization (BP) 2

70 GO:0008284 positive regulation of cell prol 12418 GO:0030030 cell projection organization (B 4823 GO:0034613 cellular protein localization (B 3

1083 GO:0032321 positive regulation of Rho GTPa 3135 GO:0000910 cytokinesis (BP) 4429 GO:0006370 mRNA capping (BP) 3978 GO:0006605 protein targeting (BP) 3

41 GO:2000426 negative regulation of apoptoti 145 GO:0001773 myeloid dendritic cell activatio 1

393 GO:0031662 positive regulation of cyclin-d 1395 GO:0070194 synaptonemal complex disasse 1621 GO:0035606 peptidyl-cysteine S-trans-nitro 1737 GO:0022605 oogenesis stage (BP) 1

1225 GO:0035522 monoubiquitinated histone H2A 11248 GO:0035726 common myeloid progenitor cell 11254 GO:0071638 negative regulation of monocy 11258 GO:0035732 nitric oxide storage (BP) 11261 GO:0070664 negative regulation of leukocyt 11338 GO:0072362 regulation of glycolysis by ne 11341 GO:2000191 regulation of fatty acid transpo 11343 GO:0072368 regulation of lipid transport 11452 GO:0001973 adenosine receptor signaling 11500 GO:2000300 regulation of synaptic vesicle 11561 GO:0021785 branchiomotor neuron axon gu 11590 GO:0090361 regulation of platelet-derived 11594 GO:0031947 negative regulation of glucocor 11595 GO:0045989 positive regulation of striated 11616 GO:0048243 norepinephrine secretion (BP) 11629 GO:0006669 sphinganine-1-phosphate biosy 11635 GO:0043418 homocysteine catabolic proces 11636 GO:0019343 cysteine biosynthetic process v 11639 GO:0019346 transsulfuration (BP) 11641 GO:0006535 cysteine biosynthetic process 11666 GO:0006086 acetyl-CoA biosynthetic proces 11667 GO:0051068 dihydrolipoamide metabolic pr 11668 GO:0009106 lipoate metabolic process (BP) 11680 GO:0000093 mitotic telophase (BP) 11688 GO:0046146 tetrahydrobiopterin metabolic 1

1689 GO:0006558 L-phenylalanine metabolic pro 11690 GO:0006571 tyrosine biosynthetic process 11705 GO:0032769 negative regulation of monooxy 11706 GO:0010517 regulation of phospholipase act 11707 GO:0050812 regulation of acyl-CoA biosynt 11708 GO:0006638 neutral lipid metabolic process 11711 GO:0070495 negative regulation of thrombi 11712 GO:0051585 negative regulation of dopami 11716 GO:0051622 negative regulation of norepin 11720 GO:2000706 negative regulation of dense c 11721 GO:2000740 negative regulation of mesench 11722 GO:2000798 negative regulation of amniotic 11728 GO:0010232 vascular transport (BP) 11738 GO:0071622 regulation of granulocyte chem 11741 GO:0034047 regulation of protein phosphat 11759 GO:0032222 regulation of synaptic transmis 11760 GO:0002030 inhibitory G-protein coupled r 11764 GO:0015728 mevalonate transport (BP) 11770 GO:0006781 succinyl-CoA pathway (BP) 11777 GO:0009134 nucleoside diphosphate catabol 11779 GO:2001047 regulation of G1/S transition c 11780 GO:0060709 glycogen cell development inv 11787 GO:0042264 peptidyl-aspartic acid hydroxyl 11790 GO:0060440 trachea formation (BP) 11793 GO:0035112 genitalia morphogenesis (BP) 11794 GO:0060479 lung cell differentiation (BP) 11795 GO:0001711 endodermal cell fate commitm 11798 GO:0048262 determination of dorsal/ventr 11807 GO:0014057 positive regulation of acetylch 11812 GO:0031946 regulation of glucocorticoid bi 11813 GO:0043402 glucocorticoid mediated signa 11814 GO:0090044 positive regulation of tubulin 11816 GO:0018272 protein-pyridoxal-5-phosphate 11822 GO:0090149 membrane fission involved in m 11823 GO:0003374 dynamin polymerization involve 11831 GO:0050975 sensory perception of touch (B 11832 GO:0031630 regulation of synaptic vesicle 11833 GO:0048790 maintenance of presynaptic act 11836 GO:0070972 protein localization in endopla 11841 GO:0051252 regulation of RNA metabolic pr 11848 GO:0051046 regulation of secretion (BP) 11855 GO:0031161 phosphatidylinositol catabolic 11859 GO:0048669 collateral sprouting in absence 11861 GO:2000677 regulation of transcription re 11862 GO:0032075 positive regulation of nuclease 11863 GO:0032960 regulation of inositol trisphos 11864 GO:0010758 regulation of macrophage chem 11865 GO:2000058 regulation of protein ubiquitin 1

1866 GO:0042976 activation of Janus kinase activ 11867 GO:0090273 regulation of somatostatin sec 11872 GO:0052547 regulation of peptidase activit 11874 GO:0060405 regulation of penile erection ( 11877 GO:0002866 positive regulation of acute i 11882 GO:0050865 regulation of cell activation (B 11883 GO:0042659 regulation of cell fate specifica 11884 GO:0048305 immunoglobulin secretion (BP) 11888 GO:0006713 glucocorticoid catabolic proces 11891 GO:0072303 positive regulation of glomerul 11893 GO:0072110 glomerular mesangial cell proli 11894 GO:0033233 regulation of protein sumoylat 11895 GO:0048753 pigment granule organization 11896 GO:0032848 negative regulation of cellular 11897 GO:0006582 melanin metabolic process (BP 11898 GO:0014031 mesenchymal cell development 11899 GO:0021747 cochlear nucleus development 11900 GO:0048087 positive regulation of develop 11901 GO:0014042 positive regulation of neuron 11902 GO:0043375 CD8-positive, alpha-beta T cel 11904 GO:0006808 regulation of nitrogen utilizati 11905 GO:0034401 regulation of transcription by 11906 GO:0006109 regulation of carbohydrate met 11907 GO:0032095 regulation of response to food 11908 GO:0043610 regulation of carbohydrate util 11912 GO:0021902 commitment of neuronal cell to 11913 GO:0021905 forebrain-midbrain boundary f 11914 GO:0021918 regulation of transcription f 11915 GO:0003322 pancreatic A cell development 11916 GO:0051580 regulation of neurotransmitter 11917 GO:0010625 positive regulation of Schwann 11918 GO:0015866 ADP transport (BP) 11920 GO:0060359 response to ammonium ion (B 11921 GO:0072365 regulation of cellular ketone 11922 GO:0030683 evasion by virus of host immu 11925 GO:0046670 positive regulation of retinal 11926 GO:0002525 acute inflammatory response t 11927 GO:0045556 positive regulation of TRAIL bi 11928 GO:0032011 ARF protein signal transductio 11929 GO:2000655 negative regulation of cellular 11930 GO:2000480 negative regulation of cAMP-de 11931 GO:0006343 establishment of chromatin sil 11932 GO:2000757 negative regulation of peptidyl 11933 GO:0034391 regulation of smooth muscle ce 11934 GO:0031937 positive regulation of chromati 11935 GO:0031393 negative regulation of prostag 11936 GO:0045083 negative regulation of interleu 11937 GO:0019242 methylglyoxal biosynthetic pro 1

1938 GO:0070294 renal sodium ion absorption (B 11939 GO:0060453 regulation of gastric acid secre 11940 GO:0051660 establishment of centrosome lo 11941 GO:0021540 corpus callosum morphogenesi 11942 GO:0046469 platelet activating factor meta 1

146 GO:0010226 response to lithium ion (BP) 2158 GO:0048208 COPII vesicle coating (BP) 2305 GO:0060134 prepulse inhibition (BP) 2506 GO:0042274 ribosomal small subunit biogen 2852 GO:0032886 regulation of microtubule-base 2856 GO:0071108 protein K48-linked deubiquitin 2863 GO:0051085 chaperone mediated protein fol 2953 GO:0032922 circadian regulation of gene e 2979 GO:0051968 positive regulation of synaptic 2

1103 GO:0030431 sleep (BP) 21113 GO:0048738 cardiac muscle tissue develop 21241 GO:0046209 nitric oxide metabolic process 21532 GO:0031334 positive regulation of protein 2

115 GO:0043627 response to estrogen stimulus 4231 GO:0034138 toll-like receptor 3 signaling 4363 GO:0034641 cellular nitrogen compound me 8337 GO:0070830 tight junction assembly (BP) 3631 GO:0006749 glutathione metabolic process 3728 GO:0016485 protein processing (BP) 3469 GO:0032355 response to estradiol stimulus 5538 GO:0006383 transcription from RNA polyme 3969 GO:0007613 memory (BP) 3

1146 GO:0045727 positive regulation of translati 3227 GO:0045885 positive regulation of survival 2573 GO:0045725 positive regulation of glycogen 2682 GO:0051493 regulation of cytoskeleton org 2882 GO:0031529 ruffle organization (BP) 2944 GO:0048205 COPI coating of Golgi vesicle ( 2

1373 GO:0008637 apoptotic mitochondrial chang 21406 GO:0030833 regulation of actin filament po 2

132 GO:0034220 ion transmembrane transport 5507 GO:0006364 rRNA processing (BP) 5

List size Reference Support Reference size Hyp518 215 34208 2.04E-23518 594 34208 1.08E-22518 329 34208 1.67E-18518 328 34208 1.51E-18518 1176 34208 3.66E-15518 205 34208 1.07E-13518 341 34208 9.23E-14518 457 34208 1.83E-13518 150 34208 1.65E-13518 383 34208 2.94E-13518 578 34208 1.15E-12518 408 34208 1.49E-12518 76 34208 8.16E-12518 307 34208 1.24E-11518 128 34208 1.17E-11518 192 34208 1.73E-11518 53 34208 1.95E-11518 98 34208 2.38E-11518 156 34208 3.22E-11518 86 34208 4.69E-11518 257 34208 8.15E-11518 110 34208 1.30E-10518 290 34208 1.40E-10518 49 34208 1.50E-10518 223 34208 2.59E-10518 272 34208 2.43E-10518 155 34208 2.54E-10518 604 34208 3.14E-10518 312 34208 5.90E-10518 401 34208 7.13E-10518 410 34208 1.14E-09518 413 34208 1.33E-09518 151 34208 1.43E-09518 301 34208 1.64E-09518 304 34208 1.97E-09518 62 34208 2.19E-09518 196 34208 9.45E-09518 224 34208 1.16E-08518 200 34208 1.28E-08518 43 34208 1.39E-08518 21 34208 1.70E-08518 468 34208 1.75E-08518 182 34208 2.13E-08518 95 34208 2.24E-08518 185 34208 2.68E-08518 61 34208 2.63E-08

518 33 34208 2.61E-08518 139 34208 2.92E-08518 36 34208 5.46E-08518 172 34208 6.52E-08518 37 34208 6.88E-08518 106 34208 7.77E-08518 178 34208 1.03E-07518 39 34208 1.07E-07518 1609 34208 1.15E-07518 234 34208 1.28E-07518 40 34208 1.32E-07518 416 34208 1.28E-07518 17 34208 1.26E-07518 294 34208 1.48E-07518 74 34208 1.75E-07518 114 34208 1.75E-07518 115 34208 1.92E-07518 30 34208 2.64E-07518 284 34208 4.19E-07518 102 34208 4.45E-07518 82 34208 4.69E-07518 128 34208 6.20E-07518 129 34208 6.74E-07518 49 34208 6.85E-07518 67 34208 7.66E-07518 241 34208 9.96E-07518 89 34208 1.01E-06518 73 34208 1.61E-06518 7 34208 1.75E-06518 167 34208 1.78E-06518 41 34208 2.52E-06518 42 34208 2.99E-06518 42 34208 2.99E-06518 16 34208 2.97E-06518 28 34208 3.32E-06518 8 34208 3.47E-06518 43 34208 3.52E-06518 3 34208 3.45E-06518 3 34208 3.45E-06518 543 34208 3.65E-06518 30 34208 5.11E-06518 131 34208 5.35E-06518 31 34208 6.25E-06518 67 34208 7.80E-06518 91 34208 1.02E-05518 10 34208 1.02E-05518 10 34208 1.02E-05518 140 34208 1.01E-05

518 92 34208 1.11E-05518 51 34208 1.14E-05518 93 34208 1.22E-05518 52 34208 1.30E-05518 398 34208 1.29E-05518 630 34208 1.46E-05518 11 34208 1.58E-05518 22 34208 1.66E-05518 75 34208 1.82E-05518 520 34208 1.81E-05518 179 34208 2.02E-05518 57 34208 2.41E-05518 40 34208 2.90E-05518 5 34208 3.37E-05518 5 34208 3.37E-05518 5 34208 3.37E-05518 41 34208 3.36E-05518 13 34208 3.33E-05518 13 34208 3.33E-05518 13 34208 3.33E-05518 82 34208 3.50E-05518 107 34208 3.77E-05518 14 34208 4.61E-05518 14 34208 4.61E-05518 27 34208 4.79E-05518 111 34208 5.03E-05518 64 34208 5.17E-05518 112 34208 5.40E-05518 87 34208 5.37E-05518 230 34208 5.52E-05518 15 34208 6.21E-05518 15 34208 6.21E-05518 66 34208 6.31E-05518 267 34208 6.51E-05518 6 34208 6.67E-05518 29 34208 6.87E-05518 29 34208 6.87E-05518 90 34208 6.85E-05518 30 34208 8.14E-05518 30 34208 8.14E-05518 30 34208 8.14E-05518 70 34208 9.22E-05518 312 34208 9.58E-05518 49 34208 9.43E-05518 31 34208 9.58E-05518 31 34208 9.58E-05518 121 34208 9.85E-05518 96 34208 0.000108236

518 7 34208 0.000115475518 7 34208 0.000115475518 7 34208 0.000115475518 7 34208 0.000115475518 7 34208 0.000115475518 32 34208 0.00011218518 18 34208 0.000134357518 75 34208 0.000143107518 75 34208 0.000143107518 34 34208 0.000151194518 34 34208 0.000151194518 34 34208 0.000151194518 129 34208 0.000160653518 54 34208 0.000163409518 19 34208 0.000168154518 35 34208 0.000174211518 78 34208 0.00018321518 8 34208 0.000182679518 8 34208 0.000182679518 8 34208 0.000182679518 8 34208 0.000182679518 56 34208 0.000200256518 56 34208 0.000200256518 105 34208 0.000202192518 20 34208 0.000207684518 20 34208 0.000207684518 2 34208 0.000228864518 2 34208 0.000228864518 2 34208 0.000228864518 2 34208 0.000228864518 2 34208 0.000228864518 2 34208 0.000228864518 2 34208 0.000228864518 2 34208 0.000228864518 2 34208 0.000228864518 2 34208 0.000228864518 2 34208 0.000228864518 2 34208 0.000228864518 80 34208 0.000214658518 57 34208 0.000220981518 21 34208 0.000253491518 21 34208 0.000253491518 38 34208 0.000259495518 9 34208 0.000270936518 9 34208 0.000270936518 22 34208 0.000306129518 22 34208 0.000306129518 175 34208 0.000359208

518 23 34208 0.000366162518 145 34208 0.000384345518 10 34208 0.000382701518 10 34208 0.000382701518 10 34208 0.000382701518 10 34208 0.000382701518 10 34208 0.000382701518 10 34208 0.000382701518 41 34208 0.000373249518 435 34208 0.000398031518 90 34208 0.000443538518 148 34208 0.000446469518 65 34208 0.000454303518 65 34208 0.000454303518 150 34208 0.000492297518 11 34208 0.000520302518 11 34208 0.000520302518 11 34208 0.000520302518 153 34208 0.000568223518 68 34208 0.000579489518 45 34208 0.000579048518 95 34208 0.000614931518 12 34208 0.000685949518 12 34208 0.000685949518 12 34208 0.000685949518 12 34208 0.000685949518 27 34208 0.000691776518 3 34208 0.000679687518 3 34208 0.000679687518 3 34208 0.000679687518 3 34208 0.000679687518 3 34208 0.000679687518 3 34208 0.000679687518 3 34208 0.000679687518 3 34208 0.000679687518 3 34208 0.000679687518 71 34208 0.000729922518 13 34208 0.000881732518 13 34208 0.000881732518 13 34208 0.000881732518 13 34208 0.000881732518 13 34208 0.000881732518 13 34208 0.000881732518 49 34208 0.00086006518 29 34208 0.00091409518 29 34208 0.00091409518 74 34208 0.000908888518 50 34208 0.000943866

518 309 34208 0.00095952518 30 34208 0.0010422518 30 34208 0.0010422518 51 34208 0.00103359518 105 34208 0.00111329518 105 34208 0.00111329518 77 34208 0.00111985518 14 34208 0.00110963518 14 34208 0.00110963518 31 34208 0.0011824518 78 34208 0.0011979518 4 34208 0.00134572518 4 34208 0.00134572518 4 34208 0.00134572518 4 34208 0.00134572518 4 34208 0.00134572518 4 34208 0.00134572518 4 34208 0.00134572518 4 34208 0.00134572518 4 34208 0.00134572518 4 34208 0.00134572518 4 34208 0.00134572518 4 34208 0.00134572518 15 34208 0.0013715518 15 34208 0.0013715518 15 34208 0.0013715518 79 34208 0.00128005518 32 34208 0.00133529518 32 34208 0.00133529518 54 34208 0.00134084518 285 34208 0.00147463518 16 34208 0.00166911518 16 34208 0.00166911518 16 34208 0.00166911518 16 34208 0.00166911518 16 34208 0.00166911518 34 34208 0.00168149518 34 34208 0.00168149518 113 34208 0.00170414518 58 34208 0.00184911518 85 34208 0.00186689518 35 34208 0.00187598518 17 34208 0.00200411518 17 34208 0.00200411518 36 34208 0.0020855518 36 34208 0.0020855518 36 34208 0.0020855518 87 34208 0.00210179

518 5 34208 0.00222037518 5 34208 0.00222037518 5 34208 0.00222037518 5 34208 0.00222037518 5 34208 0.00222037518 5 34208 0.00222037518 5 34208 0.00222037518 5 34208 0.00222037518 5 34208 0.00222037518 5 34208 0.00222037518 37 34208 0.00231063518 556 34208 0.00229827518 187 34208 0.00230884518 18 34208 0.00237806518 18 34208 0.00237806518 18 34208 0.00237806518 18 34208 0.00237806518 39 34208 0.00280999518 39 34208 0.00280999518 19 34208 0.00279242518 19 34208 0.00279242518 19 34208 0.00279242518 19 34208 0.00279242518 19 34208 0.00279242518 92 34208 0.00278642518 6 34208 0.00329718518 6 34208 0.00329718518 6 34208 0.00329718518 6 34208 0.00329718518 6 34208 0.00329718518 6 34208 0.00329718518 6 34208 0.00329718518 6 34208 0.00329718518 6 34208 0.00329718518 6 34208 0.00329718518 6 34208 0.00329718518 6 34208 0.00329718518 6 34208 0.00329718518 6 34208 0.00329718518 6 34208 0.00329718518 6 34208 0.00329718518 6 34208 0.00329718518 6 34208 0.00329718518 6 34208 0.00329718518 65 34208 0.00305787518 94 34208 0.00310248518 41 34208 0.00337854518 20 34208 0.00324855

518 20 34208 0.00324855518 20 34208 0.00324855518 20 34208 0.00324855518 95 34208 0.00327018518 21 34208 0.00374773518 21 34208 0.00374773518 21 34208 0.00374773518 21 34208 0.00374773518 21 34208 0.00374773518 21 34208 0.00374773518 42 34208 0.00369013518 42 34208 0.00369013518 43 34208 0.00402064518 43 34208 0.00402064518 22 34208 0.00429114518 7 34208 0.00456987518 7 34208 0.00456987518 7 34208 0.00456987518 7 34208 0.00456987518 7 34208 0.00456987518 7 34208 0.00456987518 7 34208 0.00456987518 7 34208 0.00456987518 7 34208 0.00456987518 7 34208 0.00456987518 7 34208 0.00456987518 71 34208 0.0044775518 45 34208 0.00474049518 23 34208 0.00487989518 23 34208 0.00487989518 23 34208 0.00487989518 23 34208 0.00487989518 23 34208 0.00487989518 46 34208 0.00513086518 46 34208 0.00513086518 74 34208 0.00533963518 24 34208 0.00551499518 24 34208 0.00551499518 24 34208 0.00551499518 24 34208 0.00551499518 24 34208 0.00551499518 24 34208 0.00551499518 24 34208 0.00551499518 106 34208 0.00558971518 106 34208 0.00558971518 75 34208 0.00565136518 8 34208 0.00603226518 8 34208 0.00603226

518 8 34208 0.00603226518 8 34208 0.00603226518 8 34208 0.00603226518 8 34208 0.00603226518 8 34208 0.00603226518 8 34208 0.00603226518 8 34208 0.00603226518 8 34208 0.00603226518 8 34208 0.00603226518 8 34208 0.00603226518 25 34208 0.00619739518 25 34208 0.00619739518 25 34208 0.00619739518 25 34208 0.00619739518 25 34208 0.00619739518 25 34208 0.00619739518 179 34208 0.00616358518 48 34208 0.00597492518 48 34208 0.00597492518 48 34208 0.00597492518 50 34208 0.0069066518 27 34208 0.00770748518 27 34208 0.00770748518 9 34208 0.00767836518 9 34208 0.00767836518 9 34208 0.00767836518 9 34208 0.00767836518 9 34208 0.00767836518 9 34208 0.00767836518 9 34208 0.00767836518 9 34208 0.00767836518 9 34208 0.00767836518 9 34208 0.00767836518 9 34208 0.00767836518 9 34208 0.00767836518 9 34208 0.00767836518 9 34208 0.00767836518 9 34208 0.00767836518 51 34208 0.00740643518 51 34208 0.00740643518 52 34208 0.0079295518 53 34208 0.00847625518 28 34208 0.00853668518 28 34208 0.00853668518 84 34208 0.0090552518 84 34208 0.0090552518 54 34208 0.00904709518 10 34208 0.00950227

518 10 34208 0.00950227518 10 34208 0.00950227518 10 34208 0.00950227518 10 34208 0.00950227518 10 34208 0.00950227518 10 34208 0.00950227518 10 34208 0.00950227518 10 34208 0.00950227518 10 34208 0.00950227518 10 34208 0.00950227518 361 34208 0.00956069518 55 34208 0.0096424518 29 34208 0.00941621518 29 34208 0.00941621518 56 34208 0.0102626518 30 34208 0.0103467518 30 34208 0.0103467518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427

518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427

518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 1 34208 0.0151427518 11 34208 0.0114983518 11 34208 0.0114983518 11 34208 0.0114983518 11 34208 0.0114983518 11 34208 0.0114983518 11 34208 0.0114983518 11 34208 0.0114983518 11 34208 0.0114983518 11 34208 0.0114983518 11 34208 0.0114983518 11 34208 0.0114983518 11 34208 0.0114983518 11 34208 0.0114983518 63 34208 0.0153299518 63 34208 0.0153299518 200 34208 0.0116119518 31 34208 0.0113285518 31 34208 0.0113285518 31 34208 0.0113285518 89 34208 0.0114548518 35 34208 0.0157788518 35 34208 0.0157788518 35 34208 0.0157788518 13 34208 0.0159842518 13 34208 0.0159842518 13 34208 0.0159842518 13 34208 0.0159842518 13 34208 0.0159842518 13 34208 0.0159842518 13 34208 0.0159842518 97 34208 0.016137518 90 34208 0.0119819

Hyp_c Genes3.97E-20 ELK1,GRB2,CASP2,NFKB1,AP2A2,MAPK1,YWHAE,ZFYVE27,HDAC3,MTOR,TRIO,TRAF6,NGFR,MAGED1,PIK3R1,HDAC2,ITPR1,ADORA2A,AKT1,HDAC1,PDE1B,CLTC,TSC2,YWHAB,GSK3B,AP2B1,RAC1,ARHGEF6,RAPGEF1,ARHGEF7,SQSTM1,AP2A1,CASP31.05E-19 HIP1,CASP2,NFKB1,CASP6,PPM1F,PSMC2,TJP2,API5,YWHAE,NCKAP1,ADD1,TRIO,BCL2,TRAF6,NGFR,PTK2B,HMGB2,MAGED1,TP53,MEF2D,PSMD8,DNM1L,FNTA,ADORA2A,CTNNB1,AKT1,PDE1B,PPP1R13B,HTT,GJA1,APAF1,UBQLN1,PSMA1,NISCH,CUL1,CYFIP2,YWHAB,CASP1,TP53INP1,RAC1,ARHGEF6,CASP7,NDUFS1,GSN,ARHGEF7,SQSTM1,VDAC1,CASP3,PSMD3,HMGB18.09E-16 XRCC6,AP2A2,PSMC2,SLC25A4,SSRP1,RPL7,RPL23,RPL15,RPL14,RPL13,RNGTT,RANBP2,TAF4,PSMD8,NUP98,AP1B1,AP1G1,SUPT5H,TAF4B,TPR,NUP160,PSMA1,TBP,AP2B1,RAC1,NUP62,RPL6,ZNF24,RPLP2,NUP153,AP2A1,RPS6,RNMT,PSMD39.81E-16 GRB2,SP1,UBR4,VPRBP,SIRT1,PSMC2,MAPK1,EIF2AK2,SLC25A4,NEDD4L,YWHAE,CTBP1,DDB1,CAV1,RNGTT,NACA,SRCAP,TP53,CUL2,TAF4,PIK3R1,DYNC1I2,HSPA8,NUP98,HDAC1,KAT2B,SF3B2,CUL1,USP7,TBP,FBLN1,VDAC1,NUP153,CREBBP1.42E-12 FLNB,PPP2R2A,NFKB1,SRGAP1,TNFRSF8,MAPK1,GRIN2A,RASD2,SRGAP2,DPYSL2,MAP3K10,DNM2,MTOR,TRAF6,BAIAP2,ARHGAP18,TNFSF13B,NGFR,PTK2B,SNX27,ZDHHC17,YWHAZ,MLLT4,CREBL2,RASA1,VAPA,PRKAA2,PIK3R1,RAP1B,CORO1C,ITPR1,NR3C1,AKT1,TRIP10,PDE1B,GNB1,CAMK2B,PI4KA,PPM1A,GJA1,TRAF1,TSC2,EGFR,EPS8,TRAF3,ARHGAP1,NDRG2,DLG4,CASP1,RAPGEF1,INPP5B,GNAI2,SH3GL3,ARHGEF7,CREBBP,ATM,OGT,PPP1R16B2.97E-11 SGK1,HIP1,CASP2,SIRT1,PSMC2,BTG1,BCL2,TRAF6,DUSP2,MAGED1,TP53,PSMD8,CAMK1D,APAF1,TRAF1,PSMA1,TRAF3,CASP1,ACTN1,CASP3,CASP8,Casp10,PSMD32.99E-11 TNFRSF8,EIF2AK2,BTG1,BCL11B,CTBP1,CSK,CAV1,GDF11,PTK2B,PRKRA,WDR6,TP53,CUL2,RBM5,CTH,ADORA2A,CTNNB1,ASPH,KAT2B,GJA1,REST,CDH13,FABP3,INPPL1,TSC2,CUL1,NUP62,BECN1,BAP13.96E-11 GRB2,MAPK1,SIN3A,ATP2A2,CSK,CAPZA1,CAV1,CABLES1,APP,YWHAZ,TP53,PIK3R1,RAP1B,ALDOA,HDAC2,ITPR1,ADORA2A,AKT1,CAPZB,HDAC1,PDE1B,SLC16A1,GNB1,CALU,RAD51C,PPIL2,CAPZA2,RAC1,ACTN1,ATP1B1,GNAI2,TLN1,ENTPD14.00E-11 PARK2,UBE2K,PSMC2,Ube3a,USP19,UBE2D2,CUL2,USP14,USP21,USP9X,PSMA1,USP1,CUL1,USP7,USP8,UCHL3,UBE2H,BAP1,SQSTM1,USP405.71E-11 PAFAH1B1,SYN1,AP2A2,NSF,MAPK1,GRIN2A,EPB41L1,VAMP2,MBP,SYT1,CACNA1E,MYO6,CAMK2G,USP14,RAB3A,GRIN1,HSPA8,STXBP1,GNB1,CAMK2B,PI4KA,KCNN3,DLG4,SNAP91,AP2B1,STX1A,GNAI2,KCNC1,SNAP25,AP2A12.04E-10 ELK1,TFEB,SP1,XRCC6,ZNF292,SREBF2,NFKB1,SIRT1,Ube3a,PAX6,BCL11B,NFYA,EGR1,TRAF6,LMO4,BAG1,HMGB2,CHD8,APP,MYO6,SMARCA4,TP53,MEF2D,PIK3R1,GRIN1,HDAC2,SUPT5H,CTNNB1,AKT1,HDAC1,KAT2B,CBFA2T2,ARNTL,SQSTM1,CREBBP,HMGB12.41E-10 SF3A3,MED15,SSRP1,RPL7,RPL23,RPL15,RPL14,RPL13,PRPF8,SNRNP200,RNGTT,SF3B3,EEF1A1,TAF4,RBM5,NR3C1,SUPT5H,TAF4B,MED23,SNW1,KAT2B,SF3B2,TBP,EFTUD2,RPL6,YBX1,RPLP2,CREBBP,RPS6,RNMT1.22E-09 GRB2,AP2A2,MAPK1,ARF4,CSK,PTK2B,PIK3R1,CLTC,EGFR,EPS8,YWHAB,AP2B1,ARHGEF7,AP2A11.61E-09 GRB2,COL4A5,AP2A2,SRGAP1,FEZ1,MAPK1,SRGAP2,PAX6,EZR,DPYSL2,MYH10,TRIO,NGFR,STIP1,CNTN1,CLTC,EGFR,YWHAB,DLG4,MYL6,GSK3B,AP2B1,RAC1,TLN1,AP2A11.62E-09 PAFAH1B1,FLNB,FMNL3,MYH10,ADD1,CAPZA1,DIAPH1,ARPC1A,CORO1C,TRIP10,CAPZB,ADD2,FHOD3,NISCH,CAPZA2,PFN2,CORO1B2.10E-09 SEC16A,SEC24C,AP2A2,NSF,VAMP2,ARF4,AP3D1,ARFGAP1,RAB11A,AP1B1,AP1G1,STXBP1,RAB14,CLTC,GGA3,TSC2,AP2B1,SEC23A,STX1A,GSN2.22E-09 SYN1,VAMP2,SYT1,RAB3A,HSPA8,PPFIA3,STXBP1,RAB14,SNAP91,AP2B1,STX1A,SNAP252.57E-09 GPI,PFKM,FABP5,PIK3R1,ALDOA,AKT1,SLC25A11,INPPL1,SLC25A12,PGM1,NISCH,GOT1,SLC25A13,UGP2,GAPDH3.29E-09 PARK2,HIP1,CTSD,ZFYVE27,BCL2,SPG7,SPG20,UBA1,APP,VAPA,ITPR1,HTT,DCTN1,SNCA,UBQLN2,TBP,NUP62,ATM4.56E-09 NDUFV1,ATP5B,COX4I1,UQCRC2,NDUFV2,COX6C,ATP5C1,ATP5F1,NDUFS3,ATP5A1,NDUFS1,NDUFB10,NDUFA8,NDUFB87.54E-09 PPP2R2A,EDC4,PSMC2,DDX24,RPL7,RPL23,RPL15,RPL14,RPL13,YWHAZ,HSPA8,PSMD8,SMG5,AKT1,BZW2,PSMA1,YWHAB,RPL6,RPLP2,UPF1,RPS6,PSMD31.15E-08 HIP1,AP2A2,DNM2,PACSIN1,APP,MYO6,AP1B1,AP1G1,FNBP1,TRIP10,DNM1,INPPL1,TSC2,SH3GL3,AP2A11.18E-08 GPI,PPP1CA,PFKM,SLC2A3,B4GALT6,RANBP2,NUP98,ALDOA,AKT1,SLC25A11,TPR,NUP160,SLC25A12,PGM1,GOT1,PPP1R3D,GSK3B,NUP62,MGAT1,NUP153,SLC25A13,UGP2,GAPDH1.21E-08 CASP6,TJP2,ADD1,HMGB2,DNM1L,FNTA,CTNNB1,CASP7,GSN,CASP3,HMGB11.86E-08 PPP2R2A,EDC4,PSMC2,RPL7,RPL23,RPL15,RPL14,RPL13,YWHAZ,HSPA8,PSMD8,SMG5,AKT1,PSMA1,YWHAB,RPL6,RPLP2,UPF1,RPS6,PSMD31.88E-08 SIRT1,BCL11B,SIN3A,BCL2,ADAR,PTK2B,CHD8,TP53,PRKAA2,PIK3R1,HDAC2,CTNNB1,AKT1,HDAC1,EGFR,ASNS,GSK3B,NUP62,GSTP1,ATM,CASP3,RPS61.90E-08 SGK1,MAPK1,CNR1,BAG1,PTK2B,DNAJB1,PRKRA,STIP1,TRAP1,PRKAA2,HSPA8,FADS1,HSPA4,EGFR,TP53INP1,SQSTM1,HSPA22.18E-08 PAFAH1B1,NDUFV1,SYN1,DYNC1H1,SLC25A3,ATP5B,FEZ1,GRIN2A,SLC25A4,SLC35F5,ATP2A2,UQCRC2,G3BP2,HDLBP,NDUFV2,CACNA1E,DYNC1I2,FADS1,AKT1,NDUFS3,SLC25A11,GJA1,CPT1B,CPT2,SORBS1,ATP6V0E1,ATP1B1,NDUFS1,NDUFB10,CTNS,NDUFA8,NDUFB8,SLC25A133.95E-08 SRGAP1,MYO9B,MAPK1,RASD2,SRGAP2,TRIO,ARHGAP18,ARF4,G3BP2,RAB10,RAB28,RAB3A,RAP1B,RAB11A,TRIP10,RAB14,ARHGAP1,YWHAB,RAC1,ARHGEF6,INPP5B,ARHGEF7,ARL24.62E-08 MECP2,XRCC6,NFKB1,SIRT1,SIN3A,MAP3K10,HDAC3,CTBP1,TRAF6,HMGB2,CHD8,SMARCA4,TP53,HSPA8,HDAC2,CTNNB1,HDAC1,SNW1,REST,SUMO1,SIN3B,YWHAB,CBFA2T2,YBX1,ZNF24,SMARCC27.15E-08 PAFAH1B1,FEZ1,DPYSL2,SPG7,NDUFV2,CABLES1,GDF11,INA,SMARCA4,DBN1,MEF2D,CAMK2G,FNBP1,AKT1,CAMK2B,BZW2,CAMK1D,DCTN1,APAF1,NDRG2,DLG4,GSK3B,TMOD2,ARHGEF7,SMARCC2,GSS8.07E-08 SEC16A,NSF,COG1,ARF4,RAB10,SNX25,SNX27,ARFGAP1,NACA,VPS39,RANBP2,RAB3A,RAB11A,NUP98,STXBP1,RAB14,VPS54,TPR,CHCHD4,NUP160,SEC61A2,NUP62,SLC15A4,NXT2,VPS35,NUP1538.40E-08 RASD2,GNAZ,DNM2,ARF4,GSPT1,RAB28,RAB3A,RAP1B,RAB11A,GNB1,DNM1,RAB14,RAC1,EFTUD2,GNAI2,ARL29.36E-08 SREBF2,GRIN2A,DPYSL2,HDAC3,BCL2,BAG1,CAV1,PTK2B,DRD1,YWHAZ,TP53,PIK3R1,ADD3,ADORA2A,CTNNB1,HADHA,SNCA,FABP3,INPPL1,XPC,ATP1A1,MAT2A1.09E-07 PAFAH1B1,DYNC1H1,PSMC2,TUBB,YWHAE,RANBP2,CEP63,DYNC1I2,PSMD8,CEP250,NUP98,NUMA1,DCTN1,TUBG1,MAD1L1,ANAPC1,NUP160,PSMA1,CUL1,BUB3,YWHAG,PSMD31.18E-07 SIRT1,MTOR,BCL2,EGR1,FADS1,NR3C1,HADHA,FABP3,INPPL1,MAX,OGT4.96E-07 SEC24C,AP2A2,NAPA,YWHAH,AP3D1,DRD1,MYO6,NAPB,TOMM22,AP1B1,AP1G1,CLTC,GGA3,AP2B1,SEC23A,STX1A,AP2A15.91E-07 HDAC3,ASXL1,TRRAP,CABIN1,DOT1L,CHD8,SRCAP,PRKAA2,EP400,USP21,HDAC2,EZH1,NR3C1,HDAC1,CHD3,NCOR1,BAP1,WHSC16.37E-07 NFKB1,API5,HDAC3,BCL2,TRAF6,NGFR,BAG1,YWHAZ,NR3C1,AKT1,HDAC1,HSPA9,SNCA,SPHK2,BECN1,GSTP1,SQSTM16.77E-07 BCL2,TP53,CUL2,AKT1,APAF1,CUL1,YWHAB,CASP7,CASP38.04E-07 GRIN2A,SYP,EGR1,DRD1,CAMK2B,SNCA,DLG48.10E-07 ELK1,SP1,XRCC6,NFKB1,MAPK1,PAX6,ILK,DNM2,EGR1,YWHAH,HMGB2,CHD8,SMARCA4,TP53,TAF4,USP21,HDAC2,CTNNB1,HDAC1,PPM1A,REST,TBP,NUP62,NFYC,CREBBP,SMARCC29.61E-07 DNAJA1,CCT4,CCT2,DNAJC21,DNAJB1,TRAP1,RANBP2,DNAJC1,HSPA8,TBCD,TCP1,PPIB,DNAJA2,HSPA9,PPIL2,NFYC9.90E-07 SEC24C,NAPA,VAMP2,DNM2,ARFGAP1,HSPA8,AP1B1,AP1G1,GJA1,CLTC,GBF1,SEC23A1.11E-06 HIP1,CASP6,MAPK1,MAP3K10,NGFR,PRKRA,APP,TGM2,TP53,NDUFS3,PPP1R13B,TRAF3,USP7,TP53INP1,CASP7,CASP31.11E-06 FABP5,SLC2A3,RANBP2,NUP98,AKT1,TPR,SORBS1,NUP160,NUP62,NUP153

1.13E-06 GRB2,AP2A2,CLTC,EGFR,AP2B1,NUP62,ARHGEF7,AP2A11.18E-06 GRB2,MAPK1,MTOR,BAIAP2,PRKAA2,PIK3R1,AKT1,ATP6V0A1,PPM1A,SORBS1,TSC2,YWHAB,ATP6V0E1,RPS62.17E-06 NDUFV1,NDUFV2,NDUFS3,DLD,NDUFS1,NDUFB10,NDUFA8,NDUFB82.54E-06 SRGAP1,MYO9B,SRGAP2,TRIO,ARHGAP18,G3BP2,RASA1,TRIP10,TSC2,ARHGAP1,RAC1,ARHGEF6,RAPGEF1,INPP5B,ARHGEF72.62E-06 ATP5B,ATP2A2,ALDOA,ATP5C1,ATP1A1,ATP5A1,ATP1B1,SLC25A132.90E-06 CASP2,YWHAE,TRIO,TRAF6,NGFR,CAV1,MAGED1,RAC1,ARHGEF6,ARHGEF7,SQSTM1,CASP33.76E-06 CASP2,SIRT1,TNFRSF8,GRIN2A,DNM2,CNR1,TP53,PIK3R1,RBM5,CTNNB1,REST,ARHGEF7,ATM,RPS6,HMGB13.84E-06 CASP2,CASP6,BAG1,TP53,NR3C1,CASP7,ATM,CASP34.05E-06 TFEB,SP1,HIP1,ZNF292,SFMBT2,NCOR2,BTG1,SSRP1,PAX6,BCL11B,NFYA,DNM2,ZNF207,ASXL1,LMO4,TRRAP,BATF,FLII,POU2AF1,MAGED1,SMARCA4,TP53,CREBL2,EEF1A1,MEF2D,PRKAA2,EP400,DNAJC1,HDAC2,EZH1,FADS1,NR3C1,ADORA2A,TAF4B,MED23,HDAC1,POU3F2,REST,ZFP36L2,CHD3,MAX,MYCBP2,TBP,ZNF91,RPL6,EWSR1,YBX1,PSPC1,NCOR1,NFYC,CREBBP,WHSC1,SMARCC24.28E-06 MAPK1,ATP2A2,APP,YWHAZ,PIK3R1,ENTPD2,ALDOA,ITPR1,AKT1,PDE1B,GNB1,CALU,RAC1,ACTN1,GNAI2,TLN1,ENTPD14.33E-06 NAPA,VAMP2,DNM2,HSPA8,AP1B1,AP1G1,CLTC,GBF14.35E-06 MECP2,NFKB1,SIRT1,NCOR2,HDAC3,CTBP1,EGR1,TRAF6,CAV1,SMARCA4,TP53,HDAC2,EZH1,SUPT5H,CTNNB1,HDAC1,REST,YBX1,NCOR1,ZMYND8,CREBBP,WHSC1,HMGB14.37E-06 VAMP2,SYT1,RAB3A,STXBP1,STX1A,SNAP254.81E-06 NFKB1,SSRP1,PAX6,NFYA,EGR1,LMO4,RNGTT,POU2AF1,MAF,MEF2D,TAF4,NR3C1,SUPT5H,TAF4B,MAX,TBP,YBX1,NCOR1,RNMT5.50E-06 SLC25A4,MARCKS,VAMP2,CNR1,CACNA1E,RAP1B,ITPR1,STXBP1,STX1A,SNAP255.57E-06 GRB2,CASP2,SREBF2,SIN3A,CNR1,FADS1,NR3C1,DLD,HMGCR,CASP7,GSN,GSS5.93E-06 PAFAH1B1,DYNC1H1,TUBB,DNM2,YWHAE,CEP63,DYNC1I2,CEP250,NUMA1,DCTN1,TUBG1,YWHAG8.01E-06 GRIN2A,CACNA1E,APP,DRD1,GRIN1,PDE1B,HMGCR1.25E-05 SEC24C,CCT4,CCT2,RPL7,RPL23,RPL15,RPL14,RPL13,B4GALT6,EEF1A1,TBCD,TCP1,PIGM,SEC23A,RPL6,MGAT1,RPLP2,RPS61.31E-05 SLC25A4,MARCKS,VAMP2,CACNA1E,PRKAA2,RAP1B,ITPR1,STXBP1,GNB1,STX1A,SNAP251.36E-05 MYO9B,PSMC2,ATP5B,ATP2A2,HSPA8,ATP5C1,ATP5F1,ATP1A1,ATP5A1,ENTPD11.77E-05 NCOR2,SIN3A,HDAC3,PRKAA2,FADS1,HADHA,CPT1B,INPPL1,CPT2,SIN3B,NCOR1,CREBBP1.90E-05 ILK,MLF1,WDR6,TP53,CUL2,PRKAA2,KAT2B,PPM1A,TSC2,CUL1,TP53INP1,ATM1.90E-05 ILK,DRD1,ADORA2A,AKT1,THY1,TSC2,GSTP1,YWHAG2.10E-05 MYH10,ZFYVE27,PTK2B,DIAPH1,APP,VAPA,RAB11A,CNTN1,HMGB12.69E-05 EIF2AK2,RPL7,RPL23,RPL15,TNIP1,RPL14,RPL13,MRPS5,NACA,GSPT1,EEF1A1,AKT1,GCN1L1,RPL6,RPLP2,RPS62.70E-05 COX4I1,MTOR,BCL2,CNR1,CAV1,PIK3R1,FADS1,HMGCR,GNAI2,OGT4.22E-05 MTOR,HMGB2,PIK3R1,AKT1,PI4KA,TSC2,GSK3B,GSN,OGT4.55E-05 SYP,RAB3A,STXBP1,DLG44.55E-05 SF3A3,SRRM2,PRPF8,SNRNP200,SF3B3,RBM5,DDX5,SNW1,SF3B2,CRNKL1,EFTUD2,YBX1,DHX86.37E-05 SIRT1,CAV1,PTK2B,RASA1,PIK3R1,CTNNB1,AKT17.26E-05 GPI,ALDOA,SLC25A11,SLC25A12,GOT1,SLC25A13,GAPDH7.26E-05 SLC2A3,RANBP2,NUP98,TPR,NUP160,NUP62,NUP1537.40E-05 BCL2,PTK2B,THY1,SORBS1,ACTN17.98E-05 AP2A2,AP1B1,AP1G1,AP2B1,RAC1,AP2A18.02E-05 PPP1CA,MTOR,AKT1,PPP1R3D8.06E-05 FEZ1,CNR1,PTK2B,PTK6,CAMK2B,CAMK1D,CBFA2T28.08E-05 HDAC2,CTNNB1,HDAC18.08E-05 NAPA,NAPB,STXBP18.26E-05 CASP2,CASP6,PSMC2,CTSD,UQCRC2,SPG7,USP19,USP14,CAPN2,PSMD8,USP21,TMPRSS5,USP9X,DLD,USP1,USP7,CASP1,CASP7,USP8,UCHL3,BAP1,CASP3,CASP8,USP40

0.000114062 BCL11B,BCL2,TP53,CTNNB1,ZFP36L2,RPS60.000118052 PSMC2,DDB1,TP53,PSMD8,MAD1L1,ANAPC1,PSMA1,XPC,BUB3,ATM,PSMD30.000136495 RANBP2,NUP98,TPR,NUP160,NUP62,NUP1530.000168495 CTBP1,BCL2,CABLES1,TP53,HSPA8,TSC2,BAP1,ATM0.000210636 EIF2AK2,RPL7,RPL23,RPL15,RPL14,RPL13,RPL6,RPLP2,RPS60.000212116 FLNB,EZR,CTNNB1,TLN10.000212116 RASD2,DRD1,ADORA2A,SNCA0.000215957 PARK2,TRAF6,TGM2,ZDHHC17,VAPA,CTNNB1,PPM1A,GJA1,TRAF1,CASP1,NUP62

0.000227955 GRIN2A,BCL2,CNR1,PTK2B,PIK3R1,GRIN1,GSN,GSTP1,CASP80.000230883 G3BP2,RANBP2,NUP98,TPR,NUP62,NXT2,NUP1530.000243899 RPL7,RPL23,RPL15,RPL14,RPL13,EEF1A1,RPL6,RPLP2,RPS6

0.00025536 ILK,MAP3K10,MTOR,AKT1,CAMK2B,GSK3B,ATM0.000256677 SGK1,EIF2AK2,ILK,MAP3K10,MTOR,CTBP1,PACSIN1,CSK,PTK2B,PRKRA,APP,PTK6,CAMK2G,PRKAA2,TYK2,AKT1,CAMK2B,EGFR,GSK3B0.000284476 SLC41A1,SLC25A4,ATP2A2,CACNA1E,SLC2A3,RANBP2,NUP98,ITPR1,ATP6V0A1,SLC16A1,VDAC3,TPR,NUP160,SLC25A12,ABCC10,ATP1A1,NUP62,ATP6V0E1,VDAC2,ATP1B1,SLC15A4,KCNC1,VDAC1,NUP153,SLC25A130.000303244 TP53,APAF1,CASP7,CASP30.000316601 PAFAH1B1,GFAP,HDAC2,INPPL1,CBFA2T2

0.00033933 GRB2,MTOR,TNFSF13B,CSK,CAV1,PIK3R1,AKT1,RAC10.000341662 PAFAH1B1,FLNB,GRB2,HIP1,SIRT1,PAX6,DPYSL2,MLF1,CTBP1,NGFR,PTK2B,INA,TP53,DBN1,CAMK2G,AKT1,HUWE1,CAMK2B,BZW2,NDRG2,GSK3B,SQSTM10.000374048 PAFAH1B1,CASP2,NAPA,DPYSL2,MYH10,BCL2,ARF4,NR3C1,INPPL1,SPHK2,CTNS,ATM0.000441575 GRIN2A,CAV1,PTK2B,ENTPD6,SLC25A12,ACTB,SLC25A130.000527383 GRB2,ILK,PRKAA2,SEPT7,TSC2,CASP80.000575218 MTOR,AKT1,SORBS10.000575218 DPYSL2,DNM2,CTNNB10.000575218 HDAC2,CTNNB1,HDAC10.000587954 PSMC2,MTOR,SPG7,CUL2,AKT1,UCHL30.000588907 ATP5B,ATP5C1,ATP5F1,ATP5A10.000588907 ATP5B,ATP5C1,ATP5F1,ATP5A10.000588907 BCL2,CAMK2G,CAMK2B,GJA10.000591084 RPL7,RPL23,RPL15,RPL14,RPL13,RPL6,RPLP2,RPS60.000630816 PARK2,PSMC2,BCL2,TRAF6,PSMD8,HUWE1,PSMA1,PPIL2,PSMD30.000759375 VAMP2,SYT1,RAB3A,PCLO0.000759375 NSF,VAMP2,SYT1,RAB3A0.000781542 SIRT1,ILK,BCL2,TP53,NUP620.000814814 CAPZA1,PTK2B,SF3B3,TP53,TRAF1,MAX,CAPZA2,DLG4,CREBBP0.000829748 NCOR2,PAX6,PFKM,CACNA1E,PRKAA2,AKT1,RPS60.000852972 PARK2,PAX6,NCKAP1,MBP,NGFR,TP53,ADORA2A,SH3GL3,GSTP10.000855196 RPL7,RPL23,RPL15,RPL14,RPL13,RPL6,RPLP2,RPS60.000865421 MED15,PAX6,HMGB2,SMARCA4,SRCAP,TAF4,SUPT5H,MED23,SNW1,CHD3,NFYC,SMARCC2,HMGB10.000958163 ILK,PTK2B,CDH13,GSK3B0.000958163 BCL2,CACNA1E,DRD1,VDAC10.000965621 CASP2,PSMC2,TP53,PSMD8,PSMA1,ATM,PSMD30.000988676 SF3A3,SRRM2,PRPF8,SNRNP200,SF3B3,RBM5,DDX5,SNW1,SF3B2,CRNKL1,EFTUD2,YBX1,SUGP2,DHX8

0.0010052 ADD1,ADD2,GSN0.00101089 MTOR,PIK3R1,ASNS,GSTP1,GSS0.00101089 GRIN2A,DPYSL2,DRD1,ADORA2A,PDE1B

0.0010234 GRB2,ILK,PTK2B,MLLT4,CDH13,CLDN12,ARHGEF6,ACTN10.00117141 INPPL1,TSC2,HMGCR,NUP62,GSTP10.00117141 MAD1L1,TPR,ANAPC1,BUB3,ATM0.00117141 BCL2,AKT1,RAB14,SUMO1,MYCBP20.00131767 GRB2,MAPK1,G3BP2,TP53,GNB1,YWHAB,USP80.00133015 ILK,MYH10,TNFSF13B,SRRT,TP53,RAP1B,AKT1,GNB1,ZFP36L2,EGFR,EPS8,SPHK2,CUL1,USP8,CREBBP0.00133748 CASP6,DNAJA1,BCL2,DNAJA2,AKT1,HSPA40.00133968 USP19,USP9X,USP1,USP7,BAP10.00133968 PAFAH1B1,GPI,GRIN2A,EGR1,TMOD20.00135725 RPL7,RPL23,RPL15,RPL14,RPL13,AKT1,RPL6,RPLP2,RPS6

0.001481 FLII,DRD1,TPM2,ASPH,GJA1,SORBS1,MYL6,TLN1

0.001516 VDAC3,VDAC2,VDAC10.001516 CTBP1,TP53,NCOR10.001516 GFAP,DRD1,POU3F20.001516 HIP1,SNAP91,AP2B10.001516 MTOR,AKT1,TSC2

0.00152424 PAFAH1B1,PARK2,APP,SNCA,EPS80.00175205 GRIN2A,DPYSL2,CNR1,PTK2B0.00184143 PSMC2,PSMD8,ANAPC1,PSMA1,CUL1,BUB3,PSMD30.00184143 BCL11B,BAIAP2,APP,RAB3A,ACTB,SNAP91,SNAP25

0.0019076 BCL2,PTK2B,DBN1,ALDOA,INPPL10.0019076 CTH,PAH,CBS,ASNS,GOT10.0019076 PAFAH1B1,GRIN2A,YWHAE,GSK3B,BCAN

0.00201387 SGK1,XRCC6,SIRT1,MAPK1,BCL2,TP53,RAD23B,ATM,CASP30.00203527 SMARCA4,HDAC2,SUPT5H,HDAC1,KAT2B,SMARCC20.00208104 SIRT1,HDAC3,HDAC2,HDAC10.00214235 DRD1,RANBP2,MCM3AP,TPR,TSC2

0.0021839 GRB2,MTOR,PIK3R1,AKT1,RAB14,TSC2,GSK3B0.00219103 XRCC6,HMGB2,HMGB10.00219103 SIRT1,PRKAA2,GOT10.00219103 PRKAA2,CPT1B,CPT20.00219103 DPYSL2,NR3C1,ADORA2A0.00235817 DRD1,AKT1,KAT2B,SORBS1,GOT1,GSTP10.00235817 SLC25A3,ATP5B,SLC25A4,COX4I1,COX6C,ECH10.00236662 PPP2R2A,PPM1F,PPP1CA,BCL2,DUSP2,SBF1,PPM1A,DUSP80.00240196 BCL2,APP,MAX,GAPDH0.00240196 EZR,ADD1,ADD2,ACTN10.00244331 HMGB2,HMGB10.00244331 ENTPD2,ENTPD10.00244331 SIRT1,BECN10.00244331 SNCA,STX1A0.00244331 CTH,CBS0.00244331 XPC,RAD23B0.00244331 SIRT1,KAT2B0.00244331 CAMK2G,CAMK2B0.00244331 CNR1,AKT10.00244331 CEP250,CTNNB10.00244331 NAPA,NAPB0.00244331 SYP,AP3D10.00246793 PSMC2,PSMD8,ANAPC1,PSMA1,CUL1,BUB3,PSMD30.00252569 GRIN2A,CAV1,TP53,CEP250,TSC2,SQSTM10.00267681 GRIN2A,GRIN1,ADORA2A,SNCA0.00267681 GRIN2A,YWHAH,ADORA2A,YWHAG

0.0027254 PAFAH1B1,MYH10,APP,CAMK2B,DLG40.00281513 BTG1,ILK,PIK3R10.00281513 BCL2,CBS,GSN0.00314713 SIRT1,CAV1,FADS1,MAX0.00314713 BCL2,TP53,CASP7,CASP30.00367338 BCL2,CAV1,PTK2B,CAPN2,ITPR1,UBQLN1,TSC2,ATP1B1,CREBBP,ATM

0.00372488 TUBB,HDAC3,CEP63,NCOR10.00375268 PSMC2,BCL2,GSPT1,CUL2,PSMD8,CAMK2B,PSMA1,CUL1,PSMD30.00375549 BCL2,PRKAA2,ADORA2A0.00375549 GRIN2A,APP,GRIN10.00375549 BCL2,ADORA2A,NDUFS10.00375549 SIRT1,SMARCA4,HDAC10.00375549 PARK2,GRIN2A,DRD10.00375549 PAFAH1B1,CACNA1E,DRD1

0.0037772 HDAC3,NGFR,HDAC2,HDAC1,PPP1R13B0.00386687 PAFAH1B1,MAPK1,PPP1CA,MLF1,WDR6,TP53,CREBL2,RAB11A,SUPT5H,SEPT7,KAT2B,USP9X,BECN1,GNAI2,USP8,UPF1,ARL20.00428754 FMNL3,EZR,MYH10,PTK2B,DIAPH1,RASA1,ALDOA

0.0042945 EIF2AK2,MAP3K10,MTOR,PTK2B,PTK6,AKT1,CAMK2B,EGFR,ATM0.00432701 PSMC2,PSMD8,ANAPC1,PSMA1,BUB3,PSMD30.00432701 GRIN2A,GFAP,PAX6,NGFR,RAC1,CASP30.00466602 Ube3a,NEDD4L,UBA1,ADPRH,UBE2D2,USP21,AKT1,HUWE1,BAP10.00486032 TP53,PRKAA2,ASNS0.00486032 NFKB1,TRAF6,NGFR0.00486032 SIRT1,HDAC3,HDAC10.00528257 UBE2K,SIRT1,NEDD4L,PAX6,TRAF6,UBE2D2,AKT1,CUL1,UBE2H0.00533624 RASD2,CACNA1E,APP,DRD1,ADORA2A,PDE1B0.00535757 GPI,PFKM,LDHA,ALDOA,GAPDH

0.0056359 TUBB,CAPZA1,CAPZB,DNALI1,CAPZA2,RAC1,TLN10.00592355 SIRT1,NCOR2,CTBP10.00592355 PIK3R1,AKT1,SORBS10.00592355 SIRT1,PRKAA2,TSC20.00592355 ATP5B,NDUFS1,CTNS0.00594744 GRB2,DNM2,SNCA,CLTC0.00597571 SLC25A12,SLC25A130.00597571 SLC25A12,SLC25A130.00597571 KAT2B,CREBBP0.00597571 SIRT1,TP530.00597571 SLC25A4,GJA10.00597571 PIK3R1,SNCA0.00597571 GRIN2A,NR3C10.00597571 CDH13,RAC10.00597571 SIRT1,HDAC20.00624775 PSMC2,PSMD8,ANAPC1,PSMA1,CUL1,PSMD30.00732139 DRD1,THY1,SNCA0.00732139 NEDD4L,CAV1,SNCA0.00732139 PAFAH1B1,NUMA1,HTT0.00732139 PIK3R1,AKT1,TSC20.00732139 CAV1,AKT1,EGFR0.00732139 GFAP,DRD1,SNCA0.00732937 CTH,ASNS,GOT1,CTNS,GSS0.00749399 PARK2,GRIN2A,DLG4,VDAC10.00749399 ECH1,HADHA,CPT1B,CPT20.00751476 BCL2,CTNNB1,THY1,EGFR,CYFIP2,RAPGEF1

0.0077056 SGK1,TP53,BMP2K,RAPGEF1,NCOR1

0.00780061 ELK1,NFKB1,MAPK1,BCL2,TRAF6,CAPZA1,APP,POLR3E,TRAF3,CAPZA2,CASP1,CREBBP,HMGB10.00836772 DNM2,ATP6V0A1,CLTC,ATP6V0E10.00836772 CASP6,BCL2,CAV1,TP530.00836779 DNAJA1,DNAJB1,HSPA8,HSPA4,HSPA20.00879319 MAPK1,ILK,PTK2B,DRD1,PIK3R1,CDH13,EGFR0.00879319 GTF3C5,MLF1,NACA,CREBL2,NR3C1,MYEF2,NUP620.00880919 ECH1,HADHA,SNCA,CPT1B,FABP3,CPT20.00883609 NEDD4L,ARNTL,PSMD30.00883609 CAV1,GRIN1,SNCA0.00926371 PARK2,UBE2K,UBE2D2,UBE2H

0.0093475 GPI,ILK,BCL2,RASA1,ADORA2A,SNCA0.00986693 GRIN2A,BECN10.00986693 TSC2,OGT0.00986693 SLC25A4,VDAC30.00986693 TOMM22,HSPA40.00986693 SLC25A4,GSTP10.00986693 SPHK2,SGPP20.00986693 ATP5B,ATP5A10.00986693 MTOR,GSK3B0.00986693 ADORA2A,CAMK2B0.00986693 CTH,CBS0.00986693 AKT1,EGFR0.00986693 SIRT1,HDAC10.00994337 BCL2,TNFSF13B,CASP30.00994337 MBP,NGFR,THY10.00994337 FMNL3,DIAPH1,FHOD30.00994856 APP,ALDOA,STXBP1,CALU,ACTN1,TLN1

0.0102955 ATP5B,ATP6V0A1,ATP6V0E1,ATP5A10.0102955 BCL11B,BCL2,LMO4,CTNNB10.0102975 BCL2,PRKRA,YWHAB,OGT,HMGB10.0106513 XRCC6,SIRT1,SSRP1,DDB1,SUMO1,RAD51C,XPC,RAD23B,USP1,RECQL5,UPF1,ATM0.0118361 AKT1,PGM1,UGP20.0118361 PARK2,NAPA,NAPB0.0118361 DIAPH1,RAC1,GSN0.0118361 BCL11B,CNR1,PRKAA20.0118361 DPYSL2,YWHAH,YWHAG0.0118374 CBS,ASNS,GSTP1,GSS0.0118374 MTOR,GDF11,GDF10,VPS540.0119536 SIRT1,BTG1,BCL2,SMARCA4,TP53,CTH,NDUFS30.0129238 SREBF2,PTK2B,CTNNB1,AKT1,MAT2A0.0130013 PAFAH1B1,RANBP2,NUP98,MAD1L1,NUP160,BUB30.0130179 ATP2A2,GRIN1,ITPR1,REST0.0138085 CAPZA1,CAPZB,CAPZA20.0138085 MYO9B,MYH10,MYO6

0.014218 CASP6,SIN3A,PTK2B,MAX0.014218 BCL2,CAV1,AKT1,SNCA0.014218 CCT4,CCT2,TBCD,TCP10.014279 NFKB1,MAPK1,TRAF6,CSK,PIK3R1,THY1

0.0145749 SNCA,INPPL10.0145749 TP53,RPS60.0145749 EIF2AK2,BCL20.0145749 TCP1,ARL20.0145749 EZH1,WHSC10.0145749 PPP1CA,PPP1R3D0.0145749 BCL2,ITPR10.0145749 AKT1,EGFR0.0145749 YWHAE,YWHAB0.0145749 BAG1,DNAJB10.0150152 TFEB,GPI,BCL2,POU2AF10.0150355 SYMPK,FEZ1,ATP2A2,BTBD9,PTK2B,APP,NEGR1,MLLT4,CTNNB1,CDH13,CNTN1,INPPL1,RAC1,CD22,CASK,BCAN,TLN1,ENTPD1

0.015054 PAFAH1B1,TUBB,CEP63,SEPT7,DCTN1,CLTC,ANAPC1,USP9X,RPS60.0152494 CDH13,TSC2,SNAP910.0152494 GRIN2A,ASNS,MAT2A0.0152494 TP53,DLD,RPS60.0152494 PRKAA2,CPT1B,CPT20.0175557 SIRT1,TP53,NR3C1,PPM1A0.0175557 HDAC2,CTNNB1,HDAC1,CREBBP0.0175588 GCNT1,POMT2,OGT0.0175588 GRB2,SIRT1,TP530.0175588 CTNNB1,CAMK2B,GSS0.0175588 CAPZB,CDH13,RAC10.0175588 HDAC3,AKT1,NCOR10.0178093 ADAR,RNGTT,RBM5,CRNKL1,SUGP2,DHX80.0190102 HMGB2,HMGB10.0190102 STX1A,SNAP250.0190102 AKT1,RPS60.0190102 TMOD2,VDAC10.0190102 MTOR,RAC10.0190102 BCL2,TP530.0190102 BCL2,TP530.0190102 PAFAH1B1,HTT0.0190102 PFKM,ALDOA0.0190102 MAPK1,GSTP10.0190102 GRIN2A,PDE1B0.0190102 HDAC2,HDAC10.0190102 TSC2,NCOR10.0190102 CASP2,SMARCA40.0190102 NFKB1,NDRG20.0190102 HDAC1,REST0.0190102 PAFAH1B1,MYH100.0190102 PARK2,GRIN2A0.0190102 TBCD,CTNNB10.0190431 SSRP1,TAF4,SUPT5H,TAF4B,TBP0.0192592 SEC24C,PSMC2,PSMD8,PSMA1,SEC23A,PSMD30.0194216 SRGAP1,MYO9B,CDH13,ARHGAP10.0199115 ADD1,BCL2,VPS54

0.0199115 BCL2,USP19,USP70.0199115 TRRAP,SRCAP,CREBBP0.0199115 TP53,AKT1,ARNTL

0.019981 PAFAH1B1,RANBP2,NUP98,MAD1L1,NUP160,BUB30.0210458 HMGB2,TSC2,HMGB10.0210458 GRB2,PTK2B,TP530.0210458 PPP1CA,PPP1R3D,GSK3B0.0210458 LDHA,SLC16A1,DLD0.0210458 BCL2,NDUFS3,NDUFS10.0210458 DDB1,XPC,RAD23B

0.021088 SGK1,PAX6,AKT1,RAC10.021088 MAPK1,YWHAB,RAPGEF1,GNAI2

0.0224485 RASD2,ILK,MTOR,EGFR0.0224485 BCL11B,NGFR,CTNNB1,WNT10A0.0238902 MAP3K10,TRAF6,PTK2B0.0245963 TBCD,SNCA0.0245963 HDAC2,HDAC10.0245963 SYP,PPFIA30.0245963 DRD1,PDE1B0.0245963 EGR1,ATM0.0245963 PTK2B,RAP1B0.0245963 PAX6,EGFR0.0245963 PARK2,AKT10.0245963 ATP2A2,ATP1A10.0245963 HDAC3,HDAC10.0245963 MTOR,CHD80.0248565 MAPK1,MBP,BCL2,ASNS,GSTP10.0254441 BCL2,TRAF6,APP,CASP10.0258355 ILK,PIK3R1,NDRG20.0258355 NAPA,VAMP2,VAPA0.0258355 TFEB,SP1,EGFR0.0258355 DUSP2,CAV1,DUSP80.0258355 NGFR,CTNNB1,WNT10A0.0270169 PARK2,NEDD4L,DDB1,HUWE10.0270169 FEZ1,GRIN2A,CTNNB1,AKT10.0280403 ELK1,NFKB1,MAPK1,TRAF6,TRAF30.0284234 MTOR,PTK2B,PFN20.0284234 HMGB2,CASP3,HMGB10.0284234 MAP3K10,MTOR,BCL20.0284234 ADD1,HSPA4,ADD20.0284234 ARFGAP1,HTT,GBF10.0284234 ILK,NUP62,YWHAG0.0284234 PAFAH1B1,APP,ASNS0.0286565 FMNL3,PACSIN1,DIAPH1,THY1,CAPZB,PCLO0.0286565 GRB2,CAV1,PIK3R1,SLC16A1,PPIL2,ATP1B10.0288963 SP1,PPP1CA,RAB3A,NR3C1,HMGB10.0296726 MTOR,RPS60.0296726 PGM1,UGP2

0.0296726 BCL2,XPC0.0296726 MTOR,PRKAA20.0296726 BCL2,GSTP10.0296726 BTG1,CTNNB10.0296726 YWHAH,NR3C10.0296726 PTK2B,SORBS10.0296726 CNR1,NISCH0.0296726 NUMA1,MAD1L10.0296726 CTBP1,SNCA0.0296726 DBN1,CAMK1D0.0299541 CACNA1E,ADORA2A,CACNA2D10.0299541 SF3A3,PRPF8,SF3B30.0299541 PIK3R1,AKT1,SORBS10.0299541 HDAC3,APP,NCOR10.0299541 SIRT1,KAT2B,CASP30.0299541 BCL2,CNR1,BAG1

0.030242 NCOR2,SIN3A,MYH10,ADD1,CHD8,TP53,CTNNB1,YBX10.0303114 FLNB,CAV1,SIN3B,MYL60.0303114 PAX6,GDF11,APP,REST0.0303114 BCL11B,HDAC2,CTNNB1,HDAC1

0.033299 ATP5B,ATP5C1,ATP6V0E1,ATP5A10.0354873 SIRT1,REST,HMGB10.0354873 TNFRSF8,PTK2B,TRAF30.0355215 HMGB2,HMGB10.0355215 NR3C1,ADORA2A0.0355215 CDH13,NISCH0.0355215 APP,DRD10.0355215 HDAC2,HDAC10.0355215 SNCA,AP2B10.0355215 TP53,ATM0.0355215 RASA1,PIK3R10.0355215 GRB2,CEP630.0355215 MYO6,TP530.0355215 LMO4,GSK3B0.0355215 TP53,GSK3B0.0355215 ENTPD6,SNCA0.0355215 UQCRC2,ATP5C10.0355215 NSF,SNCA0.0355326 CASP2,NFKB1,TNFRSF8,CASP10.0355326 PSMC2,PSMD8,PSMA1,PSMD30.0364232 SIRT1,DDB1,UBE2D2,RAD23B0.0388428 GPI,ADORA2A,AKT1,SNCA0.0389361 ILK,MTOR,BAIAP20.0389361 ILK,ADORA2A,GJA10.0410122 NAPA,TUBB,BAG1,POU3F2,MYEF20.0410122 SIRT1,MTOR,PIK3R1,AKT1,HSPA20.0411674 SIRT1,MAP3K10,HDAC2,SUMO10.0417713 GNB1,GNAI2

0.0417713 RAB14,AP2A10.0417713 BCL2,CTNNB10.0417713 BCL2,TP530.0417713 SP1,SMARCA40.0417713 PAX6,AP3D10.0417713 ZFYVE27,RAB11A0.0417713 PARK2,HUWE10.0417713 SRRT,NR3C10.0417713 RPL7,RPL140.0417713 NAPA,RAB140.0419332 SIRT1,MAPK1,ILK,TNFSF13B,PTK2B,DNAJA2,HDAC2,HDAC1,POU3F2,EGFR,SPHK2,GNAI20.0421964 AKT1,CAPZB,TSC2,GSN0.0424494 SIN3A,TP53,CTNNB10.0424494 MYO9B,THY1,ARHGAP10.0448094 RASA1,RAB11A,SEPT7,BECN10.0449744 RNGTT,SUPT5H,RNMT0.0449744 YWHAE,YWHAB,YWHAG0.0478409 HMGB10.0478409 HMGB10.0478409 HSPA20.0478409 HSPA20.0478409 GAPDH0.0478409 RPS60.0478409 BAP10.0478409 GSTP10.0478409 GSTP10.0478409 GSTP10.0478409 GSTP10.0478409 NCOR10.0478409 NCOR10.0478409 NCOR10.0478409 GNAI20.0478409 PFN20.0478409 MYCBP20.0478409 NDRG20.0478409 ATP1A10.0478409 ATP1A10.0478409 NISCH0.0478409 SPHK20.0478409 CBS0.0478409 CBS0.0478409 CBS0.0478409 CBS0.0478409 DLD0.0478409 DLD0.0478409 DLD0.0478409 MAD1L10.0478409 PAH

0.0478409 PAH0.0478409 PAH0.0478409 SNCA0.0478409 SNCA0.0478409 SNCA0.0478409 SNCA0.0478409 SNCA0.0478409 SNCA0.0478409 SNCA0.0478409 REST0.0478409 REST0.0478409 REST0.0478409 GJA10.0478409 CAMK1D0.0478409 HTT0.0478409 CAMK2B0.0478409 CAMK2B0.0478409 SLC16A10.0478409 SUCLA20.0478409 ENTPD30.0478409 AKT10.0478409 AKT10.0478409 ASPH0.0478409 CTNNB10.0478409 CTNNB10.0478409 CTNNB10.0478409 CTNNB10.0478409 CTNNB10.0478409 ADORA2A0.0478409 NR3C10.0478409 NR3C10.0478409 FNTA0.0478409 CTH0.0478409 DNM1L0.0478409 DNM1L0.0478409 RAB3A0.0478409 RAB3A0.0478409 RAB3A0.0478409 VAPA0.0478409 RASA10.0478409 MYO60.0478409 DRD10.0478409 APP0.0478409 DOT1L0.0478409 HMGB20.0478409 PTK2B0.0478409 PTK2B0.0478409 PTK2B

0.0478409 PTK2B0.0478409 CACNA1E0.0478409 CAV10.0478409 CNR10.0478409 CNR10.0478409 LMO40.0478409 LMO40.0478409 TNFSF13B0.0478409 YWHAH0.0478409 EGR10.0478409 EGR10.0478409 EGR10.0478409 BCL20.0478409 BCL20.0478409 BCL20.0478409 BCL20.0478409 BCL20.0478409 BCL20.0478409 BCL20.0478409 BCL20.0478409 BCL20.0478409 CTBP10.0478409 MTOR0.0478409 MTOR0.0478409 MTOR0.0478409 PAX60.0478409 PAX60.0478409 PAX60.0478409 PAX60.0478409 GFAP0.0478409 GFAP0.0478409 SLC25A40.0478409 GRIN2A0.0478409 NCOR20.0478409 EIF2AK20.0478409 CASP60.0478409 CASP60.0478409 TNFRSF80.0478409 MYO9B0.0478409 SIRT10.0478409 SIRT10.0478409 SIRT10.0478409 SIRT10.0478409 SIRT10.0478409 SIRT10.0478409 SIRT10.0478409 NFKB10.0478409 GPI

0.0478409 SGK10.0478409 SGK10.0478409 PAFAH1B10.0478409 PAFAH1B10.0478409 PAFAH1B1

0.048149 BAG1,PTK2B0.048149 SEC24C,SEC23A0.048149 DRD1,ADORA2A0.048149 RPS6,NOP140.048149 DIAPH1,GSK3B0.048149 USP8,BAP10.048149 DNAJB1,HSPA80.048149 HDAC3,NCOR10.048149 DRD1,ADORA2A0.048149 GRIN2A,SNAP250.048149 NDUFV2,SIN3B0.048149 CAV1,AKT10.048149 SUMO1,GSK3B

0.0482757 MAPK1,BCL2,CAV1,CTNNB10.0482757 ELK1,NFKB1,MAPK1,TRAF60.0485201 PSMC2,PSMD8,PAH,DLD,PSMA1,ASNS,GOT1,PSMD30.0489141 TBCD,CLDN12,ARL20.0489141 CTH,CTNS,GSTP10.0489141 CASP2,CASP7,CASP30.0493497 CASP6,PIK3R1,CTNNB1,GSTP1,CASP80.0494488 GTF3C5,POLR3E,TBP0.0494488 GRIN2A,CNR1,DRD10.0494488 MAPK1,MTOR,PTK2B0.0495331 TNFSF13B,CDH130.0495331 AKT1,SORBS10.0495331 MAPK1,MYCBP20.0495331 MTOR,RAC10.0495331 ARFGAP1,GBF10.0495331 SLC25A4,AKT10.0495331 RASA1,ARPC1A

0.049927 ATP2A2,GJA1,ATP1A1,ATP5A1,ATP1B10.0499587 SIRT1,RPL7,RPL14,RPS6,NOP14

ELK1,GRB2,CASP2,NFKB1,AP2A2,MAPK1,YWHAE,ZFYVE27,HDAC3,MTOR,TRIO,TRAF6,NGFR,MAGED1,PIK3R1,HDAC2,ITPR1,ADORA2A,AKT1,HDAC1,PDE1B,CLTC,TSC2,YWHAB,GSK3B,AP2B1,RAC1,ARHGEF6,RAPGEF1,ARHGEF7,SQSTM1,AP2A1,CASP3HIP1,CASP2,NFKB1,CASP6,PPM1F,PSMC2,TJP2,API5,YWHAE,NCKAP1,ADD1,TRIO,BCL2,TRAF6,NGFR,PTK2B,HMGB2,MAGED1,TP53,MEF2D,PSMD8,DNM1L,FNTA,ADORA2A,CTNNB1,AKT1,PDE1B,PPP1R13B,HTT,GJA1,APAF1,UBQLN1,PSMA1,NISCH,CUL1,CYFIP2,YWHAB,CASP1,TP53INP1,RAC1,ARHGEF6,CASP7,NDUFS1,GSN,ARHGEF7,SQSTM1,VDAC1,CASP3,PSMD3,HMGB1XRCC6,AP2A2,PSMC2,SLC25A4,SSRP1,RPL7,RPL23,RPL15,RPL14,RPL13,RNGTT,RANBP2,TAF4,PSMD8,NUP98,AP1B1,AP1G1,SUPT5H,TAF4B,TPR,NUP160,PSMA1,TBP,AP2B1,RAC1,NUP62,RPL6,ZNF24,RPLP2,NUP153,AP2A1,RPS6,RNMT,PSMD3GRB2,SP1,UBR4,VPRBP,SIRT1,PSMC2,MAPK1,EIF2AK2,SLC25A4,NEDD4L,YWHAE,CTBP1,DDB1,CAV1,RNGTT,NACA,SRCAP,TP53,CUL2,TAF4,PIK3R1,DYNC1I2,HSPA8,NUP98,HDAC1,KAT2B,SF3B2,CUL1,USP7,TBP,FBLN1,VDAC1,NUP153,CREBBPFLNB,PPP2R2A,NFKB1,SRGAP1,TNFRSF8,MAPK1,GRIN2A,RASD2,SRGAP2,DPYSL2,MAP3K10,DNM2,MTOR,TRAF6,BAIAP2,ARHGAP18,TNFSF13B,NGFR,PTK2B,SNX27,ZDHHC17,YWHAZ,MLLT4,CREBL2,RASA1,VAPA,PRKAA2,PIK3R1,RAP1B,CORO1C,ITPR1,NR3C1,AKT1,TRIP10,PDE1B,GNB1,CAMK2B,PI4KA,PPM1A,GJA1,TRAF1,TSC2,EGFR,EPS8,TRAF3,ARHGAP1,NDRG2,DLG4,CASP1,RAPGEF1,INPP5B,GNAI2,SH3GL3,ARHGEF7,CREBBP,ATM,OGT,PPP1R16BSGK1,HIP1,CASP2,SIRT1,PSMC2,BTG1,BCL2,TRAF6,DUSP2,MAGED1,TP53,PSMD8,CAMK1D,APAF1,TRAF1,PSMA1,TRAF3,CASP1,ACTN1,CASP3,CASP8,Casp10,PSMD3TNFRSF8,EIF2AK2,BTG1,BCL11B,CTBP1,CSK,CAV1,GDF11,PTK2B,PRKRA,WDR6,TP53,CUL2,RBM5,CTH,ADORA2A,CTNNB1,ASPH,KAT2B,GJA1,REST,CDH13,FABP3,INPPL1,TSC2,CUL1,NUP62,BECN1,BAP1GRB2,MAPK1,SIN3A,ATP2A2,CSK,CAPZA1,CAV1,CABLES1,APP,YWHAZ,TP53,PIK3R1,RAP1B,ALDOA,HDAC2,ITPR1,ADORA2A,AKT1,CAPZB,HDAC1,PDE1B,SLC16A1,GNB1,CALU,RAD51C,PPIL2,CAPZA2,RAC1,ACTN1,ATP1B1,GNAI2,TLN1,ENTPD1PARK2,UBE2K,PSMC2,Ube3a,USP19,UBE2D2,CUL2,USP14,USP21,USP9X,PSMA1,USP1,CUL1,USP7,USP8,UCHL3,UBE2H,BAP1,SQSTM1,USP40PAFAH1B1,SYN1,AP2A2,NSF,MAPK1,GRIN2A,EPB41L1,VAMP2,MBP,SYT1,CACNA1E,MYO6,CAMK2G,USP14,RAB3A,GRIN1,HSPA8,STXBP1,GNB1,CAMK2B,PI4KA,KCNN3,DLG4,SNAP91,AP2B1,STX1A,GNAI2,KCNC1,SNAP25,AP2A1ELK1,TFEB,SP1,XRCC6,ZNF292,SREBF2,NFKB1,SIRT1,Ube3a,PAX6,BCL11B,NFYA,EGR1,TRAF6,LMO4,BAG1,HMGB2,CHD8,APP,MYO6,SMARCA4,TP53,MEF2D,PIK3R1,GRIN1,HDAC2,SUPT5H,CTNNB1,AKT1,HDAC1,KAT2B,CBFA2T2,ARNTL,SQSTM1,CREBBP,HMGB1SF3A3,MED15,SSRP1,RPL7,RPL23,RPL15,RPL14,RPL13,PRPF8,SNRNP200,RNGTT,SF3B3,EEF1A1,TAF4,RBM5,NR3C1,SUPT5H,TAF4B,MED23,SNW1,KAT2B,SF3B2,TBP,EFTUD2,RPL6,YBX1,RPLP2,CREBBP,RPS6,RNMTGRB2,AP2A2,MAPK1,ARF4,CSK,PTK2B,PIK3R1,CLTC,EGFR,EPS8,YWHAB,AP2B1,ARHGEF7,AP2A1GRB2,COL4A5,AP2A2,SRGAP1,FEZ1,MAPK1,SRGAP2,PAX6,EZR,DPYSL2,MYH10,TRIO,NGFR,STIP1,CNTN1,CLTC,EGFR,YWHAB,DLG4,MYL6,GSK3B,AP2B1,RAC1,TLN1,AP2A1PAFAH1B1,FLNB,FMNL3,MYH10,ADD1,CAPZA1,DIAPH1,ARPC1A,CORO1C,TRIP10,CAPZB,ADD2,FHOD3,NISCH,CAPZA2,PFN2,CORO1BSEC16A,SEC24C,AP2A2,NSF,VAMP2,ARF4,AP3D1,ARFGAP1,RAB11A,AP1B1,AP1G1,STXBP1,RAB14,CLTC,GGA3,TSC2,AP2B1,SEC23A,STX1A,GSNSYN1,VAMP2,SYT1,RAB3A,HSPA8,PPFIA3,STXBP1,RAB14,SNAP91,AP2B1,STX1A,SNAP25GPI,PFKM,FABP5,PIK3R1,ALDOA,AKT1,SLC25A11,INPPL1,SLC25A12,PGM1,NISCH,GOT1,SLC25A13,UGP2,GAPDHPARK2,HIP1,CTSD,ZFYVE27,BCL2,SPG7,SPG20,UBA1,APP,VAPA,ITPR1,HTT,DCTN1,SNCA,UBQLN2,TBP,NUP62,ATMNDUFV1,ATP5B,COX4I1,UQCRC2,NDUFV2,COX6C,ATP5C1,ATP5F1,NDUFS3,ATP5A1,NDUFS1,NDUFB10,NDUFA8,NDUFB8PPP2R2A,EDC4,PSMC2,DDX24,RPL7,RPL23,RPL15,RPL14,RPL13,YWHAZ,HSPA8,PSMD8,SMG5,AKT1,BZW2,PSMA1,YWHAB,RPL6,RPLP2,UPF1,RPS6,PSMD3HIP1,AP2A2,DNM2,PACSIN1,APP,MYO6,AP1B1,AP1G1,FNBP1,TRIP10,DNM1,INPPL1,TSC2,SH3GL3,AP2A1GPI,PPP1CA,PFKM,SLC2A3,B4GALT6,RANBP2,NUP98,ALDOA,AKT1,SLC25A11,TPR,NUP160,SLC25A12,PGM1,GOT1,PPP1R3D,GSK3B,NUP62,MGAT1,NUP153,SLC25A13,UGP2,GAPDHCASP6,TJP2,ADD1,HMGB2,DNM1L,FNTA,CTNNB1,CASP7,GSN,CASP3,HMGB1PPP2R2A,EDC4,PSMC2,RPL7,RPL23,RPL15,RPL14,RPL13,YWHAZ,HSPA8,PSMD8,SMG5,AKT1,PSMA1,YWHAB,RPL6,RPLP2,UPF1,RPS6,PSMD3SIRT1,BCL11B,SIN3A,BCL2,ADAR,PTK2B,CHD8,TP53,PRKAA2,PIK3R1,HDAC2,CTNNB1,AKT1,HDAC1,EGFR,ASNS,GSK3B,NUP62,GSTP1,ATM,CASP3,RPS6SGK1,MAPK1,CNR1,BAG1,PTK2B,DNAJB1,PRKRA,STIP1,TRAP1,PRKAA2,HSPA8,FADS1,HSPA4,EGFR,TP53INP1,SQSTM1,HSPA2PAFAH1B1,NDUFV1,SYN1,DYNC1H1,SLC25A3,ATP5B,FEZ1,GRIN2A,SLC25A4,SLC35F5,ATP2A2,UQCRC2,G3BP2,HDLBP,NDUFV2,CACNA1E,DYNC1I2,FADS1,AKT1,NDUFS3,SLC25A11,GJA1,CPT1B,CPT2,SORBS1,ATP6V0E1,ATP1B1,NDUFS1,NDUFB10,CTNS,NDUFA8,NDUFB8,SLC25A13SRGAP1,MYO9B,MAPK1,RASD2,SRGAP2,TRIO,ARHGAP18,ARF4,G3BP2,RAB10,RAB28,RAB3A,RAP1B,RAB11A,TRIP10,RAB14,ARHGAP1,YWHAB,RAC1,ARHGEF6,INPP5B,ARHGEF7,ARL2MECP2,XRCC6,NFKB1,SIRT1,SIN3A,MAP3K10,HDAC3,CTBP1,TRAF6,HMGB2,CHD8,SMARCA4,TP53,HSPA8,HDAC2,CTNNB1,HDAC1,SNW1,REST,SUMO1,SIN3B,YWHAB,CBFA2T2,YBX1,ZNF24,SMARCC2PAFAH1B1,FEZ1,DPYSL2,SPG7,NDUFV2,CABLES1,GDF11,INA,SMARCA4,DBN1,MEF2D,CAMK2G,FNBP1,AKT1,CAMK2B,BZW2,CAMK1D,DCTN1,APAF1,NDRG2,DLG4,GSK3B,TMOD2,ARHGEF7,SMARCC2,GSSSEC16A,NSF,COG1,ARF4,RAB10,SNX25,SNX27,ARFGAP1,NACA,VPS39,RANBP2,RAB3A,RAB11A,NUP98,STXBP1,RAB14,VPS54,TPR,CHCHD4,NUP160,SEC61A2,NUP62,SLC15A4,NXT2,VPS35,NUP153RASD2,GNAZ,DNM2,ARF4,GSPT1,RAB28,RAB3A,RAP1B,RAB11A,GNB1,DNM1,RAB14,RAC1,EFTUD2,GNAI2,ARL2SREBF2,GRIN2A,DPYSL2,HDAC3,BCL2,BAG1,CAV1,PTK2B,DRD1,YWHAZ,TP53,PIK3R1,ADD3,ADORA2A,CTNNB1,HADHA,SNCA,FABP3,INPPL1,XPC,ATP1A1,MAT2APAFAH1B1,DYNC1H1,PSMC2,TUBB,YWHAE,RANBP2,CEP63,DYNC1I2,PSMD8,CEP250,NUP98,NUMA1,DCTN1,TUBG1,MAD1L1,ANAPC1,NUP160,PSMA1,CUL1,BUB3,YWHAG,PSMD3SIRT1,MTOR,BCL2,EGR1,FADS1,NR3C1,HADHA,FABP3,INPPL1,MAX,OGTSEC24C,AP2A2,NAPA,YWHAH,AP3D1,DRD1,MYO6,NAPB,TOMM22,AP1B1,AP1G1,CLTC,GGA3,AP2B1,SEC23A,STX1A,AP2A1HDAC3,ASXL1,TRRAP,CABIN1,DOT1L,CHD8,SRCAP,PRKAA2,EP400,USP21,HDAC2,EZH1,NR3C1,HDAC1,CHD3,NCOR1,BAP1,WHSC1NFKB1,API5,HDAC3,BCL2,TRAF6,NGFR,BAG1,YWHAZ,NR3C1,AKT1,HDAC1,HSPA9,SNCA,SPHK2,BECN1,GSTP1,SQSTM1

ELK1,SP1,XRCC6,NFKB1,MAPK1,PAX6,ILK,DNM2,EGR1,YWHAH,HMGB2,CHD8,SMARCA4,TP53,TAF4,USP21,HDAC2,CTNNB1,HDAC1,PPM1A,REST,TBP,NUP62,NFYC,CREBBP,SMARCC2DNAJA1,CCT4,CCT2,DNAJC21,DNAJB1,TRAP1,RANBP2,DNAJC1,HSPA8,TBCD,TCP1,PPIB,DNAJA2,HSPA9,PPIL2,NFYCSEC24C,NAPA,VAMP2,DNM2,ARFGAP1,HSPA8,AP1B1,AP1G1,GJA1,CLTC,GBF1,SEC23AHIP1,CASP6,MAPK1,MAP3K10,NGFR,PRKRA,APP,TGM2,TP53,NDUFS3,PPP1R13B,TRAF3,USP7,TP53INP1,CASP7,CASP3FABP5,SLC2A3,RANBP2,NUP98,AKT1,TPR,SORBS1,NUP160,NUP62,NUP153

GRB2,MAPK1,MTOR,BAIAP2,PRKAA2,PIK3R1,AKT1,ATP6V0A1,PPM1A,SORBS1,TSC2,YWHAB,ATP6V0E1,RPS6NDUFV1,NDUFV2,NDUFS3,DLD,NDUFS1,NDUFB10,NDUFA8,NDUFB8SRGAP1,MYO9B,SRGAP2,TRIO,ARHGAP18,G3BP2,RASA1,TRIP10,TSC2,ARHGAP1,RAC1,ARHGEF6,RAPGEF1,INPP5B,ARHGEF7

CASP2,YWHAE,TRIO,TRAF6,NGFR,CAV1,MAGED1,RAC1,ARHGEF6,ARHGEF7,SQSTM1,CASP3CASP2,SIRT1,TNFRSF8,GRIN2A,DNM2,CNR1,TP53,PIK3R1,RBM5,CTNNB1,REST,ARHGEF7,ATM,RPS6,HMGB1

TFEB,SP1,HIP1,ZNF292,SFMBT2,NCOR2,BTG1,SSRP1,PAX6,BCL11B,NFYA,DNM2,ZNF207,ASXL1,LMO4,TRRAP,BATF,FLII,POU2AF1,MAGED1,SMARCA4,TP53,CREBL2,EEF1A1,MEF2D,PRKAA2,EP400,DNAJC1,HDAC2,EZH1,FADS1,NR3C1,ADORA2A,TAF4B,MED23,HDAC1,POU3F2,REST,ZFP36L2,CHD3,MAX,MYCBP2,TBP,ZNF91,RPL6,EWSR1,YBX1,PSPC1,NCOR1,NFYC,CREBBP,WHSC1,SMARCC2MAPK1,ATP2A2,APP,YWHAZ,PIK3R1,ENTPD2,ALDOA,ITPR1,AKT1,PDE1B,GNB1,CALU,RAC1,ACTN1,GNAI2,TLN1,ENTPD1

MECP2,NFKB1,SIRT1,NCOR2,HDAC3,CTBP1,EGR1,TRAF6,CAV1,SMARCA4,TP53,HDAC2,EZH1,SUPT5H,CTNNB1,HDAC1,REST,YBX1,NCOR1,ZMYND8,CREBBP,WHSC1,HMGB1

NFKB1,SSRP1,PAX6,NFYA,EGR1,LMO4,RNGTT,POU2AF1,MAF,MEF2D,TAF4,NR3C1,SUPT5H,TAF4B,MAX,TBP,YBX1,NCOR1,RNMTSLC25A4,MARCKS,VAMP2,CNR1,CACNA1E,RAP1B,ITPR1,STXBP1,STX1A,SNAP25GRB2,CASP2,SREBF2,SIN3A,CNR1,FADS1,NR3C1,DLD,HMGCR,CASP7,GSN,GSSPAFAH1B1,DYNC1H1,TUBB,DNM2,YWHAE,CEP63,DYNC1I2,CEP250,NUMA1,DCTN1,TUBG1,YWHAG

SEC24C,CCT4,CCT2,RPL7,RPL23,RPL15,RPL14,RPL13,B4GALT6,EEF1A1,TBCD,TCP1,PIGM,SEC23A,RPL6,MGAT1,RPLP2,RPS6SLC25A4,MARCKS,VAMP2,CACNA1E,PRKAA2,RAP1B,ITPR1,STXBP1,GNB1,STX1A,SNAP25MYO9B,PSMC2,ATP5B,ATP2A2,HSPA8,ATP5C1,ATP5F1,ATP1A1,ATP5A1,ENTPD1NCOR2,SIN3A,HDAC3,PRKAA2,FADS1,HADHA,CPT1B,INPPL1,CPT2,SIN3B,NCOR1,CREBBPILK,MLF1,WDR6,TP53,CUL2,PRKAA2,KAT2B,PPM1A,TSC2,CUL1,TP53INP1,ATM

EIF2AK2,RPL7,RPL23,RPL15,TNIP1,RPL14,RPL13,MRPS5,NACA,GSPT1,EEF1A1,AKT1,GCN1L1,RPL6,RPLP2,RPS6

SF3A3,SRRM2,PRPF8,SNRNP200,SF3B3,RBM5,DDX5,SNW1,SF3B2,CRNKL1,EFTUD2,YBX1,DHX8

CASP2,CASP6,PSMC2,CTSD,UQCRC2,SPG7,USP19,USP14,CAPN2,PSMD8,USP21,TMPRSS5,USP9X,DLD,USP1,USP7,CASP1,CASP7,USP8,UCHL3,BAP1,CASP3,CASP8,USP40

PSMC2,DDB1,TP53,PSMD8,MAD1L1,ANAPC1,PSMA1,XPC,BUB3,ATM,PSMD3

PARK2,TRAF6,TGM2,ZDHHC17,VAPA,CTNNB1,PPM1A,GJA1,TRAF1,CASP1,NUP62

SGK1,EIF2AK2,ILK,MAP3K10,MTOR,CTBP1,PACSIN1,CSK,PTK2B,PRKRA,APP,PTK6,CAMK2G,PRKAA2,TYK2,AKT1,CAMK2B,EGFR,GSK3BSLC41A1,SLC25A4,ATP2A2,CACNA1E,SLC2A3,RANBP2,NUP98,ITPR1,ATP6V0A1,SLC16A1,VDAC3,TPR,NUP160,SLC25A12,ABCC10,ATP1A1,NUP62,ATP6V0E1,VDAC2,ATP1B1,SLC15A4,KCNC1,VDAC1,NUP153,SLC25A13

PAFAH1B1,FLNB,GRB2,HIP1,SIRT1,PAX6,DPYSL2,MLF1,CTBP1,NGFR,PTK2B,INA,TP53,DBN1,CAMK2G,AKT1,HUWE1,CAMK2B,BZW2,NDRG2,GSK3B,SQSTM1PAFAH1B1,CASP2,NAPA,DPYSL2,MYH10,BCL2,ARF4,NR3C1,INPPL1,SPHK2,CTNS,ATM

MED15,PAX6,HMGB2,SMARCA4,SRCAP,TAF4,SUPT5H,MED23,SNW1,CHD3,NFYC,SMARCC2,HMGB1

SF3A3,SRRM2,PRPF8,SNRNP200,SF3B3,RBM5,DDX5,SNW1,SF3B2,CRNKL1,EFTUD2,YBX1,SUGP2,DHX8

ILK,MYH10,TNFSF13B,SRRT,TP53,RAP1B,AKT1,GNB1,ZFP36L2,EGFR,EPS8,SPHK2,CUL1,USP8,CREBBP

BCL2,CAV1,PTK2B,CAPN2,ITPR1,UBQLN1,TSC2,ATP1B1,CREBBP,ATM

PAFAH1B1,MAPK1,PPP1CA,MLF1,WDR6,TP53,CREBL2,RAB11A,SUPT5H,SEPT7,KAT2B,USP9X,BECN1,GNAI2,USP8,UPF1,ARL2

ELK1,NFKB1,MAPK1,BCL2,TRAF6,CAPZA1,APP,POLR3E,TRAF3,CAPZA2,CASP1,CREBBP,HMGB1

XRCC6,SIRT1,SSRP1,DDB1,SUMO1,RAD51C,XPC,RAD23B,USP1,RECQL5,UPF1,ATM

SYMPK,FEZ1,ATP2A2,BTBD9,PTK2B,APP,NEGR1,MLLT4,CTNNB1,CDH13,CNTN1,INPPL1,RAC1,CD22,CASK,BCAN,TLN1,ENTPD1

SIRT1,MAPK1,ILK,TNFSF13B,PTK2B,DNAJA2,HDAC2,HDAC1,POU3F2,EGFR,SPHK2,GNAI2

ELK1,GRB2,CASP2,NFKB1,AP2A2,MAPK1,YWHAE,ZFYVE27,HDAC3,MTOR,TRIO,TRAF6,NGFR,MAGED1,PIK3R1,HDAC2,ITPR1,ADORA2A,AKT1,HDAC1,PDE1B,CLTC,TSC2,YWHAB,GSK3B,AP2B1,RAC1,ARHGEF6,RAPGEF1,ARHGEF7,SQSTM1,AP2A1,CASP3HIP1,CASP2,NFKB1,CASP6,PPM1F,PSMC2,TJP2,API5,YWHAE,NCKAP1,ADD1,TRIO,BCL2,TRAF6,NGFR,PTK2B,HMGB2,MAGED1,TP53,MEF2D,PSMD8,DNM1L,FNTA,ADORA2A,CTNNB1,AKT1,PDE1B,PPP1R13B,HTT,GJA1,APAF1,UBQLN1,PSMA1,NISCH,CUL1,CYFIP2,YWHAB,CASP1,TP53INP1,RAC1,ARHGEF6,CASP7,NDUFS1,GSN,ARHGEF7,SQSTM1,VDAC1,CASP3,PSMD3,HMGB1XRCC6,AP2A2,PSMC2,SLC25A4,SSRP1,RPL7,RPL23,RPL15,RPL14,RPL13,RNGTT,RANBP2,TAF4,PSMD8,NUP98,AP1B1,AP1G1,SUPT5H,TAF4B,TPR,NUP160,PSMA1,TBP,AP2B1,RAC1,NUP62,RPL6,ZNF24,RPLP2,NUP153,AP2A1,RPS6,RNMT,PSMD3GRB2,SP1,UBR4,VPRBP,SIRT1,PSMC2,MAPK1,EIF2AK2,SLC25A4,NEDD4L,YWHAE,CTBP1,DDB1,CAV1,RNGTT,NACA,SRCAP,TP53,CUL2,TAF4,PIK3R1,DYNC1I2,HSPA8,NUP98,HDAC1,KAT2B,SF3B2,CUL1,USP7,TBP,FBLN1,VDAC1,NUP153,CREBBPFLNB,PPP2R2A,NFKB1,SRGAP1,TNFRSF8,MAPK1,GRIN2A,RASD2,SRGAP2,DPYSL2,MAP3K10,DNM2,MTOR,TRAF6,BAIAP2,ARHGAP18,TNFSF13B,NGFR,PTK2B,SNX27,ZDHHC17,YWHAZ,MLLT4,CREBL2,RASA1,VAPA,PRKAA2,PIK3R1,RAP1B,CORO1C,ITPR1,NR3C1,AKT1,TRIP10,PDE1B,GNB1,CAMK2B,PI4KA,PPM1A,GJA1,TRAF1,TSC2,EGFR,EPS8,TRAF3,ARHGAP1,NDRG2,DLG4,CASP1,RAPGEF1,INPP5B,GNAI2,SH3GL3,ARHGEF7,CREBBP,ATM,OGT,PPP1R16BSGK1,HIP1,CASP2,SIRT1,PSMC2,BTG1,BCL2,TRAF6,DUSP2,MAGED1,TP53,PSMD8,CAMK1D,APAF1,TRAF1,PSMA1,TRAF3,CASP1,ACTN1,CASP3,CASP8,Casp10,PSMD3TNFRSF8,EIF2AK2,BTG1,BCL11B,CTBP1,CSK,CAV1,GDF11,PTK2B,PRKRA,WDR6,TP53,CUL2,RBM5,CTH,ADORA2A,CTNNB1,ASPH,KAT2B,GJA1,REST,CDH13,FABP3,INPPL1,TSC2,CUL1,NUP62,BECN1,BAP1GRB2,MAPK1,SIN3A,ATP2A2,CSK,CAPZA1,CAV1,CABLES1,APP,YWHAZ,TP53,PIK3R1,RAP1B,ALDOA,HDAC2,ITPR1,ADORA2A,AKT1,CAPZB,HDAC1,PDE1B,SLC16A1,GNB1,CALU,RAD51C,PPIL2,CAPZA2,RAC1,ACTN1,ATP1B1,GNAI2,TLN1,ENTPD1

PAFAH1B1,SYN1,AP2A2,NSF,MAPK1,GRIN2A,EPB41L1,VAMP2,MBP,SYT1,CACNA1E,MYO6,CAMK2G,USP14,RAB3A,GRIN1,HSPA8,STXBP1,GNB1,CAMK2B,PI4KA,KCNN3,DLG4,SNAP91,AP2B1,STX1A,GNAI2,KCNC1,SNAP25,AP2A1ELK1,TFEB,SP1,XRCC6,ZNF292,SREBF2,NFKB1,SIRT1,Ube3a,PAX6,BCL11B,NFYA,EGR1,TRAF6,LMO4,BAG1,HMGB2,CHD8,APP,MYO6,SMARCA4,TP53,MEF2D,PIK3R1,GRIN1,HDAC2,SUPT5H,CTNNB1,AKT1,HDAC1,KAT2B,CBFA2T2,ARNTL,SQSTM1,CREBBP,HMGB1SF3A3,MED15,SSRP1,RPL7,RPL23,RPL15,RPL14,RPL13,PRPF8,SNRNP200,RNGTT,SF3B3,EEF1A1,TAF4,RBM5,NR3C1,SUPT5H,TAF4B,MED23,SNW1,KAT2B,SF3B2,TBP,EFTUD2,RPL6,YBX1,RPLP2,CREBBP,RPS6,RNMT

GRB2,COL4A5,AP2A2,SRGAP1,FEZ1,MAPK1,SRGAP2,PAX6,EZR,DPYSL2,MYH10,TRIO,NGFR,STIP1,CNTN1,CLTC,EGFR,YWHAB,DLG4,MYL6,GSK3B,AP2B1,RAC1,TLN1,AP2A1

GPI,PPP1CA,PFKM,SLC2A3,B4GALT6,RANBP2,NUP98,ALDOA,AKT1,SLC25A11,TPR,NUP160,SLC25A12,PGM1,GOT1,PPP1R3D,GSK3B,NUP62,MGAT1,NUP153,SLC25A13,UGP2,GAPDH

PAFAH1B1,NDUFV1,SYN1,DYNC1H1,SLC25A3,ATP5B,FEZ1,GRIN2A,SLC25A4,SLC35F5,ATP2A2,UQCRC2,G3BP2,HDLBP,NDUFV2,CACNA1E,DYNC1I2,FADS1,AKT1,NDUFS3,SLC25A11,GJA1,CPT1B,CPT2,SORBS1,ATP6V0E1,ATP1B1,NDUFS1,NDUFB10,CTNS,NDUFA8,NDUFB8,SLC25A13SRGAP1,MYO9B,MAPK1,RASD2,SRGAP2,TRIO,ARHGAP18,ARF4,G3BP2,RAB10,RAB28,RAB3A,RAP1B,RAB11A,TRIP10,RAB14,ARHGAP1,YWHAB,RAC1,ARHGEF6,INPP5B,ARHGEF7,ARL2MECP2,XRCC6,NFKB1,SIRT1,SIN3A,MAP3K10,HDAC3,CTBP1,TRAF6,HMGB2,CHD8,SMARCA4,TP53,HSPA8,HDAC2,CTNNB1,HDAC1,SNW1,REST,SUMO1,SIN3B,YWHAB,CBFA2T2,YBX1,ZNF24,SMARCC2PAFAH1B1,FEZ1,DPYSL2,SPG7,NDUFV2,CABLES1,GDF11,INA,SMARCA4,DBN1,MEF2D,CAMK2G,FNBP1,AKT1,CAMK2B,BZW2,CAMK1D,DCTN1,APAF1,NDRG2,DLG4,GSK3B,TMOD2,ARHGEF7,SMARCC2,GSSSEC16A,NSF,COG1,ARF4,RAB10,SNX25,SNX27,ARFGAP1,NACA,VPS39,RANBP2,RAB3A,RAB11A,NUP98,STXBP1,RAB14,VPS54,TPR,CHCHD4,NUP160,SEC61A2,NUP62,SLC15A4,NXT2,VPS35,NUP153

SREBF2,GRIN2A,DPYSL2,HDAC3,BCL2,BAG1,CAV1,PTK2B,DRD1,YWHAZ,TP53,PIK3R1,ADD3,ADORA2A,CTNNB1,HADHA,SNCA,FABP3,INPPL1,XPC,ATP1A1,MAT2APAFAH1B1,DYNC1H1,PSMC2,TUBB,YWHAE,RANBP2,CEP63,DYNC1I2,PSMD8,CEP250,NUP98,NUMA1,DCTN1,TUBG1,MAD1L1,ANAPC1,NUP160,PSMA1,CUL1,BUB3,YWHAG,PSMD3

ELK1,SP1,XRCC6,NFKB1,MAPK1,PAX6,ILK,DNM2,EGR1,YWHAH,HMGB2,CHD8,SMARCA4,TP53,TAF4,USP21,HDAC2,CTNNB1,HDAC1,PPM1A,REST,TBP,NUP62,NFYC,CREBBP,SMARCC2

TFEB,SP1,HIP1,ZNF292,SFMBT2,NCOR2,BTG1,SSRP1,PAX6,BCL11B,NFYA,DNM2,ZNF207,ASXL1,LMO4,TRRAP,BATF,FLII,POU2AF1,MAGED1,SMARCA4,TP53,CREBL2,EEF1A1,MEF2D,PRKAA2,EP400,DNAJC1,HDAC2,EZH1,FADS1,NR3C1,ADORA2A,TAF4B,MED23,HDAC1,POU3F2,REST,ZFP36L2,CHD3,MAX,MYCBP2,TBP,ZNF91,RPL6,EWSR1,YBX1,PSPC1,NCOR1,NFYC,CREBBP,WHSC1,SMARCC2

MECP2,NFKB1,SIRT1,NCOR2,HDAC3,CTBP1,EGR1,TRAF6,CAV1,SMARCA4,TP53,HDAC2,EZH1,SUPT5H,CTNNB1,HDAC1,REST,YBX1,NCOR1,ZMYND8,CREBBP,WHSC1,HMGB1

CASP2,CASP6,PSMC2,CTSD,UQCRC2,SPG7,USP19,USP14,CAPN2,PSMD8,USP21,TMPRSS5,USP9X,DLD,USP1,USP7,CASP1,CASP7,USP8,UCHL3,BAP1,CASP3,CASP8,USP40

SLC41A1,SLC25A4,ATP2A2,CACNA1E,SLC2A3,RANBP2,NUP98,ITPR1,ATP6V0A1,SLC16A1,VDAC3,TPR,NUP160,SLC25A12,ABCC10,ATP1A1,NUP62,ATP6V0E1,VDAC2,ATP1B1,SLC15A4,KCNC1,VDAC1,NUP153,SLC25A13

HIP1,CASP2,NFKB1,CASP6,PPM1F,PSMC2,TJP2,API5,YWHAE,NCKAP1,ADD1,TRIO,BCL2,TRAF6,NGFR,PTK2B,HMGB2,MAGED1,TP53,MEF2D,PSMD8,DNM1L,FNTA,ADORA2A,CTNNB1,AKT1,PDE1B,PPP1R13B,HTT,GJA1,APAF1,UBQLN1,PSMA1,NISCH,CUL1,CYFIP2,YWHAB,CASP1,TP53INP1,RAC1,ARHGEF6,CASP7,NDUFS1,GSN,ARHGEF7,SQSTM1,VDAC1,CASP3,PSMD3,HMGB1

FLNB,PPP2R2A,NFKB1,SRGAP1,TNFRSF8,MAPK1,GRIN2A,RASD2,SRGAP2,DPYSL2,MAP3K10,DNM2,MTOR,TRAF6,BAIAP2,ARHGAP18,TNFSF13B,NGFR,PTK2B,SNX27,ZDHHC17,YWHAZ,MLLT4,CREBL2,RASA1,VAPA,PRKAA2,PIK3R1,RAP1B,CORO1C,ITPR1,NR3C1,AKT1,TRIP10,PDE1B,GNB1,CAMK2B,PI4KA,PPM1A,GJA1,TRAF1,TSC2,EGFR,EPS8,TRAF3,ARHGAP1,NDRG2,DLG4,CASP1,RAPGEF1,INPP5B,GNAI2,SH3GL3,ARHGEF7,CREBBP,ATM,OGT,PPP1R16B

ELK1,TFEB,SP1,XRCC6,ZNF292,SREBF2,NFKB1,SIRT1,Ube3a,PAX6,BCL11B,NFYA,EGR1,TRAF6,LMO4,BAG1,HMGB2,CHD8,APP,MYO6,SMARCA4,TP53,MEF2D,PIK3R1,GRIN1,HDAC2,SUPT5H,CTNNB1,AKT1,HDAC1,KAT2B,CBFA2T2,ARNTL,SQSTM1,CREBBP,HMGB1

PAFAH1B1,NDUFV1,SYN1,DYNC1H1,SLC25A3,ATP5B,FEZ1,GRIN2A,SLC25A4,SLC35F5,ATP2A2,UQCRC2,G3BP2,HDLBP,NDUFV2,CACNA1E,DYNC1I2,FADS1,AKT1,NDUFS3,SLC25A11,GJA1,CPT1B,CPT2,SORBS1,ATP6V0E1,ATP1B1,NDUFS1,NDUFB10,CTNS,NDUFA8,NDUFB8,SLC25A13

HIP1,CASP2,NFKB1,CASP6,PPM1F,PSMC2,TJP2,API5,YWHAE,NCKAP1,ADD1,TRIO,BCL2,TRAF6,NGFR,PTK2B,HMGB2,MAGED1,TP53,MEF2D,PSMD8,DNM1L,FNTA,ADORA2A,CTNNB1,AKT1,PDE1B,PPP1R13B,HTT,GJA1,APAF1,UBQLN1,PSMA1,NISCH,CUL1,CYFIP2,YWHAB,CASP1,TP53INP1,RAC1,ARHGEF6,CASP7,NDUFS1,GSN,ARHGEF7,SQSTM1,VDAC1,CASP3,PSMD3,HMGB1


Supplementary Table S7B: Enriched Biological pathways (KEGG) with HD associated genesId Items Items_Details

29 Kegg:05016 Huntington's disease27 Kegg:05010 Alzheimer's disease28 Kegg:05012 Parkinson's disease

1 Kegg:04722 Neurotrophin signaling pathway96 Kegg:04510 Focal adhesion50 Kegg:05200 Pathways in cancer78 Kegg:04141 Protein processing in endoplasmic32 Kegg:04810 Regulation of actin cytoskeleton85 Kegg:05152 Tuberculosis25 Kegg:00190 Oxidative phosphorylation

138 Kegg:04110 Cell cycle143 Kegg:04210 Apoptosis

38 Kegg:04010 MAPK signaling pathway113 Kegg:05215 Prostate cancer

98 Kegg:04144 Endocytosis10 Kegg:04910 Insulin signaling pathway99 Kegg:04961 Endocrine and other factor-regulat

155 Kegg:05213 Endometrial cancer153 Kegg:05100 Bacterial invasion of epithelial cell134 Kegg:04530 Tight junction116 Kegg:04114 Oocyte meiosis

69 Kegg:04020 Calcium signaling pathway4 Kegg:05160 Hepatitis C

131 Kegg:04120 Ubiquitin mediated proteolysis140 Kegg:05222 Small cell lung cancer133 Kegg:04520 Adherens junction

31 Kegg:04666 Fc gamma R-mediated phagocytos167 Kegg:05131 Shigellosis146 Kegg:05210 Colorectal cancer

46 Kegg:05145 Toxoplasmosis173 Kegg:05214 Glioma152 Kegg:04012 ErbB signaling pathway169 Kegg:05014 Amyotrophic lateral sclerosis (AL117 Kegg:04720 Long-term potentiation141 Kegg:05211 Renal cell carcinoma106 Kegg:04670 Leukocyte transendothelial migrat154 Kegg:05220 Chronic myeloid leukemia

57 Kegg:03040 Spliceosome92 Kegg:03015 mRNA surveillance pathway

107 Kegg:04310 Wnt signaling pathway63 Kegg:05162 Measles

81 Kegg:04330 Notch signaling pathway137 Kegg:05120 Epithelial cell signaling in Helicob147 Kegg:05212 Pancreatic cancer142 Kegg:04150 mTOR signaling pathway130 Kegg:04971 Gastric acid secretion105 Kegg:04662 B cell receptor signaling pathway

26 Kegg:04260 Cardiac muscle contraction144 Kegg:05142 Chagas disease (American trypano

58 Kegg:04062 Chemokine signaling pathway115 Kegg:04960 Aldosterone-regulated sodium reab

6 Kegg:00010 Glycolysis / Gluconeogenesis77 Kegg:03010 Ribosome

118 Kegg:04962 Vasopressin-regulated water reabs3 Kegg:03013 RNA transport

44 Kegg:04912 GnRH signaling pathway129 Kegg:04916 Melanogenesis150 Kegg:04380 Osteoclast differentiation

51 Kegg:05223 Non-small cell lung cancer60 Kegg:04620 Toll-like receptor signaling pathw

7 Kegg:00270 Cysteine and methionine metaboli168 Kegg:05221 Acute myeloid leukemia126 Kegg:04540 Gap junction170 Kegg:05416 Viral myocarditis110 Kegg:04115 p53 signaling pathway

16 Kegg:04142 Lysosome66 Kegg:03320 PPAR signaling pathway

121 Kegg:00030 Pentose phosphate pathway45 Kegg:04972 Pancreatic secretion30 Kegg:04360 Axon guidance

175 Kegg:05216 Thyroid cancer93 Kegg:05412 Arrhythmogenic right ventricular

101 Kegg:05110 Vibrio cholerae infection103 Kegg:05130 Pathogenic Escherichia coli infect149 Kegg:04612 Antigen processing and presentati159 Kegg:05020 Prion diseases

19 Kegg:04621 NOD-like receptor signaling path128 Kegg:04914 Progesterone-mediated oocyte mat177 Kegg:00400 Phenylalanine, tyrosine and trypto

17 Kegg:00230 Purine metabolism42 Kegg:04724 Glutamatergic synapse

164 Kegg:04973 Carbohydrate digestion and absorp11 Kegg:04920 Adipocytokine signaling pathway43 Kegg:04730 Long-term depression

61 Kegg:04622 RIG-I-like receptor signaling path119 Kegg:05218 Melanoma

49 Kegg:04320 Dorso-ventral axis formation67 Kegg:04145 Phagosome

112 Kegg:04930 Type II diabetes mellitus40 Kegg:04370 VEGF signaling pathway70 Kegg:04070 Phosphatidylinositol signaling sys

104 Kegg:04660 T cell receptor signaling pathway52 Kegg:00520 Amino sugar and nucleotide sugar41 Kegg:04664 Fc epsilon RI signaling pathway

123 Kegg:00052 Galactose metabolism12 Kegg:05410 Hypertrophic cardiomyopathy (H

148 Kegg:04350 TGF-beta signaling pathway156 Kegg:05217 Basal cell carcinoma

9 Kegg:00640 Propanoate metabolism79 Kegg:00260 Glycine, serine and threonine met84 Kegg:04650 Natural killer cell mediated cytotox62 Kegg:04623 Cytosolic DNA-sensing pathway64 Kegg:04130 SNARE interactions in vesicular tr

122 Kegg:00051 Fructose and mannose metabolism139 Kegg:05140 Leishmaniasis160 Kegg:05146 Amoebiasis

8 Kegg:00620 Pyruvate metabolism35 Kegg:03022 Basal transcription factors71 Kegg:00600 Sphingolipid metabolism

132 Kegg:03050 Proteasome20 Kegg:00071 Fatty acid metabolism56 Kegg:03420 Nucleotide excision repair54 Kegg:00360 Phenylalanine metabolism

135 Kegg:05219 Bladder cancer

Supplementary Table S7B: Enriched Biological pathways (KEGG) with HD associated genesSupport List size Reference Support Reference size

43 518 180 3420828 518 163 3420823 518 129 3420822 518 124 3420822 518 197 3420827 518 324 3420819 518 159 3420820 518 209 3420818 518 172 3420816 518 130 3420815 518 123 3420813 518 86 3420821 518 262 3420813 518 88 3420818 518 193 3420815 518 133 3420810 518 49 3420810 518 52 3420811 518 70 3420814 518 130 3420813 518 110 3420816 518 175 3420814 518 133 3420814 518 135 3420811 518 84 3420810 518 71 3420811 518 92 34208

9 518 61 342089 518 62 34208

12 518 123 342089 518 63 34208

10 518 87 342088 518 50 342089 518 68 342089 518 70 34208

11 518 113 342089 518 73 34208

11 518 118 342089 518 79 34208

12 518 149 3420811 518 130 34208

7 518 46 342088 518 67 342088 518 70 342087 518 52 342088 518 72 342088 518 75 342088 518 76 342089 518 102 34208

12 518 186 342086 518 42 342087 518 62 342088 518 86 342086 518 44 34208

10 518 145 342088 518 98 342088 518 98 342089 518 126 342086 518 53 342088 518 101 342085 518 36 342086 518 57 342087 518 88 342086 518 63 342086 518 67 342088 518 121 342086 518 70 342084 518 27 342087 518 98 342088 518 128 342084 518 28 342086 518 73 342085 518 53 342085 518 54 342085 518 56 342084 518 34 342085 518 57 342086 518 86 342082 518 5 342088 518 158 342087 518 124 342084 518 41 342085 518 67 342085 518 69 34208

5 518 70 342085 518 70 342083 518 23 342087 518 137 342084 518 46 342085 518 75 342085 518 76 342086 518 107 342084 518 48 342085 518 77 342083 518 27 342085 518 82 342085 518 82 342084 518 55 342083 518 32 342083 518 32 342086 518 125 342084 518 60 342083 518 35 342083 518 36 342084 518 66 342085 518 102 342083 518 39 342083 518 39 342083 518 40 342083 518 40 342083 518 41 342083 518 41 342082 518 16 342083 518 42 34208

Hyp Hyp_c Genes9.73E-39 1.74E-36 APAF1,DCTN1,DLG4,DNALI1,COX4I1,NDUFA8,CLTC,ATP5A1,VDAC2,VDAC1,SIN3A,NDUFV2,ATP5F1,CASP8,NDUFB10,NDUFV1,AP2A2,TGM2,SLC25A4,CASP3,TBP,UQCRC2,ATP5C1,GRIN1,AP2B1,NDUFS1,HIP1,HDAC1,CREBBP,TP53,ITPR1,COX6C,TAF4,REST,HDAC2,HTT,NDUFS3,SP1,VDAC3,NDUFB8,ATP5B,AP2A1,TAF4B1.99E-21 1.78E-19 APAF1,GSK3B,COX4I1,NDUFA8,MAPK1,ATP2A2,ATP5A1,CASP7,NDUFV2,ATP5F1,SNCA,CASP8,NDUFB10,NDUFV1,CAPN2,CASP3,UQCRC2,ATP5C1,GRIN1,APP,GRIN2A,NDUFS1,GAPDH,ITPR1,COX6C,NDUFS3,NDUFB8,ATP5B3.27E-18 1.95E-16 APAF1,COX4I1,NDUFA8,ATP5A1,VDAC2,VDAC1,NDUFV2,PARK2,ATP5F1,SNCA,UBA1,NDUFB10,NDUFV1,SLC25A4,CASP3,UQCRC2,ATP5C1,NDUFS1,COX6C,NDUFS3,VDAC3,NDUFB8,ATP5B1.98E-17 8.85E-16 GSK3B,MAPK1,YWHAH,CAMK2B,YWHAZ,MAGED1,GRB2,YWHAE,RAP1B,CSK,TRAF6,AKT1,YWHAG,NFKB1,PIK3R1,NGFR,BCL2,RAC1,YWHAB,CAMK2G,TP53,RAPGEF14.05E-13 1.45E-11 GSK3B,MAPK1,ACTN1,COL4A5,DIAPH1,GRB2,TLN1,RAP1B,ACTB,CAPN2,CAV1,AKT1,EGFR,PIK3R1,BCL2,PPP1CA,RAC1,ILK,CTNNB1,ELK1,RAPGEF1,FLNB1.08E-12 3.22E-11 WNT10A,MTOR,GSK3B,MAPK1,CUL2,MAX,COL4A5,CASP8,GRB2,TPR,TRAF6,CTBP1,AKT1,EGFR,CASP3,NFKB1,GSTP1,PIK3R1,BCL2,RAC1,TRAF3,HDAC1,CTNNB1,CREBBP,TP53,TRAF1,HDAC24.87E-12 1.25E-10 SEC24C,EIF2AK2,SEC23A,PARK2,DNAJA2,UBE2D2,BAG1,DNAJB1,DNAJC1,CAPN2,HSPA2,SEC61A2,BCL2,CUL1,UBQLN2,DNAJA1,RAD23B,UBQLN1,HSPA88.10E-11 1.81E-09 ARHGEF7,ARHGEF6,MAPK1,ACTN1,PFN2,EZR,MYH10,DIAPH1,NCKAP1,GSN,ACTB,CSK,ARPC1A,EGFR,PIK3R1,PPP1CA,RAC1,BAIAP2,CYFIP2,GIT11.65E-10 2.95E-09 APAF1,MAPK1,CAMK2B,CTSD,NFYA,CASP8,Casp10,SPHK2,ATP6V0A1,TRAF6,AKT1,CASP3,NFKB1,BCL2,CAMK2G,CREBBP,NFYC,HSPA91.51E-10 3.01E-09 COX4I1,NDUFA8,ATP5A1,NDUFV2,ATP5F1,ATP6V0A1,NDUFB10,NDUFV1,ATP6V0E1,UQCRC2,ATP5C1,NDUFS1,COX6C,NDUFS3,NDUFB8,ATP5B6.47E-10 9.65E-09 GSK3B,YWHAH,YWHAZ,ANAPC1,BUB3,YWHAE,YWHAG,CUL1,YWHAB,HDAC1,CREBBP,MAD1L1,TP53,HDAC2,ATM6.03E-10 9.81E-09 APAF1,CASP6,CASP7,CASP8,Casp10,CAPN2,AKT1,CASP3,NFKB1,PIK3R1,BCL2,TP53,ATM7.33E-10 1.01E-08 CACNA2D1,MAPK1,DUSP8,CACNA1E,MAX,GRB2,PPM1A,RAP1B,TRAF6,AKT1,EGFR,CASP3,NFKB1,HSPA2,RAC1,RASA1,TP53,ELK1,DUSP2,HSPA8,FLNB8.09E-10 1.03E-08 MTOR,GSK3B,MAPK1,GRB2,AKT1,EGFR,NFKB1,GSTP1,PIK3R1,BCL2,CTNNB1,CREBBP,TP531.08E-09 1.29E-08 USP8,CLTC,DNM1,RAB11A,DNM2,NEDD4L,AP2A2,DNM1L,CAV1,TRAF6,EGFR,HSPA2,SH3GL3,ARFGAP1,AP2B1,HSPA8,GIT1,AP2A11.95E-09 2.18E-08 MTOR,GSK3B,MAPK1,GRB2,PPP1R3D,AKT1,TRIP10,PIK3R1,RPS6,TSC2,PPP1CA,PRKAA2,SORBS1,ELK1,RAPGEF12.82E-09 2.96E-08 ATP1B1,CLTC,DNM1,RAB11A,DNM2,ATP1A1,AP2A2,DNM1L,AP2B1,AP2A15.20E-09 5.17E-08 GSK3B,MAPK1,GRB2,AKT1,EGFR,PIK3R1,ILK,CTNNB1,TP53,ELK18.35E-09 7.87E-08 CLTC,DNM1,DNM2,ACTB,DNM1L,CAV1,ARPC1A,PIK3R1,RAC1,ILK,CTNNB11.23E-08 1.05E-07 ACTN1,TJP2,MLLT4,MYH10,PPP2R2A,PPP2R1B,EPB41L1,ACTB,AKT1,GNAI2,CTNNB1,SYMPK,CASK,VAPA1.32E-08 1.07E-07 MAPK1,YWHAH,CAMK2B,YWHAZ,ANAPC1,PPP2R1B,YWHAE,YWHAG,PPP1CA,CUL1,YWHAB,CAMK2G,ITPR11.22E-08 1.09E-07 CAMK2B,ATP2A2,VDAC2,CACNA1E,PTK2B,VDAC1,SPHK2,SLC25A4,EGFR,GRIN1,GRIN2A,CAMK2G,ITPR1,PDE1B,DRD1,VDAC31.65E-08 1.29E-07 GSK3B,MAPK1,EIF2AK2,TYK2,GRB2,PPP2R2A,PPP2R1B,TRAF6,AKT1,EGFR,NFKB1,PIK3R1,TRAF3,TP532.00E-08 1.50E-07 CUL2,ANAPC1,PARK2,DDB1,UBA1,UBE2D2,Ube3a,UBE2K,NEDD4L,TRAF6,UBE2H,CUL1,HUWE1,PPIL25.93E-08 4.24E-07 APAF1,MAX,COL4A5,TRAF6,AKT1,NFKB1,PIK3R1,BCL2,TRAF3,TP53,TRAF11.17E-07 8.09E-07 MAPK1,ACTN1,MLLT4,ACTB,EGFR,RAC1,BAIAP2,CTNNB1,CREBBP,SORBS11.54E-07 1.02E-06 MAPK1,MARCKS,DNM1,DNM2,SPHK2,GSN,DNM1L,ARPC1A,AKT1,PIK3R1,RAC13.37E-07 2.15E-06 MAPK1,PFN2,DIAPH1,UBE2D2,ACTB,CSK,ARPC1A,NFKB1,RAC13.89E-07 2.40E-06 GSK3B,MAPK1,AKT1,CASP3,PIK3R1,BCL2,RAC1,CTNNB1,TP534.02E-07 2.40E-06 MAPK1,CASP8,TYK2,TRAF6,AKT1,CASP3,NFKB1,PIK3R1,GNAI2,HSPA2,BCL2,HSPA84.48E-07 2.58E-06 MTOR,MAPK1,CAMK2B,GRB2,AKT1,EGFR,PIK3R1,CAMK2G,TP538.20E-07 4.45E-06 MTOR,GSK3B,MAPK1,CAMK2B,GRB2,AKT1,EGFR,PIK3R1,CAMK2G,ELK18.05E-07 4.50E-06 APAF1,CASP1,CASP3,BCL2,GRIN1,RAC1,GRIN2A,TP538.71E-07 4.59E-06 MAPK1,CAMK2B,RAP1B,GRIN1,PPP1CA,GRIN2A,CAMK2G,CREBBP,ITPR11.12E-06 5.73E-06 MAPK1,CUL2,GRB2,RAP1B,AKT1,PIK3R1,RAC1,CREBBP,RAPGEF11.25E-06 6.22E-06 ACTN1,PTK2B,MLLT4,EZR,RAP1B,ACTB,PIK3R1,GNAI2,RAC1,CTNNB1,THY11.61E-06 7.77E-06 MAPK1,GRB2,CTBP1,AKT1,NFKB1,PIK3R1,HDAC1,TP53,HDAC21.92E-06 9.06E-06 SF3A3,SNRNP200,PRPF8,SF3B3,HSPA2,EFTUD2,SNW1,CRNKL1,HSPA8,DHX8,SF3B23.14E-06 1.41E-05 SMG5,GSPT1,PPP2R2A,NXT2,RNMT,PPP2R1B,RNGTT,SYMPK,UPF13.11E-06 1.43E-05 WNT10A,GSK3B,CAMK2B,CHD8,PPP2R1B,CTBP1,RAC1,CUL1,CAMK2G,CTNNB1,CREBBP,TP534.96E-06 2.17E-05 GSK3B,EIF2AK2,TYK2,TRAF6,AKT1,NFKB1,PIK3R1,HSPA2,TP53,ADAR,HSPA8

5.63E-06 2.40E-05 KAT2B,CTBP1,SNW1,NCOR2,HDAC1,CREBBP,HDAC27.80E-06 3.25E-05 ATP6V0A1,ATP6V0E1,CSK,EGFR,CASP3,NFKB1,RAC1,GIT11.09E-05 4.42E-05 ARHGEF6,MAPK1,AKT1,EGFR,NFKB1,PIK3R1,RAC1,TP531.30E-05 5.18E-05 MTOR,MAPK1,AKT1,PIK3R1,RPS6,TSC2,PRKAA21.34E-05 5.22E-05 ATP1B1,CAMK2B,EZR,ATP1A1,ACTB,GNAI2,CAMK2G,ITPR11.82E-05 6.92E-05 GSK3B,CD22,MAPK1,GRB2,AKT1,NFKB1,PIK3R1,RAC12.00E-05 7.47E-05 ATP1B1,TPM2,CACNA2D1,COX4I1,ATP2A2,ATP1A1,UQCRC2,COX6C2.57E-05 9.39E-05 MAPK1,CASP8,PPP2R2A,PPP2R1B,TRAF6,AKT1,NFKB1,PIK3R1,GNAI22.95E-05 0.000105786 GSK3B,MAPK1,PTK2B,GNB1,GRB2,RAP1B,CSK,AKT1,NFKB1,PIK3R1,GNAI2,RAC13.87E-05 0.000135789 ATP1B1,SGK1,MAPK1,ATP1A1,NEDD4L,PIK3R14.20E-05 0.000144529 DLD,GPI,LDHA,ALDOA,PGM1,GAPDH,PFKM4.94E-05 0.000166863 RPL13,RPL15,RPLP2,RPL6,RPL7,RPL23,RPS6,RPL145.07E-05 0.000168216 DCTN1,RAB11A,VAMP2,DYNC1H1,DYNC1I2,NSF7.74E-05 0.000251977 RANBP2,NUP98,NXT2,EEF1A1,TPR,NUP62,SUMO1,NUP153,NUP160,UPF1

0.000125115 0.000392905 MAPK1,CAMK2B,PTK2B,GRB2,EGFR,CAMK2G,ITPR1,ELK10.000125115 0.000392905 WNT10A,GSK3B,MAPK1,CAMK2B,GNAI2,CAMK2G,CTNNB1,CREBBP0.000134337 0.000414593 MAPK1,TYK2,SQSTM1,GRB2,TRAF6,AKT1,NFKB1,PIK3R1,RAC10.000147117 0.000446337 MAPK1,GRB2,AKT1,EGFR,PIK3R1,TP530.000154463 0.000460814 MAPK1,CASP8,TRAF6,AKT1,NFKB1,PIK3R1,RAC1,TRAF30.000199807 0.000586319 CTH,MAT2A,LDHA,GOT1,CBS0.000220981 0.000637995 MTOR,MAPK1,GRB2,AKT1,NFKB1,PIK3R10.000386748 0.00108168 MAPK1,GRB2,EGFR,GNAI2,ITPR1,DRD1,GJA10.000383334 0.00108916 CASP8,MYH10,ACTB,CAV1,CASP3,RAC10.000535112 0.00145129 APAF1,CASP8,CASP3,TSC2,TP53,ATM0.000528969 0.0014567 GGA3,CLTC,CTSD,ATP6V0A1,AP1G1,AP1B1,CTNS,AP3D10.000676774 0.0018081 FABP5,CPT2,ILK,CPT1B,SORBS1,FABP30.000691776 0.001821 GPI,ALDOA,PGM1,PFKM0.000740621 0.00192132 ATP1B1,ATP2A2,RAB11A,ATP1A1,RAP1B,RAC1,ITPR10.000766961 0.00196123 GSK3B,MAPK1,SRGAP1,DPYSL2,GNAI2,RAC1,RASA1,SRGAP20.000797481 0.00201055 MAPK1,TPR,CTNNB1,TP530.000845852 0.00210288 CACNA2D1,ATP2A2,ACTN1,ACTB,CTNNB1,GJA1

0.00123182 0.00302049 TJP2,ATP6V0A1,ATP6V0E1,ACTB,SEC61A20.00134084 0.00324339 YWHAZ,EZR,ACTB,ARPC1A,CTNNB10.00158001 0.00377096 HSPA4,NFYA,HSPA2,NFYC,HSPA80.00168149 0.00396035 MAPK1,EGR1,STIP1,ELK10.00171069 0.00397679 MAPK1,CASP1,CASP8,TRAF6,NFKB10.00198171 0.00454777 MAPK1,ANAPC1,AKT1,PIK3R1,GNAI2,MAD1L10.00222037 0.00503096 GOT1,PAH0.00291879 0.00645016 ENTPD6,PGM1,ENTPD2,ENTPD1,ENTPD3,PAICS,PDE1B,POLR3E0.00288392 0.00645278 DLG4,MAPK1,GNB1,GNAI2,GRIN1,GRIN2A,ITPR10.00337854 0.00737511 ATP1B1,ATP1A1,AKT1,PIK3R10.00348847 0.00752333 MTOR,AKT1,NFKB1,PRKAA2,CPT1B0.00396096 0.00844062 MAPK1,PPP2R1B,GNAI2,ITPR1,GNAZ

0.00421359 0.00877015 CASP8,Casp10,TRAF6,NFKB1,TRAF30.00421359 0.00877015 MAPK1,AKT1,EGFR,PIK3R1,TP530.00487989 0.0100402 MAPK1,GRB2,EGFR0.00498894 0.010148 ATP6V0A1,ATP6V0E1,DYNC1H1,ACTB,SEC61A2,RAC1,DYNC1I20.00513086 0.0103194 MTOR,MAPK1,CACNA1E,PIK3R10.00565136 0.0112399 MAPK1,SPHK2,AKT1,PIK3R1,RAC10.0059757 0.0115016 INPP5B,INPPL1,PI4KA,PIK3R1,ITPR1

0.00584793 0.0115031 GSK3B,MAPK1,GRB2,AKT1,NFKB1,PIK3R10.00597492 0.0116251 GMDS,GPI,UGP2,PGM10.00631291 0.0120214 MAPK1,GRB2,AKT1,PIK3R1,RAC10.00770748 0.0145225 UGP2,PGM1,PFKM0.00820101 0.0151338 TPM2,CACNA2D1,ATP2A2,ACTB,PRKAA20.00820101 0.0151338 MAPK1,PPP2R1B,CUL1,CREBBP,SP10.0096424 0.0176121 WNT10A,GSK3B,CTNNB1,TP530.0123623 0.0219095 LDHA,SUCLA2,HADHA0.0123623 0.0219095 DLD,CTH,CBS0.0121183 0.0219108 MAPK1,PTK2B,GRB2,CASP3,PIK3R1,RAC10.0129993 0.0228125 CASP1,NFKB1,ADAR,POLR3E0.0157788 0.0274214 SNAP25,VAMP2,STX1A0.0170237 0.0293004 GMDS,ALDOA,PFKM

0.017908 0.0305288 MAPK1,TRAF6,NFKB1,ELK10.0196294 0.0331478 ACTN1,COL4A5,CASP3,NFKB1,PIK3R10.0210789 0.0349363 DLD,LDHA,ME20.0210789 0.0349363 TBP,TAF4,TAF4B0.0225378 0.0366752 SGPP2,SPHK2,B4GALT60.0225378 0.0366752 PSMD3,PSMC2,PSMD80.0240504 0.0380975 CPT2,CPT1B,HADHA0.0240504 0.0380975 DDB1,XPC,RAD23B0.0238676 0.0384892 GOT1,PAH0.0256166 0.0402225 MAPK1,EGFR,TP53

APAF1,DCTN1,DLG4,DNALI1,COX4I1,NDUFA8,CLTC,ATP5A1,VDAC2,VDAC1,SIN3A,NDUFV2,ATP5F1,CASP8,NDUFB10,NDUFV1,AP2A2,TGM2,SLC25A4,CASP3,TBP,UQCRC2,ATP5C1,GRIN1,AP2B1,NDUFS1,HIP1,HDAC1,CREBBP,TP53,ITPR1,COX6C,TAF4,REST,HDAC2,HTT,NDUFS3,SP1,VDAC3,NDUFB8,ATP5B,AP2A1,TAF4BAPAF1,GSK3B,COX4I1,NDUFA8,MAPK1,ATP2A2,ATP5A1,CASP7,NDUFV2,ATP5F1,SNCA,CASP8,NDUFB10,NDUFV1,CAPN2,CASP3,UQCRC2,ATP5C1,GRIN1,APP,GRIN2A,NDUFS1,GAPDH,ITPR1,COX6C,NDUFS3,NDUFB8,ATP5BAPAF1,COX4I1,NDUFA8,ATP5A1,VDAC2,VDAC1,NDUFV2,PARK2,ATP5F1,SNCA,UBA1,NDUFB10,NDUFV1,SLC25A4,CASP3,UQCRC2,ATP5C1,NDUFS1,COX6C,NDUFS3,VDAC3,NDUFB8,ATP5BGSK3B,MAPK1,YWHAH,CAMK2B,YWHAZ,MAGED1,GRB2,YWHAE,RAP1B,CSK,TRAF6,AKT1,YWHAG,NFKB1,PIK3R1,NGFR,BCL2,RAC1,YWHAB,CAMK2G,TP53,RAPGEF1GSK3B,MAPK1,ACTN1,COL4A5,DIAPH1,GRB2,TLN1,RAP1B,ACTB,CAPN2,CAV1,AKT1,EGFR,PIK3R1,BCL2,PPP1CA,RAC1,ILK,CTNNB1,ELK1,RAPGEF1,FLNBWNT10A,MTOR,GSK3B,MAPK1,CUL2,MAX,COL4A5,CASP8,GRB2,TPR,TRAF6,CTBP1,AKT1,EGFR,CASP3,NFKB1,GSTP1,PIK3R1,BCL2,RAC1,TRAF3,HDAC1,CTNNB1,CREBBP,TP53,TRAF1,HDAC2SEC24C,EIF2AK2,SEC23A,PARK2,DNAJA2,UBE2D2,BAG1,DNAJB1,DNAJC1,CAPN2,HSPA2,SEC61A2,BCL2,CUL1,UBQLN2,DNAJA1,RAD23B,UBQLN1,HSPA8ARHGEF7,ARHGEF6,MAPK1,ACTN1,PFN2,EZR,MYH10,DIAPH1,NCKAP1,GSN,ACTB,CSK,ARPC1A,EGFR,PIK3R1,PPP1CA,RAC1,BAIAP2,CYFIP2,GIT1APAF1,MAPK1,CAMK2B,CTSD,NFYA,CASP8,Casp10,SPHK2,ATP6V0A1,TRAF6,AKT1,CASP3,NFKB1,BCL2,CAMK2G,CREBBP,NFYC,HSPA9COX4I1,NDUFA8,ATP5A1,NDUFV2,ATP5F1,ATP6V0A1,NDUFB10,NDUFV1,ATP6V0E1,UQCRC2,ATP5C1,NDUFS1,COX6C,NDUFS3,NDUFB8,ATP5BGSK3B,YWHAH,YWHAZ,ANAPC1,BUB3,YWHAE,YWHAG,CUL1,YWHAB,HDAC1,CREBBP,MAD1L1,TP53,HDAC2,ATMAPAF1,CASP6,CASP7,CASP8,Casp10,CAPN2,AKT1,CASP3,NFKB1,PIK3R1,BCL2,TP53,ATMCACNA2D1,MAPK1,DUSP8,CACNA1E,MAX,GRB2,PPM1A,RAP1B,TRAF6,AKT1,EGFR,CASP3,NFKB1,HSPA2,RAC1,RASA1,TP53,ELK1,DUSP2,HSPA8,FLNBMTOR,GSK3B,MAPK1,GRB2,AKT1,EGFR,NFKB1,GSTP1,PIK3R1,BCL2,CTNNB1,CREBBP,TP53USP8,CLTC,DNM1,RAB11A,DNM2,NEDD4L,AP2A2,DNM1L,CAV1,TRAF6,EGFR,HSPA2,SH3GL3,ARFGAP1,AP2B1,HSPA8,GIT1,AP2A1MTOR,GSK3B,MAPK1,GRB2,PPP1R3D,AKT1,TRIP10,PIK3R1,RPS6,TSC2,PPP1CA,PRKAA2,SORBS1,ELK1,RAPGEF1ATP1B1,CLTC,DNM1,RAB11A,DNM2,ATP1A1,AP2A2,DNM1L,AP2B1,AP2A1GSK3B,MAPK1,GRB2,AKT1,EGFR,PIK3R1,ILK,CTNNB1,TP53,ELK1CLTC,DNM1,DNM2,ACTB,DNM1L,CAV1,ARPC1A,PIK3R1,RAC1,ILK,CTNNB1ACTN1,TJP2,MLLT4,MYH10,PPP2R2A,PPP2R1B,EPB41L1,ACTB,AKT1,GNAI2,CTNNB1,SYMPK,CASK,VAPAMAPK1,YWHAH,CAMK2B,YWHAZ,ANAPC1,PPP2R1B,YWHAE,YWHAG,PPP1CA,CUL1,YWHAB,CAMK2G,ITPR1CAMK2B,ATP2A2,VDAC2,CACNA1E,PTK2B,VDAC1,SPHK2,SLC25A4,EGFR,GRIN1,GRIN2A,CAMK2G,ITPR1,PDE1B,DRD1,VDAC3GSK3B,MAPK1,EIF2AK2,TYK2,GRB2,PPP2R2A,PPP2R1B,TRAF6,AKT1,EGFR,NFKB1,PIK3R1,TRAF3,TP53CUL2,ANAPC1,PARK2,DDB1,UBA1,UBE2D2,Ube3a,UBE2K,NEDD4L,TRAF6,UBE2H,CUL1,HUWE1,PPIL2APAF1,MAX,COL4A5,TRAF6,AKT1,NFKB1,PIK3R1,BCL2,TRAF3,TP53,TRAF1MAPK1,ACTN1,MLLT4,ACTB,EGFR,RAC1,BAIAP2,CTNNB1,CREBBP,SORBS1MAPK1,MARCKS,DNM1,DNM2,SPHK2,GSN,DNM1L,ARPC1A,AKT1,PIK3R1,RAC1MAPK1,PFN2,DIAPH1,UBE2D2,ACTB,CSK,ARPC1A,NFKB1,RAC1GSK3B,MAPK1,AKT1,CASP3,PIK3R1,BCL2,RAC1,CTNNB1,TP53MAPK1,CASP8,TYK2,TRAF6,AKT1,CASP3,NFKB1,PIK3R1,GNAI2,HSPA2,BCL2,HSPA8MTOR,MAPK1,CAMK2B,GRB2,AKT1,EGFR,PIK3R1,CAMK2G,TP53MTOR,GSK3B,MAPK1,CAMK2B,GRB2,AKT1,EGFR,PIK3R1,CAMK2G,ELK1APAF1,CASP1,CASP3,BCL2,GRIN1,RAC1,GRIN2A,TP53MAPK1,CAMK2B,RAP1B,GRIN1,PPP1CA,GRIN2A,CAMK2G,CREBBP,ITPR1MAPK1,CUL2,GRB2,RAP1B,AKT1,PIK3R1,RAC1,CREBBP,RAPGEF1ACTN1,PTK2B,MLLT4,EZR,RAP1B,ACTB,PIK3R1,GNAI2,RAC1,CTNNB1,THY1MAPK1,GRB2,CTBP1,AKT1,NFKB1,PIK3R1,HDAC1,TP53,HDAC2SF3A3,SNRNP200,PRPF8,SF3B3,HSPA2,EFTUD2,SNW1,CRNKL1,HSPA8,DHX8,SF3B2SMG5,GSPT1,PPP2R2A,NXT2,RNMT,PPP2R1B,RNGTT,SYMPK,UPF1WNT10A,GSK3B,CAMK2B,CHD8,PPP2R1B,CTBP1,RAC1,CUL1,CAMK2G,CTNNB1,CREBBP,TP53GSK3B,EIF2AK2,TYK2,TRAF6,AKT1,NFKB1,PIK3R1,HSPA2,TP53,ADAR,HSPA8

KAT2B,CTBP1,SNW1,NCOR2,HDAC1,CREBBP,HDAC2ATP6V0A1,ATP6V0E1,CSK,EGFR,CASP3,NFKB1,RAC1,GIT1ARHGEF6,MAPK1,AKT1,EGFR,NFKB1,PIK3R1,RAC1,TP53MTOR,MAPK1,AKT1,PIK3R1,RPS6,TSC2,PRKAA2ATP1B1,CAMK2B,EZR,ATP1A1,ACTB,GNAI2,CAMK2G,ITPR1GSK3B,CD22,MAPK1,GRB2,AKT1,NFKB1,PIK3R1,RAC1ATP1B1,TPM2,CACNA2D1,COX4I1,ATP2A2,ATP1A1,UQCRC2,COX6CMAPK1,CASP8,PPP2R2A,PPP2R1B,TRAF6,AKT1,NFKB1,PIK3R1,GNAI2GSK3B,MAPK1,PTK2B,GNB1,GRB2,RAP1B,CSK,AKT1,NFKB1,PIK3R1,GNAI2,RAC1ATP1B1,SGK1,MAPK1,ATP1A1,NEDD4L,PIK3R1DLD,GPI,LDHA,ALDOA,PGM1,GAPDH,PFKMRPL13,RPL15,RPLP2,RPL6,RPL7,RPL23,RPS6,RPL14DCTN1,RAB11A,VAMP2,DYNC1H1,DYNC1I2,NSFRANBP2,NUP98,NXT2,EEF1A1,TPR,NUP62,SUMO1,NUP153,NUP160,UPF1MAPK1,CAMK2B,PTK2B,GRB2,EGFR,CAMK2G,ITPR1,ELK1WNT10A,GSK3B,MAPK1,CAMK2B,GNAI2,CAMK2G,CTNNB1,CREBBPMAPK1,TYK2,SQSTM1,GRB2,TRAF6,AKT1,NFKB1,PIK3R1,RAC1

MAPK1,CASP8,TRAF6,AKT1,NFKB1,PIK3R1,RAC1,TRAF3

MAPK1,GRB2,EGFR,GNAI2,ITPR1,DRD1,GJA1

GGA3,CLTC,CTSD,ATP6V0A1,AP1G1,AP1B1,CTNS,AP3D1

ATP1B1,ATP2A2,RAB11A,ATP1A1,RAP1B,RAC1,ITPR1GSK3B,MAPK1,SRGAP1,DPYSL2,GNAI2,RAC1,RASA1,SRGAP2

CACNA2D1,ATP2A2,ACTN1,ACTB,CTNNB1,GJA1TJP2,ATP6V0A1,ATP6V0E1,ACTB,SEC61A2

MAPK1,ANAPC1,AKT1,PIK3R1,GNAI2,MAD1L1

ENTPD6,PGM1,ENTPD2,ENTPD1,ENTPD3,PAICS,PDE1B,POLR3EDLG4,MAPK1,GNB1,GNAI2,GRIN1,GRIN2A,ITPR1

ATP6V0A1,ATP6V0E1,DYNC1H1,ACTB,SEC61A2,RAC1,DYNC1I2

GSK3B,MAPK1,GRB2,AKT1,NFKB1,PIK3R1

APAF1,DCTN1,DLG4,DNALI1,COX4I1,NDUFA8,CLTC,ATP5A1,VDAC2,VDAC1,SIN3A,NDUFV2,ATP5F1,CASP8,NDUFB10,NDUFV1,AP2A2,TGM2,SLC25A4,CASP3,TBP,UQCRC2,ATP5C1,GRIN1,AP2B1,NDUFS1,HIP1,HDAC1,CREBBP,TP53,ITPR1,COX6C,TAF4,REST,HDAC2,HTT,NDUFS3,SP1,VDAC3,NDUFB8,ATP5B,AP2A1,TAF4BAPAF1,GSK3B,COX4I1,NDUFA8,MAPK1,ATP2A2,ATP5A1,CASP7,NDUFV2,ATP5F1,SNCA,CASP8,NDUFB10,NDUFV1,CAPN2,CASP3,UQCRC2,ATP5C1,GRIN1,APP,GRIN2A,NDUFS1,GAPDH,ITPR1,COX6C,NDUFS3,NDUFB8,ATP5BAPAF1,COX4I1,NDUFA8,ATP5A1,VDAC2,VDAC1,NDUFV2,PARK2,ATP5F1,SNCA,UBA1,NDUFB10,NDUFV1,SLC25A4,CASP3,UQCRC2,ATP5C1,NDUFS1,COX6C,NDUFS3,VDAC3,NDUFB8,ATP5BGSK3B,MAPK1,YWHAH,CAMK2B,YWHAZ,MAGED1,GRB2,YWHAE,RAP1B,CSK,TRAF6,AKT1,YWHAG,NFKB1,PIK3R1,NGFR,BCL2,RAC1,YWHAB,CAMK2G,TP53,RAPGEF1GSK3B,MAPK1,ACTN1,COL4A5,DIAPH1,GRB2,TLN1,RAP1B,ACTB,CAPN2,CAV1,AKT1,EGFR,PIK3R1,BCL2,PPP1CA,RAC1,ILK,CTNNB1,ELK1,RAPGEF1,FLNBWNT10A,MTOR,GSK3B,MAPK1,CUL2,MAX,COL4A5,CASP8,GRB2,TPR,TRAF6,CTBP1,AKT1,EGFR,CASP3,NFKB1,GSTP1,PIK3R1,BCL2,RAC1,TRAF3,HDAC1,CTNNB1,CREBBP,TP53,TRAF1,HDAC2SEC24C,EIF2AK2,SEC23A,PARK2,DNAJA2,UBE2D2,BAG1,DNAJB1,DNAJC1,CAPN2,HSPA2,SEC61A2,BCL2,CUL1,UBQLN2,DNAJA1,RAD23B,UBQLN1,HSPA8ARHGEF7,ARHGEF6,MAPK1,ACTN1,PFN2,EZR,MYH10,DIAPH1,NCKAP1,GSN,ACTB,CSK,ARPC1A,EGFR,PIK3R1,PPP1CA,RAC1,BAIAP2,CYFIP2,GIT1APAF1,MAPK1,CAMK2B,CTSD,NFYA,CASP8,Casp10,SPHK2,ATP6V0A1,TRAF6,AKT1,CASP3,NFKB1,BCL2,CAMK2G,CREBBP,NFYC,HSPA9COX4I1,NDUFA8,ATP5A1,NDUFV2,ATP5F1,ATP6V0A1,NDUFB10,NDUFV1,ATP6V0E1,UQCRC2,ATP5C1,NDUFS1,COX6C,NDUFS3,NDUFB8,ATP5B

CACNA2D1,MAPK1,DUSP8,CACNA1E,MAX,GRB2,PPM1A,RAP1B,TRAF6,AKT1,EGFR,CASP3,NFKB1,HSPA2,RAC1,RASA1,TP53,ELK1,DUSP2,HSPA8,FLNB

USP8,CLTC,DNM1,RAB11A,DNM2,NEDD4L,AP2A2,DNM1L,CAV1,TRAF6,EGFR,HSPA2,SH3GL3,ARFGAP1,AP2B1,HSPA8,GIT1,AP2A1

CAMK2B,ATP2A2,VDAC2,CACNA1E,PTK2B,VDAC1,SPHK2,SLC25A4,EGFR,GRIN1,GRIN2A,CAMK2G,ITPR1,PDE1B,DRD1,VDAC3

APAF1,DCTN1,DLG4,DNALI1,COX4I1,NDUFA8,CLTC,ATP5A1,VDAC2,VDAC1,SIN3A,NDUFV2,ATP5F1,CASP8,NDUFB10,NDUFV1,AP2A2,TGM2,SLC25A4,CASP3,TBP,UQCRC2,ATP5C1,GRIN1,AP2B1,NDUFS1,HIP1,HDAC1,CREBBP,TP53,ITPR1,COX6C,TAF4,REST,HDAC2,HTT,NDUFS3,SP1,VDAC3,NDUFB8,ATP5B,AP2A1,TAF4BAPAF1,GSK3B,COX4I1,NDUFA8,MAPK1,ATP2A2,ATP5A1,CASP7,NDUFV2,ATP5F1,SNCA,CASP8,NDUFB10,NDUFV1,CAPN2,CASP3,UQCRC2,ATP5C1,GRIN1,APP,GRIN2A,NDUFS1,GAPDH,ITPR1,COX6C,NDUFS3,NDUFB8,ATP5B

APAF1,DCTN1,DLG4,DNALI1,COX4I1,NDUFA8,CLTC,ATP5A1,VDAC2,VDAC1,SIN3A,NDUFV2,ATP5F1,CASP8,NDUFB10,NDUFV1,AP2A2,TGM2,SLC25A4,CASP3,TBP,UQCRC2,ATP5C1,GRIN1,AP2B1,NDUFS1,HIP1,HDAC1,CREBBP,TP53,ITPR1,COX6C,TAF4,REST,HDAC2,HTT,NDUFS3,SP1,VDAC3,NDUFB8,ATP5B,AP2A1,TAF4B

Supplementary Table S7C: Enriched Cellular component with HD associated genesId Items Items_Details Support List size

13 GO:0005737 cytoplasm (CC) 263 51844 GO:0005829 cytosol (CC) 164 518

0 GO:0005634 nucleus (CC) 218 51831 GO:0005654 nucleoplasm (CC) 74 51819 GO:0005730 nucleolus (CC) 90 51869 GO:0043234 protein complex (CC) 34 51815 GO:0005886 plasma membrane (CC) 126 51814 GO:0005739 mitochondrion (CC) 67 51848 GO:0005856 cytoskeleton (CC) 50 51841 GO:0048471 perinuclear region of cytoplasm (CC) 34 518

139 GO:0015629 actin cytoskeleton (CC) 23 51884 GO:0019717 synaptosome (CC) 18 518

7 GO:0005625 soluble fraction (CC) 31 5188 GO:0005794 Golgi apparatus (CC) 47 518

175 GO:0005938 cell cortex (CC) 16 5181 GO:0005622 intracellular (CC) 71 518

49 GO:0005813 centrosome (CC) 25 51830 GO:0043005 neuron projection (CC) 13 51820 GO:0005743 mitochondrial inner membrane (CC) 23 518

273 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex 5 51810 GO:0016020 membrane (CC) 110 51873 GO:0042470 melanosome (CC) 13 518

226 GO:0030666 endocytic vesicle membrane (CC) 9 51829 GO:0017053 transcriptional repressor complex (CC) 9 518

274 GO:0043229 intracellular organelle (CC) 5 518375 GO:0008290 F-actin capping protein complex (CC) 5 518

64 GO:0045202 synapse (CC) 20 51826 GO:0030054 cell junction (CC) 26 51837 GO:0071013 catalytic step 2 spliceosome (CC) 11 518

284 GO:0046930 pore complex (CC) 5 51824 GO:0030425 dendrite (CC) 15 518

104 GO:0030426 growth cone (CC) 10 518201 GO:0000776 kinetochore (CC) 9 518134 GO:0031965 nuclear membrane (CC) 13 518

62 GO:0005681 spliceosomal complex (CC) 10 51876 GO:0070469 respiratory chain (CC) 8 518

101 GO:0030424 axon (CC) 14 51818 GO:0005624 membrane fraction (CC) 25 51874 GO:0014069 postsynaptic density (CC) 11 518

100 GO:0001726 ruffle (CC) 9 51877 GO:0005747 mitochondrial respiratory chain complex I (CC) 7 518

128 GO:0030117 membrane coat (CC) 6 51851 GO:0000139 Golgi membrane (CC) 21 518

173 GO:0005643 nuclear pore (CC) 8 518295 GO:0061202 clathrin sculpted gamma-aminobutyric acid tr 4 518

11 GO:0005783 endoplasmic reticulum (CC) 35 518

16 GO:0005789 endoplasmic reticulum membrane (CC) 26 518324 GO:0016580 Sin3 complex (CC) 4 518

97 GO:0005925 focal adhesion (CC) 10 518162 GO:0022625 cytosolic large ribosomal subunit (CC) 7 518166 GO:0030131 clathrin adaptor complex (CC) 5 518

38 GO:0043231 intracellular membrane-bounded organelle (C 15 518152 GO:0000785 chromatin (CC) 8 518228 GO:0030863 cortical cytoskeleton (CC) 5 518207 GO:0005741 mitochondrial outer membrane (CC) 9 518

98 GO:0045121 membrane raft (CC) 10 51859 GO:0000502 proteasome complex (CC) 7 518

350 GO:0060203 clathrin sculpted glutamate transport vesicl 3 518412 GO:0070083 clathrin sculpted monoamine transport vesic 3 518242 GO:0030665 clathrin coated vesicle membrane (CC) 4 518187 GO:0001725 stress fiber (CC) 6 518158 GO:0016605 PML body (CC) 7 518233 GO:0005905 coated pit (CC) 6 518383 GO:0030660 Golgi-associated vesicle membrane (CC) 3 518142 GO:0005840 ribosome (CC) 11 518113 GO:0005753 mitochondrial proton-transporting ATP syntha 4 518148 GO:0043197 dendritic spine (CC) 7 518

53 GO:0005792 microsome (CC) 14 518293 GO:0005832 chaperonin-containing T-complex (CC) 3 518

58 GO:0043025 neuronal cell body (CC) 12 51821 GO:0005667 transcription factor complex (CC) 12 518

159 GO:0005901 caveola (CC) 6 518231 GO:0042645 mitochondrial nucleoid (CC) 5 518318 GO:0042641 actomyosin (CC) 3 518367 GO:0017146 N-methyl-D-aspartate selective glutamate rec 3 518319 GO:0005669 transcription factor TFIID complex (CC) 4 518

80 GO:0005635 nuclear envelope (CC) 8 518308 GO:0035517 PR-DUB complex (CC) 2 518410 GO:0045261 proton-transporting ATP synthase complex, cata 2 518210 GO:0031252 cell leading edge (CC) 4 518268 GO:0030122 AP-2 adaptor complex (CC) 3 518176 GO:0005819 spindle (CC) 8 518

56 GO:0005768 endosome (CC) 13 518211 GO:0033267 axon part (CC) 3 518330 GO:0035098 ESC/E(Z) complex (CC) 3 518

57 GO:0031410 cytoplasmic vesicle (CC) 13 518325 GO:0005626 insoluble fraction (CC) 5 518344 GO:0005916 fascia adherens (CC) 3 518

93 GO:0005911 cell-cell junction (CC) 7 51846 GO:0000790 nuclear chromatin (CC) 6 51866 GO:0030672 synaptic vesicle membrane (CC) 5 518

272 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complex 2 518380 GO:0071942 XPC complex (CC) 2 518386 GO:0060201 clathrin sculpted acetylcholine transport ves 2 518

390 GO:0005924 cell-substrate adherens junction (CC) 2 518157 GO:0042734 presynaptic membrane (CC) 5 518

65 GO:0008021 synaptic vesicle (CC) 6 518194 GO:0005802 trans-Golgi network (CC) 6 518253 GO:0016459 myosin complex (CC) 5 518165 GO:0030027 lamellipodium (CC) 7 518322 GO:0000118 histone deacetylase complex (CC) 4 518

36 GO:0030529 ribonucleoprotein complex (CC) 8 518103 GO:0043198 dendritic shaft (CC) 4 518297 GO:0016602 CCAAT-binding factor complex (CC) 2 518355 GO:0005954 calcium- and calmodulin-dependent protein k 2 518277 GO:0016581 NuRD complex (CC) 3 518244 GO:0005605 basal lamina (CC) 3 518

43 GO:0005764 lysosome (CC) 9 518122 GO:0044297 cell body (CC) 3 518156 GO:0045177 apical part of cell (CC) 5 518

33 GO:0009986 cell surface (CC) 12 518336 GO:0030118 clathrin coat (CC) 2 518345 GO:0000275 mitochondrial proton-transporting ATP synthas 2 518392 GO:0044431 Golgi apparatus part (CC) 2 518401 GO:0045334 clathrin-coated endocytic vesicle (CC) 2 518

67 GO:0005874 microtubule (CC) 11 518116 GO:0005769 early endosome (CC) 7 518

94 GO:0005912 adherens junction (CC) 4 518237 GO:0030136 clathrin-coated vesicle (CC) 4 518195 GO:0005770 late endosome (CC) 5 518199 GO:0005871 kinesin complex (CC) 3 518108 GO:0042995 cell projection (CC) 8 518150 GO:0043195 terminal button (CC) 4 518

35 GO:0016324 apical plasma membrane (CC) 9 518259 GO:0005682 U5 snRNP (CC) 2 518301 GO:0070062 extracellular vesicular exosome (CC) 2 518393 GO:0000125 PCAF complex (CC) 2 518

25 GO:0016323 basolateral plasma membrane (CC) 7 51817 GO:0015630 microtubule cytoskeleton (CC) 6 51845 GO:0005758 mitochondrial intermembrane space (CC) 4 518

280 GO:0031941 filamentous actin (CC) 3 51878 GO:0005759 mitochondrial matrix (CC) 9 518

346 GO:0033017 sarcoplasmic reticulum membrane (CC) 3 518221 GO:0034747 Axin-APC-beta-catenin-GSK3B complex (CC) 2 518267 GO:0030130 clathrin coat of trans-Golgi network vesicle (C 2 518298 GO:0042587 glycogen granule (CC) 2 518342 GO:0005890 sodium:potassium-exchanging ATPase complex 2 518370 GO:0016461 unconventional myosin complex (CC) 2 518

2 GO:0016607 nuclear speck (CC) 7 518316 GO:0005891 voltage-gated calcium channel complex (CC) 3 518179 GO:0005689 U12-type spliceosomal complex (CC) 3 518

87 GO:0000922 spindle pole (CC) 5 518

119 GO:0031461 cullin-RING ubiquitin ligase complex (CC) 2 518200 GO:0005915 zonula adherens (CC) 2 518215 GO:0070688 MLL5-L complex (CC) 2 518296 GO:0044306 neuron projection terminus (CC) 2 518323 GO:0044428 nuclear part (CC) 2 518358 GO:0031095 platelet dense tubular network membrane (CC 2 518220 GO:0016328 lateral plasma membrane (CC) 3 518

96 GO:0032587 ruffle membrane (CC) 4 518198 GO:0010008 endosome membrane (CC) 7 518212 GO:0016529 sarcoplasmic reticulum (CC) 3 518266 GO:0016604 nuclear body (CC) 3 518

54 GO:0030127 COPII vesicle coat (CC) 2 518225 GO:0035253 ciliary rootlet (CC) 2 518338 GO:0048786 presynaptic active zone (CC) 2 518

89 GO:0005694 chromosome (CC) 10 518141 GO:0071339 MLL1 complex (CC) 3 518

72 GO:0030659 cytoplasmic vesicle membrane (CC) 5 518302 GO:0031080 Nup107-160 complex (CC) 2 518368 GO:0032993 protein-DNA complex (CC) 2 518188 GO:0008180 signalosome (CC) 3 518

86 GO:0005815 microtubule organizing center (CC) 5 51847 GO:0005876 spindle microtubule (CC) 3 51861 GO:0005795 Golgi stack (CC) 3 518

121 GO:0031234 extrinsic to internal side of plasma membrane 3 518143 GO:0005868 cytoplasmic dynein complex (CC) 2 518177 GO:0035631 CD40 receptor complex (CC) 2 518239 GO:0071564 npBAF complex (CC) 2 518256 GO:0005719 nuclear euchromatin (CC) 2 518397 GO:0071203 WASH complex (CC) 2 518153 GO:0005765 lysosomal membrane (CC) 6 518183 GO:0019861 flagellum (CC) 3 518

55 GO:0012507 ER to Golgi transport vesicle membrane (CC) 3 518181 GO:0005923 tight junction (CC) 5 518202 GO:0000777 condensed chromosome kinetochore (CC) 4 518

85 GO:0030288 outer membrane-bounded periplasmic space ( 2 518135 GO:0008287 protein serine/threonine phosphatase comple 2 518227 GO:0031143 pseudopodium (CC) 2 518241 GO:0071565 nBAF complex (CC) 2 518279 GO:0032839 dendrite cytoplasm (CC) 2 518287 GO:0051233 spindle midzone (CC) 2 518136 GO:0030692 Noc4p-Nop14p complex (CC) 1 518351 GO:0031074 nucleocytoplasmic shuttling complex (CC) 1 518406 GO:0044446 intracellular organelle part (CC) 1 518411 GO:0005943 1-phosphatidylinositol-4-phosphate 3-kinase, 1 518414 GO:0005854 nascent polypeptide-associated complex (CC) 1 518419 GO:0070438 mTOR-FKBP12-rapamycin complex (CC) 1 518420 GO:0042585 germinal vesicle (CC) 1 518421 GO:0005754 mitochondrial proton-transporting ATP synthase 1 518

422 GO:0000235 astral microtubule (CC) 1 51828 GO:0045211 postsynaptic membrane (CC) 7 518

112 GO:0000795 synaptonemal complex (CC) 2 518269 GO:0005942 phosphatidylinositol 3-kinase complex (CC) 2 518120 GO:0005834 heterotrimeric G-protein complex (CC) 3 518178 GO:0009898 internal side of plasma membrane (CC) 3 518

79 GO:0031966 mitochondrial membrane (CC) 4 518133 GO:0035267 NuA4 histone acetyltransferase complex (CC) 2 518205 GO:0033276 transcription factor TFTC complex (CC) 2 518230 GO:0000242 pericentriolar material (CC) 2 518321 GO:0031528 microvillus membrane (CC) 2 518

91 GO:0032154 cleavage furrow (CC) 3 51839 GO:0005720 nuclear heterochromatin (CC) 2 518

125 GO:0031674 I band (CC) 2 518190 GO:0043209 myelin sheath (CC) 2 518240 GO:0016514 SWI/SNF complex (CC) 2 518305 GO:0016585 chromatin remodeling complex (CC) 2 518

92 GO:0031594 neuromuscular junction (CC) 3 51834 GO:0016023 cytoplasmic membrane-bounded vesicle (CC) 5 518

196 GO:0030667 secretory granule membrane (CC) 2 518

Reference Reference Hyp Hyp_c Genes5302 34208 1.92E-79 8.14E-77 PAFAH1B1,FLNB,PARK2,SGK1,TFEB,GRB2,SP1,UBR4,HIP1,GPI,VPRBP,SEC24C,XRCC6,CASP2,UBE2K,SREBF2,NFKB1,NSF,DYNC1H1,SIRT1,MYO9B,EDC4,TNFRSF8,SYMPK,CASP6,PSMC2,FEZ1,MAPK1,PPP1CA,MED15,TUBB,ANXA6,BTG1,MARCKS,NEDD4L,TJP2,FMNL3,SSRP1,GFAP,EPB41L1,API5,DDX24,PAX6,EZR,DPYSL2,CCT4,ILK,CCT2,MAP3K10,DNM2,YWHAE,MYH10,GPHN,MLF1,ADD1,HDAC3,MTOR,TRIO,CTBP1,BCL2,EGR1,SYT1,KIF5C,TRAF6,BAIAP2,SPG20,YWHAH,RPL23,ARF4,TNIP1,ADAR,RPL14,G3BP2,FLII,PACSIN1,NGFR,HDLBP,CABIN1,CSK,CAPZA1,BAG1,DDB1,CAV1,CABLES1,PFKM,AP3D1,PTK2B,HMGB2,DIAPH1,DNAJB1,PRKRA,SNX27,APP,ARFGAP1,WDR6,LDHA,NACA,PTK6,FABP5,MAGED1,TGM2,STIP1,ZDHHC17,SRRT,MYO6,TPM2,YWHAZ,VPS39,MLLT4,TP53,DBN1,RASA1,EEF1A1,TAF4,USP14,PRKAA2,RAB3A,AASDHPPT,PIK3R1,RAP1B,CAPN2,CEP63,DYNC1I2,PPL,ARPC1A,GMDS,ADD3,HSPA8,PSMD8,DNM1L,TEKT1,USP21,CEP250,RBM19,TBCD,TCP1,AP1G1,HDAC2,CTH,FNBP1,BCAS4,MLF2,FNTA,ITPR1,NR3C1,SMG5,PPFIA3,STXBP1,CTNNB1,TYK2,MCM3AP,AKT1,GIT1,ATP6V0A1,TRIP10,TAF4B,CAPZB,HSPA4,HDAC1,PDE1B,HUWE1,CAMK2B,DNM1,HSPA9,HADHA,NUMA1,PPP1R13B,SEPT7,HTT,CAMK1D,DCTN1,GJA1,REST,SNCA,CDH13,ZFP36L2,UBQLN2,TUBG1,INPPL1,MAD1L1,TPR,APAF1,SUMO1,TRAF1,ADD2,UBQLN1,RAD51C,SORBS1,USP9X,CHD3,DLD,PSMA1,SIN3B,TSC2,FHOD3,XPC,EGFR,RAD23B,DUSP8,CBS,SPHK2,PGM1,TRAF3,NISCH,ARHGAP1,MAX,ACTB,CAPZA2,CYFIP2,USP7,NDRG2,YWHAB,CRNKL1,ACTR1B,GOT1,DLG4,TBP,CASP1,GSK3B,ARHGEF6,LANCL1,INPP5B,EFTUD2,PFN2,NUP62,BECN1,ACTN1,GCN1L1,GNAI2,CASP7,EWSR1,YBX1,PSPC1,RECQL5,CASK,SH3GL3,USP8,TMOD2,GSN,UCHL3,NCOR1,NXT2,UPF1,GSTP1,BAP1,VPS35,SQSTM1,TLN1,YWHAG,NUP153,SNAP25,CREBBP,ATM,WHSC1,ARL2,UGP2,CASP3,OGT,CASP8,RPS6,GAPDH,CORO1B,HMGB12146 34208 9.82E-71 2.08E-68 PAFAH1B1,PARK2,GRB2,GPI,SEC24C,CASP2,PPP2R2A,NFKB1,AP2A2,NAPA,NSF,DYNC1H1,SRGAP1,MYO9B,EDC4,CASP6,PSMC2,MAPK1,EIF2AK2,PPP1CA,TUBB,Ube3a,EPB41L1,SRGAP2,EZR,DPYSL2,CCT4,ILK,CCT2,RPL7,DNM2,YWHAE,ADD1,MTOR,TRIO,BCL2,TRAF6,BAIAP2,USP19,ARHGAP18,RPL23,RPL15,RPL14,RPL13,G3BP2,NGFR,CSK,CAPZA1,BAG1,CAV1,CABLES1,PFKM,PTK2B,SNX27,APP,ARFGAP1,LDHA,PAICS,MYO6,TPM2,YWHAZ,MLLT4,TP53,RASA1,EEF1A1,RANBP2,CAMK2G,PRKAA2,AASDHPPT,PIK3R1,RAP1B,CEP63,DYNC1I2,HSPA8,PSMD8,DNM1L,CEP250,NUP98,AP1B1,TCP1,ALDOA,AP1G1,FNTA,NR3C1,SMG5,STXBP1,CTNNB1,TYK2,MCM3AP,AKT1,THY1,TRIP10,CAPZB,HSPA4,HDAC1,PDE1B,CAMK2B,NUMA1,HTT,RAB14,DCTN1,PPM1A,REST,SNCA,TUBG1,FABP3,PAH,CLTC,INPPL1,MAD1L1,APAF1,ANAPC1,SORBS1,NUP160,PSMA1,TSC2,CBS,SPHK2,PGM1,TRAF3,NISCH,ARHGAP1,CUL1,BUB3,ACTB,CAPZA2,NDRG2,YWHAB,ASNS,GOT1,MYL6,CASP1,GSK3B,AP2B1,RAC1,SEC23A,ARHGEF6,RAPGEF1,INPP5B,ACTN1,RPL6,GNAI2,CASP7,MAT2A,USP8,GSN,ARHGEF7,RPLP2,UPF1,GSTP1,VPS35,SQSTM1,TLN1,YWHAG,AP2A1,ARL2,UGP2,GSS,CASP3,OGT,CASP8,RPS6,GAPDH,PSMD35441 34208 1.83E-46 2.58E-44 PAFAH1B1,MECP2,FLNB,PARK2,ELK1,SGK1,TFEB,GRB2,SP1,UBR4,HIP1,GPI,VPRBP,SEC24C,XRCC6,ZNF292,CASP2,SREBF2,SF3A3,NFKB1,SFMBT2,SIRT1,EDC4,SYMPK,CASP6,PSMC2,MAPK1,PPP1CA,NCOR2,SRRM2,MED15,Ube3a,BTG1,TJP2,SSRP1,API5,PAX6,BCL11B,SIN3A,CCT4,COX4I1,CCT2,NFYA,GTF3C5,DNM2,MLF1,ADD1,HDAC3,MTOR,CTBP1,BCL2,EGR1,TRAF6,BAIAP2,ZNF207,DUSP2,ASXL1,TNIP1,ADAR,TRRAP,BATF,FLII,PRPF8,SNRNP200,NGFR,HDLBP,CABIN1,BAG1,DDB1,CABLES1,RNGTT,PTK2B,HMGB2,DOT1L,CHD8,DNAJB1,DRD1,POU2AF1,SF3B3,KIAA0556,NACA,PTK6,STIP1,SRRT,MYO6,YWHAZ,MLLT4,SMARCA4,MAF,SRCAP,TP53,CREBL2,EEF1A1,RANBP2,MEF2D,TAF4,PRKAA2,PIK3R1,RBM5,EP400,DNAJC1,CAPN2,PPL,POLR3E,PSMD8,USP21,RBM19,NUP98,DDX5,TCP1,HDAC2,EZH1,FADS1,CTH,MLF2,NR3C1,SMG5,SUPT5H,CTNNB1,TYK2,MCM3AP,AKT1,ATP6V0A1,TAF4B,HSPA4,MED23,HDAC1,PDE1B,HUWE1,POU3F2,SBF1,NUMA1,PPP1R13B,SEPT7,SNW1,KAT2B,HTT,CAMK1D,PPM1A,REST,SNCA,ZFP36L2,UBQLN2,MAD1L1,TPR,APAF1,SUMO1,SF3B2,CPT2,UBQLN1,RAD51C,ANAPC1,SORBS1,CHD3,NUP160,PSMA1,SIN3B,PPIL2,TSC2,FHOD3,XPC,EGFR,RAD23B,USP1,DUSP8,CBS,MAX,BUB3,USP7,NDRG2,YWHAB,CRNKL1,MYCBP2,MYEF2,BMP2K,CBFA2T2,TP53INP1,GSK3B,ARNTL,LANCL1,EFTUD2,ZNF91,NUP62,ACTN1,GNAI2,EWSR1,YBX1,PSPC1,RECQL5,CASK,ZNF24,USP8,SUGP2,UCHL3,NCOR1,ZMYND8,DHX8,NXT2,GSTP1,BAP1,SQSTM1,NFYC,NUP153,CREBBP,ATM,WHSC1,ARL2,SMARCC2,CASP3,OGT,CASP8,RPS6,RNMT,GAPDH,NOP14,PPP1R16B,HIST1H2AC,HMGB1

891 34208 5.93E-33 6.27E-31 XRCC6,SF3A3,NFKB1,SIRT1,SYMPK,CASP6,PSMC2,MAPK1,PPP1CA,NCOR2,MED15,SSRP1,SIN3A,GTF3C5,HDAC3,EGR1,DUSP2,ADAR,PRPF8,SNRNP200,NGFR,DDB1,RNGTT,HMGB2,SF3B3,SRRT,MYO6,YWHAZ,TP53,CAMK2G,TAF4,PRKAA2,RBM5,POLR3E,PSMD8,RBM19,NUP98,HDAC2,NR3C1,SUPT5H,AKT1,TAF4B,MED23,HDAC1,CAMK2B,NUMA1,SNW1,KAT2B,TPR,SUMO1,SF3B2,RAD51C,ANAPC1,PSMA1,SIN3B,XPC,RAD23B,USP1,CUL1,TBP,EFTUD2,CASP7,YBX1,PSPC1,RECQL5,NCOR1,SQSTM1,NUP153,CREBBP,ATM,CASP3,RNMT,PSMD3,HMGB11461 34208 3.58E-30 3.03E-28 PAFAH1B1,SP1,GPI,SEC24C,SF3A3,NFKB1,SIRT1,SYMPK,PSMC2,PPP1CA,NCOR2,SRRM2,API5,DDX24,PAX6,EZR,SIN3A,CCT4,CCT2,CTBP1,TRAF6,BAIAP2,RPL23,ZNF207,ADAR,TRRAP,FLII,SNRNP200,CABIN1,PTK2B,HMGB2,DNAJB1,KIAA0556,PTK6,MLLT4,TP53,MEF2D,TAF4,RBM5,POLR3E,PSMD8,RBM19,DDX5,TCP1,EZH1,ITPR1,NR3C1,SUPT5H,ATP6V0A1,TAF4B,HSPA4,HDAC1,PDE1B,HUWE1,HADHA,NUMA1,PPP1R13B,SEPT7,SNW1,HTT,REST,APAF1,SF3B2,CPT2,SORBS1,PSMA1,PPIL2,FHOD3,RAD23B,CBS,MAX,BUB3,NDRG2,YWHAB,MYEF2,BMP2K,GSK3B,EFTUD2,PSPC1,RECQL5,BAP1,NUP153,WHSC1,SMARCC2,CASP3,OGT,RPS6,RNMT,NOP14,HMGB1

217 34208 2.16E-24 1.52E-22 PARK2,GRB2,NFKB1,MAPK1,ANXA6,SYP,DPYSL2,ATP2A2,ILK,CAV1,HMGB2,CHD8,WDR6,MAGED1,STIP1,YWHAZ,SRCAP,TP53,RAB3A,CEP250,RAB11A,ITPR1,NR3C1,STXBP1,HTT,UBQLN1,TSC2,ACTB,STX1A,BECN1,GSN,GSTP1,NUP153,CASP83575 34208 7.52E-20 4.55E-18 FLNB,SGK1,GPI,AP2A2,SLC41A1,NSF,MICA,TNFRSF8,SYMPK,ATP5B,FEZ1,GRIN2A,MARCKS,RASD2,TJP2,EPB41L1,EZR,VAMP2,ILK,GNAZ,DNM2,MYH10,NCKAP1,GPHN,ZFYVE27,MBP,ADD1,SYT1,TRAF6,BAIAP2,ARF4,TNFSF13B,NGFR,HDLBP,RAB10,CNR1,CSK,CAV1,CACNA1E,PTK2B,DIAPH1,APP,DRD1,KIAA0556,PTK6,NEGR1,MAGED1,SLC2A3,TGM2,MYO6,MLLT4,RAB28,RASA1,CAMK2G,VAPA,USP14,RAB3A,PIK3R1,RAP1B,CAPN2,PPL,GRIN1,ADD3,HSPA8,TBCD,RAB11A,AGPAT3,TCP1,FNBP1,ITPR1,ADORA2A,STXBP1,CTNNB1,AKT1,ENTPD3,THY1,ATP6V0A1,TRIP10,SLC16A1,GNB1,CAMK2B,PPP1R13B,SEPT7,RAB14,GJA1,SNCA,CDH13,UBQLN2,CNTN1,CLTC,INPPL1,CLDN12,ADD2,SORBS1,TMPRSS5,EGFR,KCNN3,ABCC10,NISCH,ARHGAP1,ATP1A1,DLG4,SNAP91,GSK3B,AP2B1,RAC1,CD22,STX1A,ATP5A1,ACTN1,ATP1B1,GNAI2,EWSR1,CASK,USP8,WNT10A,GSTP1,TLN1,KCNC1,VDAC1,SNAP25,AP2A1,ENTPD1,CASP3,OGT,PPP1R16B1394 34208 7.69E-17 4.07E-15 PARK2,NDUFV1,SGK1,CASP2,NFKB1,SLC25A3,PSMC2,ATP5B,FEZ1,MAPK1,SLC25A4,DPYSL2,COX4I1,UQCRC2,YWHAE,MTOR,BCL2,SPG7,MRPS5,NDUFV2,BAG1,CAV1,LDHA,TGM2,YWHAZ,TRAP1,TOMM22,TP53,COX6C,PPL,RAB11A,ECH1,ATP5C1,STXBP1,ATP5F1,SUCLA2,SLC16A1,HSPA9,HADHA,NDUFS3,SLC25A11,VDAC3,CPT1B,CLTC,MAD1L1,CPT2,RAD51C,CHCHD4,DLD,SLC25A12,TRAF3,VDAC2,ATP5A1,GLOD4,NDUFS1,NDUFB10,UCHL3,NDUFA8,VDAC1,NDUFB8,SLC25A13,ARL2,ME2,CASP3,CASP8,NOP14,HSPA2

846 34208 3.09E-16 1.45E-14 PAFAH1B1,UBR4,HIP1,DYNC1H1,SYMPK,MAPK1,TUBB,EPB41L1,EZR,CCT4,DNM2,GPHN,ADD1,KIF5C,FLII,CAPZA1,PTK2B,DIAPH1,TPM2,CEP63,DYNC1I2,PPL,ARPC1A,ADD3,TEKT1,CEP250,TCP1,FNBP1,CTNNB1,TYK2,TRIP10,CAPZB,CAMK2B,DNM1,DCTN1,SNCA,TUBG1,INPPL1,ADD2,SORBS1,CHD3,FHOD3,ACTB,ACTR1B,NUP62,ACTN1,GNAI2,TMOD2,ARL2,PCLO417 34208 2.27E-15 9.60E-14 PAFAH1B1,PARK2,SEC24C,MYO9B,ANXA6,VAMP2,TRAF6,BAG1,CAV1,PTK2B,HMGB2,PRKRA,APP,GALNT2,MYO6,YWHAZ,VAPA,CEP250,CTNNB1,TRIP10,RAB14,UBQLN1,RAD51C,TSC2,EGFR,CYFIP2,NDRG2,YWHAB,SEC23A,GSN,NCOR1,SNAP25,RPS6,GAPDH180 34208 6.32E-15 2.43E-13 FLNB,MYO9B,MARCKS,EZR,BAIAP2,CAPZA1,DBN1,ARPC1A,ALDOA,CORO1C,CAPZB,SEPT7,SNCA,MAD1L1,PGM1,ACTB,CAPZA2,PFN2,CASK,GSN,TLN1,SNAP25,CORO1B111 34208 8.50E-14 2.77E-12 GPI,GRIN2A,SYP,VAMP2,DPYSL2,APP,USP14,RAB3A,PIK3R1,GRIN1,NR3C1,SEPT7,SNCA,EPS8,CYFIP2,DLG4,STX1A,SNAP25390 34208 7.91E-14 2.79E-12 PAFAH1B1,GPI,SYN1,CASP2,MAPK1,DPYSL2,MTOR,TNFSF13B,CAV1,PFKM,DNAJB1,WDR6,YWHAZ,USP14,RAB3A,PIK3R1,CAPN2,ADD3,DNAJA2,AKT1,CBS,ACTB,ASNS,GOT1,PPP1R3D,FBLN1,CASP7,SNAP25,UGP2,GSS,HMGB1958 34208 2.14E-12 6.47E-11 SEC16A,PARK2,GRB2,HIP1,SYN1,SEC24C,SREBF2,DYNC1H1,MAPK1,MED15,COG1,MTOR,ARF4,RAB10,CSK,CAV1,AP3D1,APP,ARFGAP1,ENTPD6,STIP1,ZDHHC17,GALNT2,MYO6,B4GALT6,SRCAP,DNM1L,AP1B1,TCP1,AP1G1,ATP6V0A1,TRIP10,CALU,HTT,RAB14,GJA1,INPPL1,APAF1,TSC2,EGFR,GCNT1,NDRG2,MYEF2,SEC23A,BECN1,MGAT1,ARL2106 34208 6.41E-12 1.81E-10 PAFAH1B1,FLNB,MYO9B,MARCKS,EZR,MYH10,TRAF6,CAV1,PTK2B,MYO6,ADD3,FNBP1,CTNNB1,TRIP10,SEPT7,SNCA

1962 34208 9.90E-12 2.62E-10 SP1,ZNF292,CASP2,SF3A3,SRGAP1,EIF2AK2,Ube3a,NEDD4L,TBC1D5,SRGAP2,BCL11B,EZR,RPL7,TRIO,BCL2,DNAJC21,EGR1,ARHGAP18,TBC1D22A,RPL15,ZNF207,ARF4,TNIP1,ADAR,RPL14,RPL13,G3BP2,MRPS5,CAV1,PRKRA,GSPT1,DBN1,RASA1,PIK3R1,RBM5,RAP1B,CAPN2,GMDS,HSPA8,NR3C1,HUWE1,RAB14,REST,GGA3,APAF1,GBF1,TSC2,EGFR,ARHGAP1,CRNKL1,CASP1,ARHGEF6,RAPGEF1,INPP5B,ZNF91,RPL6,EWSR1,ZNF24,USP8,SUGP2,ARHGEF7,RPLP2,UCHL3,NXT2,GSTP1,BAP1,NFYC,NUP153,ARL2,SMARCC2,RPS6323 34208 3.72E-11 9.25E-10 PAFAH1B1,DYNC1H1,FEZ1,MARCKS,ODF2L,FLII,CSK,CEP63,DYNC1I2,CEP250,CTNNB1,DCTN1,TUBG1,MAD1L1,SORBS1,CHD3,PSMA1,NDRG2,YWHAB,ACTR1B,GSK3B,GNAI2,TLN1,ARL2,OGT

81 34208 2.79E-10 6.55E-09 PARK2,PPP1CA,GRIN2A,SYT1,KIF5C,DIAPH1,CTNNB1,PPM1A,CDH13,STX1A,SNAP25,CASP8,HMGB1308 34208 4.58E-10 1.02E-08 NDUFV1,SLC25A3,SLC25A4,COX4I1,UQCRC2,NDUFV2,TOMM22,COX6C,ATP5C1,ATP5F1,HADHA,NDUFS3,SLC25A11,CPT2,SLC25A12,VDAC2,ATP5A1,NDUFS1,NDUFB10,NDUFA8,VDAC1,NDUFB8,SLC25A13

5 34208 7.81E-10 1.65E-08 NAPA,VAMP2,NAPB,STX1A,SNAP254065 34208 8.44E-10 1.70E-08 SEC16A,PAFAH1B1,NDUFV1,GRB2,UBR4,HIP1,SEC24C,SREBF2,AP2A2,NAPA,MICA,SLC25A3,SLC25A4,DNAJA1,SLC35F5,SYP,COG1,ATP2A2,COX4I1,UQCRC2,ADD1,MTOR,BCL2,SPG7,SYT1,USP19,NDUFV2,SNX25,AP3D1,CACNA1E,CYP2C8,ENTPD6,SORCS1,SLC2A3,ZDHHC17,GALNT2,VPS39,NAPB,TOMM22,B4GALT6,COX6C,DNAJC1,RAP1B,ADD3,DNM1L,ENTPD2,NUP98,AP1B1,KCNRG,DNAJA2,ATP5C1,AP1G1,FADS1,ITPR1,NR3C1,ATP5F1,CTNNB1,TYK2,ASPH,GPM6A,CAPZB,NDUFS3,SLC25A11,CDH13,VDAC3,CPT1B,GGA3,KIAA0922,TPR,SUMO1,CPT2,ADD2,TMPRSS5,TSC2,EGFR,SLC25A12,HMGCR,SPHK2,PIGM,GCNT1,CAPZA2,ATP1A1,CACNA2D1,AP2B1,RAC1,SEC23A,CD22,LANCL1,SEC61A2,INPP5B,STX1A,ATP6V0E1,VDAC2,BECN1,ATP1B1,NDUFS1,SGPP2,BCAN,SH3GL3,SLC15A4,POMT2,MGAT1,NDUFB10,CTNS,VPS35,VDAC1,NDUFB8,SLC25A13,PCLO,GAPDH

89 34208 9.35E-10 1.80E-08 ANXA6,CCT4,CTSD,YWHAE,YWHAZ,HSPA8,PPIB,ATP6V0A1,CALU,CLTC,ATP1A1,YWHAB,RAC133 34208 1.09E-09 2.01E-08 AP2A2,VAMP2,SYT1,CAV1,CAMK2G,CAMK2B,DLG4,AP2B1,AP2A140 34208 7.04E-09 1.24E-07 NCOR2,SIN3A,HDAC3,CTBP1,REST,YWHAB,NCOR1,SMARCC2,HMGB1

7 34208 1.60E-08 2.60E-07 SYN1,SYP,SYT1,RAB3A,SNAP257 34208 1.60E-08 2.60E-07 ADD1,CAPZA1,CAPZB,ADD2,CAPZA2

288 34208 2.14E-08 3.35E-07 SYN1,GRIN2A,SYP,VAMP2,DNM2,GPHN,ADD1,SYT1,APP,GRIN1,CTNNB1,SNCA,SUMO1,CYFIP2,DLG4,STX1A,BCAN,SNAP25,PCLO,RIMS4475 34208 2.36E-08 3.57E-07 SYN1,SYMPK,GRIN2A,TJP2,SYP,VAMP2,DNM2,GPHN,SYT1,BAIAP2,MLLT4,PPL,GRIN1,TBCD,TCP1,CTNNB1,GJA1,SNCA,CLDN12,SORBS1,CYFIP2,DLG4,STX1A,SNAP25,PCLO,RIMS4

79 34208 3.09E-08 4.50E-07 SF3A3,SRRM2,PRPF8,SNRNP200,SF3B3,DDX5,SNW1,SF3B2,CRNKL1,EFTUD2,DHX89 34208 9.36E-08 1.32E-06 BCL2,VDAC3,NUP62,VDAC2,VDAC1

182 34208 1.37E-07 1.71E-06 SREBF2,FEZ1,DPYSL2,ZFYVE27,MTOR,NEGR1,DBN1,GRIN1,ADORA2A,THY1,HTT,SUMO1,TSC2,MAX,BCAN72 34208 1.35E-07 1.72E-06 PAFAH1B1,DPYSL2,MYH10,PTK2B,THY1,SNCA,TSC2,NDRG2,TMOD2,SNAP2555 34208 1.34E-07 1.77E-06 PAFAH1B1,SIN3A,NUP98,KAT2B,DCTN1,MAD1L1,TPR,NUP160,BUB3

133 34208 1.30E-07 1.77E-06 PAFAH1B1,BCL2,TRAF6,MYO6,DNAJC1,NUP98,TPR,SUMO1,EGFR,NUP62,RECQL5,NUP153,WHSC175 34208 2.00E-07 2.41E-06 SF3A3,API5,SNRNP200,SF3B3,RBM5,SNW1,SF3B2,CRNKL1,EFTUD2,DHX843 34208 2.38E-07 2.80E-06 NDUFV1,UQCRC2,NDUFV2,NDUFS3,NDUFS1,NDUFB10,NDUFA8,NDUFB8

173 34208 4.48E-07 5.12E-06 FEZ1,DPYSL2,ILK,MYH10,ZFYVE27,PTK2B,APP,DRD1,ADORA2A,HTT,SNCA,ACTB,MYCBP2,SNAP25523 34208 5.62E-07 6.25E-06 HIP1,XRCC6,CASP2,GFAP,ATP2A2,BCL2,DRD1,ENTPD6,FADS1,ADORA2A,CTNNB1,AKT1,SLC16A1,HTT,RAB14,PPM1A,GJA1,CNTN1,TSC2,SPHK2,NISCH,ATP1A1,ATP6V0E1,GNAI2,BCAN107 34208 7.23E-07 7.84E-06 GRIN2A,DNM2,PTK2B,YWHAZ,GRIN1,ITPR1,NR3C1,ADORA2A,EPS8,DLG4,SNAP91

72 34208 1.43E-06 1.51E-05 EZR,BAIAP2,PTK6,MYO6,RASA1,ARHGAP1,ACTN1,GSN,TLN139 34208 1.77E-06 1.83E-05 NDUFV1,NDUFV2,NDUFS3,NDUFS1,NDUFB10,NDUFA8,NDUFB826 34208 2.08E-06 2.10E-05 AP2A2,AP3D1,AP1B1,AP1G1,AP2B1,AP2A1

420 34208 2.24E-06 2.20E-05 SEC16A,SEC24C,SREBF2,COG1,DNM2,MTOR,CAV1,AP3D1,ENTPD6,ZDHHC17,B4GALT6,AP1B1,AP1G1,ADORA2A,RAB14,GJA1,GBF1,EGFR,GCNT1,SEC23A,MGAT158 34208 2.58E-06 2.48E-05 RANBP2,NUP98,MAD1L1,TPR,SUMO1,NUP160,NUP62,NUP153

8 34208 3.47E-06 3.26E-05 VAMP2,SYT1,RAB3A,HSPA81000 34208 4.90E-06 4.51E-05 SEC16A,PARK2,SGK1,SEC24C,SREBF2,GNAZ,ZFYVE27,MTOR,BCL2,USP19,CAV1,CYP2C8,DRD1,TP53,VAPA,DNAJC1,AGPAT3,KCNRG,PPIB,FADS1,ITPR1,ASPH,THY1,CALU,HTT,GJA1,UBQLN1,EGFR,HMGCR,PIGM,SEC23A,SEC61A2,SGPP2,POMT2,NDUFB8

642 34208 6.94E-06 6.25E-05 SEC16A,SGK1,SEC24C,SREBF2,ATP2A2,ZFYVE27,MTOR,BCL2,USP19,CYP2C8,DRD1,VAPA,DNAJC1,AGPAT3,FADS1,ITPR1,ASPH,GJA1,EGFR,HMGCR,PIGM,SEC23A,SEC61A2,CASP7,SGPP2,POMT210 34208 1.02E-05 8.95E-05 SIN3A,HDAC2,HDAC1,NCOR1

116 34208 1.13E-05 9.76E-05 FLNB,MAPK1,EZR,ILK,CAV1,PTK2B,GIT1,SORBS1,ACTN1,TLN152 34208 1.30E-05 0.0001079 RPL7,RPL23,RPL15,RPL14,RPL13,RPL6,RPLP221 34208 1.30E-05 0.00011 AP2A2,AP1B1,AP1G1,GGA3,AP2B1

269 34208 1.77E-05 0.0001439 HIP1,SEC24C,CSK,APP,ZDHHC17,MEF2D,ATP6V0A1,CBS,ARHGAP1,LANCL1,NUP62,YBX1,BAP1,TLN1,ME275 34208 1.82E-05 0.000145 SIN3A,HDAC3,MAF,TP53,CAPN2,SNW1,REST,UPF123 34208 2.10E-05 0.0001643 EZR,CAPZB,ACTB,CAPZA2,DLG4

102 34208 2.57E-05 0.0001978 SLC25A4,MTOR,BCL2,DNM1L,GJA1,VDAC3,CPT1B,VDAC2,VDAC1128 34208 2.68E-05 0.0002022 CAV1,PTK2B,ITPR1,THY1,GJA1,SORBS1,EGFR,GNAI2,SNAP25,CASP8

60 34208 3.38E-05 0.0002386 PSMC2,USP14,PSMD8,UBQLN1,PSMA1,RAD23B,PSMD35 34208 3.37E-05 0.000242 VAMP2,SYT1,RAB3A5 34208 3.37E-05 0.000242 VAMP2,SYT1,RAB3A

13 34208 3.33E-05 0.0002474 HIP1,MYO6,AP1B1,AP1G145 34208 5.78E-05 0.0004009 FLNB,ILK,MYH10,SEPT7,SORBS1,ACTN166 34208 6.31E-05 0.0004306 SIRT1,MTOR,TP53,SUMO1,MAX,USP7,TP53INP146 34208 6.56E-05 0.0004407 AP2A2,APP,MYO6,SNAP91,AP2B1,AP2A1

6 34208 6.67E-05 0.0004411 ARFGAP1,ZDHHC17,GJA1174 34208 7.57E-05 0.0004925 RPL7,DNAJC21,RPL23,RPL15,RPL14,RPL13,MRPS5,GCN1L1,RPL6,RPLP2,RPS6

16 34208 8.19E-05 0.0005246 ATP5B,ATP5C1,ATP5F1,ATP5A169 34208 8.41E-05 0.0005309 PPP1CA,GRIN2A,MYH10,ADD1,APP,DRD1,NR3C1

279 34208 0.000104 0.0006461 SREBF2,ATP2A2,BCL2,CNR1,CYP2C8,DNAJC1,FADS1,ITPR1,CPT1B,TSC2,HMGCR,ATP1A1,PPP1R3D,CASP77 34208 0.000115 0.0007079 CCT4,CCT2,TCP1

217 34208 0.00013 0.000786 PAFAH1B1,DPYSL2,ILK,MYH10,MBP,MTOR,DRD1,NEGR1,ADORA2A,PDE1B,TSC2,SNAP25219 34208 0.000142 0.0008444 TFEB,XRCC6,SIN3A,CTBP1,LMO4,TRRAP,CTNNB1,MED23,POU3F2,ARNTL,NCOR1,CREBBP

54 34208 0.000163 0.00096 MAPK1,CAV1,DRD1,CDH13,TSC2,ATP1B135 34208 0.000174 0.0010095 ATP5B,HSPA9,HADHA,VDAC2,VDAC1

8 34208 0.000183 0.0010303 DBN1,KAT2B,STX1A8 34208 0.000183 0.0010303 GRIN2A,GRIN1,EPS8

20 34208 0.000208 0.0011559 TP53,TAF4,TAF4B,TBP107 34208 0.00023 0.0012328 PAFAH1B1,SIRT1,GNAZ,NUP98,ITPR1,TPR,NUP160,NUP62

2 34208 0.000229 0.0012412 ASXL1,BAP12 34208 0.000229 0.0012412 ATP5B,ATP5C1

21 34208 0.000253 0.0013403 PAFAH1B1,YWHAZ,DCTN1,TUBG19 34208 0.000271 0.0014149 AP2A2,EGFR,AP2A1

113 34208 0.000334 0.0017235 PAFAH1B1,MYH10,AKT1,NUMA1,SEPT7,CLTC,MAD1L1,ATM280 34208 0.000384 0.0019124 GRB2,ZFYVE27,NGFR,SNX25,CAV1,VPS39,GGA3,EGFR,TRAF3,RAPGEF1,SH3GL3,VPS35,SNAP25

10 34208 0.000383 0.0019272 PAFAH1B1,MAPK1,YWHAE10 34208 0.000383 0.0019272 SIRT1,HDAC2,EZH1

287 34208 0.000485 0.0023861 HIP1,SREBF2,SYP,VAMP2,SYT1,CAV1,APP,ZDHHC17,AP1B1,AP1G1,ATP6V0A1,CLTC,STX1A44 34208 0.000521 0.002505 PAFAH1B1,MAPK1,TP53,RAB3A,CAPN211 34208 0.00052 0.0025298 CTNNB1,GJA1,ACTN193 34208 0.000541 0.0025713 ILK,CSK,MLLT4,RAP1B,ADD3,CTNNB1,TLN168 34208 0.000579 0.0027236 SIRT1,PAX6,SMARCA4,TP53,NCOR1,CREBBP46 34208 0.000642 0.0029827 SYN1,SYP,VAMP2,SYT1,STX1A

3 34208 0.00068 0.0029949 STX1A,SNAP253 34208 0.00068 0.0029949 XPC,RAD23B3 34208 0.00068 0.0029949 SYT1,RAB3A

3 34208 0.00068 0.0029949 CTNNB1,SORBS147 34208 0.000709 0.0030927 GRIN2A,SYP,SYT1,ADORA2A,SNAP9170 34208 0.000677 0.0031117 SYP,SYT1,RAB3A,GRIN1,SNAP91,PCLO71 34208 0.00073 0.0031506 VAMP2,RAB11A,GGA3,AP2B1,BECN1,SNAP2548 34208 0.000782 0.0033409 MYO9B,MYH10,MYO6,MYL6,MYO5A

101 34208 0.000886 0.003747 PTK2B,CTNNB1,AKT1,CAPZB,INPPL1,GSN,SNAP2529 34208 0.000914 0.0038283 NCOR2,HDAC3,HDAC1,NCOR1

132 34208 0.000938 0.0038879 RPL7,SNRNP200,HSPA8,DDX5,EFTUD2,NUP62,YBX1,RPS631 34208 0.001182 0.0048559 NSF,ILK,APP,CTNNB1

4 34208 0.001346 0.0054213 NFYA,NFYC4 34208 0.001346 0.0054213 CAMK2G,CAMK1D

15 34208 0.001372 0.0054731 HDAC2,HDAC1,CHD316 34208 0.001669 0.0065984 COL4A5,ENTPD2,ENTPD1

179 34208 0.001715 0.0067184 CTSD,MTOR,FNBP1,TRIP10,RAB14,GJA1,GOT1,NUP62,CTNS17 34208 0.002004 0.0077067 TUBB,GFAP,CASP859 34208 0.001996 0.0077442 EZR,APP,CTNNB1,NUMA1,TUBG1

297 34208 0.002079 0.0079209 ATP5B,NGFR,CAV1,APP,ENTPD6,USP14,HSPA8,PPFIA3,GPM6A,HSPA9,HSPA2,HMGB15 34208 0.00222 0.0081671 CLTC,SNAP915 34208 0.00222 0.0081671 ATP5C1,ATP5A15 34208 0.00222 0.0081671 AP1G1,GGA35 34208 0.00222 0.0081671 DNM2,MYO6

262 34208 0.002339 0.0085287 PAFAH1B1,DYNC1H1,FEZ1,TUBB,DNM2,KIF5C,DYNC1I2,TEKT1,TBCD,DNM1,DCTN1122 34208 0.002633 0.0095192 MAPK1,SNX27,RAB14,GJA1,NISCH,USP8,CTNS

39 34208 0.00281 0.0099052 TJP2,MLLT4,TBCD,CTNNB139 34208 0.00281 0.0099052 HIP1,VAMP2,AP1G1,CLTC64 34208 0.002858 0.0099898 MAPK1,HTT,RAB14,CTNS,SQSTM119 34208 0.002792 0.0100101 PAFAH1B1,YWHAE,KIF5C

158 34208 0.002919 0.0101201 FEZ1,GFAP,NCKAP1,ZFYVE27,MBP,TRIP10,NDRG2,ACTN140 34208 0.003085 0.0106106 GRIN2A,DPYSL2,ILK,PFN2

196 34208 0.00316 0.0107809 ANXA6,EZR,CAV1,PFKM,PRKAA2,SEPT7,RAB14,ATP1B1,AP2A16 34208 0.003297 0.010982 PRPF8,SNRNP2006 34208 0.003297 0.010982 HSPA8,ALDOA6 34208 0.003297 0.010982 TRRAP,KAT2B

129 34208 0.003592 0.0118689 EZR,CAV1,CTNNB1,EGFR,ATP1A1,ATP1B1,AP2A197 34208 0.003626 0.011889 FEZ1,AKT1,SEPT7,MYCBP2,LANCL1,INPP5B42 34208 0.00369 0.0120071 CHCHD4,NDUFS1,NDUFA8,ARL221 34208 0.003748 0.0120098 MYO9B,MYO6,ACTB

201 34208 0.00373 0.0120454 ATP5B,ATP5C1,NR3C1,ATP5F1,SUCLA2,HADHA,DLD,ATP5A1,ME222 34208 0.004291 0.0136478 ATP2A2,CAMK2G,CAMK2B

7 34208 0.00457 0.0139069 CTNNB1,GSK3B7 34208 0.00457 0.0139069 CLTC,AP2A17 34208 0.00457 0.0139069 PPP1CA,PPP1R3D7 34208 0.00457 0.0139069 ATP1A1,ATP1B17 34208 0.00457 0.0139069 MYO6,MYL6

134 34208 0.004424 0.0139654 SF3A3,SRRM2,PRPF8,EP400,SUMO1,CRNKL1,EFTUD223 34208 0.00488 0.0147442 CACNA1E,PPM1A,CACNA2D124 34208 0.005515 0.016545 SF3B3,SF3B2,YBX175 34208 0.005651 0.0168347 CEP63,CTNNB1,NUMA1,DCTN1,NUP62

8 34208 0.006032 0.0171252 CUL2,CUL18 34208 0.006032 0.0171252 CTNNB1,SORBS18 34208 0.006032 0.0171252 PPP1CA,OGT8 34208 0.006032 0.0171252 SYP,DLG48 34208 0.006032 0.0171252 SNW1,NCOR18 34208 0.006032 0.0171252 ATP2A2,ITPR1

25 34208 0.006197 0.0174766 TBCD,CTNNB1,ARL248 34208 0.005975 0.0176741 EZR,DIAPH1,MYO6,TLN1

145 34208 0.00676 0.018938 TRAF6,SNX25,AP3D1,ATP6V0A1,GGA3,EGFR,ATP6V0E126 34208 0.006928 0.0191538 ATP2A2,ITPR1,CACNA2D126 34208 0.006928 0.0191538 NCOR2,TP53,CREBBP

9 34208 0.007678 0.0206876 SEC24C,SEC23A9 34208 0.007678 0.0206876 KIF5C,APP9 34208 0.007678 0.0206876 SYN1,ADORA2A

265 34208 0.007554 0.0207482 XRCC6,SSRP1,RBM19,NUMA1,SEPT7,MAD1L1,TPR,BUB3,WHSC1,HIST1H2AC28 34208 0.008537 0.0228545 CHD8,TAF4,MAX83 34208 0.008621 0.0229346 AP1B1,AP1G1,ATP6V0A1,HTT,CLTC10 34208 0.009502 0.0248115 NUP98,NUP16010 34208 0.009502 0.0248115 SP1,CTNNB129 34208 0.009416 0.0248941 VPRBP,WDR6,ATP5A186 34208 0.009969 0.02587 MAPK1,CCT4,CEP250,TCP1,CAMK2B30 34208 0.010347 0.0263653 HDAC3,NUMA1,NCOR130 34208 0.010347 0.0263653 NSF,GALNT2,RAB1430 34208 0.010347 0.0263653 GNAZ,DLG4,GNAI211 34208 0.011498 0.0281143 DYNC1H1,DCTN111 34208 0.011498 0.0281143 TRAF6,TRAF311 34208 0.011498 0.0281143 SMARCA4,SMARCC211 34208 0.011498 0.0281143 SIRT1,TBP11 34208 0.011498 0.0281143 CAPZA1,CAPZB

123 34208 0.011256 0.0285099 VPS39,AP1B1,AP1G1,SPHK2,SLC15A4,CTNS31 34208 0.011329 0.0285236 CAV1,LDHA,DLD32 34208 0.012362 0.0300532 SEC24C,SREBF2,SEC23A93 34208 0.013661 0.0319264 SYMPK,TJP2,VAPA,TBCD,CLDN1261 34208 0.013749 0.0319555 SEPT7,MAD1L1,TPR,BUB312 34208 0.013661 0.0321027 GRIN2A,GRIN112 34208 0.013661 0.0321027 PPM1F,PPM1A12 34208 0.013661 0.0321027 MAPK1,ACTN112 34208 0.013661 0.0321027 SMARCA4,SMARCC212 34208 0.013661 0.0321027 MAPK1,DLG412 34208 0.013661 0.0321027 APP,CAMK2B

1 34208 0.015143 0.0335358 NOP141 34208 0.015143 0.0335358 NUP621 34208 0.015143 0.0335358 ADORA2A1 34208 0.015143 0.0335358 PIK3R11 34208 0.015143 0.0335358 NACA1 34208 0.015143 0.0335358 MTOR1 34208 0.015143 0.0335358 MARCKS1 34208 0.015143 0.0335358 ATP5B

1 34208 0.015143 0.0335358 PAFAH1B1170 34208 0.015313 0.0337369 GRIN2A,DNM2,GPHN,GRIN1,ADORA2A,DLG4,SNAP91

13 34208 0.015984 0.0348521 SYN1,HSPA213 34208 0.015984 0.0348521 MTOR,PIK3R136 34208 0.017024 0.0367399 GNAZ,GNB1,GNAI236 34208 0.017024 0.0367399 TRAF6,CTNNB1,TRAF366 34208 0.017908 0.0384521 ATP5B,SPG7,NDUFS3,CASP714 34208 0.018463 0.0386632 TRRAP,EP40014 34208 0.018463 0.0386632 TRRAP,TAF414 34208 0.018463 0.0386632 TCP1,TUBG114 34208 0.018463 0.0386632 EZR,CTNNB137 34208 0.018322 0.0391422 MYH10,RAB11A,SEPT715 34208 0.021093 0.0428954 SIRT1,TCP115 34208 0.021093 0.0428954 ALDOA,KAT2B15 34208 0.021093 0.0428954 MBP,BCL215 34208 0.021093 0.0428954 SMARCA4,SMARCC215 34208 0.021093 0.0428954 KAT2B,CHD339 34208 0.021079 0.043923 COL4A5,MYH10,APP

105 34208 0.021945 0.0444158 MYO6,USP14,FNBP1,BECN1,ATM16 34208 0.023868 0.0480761 VAMP2,ITPR1

PAFAH1B1,FLNB,PARK2,SGK1,TFEB,GRB2,SP1,UBR4,HIP1,GPI,VPRBP,SEC24C,XRCC6,CASP2,UBE2K,SREBF2,NFKB1,NSF,DYNC1H1,SIRT1,MYO9B,EDC4,TNFRSF8,SYMPK,CASP6,PSMC2,FEZ1,MAPK1,PPP1CA,MED15,TUBB,ANXA6,BTG1,MARCKS,NEDD4L,TJP2,FMNL3,SSRP1,GFAP,EPB41L1,API5,DDX24,PAX6,EZR,DPYSL2,CCT4,ILK,CCT2,MAP3K10,DNM2,YWHAE,MYH10,GPHN,MLF1,ADD1,HDAC3,MTOR,TRIO,CTBP1,BCL2,EGR1,SYT1,KIF5C,TRAF6,BAIAP2,SPG20,YWHAH,RPL23,ARF4,TNIP1,ADAR,RPL14,G3BP2,FLII,PACSIN1,NGFR,HDLBP,CABIN1,CSK,CAPZA1,BAG1,DDB1,CAV1,CABLES1,PFKM,AP3D1,PTK2B,HMGB2,DIAPH1,DNAJB1,PRKRA,SNX27,APP,ARFGAP1,WDR6,LDHA,NACA,PTK6,FABP5,MAGED1,TGM2,STIP1,ZDHHC17,SRRT,MYO6,TPM2,YWHAZ,VPS39,MLLT4,TP53,DBN1,RASA1,EEF1A1,TAF4,USP14,PRKAA2,RAB3A,AASDHPPT,PIK3R1,RAP1B,CAPN2,CEP63,DYNC1I2,PPL,ARPC1A,GMDS,ADD3,HSPA8,PSMD8,DNM1L,TEKT1,USP21,CEP250,RBM19,TBCD,TCP1,AP1G1,HDAC2,CTH,FNBP1,BCAS4,MLF2,FNTA,ITPR1,NR3C1,SMG5,PPFIA3,STXBP1,CTNNB1,TYK2,MCM3AP,AKT1,GIT1,ATP6V0A1,TRIP10,TAF4B,CAPZB,HSPA4,HDAC1,PDE1B,HUWE1,CAMK2B,DNM1,HSPA9,HADHA,NUMA1,PPP1R13B,SEPT7,HTT,CAMK1D,DCTN1,GJA1,REST,SNCA,CDH13,ZFP36L2,UBQLN2,TUBG1,INPPL1,MAD1L1,TPR,APAF1,SUMO1,TRAF1,ADD2,UBQLN1,RAD51C,SORBS1,USP9X,CHD3,DLD,PSMA1,SIN3B,TSC2,FHOD3,XPC,EGFR,RAD23B,DUSP8,CBS,SPHK2,PGM1,TRAF3,NISCH,ARHGAP1,MAX,ACTB,CAPZA2,CYFIP2,USP7,NDRG2,YWHAB,CRNKL1,ACTR1B,GOT1,DLG4,TBP,CASP1,GSK3B,ARHGEF6,LANCL1,INPP5B,EFTUD2,PFN2,NUP62,BECN1,ACTN1,GCN1L1,GNAI2,CASP7,EWSR1,YBX1,PSPC1,RECQL5,CASK,SH3GL3,USP8,TMOD2,GSN,UCHL3,NCOR1,NXT2,UPF1,GSTP1,BAP1,VPS35,SQSTM1,TLN1,YWHAG,NUP153,SNAP25,CREBBP,ATM,WHSC1,ARL2,UGP2,CASP3,OGT,CASP8,RPS6,GAPDH,CORO1B,HMGB1PAFAH1B1,PARK2,GRB2,GPI,SEC24C,CASP2,PPP2R2A,NFKB1,AP2A2,NAPA,NSF,DYNC1H1,SRGAP1,MYO9B,EDC4,CASP6,PSMC2,MAPK1,EIF2AK2,PPP1CA,TUBB,Ube3a,EPB41L1,SRGAP2,EZR,DPYSL2,CCT4,ILK,CCT2,RPL7,DNM2,YWHAE,ADD1,MTOR,TRIO,BCL2,TRAF6,BAIAP2,USP19,ARHGAP18,RPL23,RPL15,RPL14,RPL13,G3BP2,NGFR,CSK,CAPZA1,BAG1,CAV1,CABLES1,PFKM,PTK2B,SNX27,APP,ARFGAP1,LDHA,PAICS,MYO6,TPM2,YWHAZ,MLLT4,TP53,RASA1,EEF1A1,RANBP2,CAMK2G,PRKAA2,AASDHPPT,PIK3R1,RAP1B,CEP63,DYNC1I2,HSPA8,PSMD8,DNM1L,CEP250,NUP98,AP1B1,TCP1,ALDOA,AP1G1,FNTA,NR3C1,SMG5,STXBP1,CTNNB1,TYK2,MCM3AP,AKT1,THY1,TRIP10,CAPZB,HSPA4,HDAC1,PDE1B,CAMK2B,NUMA1,HTT,RAB14,DCTN1,PPM1A,REST,SNCA,TUBG1,FABP3,PAH,CLTC,INPPL1,MAD1L1,APAF1,ANAPC1,SORBS1,NUP160,PSMA1,TSC2,CBS,SPHK2,PGM1,TRAF3,NISCH,ARHGAP1,CUL1,BUB3,ACTB,CAPZA2,NDRG2,YWHAB,ASNS,GOT1,MYL6,CASP1,GSK3B,AP2B1,RAC1,SEC23A,ARHGEF6,RAPGEF1,INPP5B,ACTN1,RPL6,GNAI2,CASP7,MAT2A,USP8,GSN,ARHGEF7,RPLP2,UPF1,GSTP1,VPS35,SQSTM1,TLN1,YWHAG,AP2A1,ARL2,UGP2,GSS,CASP3,OGT,CASP8,RPS6,GAPDH,PSMD3PAFAH1B1,MECP2,FLNB,PARK2,ELK1,SGK1,TFEB,GRB2,SP1,UBR4,HIP1,GPI,VPRBP,SEC24C,XRCC6,ZNF292,CASP2,SREBF2,SF3A3,NFKB1,SFMBT2,SIRT1,EDC4,SYMPK,CASP6,PSMC2,MAPK1,PPP1CA,NCOR2,SRRM2,MED15,Ube3a,BTG1,TJP2,SSRP1,API5,PAX6,BCL11B,SIN3A,CCT4,COX4I1,CCT2,NFYA,GTF3C5,DNM2,MLF1,ADD1,HDAC3,MTOR,CTBP1,BCL2,EGR1,TRAF6,BAIAP2,ZNF207,DUSP2,ASXL1,TNIP1,ADAR,TRRAP,BATF,FLII,PRPF8,SNRNP200,NGFR,HDLBP,CABIN1,BAG1,DDB1,CABLES1,RNGTT,PTK2B,HMGB2,DOT1L,CHD8,DNAJB1,DRD1,POU2AF1,SF3B3,KIAA0556,NACA,PTK6,STIP1,SRRT,MYO6,YWHAZ,MLLT4,SMARCA4,MAF,SRCAP,TP53,CREBL2,EEF1A1,RANBP2,MEF2D,TAF4,PRKAA2,PIK3R1,RBM5,EP400,DNAJC1,CAPN2,PPL,POLR3E,PSMD8,USP21,RBM19,NUP98,DDX5,TCP1,HDAC2,EZH1,FADS1,CTH,MLF2,NR3C1,SMG5,SUPT5H,CTNNB1,TYK2,MCM3AP,AKT1,ATP6V0A1,TAF4B,HSPA4,MED23,HDAC1,PDE1B,HUWE1,POU3F2,SBF1,NUMA1,PPP1R13B,SEPT7,SNW1,KAT2B,HTT,CAMK1D,PPM1A,REST,SNCA,ZFP36L2,UBQLN2,MAD1L1,TPR,APAF1,SUMO1,SF3B2,CPT2,UBQLN1,RAD51C,ANAPC1,SORBS1,CHD3,NUP160,PSMA1,SIN3B,PPIL2,TSC2,FHOD3,XPC,EGFR,RAD23B,USP1,DUSP8,CBS,MAX,BUB3,USP7,NDRG2,YWHAB,CRNKL1,MYCBP2,MYEF2,BMP2K,CBFA2T2,TP53INP1,GSK3B,ARNTL,LANCL1,EFTUD2,ZNF91,NUP62,ACTN1,GNAI2,EWSR1,YBX1,PSPC1,RECQL5,CASK,ZNF24,USP8,SUGP2,UCHL3,NCOR1,ZMYND8,DHX8,NXT2,GSTP1,BAP1,SQSTM1,NFYC,NUP153,CREBBP,ATM,WHSC1,ARL2,SMARCC2,CASP3,OGT,CASP8,RPS6,RNMT,GAPDH,NOP14,PPP1R16B,HIST1H2AC,HMGB1XRCC6,SF3A3,NFKB1,SIRT1,SYMPK,CASP6,PSMC2,MAPK1,PPP1CA,NCOR2,MED15,SSRP1,SIN3A,GTF3C5,HDAC3,EGR1,DUSP2,ADAR,PRPF8,SNRNP200,NGFR,DDB1,RNGTT,HMGB2,SF3B3,SRRT,MYO6,YWHAZ,TP53,CAMK2G,TAF4,PRKAA2,RBM5,POLR3E,PSMD8,RBM19,NUP98,HDAC2,NR3C1,SUPT5H,AKT1,TAF4B,MED23,HDAC1,CAMK2B,NUMA1,SNW1,KAT2B,TPR,SUMO1,SF3B2,RAD51C,ANAPC1,PSMA1,SIN3B,XPC,RAD23B,USP1,CUL1,TBP,EFTUD2,CASP7,YBX1,PSPC1,RECQL5,NCOR1,SQSTM1,NUP153,CREBBP,ATM,CASP3,RNMT,PSMD3,HMGB1PAFAH1B1,SP1,GPI,SEC24C,SF3A3,NFKB1,SIRT1,SYMPK,PSMC2,PPP1CA,NCOR2,SRRM2,API5,DDX24,PAX6,EZR,SIN3A,CCT4,CCT2,CTBP1,TRAF6,BAIAP2,RPL23,ZNF207,ADAR,TRRAP,FLII,SNRNP200,CABIN1,PTK2B,HMGB2,DNAJB1,KIAA0556,PTK6,MLLT4,TP53,MEF2D,TAF4,RBM5,POLR3E,PSMD8,RBM19,DDX5,TCP1,EZH1,ITPR1,NR3C1,SUPT5H,ATP6V0A1,TAF4B,HSPA4,HDAC1,PDE1B,HUWE1,HADHA,NUMA1,PPP1R13B,SEPT7,SNW1,HTT,REST,APAF1,SF3B2,CPT2,SORBS1,PSMA1,PPIL2,FHOD3,RAD23B,CBS,MAX,BUB3,NDRG2,YWHAB,MYEF2,BMP2K,GSK3B,EFTUD2,PSPC1,RECQL5,BAP1,NUP153,WHSC1,SMARCC2,CASP3,OGT,RPS6,RNMT,NOP14,HMGB1PARK2,GRB2,NFKB1,MAPK1,ANXA6,SYP,DPYSL2,ATP2A2,ILK,CAV1,HMGB2,CHD8,WDR6,MAGED1,STIP1,YWHAZ,SRCAP,TP53,RAB3A,CEP250,RAB11A,ITPR1,NR3C1,STXBP1,HTT,UBQLN1,TSC2,ACTB,STX1A,BECN1,GSN,GSTP1,NUP153,CASP8FLNB,SGK1,GPI,AP2A2,SLC41A1,NSF,MICA,TNFRSF8,SYMPK,ATP5B,FEZ1,GRIN2A,MARCKS,RASD2,TJP2,EPB41L1,EZR,VAMP2,ILK,GNAZ,DNM2,MYH10,NCKAP1,GPHN,ZFYVE27,MBP,ADD1,SYT1,TRAF6,BAIAP2,ARF4,TNFSF13B,NGFR,HDLBP,RAB10,CNR1,CSK,CAV1,CACNA1E,PTK2B,DIAPH1,APP,DRD1,KIAA0556,PTK6,NEGR1,MAGED1,SLC2A3,TGM2,MYO6,MLLT4,RAB28,RASA1,CAMK2G,VAPA,USP14,RAB3A,PIK3R1,RAP1B,CAPN2,PPL,GRIN1,ADD3,HSPA8,TBCD,RAB11A,AGPAT3,TCP1,FNBP1,ITPR1,ADORA2A,STXBP1,CTNNB1,AKT1,ENTPD3,THY1,ATP6V0A1,TRIP10,SLC16A1,GNB1,CAMK2B,PPP1R13B,SEPT7,RAB14,GJA1,SNCA,CDH13,UBQLN2,CNTN1,CLTC,INPPL1,CLDN12,ADD2,SORBS1,TMPRSS5,EGFR,KCNN3,ABCC10,NISCH,ARHGAP1,ATP1A1,DLG4,SNAP91,GSK3B,AP2B1,RAC1,CD22,STX1A,ATP5A1,ACTN1,ATP1B1,GNAI2,EWSR1,CASK,USP8,WNT10A,GSTP1,TLN1,KCNC1,VDAC1,SNAP25,AP2A1,ENTPD1,CASP3,OGT,PPP1R16BPARK2,NDUFV1,SGK1,CASP2,NFKB1,SLC25A3,PSMC2,ATP5B,FEZ1,MAPK1,SLC25A4,DPYSL2,COX4I1,UQCRC2,YWHAE,MTOR,BCL2,SPG7,MRPS5,NDUFV2,BAG1,CAV1,LDHA,TGM2,YWHAZ,TRAP1,TOMM22,TP53,COX6C,PPL,RAB11A,ECH1,ATP5C1,STXBP1,ATP5F1,SUCLA2,SLC16A1,HSPA9,HADHA,NDUFS3,SLC25A11,VDAC3,CPT1B,CLTC,MAD1L1,CPT2,RAD51C,CHCHD4,DLD,SLC25A12,TRAF3,VDAC2,ATP5A1,GLOD4,NDUFS1,NDUFB10,UCHL3,NDUFA8,VDAC1,NDUFB8,SLC25A13,ARL2,ME2,CASP3,CASP8,NOP14,HSPA2PAFAH1B1,UBR4,HIP1,DYNC1H1,SYMPK,MAPK1,TUBB,EPB41L1,EZR,CCT4,DNM2,GPHN,ADD1,KIF5C,FLII,CAPZA1,PTK2B,DIAPH1,TPM2,CEP63,DYNC1I2,PPL,ARPC1A,ADD3,TEKT1,CEP250,TCP1,FNBP1,CTNNB1,TYK2,TRIP10,CAPZB,CAMK2B,DNM1,DCTN1,SNCA,TUBG1,INPPL1,ADD2,SORBS1,CHD3,FHOD3,ACTB,ACTR1B,NUP62,ACTN1,GNAI2,TMOD2,ARL2,PCLOPAFAH1B1,PARK2,SEC24C,MYO9B,ANXA6,VAMP2,TRAF6,BAG1,CAV1,PTK2B,HMGB2,PRKRA,APP,GALNT2,MYO6,YWHAZ,VAPA,CEP250,CTNNB1,TRIP10,RAB14,UBQLN1,RAD51C,TSC2,EGFR,CYFIP2,NDRG2,YWHAB,SEC23A,GSN,NCOR1,SNAP25,RPS6,GAPDHFLNB,MYO9B,MARCKS,EZR,BAIAP2,CAPZA1,DBN1,ARPC1A,ALDOA,CORO1C,CAPZB,SEPT7,SNCA,MAD1L1,PGM1,ACTB,CAPZA2,PFN2,CASK,GSN,TLN1,SNAP25,CORO1BGPI,GRIN2A,SYP,VAMP2,DPYSL2,APP,USP14,RAB3A,PIK3R1,GRIN1,NR3C1,SEPT7,SNCA,EPS8,CYFIP2,DLG4,STX1A,SNAP25PAFAH1B1,GPI,SYN1,CASP2,MAPK1,DPYSL2,MTOR,TNFSF13B,CAV1,PFKM,DNAJB1,WDR6,YWHAZ,USP14,RAB3A,PIK3R1,CAPN2,ADD3,DNAJA2,AKT1,CBS,ACTB,ASNS,GOT1,PPP1R3D,FBLN1,CASP7,SNAP25,UGP2,GSS,HMGB1SEC16A,PARK2,GRB2,HIP1,SYN1,SEC24C,SREBF2,DYNC1H1,MAPK1,MED15,COG1,MTOR,ARF4,RAB10,CSK,CAV1,AP3D1,APP,ARFGAP1,ENTPD6,STIP1,ZDHHC17,GALNT2,MYO6,B4GALT6,SRCAP,DNM1L,AP1B1,TCP1,AP1G1,ATP6V0A1,TRIP10,CALU,HTT,RAB14,GJA1,INPPL1,APAF1,TSC2,EGFR,GCNT1,NDRG2,MYEF2,SEC23A,BECN1,MGAT1,ARL2PAFAH1B1,FLNB,MYO9B,MARCKS,EZR,MYH10,TRAF6,CAV1,PTK2B,MYO6,ADD3,FNBP1,CTNNB1,TRIP10,SEPT7,SNCASP1,ZNF292,CASP2,SF3A3,SRGAP1,EIF2AK2,Ube3a,NEDD4L,TBC1D5,SRGAP2,BCL11B,EZR,RPL7,TRIO,BCL2,DNAJC21,EGR1,ARHGAP18,TBC1D22A,RPL15,ZNF207,ARF4,TNIP1,ADAR,RPL14,RPL13,G3BP2,MRPS5,CAV1,PRKRA,GSPT1,DBN1,RASA1,PIK3R1,RBM5,RAP1B,CAPN2,GMDS,HSPA8,NR3C1,HUWE1,RAB14,REST,GGA3,APAF1,GBF1,TSC2,EGFR,ARHGAP1,CRNKL1,CASP1,ARHGEF6,RAPGEF1,INPP5B,ZNF91,RPL6,EWSR1,ZNF24,USP8,SUGP2,ARHGEF7,RPLP2,UCHL3,NXT2,GSTP1,BAP1,NFYC,NUP153,ARL2,SMARCC2,RPS6PAFAH1B1,DYNC1H1,FEZ1,MARCKS,ODF2L,FLII,CSK,CEP63,DYNC1I2,CEP250,CTNNB1,DCTN1,TUBG1,MAD1L1,SORBS1,CHD3,PSMA1,NDRG2,YWHAB,ACTR1B,GSK3B,GNAI2,TLN1,ARL2,OGTPARK2,PPP1CA,GRIN2A,SYT1,KIF5C,DIAPH1,CTNNB1,PPM1A,CDH13,STX1A,SNAP25,CASP8,HMGB1NDUFV1,SLC25A3,SLC25A4,COX4I1,UQCRC2,NDUFV2,TOMM22,COX6C,ATP5C1,ATP5F1,HADHA,NDUFS3,SLC25A11,CPT2,SLC25A12,VDAC2,ATP5A1,NDUFS1,NDUFB10,NDUFA8,VDAC1,NDUFB8,SLC25A13

SEC16A,PAFAH1B1,NDUFV1,GRB2,UBR4,HIP1,SEC24C,SREBF2,AP2A2,NAPA,MICA,SLC25A3,SLC25A4,DNAJA1,SLC35F5,SYP,COG1,ATP2A2,COX4I1,UQCRC2,ADD1,MTOR,BCL2,SPG7,SYT1,USP19,NDUFV2,SNX25,AP3D1,CACNA1E,CYP2C8,ENTPD6,SORCS1,SLC2A3,ZDHHC17,GALNT2,VPS39,NAPB,TOMM22,B4GALT6,COX6C,DNAJC1,RAP1B,ADD3,DNM1L,ENTPD2,NUP98,AP1B1,KCNRG,DNAJA2,ATP5C1,AP1G1,FADS1,ITPR1,NR3C1,ATP5F1,CTNNB1,TYK2,ASPH,GPM6A,CAPZB,NDUFS3,SLC25A11,CDH13,VDAC3,CPT1B,GGA3,KIAA0922,TPR,SUMO1,CPT2,ADD2,TMPRSS5,TSC2,EGFR,SLC25A12,HMGCR,SPHK2,PIGM,GCNT1,CAPZA2,ATP1A1,CACNA2D1,AP2B1,RAC1,SEC23A,CD22,LANCL1,SEC61A2,INPP5B,STX1A,ATP6V0E1,VDAC2,BECN1,ATP1B1,NDUFS1,SGPP2,BCAN,SH3GL3,SLC15A4,POMT2,MGAT1,NDUFB10,CTNS,VPS35,VDAC1,NDUFB8,SLC25A13,PCLO,GAPDHANXA6,CCT4,CTSD,YWHAE,YWHAZ,HSPA8,PPIB,ATP6V0A1,CALU,CLTC,ATP1A1,YWHAB,RAC1AP2A2,VAMP2,SYT1,CAV1,CAMK2G,CAMK2B,DLG4,AP2B1,AP2A1NCOR2,SIN3A,HDAC3,CTBP1,REST,YWHAB,NCOR1,SMARCC2,HMGB1

SYN1,GRIN2A,SYP,VAMP2,DNM2,GPHN,ADD1,SYT1,APP,GRIN1,CTNNB1,SNCA,SUMO1,CYFIP2,DLG4,STX1A,BCAN,SNAP25,PCLO,RIMS4SYN1,SYMPK,GRIN2A,TJP2,SYP,VAMP2,DNM2,GPHN,SYT1,BAIAP2,MLLT4,PPL,GRIN1,TBCD,TCP1,CTNNB1,GJA1,SNCA,CLDN12,SORBS1,CYFIP2,DLG4,STX1A,SNAP25,PCLO,RIMS4SF3A3,SRRM2,PRPF8,SNRNP200,SF3B3,DDX5,SNW1,SF3B2,CRNKL1,EFTUD2,DHX8

SREBF2,FEZ1,DPYSL2,ZFYVE27,MTOR,NEGR1,DBN1,GRIN1,ADORA2A,THY1,HTT,SUMO1,TSC2,MAX,BCANPAFAH1B1,DPYSL2,MYH10,PTK2B,THY1,SNCA,TSC2,NDRG2,TMOD2,SNAP25PAFAH1B1,SIN3A,NUP98,KAT2B,DCTN1,MAD1L1,TPR,NUP160,BUB3PAFAH1B1,BCL2,TRAF6,MYO6,DNAJC1,NUP98,TPR,SUMO1,EGFR,NUP62,RECQL5,NUP153,WHSC1SF3A3,API5,SNRNP200,SF3B3,RBM5,SNW1,SF3B2,CRNKL1,EFTUD2,DHX8NDUFV1,UQCRC2,NDUFV2,NDUFS3,NDUFS1,NDUFB10,NDUFA8,NDUFB8FEZ1,DPYSL2,ILK,MYH10,ZFYVE27,PTK2B,APP,DRD1,ADORA2A,HTT,SNCA,ACTB,MYCBP2,SNAP25HIP1,XRCC6,CASP2,GFAP,ATP2A2,BCL2,DRD1,ENTPD6,FADS1,ADORA2A,CTNNB1,AKT1,SLC16A1,HTT,RAB14,PPM1A,GJA1,CNTN1,TSC2,SPHK2,NISCH,ATP1A1,ATP6V0E1,GNAI2,BCANGRIN2A,DNM2,PTK2B,YWHAZ,GRIN1,ITPR1,NR3C1,ADORA2A,EPS8,DLG4,SNAP91EZR,BAIAP2,PTK6,MYO6,RASA1,ARHGAP1,ACTN1,GSN,TLN1NDUFV1,NDUFV2,NDUFS3,NDUFS1,NDUFB10,NDUFA8,NDUFB8

SEC16A,SEC24C,SREBF2,COG1,DNM2,MTOR,CAV1,AP3D1,ENTPD6,ZDHHC17,B4GALT6,AP1B1,AP1G1,ADORA2A,RAB14,GJA1,GBF1,EGFR,GCNT1,SEC23A,MGAT1RANBP2,NUP98,MAD1L1,TPR,SUMO1,NUP160,NUP62,NUP153

SEC16A,PARK2,SGK1,SEC24C,SREBF2,GNAZ,ZFYVE27,MTOR,BCL2,USP19,CAV1,CYP2C8,DRD1,TP53,VAPA,DNAJC1,AGPAT3,KCNRG,PPIB,FADS1,ITPR1,ASPH,THY1,CALU,HTT,GJA1,UBQLN1,EGFR,HMGCR,PIGM,SEC23A,SEC61A2,SGPP2,POMT2,NDUFB8

SEC16A,SGK1,SEC24C,SREBF2,ATP2A2,ZFYVE27,MTOR,BCL2,USP19,CYP2C8,DRD1,VAPA,DNAJC1,AGPAT3,FADS1,ITPR1,ASPH,GJA1,EGFR,HMGCR,PIGM,SEC23A,SEC61A2,CASP7,SGPP2,POMT2

FLNB,MAPK1,EZR,ILK,CAV1,PTK2B,GIT1,SORBS1,ACTN1,TLN1

HIP1,SEC24C,CSK,APP,ZDHHC17,MEF2D,ATP6V0A1,CBS,ARHGAP1,LANCL1,NUP62,YBX1,BAP1,TLN1,ME2

SLC25A4,MTOR,BCL2,DNM1L,GJA1,VDAC3,CPT1B,VDAC2,VDAC1CAV1,PTK2B,ITPR1,THY1,GJA1,SORBS1,EGFR,GNAI2,SNAP25,CASP8

RPL7,DNAJC21,RPL23,RPL15,RPL14,RPL13,MRPS5,GCN1L1,RPL6,RPLP2,RPS6

SREBF2,ATP2A2,BCL2,CNR1,CYP2C8,DNAJC1,FADS1,ITPR1,CPT1B,TSC2,HMGCR,ATP1A1,PPP1R3D,CASP7

PAFAH1B1,DPYSL2,ILK,MYH10,MBP,MTOR,DRD1,NEGR1,ADORA2A,PDE1B,TSC2,SNAP25TFEB,XRCC6,SIN3A,CTBP1,LMO4,TRRAP,CTNNB1,MED23,POU3F2,ARNTL,NCOR1,CREBBP

PAFAH1B1,SIRT1,GNAZ,NUP98,ITPR1,TPR,NUP160,NUP62

PAFAH1B1,MYH10,AKT1,NUMA1,SEPT7,CLTC,MAD1L1,ATMGRB2,ZFYVE27,NGFR,SNX25,CAV1,VPS39,GGA3,EGFR,TRAF3,RAPGEF1,SH3GL3,VPS35,SNAP25

HIP1,SREBF2,SYP,VAMP2,SYT1,CAV1,APP,ZDHHC17,AP1B1,AP1G1,ATP6V0A1,CLTC,STX1A

RPL7,SNRNP200,HSPA8,DDX5,EFTUD2,NUP62,YBX1,RPS6

CTSD,MTOR,FNBP1,TRIP10,RAB14,GJA1,GOT1,NUP62,CTNS

ATP5B,NGFR,CAV1,APP,ENTPD6,USP14,HSPA8,PPFIA3,GPM6A,HSPA9,HSPA2,HMGB1

PAFAH1B1,DYNC1H1,FEZ1,TUBB,DNM2,KIF5C,DYNC1I2,TEKT1,TBCD,DNM1,DCTN1

FEZ1,GFAP,NCKAP1,ZFYVE27,MBP,TRIP10,NDRG2,ACTN1

ANXA6,EZR,CAV1,PFKM,PRKAA2,SEPT7,RAB14,ATP1B1,AP2A1

ATP5B,ATP5C1,NR3C1,ATP5F1,SUCLA2,HADHA,DLD,ATP5A1,ME2

XRCC6,SSRP1,RBM19,NUMA1,SEPT7,MAD1L1,TPR,BUB3,WHSC1,HIST1H2AC

PAFAH1B1,FLNB,PARK2,SGK1,TFEB,GRB2,SP1,UBR4,HIP1,GPI,VPRBP,SEC24C,XRCC6,CASP2,UBE2K,SREBF2,NFKB1,NSF,DYNC1H1,SIRT1,MYO9B,EDC4,TNFRSF8,SYMPK,CASP6,PSMC2,FEZ1,MAPK1,PPP1CA,MED15,TUBB,ANXA6,BTG1,MARCKS,NEDD4L,TJP2,FMNL3,SSRP1,GFAP,EPB41L1,API5,DDX24,PAX6,EZR,DPYSL2,CCT4,ILK,CCT2,MAP3K10,DNM2,YWHAE,MYH10,GPHN,MLF1,ADD1,HDAC3,MTOR,TRIO,CTBP1,BCL2,EGR1,SYT1,KIF5C,TRAF6,BAIAP2,SPG20,YWHAH,RPL23,ARF4,TNIP1,ADAR,RPL14,G3BP2,FLII,PACSIN1,NGFR,HDLBP,CABIN1,CSK,CAPZA1,BAG1,DDB1,CAV1,CABLES1,PFKM,AP3D1,PTK2B,HMGB2,DIAPH1,DNAJB1,PRKRA,SNX27,APP,ARFGAP1,WDR6,LDHA,NACA,PTK6,FABP5,MAGED1,TGM2,STIP1,ZDHHC17,SRRT,MYO6,TPM2,YWHAZ,VPS39,MLLT4,TP53,DBN1,RASA1,EEF1A1,TAF4,USP14,PRKAA2,RAB3A,AASDHPPT,PIK3R1,RAP1B,CAPN2,CEP63,DYNC1I2,PPL,ARPC1A,GMDS,ADD3,HSPA8,PSMD8,DNM1L,TEKT1,USP21,CEP250,RBM19,TBCD,TCP1,AP1G1,HDAC2,CTH,FNBP1,BCAS4,MLF2,FNTA,ITPR1,NR3C1,SMG5,PPFIA3,STXBP1,CTNNB1,TYK2,MCM3AP,AKT1,GIT1,ATP6V0A1,TRIP10,TAF4B,CAPZB,HSPA4,HDAC1,PDE1B,HUWE1,CAMK2B,DNM1,HSPA9,HADHA,NUMA1,PPP1R13B,SEPT7,HTT,CAMK1D,DCTN1,GJA1,REST,SNCA,CDH13,ZFP36L2,UBQLN2,TUBG1,INPPL1,MAD1L1,TPR,APAF1,SUMO1,TRAF1,ADD2,UBQLN1,RAD51C,SORBS1,USP9X,CHD3,DLD,PSMA1,SIN3B,TSC2,FHOD3,XPC,EGFR,RAD23B,DUSP8,CBS,SPHK2,PGM1,TRAF3,NISCH,ARHGAP1,MAX,ACTB,CAPZA2,CYFIP2,USP7,NDRG2,YWHAB,CRNKL1,ACTR1B,GOT1,DLG4,TBP,CASP1,GSK3B,ARHGEF6,LANCL1,INPP5B,EFTUD2,PFN2,NUP62,BECN1,ACTN1,GCN1L1,GNAI2,CASP7,EWSR1,YBX1,PSPC1,RECQL5,CASK,SH3GL3,USP8,TMOD2,GSN,UCHL3,NCOR1,NXT2,UPF1,GSTP1,BAP1,VPS35,SQSTM1,TLN1,YWHAG,NUP153,SNAP25,CREBBP,ATM,WHSC1,ARL2,UGP2,CASP3,OGT,CASP8,RPS6,GAPDH,CORO1B,HMGB1PAFAH1B1,PARK2,GRB2,GPI,SEC24C,CASP2,PPP2R2A,NFKB1,AP2A2,NAPA,NSF,DYNC1H1,SRGAP1,MYO9B,EDC4,CASP6,PSMC2,MAPK1,EIF2AK2,PPP1CA,TUBB,Ube3a,EPB41L1,SRGAP2,EZR,DPYSL2,CCT4,ILK,CCT2,RPL7,DNM2,YWHAE,ADD1,MTOR,TRIO,BCL2,TRAF6,BAIAP2,USP19,ARHGAP18,RPL23,RPL15,RPL14,RPL13,G3BP2,NGFR,CSK,CAPZA1,BAG1,CAV1,CABLES1,PFKM,PTK2B,SNX27,APP,ARFGAP1,LDHA,PAICS,MYO6,TPM2,YWHAZ,MLLT4,TP53,RASA1,EEF1A1,RANBP2,CAMK2G,PRKAA2,AASDHPPT,PIK3R1,RAP1B,CEP63,DYNC1I2,HSPA8,PSMD8,DNM1L,CEP250,NUP98,AP1B1,TCP1,ALDOA,AP1G1,FNTA,NR3C1,SMG5,STXBP1,CTNNB1,TYK2,MCM3AP,AKT1,THY1,TRIP10,CAPZB,HSPA4,HDAC1,PDE1B,CAMK2B,NUMA1,HTT,RAB14,DCTN1,PPM1A,REST,SNCA,TUBG1,FABP3,PAH,CLTC,INPPL1,MAD1L1,APAF1,ANAPC1,SORBS1,NUP160,PSMA1,TSC2,CBS,SPHK2,PGM1,TRAF3,NISCH,ARHGAP1,CUL1,BUB3,ACTB,CAPZA2,NDRG2,YWHAB,ASNS,GOT1,MYL6,CASP1,GSK3B,AP2B1,RAC1,SEC23A,ARHGEF6,RAPGEF1,INPP5B,ACTN1,RPL6,GNAI2,CASP7,MAT2A,USP8,GSN,ARHGEF7,RPLP2,UPF1,GSTP1,VPS35,SQSTM1,TLN1,YWHAG,AP2A1,ARL2,UGP2,GSS,CASP3,OGT,CASP8,RPS6,GAPDH,PSMD3PAFAH1B1,MECP2,FLNB,PARK2,ELK1,SGK1,TFEB,GRB2,SP1,UBR4,HIP1,GPI,VPRBP,SEC24C,XRCC6,ZNF292,CASP2,SREBF2,SF3A3,NFKB1,SFMBT2,SIRT1,EDC4,SYMPK,CASP6,PSMC2,MAPK1,PPP1CA,NCOR2,SRRM2,MED15,Ube3a,BTG1,TJP2,SSRP1,API5,PAX6,BCL11B,SIN3A,CCT4,COX4I1,CCT2,NFYA,GTF3C5,DNM2,MLF1,ADD1,HDAC3,MTOR,CTBP1,BCL2,EGR1,TRAF6,BAIAP2,ZNF207,DUSP2,ASXL1,TNIP1,ADAR,TRRAP,BATF,FLII,PRPF8,SNRNP200,NGFR,HDLBP,CABIN1,BAG1,DDB1,CABLES1,RNGTT,PTK2B,HMGB2,DOT1L,CHD8,DNAJB1,DRD1,POU2AF1,SF3B3,KIAA0556,NACA,PTK6,STIP1,SRRT,MYO6,YWHAZ,MLLT4,SMARCA4,MAF,SRCAP,TP53,CREBL2,EEF1A1,RANBP2,MEF2D,TAF4,PRKAA2,PIK3R1,RBM5,EP400,DNAJC1,CAPN2,PPL,POLR3E,PSMD8,USP21,RBM19,NUP98,DDX5,TCP1,HDAC2,EZH1,FADS1,CTH,MLF2,NR3C1,SMG5,SUPT5H,CTNNB1,TYK2,MCM3AP,AKT1,ATP6V0A1,TAF4B,HSPA4,MED23,HDAC1,PDE1B,HUWE1,POU3F2,SBF1,NUMA1,PPP1R13B,SEPT7,SNW1,KAT2B,HTT,CAMK1D,PPM1A,REST,SNCA,ZFP36L2,UBQLN2,MAD1L1,TPR,APAF1,SUMO1,SF3B2,CPT2,UBQLN1,RAD51C,ANAPC1,SORBS1,CHD3,NUP160,PSMA1,SIN3B,PPIL2,TSC2,FHOD3,XPC,EGFR,RAD23B,USP1,DUSP8,CBS,MAX,BUB3,USP7,NDRG2,YWHAB,CRNKL1,MYCBP2,MYEF2,BMP2K,CBFA2T2,TP53INP1,GSK3B,ARNTL,LANCL1,EFTUD2,ZNF91,NUP62,ACTN1,GNAI2,EWSR1,YBX1,PSPC1,RECQL5,CASK,ZNF24,USP8,SUGP2,UCHL3,NCOR1,ZMYND8,DHX8,NXT2,GSTP1,BAP1,SQSTM1,NFYC,NUP153,CREBBP,ATM,WHSC1,ARL2,SMARCC2,CASP3,OGT,CASP8,RPS6,RNMT,GAPDH,NOP14,PPP1R16B,HIST1H2AC,HMGB1XRCC6,SF3A3,NFKB1,SIRT1,SYMPK,CASP6,PSMC2,MAPK1,PPP1CA,NCOR2,MED15,SSRP1,SIN3A,GTF3C5,HDAC3,EGR1,DUSP2,ADAR,PRPF8,SNRNP200,NGFR,DDB1,RNGTT,HMGB2,SF3B3,SRRT,MYO6,YWHAZ,TP53,CAMK2G,TAF4,PRKAA2,RBM5,POLR3E,PSMD8,RBM19,NUP98,HDAC2,NR3C1,SUPT5H,AKT1,TAF4B,MED23,HDAC1,CAMK2B,NUMA1,SNW1,KAT2B,TPR,SUMO1,SF3B2,RAD51C,ANAPC1,PSMA1,SIN3B,XPC,RAD23B,USP1,CUL1,TBP,EFTUD2,CASP7,YBX1,PSPC1,RECQL5,NCOR1,SQSTM1,NUP153,CREBBP,ATM,CASP3,RNMT,PSMD3,HMGB1PAFAH1B1,SP1,GPI,SEC24C,SF3A3,NFKB1,SIRT1,SYMPK,PSMC2,PPP1CA,NCOR2,SRRM2,API5,DDX24,PAX6,EZR,SIN3A,CCT4,CCT2,CTBP1,TRAF6,BAIAP2,RPL23,ZNF207,ADAR,TRRAP,FLII,SNRNP200,CABIN1,PTK2B,HMGB2,DNAJB1,KIAA0556,PTK6,MLLT4,TP53,MEF2D,TAF4,RBM5,POLR3E,PSMD8,RBM19,DDX5,TCP1,EZH1,ITPR1,NR3C1,SUPT5H,ATP6V0A1,TAF4B,HSPA4,HDAC1,PDE1B,HUWE1,HADHA,NUMA1,PPP1R13B,SEPT7,SNW1,HTT,REST,APAF1,SF3B2,CPT2,SORBS1,PSMA1,PPIL2,FHOD3,RAD23B,CBS,MAX,BUB3,NDRG2,YWHAB,MYEF2,BMP2K,GSK3B,EFTUD2,PSPC1,RECQL5,BAP1,NUP153,WHSC1,SMARCC2,CASP3,OGT,RPS6,RNMT,NOP14,HMGB1PARK2,GRB2,NFKB1,MAPK1,ANXA6,SYP,DPYSL2,ATP2A2,ILK,CAV1,HMGB2,CHD8,WDR6,MAGED1,STIP1,YWHAZ,SRCAP,TP53,RAB3A,CEP250,RAB11A,ITPR1,NR3C1,STXBP1,HTT,UBQLN1,TSC2,ACTB,STX1A,BECN1,GSN,GSTP1,NUP153,CASP8FLNB,SGK1,GPI,AP2A2,SLC41A1,NSF,MICA,TNFRSF8,SYMPK,ATP5B,FEZ1,GRIN2A,MARCKS,RASD2,TJP2,EPB41L1,EZR,VAMP2,ILK,GNAZ,DNM2,MYH10,NCKAP1,GPHN,ZFYVE27,MBP,ADD1,SYT1,TRAF6,BAIAP2,ARF4,TNFSF13B,NGFR,HDLBP,RAB10,CNR1,CSK,CAV1,CACNA1E,PTK2B,DIAPH1,APP,DRD1,KIAA0556,PTK6,NEGR1,MAGED1,SLC2A3,TGM2,MYO6,MLLT4,RAB28,RASA1,CAMK2G,VAPA,USP14,RAB3A,PIK3R1,RAP1B,CAPN2,PPL,GRIN1,ADD3,HSPA8,TBCD,RAB11A,AGPAT3,TCP1,FNBP1,ITPR1,ADORA2A,STXBP1,CTNNB1,AKT1,ENTPD3,THY1,ATP6V0A1,TRIP10,SLC16A1,GNB1,CAMK2B,PPP1R13B,SEPT7,RAB14,GJA1,SNCA,CDH13,UBQLN2,CNTN1,CLTC,INPPL1,CLDN12,ADD2,SORBS1,TMPRSS5,EGFR,KCNN3,ABCC10,NISCH,ARHGAP1,ATP1A1,DLG4,SNAP91,GSK3B,AP2B1,RAC1,CD22,STX1A,ATP5A1,ACTN1,ATP1B1,GNAI2,EWSR1,CASK,USP8,WNT10A,GSTP1,TLN1,KCNC1,VDAC1,SNAP25,AP2A1,ENTPD1,CASP3,OGT,PPP1R16BPARK2,NDUFV1,SGK1,CASP2,NFKB1,SLC25A3,PSMC2,ATP5B,FEZ1,MAPK1,SLC25A4,DPYSL2,COX4I1,UQCRC2,YWHAE,MTOR,BCL2,SPG7,MRPS5,NDUFV2,BAG1,CAV1,LDHA,TGM2,YWHAZ,TRAP1,TOMM22,TP53,COX6C,PPL,RAB11A,ECH1,ATP5C1,STXBP1,ATP5F1,SUCLA2,SLC16A1,HSPA9,HADHA,NDUFS3,SLC25A11,VDAC3,CPT1B,CLTC,MAD1L1,CPT2,RAD51C,CHCHD4,DLD,SLC25A12,TRAF3,VDAC2,ATP5A1,GLOD4,NDUFS1,NDUFB10,UCHL3,NDUFA8,VDAC1,NDUFB8,SLC25A13,ARL2,ME2,CASP3,CASP8,NOP14,HSPA2PAFAH1B1,UBR4,HIP1,DYNC1H1,SYMPK,MAPK1,TUBB,EPB41L1,EZR,CCT4,DNM2,GPHN,ADD1,KIF5C,FLII,CAPZA1,PTK2B,DIAPH1,TPM2,CEP63,DYNC1I2,PPL,ARPC1A,ADD3,TEKT1,CEP250,TCP1,FNBP1,CTNNB1,TYK2,TRIP10,CAPZB,CAMK2B,DNM1,DCTN1,SNCA,TUBG1,INPPL1,ADD2,SORBS1,CHD3,FHOD3,ACTB,ACTR1B,NUP62,ACTN1,GNAI2,TMOD2,ARL2,PCLOPAFAH1B1,PARK2,SEC24C,MYO9B,ANXA6,VAMP2,TRAF6,BAG1,CAV1,PTK2B,HMGB2,PRKRA,APP,GALNT2,MYO6,YWHAZ,VAPA,CEP250,CTNNB1,TRIP10,RAB14,UBQLN1,RAD51C,TSC2,EGFR,CYFIP2,NDRG2,YWHAB,SEC23A,GSN,NCOR1,SNAP25,RPS6,GAPDHFLNB,MYO9B,MARCKS,EZR,BAIAP2,CAPZA1,DBN1,ARPC1A,ALDOA,CORO1C,CAPZB,SEPT7,SNCA,MAD1L1,PGM1,ACTB,CAPZA2,PFN2,CASK,GSN,TLN1,SNAP25,CORO1B

PAFAH1B1,GPI,SYN1,CASP2,MAPK1,DPYSL2,MTOR,TNFSF13B,CAV1,PFKM,DNAJB1,WDR6,YWHAZ,USP14,RAB3A,PIK3R1,CAPN2,ADD3,DNAJA2,AKT1,CBS,ACTB,ASNS,GOT1,PPP1R3D,FBLN1,CASP7,SNAP25,UGP2,GSS,HMGB1SEC16A,PARK2,GRB2,HIP1,SYN1,SEC24C,SREBF2,DYNC1H1,MAPK1,MED15,COG1,MTOR,ARF4,RAB10,CSK,CAV1,AP3D1,APP,ARFGAP1,ENTPD6,STIP1,ZDHHC17,GALNT2,MYO6,B4GALT6,SRCAP,DNM1L,AP1B1,TCP1,AP1G1,ATP6V0A1,TRIP10,CALU,HTT,RAB14,GJA1,INPPL1,APAF1,TSC2,EGFR,GCNT1,NDRG2,MYEF2,SEC23A,BECN1,MGAT1,ARL2

SP1,ZNF292,CASP2,SF3A3,SRGAP1,EIF2AK2,Ube3a,NEDD4L,TBC1D5,SRGAP2,BCL11B,EZR,RPL7,TRIO,BCL2,DNAJC21,EGR1,ARHGAP18,TBC1D22A,RPL15,ZNF207,ARF4,TNIP1,ADAR,RPL14,RPL13,G3BP2,MRPS5,CAV1,PRKRA,GSPT1,DBN1,RASA1,PIK3R1,RBM5,RAP1B,CAPN2,GMDS,HSPA8,NR3C1,HUWE1,RAB14,REST,GGA3,APAF1,GBF1,TSC2,EGFR,ARHGAP1,CRNKL1,CASP1,ARHGEF6,RAPGEF1,INPP5B,ZNF91,RPL6,EWSR1,ZNF24,USP8,SUGP2,ARHGEF7,RPLP2,UCHL3,NXT2,GSTP1,BAP1,NFYC,NUP153,ARL2,SMARCC2,RPS6PAFAH1B1,DYNC1H1,FEZ1,MARCKS,ODF2L,FLII,CSK,CEP63,DYNC1I2,CEP250,CTNNB1,DCTN1,TUBG1,MAD1L1,SORBS1,CHD3,PSMA1,NDRG2,YWHAB,ACTR1B,GSK3B,GNAI2,TLN1,ARL2,OGT

NDUFV1,SLC25A3,SLC25A4,COX4I1,UQCRC2,NDUFV2,TOMM22,COX6C,ATP5C1,ATP5F1,HADHA,NDUFS3,SLC25A11,CPT2,SLC25A12,VDAC2,ATP5A1,NDUFS1,NDUFB10,NDUFA8,VDAC1,NDUFB8,SLC25A13

SEC16A,PAFAH1B1,NDUFV1,GRB2,UBR4,HIP1,SEC24C,SREBF2,AP2A2,NAPA,MICA,SLC25A3,SLC25A4,DNAJA1,SLC35F5,SYP,COG1,ATP2A2,COX4I1,UQCRC2,ADD1,MTOR,BCL2,SPG7,SYT1,USP19,NDUFV2,SNX25,AP3D1,CACNA1E,CYP2C8,ENTPD6,SORCS1,SLC2A3,ZDHHC17,GALNT2,VPS39,NAPB,TOMM22,B4GALT6,COX6C,DNAJC1,RAP1B,ADD3,DNM1L,ENTPD2,NUP98,AP1B1,KCNRG,DNAJA2,ATP5C1,AP1G1,FADS1,ITPR1,NR3C1,ATP5F1,CTNNB1,TYK2,ASPH,GPM6A,CAPZB,NDUFS3,SLC25A11,CDH13,VDAC3,CPT1B,GGA3,KIAA0922,TPR,SUMO1,CPT2,ADD2,TMPRSS5,TSC2,EGFR,SLC25A12,HMGCR,SPHK2,PIGM,GCNT1,CAPZA2,ATP1A1,CACNA2D1,AP2B1,RAC1,SEC23A,CD22,LANCL1,SEC61A2,INPP5B,STX1A,ATP6V0E1,VDAC2,BECN1,ATP1B1,NDUFS1,SGPP2,BCAN,SH3GL3,SLC15A4,POMT2,MGAT1,NDUFB10,CTNS,VPS35,VDAC1,NDUFB8,SLC25A13,PCLO,GAPDH

SYN1,SYMPK,GRIN2A,TJP2,SYP,VAMP2,DNM2,GPHN,SYT1,BAIAP2,MLLT4,PPL,GRIN1,TBCD,TCP1,CTNNB1,GJA1,SNCA,CLDN12,SORBS1,CYFIP2,DLG4,STX1A,SNAP25,PCLO,RIMS4

HIP1,XRCC6,CASP2,GFAP,ATP2A2,BCL2,DRD1,ENTPD6,FADS1,ADORA2A,CTNNB1,AKT1,SLC16A1,HTT,RAB14,PPM1A,GJA1,CNTN1,TSC2,SPHK2,NISCH,ATP1A1,ATP6V0E1,GNAI2,BCAN

SEC16A,PARK2,SGK1,SEC24C,SREBF2,GNAZ,ZFYVE27,MTOR,BCL2,USP19,CAV1,CYP2C8,DRD1,TP53,VAPA,DNAJC1,AGPAT3,KCNRG,PPIB,FADS1,ITPR1,ASPH,THY1,CALU,HTT,GJA1,UBQLN1,EGFR,HMGCR,PIGM,SEC23A,SEC61A2,SGPP2,POMT2,NDUFB8

SEC16A,SGK1,SEC24C,SREBF2,ATP2A2,ZFYVE27,MTOR,BCL2,USP19,CYP2C8,DRD1,VAPA,DNAJC1,AGPAT3,FADS1,ITPR1,ASPH,GJA1,EGFR,HMGCR,PIGM,SEC23A,SEC61A2,CASP7,SGPP2,POMT2

PAFAH1B1,FLNB,PARK2,SGK1,TFEB,GRB2,SP1,UBR4,HIP1,GPI,VPRBP,SEC24C,XRCC6,CASP2,UBE2K,SREBF2,NFKB1,NSF,DYNC1H1,SIRT1,MYO9B,EDC4,TNFRSF8,SYMPK,CASP6,PSMC2,FEZ1,MAPK1,PPP1CA,MED15,TUBB,ANXA6,BTG1,MARCKS,NEDD4L,TJP2,FMNL3,SSRP1,GFAP,EPB41L1,API5,DDX24,PAX6,EZR,DPYSL2,CCT4,ILK,CCT2,MAP3K10,DNM2,YWHAE,MYH10,GPHN,MLF1,ADD1,HDAC3,MTOR,TRIO,CTBP1,BCL2,EGR1,SYT1,KIF5C,TRAF6,BAIAP2,SPG20,YWHAH,RPL23,ARF4,TNIP1,ADAR,RPL14,G3BP2,FLII,PACSIN1,NGFR,HDLBP,CABIN1,CSK,CAPZA1,BAG1,DDB1,CAV1,CABLES1,PFKM,AP3D1,PTK2B,HMGB2,DIAPH1,DNAJB1,PRKRA,SNX27,APP,ARFGAP1,WDR6,LDHA,NACA,PTK6,FABP5,MAGED1,TGM2,STIP1,ZDHHC17,SRRT,MYO6,TPM2,YWHAZ,VPS39,MLLT4,TP53,DBN1,RASA1,EEF1A1,TAF4,USP14,PRKAA2,RAB3A,AASDHPPT,PIK3R1,RAP1B,CAPN2,CEP63,DYNC1I2,PPL,ARPC1A,GMDS,ADD3,HSPA8,PSMD8,DNM1L,TEKT1,USP21,CEP250,RBM19,TBCD,TCP1,AP1G1,HDAC2,CTH,FNBP1,BCAS4,MLF2,FNTA,ITPR1,NR3C1,SMG5,PPFIA3,STXBP1,CTNNB1,TYK2,MCM3AP,AKT1,GIT1,ATP6V0A1,TRIP10,TAF4B,CAPZB,HSPA4,HDAC1,PDE1B,HUWE1,CAMK2B,DNM1,HSPA9,HADHA,NUMA1,PPP1R13B,SEPT7,HTT,CAMK1D,DCTN1,GJA1,REST,SNCA,CDH13,ZFP36L2,UBQLN2,TUBG1,INPPL1,MAD1L1,TPR,APAF1,SUMO1,TRAF1,ADD2,UBQLN1,RAD51C,SORBS1,USP9X,CHD3,DLD,PSMA1,SIN3B,TSC2,FHOD3,XPC,EGFR,RAD23B,DUSP8,CBS,SPHK2,PGM1,TRAF3,NISCH,ARHGAP1,MAX,ACTB,CAPZA2,CYFIP2,USP7,NDRG2,YWHAB,CRNKL1,ACTR1B,GOT1,DLG4,TBP,CASP1,GSK3B,ARHGEF6,LANCL1,INPP5B,EFTUD2,PFN2,NUP62,BECN1,ACTN1,GCN1L1,GNAI2,CASP7,EWSR1,YBX1,PSPC1,RECQL5,CASK,SH3GL3,USP8,TMOD2,GSN,UCHL3,NCOR1,NXT2,UPF1,GSTP1,BAP1,VPS35,SQSTM1,TLN1,YWHAG,NUP153,SNAP25,CREBBP,ATM,WHSC1,ARL2,UGP2,CASP3,OGT,CASP8,RPS6,GAPDH,CORO1B,HMGB1PAFAH1B1,PARK2,GRB2,GPI,SEC24C,CASP2,PPP2R2A,NFKB1,AP2A2,NAPA,NSF,DYNC1H1,SRGAP1,MYO9B,EDC4,CASP6,PSMC2,MAPK1,EIF2AK2,PPP1CA,TUBB,Ube3a,EPB41L1,SRGAP2,EZR,DPYSL2,CCT4,ILK,CCT2,RPL7,DNM2,YWHAE,ADD1,MTOR,TRIO,BCL2,TRAF6,BAIAP2,USP19,ARHGAP18,RPL23,RPL15,RPL14,RPL13,G3BP2,NGFR,CSK,CAPZA1,BAG1,CAV1,CABLES1,PFKM,PTK2B,SNX27,APP,ARFGAP1,LDHA,PAICS,MYO6,TPM2,YWHAZ,MLLT4,TP53,RASA1,EEF1A1,RANBP2,CAMK2G,PRKAA2,AASDHPPT,PIK3R1,RAP1B,CEP63,DYNC1I2,HSPA8,PSMD8,DNM1L,CEP250,NUP98,AP1B1,TCP1,ALDOA,AP1G1,FNTA,NR3C1,SMG5,STXBP1,CTNNB1,TYK2,MCM3AP,AKT1,THY1,TRIP10,CAPZB,HSPA4,HDAC1,PDE1B,CAMK2B,NUMA1,HTT,RAB14,DCTN1,PPM1A,REST,SNCA,TUBG1,FABP3,PAH,CLTC,INPPL1,MAD1L1,APAF1,ANAPC1,SORBS1,NUP160,PSMA1,TSC2,CBS,SPHK2,PGM1,TRAF3,NISCH,ARHGAP1,CUL1,BUB3,ACTB,CAPZA2,NDRG2,YWHAB,ASNS,GOT1,MYL6,CASP1,GSK3B,AP2B1,RAC1,SEC23A,ARHGEF6,RAPGEF1,INPP5B,ACTN1,RPL6,GNAI2,CASP7,MAT2A,USP8,GSN,ARHGEF7,RPLP2,UPF1,GSTP1,VPS35,SQSTM1,TLN1,YWHAG,AP2A1,ARL2,UGP2,GSS,CASP3,OGT,CASP8,RPS6,GAPDH,PSMD3PAFAH1B1,MECP2,FLNB,PARK2,ELK1,SGK1,TFEB,GRB2,SP1,UBR4,HIP1,GPI,VPRBP,SEC24C,XRCC6,ZNF292,CASP2,SREBF2,SF3A3,NFKB1,SFMBT2,SIRT1,EDC4,SYMPK,CASP6,PSMC2,MAPK1,PPP1CA,NCOR2,SRRM2,MED15,Ube3a,BTG1,TJP2,SSRP1,API5,PAX6,BCL11B,SIN3A,CCT4,COX4I1,CCT2,NFYA,GTF3C5,DNM2,MLF1,ADD1,HDAC3,MTOR,CTBP1,BCL2,EGR1,TRAF6,BAIAP2,ZNF207,DUSP2,ASXL1,TNIP1,ADAR,TRRAP,BATF,FLII,PRPF8,SNRNP200,NGFR,HDLBP,CABIN1,BAG1,DDB1,CABLES1,RNGTT,PTK2B,HMGB2,DOT1L,CHD8,DNAJB1,DRD1,POU2AF1,SF3B3,KIAA0556,NACA,PTK6,STIP1,SRRT,MYO6,YWHAZ,MLLT4,SMARCA4,MAF,SRCAP,TP53,CREBL2,EEF1A1,RANBP2,MEF2D,TAF4,PRKAA2,PIK3R1,RBM5,EP400,DNAJC1,CAPN2,PPL,POLR3E,PSMD8,USP21,RBM19,NUP98,DDX5,TCP1,HDAC2,EZH1,FADS1,CTH,MLF2,NR3C1,SMG5,SUPT5H,CTNNB1,TYK2,MCM3AP,AKT1,ATP6V0A1,TAF4B,HSPA4,MED23,HDAC1,PDE1B,HUWE1,POU3F2,SBF1,NUMA1,PPP1R13B,SEPT7,SNW1,KAT2B,HTT,CAMK1D,PPM1A,REST,SNCA,ZFP36L2,UBQLN2,MAD1L1,TPR,APAF1,SUMO1,SF3B2,CPT2,UBQLN1,RAD51C,ANAPC1,SORBS1,CHD3,NUP160,PSMA1,SIN3B,PPIL2,TSC2,FHOD3,XPC,EGFR,RAD23B,USP1,DUSP8,CBS,MAX,BUB3,USP7,NDRG2,YWHAB,CRNKL1,MYCBP2,MYEF2,BMP2K,CBFA2T2,TP53INP1,GSK3B,ARNTL,LANCL1,EFTUD2,ZNF91,NUP62,ACTN1,GNAI2,EWSR1,YBX1,PSPC1,RECQL5,CASK,ZNF24,USP8,SUGP2,UCHL3,NCOR1,ZMYND8,DHX8,NXT2,GSTP1,BAP1,SQSTM1,NFYC,NUP153,CREBBP,ATM,WHSC1,ARL2,SMARCC2,CASP3,OGT,CASP8,RPS6,RNMT,GAPDH,NOP14,PPP1R16B,HIST1H2AC,HMGB1XRCC6,SF3A3,NFKB1,SIRT1,SYMPK,CASP6,PSMC2,MAPK1,PPP1CA,NCOR2,MED15,SSRP1,SIN3A,GTF3C5,HDAC3,EGR1,DUSP2,ADAR,PRPF8,SNRNP200,NGFR,DDB1,RNGTT,HMGB2,SF3B3,SRRT,MYO6,YWHAZ,TP53,CAMK2G,TAF4,PRKAA2,RBM5,POLR3E,PSMD8,RBM19,NUP98,HDAC2,NR3C1,SUPT5H,AKT1,TAF4B,MED23,HDAC1,CAMK2B,NUMA1,SNW1,KAT2B,TPR,SUMO1,SF3B2,RAD51C,ANAPC1,PSMA1,SIN3B,XPC,RAD23B,USP1,CUL1,TBP,EFTUD2,CASP7,YBX1,PSPC1,RECQL5,NCOR1,SQSTM1,NUP153,CREBBP,ATM,CASP3,RNMT,PSMD3,HMGB1PAFAH1B1,SP1,GPI,SEC24C,SF3A3,NFKB1,SIRT1,SYMPK,PSMC2,PPP1CA,NCOR2,SRRM2,API5,DDX24,PAX6,EZR,SIN3A,CCT4,CCT2,CTBP1,TRAF6,BAIAP2,RPL23,ZNF207,ADAR,TRRAP,FLII,SNRNP200,CABIN1,PTK2B,HMGB2,DNAJB1,KIAA0556,PTK6,MLLT4,TP53,MEF2D,TAF4,RBM5,POLR3E,PSMD8,RBM19,DDX5,TCP1,EZH1,ITPR1,NR3C1,SUPT5H,ATP6V0A1,TAF4B,HSPA4,HDAC1,PDE1B,HUWE1,HADHA,NUMA1,PPP1R13B,SEPT7,SNW1,HTT,REST,APAF1,SF3B2,CPT2,SORBS1,PSMA1,PPIL2,FHOD3,RAD23B,CBS,MAX,BUB3,NDRG2,YWHAB,MYEF2,BMP2K,GSK3B,EFTUD2,PSPC1,RECQL5,BAP1,NUP153,WHSC1,SMARCC2,CASP3,OGT,RPS6,RNMT,NOP14,HMGB1

FLNB,SGK1,GPI,AP2A2,SLC41A1,NSF,MICA,TNFRSF8,SYMPK,ATP5B,FEZ1,GRIN2A,MARCKS,RASD2,TJP2,EPB41L1,EZR,VAMP2,ILK,GNAZ,DNM2,MYH10,NCKAP1,GPHN,ZFYVE27,MBP,ADD1,SYT1,TRAF6,BAIAP2,ARF4,TNFSF13B,NGFR,HDLBP,RAB10,CNR1,CSK,CAV1,CACNA1E,PTK2B,DIAPH1,APP,DRD1,KIAA0556,PTK6,NEGR1,MAGED1,SLC2A3,TGM2,MYO6,MLLT4,RAB28,RASA1,CAMK2G,VAPA,USP14,RAB3A,PIK3R1,RAP1B,CAPN2,PPL,GRIN1,ADD3,HSPA8,TBCD,RAB11A,AGPAT3,TCP1,FNBP1,ITPR1,ADORA2A,STXBP1,CTNNB1,AKT1,ENTPD3,THY1,ATP6V0A1,TRIP10,SLC16A1,GNB1,CAMK2B,PPP1R13B,SEPT7,RAB14,GJA1,SNCA,CDH13,UBQLN2,CNTN1,CLTC,INPPL1,CLDN12,ADD2,SORBS1,TMPRSS5,EGFR,KCNN3,ABCC10,NISCH,ARHGAP1,ATP1A1,DLG4,SNAP91,GSK3B,AP2B1,RAC1,CD22,STX1A,ATP5A1,ACTN1,ATP1B1,GNAI2,EWSR1,CASK,USP8,WNT10A,GSTP1,TLN1,KCNC1,VDAC1,SNAP25,AP2A1,ENTPD1,CASP3,OGT,PPP1R16BPARK2,NDUFV1,SGK1,CASP2,NFKB1,SLC25A3,PSMC2,ATP5B,FEZ1,MAPK1,SLC25A4,DPYSL2,COX4I1,UQCRC2,YWHAE,MTOR,BCL2,SPG7,MRPS5,NDUFV2,BAG1,CAV1,LDHA,TGM2,YWHAZ,TRAP1,TOMM22,TP53,COX6C,PPL,RAB11A,ECH1,ATP5C1,STXBP1,ATP5F1,SUCLA2,SLC16A1,HSPA9,HADHA,NDUFS3,SLC25A11,VDAC3,CPT1B,CLTC,MAD1L1,CPT2,RAD51C,CHCHD4,DLD,SLC25A12,TRAF3,VDAC2,ATP5A1,GLOD4,NDUFS1,NDUFB10,UCHL3,NDUFA8,VDAC1,NDUFB8,SLC25A13,ARL2,ME2,CASP3,CASP8,NOP14,HSPA2PAFAH1B1,UBR4,HIP1,DYNC1H1,SYMPK,MAPK1,TUBB,EPB41L1,EZR,CCT4,DNM2,GPHN,ADD1,KIF5C,FLII,CAPZA1,PTK2B,DIAPH1,TPM2,CEP63,DYNC1I2,PPL,ARPC1A,ADD3,TEKT1,CEP250,TCP1,FNBP1,CTNNB1,TYK2,TRIP10,CAPZB,CAMK2B,DNM1,DCTN1,SNCA,TUBG1,INPPL1,ADD2,SORBS1,CHD3,FHOD3,ACTB,ACTR1B,NUP62,ACTN1,GNAI2,TMOD2,ARL2,PCLO

SEC16A,PARK2,GRB2,HIP1,SYN1,SEC24C,SREBF2,DYNC1H1,MAPK1,MED15,COG1,MTOR,ARF4,RAB10,CSK,CAV1,AP3D1,APP,ARFGAP1,ENTPD6,STIP1,ZDHHC17,GALNT2,MYO6,B4GALT6,SRCAP,DNM1L,AP1B1,TCP1,AP1G1,ATP6V0A1,TRIP10,CALU,HTT,RAB14,GJA1,INPPL1,APAF1,TSC2,EGFR,GCNT1,NDRG2,MYEF2,SEC23A,BECN1,MGAT1,ARL2

SP1,ZNF292,CASP2,SF3A3,SRGAP1,EIF2AK2,Ube3a,NEDD4L,TBC1D5,SRGAP2,BCL11B,EZR,RPL7,TRIO,BCL2,DNAJC21,EGR1,ARHGAP18,TBC1D22A,RPL15,ZNF207,ARF4,TNIP1,ADAR,RPL14,RPL13,G3BP2,MRPS5,CAV1,PRKRA,GSPT1,DBN1,RASA1,PIK3R1,RBM5,RAP1B,CAPN2,GMDS,HSPA8,NR3C1,HUWE1,RAB14,REST,GGA3,APAF1,GBF1,TSC2,EGFR,ARHGAP1,CRNKL1,CASP1,ARHGEF6,RAPGEF1,INPP5B,ZNF91,RPL6,EWSR1,ZNF24,USP8,SUGP2,ARHGEF7,RPLP2,UCHL3,NXT2,GSTP1,BAP1,NFYC,NUP153,ARL2,SMARCC2,RPS6


PAFAH1B1,FLNB,PARK2,SGK1,TFEB,GRB2,SP1,UBR4,HIP1,GPI,VPRBP,SEC24C,XRCC6,CASP2,UBE2K,SREBF2,NFKB1,NSF,DYNC1H1,SIRT1,MYO9B,EDC4,TNFRSF8,SYMPK,CASP6,PSMC2,FEZ1,MAPK1,PPP1CA,MED15,TUBB,ANXA6,BTG1,MARCKS,NEDD4L,TJP2,FMNL3,SSRP1,GFAP,EPB41L1,API5,DDX24,PAX6,EZR,DPYSL2,CCT4,ILK,CCT2,MAP3K10,DNM2,YWHAE,MYH10,GPHN,MLF1,ADD1,HDAC3,MTOR,TRIO,CTBP1,BCL2,EGR1,SYT1,KIF5C,TRAF6,BAIAP2,SPG20,YWHAH,RPL23,ARF4,TNIP1,ADAR,RPL14,G3BP2,FLII,PACSIN1,NGFR,HDLBP,CABIN1,CSK,CAPZA1,BAG1,DDB1,CAV1,CABLES1,PFKM,AP3D1,PTK2B,HMGB2,DIAPH1,DNAJB1,PRKRA,SNX27,APP,ARFGAP1,WDR6,LDHA,NACA,PTK6,FABP5,MAGED1,TGM2,STIP1,ZDHHC17,SRRT,MYO6,TPM2,YWHAZ,VPS39,MLLT4,TP53,DBN1,RASA1,EEF1A1,TAF4,USP14,PRKAA2,RAB3A,AASDHPPT,PIK3R1,RAP1B,CAPN2,CEP63,DYNC1I2,PPL,ARPC1A,GMDS,ADD3,HSPA8,PSMD8,DNM1L,TEKT1,USP21,CEP250,RBM19,TBCD,TCP1,AP1G1,HDAC2,CTH,FNBP1,BCAS4,MLF2,FNTA,ITPR1,NR3C1,SMG5,PPFIA3,STXBP1,CTNNB1,TYK2,MCM3AP,AKT1,GIT1,ATP6V0A1,TRIP10,TAF4B,CAPZB,HSPA4,HDAC1,PDE1B,HUWE1,CAMK2B,DNM1,HSPA9,HADHA,NUMA1,PPP1R13B,SEPT7,HTT,CAMK1D,DCTN1,GJA1,REST,SNCA,CDH13,ZFP36L2,UBQLN2,TUBG1,INPPL1,MAD1L1,TPR,APAF1,SUMO1,TRAF1,ADD2,UBQLN1,RAD51C,SORBS1,USP9X,CHD3,DLD,PSMA1,SIN3B,TSC2,FHOD3,XPC,EGFR,RAD23B,DUSP8,CBS,SPHK2,PGM1,TRAF3,NISCH,ARHGAP1,MAX,ACTB,CAPZA2,CYFIP2,USP7,NDRG2,YWHAB,CRNKL1,ACTR1B,GOT1,DLG4,TBP,CASP1,GSK3B,ARHGEF6,LANCL1,INPP5B,EFTUD2,PFN2,NUP62,BECN1,ACTN1,GCN1L1,GNAI2,CASP7,EWSR1,YBX1,PSPC1,RECQL5,CASK,SH3GL3,USP8,TMOD2,GSN,UCHL3,NCOR1,NXT2,UPF1,GSTP1,BAP1,VPS35,SQSTM1,TLN1,YWHAG,NUP153,SNAP25,CREBBP,ATM,WHSC1,ARL2,UGP2,CASP3,OGT,CASP8,RPS6,GAPDH,CORO1B,HMGB1PAFAH1B1,PARK2,GRB2,GPI,SEC24C,CASP2,PPP2R2A,NFKB1,AP2A2,NAPA,NSF,DYNC1H1,SRGAP1,MYO9B,EDC4,CASP6,PSMC2,MAPK1,EIF2AK2,PPP1CA,TUBB,Ube3a,EPB41L1,SRGAP2,EZR,DPYSL2,CCT4,ILK,CCT2,RPL7,DNM2,YWHAE,ADD1,MTOR,TRIO,BCL2,TRAF6,BAIAP2,USP19,ARHGAP18,RPL23,RPL15,RPL14,RPL13,G3BP2,NGFR,CSK,CAPZA1,BAG1,CAV1,CABLES1,PFKM,PTK2B,SNX27,APP,ARFGAP1,LDHA,PAICS,MYO6,TPM2,YWHAZ,MLLT4,TP53,RASA1,EEF1A1,RANBP2,CAMK2G,PRKAA2,AASDHPPT,PIK3R1,RAP1B,CEP63,DYNC1I2,HSPA8,PSMD8,DNM1L,CEP250,NUP98,AP1B1,TCP1,ALDOA,AP1G1,FNTA,NR3C1,SMG5,STXBP1,CTNNB1,TYK2,MCM3AP,AKT1,THY1,TRIP10,CAPZB,HSPA4,HDAC1,PDE1B,CAMK2B,NUMA1,HTT,RAB14,DCTN1,PPM1A,REST,SNCA,TUBG1,FABP3,PAH,CLTC,INPPL1,MAD1L1,APAF1,ANAPC1,SORBS1,NUP160,PSMA1,TSC2,CBS,SPHK2,PGM1,TRAF3,NISCH,ARHGAP1,CUL1,BUB3,ACTB,CAPZA2,NDRG2,YWHAB,ASNS,GOT1,MYL6,CASP1,GSK3B,AP2B1,RAC1,SEC23A,ARHGEF6,RAPGEF1,INPP5B,ACTN1,RPL6,GNAI2,CASP7,MAT2A,USP8,GSN,ARHGEF7,RPLP2,UPF1,GSTP1,VPS35,SQSTM1,TLN1,YWHAG,AP2A1,ARL2,UGP2,GSS,CASP3,OGT,CASP8,RPS6,GAPDH,PSMD3PAFAH1B1,MECP2,FLNB,PARK2,ELK1,SGK1,TFEB,GRB2,SP1,UBR4,HIP1,GPI,VPRBP,SEC24C,XRCC6,ZNF292,CASP2,SREBF2,SF3A3,NFKB1,SFMBT2,SIRT1,EDC4,SYMPK,CASP6,PSMC2,MAPK1,PPP1CA,NCOR2,SRRM2,MED15,Ube3a,BTG1,TJP2,SSRP1,API5,PAX6,BCL11B,SIN3A,CCT4,COX4I1,CCT2,NFYA,GTF3C5,DNM2,MLF1,ADD1,HDAC3,MTOR,CTBP1,BCL2,EGR1,TRAF6,BAIAP2,ZNF207,DUSP2,ASXL1,TNIP1,ADAR,TRRAP,BATF,FLII,PRPF8,SNRNP200,NGFR,HDLBP,CABIN1,BAG1,DDB1,CABLES1,RNGTT,PTK2B,HMGB2,DOT1L,CHD8,DNAJB1,DRD1,POU2AF1,SF3B3,KIAA0556,NACA,PTK6,STIP1,SRRT,MYO6,YWHAZ,MLLT4,SMARCA4,MAF,SRCAP,TP53,CREBL2,EEF1A1,RANBP2,MEF2D,TAF4,PRKAA2,PIK3R1,RBM5,EP400,DNAJC1,CAPN2,PPL,POLR3E,PSMD8,USP21,RBM19,NUP98,DDX5,TCP1,HDAC2,EZH1,FADS1,CTH,MLF2,NR3C1,SMG5,SUPT5H,CTNNB1,TYK2,MCM3AP,AKT1,ATP6V0A1,TAF4B,HSPA4,MED23,HDAC1,PDE1B,HUWE1,POU3F2,SBF1,NUMA1,PPP1R13B,SEPT7,SNW1,KAT2B,HTT,CAMK1D,PPM1A,REST,SNCA,ZFP36L2,UBQLN2,MAD1L1,TPR,APAF1,SUMO1,SF3B2,CPT2,UBQLN1,RAD51C,ANAPC1,SORBS1,CHD3,NUP160,PSMA1,SIN3B,PPIL2,TSC2,FHOD3,XPC,EGFR,RAD23B,USP1,DUSP8,CBS,MAX,BUB3,USP7,NDRG2,YWHAB,CRNKL1,MYCBP2,MYEF2,BMP2K,CBFA2T2,TP53INP1,GSK3B,ARNTL,LANCL1,EFTUD2,ZNF91,NUP62,ACTN1,GNAI2,EWSR1,YBX1,PSPC1,RECQL5,CASK,ZNF24,USP8,SUGP2,UCHL3,NCOR1,ZMYND8,DHX8,NXT2,GSTP1,BAP1,SQSTM1,NFYC,NUP153,CREBBP,ATM,WHSC1,ARL2,SMARCC2,CASP3,OGT,CASP8,RPS6,RNMT,GAPDH,NOP14,PPP1R16B,HIST1H2AC,HMGB1XRCC6,SF3A3,NFKB1,SIRT1,SYMPK,CASP6,PSMC2,MAPK1,PPP1CA,NCOR2,MED15,SSRP1,SIN3A,GTF3C5,HDAC3,EGR1,DUSP2,ADAR,PRPF8,SNRNP200,NGFR,DDB1,RNGTT,HMGB2,SF3B3,SRRT,MYO6,YWHAZ,TP53,CAMK2G,TAF4,PRKAA2,RBM5,POLR3E,PSMD8,RBM19,NUP98,HDAC2,NR3C1,SUPT5H,AKT1,TAF4B,MED23,HDAC1,CAMK2B,NUMA1,SNW1,KAT2B,TPR,SUMO1,SF3B2,RAD51C,ANAPC1,PSMA1,SIN3B,XPC,RAD23B,USP1,CUL1,TBP,EFTUD2,CASP7,YBX1,PSPC1,RECQL5,NCOR1,SQSTM1,NUP153,CREBBP,ATM,CASP3,RNMT,PSMD3,HMGB1PAFAH1B1,SP1,GPI,SEC24C,SF3A3,NFKB1,SIRT1,SYMPK,PSMC2,PPP1CA,NCOR2,SRRM2,API5,DDX24,PAX6,EZR,SIN3A,CCT4,CCT2,CTBP1,TRAF6,BAIAP2,RPL23,ZNF207,ADAR,TRRAP,FLII,SNRNP200,CABIN1,PTK2B,HMGB2,DNAJB1,KIAA0556,PTK6,MLLT4,TP53,MEF2D,TAF4,RBM5,POLR3E,PSMD8,RBM19,DDX5,TCP1,EZH1,ITPR1,NR3C1,SUPT5H,ATP6V0A1,TAF4B,HSPA4,HDAC1,PDE1B,HUWE1,HADHA,NUMA1,PPP1R13B,SEPT7,SNW1,HTT,REST,APAF1,SF3B2,CPT2,SORBS1,PSMA1,PPIL2,FHOD3,RAD23B,CBS,MAX,BUB3,NDRG2,YWHAB,MYEF2,BMP2K,GSK3B,EFTUD2,PSPC1,RECQL5,BAP1,NUP153,WHSC1,SMARCC2,CASP3,OGT,RPS6,RNMT,NOP14,HMGB1

FLNB,SGK1,GPI,AP2A2,SLC41A1,NSF,MICA,TNFRSF8,SYMPK,ATP5B,FEZ1,GRIN2A,MARCKS,RASD2,TJP2,EPB41L1,EZR,VAMP2,ILK,GNAZ,DNM2,MYH10,NCKAP1,GPHN,ZFYVE27,MBP,ADD1,SYT1,TRAF6,BAIAP2,ARF4,TNFSF13B,NGFR,HDLBP,RAB10,CNR1,CSK,CAV1,CACNA1E,PTK2B,DIAPH1,APP,DRD1,KIAA0556,PTK6,NEGR1,MAGED1,SLC2A3,TGM2,MYO6,MLLT4,RAB28,RASA1,CAMK2G,VAPA,USP14,RAB3A,PIK3R1,RAP1B,CAPN2,PPL,GRIN1,ADD3,HSPA8,TBCD,RAB11A,AGPAT3,TCP1,FNBP1,ITPR1,ADORA2A,STXBP1,CTNNB1,AKT1,ENTPD3,THY1,ATP6V0A1,TRIP10,SLC16A1,GNB1,CAMK2B,PPP1R13B,SEPT7,RAB14,GJA1,SNCA,CDH13,UBQLN2,CNTN1,CLTC,INPPL1,CLDN12,ADD2,SORBS1,TMPRSS5,EGFR,KCNN3,ABCC10,NISCH,ARHGAP1,ATP1A1,DLG4,SNAP91,GSK3B,AP2B1,RAC1,CD22,STX1A,ATP5A1,ACTN1,ATP1B1,GNAI2,EWSR1,CASK,USP8,WNT10A,GSTP1,TLN1,KCNC1,VDAC1,SNAP25,AP2A1,ENTPD1,CASP3,OGT,PPP1R16BPARK2,NDUFV1,SGK1,CASP2,NFKB1,SLC25A3,PSMC2,ATP5B,FEZ1,MAPK1,SLC25A4,DPYSL2,COX4I1,UQCRC2,YWHAE,MTOR,BCL2,SPG7,MRPS5,NDUFV2,BAG1,CAV1,LDHA,TGM2,YWHAZ,TRAP1,TOMM22,TP53,COX6C,PPL,RAB11A,ECH1,ATP5C1,STXBP1,ATP5F1,SUCLA2,SLC16A1,HSPA9,HADHA,NDUFS3,SLC25A11,VDAC3,CPT1B,CLTC,MAD1L1,CPT2,RAD51C,CHCHD4,DLD,SLC25A12,TRAF3,VDAC2,ATP5A1,GLOD4,NDUFS1,NDUFB10,UCHL3,NDUFA8,VDAC1,NDUFB8,SLC25A13,ARL2,ME2,CASP3,CASP8,NOP14,HSPA2

SP1,ZNF292,CASP2,SF3A3,SRGAP1,EIF2AK2,Ube3a,NEDD4L,TBC1D5,SRGAP2,BCL11B,EZR,RPL7,TRIO,BCL2,DNAJC21,EGR1,ARHGAP18,TBC1D22A,RPL15,ZNF207,ARF4,TNIP1,ADAR,RPL14,RPL13,G3BP2,MRPS5,CAV1,PRKRA,GSPT1,DBN1,RASA1,PIK3R1,RBM5,RAP1B,CAPN2,GMDS,HSPA8,NR3C1,HUWE1,RAB14,REST,GGA3,APAF1,GBF1,TSC2,EGFR,ARHGAP1,CRNKL1,CASP1,ARHGEF6,RAPGEF1,INPP5B,ZNF91,RPL6,EWSR1,ZNF24,USP8,SUGP2,ARHGEF7,RPLP2,UCHL3,NXT2,GSTP1,BAP1,NFYC,NUP153,ARL2,SMARCC2,RPS6


PAFAH1B1,FLNB,PARK2,SGK1,TFEB,GRB2,SP1,UBR4,HIP1,GPI,VPRBP,SEC24C,XRCC6,CASP2,UBE2K,SREBF2,NFKB1,NSF,DYNC1H1,SIRT1,MYO9B,EDC4,TNFRSF8,SYMPK,CASP6,PSMC2,FEZ1,MAPK1,PPP1CA,MED15,TUBB,ANXA6,BTG1,MARCKS,NEDD4L,TJP2,FMNL3,SSRP1,GFAP,EPB41L1,API5,DDX24,PAX6,EZR,DPYSL2,CCT4,ILK,CCT2,MAP3K10,DNM2,YWHAE,MYH10,GPHN,MLF1,ADD1,HDAC3,MTOR,TRIO,CTBP1,BCL2,EGR1,SYT1,KIF5C,TRAF6,BAIAP2,SPG20,YWHAH,RPL23,ARF4,TNIP1,ADAR,RPL14,G3BP2,FLII,PACSIN1,NGFR,HDLBP,CABIN1,CSK,CAPZA1,BAG1,DDB1,CAV1,CABLES1,PFKM,AP3D1,PTK2B,HMGB2,DIAPH1,DNAJB1,PRKRA,SNX27,APP,ARFGAP1,WDR6,LDHA,NACA,PTK6,FABP5,MAGED1,TGM2,STIP1,ZDHHC17,SRRT,MYO6,TPM2,YWHAZ,VPS39,MLLT4,TP53,DBN1,RASA1,EEF1A1,TAF4,USP14,PRKAA2,RAB3A,AASDHPPT,PIK3R1,RAP1B,CAPN2,CEP63,DYNC1I2,PPL,ARPC1A,GMDS,ADD3,HSPA8,PSMD8,DNM1L,TEKT1,USP21,CEP250,RBM19,TBCD,TCP1,AP1G1,HDAC2,CTH,FNBP1,BCAS4,MLF2,FNTA,ITPR1,NR3C1,SMG5,PPFIA3,STXBP1,CTNNB1,TYK2,MCM3AP,AKT1,GIT1,ATP6V0A1,TRIP10,TAF4B,CAPZB,HSPA4,HDAC1,PDE1B,HUWE1,CAMK2B,DNM1,HSPA9,HADHA,NUMA1,PPP1R13B,SEPT7,HTT,CAMK1D,DCTN1,GJA1,REST,SNCA,CDH13,ZFP36L2,UBQLN2,TUBG1,INPPL1,MAD1L1,TPR,APAF1,SUMO1,TRAF1,ADD2,UBQLN1,RAD51C,SORBS1,USP9X,CHD3,DLD,PSMA1,SIN3B,TSC2,FHOD3,XPC,EGFR,RAD23B,DUSP8,CBS,SPHK2,PGM1,TRAF3,NISCH,ARHGAP1,MAX,ACTB,CAPZA2,CYFIP2,USP7,NDRG2,YWHAB,CRNKL1,ACTR1B,GOT1,DLG4,TBP,CASP1,GSK3B,ARHGEF6,LANCL1,INPP5B,EFTUD2,PFN2,NUP62,BECN1,ACTN1,GCN1L1,GNAI2,CASP7,EWSR1,YBX1,PSPC1,RECQL5,CASK,SH3GL3,USP8,TMOD2,GSN,UCHL3,NCOR1,NXT2,UPF1,GSTP1,BAP1,VPS35,SQSTM1,TLN1,YWHAG,NUP153,SNAP25,CREBBP,ATM,WHSC1,ARL2,UGP2,CASP3,OGT,CASP8,RPS6,GAPDH,CORO1B,HMGB1PAFAH1B1,PARK2,GRB2,GPI,SEC24C,CASP2,PPP2R2A,NFKB1,AP2A2,NAPA,NSF,DYNC1H1,SRGAP1,MYO9B,EDC4,CASP6,PSMC2,MAPK1,EIF2AK2,PPP1CA,TUBB,Ube3a,EPB41L1,SRGAP2,EZR,DPYSL2,CCT4,ILK,CCT2,RPL7,DNM2,YWHAE,ADD1,MTOR,TRIO,BCL2,TRAF6,BAIAP2,USP19,ARHGAP18,RPL23,RPL15,RPL14,RPL13,G3BP2,NGFR,CSK,CAPZA1,BAG1,CAV1,CABLES1,PFKM,PTK2B,SNX27,APP,ARFGAP1,LDHA,PAICS,MYO6,TPM2,YWHAZ,MLLT4,TP53,RASA1,EEF1A1,RANBP2,CAMK2G,PRKAA2,AASDHPPT,PIK3R1,RAP1B,CEP63,DYNC1I2,HSPA8,PSMD8,DNM1L,CEP250,NUP98,AP1B1,TCP1,ALDOA,AP1G1,FNTA,NR3C1,SMG5,STXBP1,CTNNB1,TYK2,MCM3AP,AKT1,THY1,TRIP10,CAPZB,HSPA4,HDAC1,PDE1B,CAMK2B,NUMA1,HTT,RAB14,DCTN1,PPM1A,REST,SNCA,TUBG1,FABP3,PAH,CLTC,INPPL1,MAD1L1,APAF1,ANAPC1,SORBS1,NUP160,PSMA1,TSC2,CBS,SPHK2,PGM1,TRAF3,NISCH,ARHGAP1,CUL1,BUB3,ACTB,CAPZA2,NDRG2,YWHAB,ASNS,GOT1,MYL6,CASP1,GSK3B,AP2B1,RAC1,SEC23A,ARHGEF6,RAPGEF1,INPP5B,ACTN1,RPL6,GNAI2,CASP7,MAT2A,USP8,GSN,ARHGEF7,RPLP2,UPF1,GSTP1,VPS35,SQSTM1,TLN1,YWHAG,AP2A1,ARL2,UGP2,GSS,CASP3,OGT,CASP8,RPS6,GAPDH,PSMD3PAFAH1B1,MECP2,FLNB,PARK2,ELK1,SGK1,TFEB,GRB2,SP1,UBR4,HIP1,GPI,VPRBP,SEC24C,XRCC6,ZNF292,CASP2,SREBF2,SF3A3,NFKB1,SFMBT2,SIRT1,EDC4,SYMPK,CASP6,PSMC2,MAPK1,PPP1CA,NCOR2,SRRM2,MED15,Ube3a,BTG1,TJP2,SSRP1,API5,PAX6,BCL11B,SIN3A,CCT4,COX4I1,CCT2,NFYA,GTF3C5,DNM2,MLF1,ADD1,HDAC3,MTOR,CTBP1,BCL2,EGR1,TRAF6,BAIAP2,ZNF207,DUSP2,ASXL1,TNIP1,ADAR,TRRAP,BATF,FLII,PRPF8,SNRNP200,NGFR,HDLBP,CABIN1,BAG1,DDB1,CABLES1,RNGTT,PTK2B,HMGB2,DOT1L,CHD8,DNAJB1,DRD1,POU2AF1,SF3B3,KIAA0556,NACA,PTK6,STIP1,SRRT,MYO6,YWHAZ,MLLT4,SMARCA4,MAF,SRCAP,TP53,CREBL2,EEF1A1,RANBP2,MEF2D,TAF4,PRKAA2,PIK3R1,RBM5,EP400,DNAJC1,CAPN2,PPL,POLR3E,PSMD8,USP21,RBM19,NUP98,DDX5,TCP1,HDAC2,EZH1,FADS1,CTH,MLF2,NR3C1,SMG5,SUPT5H,CTNNB1,TYK2,MCM3AP,AKT1,ATP6V0A1,TAF4B,HSPA4,MED23,HDAC1,PDE1B,HUWE1,POU3F2,SBF1,NUMA1,PPP1R13B,SEPT7,SNW1,KAT2B,HTT,CAMK1D,PPM1A,REST,SNCA,ZFP36L2,UBQLN2,MAD1L1,TPR,APAF1,SUMO1,SF3B2,CPT2,UBQLN1,RAD51C,ANAPC1,SORBS1,CHD3,NUP160,PSMA1,SIN3B,PPIL2,TSC2,FHOD3,XPC,EGFR,RAD23B,USP1,DUSP8,CBS,MAX,BUB3,USP7,NDRG2,YWHAB,CRNKL1,MYCBP2,MYEF2,BMP2K,CBFA2T2,TP53INP1,GSK3B,ARNTL,LANCL1,EFTUD2,ZNF91,NUP62,ACTN1,GNAI2,EWSR1,YBX1,PSPC1,RECQL5,CASK,ZNF24,USP8,SUGP2,UCHL3,NCOR1,ZMYND8,DHX8,NXT2,GSTP1,BAP1,SQSTM1,NFYC,NUP153,CREBBP,ATM,WHSC1,ARL2,SMARCC2,CASP3,OGT,CASP8,RPS6,RNMT,GAPDH,NOP14,PPP1R16B,HIST1H2AC,HMGB1

PAFAH1B1,SP1,GPI,SEC24C,SF3A3,NFKB1,SIRT1,SYMPK,PSMC2,PPP1CA,NCOR2,SRRM2,API5,DDX24,PAX6,EZR,SIN3A,CCT4,CCT2,CTBP1,TRAF6,BAIAP2,RPL23,ZNF207,ADAR,TRRAP,FLII,SNRNP200,CABIN1,PTK2B,HMGB2,DNAJB1,KIAA0556,PTK6,MLLT4,TP53,MEF2D,TAF4,RBM5,POLR3E,PSMD8,RBM19,DDX5,TCP1,EZH1,ITPR1,NR3C1,SUPT5H,ATP6V0A1,TAF4B,HSPA4,HDAC1,PDE1B,HUWE1,HADHA,NUMA1,PPP1R13B,SEPT7,SNW1,HTT,REST,APAF1,SF3B2,CPT2,SORBS1,PSMA1,PPIL2,FHOD3,RAD23B,CBS,MAX,BUB3,NDRG2,YWHAB,MYEF2,BMP2K,GSK3B,EFTUD2,PSPC1,RECQL5,BAP1,NUP153,WHSC1,SMARCC2,CASP3,OGT,RPS6,RNMT,NOP14,HMGB1

FLNB,SGK1,GPI,AP2A2,SLC41A1,NSF,MICA,TNFRSF8,SYMPK,ATP5B,FEZ1,GRIN2A,MARCKS,RASD2,TJP2,EPB41L1,EZR,VAMP2,ILK,GNAZ,DNM2,MYH10,NCKAP1,GPHN,ZFYVE27,MBP,ADD1,SYT1,TRAF6,BAIAP2,ARF4,TNFSF13B,NGFR,HDLBP,RAB10,CNR1,CSK,CAV1,CACNA1E,PTK2B,DIAPH1,APP,DRD1,KIAA0556,PTK6,NEGR1,MAGED1,SLC2A3,TGM2,MYO6,MLLT4,RAB28,RASA1,CAMK2G,VAPA,USP14,RAB3A,PIK3R1,RAP1B,CAPN2,PPL,GRIN1,ADD3,HSPA8,TBCD,RAB11A,AGPAT3,TCP1,FNBP1,ITPR1,ADORA2A,STXBP1,CTNNB1,AKT1,ENTPD3,THY1,ATP6V0A1,TRIP10,SLC16A1,GNB1,CAMK2B,PPP1R13B,SEPT7,RAB14,GJA1,SNCA,CDH13,UBQLN2,CNTN1,CLTC,INPPL1,CLDN12,ADD2,SORBS1,TMPRSS5,EGFR,KCNN3,ABCC10,NISCH,ARHGAP1,ATP1A1,DLG4,SNAP91,GSK3B,AP2B1,RAC1,CD22,STX1A,ATP5A1,ACTN1,ATP1B1,GNAI2,EWSR1,CASK,USP8,WNT10A,GSTP1,TLN1,KCNC1,VDAC1,SNAP25,AP2A1,ENTPD1,CASP3,OGT,PPP1R16B


PAFAH1B1,FLNB,PARK2,SGK1,TFEB,GRB2,SP1,UBR4,HIP1,GPI,VPRBP,SEC24C,XRCC6,CASP2,UBE2K,SREBF2,NFKB1,NSF,DYNC1H1,SIRT1,MYO9B,EDC4,TNFRSF8,SYMPK,CASP6,PSMC2,FEZ1,MAPK1,PPP1CA,MED15,TUBB,ANXA6,BTG1,MARCKS,NEDD4L,TJP2,FMNL3,SSRP1,GFAP,EPB41L1,API5,DDX24,PAX6,EZR,DPYSL2,CCT4,ILK,CCT2,MAP3K10,DNM2,YWHAE,MYH10,GPHN,MLF1,ADD1,HDAC3,MTOR,TRIO,CTBP1,BCL2,EGR1,SYT1,KIF5C,TRAF6,BAIAP2,SPG20,YWHAH,RPL23,ARF4,TNIP1,ADAR,RPL14,G3BP2,FLII,PACSIN1,NGFR,HDLBP,CABIN1,CSK,CAPZA1,BAG1,DDB1,CAV1,CABLES1,PFKM,AP3D1,PTK2B,HMGB2,DIAPH1,DNAJB1,PRKRA,SNX27,APP,ARFGAP1,WDR6,LDHA,NACA,PTK6,FABP5,MAGED1,TGM2,STIP1,ZDHHC17,SRRT,MYO6,TPM2,YWHAZ,VPS39,MLLT4,TP53,DBN1,RASA1,EEF1A1,TAF4,USP14,PRKAA2,RAB3A,AASDHPPT,PIK3R1,RAP1B,CAPN2,CEP63,DYNC1I2,PPL,ARPC1A,GMDS,ADD3,HSPA8,PSMD8,DNM1L,TEKT1,USP21,CEP250,RBM19,TBCD,TCP1,AP1G1,HDAC2,CTH,FNBP1,BCAS4,MLF2,FNTA,ITPR1,NR3C1,SMG5,PPFIA3,STXBP1,CTNNB1,TYK2,MCM3AP,AKT1,GIT1,ATP6V0A1,TRIP10,TAF4B,CAPZB,HSPA4,HDAC1,PDE1B,HUWE1,CAMK2B,DNM1,HSPA9,HADHA,NUMA1,PPP1R13B,SEPT7,HTT,CAMK1D,DCTN1,GJA1,REST,SNCA,CDH13,ZFP36L2,UBQLN2,TUBG1,INPPL1,MAD1L1,TPR,APAF1,SUMO1,TRAF1,ADD2,UBQLN1,RAD51C,SORBS1,USP9X,CHD3,DLD,PSMA1,SIN3B,TSC2,FHOD3,XPC,EGFR,RAD23B,DUSP8,CBS,SPHK2,PGM1,TRAF3,NISCH,ARHGAP1,MAX,ACTB,CAPZA2,CYFIP2,USP7,NDRG2,YWHAB,CRNKL1,ACTR1B,GOT1,DLG4,TBP,CASP1,GSK3B,ARHGEF6,LANCL1,INPP5B,EFTUD2,PFN2,NUP62,BECN1,ACTN1,GCN1L1,GNAI2,CASP7,EWSR1,YBX1,PSPC1,RECQL5,CASK,SH3GL3,USP8,TMOD2,GSN,UCHL3,NCOR1,NXT2,UPF1,GSTP1,BAP1,VPS35,SQSTM1,TLN1,YWHAG,NUP153,SNAP25,CREBBP,ATM,WHSC1,ARL2,UGP2,CASP3,OGT,CASP8,RPS6,GAPDH,CORO1B,HMGB1

PAFAH1B1,MECP2,FLNB,PARK2,ELK1,SGK1,TFEB,GRB2,SP1,UBR4,HIP1,GPI,VPRBP,SEC24C,XRCC6,ZNF292,CASP2,SREBF2,SF3A3,NFKB1,SFMBT2,SIRT1,EDC4,SYMPK,CASP6,PSMC2,MAPK1,PPP1CA,NCOR2,SRRM2,MED15,Ube3a,BTG1,TJP2,SSRP1,API5,PAX6,BCL11B,SIN3A,CCT4,COX4I1,CCT2,NFYA,GTF3C5,DNM2,MLF1,ADD1,HDAC3,MTOR,CTBP1,BCL2,EGR1,TRAF6,BAIAP2,ZNF207,DUSP2,ASXL1,TNIP1,ADAR,TRRAP,BATF,FLII,PRPF8,SNRNP200,NGFR,HDLBP,CABIN1,BAG1,DDB1,CABLES1,RNGTT,PTK2B,HMGB2,DOT1L,CHD8,DNAJB1,DRD1,POU2AF1,SF3B3,KIAA0556,NACA,PTK6,STIP1,SRRT,MYO6,YWHAZ,MLLT4,SMARCA4,MAF,SRCAP,TP53,CREBL2,EEF1A1,RANBP2,MEF2D,TAF4,PRKAA2,PIK3R1,RBM5,EP400,DNAJC1,CAPN2,PPL,POLR3E,PSMD8,USP21,RBM19,NUP98,DDX5,TCP1,HDAC2,EZH1,FADS1,CTH,MLF2,NR3C1,SMG5,SUPT5H,CTNNB1,TYK2,MCM3AP,AKT1,ATP6V0A1,TAF4B,HSPA4,MED23,HDAC1,PDE1B,HUWE1,POU3F2,SBF1,NUMA1,PPP1R13B,SEPT7,SNW1,KAT2B,HTT,CAMK1D,PPM1A,REST,SNCA,ZFP36L2,UBQLN2,MAD1L1,TPR,APAF1,SUMO1,SF3B2,CPT2,UBQLN1,RAD51C,ANAPC1,SORBS1,CHD3,NUP160,PSMA1,SIN3B,PPIL2,TSC2,FHOD3,XPC,EGFR,RAD23B,USP1,DUSP8,CBS,MAX,BUB3,USP7,NDRG2,YWHAB,CRNKL1,MYCBP2,MYEF2,BMP2K,CBFA2T2,TP53INP1,GSK3B,ARNTL,LANCL1,EFTUD2,ZNF91,NUP62,ACTN1,GNAI2,EWSR1,YBX1,PSPC1,RECQL5,CASK,ZNF24,USP8,SUGP2,UCHL3,NCOR1,ZMYND8,DHX8,NXT2,GSTP1,BAP1,SQSTM1,NFYC,NUP153,CREBBP,ATM,WHSC1,ARL2,SMARCC2,CASP3,OGT,CASP8,RPS6,RNMT,GAPDH,NOP14,PPP1R16B,HIST1H2AC,HMGB1

PAFAH1B1,FLNB,PARK2,SGK1,TFEB,GRB2,SP1,UBR4,HIP1,GPI,VPRBP,SEC24C,XRCC6,CASP2,UBE2K,SREBF2,NFKB1,NSF,DYNC1H1,SIRT1,MYO9B,EDC4,TNFRSF8,SYMPK,CASP6,PSMC2,FEZ1,MAPK1,PPP1CA,MED15,TUBB,ANXA6,BTG1,MARCKS,NEDD4L,TJP2,FMNL3,SSRP1,GFAP,EPB41L1,API5,DDX24,PAX6,EZR,DPYSL2,CCT4,ILK,CCT2,MAP3K10,DNM2,YWHAE,MYH10,GPHN,MLF1,ADD1,HDAC3,MTOR,TRIO,CTBP1,BCL2,EGR1,SYT1,KIF5C,TRAF6,BAIAP2,SPG20,YWHAH,RPL23,ARF4,TNIP1,ADAR,RPL14,G3BP2,FLII,PACSIN1,NGFR,HDLBP,CABIN1,CSK,CAPZA1,BAG1,DDB1,CAV1,CABLES1,PFKM,AP3D1,PTK2B,HMGB2,DIAPH1,DNAJB1,PRKRA,SNX27,APP,ARFGAP1,WDR6,LDHA,NACA,PTK6,FABP5,MAGED1,TGM2,STIP1,ZDHHC17,SRRT,MYO6,TPM2,YWHAZ,VPS39,MLLT4,TP53,DBN1,RASA1,EEF1A1,TAF4,USP14,PRKAA2,RAB3A,AASDHPPT,PIK3R1,RAP1B,CAPN2,CEP63,DYNC1I2,PPL,ARPC1A,GMDS,ADD3,HSPA8,PSMD8,DNM1L,TEKT1,USP21,CEP250,RBM19,TBCD,TCP1,AP1G1,HDAC2,CTH,FNBP1,BCAS4,MLF2,FNTA,ITPR1,NR3C1,SMG5,PPFIA3,STXBP1,CTNNB1,TYK2,MCM3AP,AKT1,GIT1,ATP6V0A1,TRIP10,TAF4B,CAPZB,HSPA4,HDAC1,PDE1B,HUWE1,CAMK2B,DNM1,HSPA9,HADHA,NUMA1,PPP1R13B,SEPT7,HTT,CAMK1D,DCTN1,GJA1,REST,SNCA,CDH13,ZFP36L2,UBQLN2,TUBG1,INPPL1,MAD1L1,TPR,APAF1,SUMO1,TRAF1,ADD2,UBQLN1,RAD51C,SORBS1,USP9X,CHD3,DLD,PSMA1,SIN3B,TSC2,FHOD3,XPC,EGFR,RAD23B,DUSP8,CBS,SPHK2,PGM1,TRAF3,NISCH,ARHGAP1,MAX,ACTB,CAPZA2,CYFIP2,USP7,NDRG2,YWHAB,CRNKL1,ACTR1B,GOT1,DLG4,TBP,CASP1,GSK3B,ARHGEF6,LANCL1,INPP5B,EFTUD2,PFN2,NUP62,BECN1,ACTN1,GCN1L1,GNAI2,CASP7,EWSR1,YBX1,PSPC1,RECQL5,CASK,SH3GL3,USP8,TMOD2,GSN,UCHL3,NCOR1,NXT2,UPF1,GSTP1,BAP1,VPS35,SQSTM1,TLN1,YWHAG,NUP153,SNAP25,CREBBP,ATM,WHSC1,ARL2,UGP2,CASP3,OGT,CASP8,RPS6,GAPDH,CORO1B,HMGB1

Supplementary Table S8A: HD associated genes with TVSHD associated genes Association TVSGRIN1 Caudate down, HDsi 4.5ADORA2A /A2AR Caudate down, AAO 4HDAC1 Functinally related and o 4HTT AO, Co-expressGenefrie 4ITPR1 Caudate down HTT, interac 4MAP3K10 Caudate down HTT, interac 4ATM Functinally related and o 3.5CALM1 Caudate down HTT, interac 3.5CASP1 Caudate UP, HTT interac 3.5CAV1 Caudate UP, HTT interac 3.5DLD Caudate down HTT, interac 3.5HSPA4 Hdsi, HTT interacting prot 3.5SIRT1 Caudate UP, HDsi 3.5SP1 Caudate UP, HTT interac 3.5TGM2 HTT interacting proteins 3.5TP53 Caudate UP, HTT interac 3.5ZDHHC17 HTT interacting proteins 3.5ACTB Caudate down HTT, interac 3ADD1 Caudate UP, Co-expressdb 3AKT1 HTT interacting proteins 3AP1B1 Co-expressdb, HTT interact 3AP1G1 Caudate down HTT, interac 3AP2A2 Caudate down, Co-expressd 3APAF1 Functinally related and o 3API5 Caudate down HTT, interac 3ARF4 Caudate down, HDsi 3ASPH Caudate UP, HTT interac 3ATP1A1 Caudate down HTT, interac 3ATP5A1 Caudate down, Hdsi, HTT i 3ATP5B Caudate down HTT, interac 3BAG1 HTT interacting proteins 3BECN1 HTT interacting proteins 3BMP2K Caudate UP, HTT interac 3CACNA2D1 Caudate down HTT, interac 3CAPN2 Caudate UP, HDsi 3CASP2 Caudate UP, HTT interac 3CASP3 Caudate UP, Hdsi, HTT int 3CASP6 Caudate UP, HTT interac 3CASP7 Caudate UP, HTT interac 3CCT2 Caudate down HTT, interac 3CCT4 Hdsi, HTT interacting prot 3

CDH13 HTT interacting proteins 3CLTC Caudate down HTT, interac 3CNR1 3 3COX6C Caudate down HTT, interac 3CREBBP Caudate UP, Co-expressdb 3CRNKL1 Caudate down, HDsi 3CTNNB1 Caudate UP, HTT interac 3CTSD Caudate UP, HDsi 3CUL1 Caudate UP, HDsi 3CUL2 Caudate down, Hdsi, HTT i 3DHX8 Co-expressdb, HDsi 3DLG4 Caudate down HTT, interac 3DNAJB1 Hdsi, HTT interacting prot 3DNAJC21 HTT interacting proteins 3DNM1 Caudate down HTT, interac 3DNM1L Caudate down HTT, interac 3DNM2 Caudate UP, Co-expressdb 3DRD1 Functinally related and o 3DYNC1H1 Co-expressdb, HTT interact 3DYNC1I2 HTT interacting proteins 3EFTUD2 Co-expressdb, HDsi 3FNTA Caudate UP, HDsi 3GAPDH Hdsi, HTT interacting prot 3GBF1 Caudate down, Co-express 3GNB1 Caudate down HTT, interac 3GPI Caudate down, Hdsi, HTT i 3GPM6A Caudate down HTT, interac 3GSK3B Caudate down, HDsi 3GSPT1 Caudate down HTT, interac 3HIP1 Caudate UP, HTT interac 3HMGB1 Caudate UP, HTT interac 3HMGB2 Caudate UP, HTT interac 3HSPA8 HTT interacting proteins 3HSPA9 Hdsi, HTT interacting prot 3HYPK Caudate UP, HTT interac 3MED23 HTT interacting proteins 3MLF1 HTT interacting proteins 3MLF2 Caudate down HTT, interac 3MLLT4 Caudate UP, HTT interac 3MYH10 Caudate down HTT, interac 3NAPA Caudate down HTT, interac 3NCOR1 HTT interacting proteins 3NDUFB10 Caudate down HTT, interac 3

NDUFV1 HTT interacting proteins 3NEGR1 Caudate down HTT, interac 3NSF Caudate down HTT, interac 3PACSIN1 Caudate down HTT, interac 3PARK2 Caudate down HTT, interac 3PDE1B Caudate down, HDsi 3PFN2 Caudate down HTT, interac 3POLR2A Co-expressdb, HDsi 3PRPF8 Co-expressGenefriends, Co 3PSMA1 Caudate down, HDsi 3

HTT interacting proteins 3RAB11A Caudate down, HDsi 3RASD2 Caudate down HTT, interac 3RPL13 Caudate UP, HDsi 3RPL14 Caudate down, HDsi 3RPL15 Caudate down HTT, interac 3RPL23 Caudate UP, HDsi 3RPL6 Hdsi, HTT interacting prot 3RPL7 Hdsi, HTT interacting prot 3SEPTIN7 HTT interacting proteins 3SF3A3 Caudate UP, Hdsi, HTT int 3SF3B3 Caudate down, Co-expres 3SH3GL3 HTT interacting proteins 3SIN3A Hdsi, HTT interacting prot 3SNAP25 Caudate down, Hdsi, HTT i 3SNAP91 Caudate down HTT, interac 3SNRNP200 Co-expressGenefriends, Co 3SNW1 Caudate UP, HDsi 3SPHK2 Caudate UP, HDsi 3STX1A Caudate down, Hdsi, HTT i 3STXBP1 Caudate down HTT, interac 3SUPT5H Co-expressdb, Hdsi, HTT 3TAF4 Caudate UP, HTT interac 3TAF4B Caudate down, HDsi 3TCP1 Caudate down HTT, interac 3TFEB Caudate UP, Co-expressGen 3TRIO Caudate down HTT, interac 3TUBB Caudate down HTT, interac 3UBA1 Co-expressdb, HDsi 3UBE2D2 Caudate down, HDsi 3UBE2H Caudate UP, HDsi 3UBE2K Hdsi, HTT interacting prot 3UBQLN1 HTT interacting proteins 3

PSMC2


UCHL3 Caudate down, HDsi 3USP9X HTT interacting proteins 3VDAC1 Caudate down HTT, interac 3VDAC2 HTT interacting proteins 3VDAC3 Caudate down HTT, interac 3YWHAB Caudate down HTT, interac 3YWHAE Caudate down, Hdsi, HTT i 3YWHAZ Caudate down, Hdsi, HTT i 3ZMYND8 HTT interacting proteins 3CASP8 HTT interacting proteins 2.5DCTN1 Caudate down, Co-expressd 2.5GRIN2A AO, Caudate down, HDsi 2.5HSPA2 Caudate UP, HTT interac 2.5MAPK1 Caudate down, HDsi 2.5PIK3R1 Caudate UP, HTT interac 2.5SYN1 Caudate down HTT, interac 2.5ACTN1 Caudate down HTT, interac 2AP2A1 Caudate down HTT, interac 2ATP6V0A1 Caudate down, Co-express 2BCL2 Caudate UP, Co-expressGen 2CBS Caudate UP, HTT interac 2DBN1 Caudate down HTT, interac 2NFKB1 Co-expressGenefriends, H 2PPP1R3D Caudate UP, HDsi 2SLC25A4 Caudate down, Hdsi, HTT i 2SLC2A3/GLUT3 Caudate down, HDsi 2YWHAH Caudate down HTT, interac 2HDAC2 Caudate down, HDsi 1HDAC3 Functinally related and o 1PPP1CA Caudate down HTT, interac 1B4GALT6 Caudate down, Co-expressG 0

Supplementary Table S8B: HD associated genes that are konown targets of FDA approved drugsGene Other name Description of geneADORA2A /A2AR ADORA2, RDC8 Adenosine A2a receptorATP1A1 ATPase, Na+/K+ transporBCL2 Bcl-2, PPP1R50 B-cell CLL/lymphoma 2CACNA2D1 CACNA2, CACNL2A, LCalcium channel, voltageCNR1 CANN6, CB-R, CB1, CCannabinoid receptor 1 (CPT2 CPT1, CPTASE Carnitine palmitoyltransDRD1 Dopamine receptor D1EGFR ERBB, ERBB1 Epidermal growth factor FADS1 D5D, FADS6, FADSD5,Fatty acid desaturase 1GRIN1 GluN1, NMDAR1 Glutamate receptor, ionotGRIN2A GluN2A, NMDAR2A Glutamate receptor, ionoGSS Glutathione synthetaseHDAC1 GON-10, HD1, RPD3L1Histone deacetylase 1HDAC2 RPD3, YAF1 Histone deacetylase 2HDAC3 HD3, RPD3, RPD3-2 Histone deacetylase 3HMGCR 3-hydroxy-3-methylglutaKCNC1 Kv3.1 Potassium voltage-gatedMAPK1 ERK, ERK2, MAPK2, pMitogen-activated proteiMTOR FLJ44809, FRAP, FRAPMechanistic target of raNFKB1 KBF1, NF-kappaB, NF-kNuclear factor of kappa NR3C1 GR, GRL Nuclear receptor subfamiPAH PH Phenylalanine hydroxylaSLC25A4 ANT1, PEO2, PEO3, T1Solute carrier family 25 SNAP25 bA416N4.2, dJ1068F16.Synaptosomal-associatedTNFRSF8 CD30, D1S166E, KI-1 Tumor necrosis factor rTUBB M40, MGC16435, OK/SWTubulin, beta class ITUBG1 TUBG, TUBGCP1 Tubulin, gamma 1VAMP2 SYB2, VAMP-2 Vesicle-associated membPRKAA1 AMPKa1 Protein kinase, AMP-activa

Supplementary Table S8B: HD associated genes that are konown targets of FDA approved drugsHD association Chromosome Localized Expression in tissuesCaudate down, AAO 22 Tissue enhancedCaudate down HTT, interac 1 Expressed in allCaudate UP, Co-expressGen 18 Expressed in allCaudate down HTT, interac 7 MixedAO, Caudate down 6 Tissue enhancedCaudate UP, HDsi 1 Nucleus but not nucleoliExpressed in allFunctinally related and o 5 Tissue enhancedCaudate UP, HTT interac 7 Plasma membrane, CytoTissue enhancedCaudate UP, HDsi 11 Expressed in allCaudate down, HDsi 9 Tissue enrichedAO, Caudate down, HDsi 16 Tissue enhancedCaudate down, HDsi 20 Nucleoli, Cytoplasm Expressed in allFunctinally related and o 1 Nucleus but not nucleoliExpressed in allCaudate down, HDsi 6 Nucleus Expressed in allFunctinally related and o 5 Nucleus but not nucleoliExpressed in allCaudate down, HDsi 5 Expressed in allCaudate down, HDsi 11 Tissue enrichedCaudate down, HDsi 22 Nucleus but not nucleoliExpressed in allCo-expressdb, HTT interact 1 Expressed in allCo-expressGenefriends, H 4 Nucleus but not nucleoliExpressed in allCaudate UP, HDsi 5 Nucleus but not nucleol Expressed in allCaudate UP, HDsi 12 Cytoplasm, CytoskeletonTissue enhancedCaudate down, Hdsi, HTT i 4 Group enrichedCaudate down, Hdsi, HTT i 20 Cytoplasm, Golgi apparatTissue enrichedCaudate down, Co-expressG 1 MixedCaudate down HTT, interac 6 Expressed in allHdsi, HTT interacting prot 17 Expressed in allCaudate down HTT, interac 17 Expressed in allFunctinally related but n 5 Nucleus Expressed in all

No of tissues Enhanced/enriched/groupStatus of drugs8 brain FDA approved small molecules/Biotech

32 FDA approved small molecules/Biotech32 FDA approved small molecules/Biotech30 FDA approved small molecules/Biotech20 brain FDA approved small molecules/Biotech32 FDA approved small molecules/Biotech

3 brain FDA approved small molecules/Biotech31 placenta FDA approved small molecules/Biotech32 FDA approved small molecules/Biotech

8 brain FDA approved small molecules/Biotech6 brain FDA approved small molecules/Biotech

32 FDA approved small molecules/Biotech32 FDA approved small molecules/Biotech32 FDA approved small molecules/Biotech32 FDA approved small molecules/Biotech32 FDA approved small molecules/Biotech

2 brain FDA approved small molecules/Biotech32 FDA approved small molecules/Biotech32 FDA approved small molecules/Biotech32 FDA approved small molecules/Biotech32 FDA approved small molecules/Biotech

8 kidney, liver FDA approved small molecules/Biotech32 heart muscle,skeletal musFDA approved small molecules/Biotech20 brain FDA approved small molecules/Biotech10 FDA approved small molecules/Biotech32 FDA approved small molecules/Biotech32 FDA approved small molecules/Biotech32 FDA approved small molecules/Biotech32 FDA approved small molecules/Biotech

Supplementary Table S8C: HD associated genes that are potenial targets Symbol Other symbolADAR ADAR1, G1P1, IFI4ALDOAAPP AD1ASNSATM ATA, ATC, ATD, ATDCATP2A2 ATP2B, DAR, SERCA2BAP1 hucep-6, KIAA0272, UCASK CAGH39, FGS4, LIN2,CALM1 CALML2, CAMI, DD13CASP10 MCH4CASP8 Casp-8, FLICE, MACHCTSD CLN10, CPSDCAV1 CAVCHD8 DUPLIN, HELSNF1, KCREBBP CBP, KAT3A, RSTS, RCTHCBS HIP4CTNS CTNS-LSB, PQLC4DLD DLDH, GCSL, LADDNM1L DRP1, DVLP, DYMPLEDNM2 CMTDI1, CMTDIB, DIENTPD1 ATPDase, CD39, NTPDaGPHN KIAA1385GPI AMF, NLKHADHA GBP, LCEH, LCHAD, ITPR1 Insp3r1, IP3R1, SCA15INPPL1 SHIP2LDHANDUFS1 CI-75kNDUFV1 CI-51KNUP98 NUP96PPIB CYPB, OI9PFKM PFK-1, PFKXPGM1PTK2B CADTK, CAKB, FAK2,POMT2 LGMD2NSNRNP200 ASCC3L1, BRR2, HELISLC16A1 MCT, MCT1SLC25A12 AralarSLC25A13 ARALAR2, CITRIN, CSLC25A3 PHC

SPG7 CAR, CMAR, SPG5CSUCLA2SYPSTX1A HPC-1, p35-1, STX1SNCA alpha-synuclein, NACPTMPRSS5 MGC141886, MGC1480TP53 LFS1, p53TYK2 JTK1UQCRC2 QCR2, UQCR2AKT1 AKT, PKB, PRKBA, RWHSC1 MMSET, NSD2

Supplementary Table S8C: HD associated genes that are potenial targets Description HD association Chromosome LocalizationAdenosine deaminase, RCo-expressGenefriends, Co 1 Nucleus, NucleoliAldolase A, fructose-bi Caudate down, Hdsi, HTT i 16 CytoplasmAmyloid beta (A4) precuCaudate down, HDsi 21 Golgi apparatus, VesicleAsparagine synthetase ( Caudate down, HDsi 7 CytoplasmAtaxia telangiectasia muFunctinally related and o 11ATPase, Ca++ transportinCaudate down HTT, interac 12BRCA1 associated proteiCaudate down, Co-expressd 3 Nucleus but not nucleoliCalcium/calmodulin-depCaudate UP, HDsi X Nucleus but not nucleoliCalmodulin 1 (phosphorylCaudate down HTT, interac 14 VesiclesCaspase 10, apoptosis-reHTT interacting proteins 2Caspase 8, apoptosis-relHTT interacting proteins 2 Cytoplasm, Nucleus but Cathepsin D Caudate UP, HDsi 11Caveolin 1, caveolae proCaudate UP, HTT interac 7 Golgi apparatusChromodomain helicase Co-expressGenefriends, Co 14 Nucleus but not nucleoliCREB binding protein Caudate UP, Co-expressdb 16 Nucleus but not nucleoliCystathionase (cystathi Caudate UP, HDsi 1 Nucleus, CytoplasmCystathionine-beta-synt Caudate UP, HTT interac 21 Nucleoli, VesiclesCystinosin, lysosomal cyCaudate UP, HDsi 17 Vesicles, Cytoskeleton (Dihydrolipoamide dehydCaudate down HTT, interac 7 MitochondriaDynamin 1-like Caudate down HTT, interac 12 Cytoplasm, VesiclesDynamin 2 Caudate UP, Co-expressdb 19 Cytoplasm, Golgi apparaEctonucleoside triphosp Caudate UP, Co-expressGe 10 Cytoskeleton (MicrotubuGephyrin Caudate down, Co-expressG 14Glucose-6-phosphate is Caudate down, Hdsi, HTT i 19 Plasma membrane, CytoplHydroxyacyl-CoA dehydroCaudate UP, HTT interac 2 MitochondriaInositol 1,4,5-trisphosphCaudate down HTT, interac 3 VesiclesInositol polyphosphate pCaudate UP, Co-expressdb 11 Cytoplasm, Golgi apparaLactate dehydrogenase Caudate down HTT, interac 11 Cytoplasm, VesiclesNADH dehydrogenase (ubCaudate down HTT, interac 2 MitochondriaNADH dehydrogenase (ubHTT interacting proteins 11Nucleoporin 98kDa Caudate UP, HDsi 11Peptidylprolyl isomeraseCaudate UP, HTT interac 15 Nucleus, Nucleoli, CytoPhosphofructokinase, muCaudate down, Hdsi, HTT i 12 Endoplasmic reticulumPhosphoglucomutase 1 Caudate UP, HDsi 1 Cytoskeleton (Actin filaProtein tyrosine kinase 2Caudate down, Co-expressG 8 Nucleus but not nucleoliProtein-O-mannosyltransCaudate UP, Co-expressdb 14Small nuclear ribonucle Co-expressGenefriends, Co 2 Nucleus but not nucleoliSolute carrier family 16 Caudate UP, HTT interac 1 Plasma membraneSolute carrier family 25 Caudate down HTT, interac 2 Nucleus but not nucleoliSolute carrier family 25 Caudate UP, HTT interac 7 MitochondriaSolute carrier family 25 Caudate down HTT, interac 12 Mitochondria

Spastic paraplegia 7 (pu Caudate UP, Co-expressdb 16Succinate-CoA ligase, ACaudate down HTT, interac 13 MitochondriaSynaptophysin Caudate down HTT, interac XSyntaxin 1A (brain) Caudate down, Hdsi, HTT i 7Synuclein, alpha (non AFunctinally related and o 4Transmembrane protease,Caudate UP, HDsi 11Tumor protein p53 Caudate UP, HTT interac 17 Nucleus but not nucleoliTyrosine kinase 2 Caudate UP, Co-expressGe 19 CytoplasmUbiquinol-cytochrome c rCaudate down HTT, interac 16 MitochondriaV-akt murine thymoma vHTT interacting proteins 14 Nucleus, Cytoskeleton (Wolf-Hirschhorn syndroCaudate down, Co-expressd 4 Nucleus

Expression status in tiss No of tissue Enhanced/enriche/groupStatus of drugsExpressed in all 32 Probable drugExpressed in all 32 Probable drugExpressed in all 32 Probable drugExpressed in all 32 Probable drugExpressed in all 32 Probable drugExpressed in all 32 Probable drugExpressed in all 32 Probable drugExpressed in all 32 Probable drugExpressed in all 32 Probable drugExpressed in all 32 Probable drugExpressed in all 32 Probable drugExpressed in all 32 Probable drugTissue enhanced 31 lung Probable drugExpressed in all 32 Probable drugExpressed in all 32 Probable drugTissue enhanced 31 liver Probable drugTissue enhanced 29 liver, pancreas Probable drugExpressed in all 32 Probable drugExpressed in all 32 Probable drugExpressed in all 32 Probable drugExpressed in all 32 Probable drugExpressed in all 32 Probable drugExpressed in all 32 Probable drugExpressed in all 32 Probable drugExpressed in all 32 Probable drugExpressed in all 32 Probable drugExpressed in all 32 Probable drugExpressed in all 32 Probable drugExpressed in all 32 Probable drugExpressed in all 32 Probable drugExpressed in all 32 Probable drugExpressed in all 32 Probable drugGroup enriched 32 heart muscle,skeletal musProbable drugExpressed in all 32 Probable drugExpressed in all 32 Probable drugExpressed in all 32 Probable drugExpressed in all 32 Probable drugExpressed in all 32 Probable drugExpressed in all 32 Probable drugExpressed in all 32 Probable drugExpressed in all 32 Probable drug

Expressed in all 32 Probable drugExpressed in all 32 Probable drugTissue enriched 20 brain Probable drugTissue enhanced 30 brain Probable drugTissue enhanced 31 bone marrow, brain Probable drugTissue enhanced 5 brain, salivary gland Probable drugExpressed in all 32 Probable drugExpressed in all 32 Probable drugExpressed in all 32 Probable drugExpressed in all 32 Probable drugExpressed in all 32 Probable drug

Supplementary Table S8D: HD associated genes that are potenial targets with TVS Gene symbol Other symbolITPR1 Insp3r1, IP3R1, SCA15, SCATM ATA, ATC, ATD, ATDC, TELCALM1 CALML2, CAMI, DD132, PCAV1 CAVDLD DLDH, GCSL, LADTP53 LFS1, p53SNRNP200 ASCC3L1, BRR2, HELIC2, KSTX1A HPC-1, p35-1, STX1GPI AMF, NLKNDUFV1 CI-51KCREBBP CBP, KAT3A, RSTS, RTSCTSD CLN10, CPSDDNM1L DRP1, DVLP, DYMPLE, HDYDNM2 CMTDI1, CMTDIB, DI-CMTBAKT1 AKT, PKB, PRKBA, RACCASP8 Casp-8, FLICE, MACH, MCCBS HIP4

Supplementary Table S8D: HD associated genes that are potenial targets with TVS Description HD association Chromosome LocalizationInositol 1,4,5-trisphosphatCaudate down HTT, interac 3 VesiclesAtaxia telangiectasia mutaFunctinally related and o 11Calmodulin 1 (phosphorylasCaudate down HTT, interac 14 VesiclesCaveolin 1, caveolae proteCaudate UP, HTT interac 7 Golgi apparatusDihydrolipoamide dehydr Caudate down HTT, interac 7 MitochondriaTumor protein p53 Caudate UP, HTT interac 17 Nucleus but not nucleoliSmall nuclear ribonucleopCo-expressGenefriends, Co 2 Nucleus but not nucleoliSyntaxin 1A (brain) Caudate down, Hdsi, HTT i 7Glucose-6-phosphate isomCaudate down, Hdsi, HTT i 19 Plasma membrane, CytoplaNADH dehydrogenase (ubiqHTT interacting proteins 11CREB binding protein Caudate UP, Co-expressdb 16 Nucleus but not nucleoliCathepsin D Caudate UP, HDsi 11Dynamin 1-like Caudate down HTT, interac 12 Cytoplasm, VesiclesDynamin 2 Caudate UP, Co-expressdb 19 Cytoplasm, Golgi apparatuV-akt murine thymoma virHTT interacting proteins 14 Nucleus, Cytoskeleton (MiCaspase 8, apoptosis-relatHTT interacting proteins 2 Cytoplasm, Nucleus but noCystathionine-beta-synthaCaudate UP, HTT interac 21 Nucleoli, Vesicles

Expression status No of tissue expressed Enhanced/enriched Drug targetsExpressed in all 32 Probable drugExpressed in all 32 Probable drugExpressed in all 32 Probable drugTissue enhanced 31 lung Probable drugExpressed in all 32 Probable drugExpressed in all 32 Probable drugExpressed in all 32 Probable drugTissue enhanced 30 brain Probable drugExpressed in all 32 Probable drugExpressed in all 32 Probable drugExpressed in all 32 Probable drugExpressed in all 32 Probable drugExpressed in all 32 Probable drugExpressed in all 32 Probable drugExpressed in all 32 Probable drugExpressed in all 32 Probable drugTissue enhanced 29 liver, pancreas Probable drug

Supplementary Table S8E: HD associated genes that are FDA approved drug targets with TVS TVS Gene symbol

4 ADORA2A /A2AR3.5 ATP1A13.5 BCL23.5 CNR13.5 DRD13.5 GRIN1

3 GRIN2A3 HDAC13 HDAC23 HDAC33 MAPK13 NFKB13 SLC25A43 SNAP253 TUBB

2.52

Supplementary Table S8E: HD associated genes that are FDA approved drug targets with TVS Other symbol Description HD association ChromosomeADORA2, RDC8 Adenosine A2a receptor Caudate down, AAO 22

ATPase, Na+/K+ transportiCaudate down HTT, interac 1Bcl-2, PPP1R50 B-cell CLL/lymphoma 2 Caudate UP, Co-expressGen 18CANN6, CB-R, CB1, CB1A, Cannabinoid receptor 1 (brAO, Caudate down 6

Dopamine receptor D1 Functinally related and o 5GluN1, NMDAR1 Glutamate receptor, ionotropic, N-methyl D-aspartat 9GluN2A, NMDAR2A Glutamate receptor, ionotAO, Caudate down, HDsi 16GON-10, HD1, RPD3L1 Histone deacetylase 1 Functinally related and o 1RPD3, YAF1 Histone deacetylase 2 Caudate down, HDsi 6HD3, RPD3, RPD3-2 Histone deacetylase 3 Functinally related and o 5ERK, ERK2, MAPK2, p41m Mitogen-activated proteinCaudate down, HDsi 22KBF1, NF-kappaB, NF-kB1,Nuclear factor of kappa li Co-expressGenefriends, H 4ANT1, PEO2, PEO3, T1 Solute carrier family 25 ( Caudate down, Hdsi, HTT i 4bA416N4.2, dJ1068F16.2, RSynaptosomal-associated Caudate down, Hdsi, HTT i 20M40, MGC16435, OK/SW-clTubulin, beta class I Caudate down HTT, interac 6

Localization Expression status No of tissue expressed Enhanced/enrichedTissue enhanced 8 brain,pancreas,stomachExpressed in all 32Expressed in all 32Tissue enhanced 20 brainTissue enhanced 3 brainTissue enriched 8 brainTissue enhanced 6 brain

Nucleus but not nucleoli Expressed in all 32Nucleus Expressed in all 32Nucleus but not nucleoli, Expressed in all 32Nucleus but not nucleoli, Expressed in all 32Nucleus but not nucleoli, Expressed in all 32

Group enriched 32 heart muscle,skeletal musCytoplasm, Golgi apparatusTissue enriched 20 brain

Expressed in all 32

Drug targets TVSFDA approved small molecules/Biote 4FDA approved small molecules/Biote 3FDA approved small molecules/Biote 2FDA approved small molecules/Biote 3FDA approved small molecules/Biote 3FDA approved small molecules/Biote 4.5FDA approved small molecules/Biote 2.5FDA approved small molecules/Biote 4FDA approved small molecules/Biote 1FDA approved small molecules/Biote 1FDA approved small molecules/Biote 2.5FDA approved small molecules/Biote 2FDA approved small molecules/Biote 2FDA approved small molecules/Biote 3FDA approved small molecules/Biote 3

Supplementary Table S8F: HD associated proteins without TVS but either known targets of FDA approved drug or potential drug targetsGene symbolCACNA2D1CPT2EGFRFADS1GSSHMGCRKCNC1MTORNR3C1PAHTNFRSF8TUBG1VAMP2PRKAA1ADARALDOAAPPASNSATP2A2BAP1CASKCASP10CHD8CTHCTNSENTPD1GPHNHADHAINPPL1LDHANDUFS1NUP98PFKMPGM1POMT2PPIBPTK2BSLC16A1SLC25A12SLC25A13SLC25A3

SNCASPG7SUCLA2SYPTMPRSS5TYK2UQCRC2WHSC1

Supplementary Table S8F: HD associated proteins without TVS but either known targets of FDA approved drug or potential drug targetsOther symbol Description HD association ChromosomeCACNA2, CACNL2A, LCalcium channel, voltageCaudate down HTT, interac 7CPT1, CPTASE Carnitine palmitoyltransCaudate UP, HDsi 1ERBB, ERBB1 Epidermal growth factor Caudate UP, HTT interac 7D5D, FADS6, FADSD5,Fatty acid desaturase 1 Caudate UP, HDsi 11

Glutathione synthetase Caudate down, HDsi 203-hydroxy-3-methylglutaCaudate down, HDsi 5

Kv3.1 Potassium voltage-gatedCaudate down, HDsi 11FLJ44809, FRAP, FRAPMechanistic target of ra Co-expressdb, HTT interact 1GR, GRL Nuclear receptor subfamiCaudate UP, HDsi 5PH Phenylalanine hydroxylaCaudate UP, HDsi 12CD30, D1S166E, KI-1 Tumor necrosis factor r Caudate down, Co-expressG 1TUBG, TUBGCP1 Tubulin, gamma 1 Hdsi, HTT interacting prot 17SYB2, VAMP-2 Vesicle-associated membCaudate down HTT, interac 17AMPKa1 Protein kinase, AMP-activaFunctinally related but n 5ADAR1, G1P1, IFI4 Adenosine deaminase, RCo-expressGenefriends, Co 1

Aldolase A, fructose-bi Caudate down, Hdsi, HTT i 16AD1 Amyloid beta (A4) precuCaudate down, HDsi 21

Asparagine synthetase ( Caudate down, HDsi 7ATP2B, DAR, SERCA2ATPase, Ca++ transportinCaudate down HTT, interac 12hucep-6, KIAA0272, U BRCA1 associated proteiCaudate down, Co-expressd 3CAGH39, FGS4, LIN2, Calcium/calmodulin-depCaudate UP, HDsi XMCH4 Caspase 10, apoptosis-reHTT interacting proteins 2DUPLIN, HELSNF1, KChromodomain helicase Co-expressGenefriends, Co 14

Cystathionase (cystathi Caudate UP, HDsi 1CTNS-LSB, PQLC4 Cystinosin, lysosomal cyCaudate UP, HDsi 17ATPDase, CD39, NTPDaEctonucleoside triphosp Caudate UP, Co-expressGe 10KIAA1385 Gephyrin Caudate down, Co-expressG 14GBP, LCEH, LCHAD, Hydroxyacyl-CoA dehydroCaudate UP, HTT interac 2SHIP2 Inositol polyphosphate pCaudate UP, Co-expressdb 11

Lactate dehydrogenase Caudate down HTT, interac 11CI-75k NADH dehydrogenase (ubCaudate down HTT, interac 2NUP96 Nucleoporin 98kDa Caudate UP, HDsi 11PFK-1, PFKX Phosphofructokinase, muCaudate down, Hdsi, HTT i 12

Phosphoglucomutase 1 Caudate UP, HDsi 1LGMD2N Protein-O-mannosyltransCaudate UP, Co-expressdb 14CYPB, OI9 Peptidylprolyl isomeraseCaudate UP, HTT interac 15CADTK, CAKB, FAK2,Protein tyrosine kinase 2Caudate down, Co-expressG 8MCT, MCT1 Solute carrier family 16 Caudate UP, HTT interac 1Aralar Solute carrier family 25 Caudate down, HTT interac 2ARALAR2, CITRIN, C Solute carrier family 25 Caudate UP, HTT interac 7PHC Solute carrier family 25 Caudate down, HTT interac 12

alpha-synuclein, NACP Synuclein, alpha (non AFunctinally related and o 4CAR, CMAR, SPG5C Spastic paraplegia 7 (pu Caudate UP, Co-expressdb 16

Succinate-CoA ligase, ACaudate down, HTT interac 13Synaptophysin Caudate down, HTT interac X

MGC141886, MGC1480Transmembrane protease,Caudate UP, HDsi 11JTK1 Tyrosine kinase 2 Caudate UP, Co-expressGe 19QCR2, UQCR2 Ubiquinol-cytochrome c rCaudate down, HTT interac 16MMSET, NSD2 Wolf-Hirschhorn syndroCaudate down, Co-expressd 4

Supplementary Table S8F: HD associated proteins without TVS but either known targets of FDA approved drug or potential drug targetsLocalization Expression status No of tissue expressed Enhanced/enriched

Mixed 30Nucleus but not nucleoliExpressed in all 32Plasma membrane, CytoTissue enhanced 31 placenta

Expressed in all 32Nucleoli, Cytoplasm Expressed in all 32

Expressed in all 32Tissue enriched 2 brainExpressed in all 32

Nucleus but not nucleol Expressed in all 32Cytoplasm, CytoskeletonTissue enhanced 8 kidney, liver

Mixed 10Expressed in all 32Expressed in all 32

Nucleus Expressed in all 32Nucleus, Nucleoli Expressed in all 32Cytoplasm Expressed in all 32Golgi apparatus, VesicleExpressed in all 32Cytoplasm Expressed in all 32

Expressed in all 32Nucleus but not nucleoliExpressed in all 32Nucleus but not nucleoliExpressed in all 32

Expressed in all 32Nucleus but not nucleoliExpressed in all 32Nucleus, Cytoplasm Tissue enhanced 31 liverVesicles, Cytoskeleton (Expressed in all 32Cytoskeleton (MicrotubuExpressed in all 32

Expressed in all 32Mitochondria Expressed in all 32Cytoplasm, Golgi apparaExpressed in all 32Cytoplasm, Vesicles Expressed in all 32Mitochondria Expressed in all 32

Expressed in all 32Endoplasmic reticulum Group enriched 32 heart muscle,skeletal musCytoskeleton (Actin fila Expressed in all 32

Expressed in all 32Nucleus, Nucleoli, Cyto Expressed in all 32Nucleus but not nucleoliExpressed in all 32Plasma membrane Expressed in all 32Nucleus but not nucleoliExpressed in all 32Mitochondria Expressed in all 32Mitochondria Expressed in all 32

Tissue enhanced 31 bone marrow, brainExpressed in all 32

Mitochondria Expressed in all 32Tissue enriched 20 brainTissue enhanced 5 brain, salivary gland

Cytoplasm Expressed in all 32Mitochondria Expressed in all 32Nucleus Expressed in all 32

Drug targetsFDA approved small molecules/BiotechFDA approved small molecules/BiotechFDA approved small molecules/BiotechFDA approved small molecules/BiotechFDA approved small molecules/BiotechFDA approved small molecules/BiotechFDA approved small molecules/BiotechFDA approved small molecules/BiotechFDA approved small molecules/BiotechFDA approved small molecules/BiotechFDA approved small molecules/BiotechFDA approved small molecules/BiotechFDA approved small molecules/BiotechFDA approved small molecules/BiotechProbable drugProbable drugProbable drugProbable drugProbable drugProbable drugProbable drugProbable drugProbable drugProbable drugProbable drugProbable drugProbable drugProbable drugProbable drugProbable drugProbable drugProbable drugProbable drugProbable drugProbable drugProbable drugProbable drugProbable drugProbable drugProbable drugProbable drug

Probable drugProbable drugProbable drugProbable drugProbable drugProbable drugProbable drugProbable drug

Supplementary Table S9A: Biological Processes and KEGG pathways connected with HD associated genes with TVS and targets of FDA approved drugs or potential targets o f drugsGene symbol Description ITPR1 Inositol 1,4,5-trisphosphate receptor, type 1ITPR1 Inositol 1,4,5-trisphosphate receptor, type 1ITPR1 Inositol 1,4,5-trisphosphate receptor, type 1ITPR1 Inositol 1,4,5-trisphosphate receptor, type 1ITPR1 Inositol 1,4,5-trisphosphate receptor, type 1ITPR1 Inositol 1,4,5-trisphosphate receptor, type 1ITPR1 Inositol 1,4,5-trisphosphate receptor, type 1ITPR1 Inositol 1,4,5-trisphosphate receptor, type 1ITPR1 Inositol 1,4,5-trisphosphate receptor, type 1ITPR1 Inositol 1,4,5-trisphosphate receptor, type 1ITPR1 Inositol 1,4,5-trisphosphate receptor, type 1ITPR1 Inositol 1,4,5-trisphosphate receptor, type 1ITPR1 Inositol 1,4,5-trisphosphate receptor, type 1ITPR1 Inositol 1,4,5-trisphosphate receptor, type 1ITPR1 Inositol 1,4,5-trisphosphate receptor, type 1ITPR1 Inositol 1,4,5-trisphosphate receptor, type 1ITPR1 Inositol 1,4,5-trisphosphate receptor, type 1ITPR1 Inositol 1,4,5-trisphosphate receptor, type 1ITPR1 Inositol 1,4,5-trisphosphate receptor, type 1ITPR1 Inositol 1,4,5-trisphosphate receptor, type 1ITPR1 Inositol 1,4,5-trisphosphate receptor, type 1ITPR1 Inositol 1,4,5-trisphosphate receptor, type 1ITPR1 Inositol 1,4,5-trisphosphate receptor, type 1ITPR1 Inositol 1,4,5-trisphosphate receptor, type 1ITPR1 Inositol 1,4,5-trisphosphate receptor, type 1ITPR1 Inositol 1,4,5-trisphosphate receptor, type 1ITPR1 Inositol 1,4,5-trisphosphate receptor, type 1ITPR1 Inositol 1,4,5-trisphosphate receptor, type 1ITPR1 Inositol 1,4,5-trisphosphate receptor, type 1ITPR1 Inositol 1,4,5-trisphosphate receptor, type 1ATM Ataxia telangiectasia mutatedATM Ataxia telangiectasia mutatedATM Ataxia telangiectasia mutatedATM Ataxia telangiectasia mutatedATM Ataxia telangiectasia mutatedATM Ataxia telangiectasia mutatedATM Ataxia telangiectasia mutatedATM Ataxia telangiectasia mutatedATM Ataxia telangiectasia mutatedATM Ataxia telangiectasia mutatedATM Ataxia telangiectasia mutatedATM Ataxia telangiectasia mutatedATM Ataxia telangiectasia mutatedATM Ataxia telangiectasia mutated

ATM Ataxia telangiectasia mutatedATM Ataxia telangiectasia mutatedATM Ataxia telangiectasia mutatedATM Ataxia telangiectasia mutatedATM Ataxia telangiectasia mutatedATM Ataxia telangiectasia mutatedATM Ataxia telangiectasia mutatedATM Ataxia telangiectasia mutatedATM Ataxia telangiectasia mutatedATM Ataxia telangiectasia mutatedATM Ataxia telangiectasia mutatedATM Ataxia telangiectasia mutatedATM Ataxia telangiectasia mutatedATM Ataxia telangiectasia mutatedATM Ataxia telangiectasia mutatedATM Ataxia telangiectasia mutatedATM Ataxia telangiectasia mutatedATM Ataxia telangiectasia mutatedATM Ataxia telangiectasia mutatedATM Ataxia telangiectasia mutatedATM Ataxia telangiectasia mutatedATM Ataxia telangiectasia mutatedATM Ataxia telangiectasia mutatedATM Ataxia telangiectasia mutatedATM Ataxia telangiectasia mutatedATM Ataxia telangiectasia mutatedATM Ataxia telangiectasia mutatedATM Ataxia telangiectasia mutatedCALM1 Calmodulin 1 (phosphorylase kinase, delta)CALM1 Calmodulin 1 (phosphorylase kinase, delta)CALM1 Calmodulin 1 (phosphorylase kinase, delta)CALM1 Calmodulin 1 (phosphorylase kinase, delta)CALM1 Calmodulin 1 (phosphorylase kinase, delta)CALM1 Calmodulin 1 (phosphorylase kinase, delta)CALM1 Calmodulin 1 (phosphorylase kinase, delta)CALM1 Calmodulin 1 (phosphorylase kinase, delta)CALM1 Calmodulin 1 (phosphorylase kinase, delta)CALM1 Calmodulin 1 (phosphorylase kinase, delta)CALM1 Calmodulin 1 (phosphorylase kinase, delta)CALM1 Calmodulin 1 (phosphorylase kinase, delta)CALM1 Calmodulin 1 (phosphorylase kinase, delta)CALM1 Calmodulin 1 (phosphorylase kinase, delta)CALM1 Calmodulin 1 (phosphorylase kinase, delta)CALM1 Calmodulin 1 (phosphorylase kinase, delta)CALM1 Calmodulin 1 (phosphorylase kinase, delta)CALM1 Calmodulin 1 (phosphorylase kinase, delta)

CALM1 Calmodulin 1 (phosphorylase kinase, delta)CALM1 Calmodulin 1 (phosphorylase kinase, delta)CALM1 Calmodulin 1 (phosphorylase kinase, delta)CALM1 Calmodulin 1 (phosphorylase kinase, delta)CALM1 Calmodulin 1 (phosphorylase kinase, delta)CALM1 Calmodulin 1 (phosphorylase kinase, delta)CALM1 Calmodulin 1 (phosphorylase kinase, delta)CALM1 Calmodulin 1 (phosphorylase kinase, delta)CALM1 Calmodulin 1 (phosphorylase kinase, delta)CALM1 Calmodulin 1 (phosphorylase kinase, delta)CALM1 Calmodulin 1 (phosphorylase kinase, delta)CALM1 Calmodulin 1 (phosphorylase kinase, delta)CALM1 Calmodulin 1 (phosphorylase kinase, delta)CALM1 Calmodulin 1 (phosphorylase kinase, delta)CALM1 Calmodulin 1 (phosphorylase kinase, delta)CALM1 Calmodulin 1 (phosphorylase kinase, delta)CALM1 Calmodulin 1 (phosphorylase kinase, delta)CALM1 Calmodulin 1 (phosphorylase kinase, delta)CAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDa

CAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDaCAV1 Caveolin 1, caveolae protein, 22kDa

DLD Dihydrolipoamide dehydrogenaseDLD Dihydrolipoamide dehydrogenaseDLD Dihydrolipoamide dehydrogenaseDLD Dihydrolipoamide dehydrogenaseDLD Dihydrolipoamide dehydrogenaseDLD Dihydrolipoamide dehydrogenaseDLD Dihydrolipoamide dehydrogenaseDLD Dihydrolipoamide dehydrogenaseDLD Dihydrolipoamide dehydrogenaseDLD Dihydrolipoamide dehydrogenaseDLD Dihydrolipoamide dehydrogenaseDLD Dihydrolipoamide dehydrogenaseDLD Dihydrolipoamide dehydrogenaseDLD Dihydrolipoamide dehydrogenaseDLD Dihydrolipoamide dehydrogenaseTP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53

TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53

TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53TP53 Tumor protein p53SNRNP200 Small nuclear ribonucleoprotein 200kDa (U5)SNRNP200 Small nuclear ribonucleoprotein 200kDa (U5)SNRNP200 Small nuclear ribonucleoprotein 200kDa (U5)SNRNP200 Small nuclear ribonucleoprotein 200kDa (U5)STX1A Syntaxin 1A (brain)STX1A Syntaxin 1A (brain)STX1A Syntaxin 1A (brain)STX1A Syntaxin 1A (brain)STX1A Syntaxin 1A (brain)STX1A Syntaxin 1A (brain)STX1A Syntaxin 1A (brain)STX1A Syntaxin 1A (brain)STX1A Syntaxin 1A (brain)STX1A Syntaxin 1A (brain)STX1A Syntaxin 1A (brain)STX1A Syntaxin 1A (brain)STX1A Syntaxin 1A (brain)STX1A Syntaxin 1A (brain)STX1A Syntaxin 1A (brain)GPI Glucose-6-phosphate isomeraseGPI Glucose-6-phosphate isomeraseGPI Glucose-6-phosphate isomeraseGPI Glucose-6-phosphate isomeraseGPI Glucose-6-phosphate isomeraseGPI Glucose-6-phosphate isomeraseGPI Glucose-6-phosphate isomeraseGPI Glucose-6-phosphate isomerase

GPI Glucose-6-phosphate isomeraseGPI Glucose-6-phosphate isomeraseGPI Glucose-6-phosphate isomeraseGPI Glucose-6-phosphate isomeraseGPI Glucose-6-phosphate isomeraseGPI Glucose-6-phosphate isomeraseNDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDaNDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDaNDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDaNDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDaNDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDaNDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDaCREBBP CREB binding proteinCREBBP CREB binding proteinCREBBP CREB binding proteinCREBBP CREB binding proteinCREBBP CREB binding proteinCREBBP CREB binding proteinCREBBP CREB binding proteinCREBBP CREB binding proteinCREBBP CREB binding proteinCREBBP CREB binding proteinCREBBP CREB binding proteinCREBBP CREB binding proteinCREBBP CREB binding proteinCREBBP CREB binding proteinCREBBP CREB binding proteinCREBBP CREB binding proteinCREBBP CREB binding proteinCREBBP CREB binding proteinCREBBP CREB binding proteinCREBBP CREB binding proteinCREBBP CREB binding proteinCREBBP CREB binding proteinCREBBP CREB binding proteinCREBBP CREB binding proteinCREBBP CREB binding proteinCTSD Cathepsin DCTSD Cathepsin DCTSD Cathepsin DCTSD Cathepsin DCTSD Cathepsin DCTSD Cathepsin DCTSD Cathepsin DDNM1L Dynamin 1-likeDNM1L Dynamin 1-like

DNM1L Dynamin 1-likeDNM1L Dynamin 1-likeDNM1L Dynamin 1-likeDNM1L Dynamin 1-likeDNM1L Dynamin 1-likeDNM1L Dynamin 1-likeDNM1L Dynamin 1-likeDNM1L Dynamin 1-likeDNM1L Dynamin 1-likeDNM1L Dynamin 1-likeDNM1L Dynamin 1-likeDNM1L Dynamin 1-likeDNM1L Dynamin 1-likeDNM2 Dynamin 2DNM2 Dynamin 2DNM2 Dynamin 2DNM2 Dynamin 2DNM2 Dynamin 2DNM2 Dynamin 2DNM2 Dynamin 2DNM2 Dynamin 2DNM2 Dynamin 2DNM2 Dynamin 2DNM2 Dynamin 2DNM2 Dynamin 2DNM2 Dynamin 2DNM2 Dynamin 2DNM2 Dynamin 2DNM2 Dynamin 2DNM2 Dynamin 2AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1

AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1

AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1AKT1 V-akt murine thymoma viral oncogene homolog 1CASP8 Caspase 8, apoptosis-related cysteine peptidaseCASP8 Caspase 8, apoptosis-related cysteine peptidaseCASP8 Caspase 8, apoptosis-related cysteine peptidaseCASP8 Caspase 8, apoptosis-related cysteine peptidaseCASP8 Caspase 8, apoptosis-related cysteine peptidaseCASP8 Caspase 8, apoptosis-related cysteine peptidase

CASP8 Caspase 8, apoptosis-related cysteine peptidaseCASP8 Caspase 8, apoptosis-related cysteine peptidaseCASP8 Caspase 8, apoptosis-related cysteine peptidaseCASP8 Caspase 8, apoptosis-related cysteine peptidaseCASP8 Caspase 8, apoptosis-related cysteine peptidaseCASP8 Caspase 8, apoptosis-related cysteine peptidaseCASP8 Caspase 8, apoptosis-related cysteine peptidaseCASP8 Caspase 8, apoptosis-related cysteine peptidaseCASP8 Caspase 8, apoptosis-related cysteine peptidaseCASP8 Caspase 8, apoptosis-related cysteine peptidaseCASP8 Caspase 8, apoptosis-related cysteine peptidaseCASP8 Caspase 8, apoptosis-related cysteine peptidaseCASP8 Caspase 8, apoptosis-related cysteine peptidaseCASP8 Caspase 8, apoptosis-related cysteine peptidaseCASP8 Caspase 8, apoptosis-related cysteine peptidaseCASP8 Caspase 8, apoptosis-related cysteine peptidaseCASP8 Caspase 8, apoptosis-related cysteine peptidaseCASP8 Caspase 8, apoptosis-related cysteine peptidaseCASP8 Caspase 8, apoptosis-related cysteine peptidaseCASP8 Caspase 8, apoptosis-related cysteine peptidaseCASP8 Caspase 8, apoptosis-related cysteine peptidaseCASP8 Caspase 8, apoptosis-related cysteine peptidaseCASP8 Caspase 8, apoptosis-related cysteine peptidaseCASP8 Caspase 8, apoptosis-related cysteine peptidaseCASP8 Caspase 8, apoptosis-related cysteine peptidaseCASP8 Caspase 8, apoptosis-related cysteine peptidaseCASP8 Caspase 8, apoptosis-related cysteine peptidaseCASP8 Caspase 8, apoptosis-related cysteine peptidaseCASP8 Caspase 8, apoptosis-related cysteine peptidaseCASP8 Caspase 8, apoptosis-related cysteine peptidaseCASP8 Caspase 8, apoptosis-related cysteine peptidaseCBS Cystathionine-beta-synthaseCBS Cystathionine-beta-synthaseCBS Cystathionine-beta-synthaseCBS Cystathionine-beta-synthaseCBS Cystathionine-beta-synthaseCBS Cystathionine-beta-synthaseCBS Cystathionine-beta-synthaseCBS Cystathionine-beta-synthaseCBS Cystathionine-beta-synthaseCBS Cystathionine-beta-synthaseCBS Cystathionine-beta-synthaseCBS Cystathionine-beta-synthaseCBS Cystathionine-beta-synthaseCBS Cystathionine-beta-synthaseCBS Cystathionine-beta-synthase

CBS Cystathionine-beta-synthaseCBS Cystathionine-beta-synthaseCBS Cystathionine-beta-synthaseCBS Cystathionine-beta-synthaseCBS Cystathionine-beta-synthaseCBS Cystathionine-beta-synthaseCBS Cystathionine-beta-synthaseCBS Cystathionine-beta-synthaseCBS Cystathionine-beta-synthaseCBS Cystathionine-beta-synthaseCBS Cystathionine-beta-synthaseADORA2A / Adenosine A2a receptorADORA2A / Adenosine A2a receptorADORA2A / Adenosine A2a receptorADORA2A / Adenosine A2a receptorADORA2A / Adenosine A2a receptorADORA2A / Adenosine A2a receptorADORA2A / Adenosine A2a receptorADORA2A / Adenosine A2a receptorADORA2A / Adenosine A2a receptorADORA2A / Adenosine A2a receptorADORA2A / Adenosine A2a receptorADORA2A / Adenosine A2a receptorADORA2A / Adenosine A2a receptorADORA2A / Adenosine A2a receptorADORA2A / Adenosine A2a receptorADORA2A / Adenosine A2a receptorADORA2A / Adenosine A2a receptorADORA2A / Adenosine A2a receptorADORA2A / Adenosine A2a receptorADORA2A / Adenosine A2a receptorADORA2A / Adenosine A2a receptorADORA2A / Adenosine A2a receptorADORA2A / Adenosine A2a receptorADORA2A / Adenosine A2a receptorADORA2A / Adenosine A2a receptorADORA2A / Adenosine A2a receptorADORA2A / Adenosine A2a receptorADORA2A / Adenosine A2a receptorADORA2A / Adenosine A2a receptorADORA2A / Adenosine A2a receptorADORA2A / Adenosine A2a receptorADORA2A / Adenosine A2a receptorADORA2A / Adenosine A2a receptorADORA2A / Adenosine A2a receptorADORA2A / Adenosine A2a receptor

ADORA2A / Adenosine A2a receptorADORA2A / Adenosine A2a receptorADORA2A / Adenosine A2a receptorADORA2A / Adenosine A2a receptorADORA2A / Adenosine A2a receptorADORA2A / Adenosine A2a receptorADORA2A / Adenosine A2a receptorADORA2A / Adenosine A2a receptorADORA2A / Adenosine A2a receptorADORA2A / Adenosine A2a receptorADORA2A / Adenosine A2a receptorADORA2A / Adenosine A2a receptorADORA2A / Adenosine A2a receptorADORA2A / Adenosine A2a receptorADORA2A / Adenosine A2a receptorADORA2A / Adenosine A2a receptorADORA2A / Adenosine A2a receptorADORA2A / Adenosine A2a receptorADORA2A / Adenosine A2a receptorADORA2A / Adenosine A2a receptorADORA2A / Adenosine A2a receptorATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptideATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptideATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptideATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptideATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptideATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptideATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptideATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptideATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptideATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptideATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptideATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptideATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptideATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptideATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptideATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptideATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptideATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptideATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptideBCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2

BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2

BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2BCL2 B-cell CLL/lymphoma 2CNR1 Cannabinoid receptor 1 (brain)CNR1 Cannabinoid receptor 1 (brain)CNR1 Cannabinoid receptor 1 (brain)CNR1 Cannabinoid receptor 1 (brain)CNR1 Cannabinoid receptor 1 (brain)CNR1 Cannabinoid receptor 1 (brain)

CNR1 Cannabinoid receptor 1 (brain)CNR1 Cannabinoid receptor 1 (brain)CNR1 Cannabinoid receptor 1 (brain)CNR1 Cannabinoid receptor 1 (brain)CNR1 Cannabinoid receptor 1 (brain)CNR1 Cannabinoid receptor 1 (brain)CNR1 Cannabinoid receptor 1 (brain)CNR1 Cannabinoid receptor 1 (brain)CNR1 Cannabinoid receptor 1 (brain)CNR1 Cannabinoid receptor 1 (brain)CNR1 Cannabinoid receptor 1 (brain)CNR1 Cannabinoid receptor 1 (brain)CNR1 Cannabinoid receptor 1 (brain)CNR1 Cannabinoid receptor 1 (brain)CNR1 Cannabinoid receptor 1 (brain)CNR1 Cannabinoid receptor 1 (brain)CNR1 Cannabinoid receptor 1 (brain)CNR1 Cannabinoid receptor 1 (brain)CNR1 Cannabinoid receptor 1 (brain)CNR1 Cannabinoid receptor 1 (brain)CNR1 Cannabinoid receptor 1 (brain)CNR1 Cannabinoid receptor 1 (brain)CNR1 Cannabinoid receptor 1 (brain)CNR1 Cannabinoid receptor 1 (brain)CNR1 Cannabinoid receptor 1 (brain)CNR1 Cannabinoid receptor 1 (brain)CNR1 Cannabinoid receptor 1 (brain)CNR1 Cannabinoid receptor 1 (brain)CNR1 Cannabinoid receptor 1 (brain)CNR1 Cannabinoid receptor 1 (brain)DRD1 Dopamine receptor D1DRD1 Dopamine receptor D1DRD1 Dopamine receptor D1DRD1 Dopamine receptor D1DRD1 Dopamine receptor D1DRD1 Dopamine receptor D1DRD1 Dopamine receptor D1DRD1 Dopamine receptor D1DRD1 Dopamine receptor D1DRD1 Dopamine receptor D1DRD1 Dopamine receptor D1DRD1 Dopamine receptor D1DRD1 Dopamine receptor D1DRD1 Dopamine receptor D1DRD1 Dopamine receptor D1DRD1 Dopamine receptor D1

DRD1 Dopamine receptor D1DRD1 Dopamine receptor D1DRD1 Dopamine receptor D1DRD1 Dopamine receptor D1DRD1 Dopamine receptor D1DRD1 Dopamine receptor D1DRD1 Dopamine receptor D1DRD1 Dopamine receptor D1DRD1 Dopamine receptor D1DRD1 Dopamine receptor D1DRD1 Dopamine receptor D1DRD1 Dopamine receptor D1DRD1 Dopamine receptor D1DRD1 Dopamine receptor D1DRD1 Dopamine receptor D1DRD1 Dopamine receptor D1DRD1 Dopamine receptor D1DRD1 Dopamine receptor D1DRD1 Dopamine receptor D1DRD1 Dopamine receptor D1DRD1 Dopamine receptor D1DRD1 Dopamine receptor D1DRD1 Dopamine receptor D1DRD1 Dopamine receptor D1DRD1 Dopamine receptor D1DRD1 Dopamine receptor D1DRD1 Dopamine receptor D1DRD1 Dopamine receptor D1DRD1 Dopamine receptor D1DRD1 Dopamine receptor D1DRD1 Dopamine receptor D1DRD1 Dopamine receptor D1DRD1 Dopamine receptor D1DRD1 Dopamine receptor D1DRD1 Dopamine receptor D1DRD1 Dopamine receptor D1DRD1 Dopamine receptor D1DRD1 Dopamine receptor D1DRD1 Dopamine receptor D1GRIN1 Glutamate receptor, ionotropic, N-methyl D-aspartate 1GRIN1 Glutamate receptor, ionotropic, N-methyl D-aspartate 1GRIN1 Glutamate receptor, ionotropic, N-methyl D-aspartate 1GRIN1 Glutamate receptor, ionotropic, N-methyl D-aspartate 1GRIN1 Glutamate receptor, ionotropic, N-methyl D-aspartate 1GRIN1 Glutamate receptor, ionotropic, N-methyl D-aspartate 1GRIN1 Glutamate receptor, ionotropic, N-methyl D-aspartate 1

GRIN1 Glutamate receptor, ionotropic, N-methyl D-aspartate 1GRIN1 Glutamate receptor, ionotropic, N-methyl D-aspartate 1GRIN1 Glutamate receptor, ionotropic, N-methyl D-aspartate 1GRIN1 Glutamate receptor, ionotropic, N-methyl D-aspartate 1GRIN1 Glutamate receptor, ionotropic, N-methyl D-aspartate 1GRIN1 Glutamate receptor, ionotropic, N-methyl D-aspartate 1GRIN1 Glutamate receptor, ionotropic, N-methyl D-aspartate 1GRIN1 Glutamate receptor, ionotropic, N-methyl D-aspartate 1GRIN1 Glutamate receptor, ionotropic, N-methyl D-aspartate 1GRIN1 Glutamate receptor, ionotropic, N-methyl D-aspartate 1GRIN1 Glutamate receptor, ionotropic, N-methyl D-aspartate 1GRIN1 Glutamate receptor, ionotropic, N-methyl D-aspartate 1GRIN1 Glutamate receptor, ionotropic, N-methyl D-aspartate 1GRIN1 Glutamate receptor, ionotropic, N-methyl D-aspartate 1GRIN1 Glutamate receptor, ionotropic, N-methyl D-aspartate 1GRIN1 Glutamate receptor, ionotropic, N-methyl D-aspartate 1GRIN1 Glutamate receptor, ionotropic, N-methyl D-aspartate 1GRIN1 Glutamate receptor, ionotropic, N-methyl D-aspartate 1GRIN1 Glutamate receptor, ionotropic, N-methyl D-aspartate 1GRIN1 Glutamate receptor, ionotropic, N-methyl D-aspartate 1GRIN1 Glutamate receptor, ionotropic, N-methyl D-aspartate 1GRIN1 Glutamate receptor, ionotropic, N-methyl D-aspartate 1GRIN1 Glutamate receptor, ionotropic, N-methyl D-aspartate 1GRIN1 Glutamate receptor, ionotropic, N-methyl D-aspartate 1GRIN1 Glutamate receptor, ionotropic, N-methyl D-aspartate 1GRIN1 Glutamate receptor, ionotropic, N-methyl D-aspartate 1GRIN1 Glutamate receptor, ionotropic, N-methyl D-aspartate 1GRIN1 Glutamate receptor, ionotropic, N-methyl D-aspartate 1GRIN1 Glutamate receptor, ionotropic, N-methyl D-aspartate 1GRIN1 Glutamate receptor, ionotropic, N-methyl D-aspartate 1GRIN1 Glutamate receptor, ionotropic, N-methyl D-aspartate 1GRIN1 Glutamate receptor, ionotropic, N-methyl D-aspartate 1GRIN1 Glutamate receptor, ionotropic, N-methyl D-aspartate 1GRIN1 Glutamate receptor, ionotropic, N-methyl D-aspartate 1GRIN1 Glutamate receptor, ionotropic, N-methyl D-aspartate 1GRIN1 Glutamate receptor, ionotropic, N-methyl D-aspartate 1GRIN1 Glutamate receptor, ionotropic, N-methyl D-aspartate 1GRIN1 Glutamate receptor, ionotropic, N-methyl D-aspartate 1GRIN1 Glutamate receptor, ionotropic, N-methyl D-aspartate 1GRIN1 Glutamate receptor, ionotropic, N-methyl D-aspartate 1GRIN1 Glutamate receptor, ionotropic, N-methyl D-aspartate 1GRIN1 Glutamate receptor, ionotropic, N-methyl D-aspartate 1GRIN1 Glutamate receptor, ionotropic, N-methyl D-aspartate 1GRIN1 Glutamate receptor, ionotropic, N-methyl D-aspartate 1GRIN1 Glutamate receptor, ionotropic, N-methyl D-aspartate 1GRIN1 Glutamate receptor, ionotropic, N-methyl D-aspartate 1

GRIN1 Glutamate receptor, ionotropic, N-methyl D-aspartate 1GRIN2A Glutamate receptor, ionotropic, N-methyl D-aspartate 2AGRIN2A Glutamate receptor, ionotropic, N-methyl D-aspartate 2AGRIN2A Glutamate receptor, ionotropic, N-methyl D-aspartate 2AGRIN2A Glutamate receptor, ionotropic, N-methyl D-aspartate 2AGRIN2A Glutamate receptor, ionotropic, N-methyl D-aspartate 2AGRIN2A Glutamate receptor, ionotropic, N-methyl D-aspartate 2AGRIN2A Glutamate receptor, ionotropic, N-methyl D-aspartate 2AGRIN2A Glutamate receptor, ionotropic, N-methyl D-aspartate 2AGRIN2A Glutamate receptor, ionotropic, N-methyl D-aspartate 2AGRIN2A Glutamate receptor, ionotropic, N-methyl D-aspartate 2AGRIN2A Glutamate receptor, ionotropic, N-methyl D-aspartate 2AGRIN2A Glutamate receptor, ionotropic, N-methyl D-aspartate 2AGRIN2A Glutamate receptor, ionotropic, N-methyl D-aspartate 2AGRIN2A Glutamate receptor, ionotropic, N-methyl D-aspartate 2AGRIN2A Glutamate receptor, ionotropic, N-methyl D-aspartate 2AGRIN2A Glutamate receptor, ionotropic, N-methyl D-aspartate 2AGRIN2A Glutamate receptor, ionotropic, N-methyl D-aspartate 2AGRIN2A Glutamate receptor, ionotropic, N-methyl D-aspartate 2AGRIN2A Glutamate receptor, ionotropic, N-methyl D-aspartate 2AGRIN2A Glutamate receptor, ionotropic, N-methyl D-aspartate 2AGRIN2A Glutamate receptor, ionotropic, N-methyl D-aspartate 2AGRIN2A Glutamate receptor, ionotropic, N-methyl D-aspartate 2AGRIN2A Glutamate receptor, ionotropic, N-methyl D-aspartate 2AGRIN2A Glutamate receptor, ionotropic, N-methyl D-aspartate 2AGRIN2A Glutamate receptor, ionotropic, N-methyl D-aspartate 2AGRIN2A Glutamate receptor, ionotropic, N-methyl D-aspartate 2AGRIN2A Glutamate receptor, ionotropic, N-methyl D-aspartate 2AGRIN2A Glutamate receptor, ionotropic, N-methyl D-aspartate 2AGRIN2A Glutamate receptor, ionotropic, N-methyl D-aspartate 2AGRIN2A Glutamate receptor, ionotropic, N-methyl D-aspartate 2AHDAC1 Histone deacetylase 1HDAC1 Histone deacetylase 1HDAC1 Histone deacetylase 1HDAC1 Histone deacetylase 1HDAC1 Histone deacetylase 1HDAC1 Histone deacetylase 1HDAC1 Histone deacetylase 1HDAC1 Histone deacetylase 1HDAC1 Histone deacetylase 1HDAC1 Histone deacetylase 1HDAC1 Histone deacetylase 1HDAC1 Histone deacetylase 1HDAC1 Histone deacetylase 1HDAC1 Histone deacetylase 1HDAC1 Histone deacetylase 1

HDAC1 Histone deacetylase 1HDAC1 Histone deacetylase 1HDAC1 Histone deacetylase 1HDAC1 Histone deacetylase 1HDAC1 Histone deacetylase 1HDAC1 Histone deacetylase 1HDAC1 Histone deacetylase 1HDAC1 Histone deacetylase 1HDAC1 Histone deacetylase 1HDAC1 Histone deacetylase 1HDAC1 Histone deacetylase 1HDAC1 Histone deacetylase 1HDAC1 Histone deacetylase 1HDAC1 Histone deacetylase 1HDAC1 Histone deacetylase 1HDAC1 Histone deacetylase 1HDAC2 Histone deacetylase 2HDAC2 Histone deacetylase 2HDAC2 Histone deacetylase 2HDAC2 Histone deacetylase 2HDAC2 Histone deacetylase 2HDAC2 Histone deacetylase 2HDAC2 Histone deacetylase 2HDAC2 Histone deacetylase 2HDAC2 Histone deacetylase 2HDAC2 Histone deacetylase 2HDAC2 Histone deacetylase 2HDAC2 Histone deacetylase 2HDAC2 Histone deacetylase 2HDAC2 Histone deacetylase 2HDAC2 Histone deacetylase 2HDAC2 Histone deacetylase 2HDAC2 Histone deacetylase 2HDAC2 Histone deacetylase 2HDAC2 Histone deacetylase 2HDAC2 Histone deacetylase 2HDAC2 Histone deacetylase 2HDAC2 Histone deacetylase 2HDAC2 Histone deacetylase 2HDAC2 Histone deacetylase 2HDAC2 Histone deacetylase 2HDAC2 Histone deacetylase 2HDAC2 Histone deacetylase 2HDAC2 Histone deacetylase 2HDAC2 Histone deacetylase 2HDAC2 Histone deacetylase 2

HDAC2 Histone deacetylase 2HDAC2 Histone deacetylase 2HDAC2 Histone deacetylase 2HDAC2 Histone deacetylase 2HDAC2 Histone deacetylase 2HDAC2 Histone deacetylase 2HDAC2 Histone deacetylase 2HDAC3 Histone deacetylase 3HDAC3 Histone deacetylase 3HDAC3 Histone deacetylase 3HDAC3 Histone deacetylase 3HDAC3 Histone deacetylase 3HDAC3 Histone deacetylase 3HDAC3 Histone deacetylase 3HDAC3 Histone deacetylase 3HDAC3 Histone deacetylase 3HDAC3 Histone deacetylase 3HDAC3 Histone deacetylase 3HDAC3 Histone deacetylase 3HDAC3 Histone deacetylase 3HDAC3 Histone deacetylase 3HDAC3 Histone deacetylase 3HDAC3 Histone deacetylase 3HDAC3 Histone deacetylase 3MAPK1 Mitogen-activated protein kinase 1MAPK1 Mitogen-activated protein kinase 1MAPK1 Mitogen-activated protein kinase 1MAPK1 Mitogen-activated protein kinase 1MAPK1 Mitogen-activated protein kinase 1MAPK1 Mitogen-activated protein kinase 1MAPK1 Mitogen-activated protein kinase 1MAPK1 Mitogen-activated protein kinase 1MAPK1 Mitogen-activated protein kinase 1MAPK1 Mitogen-activated protein kinase 1MAPK1 Mitogen-activated protein kinase 1MAPK1 Mitogen-activated protein kinase 1MAPK1 Mitogen-activated protein kinase 1MAPK1 Mitogen-activated protein kinase 1MAPK1 Mitogen-activated protein kinase 1MAPK1 Mitogen-activated protein kinase 1MAPK1 Mitogen-activated protein kinase 1MAPK1 Mitogen-activated protein kinase 1MAPK1 Mitogen-activated protein kinase 1MAPK1 Mitogen-activated protein kinase 1MAPK1 Mitogen-activated protein kinase 1MAPK1 Mitogen-activated protein kinase 1

MAPK1 Mitogen-activated protein kinase 1MAPK1 Mitogen-activated protein kinase 1MAPK1 Mitogen-activated protein kinase 1MAPK1 Mitogen-activated protein kinase 1MAPK1 Mitogen-activated protein kinase 1MAPK1 Mitogen-activated protein kinase 1MAPK1 Mitogen-activated protein kinase 1MAPK1 Mitogen-activated protein kinase 1MAPK1 Mitogen-activated protein kinase 1MAPK1 Mitogen-activated protein kinase 1MAPK1 Mitogen-activated protein kinase 1MAPK1 Mitogen-activated protein kinase 1MAPK1 Mitogen-activated protein kinase 1MAPK1 Mitogen-activated protein kinase 1MAPK1 Mitogen-activated protein kinase 1MAPK1 Mitogen-activated protein kinase 1MAPK1 Mitogen-activated protein kinase 1MAPK1 Mitogen-activated protein kinase 1MAPK1 Mitogen-activated protein kinase 1MAPK1 Mitogen-activated protein kinase 1MAPK1 Mitogen-activated protein kinase 1MAPK1 Mitogen-activated protein kinase 1MAPK1 Mitogen-activated protein kinase 1MAPK1 Mitogen-activated protein kinase 1MAPK1 Mitogen-activated protein kinase 1MAPK1 Mitogen-activated protein kinase 1MAPK1 Mitogen-activated protein kinase 1MAPK1 Mitogen-activated protein kinase 1MAPK1 Mitogen-activated protein kinase 1MAPK1 Mitogen-activated protein kinase 1MAPK1 Mitogen-activated protein kinase 1MAPK1 Mitogen-activated protein kinase 1MAPK1 Mitogen-activated protein kinase 1MAPK1 Mitogen-activated protein kinase 1MAPK1 Mitogen-activated protein kinase 1MAPK1 Mitogen-activated protein kinase 1MAPK1 Mitogen-activated protein kinase 1MAPK1 Mitogen-activated protein kinase 1MAPK1 Mitogen-activated protein kinase 1MAPK1 Mitogen-activated protein kinase 1MAPK1 Mitogen-activated protein kinase 1MAPK1 Mitogen-activated protein kinase 1MAPK1 Mitogen-activated protein kinase 1MAPK1 Mitogen-activated protein kinase 1MAPK1 Mitogen-activated protein kinase 1MAPK1 Mitogen-activated protein kinase 1

MAPK1 Mitogen-activated protein kinase 1MAPK1 Mitogen-activated protein kinase 1MAPK1 Mitogen-activated protein kinase 1NFKB1 Nuclear factor of kappa light polypeptide gene enhancer in NFKB1 Nuclear factor of kappa light polypeptide gene enhancer in NFKB1 Nuclear factor of kappa light polypeptide gene enhancer in NFKB1 Nuclear factor of kappa light polypeptide gene enhancer in NFKB1 Nuclear factor of kappa light polypeptide gene enhancer in NFKB1 Nuclear factor of kappa light polypeptide gene enhancer in NFKB1 Nuclear factor of kappa light polypeptide gene enhancer in NFKB1 Nuclear factor of kappa light polypeptide gene enhancer in NFKB1 Nuclear factor of kappa light polypeptide gene enhancer in NFKB1 Nuclear factor of kappa light polypeptide gene enhancer in NFKB1 Nuclear factor of kappa light polypeptide gene enhancer in NFKB1 Nuclear factor of kappa light polypeptide gene enhancer in NFKB1 Nuclear factor of kappa light polypeptide gene enhancer in NFKB1 Nuclear factor of kappa light polypeptide gene enhancer in NFKB1 Nuclear factor of kappa light polypeptide gene enhancer in NFKB1 Nuclear factor of kappa light polypeptide gene enhancer in NFKB1 Nuclear factor of kappa light polypeptide gene enhancer in NFKB1 Nuclear factor of kappa light polypeptide gene enhancer in NFKB1 Nuclear factor of kappa light polypeptide gene enhancer in NFKB1 Nuclear factor of kappa light polypeptide gene enhancer in NFKB1 Nuclear factor of kappa light polypeptide gene enhancer in NFKB1 Nuclear factor of kappa light polypeptide gene enhancer in NFKB1 Nuclear factor of kappa light polypeptide gene enhancer in NFKB1 Nuclear factor of kappa light polypeptide gene enhancer in NFKB1 Nuclear factor of kappa light polypeptide gene enhancer in NFKB1 Nuclear factor of kappa light polypeptide gene enhancer in NFKB1 Nuclear factor of kappa light polypeptide gene enhancer in NFKB1 Nuclear factor of kappa light polypeptide gene enhancer in NFKB1 Nuclear factor of kappa light polypeptide gene enhancer in NFKB1 Nuclear factor of kappa light polypeptide gene enhancer in NFKB1 Nuclear factor of kappa light polypeptide gene enhancer in NFKB1 Nuclear factor of kappa light polypeptide gene enhancer in NFKB1 Nuclear factor of kappa light polypeptide gene enhancer in NFKB1 Nuclear factor of kappa light polypeptide gene enhancer in NFKB1 Nuclear factor of kappa light polypeptide gene enhancer in NFKB1 Nuclear factor of kappa light polypeptide gene enhancer in NFKB1 Nuclear factor of kappa light polypeptide gene enhancer in NFKB1 Nuclear factor of kappa light polypeptide gene enhancer in NFKB1 Nuclear factor of kappa light polypeptide gene enhancer in NFKB1 Nuclear factor of kappa light polypeptide gene enhancer in NFKB1 Nuclear factor of kappa light polypeptide gene enhancer in NFKB1 Nuclear factor of kappa light polypeptide gene enhancer in NFKB1 Nuclear factor of kappa light polypeptide gene enhancer in

NFKB1 Nuclear factor of kappa light polypeptide gene enhancer in NFKB1 Nuclear factor of kappa light polypeptide gene enhancer in NFKB1 Nuclear factor of kappa light polypeptide gene enhancer in NFKB1 Nuclear factor of kappa light polypeptide gene enhancer in NFKB1 Nuclear factor of kappa light polypeptide gene enhancer in NFKB1 Nuclear factor of kappa light polypeptide gene enhancer in NFKB1 Nuclear factor of kappa light polypeptide gene enhancer in NFKB1 Nuclear factor of kappa light polypeptide gene enhancer in NFKB1 Nuclear factor of kappa light polypeptide gene enhancer in SLC25A4 Solute carrier family 25 (mitochondrial carrier; adenine nuSLC25A4 Solute carrier family 25 (mitochondrial carrier; adenine nuSLC25A4 Solute carrier family 25 (mitochondrial carrier; adenine nuSLC25A4 Solute carrier family 25 (mitochondrial carrier; adenine nuSLC25A4 Solute carrier family 25 (mitochondrial carrier; adenine nuSLC25A4 Solute carrier family 25 (mitochondrial carrier; adenine nuSLC25A4 Solute carrier family 25 (mitochondrial carrier; adenine nuSLC25A4 Solute carrier family 25 (mitochondrial carrier; adenine nuSLC25A4 Solute carrier family 25 (mitochondrial carrier; adenine nuSLC25A4 Solute carrier family 25 (mitochondrial carrier; adenine nuSLC25A4 Solute carrier family 25 (mitochondrial carrier; adenine nuSNAP25 Synaptosomal-associated protein, 25kDaSNAP25 Synaptosomal-associated protein, 25kDaSNAP25 Synaptosomal-associated protein, 25kDaSNAP25 Synaptosomal-associated protein, 25kDaSNAP25 Synaptosomal-associated protein, 25kDaSNAP25 Synaptosomal-associated protein, 25kDaSNAP25 Synaptosomal-associated protein, 25kDaSNAP25 Synaptosomal-associated protein, 25kDaSNAP25 Synaptosomal-associated protein, 25kDaTUBB Tubulin, beta class ITUBB Tubulin, beta class ITUBB Tubulin, beta class ITUBB Tubulin, beta class ITUBB Tubulin, beta class ITUBB Tubulin, beta class ITUBB Tubulin, beta class ITUBB Tubulin, beta class ITUBB Tubulin, beta class IPRKAA1 (AMProtein kinase, AMP-activated, alpha 1 catalytic subunitPRKAA1 (AMProtein kinase, AMP-activated, alpha 1 catalytic subunitPRKAA1 (AMProtein kinase, AMP-activated, alpha 1 catalytic subunitPRKAA1 (AMProtein kinase, AMP-activated, alpha 1 catalytic subunitPRKAA1 (AMProtein kinase, AMP-activated, alpha 1 catalytic subunitPRKAA1 (AMProtein kinase, AMP-activated, alpha 1 catalytic subunitPRKAA1 (AMProtein kinase, AMP-activated, alpha 1 catalytic subunitPRKAA1 (AMProtein kinase, AMP-activated, alpha 1 catalytic subunit

PRKAA1 (AMProtein kinase, AMP-activated, alpha 1 catalytic subunitPRKAA1 (AMProtein kinase, AMP-activated, alpha 1 catalytic subunitPRKAA1 (AMProtein kinase, AMP-activated, alpha 1 catalytic subunitPRKAA1 (AMProtein kinase, AMP-activated, alpha 1 catalytic subunitPRKAA1 (AMProtein kinase, AMP-activated, alpha 1 catalytic subunitPRKAA1 (AMProtein kinase, AMP-activated, alpha 1 catalytic subunitPRKAA1 (AMProtein kinase, AMP-activated, alpha 1 catalytic subunitPRKAA1 (AMProtein kinase, AMP-activated, alpha 1 catalytic subunitPRKAA1 (AMProtein kinase, AMP-activated, alpha 1 catalytic subunitPRKAA1 (AMProtein kinase, AMP-activated, alpha 1 catalytic subunitPRKAA1 (AMProtein kinase, AMP-activated, alpha 1 catalytic subunitPRKAA1 (AMProtein kinase, AMP-activated, alpha 1 catalytic subunitPRKAA1 (AMProtein kinase, AMP-activated, alpha 1 catalytic subunitPRKAA1 (AMProtein kinase, AMP-activated, alpha 1 catalytic subunitPRKAA1 (AMProtein kinase, AMP-activated, alpha 1 catalytic subunitPRKAA1 (AMProtein kinase, AMP-activated, alpha 1 catalytic subunitPRKAA1 (AMProtein kinase, AMP-activated, alpha 1 catalytic subunitPRKAA1 (AMProtein kinase, AMP-activated, alpha 1 catalytic subunitPRKAA1 (AMProtein kinase, AMP-activated, alpha 1 catalytic subunitPRKAA1 (AMProtein kinase, AMP-activated, alpha 1 catalytic subunitPRKAA1 (AMProtein kinase, AMP-activated, alpha 1 catalytic subunitPRKAA1 (AMProtein kinase, AMP-activated, alpha 1 catalytic subunitPRKAA1 (AMProtein kinase, AMP-activated, alpha 1 catalytic subunitPRKAA1 (AMProtein kinase, AMP-activated, alpha 1 catalytic subunitPRKAA1 (AMProtein kinase, AMP-activated, alpha 1 catalytic subunitPRKAA1 (AMProtein kinase, AMP-activated, alpha 1 catalytic subunitPRKAA1 (AMProtein kinase, AMP-activated, alpha 1 catalytic subunitPRKAA1 (AMProtein kinase, AMP-activated, alpha 1 catalytic subunitPRKAA1 (AMProtein kinase, AMP-activated, alpha 1 catalytic subunitPRKAA1 (AMProtein kinase, AMP-activated, alpha 1 catalytic subunitPRKAA1 (AMProtein kinase, AMP-activated, alpha 1 catalytic subunitPRKAA1 (AMProtein kinase, AMP-activated, alpha 1 catalytic subunitPRKAA1 (AMProtein kinase, AMP-activated, alpha 1 catalytic subunitPRKAA1 (AMProtein kinase, AMP-activated, alpha 1 catalytic subunitPRKAA1 (AMProtein kinase, AMP-activated, alpha 1 catalytic subunit

Supplementary Table S9A: Biological Processes and KEGG pathways connected with HD associated genes with TVS and targets of FDA approved drugs or potential targets o f drugsHD association No of GO ter (BP)Caudate down HTT, interacting protein 24Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Functinally related and observed/identified in separa 40

Caudate down HTT, interacting protein 36Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein

Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate UP, HTT interacting protein 74Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein

Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein

Caudate down HTT, interacting protein 15Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate UP, HTT interacting protein 96Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein

Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein

Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Co-expressGenefriends, Co-expressdb 4Co-expressGenefriends, Co-expressdb Co-expressGenefriends, Co-expressdb Co-expressGenefriends, Co-expressdb Caudate down, Hdsi, HTT interacting protein 15Caudate down, Hdsi, HTT interacting protein Caudate down, Hdsi, HTT interacting protein Caudate down, Hdsi, HTT interacting protein Caudate down, Hdsi, HTT interacting protein Caudate down, Hdsi, HTT interacting protein Caudate down, Hdsi, HTT interacting protein Caudate down, Hdsi, HTT interacting protein Caudate down, Hdsi, HTT interacting protein Caudate down, Hdsi, HTT interacting protein Caudate down, Hdsi, HTT interacting protein Caudate down, Hdsi, HTT interacting protein Caudate down, Hdsi, HTT interacting protein Caudate down, Hdsi, HTT interacting protein Caudate down, Hdsi, HTT interacting protein Caudate down, Hdsi, HTT interacting protein 14Caudate down, Hdsi, HTT interacting protein Caudate down, Hdsi, HTT interacting protein Caudate down, Hdsi, HTT interacting protein Caudate down, Hdsi, HTT interacting protein Caudate down, Hdsi, HTT interacting protein Caudate down, Hdsi, HTT interacting protein Caudate down, Hdsi, HTT interacting protein

Caudate down, Hdsi, HTT interacting protein Caudate down, Hdsi, HTT interacting protein Caudate down, Hdsi, HTT interacting protein Caudate down, Hdsi, HTT interacting protein Caudate down, Hdsi, HTT interacting protein Caudate down, Hdsi, HTT interacting protein HTT interacting proteins and has been shown functi 4HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related Caudate UP, Co-expressdb, HTT interacting protein 23Caudate UP, Co-expressdb, HTT interacting protein Caudate UP, Co-expressdb, HTT interacting protein Caudate UP, Co-expressdb, HTT interacting protein Caudate UP, Co-expressdb, HTT interacting protein Caudate UP, Co-expressdb, HTT interacting protein Caudate UP, Co-expressdb, HTT interacting protein Caudate UP, Co-expressdb, HTT interacting protein Caudate UP, Co-expressdb, HTT interacting protein Caudate UP, Co-expressdb, HTT interacting protein Caudate UP, Co-expressdb, HTT interacting protein Caudate UP, Co-expressdb, HTT interacting protein Caudate UP, Co-expressdb, HTT interacting protein Caudate UP, Co-expressdb, HTT interacting protein Caudate UP, Co-expressdb, HTT interacting protein Caudate UP, Co-expressdb, HTT interacting protein Caudate UP, Co-expressdb, HTT interacting protein Caudate UP, Co-expressdb, HTT interacting protein Caudate UP, Co-expressdb, HTT interacting protein Caudate UP, Co-expressdb, HTT interacting protein Caudate UP, Co-expressdb, HTT interacting protein Caudate UP, Co-expressdb, HTT interacting protein Caudate UP, Co-expressdb, HTT interacting protein Caudate UP, Co-expressdb, HTT interacting protein Caudate UP, Co-expressdb, HTT interacting protein Caudate UP, HDsi 7Caudate UP, HDsi Caudate UP, HDsi Caudate UP, HDsi Caudate UP, HDsi Caudate UP, HDsi Caudate UP, HDsi Caudate down HTT, interacting protein 15Caudate down HTT, interacting protein

Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate UP, Co-expressdb, HTT interacting protein 17Caudate UP, Co-expressdb, HTT interacting protein Caudate UP, Co-expressdb, HTT interacting protein Caudate UP, Co-expressdb, HTT interacting protein Caudate UP, Co-expressdb, HTT interacting protein Caudate UP, Co-expressdb, HTT interacting protein Caudate UP, Co-expressdb, HTT interacting protein Caudate UP, Co-expressdb, HTT interacting protein Caudate UP, Co-expressdb, HTT interacting protein Caudate UP, Co-expressdb, HTT interacting protein Caudate UP, Co-expressdb, HTT interacting protein Caudate UP, Co-expressdb, HTT interacting protein Caudate UP, Co-expressdb, HTT interacting protein Caudate UP, Co-expressdb, HTT interacting protein Caudate UP, Co-expressdb, HTT interacting protein Caudate UP, Co-expressdb, HTT interacting protein Caudate UP, Co-expressdb, HTT interacting protein HTT interacting proteins and has been shown functi 102HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related

HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related

HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functi 37HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related

HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related HTT interacting proteins and has been shown functionally related Caudate UP, HTT interacting protein 26Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein

Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate UP, HTT interacting protein Caudate down, AAO 56Caudate down, AAOCaudate down, AAOCaudate down, AAOCaudate down, AAOCaudate down, AAOCaudate down, AAOCaudate down, AAOCaudate down, AAOCaudate down, AAOCaudate down, AAOCaudate down, AAOCaudate down, AAOCaudate down, AAOCaudate down, AAOCaudate down, AAOCaudate down, AAOCaudate down, AAOCaudate down, AAOCaudate down, AAOCaudate down, AAOCaudate down, AAOCaudate down, AAOCaudate down, AAOCaudate down, AAOCaudate down, AAOCaudate down, AAOCaudate down, AAOCaudate down, AAOCaudate down, AAOCaudate down, AAOCaudate down, AAOCaudate down, AAOCaudate down, AAOCaudate down, AAO

Caudate down, AAOCaudate down, AAOCaudate down, AAOCaudate down, AAOCaudate down, AAOCaudate down, AAOCaudate down, AAOCaudate down, AAOCaudate down, AAOCaudate down, AAOCaudate down, AAOCaudate down, AAOCaudate down, AAOCaudate down, AAOCaudate down, AAOCaudate down, AAOCaudate down, AAOCaudate down, AAOCaudate down, AAOCaudate down, AAOCaudate down, AAOCaudate down HTT, interacting protein 19Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate UP, Co-expressGenefriends 138Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends

Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends

Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends Caudate UP, Co-expressGenefriends AO, Caudate down 36AO, Caudate down AO, Caudate down AO, Caudate down AO, Caudate down AO, Caudate down

AO, Caudate down AO, Caudate down AO, Caudate down AO, Caudate down AO, Caudate down AO, Caudate down AO, Caudate down AO, Caudate down AO, Caudate down AO, Caudate down AO, Caudate down AO, Caudate down AO, Caudate down AO, Caudate down AO, Caudate down AO, Caudate down AO, Caudate down AO, Caudate down AO, Caudate down AO, Caudate down AO, Caudate down AO, Caudate down AO, Caudate down AO, Caudate down AO, Caudate down AO, Caudate down AO, Caudate down AO, Caudate down AO, Caudate down AO, Caudate down Functinally related and observed/identified in separa 55Functinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cate

Functinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateCaudate down, HDsi 54Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi

Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi

Caudate down, HDsi AO, Caudate down, HDsi 30AO, Caudate down, HDsi AO, Caudate down, HDsi AO, Caudate down, HDsi AO, Caudate down, HDsi AO, Caudate down, HDsi AO, Caudate down, HDsi AO, Caudate down, HDsi AO, Caudate down, HDsi AO, Caudate down, HDsi AO, Caudate down, HDsi AO, Caudate down, HDsi AO, Caudate down, HDsi AO, Caudate down, HDsi AO, Caudate down, HDsi AO, Caudate down, HDsi AO, Caudate down, HDsi AO, Caudate down, HDsi AO, Caudate down, HDsi AO, Caudate down, HDsi AO, Caudate down, HDsi AO, Caudate down, HDsi AO, Caudate down, HDsi AO, Caudate down, HDsi AO, Caudate down, HDsi AO, Caudate down, HDsi AO, Caudate down, HDsi AO, Caudate down, HDsi AO, Caudate down, HDsi AO, Caudate down, HDsi Functinally related and observed/identified in separa 31Functinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cate

Functinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateCaudate down, HDsi 37Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi

Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Caudate down, HDsi Functinally related and observed/identified in separa 17Functinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateFunctinally related and observed/identified in separate experiment to be in other cateCaudate down, HDsi 70Caudate down, HDsi 70Caudate down, HDsi 70Caudate down, HDsi 70Caudate down, HDsi 70Caudate down, HDsi 70Caudate down, HDsi 70Caudate down, HDsi 70Caudate down, HDsi 70Caudate down, HDsi 70Caudate down, HDsi 70Caudate down, HDsi 70Caudate down, HDsi 70Caudate down, HDsi 70Caudate down, HDsi 70Caudate down, HDsi 70Caudate down, HDsi 70Caudate down, HDsi 70Caudate down, HDsi 70Caudate down, HDsi 70Caudate down, HDsi 70Caudate down, HDsi 70

Caudate down, HDsi 70Caudate down, HDsi 70Caudate down, HDsi 70Caudate down, HDsi 70Caudate down, HDsi 70Caudate down, HDsi 70Caudate down, HDsi 70Caudate down, HDsi 70Caudate down, HDsi 70Caudate down, HDsi 70Caudate down, HDsi 70Caudate down, HDsi 70Caudate down, HDsi 70Caudate down, HDsi 70Caudate down, HDsi 70Caudate down, HDsi 70Caudate down, HDsi 70Caudate down, HDsi 70Caudate down, HDsi 70Caudate down, HDsi 70Caudate down, HDsi 70Caudate down, HDsi 70Caudate down, HDsi 70Caudate down, HDsi 70Caudate down, HDsi 70Caudate down, HDsi 70Caudate down, HDsi 70Caudate down, HDsi 70Caudate down, HDsi 70Caudate down, HDsi 70Caudate down, HDsi 70Caudate down, HDsi 70Caudate down, HDsi 70Caudate down, HDsi 70Caudate down, HDsi 70Caudate down, HDsi 70Caudate down, HDsi 70Caudate down, HDsi 70Caudate down, HDsi 70Caudate down, HDsi 70Caudate down, HDsi 70Caudate down, HDsi 70Caudate down, HDsi 70Caudate down, HDsi 70Caudate down, HDsi 70Caudate down, HDsi 70

Caudate down, HDsi 70Caudate down, HDsi 70Caudate down, HDsi 70Co-expressGenefriends, HTT interacting protein 44Co-expressGenefriends, HTT interacting protein Co-expressGenefriends, HTT interacting protein Co-expressGenefriends, HTT interacting protein Co-expressGenefriends, HTT interacting protein Co-expressGenefriends, HTT interacting protein Co-expressGenefriends, HTT interacting protein Co-expressGenefriends, HTT interacting protein Co-expressGenefriends, HTT interacting protein Co-expressGenefriends, HTT interacting protein Co-expressGenefriends, HTT interacting protein Co-expressGenefriends, HTT interacting protein Co-expressGenefriends, HTT interacting protein Co-expressGenefriends, HTT interacting protein Co-expressGenefriends, HTT interacting protein Co-expressGenefriends, HTT interacting protein Co-expressGenefriends, HTT interacting protein Co-expressGenefriends, HTT interacting protein Co-expressGenefriends, HTT interacting protein Co-expressGenefriends, HTT interacting protein Co-expressGenefriends, HTT interacting protein Co-expressGenefriends, HTT interacting protein Co-expressGenefriends, HTT interacting protein Co-expressGenefriends, HTT interacting protein Co-expressGenefriends, HTT interacting protein Co-expressGenefriends, HTT interacting protein Co-expressGenefriends, HTT interacting protein Co-expressGenefriends, HTT interacting protein Co-expressGenefriends, HTT interacting protein Co-expressGenefriends, HTT interacting protein Co-expressGenefriends, HTT interacting protein Co-expressGenefriends, HTT interacting protein Co-expressGenefriends, HTT interacting protein Co-expressGenefriends, HTT interacting protein Co-expressGenefriends, HTT interacting protein Co-expressGenefriends, HTT interacting protein Co-expressGenefriends, HTT interacting protein Co-expressGenefriends, HTT interacting protein Co-expressGenefriends, HTT interacting protein Co-expressGenefriends, HTT interacting protein Co-expressGenefriends, HTT interacting protein Co-expressGenefriends, HTT interacting protein Co-expressGenefriends, HTT interacting protein

Co-expressGenefriends, HTT interacting protein Co-expressGenefriends, HTT interacting protein Co-expressGenefriends, HTT interacting protein Co-expressGenefriends, HTT interacting protein Co-expressGenefriends, HTT interacting protein Co-expressGenefriends, HTT interacting protein Co-expressGenefriends, HTT interacting protein Co-expressGenefriends, HTT interacting protein Co-expressGenefriends, HTT interacting protein Caudate down, Hdsi, HTT interacting protein 11Caudate down, Hdsi, HTT interacting protein Caudate down, Hdsi, HTT interacting protein Caudate down, Hdsi, HTT interacting protein Caudate down, Hdsi, HTT interacting protein Caudate down, Hdsi, HTT interacting protein Caudate down, Hdsi, HTT interacting protein Caudate down, Hdsi, HTT interacting protein Caudate down, Hdsi, HTT interacting protein Caudate down, Hdsi, HTT interacting protein Caudate down, Hdsi, HTT interacting protein Caudate down, Hdsi, HTT interacting protein 9Caudate down, Hdsi, HTT interacting protein Caudate down, Hdsi, HTT interacting protein Caudate down, Hdsi, HTT interacting protein Caudate down, Hdsi, HTT interacting protein Caudate down, Hdsi, HTT interacting protein Caudate down, Hdsi, HTT interacting protein Caudate down, Hdsi, HTT interacting protein Caudate down, Hdsi, HTT interacting protein Caudate down HTT, interacting protein 9Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Caudate down HTT, interacting protein Functinally related but not obsereved in any one of t 43

Supplementary Table S9A: Biological Processes and KEGG pathways connected with HD associated genes with TVS and targets of FDA approved drugs or potential targets o f drugsGO Id GO term descriptionGO:0001666 response to hypoxiaGO:0001666 response to hypoxiaGO:0006112 energy reserve metabolic processGO:0006811 ion transportGO:0006816 calcium ion transportGO:0007165 signal transductionGO:0007173 epidermal growth factor receptor signaling pathwayGO:0007202 activation of phospholipase C activityGO:0007596 blood coagulationGO:0008543 fibroblast growth factor receptor signaling pathwayGO:0009791 post-embryonic developmentGO:0030168 platelet activationGO:0032469 endoplasmic reticulum calcium ion homeostasisGO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosisGO:0044281 small molecule metabolic processGO:0045087 innate immune responseGO:0048011 neurotrophin TRK receptor signaling pathwayGO:0048016 inositol phosphate-mediated signalingGO:0050796 regulation of insulin secretionGO:0050882 voluntary musculoskeletal movementGO:0051209 release of sequestered calcium ion into cytosolGO:0055085 transmembrane transportGO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum sGO:0070588 calcium ion transmembrane transport

GO:0000075GO:0000077 DNA damage checkpointGO:0000723 telomere maintenanceGO:0000724 double-strand break repair via homologous recombinationGO:0001666 response to hypoxiaGO:0001756 somitogenesisGO:0002331 pre-B cell allelic exclusionGO:0006281 DNA repairGO:0006302 double-strand break repairGO:0006468 protein phosphorylationGO:0006915 apoptotic processGO:0006974 response to DNA damage stimulusGO:0006975 DNA damage induced protein phosphorylationGO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

GO:0007050 cell cycle arrestGO:0007094 mitotic spindle assembly checkpointGO:0007131 reciprocal meiotic recombinationGO:0007165 signal transductionGO:0007292 female gamete generationGO:0007420 brain developmentGO:0007507 heart developmentGO:0008630 intrinsic apoptotic signaling pathway in response to DNA damageGO:0010212 response to ionizing radiationGO:0016572 histone phosphorylationGO:0018105 peptidyl-serine phosphorylationGO:0030889 negative regulation of B cell proliferationGO:0031572 G2 DNA damage checkpointGO:0035404 histone-serine phosphorylationGO:0036092 phosphatidylinositol-3-phosphate biosynthetic processGO:0042159 lipoprotein catabolic processGO:0043065 positive regulation of apoptotic processGO:0043066 negative regulation of apoptotic processGO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediatorGO:0043525 positive regulation of neuron apoptotic processGO:0046777 protein autophosphorylationGO:0051402 neuron apoptotic processGO:0051726 regulation of cell cycleGO:0071044 histone mRNA catabolic processGO:0071480 cellular response to gamma radiationGO:0090399 replicative senescence

GO:0001975 response to amphetamineGO:0002027 regulation of heart rateGO:0002576 platelet degranulationGO:0005513 detection of calcium ionGO:0005975 carbohydrate metabolic processGO:0005980 glycogen catabolic processGO:0006006 glucose metabolic processGO:0006936 muscle contractionGO:0007165 signal transductionGO:0007173 epidermal growth factor receptor signaling pathwayGO:0007186 G-protein coupled receptor signaling pathwayGO:0007202 activation of phospholipase C activityGO:0007268 synaptic transmissionGO:0007596 blood coagulationGO:0008543 fibroblast growth factor receptor signaling pathwayGO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmiGO:0010881 regulation of cardiac muscle contraction by regulation of the release of sequGO:0016044 cellular membrane organization

GO:0030168 platelet activationGO:0030801 positive regulation of cyclic nucleotide metabolic processGO:0032465 regulation of cytokinesisGO:0032516 positive regulation of phosphoprotein phosphatase activityGO:0035307 positive regulation of protein dephosphorylationGO:0043647 inositol phosphate metabolic processGO:0044281 small molecule metabolic processGO:0045087 innate immune responseGO:0046209 nitric oxide metabolic processGO:0048011 neurotrophin TRK receptor signaling pathwayGO:0050999 regulation of nitric-oxide synthase activityGO:0051343 positive regulation of cyclic-nucleotide phosphodiesterase activityGO:0051412 response to corticosterone stimulusGO:0051592 response to calcium ionGO:0055117 regulation of cardiac muscle contractionGO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activityGO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activityGO:1901844 regulation of cell communication by electrical coupling involved in cardiac conductionGO:0000122 negative regulation of transcription from RNAGO:0000165 MAPK cascadeGO:0000188 inactivation of MAPK activityGO:0001525 angiogenesisGO:0001570 vasculogenesisGO:0001666 response to hypoxiaGO:0001937 negative regulation of endothelial cell proliferationGO:0001960 negative regulation of cytokine-mediated signaling pathwayGO:0002026 regulation of the force of heart contractionGO:0002931 response to ischemiaGO:0003057 regulation of the force of heart contraction by chemical signalGO:0006641 triglyceride metabolic processGO:0006816 calcium ion transportGO:0006874 cellular calcium ion homeostasisGO:0006940 regulation of smooth muscle contractionGO:0007519 skeletal muscle tissue developmentGO:0007595 lactationGO:0007596 blood coagulationGO:0008104 protein localizationGO:0008285 negative regulation of cell proliferationGO:0009267 cellular response to starvationGO:0009968 negative regulation of signal transductionGO:0010524 positive regulation of calcium ion transport into cytosolGO:0010952 positive regulation of peptidase activityGO:0016050 vesicle organizationGO:0019048 virus-host interactionGO:0019217 regulation of fatty acid metabolic processGO:0019915 lipid storage

GO:0030193 regulation of blood coagulationGO:0030301 cholesterol transportGO:0030514 negative regulation of BMP signaling pathwayGO:0030857 negative regulation of epithelial cell differentiationGO:0030879 mammary gland developmentGO:0031295 T cell costimulationGO:0031397 negative regulation of protein ubiquitinationGO:0032091 negative regulation of protein bindingGO:0032507 maintenance of protein location in cellGO:0032570 response to progesterone stimulusGO:0033137 negative regulation of peptidyl-serine phosphorylationGO:0033138 positive regulation of peptidyl-serine phosphorylationGO:0033484 nitric oxide homeostasisGO:0042310 vasoconstrictionGO:0042524 negative regulation of tyrosine phosphorylation of Stat5 proteinGO:0042632 cholesterol homeostasisGO:0043407 negative regulation of MAP kinase activityGO:0043409 negative regulation of MAPK cascadeGO:0043627 response to estrogen stimulusGO:0044281 small molecule metabolic processGO:0045019 negative regulation of nitric oxide biosynthetic processGO:0045907 positive regulation of vasoconstrictionGO:0046209 nitric oxide metabolic processGO:0046426 negative regulation of JAK-STAT cascadeGO:0048554 positive regulation of metalloenzyme activityGO:0050900 leukocyte migrationGO:0050999 regulation of nitric-oxide synthase activityGO:0051001 negative regulation of nitric-oxide synthase activityGO:0051259 protein oligomerizationGO:0051260 protein homooligomerizationGO:0051480 cytosolic calcium ion homeostasisGO:0051592 response to calcium ionGO:0051899 membrane depolarizationGO:0052547 regulation of peptidase activityGO:0055074 calcium ion homeostasisGO:0060056 mammary gland involutionGO:0070836 caveola assemblyGO:0071455 cellular response to hyperoxiaGO:0072584 caveolin-mediated endocytosisGO:0090090 negative regulation of canonical Wnt receptor signaling pathwayGO:0090263 positive regulation of canonical Wnt receptor signaling pathwayGO:0097190 apoptotic signaling pathwayGO:2000286 receptor internalization involved in canonical Wnt receptor signaling pathwayGO:2000811 negative regulation of anoikisGO:2001238 positive regulation of extrinsic apoptotic signaling pathwayGO:2001244 positive regulation of intrinsic apoptotic signaling pathway

GO:0006090 pyruvate metabolic processGO:0006099 tricarboxylic acid cycleGO:0006120 mitochondrial electron transport, NADH to ubiquinoneGO:0006508 proteolysisGO:0006554 lysine catabolic processGO:0007369 gastrulationGO:0008033 tRNA processingGO:0009083 branched-chain amino acid catabolic processGO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvateGO:0034641 cellular nitrogen compound metabolic processGO:0042391 regulation of membrane potentialGO:0044281 small molecule metabolic processGO:0045454 cell redox homeostasisGO:0048240 sperm capacitationGO:0055114 oxidation-reduction processGO:0000060 protein import into nucleus, translocationGO:0000075 cell cycle checkpointGO:0000122 negative regulation of transcription from RNA polymerase II promoterGO:0000733 DNA strand renaturationGO:0001701 in utero embryonic developmentGO:0001756 somitogenesisGO:0001836 release of cytochrome c from mitochondriaGO:0002309 T cell proliferation involved in immune responseGO:0002326 B cell lineage commitmentGO:0002360 T cell lineage commitmentGO:0002931 response to ischemiaGO:0006284 base-excision repairGO:0006289 nucleotide-excision repairGO:0006302 double-strand break repairGO:0006351 transcription, DNA-dependentGO:0006355 regulation of transcription, DNA-dependentGO:0006461 protein complex assemblyGO:0006915 apoptotic processGO:0006917 induction of apoptosisGO:0006974 response to DNA damage stimulusGO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting inGO:0006979 response to oxidative stressGO:0006983 ER overload responseGO:0007049 cell cycleGO:0007050 cell cycle arrestGO:0007179 transforming growth factor beta receptor signaling pathwayGO:0007265 Ras protein signal transductionGO:0007275 multicellular organismal developmentGO:0007369 gastrulationGO:0007406 negative regulation of neuroblast proliferation

GO:0007417 central nervous system developmentGO:0007569 cell agingGO:0007596 blood coagulationGO:0008104 protein localizationGO:0008156 negative regulation of DNA replicationGO:0008283 cell proliferationGO:0008285 negative regulation of cell proliferationGO:0008340 determination of adult lifespanGO:0009303 rRNA transcriptionGO:0009411 response to UVGO:0009651 response to salt stressGO:0009792 embryo development ending in birth or egg hatchingGO:0010165 response to X-rayGO:0010332 response to gamma radiationGO:0010666 positive regulation of cardiac muscle cell apoptotic processGO:0019048 virus-host interactionGO:0030154 cell differentiationGO:0030308 negative regulation of cell growthGO:0030330 DNA damage response, signal transduction by p53 class mediatorGO:0030512 negative regulation of transforming growth factor beta receptor signaling pathwayGO:0031065 positive regulation of histone deacetylationGO:0031571 mitotic G1 DNA damage checkpointGO:0032461 positive regulation of protein oligomerizationGO:0033077 T cell differentiation in thymusGO:0034103 regulation of tissue remodelingGO:0034613 cellular protein localizationGO:0034644 cellular response to UVGO:0035264 multicellular organism growthGO:0035690 cellular response to drugGO:0042127 regulation of cell proliferationGO:0042149 cellular response to glucose starvationGO:0042493 response to drugGO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediatorGO:0042981 regulation of apoptotic processGO:0043065 positive regulation of apoptotic processGO:0043066 negative regulation of apoptotic processGO:0043523 regulation of neuron apoptotic processGO:0043525 positive regulation of neuron apoptotic processGO:0045892 negative regulation of transcription, DNA-dependentGO:0045893 positive regulation of transcription, DNA-dependentGO:0045944 positive regulation of transcription from RNA polymerase II promoterGO:0046677 response to antibioticGO:0046902 regulation of mitochondrial membrane permeabilityGO:0048147 negative regulation of fibroblast proliferationGO:0050731 positive regulation of peptidyl-tyrosine phosphorylationGO:0051097 negative regulation of helicase activity

GO:0051262 protein tetramerizationGO:0051276 chromosome organizationGO:0051402 neuron apoptotic processGO:0051726 regulation of cell cycleGO:0070245 positive regulation of thymocyte apoptotic processGO:0071158 positive regulation of cell cycle arrestGO:0071456 cellular response to hypoxiaGO:0071479 cellular response to ionizing radiationGO:0071850 mitotic cell cycle arrestGO:0072332 intrinsic apoptotic signaling pathway by p53 class mediatorGO:0090200 positive regulation of release of cytochrome c from mitochondriaGO:0090343 positive regulation of cell agingGO:0090399 replicative senescenceGO:0090403 oxidative stress-induced premature senescenceGO:0097193 intrinsic apoptotic signaling pathwayGO:1901525 negative regulation of macromitophagyGO:2000378 negative regulation of reactive oxygen species metabolic processGO:2000379 positive regulation of reactive oxygen species metabolic processGO:2001244 positive regulation of intrinsic apoptotic signaling pathwayGO:0000354 cis assembly of pre-catalytic spliceosomeGO:0000398 mRNA splicing, via spliceosomeGO:0008380 RNA splicingGO:0010467 gene expressionGO:0001956 positive regulation of neurotransmitter secretiGO:0006112 energy reserve metabolic processGO:0006886 intracellular protein transportGO:0007268 synaptic transmissionGO:0007269 neurotransmitter secretionGO:0009629 response to gravityGO:0014047 glutamate secretionGO:0016081 synaptic vesicle docking involved in exocytosisGO:0016192 vesicle-mediated transportGO:0017156 calcium ion-dependent exocytosisGO:0017157 regulation of exocytosisGO:0044267 cellular protein metabolic processGO:0044281 small molecule metabolic processGO:0045921 positive regulation of exocytosisGO:0050796 regulation of insulin secretionGO:0001525 angiogenesisGO:0005975 carbohydrate metabolic processGO:0006006 glucose metabolic processGO:0006094 gluconeogenesisGO:0006096 glycolysisGO:0006959 humoral immune responseGO:0007599 hemostasisGO:0007611 learning or memory

GO:0019242 methylglyoxal biosynthetic processGO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apopGO:0043524 negative regulation of neuron apoptotic processGO:0044281 small molecule metabolic processGO:0046185 aldehyde catabolic processGO:0051156 glucose 6-phosphate metabolic processGO:0006120 mitochondrial electron transport, NADH to ubGO:0022904 respiratory electron transport chainGO:0044281 small molecule metabolic processGO:0055114 oxidation-reduction process

GO:0000122 negative regulation of transcription from RNAGO:0001666 response to hypoxiaGO:0006355 regulation of transcription, DNA-dependentGO:0006367 transcription initiation from RNA polymerase II promoterGO:0006461 protein complex assemblyGO:0007165 signal transductionGO:0007219 Notch signaling pathwayGO:0008589 regulation of smoothened signaling pathwayGO:0010467 gene expressionGO:0016573 histone acetylationGO:0018076 N-terminal peptidyl-lysine acetylationGO:0019048 virus-host interactionGO:0030718 germ-line stem cell maintenanceGO:0033554 cellular response to stressGO:0042592 homeostatic processGO:0042733 embryonic digit morphogenesisGO:0044255 cellular lipid metabolic processGO:0044281 small molecule metabolic processGO:0045087 innate immune responseGO:0045893 positive regulation of transcription, DNA-dependentGO:0045944 positive regulation of transcription from RNA polymerase II promoterGO:0061418 regulation of transcription from RNA polymerase II promoter in response to GO:0071456 cellular response to hypoxia

GO:0000045 autophagic vacuole assemblyGO:0006508 proteolysisGO:0008219 cell deathGO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC clGO:0022617 extracellular matrix disassemblyGO:0030198 extracellular matrix organizationGO:0030574 collagen catabolic processGO:0000266 mitochondrial fissionGO:0003374 dynamin polymerization involved in mitochondrial fission

GO:0006915 apoptotic processGO:0006921 cellular component disassembly involved in execution phase of apoptosisGO:0010821 regulation of mitochondrion organizationGO:0016559 peroxisome fissionGO:0043653 mitochondrial fragmentation involved in apoptotic processGO:0050714 positive regulation of protein secretionGO:0051289 protein homotetramerizationGO:0070584 mitochondrion morphogenesisGO:0090141 positive regulation of mitochondrial fissionGO:0090149 membrane fission involved in mitochondrial fissionGO:0090200 positive regulation of release of cytochrome c from mitochondriaGO:1900063 regulation of peroxisome organizationGO:2001244 positive regulation of intrinsic apoptotic signaling pathwayGO:0000086 G2/M transition of mitotic cell cycleGO:0006184 GTP catabolic processGO:0006355 regulation of transcription, DNA-dependentGO:0006892 post-Golgi vesicle-mediated transportGO:0006897 endocytosisGO:0006898 receptor-mediated endocytosisGO:0007165 signal transductionGO:0016044 cellular membrane organizationGO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class IIGO:0031623 receptor internalizationGO:0033572 transferrin transportGO:0043065 positive regulation of apoptotic processGO:0044281 small molecule metabolic processGO:0045893 positive regulation of transcription, DNA-dependentGO:0046209 nitric oxide metabolic processGO:0048489 synaptic vesicle transportGO:0050999 regulation of nitric-oxide synthase activityGO:0000060 protein import into nucleus, translocationGO:0001649 osteoblast differentiationGO:0001893 maternal placenta developmentGO:0001934 positive regulation of protein phosphorylationGO:0005977 glycogen metabolic processGO:0005978 glycogen biosynthetic processGO:0005979 regulation of glycogen biosynthetic processGO:0006006 glucose metabolic processGO:0006412 translationGO:0006417 regulation of translationGO:0006464 cellular protein modification processGO:0006468 protein phosphorylationGO:0006469 negative regulation of protein kinase activityGO:0006809 nitric oxide biosynthetic processGO:0006915 apoptotic processGO:0006924 activation-induced cell death of T cells

GO:0006954 inflammatory responseGO:0007165 signal transductionGO:0007173 epidermal growth factor receptor signaling pathwayGO:0007186 G-protein coupled receptor signaling pathwayGO:0007281 germ cell developmentGO:0007568 agingGO:0007596 blood coagulationGO:0008283 cell proliferationGO:0008286 insulin receptor signaling pathwayGO:0008543 fibroblast growth factor receptor signaling pathwayGO:0008637 apoptotic mitochondrial changesGO:0009408 response to heatGO:0009725 response to hormone stimulusGO:0010467 gene expressionGO:0010507 negative regulation of autophagyGO:0010748 negative regulation of plasma membrane long-chain fatty acid transportGO:0010765 positive regulation of sodium ion transportGO:0010907 positive regulation of glucose metabolic processGO:0010951 negative regulation of endopeptidase activityGO:0010975 regulation of neuron projection developmentGO:0015758 glucose transportGO:0016044 cellular membrane organizationGO:0016070 RNA metabolic processGO:0016071 mRNA metabolic processGO:0016310 phosphorylationGO:0016567 protein ubiquitinationGO:0018105 peptidyl-serine phosphorylationGO:0030030 cell projection organizationGO:0030154 cell differentiationGO:0030163 protein catabolic processGO:0030168 platelet activationGO:0030307 positive regulation of cell growthGO:0030334 regulation of cell migrationGO:0031018 endocrine pancreas developmentGO:0031295 T cell costimulationGO:0031659 positive regulation of cyclin-dependent protein serine/threonine kinase activGO:0031999 negative regulation of fatty acid beta-oxidationGO:0032094 response to foodGO:0032270 positive regulation of cellular protein metabolic processGO:0032287 peripheral nervous system myelin maintenanceGO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic prGO:0032869 cellular response to insulin stimulusGO:0032880 regulation of protein localizationGO:0033138 positive regulation of peptidyl-serine phosphorylationGO:0034405 response to fluid shear stressGO:0035556 intracellular signal transduction

GO:0042593 glucose homeostasisGO:0042640 anagenGO:0043065 positive regulation of apoptotic processGO:0043066 negative regulation of apoptotic processGO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apopGO:0043491 protein kinase B signaling cascadeGO:0043536 positive regulation of blood vessel endothelial cell migrationGO:0044281 small molecule metabolic processGO:0045087 innate immune responseGO:0045429 positive regulation of nitric oxide biosynthetic processGO:0045600 positive regulation of fat cell differentiationGO:0045725 positive regulation of glycogen biosynthetic processGO:0045792 negative regulation of cell sizeGO:0045861 negative regulation of proteolysisGO:0045907 positive regulation of vasoconstrictionGO:0045944 positive regulation of transcription from RNA polymerase II promoterGO:0046209 nitric oxide metabolic processGO:0046326 positive regulation of glucose importGO:0046329 negative regulation of JNK cascadeGO:0046777 protein autophosphorylationGO:0046889 positive regulation of lipid biosynthetic processGO:0048009 insulin-like growth factor receptor signaling pathwayGO:0048011 neurotrophin TRK receptor signaling pathwayGO:0048015 phosphatidylinositol-mediated signalingGO:0050999 regulation of nitric-oxide synthase activityGO:0051000 positive regulation of nitric-oxide synthase activityGO:0051091 positive regulation of sequence-specific DNA binding transcription factor activityGO:0051146 striated muscle cell differentiationGO:0060644 mammary gland epithelial cell differentiationGO:0060709 glycogen cell differentiation involved in embryonic placenta developmentGO:0060716 labyrinthine layer blood vessel developmentGO:0070141 response to UV-AGO:0071363 cellular response to growth factor stimulusGO:0071364 cellular response to epidermal growth factor stimulusGO:0071456 cellular response to hypoxiaGO:0090004 positive regulation of establishment of protein localization to plasma membraneGO:0090201 negative regulation of release of cytochrome c from mitochondriaGO:0097193 intrinsic apoptotic signaling pathwayGO:1900740 positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathwayGO:1901976 regulation of cell cycle checkpointGO:0001525 angiogenesisGO:0001841 neural tube formationGO:0002224 toll-like receptor signaling pathwayGO:0002756 MyD88-independent toll-like receptor signaling pathwayGO:0006508 proteolysisGO:0006915 apoptotic process

GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic procGO:0006921 cellular component disassembly involved in execution phase of apoptosisGO:0007507 heart developmentGO:0009409 response to coldGO:0019048 virus-host interactionGO:0030225 macrophage differentiationGO:0032025 response to cobalt ionGO:0032355 response to estradiol stimulusGO:0032496 response to lipopolysaccharideGO:0034138 toll-like receptor 3 signaling pathwayGO:0034142 toll-like receptor 4 signaling pathwayGO:0034612 response to tumor necrosis factorGO:0035666 TRIF-dependent toll-like receptor signaling pathwayGO:0035872 nucleotide-binding domain, leucine rich repeat containing receptor signaling pathwayGO:0042981 regulation of apoptotic processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB cascadeGO:0043124 negative regulation of I-kappaB kinase/NF-kappaB cascadeGO:0045087 innate immune responseGO:0045471 response to ethanolGO:0045651 positive regulation of macrophage differentiationGO:0045862 positive regulation of proteolysisGO:0046677 response to antibioticGO:0051291 protein heterooligomerizationGO:0051603 proteolysis involved in cellular protein catabolic processGO:0070423 nucleotide-binding oligomerization domain containing signaling pathwayGO:0071260 cellular response to mechanical stimulusGO:0097190 apoptotic signaling pathwayGO:0097191 extrinsic apoptotic signaling pathwayGO:0097193 intrinsic apoptotic signaling pathwayGO:0097202 activation of cysteine-type endopeptidase activityGO:1900740 positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathwayGO:0000096 sulfur amino acid metabolic processGO:0001958 endochondral ossificationGO:0001974 blood vessel remodelingGO:0006535 cysteine biosynthetic process from serineGO:0006563 L-serine metabolic processGO:0006565 L-serine catabolic processGO:0006801 superoxide metabolic processGO:0019343 cysteine biosynthetic process via cystathionineGO:0019344 cysteine biosynthetic processGO:0019346 transsulfurationGO:0019448 L-cysteine catabolic processGO:0021587 cerebellum morphogenesisGO:0030823 regulation of cGMP metabolic processGO:0031667 response to nutrient levelsGO:0034641 cellular nitrogen compound metabolic process

GO:0043066 negative regulation of apoptotic processGO:0043418 homocysteine catabolic processGO:0043506 regulation of JUN kinase activityGO:0044281 small molecule metabolic processGO:0050667 homocysteine metabolic processGO:0050880 regulation of blood vessel sizeGO:0051593 response to folic acidGO:0060135 maternal process involved in female pregnancyGO:0060351 cartilage development involved in endochondral bone morphogenesisGO:0070814 hydrogen sulfide biosynthetic processGO:0071456 cellular response to hypoxiaGO:0001963 synaptic transmission, dopaminergicGO:0001973 adenosine receptor signaling pathwayGO:0001975 response to amphetamineGO:0006171 cAMP biosynthetic processGO:0006355 regulation of transcription, DNA-dependentGO:0006469 negative regulation of protein kinase activityGO:0006909 phagocytosisGO:0006915 apoptotic processGO:0006954 inflammatory responseGO:0006968 cellular defense responseGO:0007169 transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007186 G-protein coupled receptor signaling pathwayGO:0007188 adenylate cyclase-modulating G-protein coupled receptor signaling pathwayGO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathwayGO:0007190 activation of adenylate cyclase activityGO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathwayGO:0007267 cell-cell signalingGO:0007271 synaptic transmission, cholinergicGO:0007417 central nervous system developmentGO:0007596 blood coagulationGO:0007600 sensory perceptionGO:0007626 locomotory behaviorGO:0008015 blood circulationGO:0008285 negative regulation of cell proliferationGO:0014049 positive regulation of glutamate secretionGO:0014057 positive regulation of acetylcholine secretionGO:0014061 regulation of norepinephrine secretionGO:0030819 positive regulation of cAMP biosynthetic processGO:0031000 response to caffeineGO:0032230 positive regulation of synaptic transmission, GABAergicGO:0035249 synaptic transmission, glutamatergicGO:0035810 positive regulation of urine volumeGO:0035815 positive regulation of renal sodium excretionGO:0040013 negative regulation of locomotionGO:0042311 vasodilation

GO:0042493 response to drugGO:0042755 eating behaviorGO:0043116 negative regulation of vascular permeabilityGO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic processGO:0043279 response to alkaloidGO:0043524 negative regulation of neuron apoptotic processGO:0046636 negative regulation of alpha-beta T cell activationGO:0048011 neurotrophin TRK receptor signaling pathwayGO:0048143 astrocyte activationGO:0048167 regulation of synaptic plasticityGO:0048812 neuron projection morphogenesisGO:0050714 positive regulation of protein secretionGO:0050728 negative regulation of inflammatory responseGO:0051881 regulation of mitochondrial membrane potentialGO:0051899 membrane depolarizationGO:0051924 regulation of calcium ion transportGO:0051968 positive regulation of synaptic transmission, glutamatergicGO:0060079 regulation of excitatory postsynaptic membrane potentialGO:0060080 regulation of inhibitory postsynaptic membrane potentialGO:0060134 prepulse inhibitionGO:2001235 positive regulation of apoptotic signaling pathwayGO:0002026 regulation of the force of heart contractionGO:0002028 regulation of sodium ion transportGO:0006754 ATP biosynthetic processGO:0006812 cation transportGO:0006813 potassium ion transportGO:0006814 sodium ion transportGO:0008217 regulation of blood pressureGO:0010107 potassium ion importGO:0015672 monovalent inorganic cation transportGO:0031947 negative regulation of glucocorticoid biosynthetic processGO:0034220 ion transmembrane transportGO:0042493 response to drugGO:0045822 negative regulation of heart contractionGO:0045823 positive regulation of heart contractionGO:0045989 positive regulation of striated muscle contractionGO:0055085 transmembrane transportGO:0060081 membrane hyperpolarizationGO:0071260 cellular response to mechanical stimulusGO:0086004 regulation of cardiac muscle cell contractionGO:0000082 G1/S transition of mitotic cell cycleGO:0000209 protein polyubiquitinationGO:0000902 cell morphogenesisGO:0001101 response to acidGO:0001503 ossificationGO:0001541 ovarian follicle development

GO:0001656 metanephros developmentGO:0001657 ureteric bud developmentGO:0001658 branching involved in ureteric bud morphogenesisGO:0001662 behavioral fear responseGO:0001776 leukocyte homeostasisGO:0001782 B cell homeostasisGO:0001822 kidney developmentGO:0001836 release of cytochrome c from mitochondriaGO:0001836 release of cytochrome c from mitochondriaGO:0001952 regulation of cell-matrix adhesionGO:0002260 lymphocyte homeostasisGO:0002320 lymphoid progenitor cell differentiationGO:0002326 B cell lineage commitmentGO:0002360 T cell lineage commitmentGO:0002520 immune system developmentGO:0003014 renal system processGO:0006470 protein dephosphorylationGO:0006582 melanin metabolic processGO:0006808 regulation of nitrogen utilizationGO:0006874 cellular calcium ion homeostasisGO:0006915 apoptotic processGO:0006959 humoral immune responseGO:0006974 response to DNA damage stimulusGO:0006979 response to oxidative stressGO:0007015 actin filament organizationGO:0007409 axonogenesisGO:0007565 female pregnancyGO:0007569 cell agingGO:0008219 cell deathGO:0008283 cell proliferationGO:0008284 positive regulation of cell proliferationGO:0008285 negative regulation of cell proliferationGO:0008584 male gonad developmentGO:0009314 response to radiationGO:0009605 response to external stimulusGO:0009636 response to toxic substanceGO:0009791 post-embryonic developmentGO:0009887 organ morphogenesisGO:0010039 response to iron ionGO:0010224 response to UV-BGO:0010332 response to gamma radiationGO:0010468 regulation of gene expressionGO:0010507 negative regulation of autophagyGO:0010523 negative regulation of calcium ion transport into cytosolGO:0010559 regulation of glycoprotein biosynthetic processGO:0014031 mesenchymal cell development

GO:0014042 positive regulation of neuron maturationGO:0014911 positive regulation of smooth muscle cell migrationGO:0016049 cell growthGO:0016337 cell-cell adhesionGO:0018105 peptidyl-serine phosphorylationGO:0018107 peptidyl-threonine phosphorylationGO:0021747 cochlear nucleus developmentGO:0022612 gland morphogenesisGO:0022898 regulation of transmembrane transporter activityGO:0030097 hemopoiesisGO:0030183 B cell differentiationGO:0030217 T cell differentiationGO:0030279 negative regulation of ossificationGO:0030307 positive regulation of cell growthGO:0030308 negative regulation of cell growthGO:0030318 melanocyte differentiationGO:0030336 negative regulation of cell migrationGO:0030890 positive regulation of B cell proliferationGO:0031069 hair follicle morphogenesisGO:0031103 axon regenerationGO:0031647 regulation of protein stabilityGO:0032469 endoplasmic reticulum calcium ion homeostasisGO:0032835 glomerulus developmentGO:0032848 negative regulation of cellular pH reductionGO:0032880 regulation of protein localizationGO:0033033 negative regulation of myeloid cell apoptotic processGO:0033077 T cell differentiation in thymusGO:0033138 positive regulation of peptidyl-serine phosphorylationGO:0033689 negative regulation of osteoblast proliferationGO:0034097 response to cytokine stimulusGO:0035094 response to nicotineGO:0035265 organ growthGO:0035872 nucleotide-binding domain, leucine rich repeat containing receptor signaling pathwayGO:0040007 growthGO:0040018 positive regulation of multicellular organism growthGO:0042100 B cell proliferationGO:0042221 response to chemical stimulusGO:0042493 response to drugGO:0042542 response to hydrogen peroxideGO:0042981 regulation of apoptotic processGO:0043029 T cell homeostasisGO:0043066 negative regulation of apoptotic processGO:0043067 regulation of programmed cell deathGO:0043085 positive regulation of catalytic activityGO:0043375 CD8-positive, alpha-beta T cell lineage commitmentGO:0043473 pigmentation

GO:0043496 regulation of protein homodimerization activityGO:0043497 regulation of protein heterodimerization activityGO:0043524 negative regulation of neuron apoptotic processGO:0043583 ear developmentGO:0045069 regulation of viral genome replicationGO:0045087 innate immune responseGO:0045636 positive regulation of melanocyte differentiationGO:0045930 negative regulation of mitotic cell cycleGO:0046671 negative regulation of retinal cell programmed cell deathGO:0046902 regulation of mitochondrial membrane permeabilityGO:0048041 focal adhesion assemblyGO:0048066 developmental pigmentationGO:0048070 regulation of developmental pigmentationGO:0048087 positive regulation of developmental pigmentationGO:0048536 spleen developmentGO:0048538 thymus developmentGO:0048545 response to steroid hormone stimulusGO:0048546 digestive tract morphogenesisGO:0048589 developmental growthGO:0048599 oocyte developmentGO:0048743 positive regulation of skeletal muscle fiber developmentGO:0048753 pigment granule organizationGO:0048873 homeostasis of number of cells within a tissueGO:0050790 regulation of catalytic activityGO:0050853 B cell receptor signaling pathwayGO:0051384 response to glucocorticoid stimulusGO:0051402 neuron apoptotic processGO:0051607 defense response to virusGO:0051726 regulation of cell cycleGO:0051881 regulation of mitochondrial membrane potentialGO:0051902 negative regulation of mitochondrial depolarizationGO:0051924 regulation of calcium ion transportGO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stressGO:0071310 cellular response to organic substanceGO:0072593 reactive oxygen species metabolic processGO:0097193 intrinsic apoptotic signaling pathwayGO:1900740 positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathwayGO:2000811 negative regulation of anoikisGO:2001234 negative regulation of apoptotic signaling pathwayGO:2001244 positive regulation of intrinsic apoptotic signaling pathwayGO:0002866 positive regulation of acute inflammatory respGO:0006950 response to stressGO:0007186 G-protein coupled receptor signaling pathwayGO:0007187 G-protein coupled receptor signaling pathway, coupled to cyclic nucleotideGO:0007188 adenylate cyclase-modulating G-protein coupled receptor signaling pathwayGO:0007283 spermatogenesis

GO:0007568 agingGO:0007584 response to nutrientGO:0007610 behaviorGO:0007611 learning or memoryGO:0007613 memoryGO:0010976 positive regulation of neuron projection developmentGO:0019216 regulation of lipid metabolic processGO:0019233 sensory perception of painGO:0031622 positive regulation of fever generationGO:0031999 negative regulation of fatty acid beta-oxidationGO:0032228 regulation of synaptic transmission, GABAergicGO:0032496 response to lipopolysaccharideGO:0033004 negative regulation of mast cell activationGO:0033602 negative regulation of dopamine secretionGO:0035094 response to nicotineGO:0038171 cannabinoid signaling pathwayGO:0042220 response to cocaineGO:0043065 positive regulation of apoptotic processGO:0043271 negative regulation of ion transportGO:0043278 response to morphineGO:0045471 response to ethanolGO:0045759 negative regulation of action potentialGO:0045776 negative regulation of blood pressureGO:0045777 positive regulation of blood pressureGO:0050796 regulation of insulin secretionGO:0051001 negative regulation of nitric-oxide synthase activityGO:0051966 regulation of synaptic transmission, glutamatergicGO:0060135 maternal process involved in female pregnancyGO:0060259 regulation of feeding behaviorGO:0060405 regulation of penile erectionGO:0001659 temperature homeostasisGO:0001661 conditioned taste aversionGO:0001662 behavioral fear responseGO:0001963 synaptic transmission, dopaminergicGO:0001975 response to amphetamineGO:0006606 protein import into nucleusGO:0006936 muscle contractionGO:0007186 G-protein coupled receptor signaling pathwayGO:0007187 G-protein coupled receptor signaling pathway, coupled to cyclic nucleotideGO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathwayGO:0007190 activation of adenylate cyclase activityGO:0007191 adenylate cyclase-activating dopamine receptor signaling pathwayGO:0007212 dopamine receptor signaling pathwayGO:0007416 synapse assemblyGO:0007610 behaviorGO:0007612 learning

GO:0007613 memoryGO:0007617 mating behaviorGO:0007625 grooming behaviorGO:0007626 locomotory behaviorGO:0007628 adult walking behaviorGO:0007631 feeding behaviorGO:0008306 associative learningGO:0008542 visual learningGO:0010579 positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathwayGO:0014002 astrocyte developmentGO:0015872 dopamine transportGO:0019226 transmission of nerve impulseGO:0019228 regulation of action potential in neuronGO:0021542 dentate gyrus developmentGO:0021756 striatum developmentGO:0021766 hippocampus developmentGO:0021853 cerebral cortex GABAergic interneuron migrationGO:0030335 positive regulation of cell migrationGO:0030432 peristalsisGO:0030819 positive regulation of cAMP biosynthetic processGO:0035106 operant conditioningGO:0042053 regulation of dopamine metabolic processGO:0042220 response to cocaineGO:0042311 vasodilationGO:0042417 dopamine metabolic processGO:0042493 response to drugGO:0043268 positive regulation of potassium ion transportGO:0046323 glucose importGO:0046960 sensitizationGO:0048148 behavioral response to cocaineGO:0051281 positive regulation of release of sequestered calcium ion into cytosolGO:0051482 elevation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathwayGO:0051584 regulation of dopamine uptake involved in synaptic transmissionGO:0051968 positive regulation of synaptic transmission, glutamatergicGO:0060134 prepulse inhibitionGO:0060158 phospholipase C-activating dopamine receptor signaling pathwayGO:0060291 long-term synaptic potentiationGO:0060292 long term synaptic depressionGO:0071870 cellular response to catecholamine stimulusGO:0001661 conditioned taste aversionGO:0001964 startle responseGO:0001967 suckling behaviorGO:0001975 response to amphetamineGO:0006810 transportGO:0006812 cation transportGO:0006816 calcium ion transport

GO:0006874 cellular calcium ion homeostasisGO:0007268 synaptic transmissionGO:0007585 respiratory gaseous exchangeGO:0007611 learning or memoryGO:0007612 learningGO:0007613 memoryGO:0007616 long-term memoryGO:0008306 associative learningGO:0008344 adult locomotory behaviorGO:0008355 olfactory learningGO:0008542 visual learningGO:0010646 regulation of cell communicationGO:0010942 positive regulation of cell deathGO:0014070 response to organic cyclic compoundGO:0014075 response to amine stimulusGO:0018964 propylene metabolic processGO:0019233 sensory perception of painGO:0021586 pons maturationGO:0021987 cerebral cortex developmentGO:0035176 social behaviorGO:0035235 ionotropic glutamate receptor signaling pathwayGO:0035249 synaptic transmission, glutamatergicGO:0042391 regulation of membrane potentialGO:0043065 positive regulation of apoptotic processGO:0043278 response to morphineGO:0043523 regulation of neuron apoptotic processGO:0043524 negative regulation of neuron apoptotic processGO:0043576 regulation of respiratory gaseous exchangeGO:0045471 response to ethanolGO:0045944 positive regulation of transcription from RNA polymerase II promoterGO:0048167 regulation of synaptic plasticityGO:0048168 regulation of neuronal synaptic plasticityGO:0048169 regulation of long-term neuronal synaptic plasticityGO:0048511 rhythmic processGO:0048814 regulation of dendrite morphogenesisGO:0050770 regulation of axonogenesisGO:0050905 neuromuscular processGO:0051592 response to calcium ionGO:0051963 regulation of synapse assemblyGO:0055074 calcium ion homeostasisGO:0060079 regulation of excitatory postsynaptic membrane potentialGO:0060134 prepulse inhibitionGO:0060179 male mating behaviorGO:0060992 response to fungicideGO:0070588 calcium ion transmembrane transportGO:0071287 cellular response to manganese ion

GO:2000463 positive regulation of excitatory postsynaptic membrane potentialGO:0001964 startle responseGO:0001975 response to amphetamineGO:0006810 transportGO:0006816 calcium ion transportGO:0007215 glutamate receptor signaling pathwayGO:0007268 synaptic transmissionGO:0007611 learning or memoryGO:0007612 learningGO:0007613 memoryGO:0008104 protein localizationGO:0008542 visual learningGO:0009611 response to woundingGO:0019233 sensory perception of painGO:0022008 neurogenesisGO:0030431 sleepGO:0033058 directional locomotionGO:0040011 locomotionGO:0042177 negative regulation of protein catabolic processGO:0042391 regulation of membrane potentialGO:0042417 dopamine metabolic processGO:0042428 serotonin metabolic processGO:0042493 response to drugGO:0043065 positive regulation of apoptotic processGO:0045471 response to ethanolGO:0048167 regulation of synaptic plasticityGO:0050804 regulation of synaptic transmissionGO:0051930 regulation of sensory perception of painGO:0060078 regulation of postsynaptic membrane potentialGO:0060079 regulation of excitatory postsynaptic membrane potentialGO:0070588 calcium ion transmembrane transportGO:0000122 negative regulation of transcription from RNAGO:0000278 mitotic cell cycleGO:0006338 chromatin remodelingGO:0006351 transcription, DNA-dependentGO:0006367 transcription initiation from RNA polymerase II promoterGO:0006476 protein deacetylationGO:0007179 transforming growth factor beta receptor signaling pathwayGO:0007219 Notch signaling pathwayGO:0007596 blood coagulationGO:0008284 positive regulation of cell proliferationGO:0009913 epidermal cell differentiationGO:0010467 gene expressionGO:0010870 positive regulation of receptor biosynthetic processGO:0016568 chromatin modificationGO:0016575 histone deacetylation

GO:0019048 virus-host interactionGO:0042475 odontogenesis of dentin-containing toothGO:0042733 embryonic digit morphogenesisGO:0043066 negative regulation of apoptotic processGO:0043922 negative regulation by host of viral transcriptionGO:0045786 negative regulation of cell cycleGO:0045892 negative regulation of transcription, DNA-dependentGO:0045893 positive regulation of transcription, DNA-dependentGO:0045944 positive regulation of transcription from RNA polymerase II promoterGO:0048011 neurotrophin TRK receptor signaling pathwayGO:0060766 negative regulation of androgen receptor signaling pathwayGO:0060789 hair follicle placode formationGO:0061029 eyelid development in camera-type eyeGO:0061198 fungiform papilla formationGO:0070932 histone H3 deacetylationGO:0070933 histone H4 deacetylationGO:0000122 negative regulation of transcription from RNAGO:0006338 chromatin remodelingGO:0006344 maintenance of chromatin silencingGO:0006351 transcription, DNA-dependentGO:0006476 protein deacetylationGO:0007596 blood coagulationGO:0008284 positive regulation of cell proliferationGO:0009913 epidermal cell differentiationGO:0010870 positive regulation of receptor biosynthetic processGO:0010977 negative regulation of neuron projection developmentGO:0016358 dendrite developmentGO:0016575 histone deacetylationGO:0021766 hippocampus developmentGO:0030182 neuron differentiationGO:0032967 positive regulation of collagen biosynthetic processGO:0042475 odontogenesis of dentin-containing toothGO:0042733 embryonic digit morphogenesisGO:0043066 negative regulation of apoptotic processGO:0043433 negative regulation of sequence-specific DNA binding transcription factor activityGO:0045347 negative regulation of MHC class II biosynthetic processGO:0045786 negative regulation of cell cycleGO:0045862 positive regulation of proteolysisGO:0045892 negative regulation of transcription, DNA-dependentGO:0045893 positive regulation of transcription, DNA-dependentGO:0045944 positive regulation of transcription from RNA polymerase II promoterGO:0048011 neurotrophin TRK receptor signaling pathwayGO:0048714 positive regulation of oligodendrocyte differentiationGO:0051091 positive regulation of sequence-specific DNA binding transcription factor activityGO:0051896 regulation of protein kinase B signaling cascadeGO:0055013 cardiac muscle cell development

GO:0060044 negative regulation of cardiac muscle cell proliferationGO:0060297 regulation of sarcomere organizationGO:0060789 hair follicle placode formationGO:0061029 eyelid development in camera-type eyeGO:0061198 fungiform papilla formationGO:0090090 negative regulation of canonical Wnt receptor signaling pathwayGO:0090311 regulation of protein deacetylationGO:0006351 transcription, DNA-dependentGO:0000122 negative regulation of transcription from RNA polymerase II promoterGO:0043066 negative regulation of apoptotic processGO:0044255 cellular lipid metabolic processGO:0044281 small molecule metabolic processGO:0045892 negative regulation of transcription, DNA-dependentGO:0051225 spindle assemblyGO:0007346 regulation of mitotic cell cycleGO:0007219 Notch signaling pathwayGO:0016568 chromatin modificationGO:0040014 regulation of multicellular organism growthGO:0032922 circadian regulation of gene expressionGO:0016575 histone deacetylationGO:0046329 negative regulation of JNK cascadeGO:0045786 negative regulation of cell cycleGO:0006476 protein deacetylationGO:0048011 neurotrophin TRK receptor signaling pathwayGO:0000165 MAPK cascadeGO:0000186 activation of MAPKK activityGO:0000187 activation of MAPK activityGO:0000189 MAPK import into nucleusGO:0002224 toll-like receptor signaling pathwayGO:0002755 MyD88-dependent toll-like receptor signaling pathwayGO:0002756 MyD88-independent toll-like receptor signaling pathwayGO:0006351 transcription, DNA-dependentGO:0006468 protein phosphorylationGO:0006915 apoptotic processGO:0006917 induction of apoptosisGO:0006935 chemotaxisGO:0006950 response to stressGO:0006974 response to DNA damage stimulusGO:0007049 cell cycleGO:0007165 signal transductionGO:0007173 epidermal growth factor receptor signaling pathwayGO:0007264 small GTPase mediated signal transductionGO:0007265 Ras protein signal transductionGO:0007268 synaptic transmissionGO:0007411 axon guidanceGO:0007596 blood coagulation

GO:0008284 positive regulation of cell proliferationGO:0008286 insulin receptor signaling pathwayGO:0008543 fibroblast growth factor receptor signaling pathwayGO:0009636 response to toxic substanceGO:0009887 organ morphogenesisGO:0010800 positive regulation of peptidyl-threonine phosphorylationGO:0018105 peptidyl-serine phosphorylationGO:0019048 virus-host interactionGO:0019233 sensory perception of painGO:0019858 cytosine metabolic processGO:0030168 platelet activationGO:0030335 positive regulation of cell migrationGO:0031663 lipopolysaccharide-mediated signaling pathwayGO:0032496 response to lipopolysaccharideGO:0032872 regulation of stress-activated MAPK cascadeGO:0033598 mammary gland epithelial cell proliferationGO:0034134 toll-like receptor 2 signaling pathwayGO:0034138 toll-like receptor 3 signaling pathwayGO:0034142 toll-like receptor 4 signaling pathwayGO:0034146 toll-like receptor 5 signaling pathwayGO:0034162 toll-like receptor 9 signaling pathwayGO:0034166 toll-like receptor 10 signaling pathwayGO:0035556 intracellular signal transductionGO:0035666 TRIF-dependent toll-like receptor signaling pathwayGO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosisGO:0038123 toll-like receptor TLR1:TLR2 signaling pathwayGO:0038124 toll-like receptor TLR6:TLR2 signaling pathwayGO:0038127 ERBB signaling pathwayGO:0042221 response to chemical stimulusGO:0043330 response to exogenous dsRNAGO:0043627 response to estrogen stimulusGO:0045087 innate immune responseGO:0045596 negative regulation of cell differentiationGO:0045727 positive regulation of translationGO:0045893 positive regulation of transcription, DNA-dependentGO:0048011 neurotrophin TRK receptor signaling pathwayGO:0050852 T cell receptor signaling pathwayGO:0050853 B cell receptor signaling pathwayGO:0051090 regulation of sequence-specific DNA binding transcription factor activityGO:0051403 stress-activated MAPK cascadeGO:0051493 regulation of cytoskeleton organizationGO:0060397 JAK-STAT cascade involved in growth hormone signaling pathwayGO:0060716 labyrinthine layer blood vessel developmentGO:0070371 ERK1 and ERK2 cascadeGO:0070849 response to epidermal growth factor stimulusGO:0072584 caveolin-mediated endocytosis

GO:0090170 regulation of Golgi inheritanceGO:2000641 regulation of early endosome to late endosome transport

GO:0000122 negative regulation of transcription from RNA polymerase II promoterGO:0001818 negative regulation of cytokine productionGO:0002224 toll-like receptor signaling pathwayGO:0002755 MyD88-dependent toll-like receptor signaling pathwayGO:0002756 MyD88-independent toll-like receptor signaling pathwayGO:0006355 regulation of transcription, DNA-dependentGO:0006366 transcription from RNA polymerase II promoterGO:0006915 apoptotic processGO:0006954 inflammatory responseGO:0006979 response to oxidative stressGO:0007165 signal transductionGO:0009617 response to bacteriumGO:0010744 positive regulation of macrophage derived foam cell differentiationGO:0010884 positive regulation of lipid storageGO:0010956 negative regulation of calcidiol 1-monooxygenase activityGO:0010957 negative regulation of vitamin D biosynthetic processGO:0031293 membrane protein intracellular domain proteolysisGO:0032269 negative regulation of cellular protein metabolic processGO:0032375 negative regulation of cholesterol transportGO:0032481 positive regulation of type I interferon productionGO:0034134 toll-like receptor 2 signaling pathwayGO:0034138 toll-like receptor 3 signaling pathwayGO:0034142 toll-like receptor 4 signaling pathwayGO:0034146 toll-like receptor 5 signaling pathwayGO:0034162 toll-like receptor 9 signaling pathwayGO:0034166 toll-like receptor 10 signaling pathwayGO:0035666 TRIF-dependent toll-like receptor signaling pathwayGO:0038123 toll-like receptor TLR1:TLR2 signaling pathwayGO:0038124 toll-like receptor TLR6:TLR2 signaling pathwayGO:0043066 negative regulation of apoptotic processGO:0045083 negative regulation of interleukin-12 biosynthetic processGO:0045087 innate immune responseGO:0045892 negative regulation of transcription, DNA-dependentGO:0045893 positive regulation of transcription, DNA-dependentGO:0045944 positive regulation of transcription from RNA polymerase II promoterGO:0046688 response to copper ionGO:0048011 neurotrophin TRK receptor signaling pathwayGO:0050728 negative regulation of inflammatory responseGO:0050852 T cell receptor signaling pathwayGO:0051092 positive regulation of NF-kappaB transcription factor activityGO:0071260 cellular response to mechanical stimulusGO:0071347 cellular response to interleukin-1GO:0090263 positive regulation of canonical Wnt receptor signaling pathway

GO:1900127 positive regulation of hyaluronan biosynthetic process

GO:0000002 mitochondrial genome maintenanceGO:0006091 generation of precursor metabolites and energyGO:0006112 energy reserve metabolic processGO:0006810 transportGO:0008637 apoptotic mitochondrial changesGO:0015853 adenine transportGO:0016032 viral reproductionGO:0019048 virus-host interactionGO:0044281 small molecule metabolic processGO:0050796 regulation of insulin secretionGO:0060547 negative regulation of necrotic cell deathGO:0001504 neurotransmitter uptakeGO:0006112 energy reserve metabolic processGO:0007268 synaptic transmissionGO:0007269 neurotransmitter secretionGO:0014047 glutamate secretionGO:0016081 synaptic vesicle docking involved in exocytosisGO:0016192 vesicle-mediated transportGO:0044281 small molecule metabolic processGO:0050796 regulation of insulin secretionGO:0000086 G2/M transition of mitotic cell cycleGO:0000278 mitotic cell cycleGO:0006184 GTP catabolic processGO:0006928 cellular component movementGO:0007017 microtubule-based processGO:0009987 cellular processGO:0030705 cytoskeleton-dependent intracellular transportGO:0042267 natural killer cell mediated cytotoxicityGO:0051225 spindle assemblyGO:0000187 activation of MAPK activityGO:0001666 response to hypoxiaGO:0006006 glucose metabolic processGO:0006351 transcription, DNA-dependentGO:0006355 regulation of transcription, DNA-dependentGO:0006468 protein phosphorylationGO:0006633 fatty acid biosynthetic processGO:0006695 cholesterol biosynthetic process

GO:0006914 autophagyGO:0006950 response to stressGO:0007050 cell cycle arrestGO:0007165 signal transductionGO:0008284 positive regulation of cell proliferationGO:0008286 insulin receptor signaling pathwayGO:0008610 lipid biosynthetic processGO:0009631 cold acclimationGO:0010508 positive regulation of autophagyGO:0010628 positive regulation of gene expressionGO:0014823 response to activityGO:0016055 Wnt receptor signaling pathwayGO:0019395 fatty acid oxidationGO:0031000 response to caffeineGO:0031669 cellular response to nutrient levelsGO:0032007 negative regulation of TOR signaling cascadeGO:0035404 histone-serine phosphorylationGO:0042149 cellular response to glucose starvationGO:0042593 glucose homeostasisGO:0042752 regulation of circadian rhythmGO:0043066 negative regulation of apoptotic processGO:0045542 positive regulation of cholesterol biosynthetic processGO:0045821 positive regulation of glycolysisGO:0046318 negative regulation of glucosylceramide biosynthetic processGO:0048511 rhythmic processGO:0050995 negative regulation of lipid catabolic processGO:0051291 protein heterooligomerizationGO:0055089 fatty acid homeostasisGO:0060627 regulation of vesicle-mediated transportGO:0070301 cellular response to hydrogen peroxideGO:0071361 cellular response to ethanolGO:0071417 cellular response to organic nitrogenGO:0071456 cellular response to hypoxiaGO:2000505 regulation of energy homeostasisGO:2001274 negative regulation of glucose import in response to insulin stimulus

No of KEGG pathway KEGG Id KEGG pathway30 hsa04726 Serotonergic synapse - Homo sapiens (human)

hsa04270 Vascular smooth muscle contraction - Homo sapiens (human)hsa04020 Calcium signaling pathway - Homo sapiens (human)hsa04022 cGMP-PKG signaling pathway - Homo sapiens (human)hsa04070 Phosphatidylinositol signaling system - Homo sapiens (human)hsa04114 Oocyte meiosis - Homo sapiens (human)

epidermal growth factor receptor signaling pathway hsa04210 Apoptosis - Homo sapiens (human)hsa04540 Gap junction - Homo sapiens (human)hsa04611 Platelet activation - Homo sapiens (human)

fibroblast growth factor receptor signaling pathway hsa04713 Circadian entrainment - Homo sapiens (human)hsa04720 Long-term potentiation - Homo sapiens (human)hsa04723 Retrograde endocannabinoid signaling - Homo sapiens (human)

endoplasmic reticulum calcium ion homeostasis hsa04724 Glutamatergic synapse - Homo sapiens (human)Fc-gamma receptor signaling pathway involved in phagocytosis hsa04725 Cholinergic synapse - Homo sapiens (human)

hsa04728 Dopaminergic synapse - Homo sapiens (human)hsa04730 Long-term depression - Homo sapiens (human)hsa04750 Inflammatory mediator regulation of TRP channels - Homo sapiens (human)hsa04912 GnRH signaling pathway - Homo sapiens (human)hsa04915 Estrogen signaling pathway - Homo sapiens (human)hsa04918 Thyroid hormone synthesis - Homo sapiens (human)

release of sequestered calcium ion into cytosol hsa04921 Oxytocin signaling pathway - Homo sapiens (human)hsa04922 Glucagon signaling pathway - Homo sapiens (human)

intrinsic apoptotic signaling pathway in response to endoplasmic reticulum shsa04924 Renin secretion - Homo sapiens (human)hsa04925 Aldosterone synthesis and secretion - Homo sapiens (human)hsa04970 Salivary secretion - Homo sapiens (human)hsa04971 Gastric acid secretion - Homo sapiens (human)hsa04972 Pancreatic secretion - Homo sapiens (human)hsa05010 Alzheimer's disease - Homo sapiens (human)hsa05016 Huntington's disease - Homo sapiens (human)hsa05205 Proteoglycans in cancer - Homo sapiens (human)

9 hsa04110 Cell cycle - Homo sapiens (human)hsa05206 MicroRNAs in cancer - Homo sapiens (human)hsa04064 NF-kappa B signaling pathway - Homo sapiens (human)

double-strand break repair via homologous recombination hsa04068 FoxO signaling pathway - Homo sapiens (human)hsa04115 p53 signaling pathway - Homo sapiens (human)hsa04210 Apoptosis - Homo sapiens (human)hsa05166 HTLV-I infection - Homo sapiens (human)hsa05202 Transcriptional misregulation in cancer - Homo sapiens (human)hsa02010 ABC transporters - Homo sapiens (human)

DNA damage induced protein phosphorylationDNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

intrinsic apoptotic signaling pathway in response to DNA damage

phosphatidylinositol-3-phosphate biosynthetic process

positive regulation of DNA damage response, signal transduction by p53 class mediatorpositive regulation of neuron apoptotic process

32 hsa04713 Circadian entrainment - Homo sapiens (human)hsa04744 Phototransduction - Homo sapiens (human)hsa05031 Amphetamine addiction - Homo sapiens (human)hsa05214 Glioma - Homo sapiens (human)hsa04014 Ras signaling pathway - Homo sapiens (human)hsa04015 Rap1 signaling pathway - Homo sapiens (human)hsa04020 Calcium signaling pathway - Homo sapiens (human)hsa04022 cGMP-PKG signaling pathway - Homo sapiens (human)hsa04024 cAMP signaling pathway - Homo sapiens (human)

epidermal growth factor receptor signaling pathway hsa04070 Phosphatidylinositol signaling system - Homo sapiens (human)hsa04114 Oocyte meiosis - Homo sapiens (human)hsa04261 Adrenergic signaling in cardiomyocytes - Homo sapiens (human)hsa04270 Vascular smooth muscle contraction - Homo sapiens (human)hsa04720 Long-term potentiation - Homo sapiens (human)

fibroblast growth factor receptor signaling pathway hsa04722 Neurotrophin signaling pathway - Homo sapiens (human)regulation of release of sequestered calcium ion into cytosol by sarcoplasmi hsa04728 Dopaminergic synapse - Homo sapiens (human)regulation of cardiac muscle contraction by regulation of the release of sequhsa04740 Olfactory transduction - Homo sapiens (human)

hsa04750 Inflammatory mediator regulation of TRP channels - Homo sapiens (human)

hsa04910 Insulin signaling pathway - Homo sapiens (human)positive regulation of cyclic nucleotide metabolic process hsa04912 GnRH signaling pathway - Homo sapiens (human)

hsa04915 Estrogen signaling pathway - Homo sapiens (human)positive regulation of phosphoprotein phosphatase activity hsa04916 Melanogenesis - Homo sapiens (human)positive regulation of protein dephosphorylation hsa04921 Oxytocin signaling pathway - Homo sapiens (human)

hsa04922 Glucagon signaling pathway - Homo sapiens (human)hsa04924 Renin secretion - Homo sapiens (human)hsa04925 Aldosterone synthesis and secretion - Homo sapiens (human)hsa04970 Salivary secretion - Homo sapiens (human)hsa04971 Gastric acid secretion - Homo sapiens (human)hsa05010 Alzheimer's disease - Homo sapiens (human)

positive regulation of cyclic-nucleotide phosphodiesterase activity hsa05034 Alcoholism - Homo sapiens (human)hsa05133 Pertussis - Homo sapiens (human)hsa05152 Tuberculosis - Homo sapiens (human)

negative regulation of ryanodine-sensitive calcium-release channel activitypositive regulation of ryanodine-sensitive calcium-release channel activityregulation of cell communication by electrical coupling involved in cardiac conduction

7 hsa04144 Endocytosis - Homo sapiens (human)hsa04510 Focal adhesion - Homo sapiens (human)hsa05100 Bacterial invasion of epithelial cells - Homo sapiens (human)hsa05205 Proteoglycans in cancer - Homo sapiens (human)hsa05416 Viral myocarditis - Homo sapiens (human)hsa04020 Calcium signaling pathway - Homo sapiens (human)

negative regulation of endothelial cell proliferation hsa04728 Dopaminergic synapse - Homo sapiens (human)negative regulation of cytokine-mediated signaling pathway

regulation of the force of heart contraction by chemical signal

positive regulation of calcium ion transport into cytosol

negative regulation of epithelial cell differentiation

negative regulation of peptidyl-serine phosphorylationpositive regulation of peptidyl-serine phosphorylation

negative regulation of tyrosine phosphorylation of Stat5 protein

negative regulation of nitric oxide biosynthetic process

negative regulation of nitric-oxide synthase activity

negative regulation of canonical Wnt receptor signaling pathwaypositive regulation of canonical Wnt receptor signaling pathway

receptor internalization involved in canonical Wnt receptor signaling pathway

positive regulation of extrinsic apoptotic signaling pathwaypositive regulation of intrinsic apoptotic signaling pathway

9 hsa01200 Carbon metabolism - Homo sapiens (human)hsa00280 Valine, leucine and isoleucine degradation - Homo sapiens (human)

mitochondrial electron transport, NADH to ubiquinone hsa01100 Metabolic pathways - Homo sapiens (human)hsa00020 Citrate cycle (TCA cycle) - Homo sapiens (human)hsa00010 Glycolysis / Gluconeogenesis - Homo sapiens (human)hsa00260 Glycine, serine and threonine metabolism - Homo sapiens (human)hsa00620 Pyruvate metabolism - Homo sapiens (human)hsa00630 Glyoxylate and dicarboxylate metabolism - Homo sapiens (human)

regulation of acetyl-CoA biosynthetic process from pyruvate hsa00640 Propanoate metabolism - Homo sapiens (human)cellular nitrogen compound metabolic process

37 hsa05220 Chronic myeloid leukemia hsa05218 Melanoma

negative regulation of transcription from RNA polymerase II promoter hsa05217 Basal cell carcinoma hsa05219 Bladder cancer hsa05203 Viral carcinogenesis hsa05206 MicroRNAs in cancer hsa05230 Central carbon metabolism in cancer

T cell proliferation involved in immune response hsa04115 p53 signaling pathway hsa04210 Apoptosis hsa05166 HTLV-I infection hsa04211 Longevity regulating pathway hsa04919 Thyroid hormone signaling pathway hsa05161 Hepatitis B hsa05200 Pathways in cancer hsa05202 Transcriptional misregulation in cancer hsa05213 Endometrial cancer hsa05214 Glioma hsa04010 MAPK signaling pathway hsa04071 Sphingolipid signaling pathway hsa04110 Cell cycle

DNA damage response, signal transduction by p53 class mediator resulting in hsa04151 PI3K-Akt signaling pathway DNA damage response, signal transduction by p53 class mediator resulting inhsa04310 Wnt signaling pathway

hsa04390 Hippo signaling pathway hsa04722 Neurotrophin signaling pathway hsa05014 Amyotrophic lateral sclerosis (ALS) hsa05016 Huntington's disease

transforming growth factor beta receptor signaling pathway hsa05160 Hepatitis C hsa05162 Measles hsa05168 Herpes simplex infection hsa05169 Epstein-Barr virus infection

negative regulation of neuroblast proliferation hsa05205 Proteoglycans in cancer

hsa05210 Colorectal cancer hsa05212 Pancreatic cancer hsa05215 Prostate cancer hsa05216 Thyroid cancer hsa05222 Small cell lung cancer hsa05223 Non-small cell lung cancer

embryo development ending in birth or egg hatching

positive regulation of cardiac muscle cell apoptotic process

DNA damage response, signal transduction by p53 class mediatornegative regulation of transforming growth factor beta receptor signaling pathway

intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of neuron apoptotic processnegative regulation of transcription, DNA-dependentpositive regulation of transcription, DNA-dependentpositive regulation of transcription from RNA polymerase II promoter

regulation of mitochondrial membrane permeability

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of thymocyte apoptotic process

intrinsic apoptotic signaling pathway by p53 class mediatorpositive regulation of release of cytochrome c from mitochondria

oxidative stress-induced premature senescence

negative regulation of reactive oxygen species metabolic processpositive regulation of reactive oxygen species metabolic processpositive regulation of intrinsic apoptotic signaling pathway

1 hsa03040 Spliceosome - Homo sapiens (human)

4 hsa04130 SNARE interactions in vesicular transport hsa04721 Synaptic vesicle cycle hsa05031 Amphetamine addiction hsa04911 Insulin secretion

synaptic vesicle docking involved in exocytosis

12 hsa00563 Glycosylphosphatidylinositol(GPI)-anchor biosynthesis hsa05120 Epithelial cell signaling in Helicobacter pylori infection hsa01100 Metabolic pathways hsa00010 Glycolysis / Gluconeogenesis hsa01200 Carbon metabolism hsa00030 Pentose phosphate pathway hsa00510 N-Glycan biosynthesis hsa00564 Glycerophospholipid metabolism

hsa00500 Starch and sucrose metabolism negative regulation of cysteine-type endopeptidase activity involved in apophsa00520 Amino sugar and nucleotide sugar metabolism negative regulation of neuron apoptotic process hsa05144 Malaria

hsa05145 Toxoplasmosis

6 hsa00190 Oxidative phosphorylation hsa01100 Metabolic pathways hsa04932 Non-alcoholic fatty liver disease (NAFLD) hsa05010 Alzheimer's disease hsa05012 Parkinson's disease hsa05016 Huntington's disease

25 hsa05203 Viral carcinogenesis hsa05161 Hepatitis B hsa05206 MicroRNAs in cancer

transcription initiation from RNA polymerase II promoter hsa05211 Renal cell carcinoma hsa04024 cAMP signaling pathway hsa04066 HIF-1 signaling pathway hsa04068 FoxO signaling pathway hsa04110 Cell cycle hsa04310 Wnt signaling pathway hsa04330 Notch signaling pathway hsa04350 TGF-beta signaling pathway hsa04520 Adherens junction hsa04630 Jak-STAT signaling pathway hsa04720 Long-term potentiation hsa04916 Melanogenesis hsa04919 Thyroid hormone signaling pathway hsa04922 Glucagon signaling pathway hsa05016 Huntington's disease hsa05152 Tuberculosis

positive regulation of transcription, DNA-dependent hsa05164 Influenza A positive regulation of transcription from RNA polymerase II promoter hsa05166 HTLV-I infection regulation of transcription from RNA polymerase II promoter in response to hsa05168 Herpes simplex infection

hsa05169 Epstein-Barr virus infection hsa05200 Pathways in cancer hsa05215 Prostate cancer

4 hsa04071 Sphingolipid signaling pathway hsa04142 Lysosome hsa04210 Apoptosis

antigen processing and presentation of exogenous peptide antigen via MHC clhsa05152 Tuberculosis

1 hsa04668 TNF signaling pathway dynamin polymerization involved in mitochondrial fission

cellular component disassembly involved in execution phase of apoptosis

mitochondrial fragmentation involved in apoptotic process

membrane fission involved in mitochondrial fissionpositive regulation of release of cytochrome c from mitochondria

positive regulation of intrinsic apoptotic signaling pathway6 hsa04072 Phospholipase D signaling pathway

hsa04721 Synaptic vesicle cycle hsa04961 Endocrine and other factor-regulated calcium reabsorption hsa04144 Endocytosis hsa04666 Fc gamma R-mediated phagocytosis hsa05100 Bacterial invasion of epithelial cells

antigen processing and presentation of exogenous peptide antigen via MHC class II

positive regulation of transcription, DNA-dependent

70 hsa04213 Longevity regulating pathway - multiple species hsa05205 Proteoglycans in cancer hsa04071 Sphingolipid signaling pathway

positive regulation of protein phosphorylation hsa04150 mTOR signaling pathway hsa04152 AMPK signaling pathway hsa04211 Longevity regulating pathway hsa04550 Signaling pathways regulating pluripotency of stem cells hsa04915 Estrogen signaling pathway hsa04917 Prolactin signaling pathway hsa05212 Pancreatic cancer hsa05214 Glioma hsa05223 Non-small cell lung cancer hsa04010 MAPK signaling pathway hsa04012 ErbB signaling pathway hsa04014 Ras signaling pathway hsa04015 Rap1 signaling pathway

hsa04022 cGMP-PKG signaling pathway hsa04024 cAMP signaling pathway

epidermal growth factor receptor signaling pathway hsa04062 Chemokine signaling pathway hsa04066 HIF-1 signaling pathway hsa04068 FoxO signaling pathway hsa04072 Phospholipase D signaling pathway hsa04151 PI3K-Akt signaling pathway hsa04210 Apoptosis hsa04261 Adrenergic signaling in cardiomyocytes

fibroblast growth factor receptor signaling pathway hsa04370 VEGF signaling pathway hsa04380 Osteoclast differentiation hsa04510 Focal adhesion hsa04530 Tight junction hsa04611 Platelet activation hsa04620 Toll-like receptor signaling pathway

negative regulation of plasma membrane long-chain fatty acid transport hsa04630 Jak-STAT signaling pathway hsa04660 T cell receptor signaling pathway

positive regulation of glucose metabolic process hsa04662 B cell receptor signaling pathway hsa04664 Fc epsilon RI signaling pathway hsa04666 Fc gamma R-mediated phagocytosis hsa04668 TNF signaling pathway hsa04722 Neurotrophin signaling pathway hsa04725 Cholinergic synapse hsa04728 Dopaminergic synapse hsa04910 Insulin signaling pathway hsa04914 Progesterone-mediated oocyte maturation hsa04919 Thyroid hormone signaling pathway hsa04920 Adipocytokine signaling pathway hsa04922 Glucagon signaling pathway hsa04923 Regulation of lipolysis in adipocytes hsa04931 Insulin resistance hsa04932 Non-alcoholic fatty liver disease (NAFLD) hsa04933 AGE-RAGE signaling pathway in diabetic complications hsa04973 Carbohydrate digestion and absorption hsa05142 Chagas disease (American trypanosomiasis)

positive regulation of cyclin-dependent protein serine/threonine kinase activhsa05145 Toxoplasmosis negative regulation of fatty acid beta-oxidation hsa05152 Tuberculosis

hsa05160 Hepatitis C positive regulation of cellular protein metabolic process hsa05161 Hepatitis B peripheral nervous system myelin maintenance hsa05162 Measles positive regulation of proteasomal ubiquitin-dependent protein catabolic pr hsa05164 Influenza A

hsa05166 HTLV-I infection hsa05169 Epstein-Barr virus infection

positive regulation of peptidyl-serine phosphorylation hsa05200 Pathways in cancer hsa05210 Colorectal cancer hsa05211 Renal cell carcinoma

hsa05213 Endometrial cancer hsa05215 Prostate cancer hsa05218 Melanoma hsa05220 Chronic myeloid leukemia

negative regulation of cysteine-type endopeptidase activity involved in apophsa05221 Acute myeloid leukemia hsa05222 Small cell lung cancer

positive regulation of blood vessel endothelial cell migration hsa05230 Central carbon metabolism in cancer hsa05231 Choline metabolism in cancer

positive regulation of nitric oxide biosynthetic process

positive regulation of glycogen biosynthetic process

positive regulation of transcription from RNA polymerase II promoter

positive regulation of lipid biosynthetic processinsulin-like growth factor receptor signaling pathway

positive regulation of nitric-oxide synthase activitypositive regulation of sequence-specific DNA binding transcription factor activity

glycogen cell differentiation involved in embryonic placenta development

cellular response to epidermal growth factor stimulus

positive regulation of establishment of protein localization to plasma membranenegative regulation of release of cytochrome c from mitochondria

positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway

19 hsa04215 Apoptosis - multiple species hsa05142 Chagas disease (American trypanosomiasis) hsa04115 p53 signaling pathway

MyD88-independent toll-like receptor signaling pathway hsa04210 Apoptosis hsa04620 Toll-like receptor signaling pathway hsa04621 NOD-like receptor signaling pathway

activation of cysteine-type endopeptidase activity involved in apoptotic prochsa04622 RIG-I-like receptor signaling pathway cellular component disassembly involved in execution phase of apoptosis hsa04668 TNF signaling pathway

hsa04932 Non-alcoholic fatty liver disease (NAFLD) hsa05010 Alzheimer's disease hsa05016 Huntington's disease hsa05134 Legionellosis hsa05145 Toxoplasmosis hsa05152 Tuberculosis hsa05161 Hepatitis B hsa05168 Herpes simplex infection hsa05200 Pathways in cancer hsa05416 Viral myocarditis

TRIF-dependent toll-like receptor signaling pathway hsa05203 Viral carcinogenesis nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway

positive regulation of I-kappaB kinase/NF-kappaB cascadenegative regulation of I-kappaB kinase/NF-kappaB cascade

positive regulation of macrophage differentiation

proteolysis involved in cellular protein catabolic processnucleotide-binding oligomerization domain containing signaling pathway

activation of cysteine-type endopeptidase activitypositive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway

4 hsa00260 Glycine, serine and threonine metabolism hsa01100 Metabolic pathways hsa00270 Cysteine and methionine metabolism hsa01230 Biosynthesis of amino acids

cysteine biosynthetic process via cystathionine

cellular nitrogen compound metabolic process

maternal process involved in female pregnancycartilage development involved in endochondral bone morphogenesis

6 hsa04015 Rap1 signaling pathway hsa04020 Calcium signaling pathway hsa04024 cAMP signaling pathway hsa04080 Neuroactive ligand hsa04270 Vascular smooth muscle contractio hsa05012 Parkinson's disease

transmembrane receptor protein tyrosine kinase signaling pathway

adenylate cyclase-modulating G-protein coupled receptor signaling pathwayadenylate cyclase-activating G-protein coupled receptor signaling pathway

protein kinase C-activating G-protein coupled receptor signaling pathway

positive regulation of cAMP biosynthetic process

positive regulation of synaptic transmission, GABAergic

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

negative regulation of neuron apoptotic processnegative regulation of alpha-beta T cell activation

regulation of mitochondrial membrane potential

positive regulation of synaptic transmission, glutamatergicregulation of excitatory postsynaptic membrane potentialregulation of inhibitory postsynaptic membrane potential

positive regulation of apoptotic signaling pathway17 hsa04972 Pancreatic secretion

hsa04976 Bile secretion hsa04022 cGMP-PKG signaling pathway hsa04024 cAMP signaling pathway hsa04260 Cardiac muscle contraction hsa04261 Adrenergic signaling in cardiomyocytes hsa04911 Insulin secretion hsa04918 Thyroid hormone synthesis hsa04919 Thyroid hormone signaling pathway

negative regulation of glucocorticoid biosynthetic process hsa04960 Aldosterone-regulated sodium reabsorption hsa04961 Endocrine and other factor-regulated calcium reabsorption hsa04964 Proximal tubule bicarbonate reclamation hsa04970 Salivary secretion hsa04971 Gastric acid secretion

positive regulation of striated muscle contraction hsa04973 Carbohydrate digestion and absorption hsa04974 Protein digestion and absorption hsa04978 Mineral absorption

22 hsa04064 NF-kappa B signaling pathway hsa05145 Toxoplasmosis hsa04215 Apoptosis - multiple species hsa04141 Protein processing in endoplasmic reticulum hsa04340 Hedgehog signaling pathway hsa05161 Hepatitis B

hsa04630 Jak-STAT signaling pathway hsa05014 Amyotrophic lateral sclerosis (ALS)

branching involved in ureteric bud morphogenesis hsa05212 Pancreatic cancer hsa05220 Chronic myeloid leukemia hsa05222 Small cell lung cancer hsa05169 Epstein-Barr virus infection hsa05215 Prostate cancer hsa04066 HIF-1 signaling pathway hsa04071 Sphingolipid signaling pathway hsa04261 Adrenergic signaling in cardiomyocytes hsa04510 Focal adhesion hsa04722 Neurotrophin signaling pathway hsa04725 Cholinergic synapse hsa04933 AGE-RAGE signaling pathway in diabetic complications hsa05152 Tuberculosis hsa05210 Colorectal cancer

negative regulation of calcium ion transport into cytosolregulation of glycoprotein biosynthetic process

positive regulation of smooth muscle cell migration

regulation of transmembrane transporter activity

endoplasmic reticulum calcium ion homeostasis

negative regulation of myeloid cell apoptotic process

positive regulation of peptidyl-serine phosphorylationnegative regulation of osteoblast proliferation

nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway

positive regulation of multicellular organism growth

CD8-positive, alpha-beta T cell lineage commitment

regulation of protein homodimerization activityregulation of protein heterodimerization activitynegative regulation of neuron apoptotic process

positive regulation of melanocyte differentiation

negative regulation of retinal cell programmed cell deathregulation of mitochondrial membrane permeability

positive regulation of developmental pigmentation

positive regulation of skeletal muscle fiber development

homeostasis of number of cells within a tissue

regulation of mitochondrial membrane potentialnegative regulation of mitochondrial depolarization

intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress

positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway

negative regulation of apoptotic signaling pathwaypositive regulation of intrinsic apoptotic signaling pathway

4 hsa04723 Retrograde endocannabinoid signaling hsa04080 Neuroactive ligand-receptor interaction hsa04015 Rap1 signaling pathway

G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide hsa04024 cAMP signaling pathway adenylate cyclase-modulating G-protein coupled receptor signaling pathway

positive regulation of neuron projection development

negative regulation of fatty acid beta-oxidationregulation of synaptic transmission, GABAergic

negative regulation of nitric-oxide synthase activityregulation of synaptic transmission, glutamatergicmaternal process involved in female pregnancy

10 hsa05032 Morphine addiction hsa05030 Cocaine addiction hsa05031 Amphetamine addiction hsa05034 Alcoholism hsa04540 Gap junction hsa04020 Calcium signaling pathway hsa04024 cAMP signaling pathway hsa04080 Neuroactive ligand-receptor interaction

G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide hsa04728 Dopaminergic synapse adenylate cyclase-activating G-protein coupled receptor signaling pathway hsa05012 Parkinson's disease

adenylate cyclase-activating dopamine receptor signaling pathway

positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway

cerebral cortex GABAergic interneuron migration

positive regulation of cAMP biosynthetic process

positive regulation of release of sequestered calcium ion into cytosolelevation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathwayregulation of dopamine uptake involved in synaptic transmissionpositive regulation of synaptic transmission, glutamatergic

phospholipase C-activating dopamine receptor signaling pathway

15 hsa05031 Amphetamine addiction hsa04080 Neuroactive ligand-receptor interaction hsa04713 Circadian entrainment hsa05033 Nicotine addiction hsa05034 Alcoholism hsa04014 Ras signaling pathway hsa04015 Rap1 signaling pathway

hsa04020 Calcium signaling pathway hsa04024 cAMP signaling pathway hsa04720 Long-term potentiation hsa04724 Glutamatergic synapse hsa05010 Alzheimer's disease hsa05014 Amyotrophic lateral sclerosis (ALS) hsa05016 Huntington's disease hsa05030 Cocaine addiction

ionotropic glutamate receptor signaling pathway

negative regulation of neuron apoptotic process


regulation of long-term neuronal synaptic plasticity

regulation of excitatory postsynaptic membrane potential

positive regulation of excitatory postsynaptic membrane potential16 hsa05031 Amphetamine addiction

hsa04080 Neuroactive ligand-receptor interaction hsa04713 Circadian entrainment hsa05033 Nicotine addiction hsa05034 Alcoholism hsa04014 Ras signaling pathway hsa04015 Rap1 signaling pathway hsa04020 Calcium signaling pathway hsa04024 cAMP signaling pathway hsa04720 Long-term potentiation hsa04724 Glutamatergic synapse hsa04728 Dopaminergic synapse hsa05010 Alzheimer's disease hsa05014 Amyotrophic lateral sclerosis (ALS) hsa05030 Cocaine addiction hsa05322 Systemic lupus erythematosus

negative regulation of protein catabolic process

regulation of postsynaptic membrane potentialregulation of excitatory postsynaptic membrane potential

13 hsa05034 Alcoholism hsa05203 Viral carcinogenesis hsa05202 Transcriptional misregulation in cancer hsa05031 Amphetamine addiction

transcription initiation from RNA polymerase II promoter hsa05169 Epstein-Barr virus infection hsa05206 MicroRNAs in cancer

transforming growth factor beta receptor signaling pathway hsa04110 Cell cycle hsa04213 Longevity regulating pathway - multiple species hsa04330 Notch signaling pathway hsa04919 Thyroid hormone signaling pathway hsa05016 Huntington's disease hsa05200 Pathways in cancer

positive regulation of receptor biosynthetic process hsa05220 Chronic myeloid leukemia

negative regulation by host of viral transcription

negative regulation of transcription, DNA-dependentpositive regulation of transcription, DNA-dependentpositive regulation of transcription from RNA polymerase II promoter

negative regulation of androgen receptor signaling pathway

11 hsa05202 Transcriptional misregulation in cancer hsa04110 Cell cycle hsa04213 Longevity regulating pathway - multiple species hsa04330 Notch signaling pathway hsa04919 Thyroid hormone signaling pathway hsa05016 Huntington's disease hsa05034 Alcoholism hsa05169 Epstein-Barr virus infection

positive regulation of receptor biosynthetic process hsa05200 Pathways in cancer negative regulation of neuron projection development hsa05203 Viral carcinogenesis

hsa05220 Chronic myeloid leukemia

positive regulation of collagen biosynthetic process

negative regulation of sequence-specific DNA binding transcription factor activitynegative regulation of MHC class II biosynthetic process

negative regulation of transcription, DNA-dependentpositive regulation of transcription, DNA-dependentpositive regulation of transcription from RNA polymerase II promoter

positive regulation of oligodendrocyte differentiationpositive regulation of sequence-specific DNA binding transcription factor activityregulation of protein kinase B signaling cascade

negative regulation of cardiac muscle cell proliferation

negative regulation of canonical Wnt receptor signaling pathway

3 hsa04919 Thyroid hormone signaling pathway negative regulation of transcription from RNA polymerase II promoter hsa05034 Alcoholism

hsa05203 Viral carcinogenesis

negative regulation of transcription, DNA-dependent

71 hsa04723 Retrograde endocannabinoid signaling hsa05205 Proteoglycans in cancer hsa04071 Sphingolipid signaling pathway hsa04550 Signaling pathways regulating pluripotency of stem cells hsa04010 MAPK signaling pathway

MyD88-dependent toll-like receptor signaling pathway hsa04068 FoxO signaling pathway MyD88-independent toll-like receptor signaling pathway hsa04261 Adrenergic signaling in cardiomyocytes

hsa04380 Osteoclast differentiation hsa04620 Toll-like receptor signaling pathway hsa04621 NOD-like receptor signaling pathway hsa04722 Neurotrophin signaling pathway hsa04914 Progesterone-mediated oocyte maturation hsa04917 Prolactin signaling pathway hsa05131 Shigellosis hsa05145 Toxoplasmosis hsa05152 Tuberculosis

epidermal growth factor receptor signaling pathway hsa04015 Rap1 signaling pathway hsa04660 T cell receptor signaling pathway hsa05140 Leishmaniasis hsa05161 Hepatitis B hsa05206 MicroRNAs in cancer hsa04930 Type II diabetes mellitus

hsa04014 Ras signaling pathway hsa04024 cAMP signaling pathway

fibroblast growth factor receptor signaling pathway hsa04114 Oocyte meiosis hsa04360 Axon guidance hsa04510 Focal adhesion

positive regulation of peptidyl-threonine phosphorylation hsa04713 Circadian entrainment hsa04725 Cholinergic synapse hsa04726 Serotonergic synapse hsa04915 Estrogen signaling pathway hsa04921 Oxytocin signaling pathway hsa05034 Alcoholism hsa05212 Pancreatic cancer

lipopolysaccharide-mediated signaling pathway hsa05214 Glioma hsa05216 Thyroid cancer hsa05231 Choline metabolism in cancer hsa04022 cGMP-PKG signaling pathway hsa04062 Chemokine signaling pathway hsa04066 HIF-1 signaling pathway hsa04072 Phospholipase D signaling pathway hsa04150 mTOR signaling pathway hsa04151 PI3K-Akt signaling pathway hsa04270 Vascular smooth muscle contraction hsa04320 Dorso-ventral axis formation

TRIF-dependent toll-like receptor signaling pathway hsa04350 TGF-beta signaling pathway Fc-gamma receptor signaling pathway involved in phagocytosis hsa04520 Adherens junction toll-like receptor TLR1:TLR2 signaling pathway hsa04540 Gap junction toll-like receptor TLR6:TLR2 signaling pathway hsa04650 Natural killer cell mediated cytotoxicity

hsa04662 B cell receptor signaling pathway hsa04666 Fc gamma R-mediated phagocytosis hsa04720 Long-term potentiation hsa04724 Glutamatergic synapse hsa04730 Long-term depression hsa04810 Regulation of actin cytoskeleton hsa04916 Melanogenesis

positive regulation of transcription, DNA-dependent hsa04919 Thyroid hormone signaling pathway hsa04920 Adipocytokine signaling pathway hsa04960 Aldosterone-regulated sodium reabsorption hsa05010 Alzheimer's disease

regulation of sequence-specific DNA binding transcription factor activity hsa05020 Prion diseases hsa05203 Viral carcinogenesis hsa05211 Renal cell carcinoma

JAK-STAT cascade involved in growth hormone signaling pathway hsa05213 Endometrial cancer hsa05215 Prostate cancer hsa05218 Melanoma hsa05219 Bladder cancer hsa05220 Chronic myeloid leukemia

hsa05221 Acute myeloid leukemia regulation of early endosome to late endosome transport hsa05223 Non-small cell lung cancer

hsa05230 Central carbon metabolism in cancer negative regulation of transcription from RNA polymerase II promoter hsa05161 Hepatitis B

hsa04064 NF-kappa B signaling pathway hsa04668 TNF signaling pathway

MyD88-dependent toll-like receptor signaling pathway hsa05203 Viral carcinogenesis MyD88-independent toll-like receptor signaling pathway hsa05321 Inflammatory bowel disease (IBD)

hsa04620 Toll-like receptor signaling pathway transcription from RNA polymerase II promoter hsa04623 Cytosolic DNA-sensing pathway

hsa04722 Neurotrophin signaling pathway hsa04931 Insulin resistance hsa04932 Non-alcoholic fatty liver disease (NAFLD) hsa05142 Chagas disease (American trypanosomiasis) hsa05146 Amoebiasis

positive regulation of macrophage derived foam cell differentiation hsa05160 Hepatitis C hsa05166 HTLV-I infection

negative regulation of calcidiol 1-monooxygenase activity hsa05168 Herpes simplex infection negative regulation of vitamin D biosynthetic process hsa05169 Epstein-Barr virus infection membrane protein intracellular domain proteolysis hsa05212 Pancreatic cancer negative regulation of cellular protein metabolic process hsa05206 MicroRNAs in cancer

hsa04010 MAPK signaling pathway positive regulation of type I interferon production hsa04014 Ras signaling pathway

hsa04024 cAMP signaling pathway hsa04062 Chemokine signaling pathway hsa04066 HIF-1 signaling pathway hsa04071 Sphingolipid signaling pathway hsa04151 PI3K-Akt signaling pathway hsa04210 Apoptosis

TRIF-dependent toll-like receptor signaling pathway hsa04211 Longevity regulating pathway toll-like receptor TLR1:TLR2 signaling pathway hsa04380 Osteoclast differentiation toll-like receptor TLR6:TLR2 signaling pathway hsa04621 NOD-like receptor signaling pathway

hsa04622 RIG-I-like receptor signaling pathway negative regulation of interleukin-12 biosynthetic process hsa04660 T cell receptor signaling pathway

hsa04662 B cell receptor signaling pathway negative regulation of transcription, DNA-dependent hsa04917 Prolactin signaling pathway positive regulation of transcription, DNA-dependent hsa04920 Adipocytokine signaling pathway positive regulation of transcription from RNA polymerase II promoter hsa04933 AGE-RAGE signaling pathway in diabetic complications

hsa05030 Cocaine addiction hsa05120 Epithelial cell signaling in Helicobacter pylori infection hsa05131 Shigellosis hsa05132 Salmonella infection

positive regulation of NF-kappaB transcription factor activity hsa05133 Pertussis hsa05134 Legionellosis hsa05140 Leishmaniasis

positive regulation of canonical Wnt receptor signaling pathway hsa05145 Toxoplasmosis

positive regulation of hyaluronan biosynthetic process hsa05152 Tuberculosis hsa05162 Measles hsa05164 Influenza A hsa05200 Pathways in cancer hsa05202 Transcriptional misregulation in cancer hsa05215 Prostate cancer hsa05220 Chronic myeloid leukemia hsa05221 Acute myeloid leukemia hsa05222 Small cell lung cancer

5 hsa04020 Calcium signaling pathway generation of precursor metabolites and energy hsa04022 cGMP-PKG signaling pathway

hsa05012 Parkinson's disease hsa05016 Huntington's disease hsa05166 HTLV-I infection

2 hsa04721 Synaptic vesicle cycle hsa04911 Insulin secretion

synaptic vesicle docking involved in exocytosis

3 hsa04145 Phagosome - Homo sapiens (human)hsa04540 Gap junction - Homo sapiens (human)hsa05130 Pathogenic Escherichia coli infection - Homo sapiens (human)

cytoskeleton-dependent intracellular transport

15 hsa04213 Longevity regulating pathway - multiple species - Homo sapiens (human)hsa04920 Adipocytokine signaling pathway - Homo sapiens (human)hsa04068 FoxO signaling pathway - Homo sapiens (human)hsa04140 Regulation of autophagy - Homo sapiens (human)hsa04150 mTOR signaling pathway - Homo sapiens (human)hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human)hsa04152 AMPK signaling pathway - Homo sapiens (human)hsa04211 Longevity regulating pathway - Homo sapiens (human)

hsa04710 Circadian rhythm - Homo sapiens (human)hsa04910 Insulin signaling pathway - Homo sapiens (human)hsa04921 Oxytocin signaling pathway - Homo sapiens (human)hsa04922 Glucagon signaling pathway - Homo sapiens (human)hsa04931 Insulin resistance - Homo sapiens (human)hsa04932 Non-alcoholic fatty liver disease (NAFLD) - Homo sapiens (human)hsa05410 Hypertrophic cardiomyopathy (HCM) - Homo sapiens (human)

positive regulation of cholesterol biosynthetic process

negative regulation of glucosylceramide biosynthetic process

negative regulation of glucose import in response to insulin stimulus

Vascular smooth muscle contraction - Homo sapiens (human)

cGMP-PKG signaling pathway - Homo sapiens (human)Phosphatidylinositol signaling system - Homo sapiens (human)

Retrograde endocannabinoid signaling - Homo sapiens (human)

Inflammatory mediator regulation of TRP channels - Homo sapiens (human)

Aldosterone synthesis and secretion - Homo sapiens (human)

NF-kappa B signaling pathway - Homo sapiens (human)

Transcriptional misregulation in cancer - Homo sapiens (human)

cGMP-PKG signaling pathway - Homo sapiens (human)

Phosphatidylinositol signaling system - Homo sapiens (human)

Adrenergic signaling in cardiomyocytes - Homo sapiens (human)Vascular smooth muscle contraction - Homo sapiens (human)

Neurotrophin signaling pathway - Homo sapiens (human)

Inflammatory mediator regulation of TRP channels - Homo sapiens (human)

Aldosterone synthesis and secretion - Homo sapiens (human)

Bacterial invasion of epithelial cells - Homo sapiens (human)

Valine, leucine and isoleucine degradation - Homo sapiens (human)

Glycolysis / Gluconeogenesis - Homo sapiens (human)Glycine, serine and threonine metabolism - Homo sapiens (human)

Glyoxylate and dicarboxylate metabolism - Homo sapiens (human)

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis Epithelial cell signaling in Helicobacter pylori infection

Endocrine and other factor-regulated calcium reabsorption

Signaling pathways regulating pluripotency of stem cells

AGE-RAGE signaling pathway in diabetic complications

Endocrine and other factor-regulated calcium reabsorption

Signaling pathways regulating pluripotency of stem cells


Epithelial cell signaling in Helicobacter pylori infection

Pathogenic Escherichia coli infection - Homo sapiens (human)

Longevity regulating pathway - multiple species - Homo sapiens (human)Adipocytokine signaling pathway - Homo sapiens (human)

Longevity regulating pathway - Homo sapiens (human)

Non-alcoholic fatty liver disease (NAFLD) - Homo sapiens (human)Hypertrophic cardiomyopathy (HCM) - Homo sapiens (human)

PDE1A PHACTR4 POLR2B PPEF1 PPEF2

ELL EP300 EPHA3 ERCC2 ERCC3

PPIL2 PRDX1 PSMD12 PSMD2 PTPRA RAD23B RAF1 RALA RALB

ERCC6 ERH ESR1 ETHE1 FAM173A FBXO11 FBXO42 FKBP3 FXYD6

RANBP2 RCHY1 RDX RIT2 RPL13A RPL22 RPS14 RPS15A RPS4Y1

G3BP1 G3BP2 GADD45A GNL3 GNL3L GPS2 GSK3B GSTM4 GTF2H1

RPS8 S100B SCAPER SCLT1 SCN5A SET SF3B1 SLC9A1 SLTM

GTPBP4 H2AFX HABP4 HDAC1 HDAC2 HDAC5 HDAC9 HECW2 HIF1A

SLX1B SNCA SNRPB2 SNX6 SQSTM1 SRP14 SRSF5 STAG1 STIM2

HIPK1 HIPK2 HIPK3 HMGA1 HMGB1 HNF4A HSP90AA1 HSPA1A HSPA4

STX8 SYK SYNE2 SYT1 TCF3 TCF4 TGM2 THOP1 TPT1

HSPA5 HSPA8 HSPA9 HSPB1 HTT HUWE1 IFI16 IGF1R IGF2BP1

TRDN TRPV1 TRPV6 UBC UBE3A UCHL5 USP16 USP20 XRCC4

IKBKB ING1 ING2 ING4 ING5 ITCH KAT2A KAT2B KAT5

YBX1 YWHAE YWHAQ ZBTB24

KAT6A KAT7 KAT8 KDM1A KIAA0087 KIAA1267 KPNA4 KPNB1 L3MBTL1

LAMA4 LOC613037LRPPRC MAD2L1BPMAFK MAGEA2 MAGEB18 MAPK1 MAPK10

MAPK3 MAPK8 MAPK9 MDC1 MDH1 MDM2 MDM4 MED1 MED17

MED21 MEN1 MLL MLL5 MNAT1 MPHOSPH6MSH2 MSH6 MSL2

MTA1 MTA2 MTHFSD MYL9 NCL NCOR1 NDN NEDD8 NFKBIA

NFYA NFYB NOC2L NOTCH4 NPM1 NPRL3 NQO2 NR3C1 NR4A1

NUB1 NUMB OTUD5 PADI4 PAFAH1B3 PARP1 PCDHA4 PDLIM7 PHF1

PIAS1 PIAS2 PIN1 PIWIL1 PLAGL1 PLK3 PML PNP POLA1

PPA1 PPP1R13L PPP4C PRAM1 PRDM2 PRKDC PRKRA PRKRIR PRMT1

PRMT3 PSMC3 PSMC5 PSMD10 PSMD11 PSMD4 PSME3 PTEN PTGS2

PTK2 PTTG1 RAB4A RAD23A RAD51 RAP1B RB1CC1 RBBP5 RCC1

RCHY1 RFC1 RFFL RFWD2 RFWD3 RNF20 RNF34 RNF38 RPA1

RPL11 RPL23 RPL26 RPL5 RPS3 RPS7 RRM2 RRM2B RYBP

RYK S100A4 S100A8 S100B 06/01/15 SENP3 SERBP1 SERPINB9 SERPINH1

SETD2 SETD7 SETD8 SFN SIN3A SIN3B SIRT1 SIVA1 SKI

SMAD2 SMAD3 SMARCA4 SMARCB1 SMARCC1 SMARCD2 SMN1 SMURF1 SMYD2

SNRPN SOX4 SP1 SP3 SPSB1 STAT6 STK11 STUB1 STX5

SULT1E1 SUMO1 SUMO2 SUMO3 SUPT3H SUPT7L SYVN1 TADA1 TADA2A

TADA3 TAF1 TAF10 TAF1A TAF1B TAF1C TAF5L TAF6 TAF9

TAG TBP TDG TEP1 TFAP2A TFAP2C TFDP1 THAP8 THRB

TK1 TOP1 TOP2A TOP2B TOPORS TP53 TP53 TP53BP1 TP53BP2

TP53INP1 TP53RK TPT1 TRIAP1 TRIM24 TRIM27 TRIM28 TRMT11 TRRAP

TSG101 TTK TTLL5 TXN UBC UBE2A UBE2I UBE2N UBE3A

UBE4B UBR5 UCHL1 UFD1L UHRF2 UIMC1 USO1 USP10 USP11

USP29 USP39 USP42 USP7 UTP14A VDR VHL VRK1 VRK2

WDR33 WDR48 WDR5 WRN WT1 WWOX XRCC1 XRCC6 YBX1

YWHAZ YY1 ZBTB2 ZBTB7A ZCCHC10 ZMIZ1 ZMIZ2 ZMYND11 ZNF148

ZNF24 ZNF420 ZNF668 ZNHIT1

Supplementary Table S9B: Biological Processes and KEGG pathways connected with HD associated genes without TVS and targets of FDA approved drugs or potential targets o f drugsGene symbol DescriptionADAR adenosine deaminase, RNA-specific [Source:HGNC Symbol;Acc:225]ADAR adenosine deaminase, RNA-specific [Source:HGNC Symbol;Acc:225]ADAR adenosine deaminase, RNA-specific [Source:HGNC Symbol;Acc:225]ADAR adenosine deaminase, RNA-specific [Source:HGNC Symbol;Acc:225]ADAR adenosine deaminase, RNA-specific [Source:HGNC Symbol;Acc:225]ADAR adenosine deaminase, RNA-specific [Source:HGNC Symbol;Acc:225]ADAR adenosine deaminase, RNA-specific [Source:HGNC Symbol;Acc:225]ADAR adenosine deaminase, RNA-specific [Source:HGNC Symbol;Acc:225]ADAR adenosine deaminase, RNA-specific [Source:HGNC Symbol;Acc:225]ADAR adenosine deaminase, RNA-specific [Source:HGNC Symbol;Acc:225]ADAR adenosine deaminase, RNA-specific [Source:HGNC Symbol;Acc:225]ADAR adenosine deaminase, RNA-specific [Source:HGNC Symbol;Acc:225]ADAR adenosine deaminase, RNA-specific [Source:HGNC Symbol;Acc:225]ADAR adenosine deaminase, RNA-specific [Source:HGNC Symbol;Acc:225]ADAR adenosine deaminase, RNA-specific [Source:HGNC Symbol;Acc:225]ADAR adenosine deaminase, RNA-specific [Source:HGNC Symbol;Acc:225]ADAR adenosine deaminase, RNA-specific [Source:HGNC Symbol;Acc:225]ADAR adenosine deaminase, RNA-specific [Source:HGNC Symbol;Acc:225]ALDOA aldolase A, fructose-bisphosphate [Source:HGNC Symbol;Acc:414]ALDOA aldolase A, fructose-bisphosphate [Source:HGNC Symbol;Acc:414]ALDOA aldolase A, fructose-bisphosphate [Source:HGNC Symbol;Acc:414]ALDOA aldolase A, fructose-bisphosphate [Source:HGNC Symbol;Acc:414]ALDOA aldolase A, fructose-bisphosphate [Source:HGNC Symbol;Acc:414]ALDOA aldolase A, fructose-bisphosphate [Source:HGNC Symbol;Acc:414]ALDOA aldolase A, fructose-bisphosphate [Source:HGNC Symbol;Acc:414]ALDOA aldolase A, fructose-bisphosphate [Source:HGNC Symbol;Acc:414]ALDOA aldolase A, fructose-bisphosphate [Source:HGNC Symbol;Acc:414]ALDOA aldolase A, fructose-bisphosphate [Source:HGNC Symbol;Acc:414]ALDOA aldolase A, fructose-bisphosphate [Source:HGNC Symbol;Acc:414]ALDOA aldolase A, fructose-bisphosphate [Source:HGNC Symbol;Acc:414]ALDOA aldolase A, fructose-bisphosphate [Source:HGNC Symbol;Acc:414]ALDOA aldolase A, fructose-bisphosphate [Source:HGNC Symbol;Acc:414]ALDOA aldolase A, fructose-bisphosphate [Source:HGNC Symbol;Acc:414]ALDOA aldolase A, fructose-bisphosphate [Source:HGNC Symbol;Acc:414]APP amyloid beta (A4) precursor protein [Source:HGNC Symbol;Acc:620]APP amyloid beta (A4) precursor protein [Source:HGNC Symbol;Acc:620]APP amyloid beta (A4) precursor protein [Source:HGNC Symbol;Acc:620]APP amyloid beta (A4) precursor protein [Source:HGNC Symbol;Acc:620]APP amyloid beta (A4) precursor protein [Source:HGNC Symbol;Acc:620]APP amyloid beta (A4) precursor protein [Source:HGNC Symbol;Acc:620]APP amyloid beta (A4) precursor protein [Source:HGNC Symbol;Acc:620]APP amyloid beta (A4) precursor protein [Source:HGNC Symbol;Acc:620]APP amyloid beta (A4) precursor protein [Source:HGNC Symbol;Acc:620]APP amyloid beta (A4) precursor protein [Source:HGNC Symbol;Acc:620]

APP amyloid beta (A4) precursor protein [Source:HGNC Symbol;Acc:620]APP amyloid beta (A4) precursor protein [Source:HGNC Symbol;Acc:620]APP amyloid beta (A4) precursor protein [Source:HGNC Symbol;Acc:620]APP amyloid beta (A4) precursor protein [Source:HGNC Symbol;Acc:620]APP amyloid beta (A4) precursor protein [Source:HGNC Symbol;Acc:620]APP amyloid beta (A4) precursor protein [Source:HGNC Symbol;Acc:620]APP amyloid beta (A4) precursor protein [Source:HGNC Symbol;Acc:620]APP amyloid beta (A4) precursor protein [Source:HGNC Symbol;Acc:620]APP amyloid beta (A4) precursor protein [Source:HGNC Symbol;Acc:620]APP amyloid beta (A4) precursor protein [Source:HGNC Symbol;Acc:620]APP amyloid beta (A4) precursor protein [Source:HGNC Symbol;Acc:620]APP amyloid beta (A4) precursor protein [Source:HGNC Symbol;Acc:620]APP amyloid beta (A4) precursor protein [Source:HGNC Symbol;Acc:620]APP amyloid beta (A4) precursor protein [Source:HGNC Symbol;Acc:620]APP amyloid beta (A4) precursor protein [Source:HGNC Symbol;Acc:620]APP amyloid beta (A4) precursor protein [Source:HGNC Symbol;Acc:620]APP amyloid beta (A4) precursor protein [Source:HGNC Symbol;Acc:620]APP amyloid beta (A4) precursor protein [Source:HGNC Symbol;Acc:620]APP amyloid beta (A4) precursor protein [Source:HGNC Symbol;Acc:620]APP amyloid beta (A4) precursor protein [Source:HGNC Symbol;Acc:620]APP amyloid beta (A4) precursor protein [Source:HGNC Symbol;Acc:620]APP amyloid beta (A4) precursor protein [Source:HGNC Symbol;Acc:620]APP amyloid beta (A4) precursor protein [Source:HGNC Symbol;Acc:620]APP amyloid beta (A4) precursor protein [Source:HGNC Symbol;Acc:620]APP amyloid beta (A4) precursor protein [Source:HGNC Symbol;Acc:620]APP amyloid beta (A4) precursor protein [Source:HGNC Symbol;Acc:620]APP amyloid beta (A4) precursor protein [Source:HGNC Symbol;Acc:620]APP amyloid beta (A4) precursor protein [Source:HGNC Symbol;Acc:620]APP amyloid beta (A4) precursor protein [Source:HGNC Symbol;Acc:620]APP amyloid beta (A4) precursor protein [Source:HGNC Symbol;Acc:620]APP amyloid beta (A4) precursor protein [Source:HGNC Symbol;Acc:620]APP amyloid beta (A4) precursor protein [Source:HGNC Symbol;Acc:620]APP amyloid beta (A4) precursor protein [Source:HGNC Symbol;Acc:620]APP amyloid beta (A4) precursor protein [Source:HGNC Symbol;Acc:620]APP amyloid beta (A4) precursor protein [Source:HGNC Symbol;Acc:620]ASNS asparagine synthetase (glutamine-hydrolyzing) [Source:HGNC Symbol;Acc:75ASNS asparagine synthetase (glutamine-hydrolyzing) [Source:HGNC Symbol;Acc:753]ASNS asparagine synthetase (glutamine-hydrolyzing) [Source:HGNC Symbol;Acc:753]ASNS asparagine synthetase (glutamine-hydrolyzing) [Source:HGNC Symbol;Acc:753]ASNS asparagine synthetase (glutamine-hydrolyzing) [Source:HGNC Symbol;Acc:753]ASNS asparagine synthetase (glutamine-hydrolyzing) [Source:HGNC Symbol;Acc:753]ASNS asparagine synthetase (glutamine-hydrolyzing) [Source:HGNC Symbol;Acc:753]ASNS asparagine synthetase (glutamine-hydrolyzing) [Source:HGNC Symbol;Acc:753]ASNS asparagine synthetase (glutamine-hydrolyzing) [Source:HGNC Symbol;Acc:753]ASNS asparagine synthetase (glutamine-hydrolyzing) [Source:HGNC Symbol;Acc:753]ASNS asparagine synthetase (glutamine-hydrolyzing) [Source:HGNC Symbol;Acc:753]

ASNS asparagine synthetase (glutamine-hydrolyzing) [Source:HGNC Symbol;Acc:753]ASNS asparagine synthetase (glutamine-hydrolyzing) [Source:HGNC Symbol;Acc:753]ASNS asparagine synthetase (glutamine-hydrolyzing) [Source:HGNC Symbol;Acc:753]ASNS asparagine synthetase (glutamine-hydrolyzing) [Source:HGNC Symbol;Acc:753]ASNS asparagine synthetase (glutamine-hydrolyzing) [Source:HGNC Symbol;Acc:753]ASNS asparagine synthetase (glutamine-hydrolyzing) [Source:HGNC Symbol;Acc:753]ASNS asparagine synthetase (glutamine-hydrolyzing) [Source:HGNC Symbol;Acc:753]ASNS asparagine synthetase (glutamine-hydrolyzing) [Source:HGNC Symbol;Acc:753]ASNS asparagine synthetase (glutamine-hydrolyzing) [Source:HGNC Symbol;Acc:753]ASNS asparagine synthetase (glutamine-hydrolyzing) [Source:HGNC Symbol;Acc:753]ASNS asparagine synthetase (glutamine-hydrolyzing) [Source:HGNC Symbol;Acc:753]ASNS asparagine synthetase (glutamine-hydrolyzing) [Source:HGNC Symbol;Acc:753]ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 [Source:HGNC SymATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 [Source:HGNC Symbol;Acc:812]ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 [Source:HGNC Symbol;Acc:812]ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 [Source:HGNC Symbol;Acc:812]ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 [Source:HGNC Symbol;Acc:812]ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 [Source:HGNC Symbol;Acc:812]ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 [Source:HGNC Symbol;Acc:812]ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 [Source:HGNC Symbol;Acc:812]ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 [Source:HGNC Symbol;Acc:812]ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 [Source:HGNC Symbol;Acc:812]ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 [Source:HGNC Symbol;Acc:812]ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 [Source:HGNC Symbol;Acc:812]ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 [Source:HGNC Symbol;Acc:812]ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 [Source:HGNC Symbol;Acc:812]ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 [Source:HGNC Symbol;Acc:812]ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 [Source:HGNC Symbol;Acc:812]BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) [SourceBAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) [Source:HGNC Symbol;Acc:950]BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) [Source:HGNC Symbol;Acc:950]BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) [Source:HGNC Symbol;Acc:950]BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) [Source:HGNC Symbol;Acc:950]BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) [Source:HGNC Symbol;Acc:950]BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) [Source:HGNC Symbol;Acc:950]BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) [Source:HGNC Symbol;Acc:950]BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) [Source:HGNC Symbol;Acc:950]BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) [Source:HGNC Symbol;Acc:950]BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) [Source:HGNC Symbol;Acc:950]BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) [Source:HGNC Symbol;Acc:950]BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) [Source:HGNC Symbol;Acc:950]BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) [Source:HGNC Symbol;Acc:950]BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) [Source:HGNC Symbol;Acc:950]BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) [Source:HGNC Symbol;Acc:950]BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) [Source:HGNC Symbol;Acc:950]BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) [Source:HGNC Symbol;Acc:950]

BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) [Source:HGNC Symbol;Acc:950]BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) [Source:HGNC Symbol;Acc:950]BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) [Source:HGNC Symbol;Acc:950]BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) [Source:HGNC Symbol;Acc:950]BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) [Source:HGNC Symbol;Acc:950]BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) [Source:HGNC Symbol;Acc:950]BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) [Source:HGNC Symbol;Acc:950]BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) [Source:HGNC Symbol;Acc:950]BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) [Source:HGNC Symbol;Acc:950]BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) [Source:HGNC Symbol;Acc:950]BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) [Source:HGNC Symbol;Acc:950]BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) [Source:HGNC Symbol;Acc:950]BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) [Source:HGNC Symbol;Acc:950]BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) [Source:HGNC Symbol;Acc:950]CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) [SourCASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) [Source:HGNC Symbol;Acc:14CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) [Source:HGNC Symbol;Acc:14CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) [Source:HGNC Symbol;Acc:14CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) [Source:HGNC Symbol;Acc:14CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) [Source:HGNC Symbol;Acc:14CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) [Source:HGNC Symbol;Acc:14CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) [Source:HGNC Symbol;Acc:14CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) [Source:HGNC Symbol;Acc:14CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) [Source:HGNC Symbol;Acc:1497]CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) [Source:HGNC Symbol;Acc:1497]CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) [Source:HGNC Symbol;Acc:1497]CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) [Source:HGNC Symbol;Acc:1497]CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) [Source:HGNC Symbol;Acc:1497]CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) [Source:HGNC Symbol;Acc:1497]CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) [Source:HGNC Symbol;Acc:1497]CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) [Source:HGNC Symbol;Acc:1497]CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) [Source:HGNC Symbol;Acc:1497]CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) [Source:HGNC Symbol;Acc:1497]CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) [Source:HGNC Symbol;Acc:1497]CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) [Source:HGNC Symbol;Acc:1497]CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) [Source:HGNC Symbol;Acc:1497]CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) [Source:HGNC Symbol;Acc:1497]CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) [Source:HGNC Symbol;Acc:1497]CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) [Source:HGNC Symbol;Acc:1497]CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) [Source:HGNC Symbol;Acc:1497]CASP10 caspase 10, apoptosis-related cysteine peptidase [Source:HGNC Symbol;Acc:CASP10 caspase 10, apoptosis-related cysteine peptidase [Source:HGNC Symbol;Acc:1500]CASP10 caspase 10, apoptosis-related cysteine peptidase [Source:HGNC Symbol;Acc:1500]CASP10 caspase 10, apoptosis-related cysteine peptidase [Source:HGNC Symbol;Acc:1500]CASP10 caspase 10, apoptosis-related cysteine peptidase [Source:HGNC Symbol;Acc:1500]CASP10 caspase 10, apoptosis-related cysteine peptidase [Source:HGNC Symbol;Acc:1500]

CASP10 caspase 10, apoptosis-related cysteine peptidase [Source:HGNC Symbol;Acc:1500]CASP10 caspase 10, apoptosis-related cysteine peptidase [Source:HGNC Symbol;Acc:1500]CASP10 caspase 10, apoptosis-related cysteine peptidase [Source:HGNC Symbol;Acc:1500]CASP10 caspase 10, apoptosis-related cysteine peptidase [Source:HGNC Symbol;Acc:1500]CASP10 caspase 10, apoptosis-related cysteine peptidase [Source:HGNC Symbol;Acc:1500]CASP10 caspase 10, apoptosis-related cysteine peptidase [Source:HGNC Symbol;Acc:1500]CASP10 caspase 10, apoptosis-related cysteine peptidase [Source:HGNC Symbol;Acc:1500]CASP10 caspase 10, apoptosis-related cysteine peptidase [Source:HGNC Symbol;Acc:1500]CASP10 caspase 10, apoptosis-related cysteine peptidase [Source:HGNC Symbol;Acc:1500]CASP10 caspase 10, apoptosis-related cysteine peptidase [Source:HGNC Symbol;Acc:1500]CHD8 chromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20CHD8 chromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20153]CHD8 chromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20153]CHD8 chromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20153]CHD8 chromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20153]CHD8 chromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20153]CHD8 chromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20153]CHD8 chromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20153]CHD8 chromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20153]CHD8 chromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20153]CHD8 chromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20153]CHD8 chromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20153]CHD8 chromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20153]CHD8 chromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20153]CHD8 chromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20153]CHD8 chromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20153]CHD8 chromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20153]CHD8 chromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20153]CHD8 chromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20153]CHD8 chromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20153]CHD8 chromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20153]CHD8 chromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20153]CHD8 chromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20153]CHD8 chromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20153]CHD8 chromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20153]CHD8 chromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20153]CHD8 chromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20153]CHD8 chromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20153]CHD8 chromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20153]CHD8 chromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20153]CHD8 chromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20153]CHD8 chromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20153]CHD8 chromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20153]CHD8 chromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20153]CHD8 chromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20153]CPT2 carnitine palmitoyltransferase 2 [Source:HGNC Symbol;Acc:2330]

CPT2 carnitine palmitoyltransferase 2 [Source:HGNC Symbol;Acc:2330]CPT2 carnitine palmitoyltransferase 2 [Source:HGNC Symbol;Acc:2330]CPT2 carnitine palmitoyltransferase 2 [Source:HGNC Symbol;Acc:2330]CPT2 carnitine palmitoyltransferase 2 [Source:HGNC Symbol;Acc:2330]CPT2 carnitine palmitoyltransferase 2 [Source:HGNC Symbol;Acc:2330]CPT2 carnitine palmitoyltransferase 2 [Source:HGNC Symbol;Acc:2330]CPT2 carnitine palmitoyltransferase 2 [Source:HGNC Symbol;Acc:2330]CPT2 carnitine palmitoyltransferase 2 [Source:HGNC Symbol;Acc:2330]CPT2 carnitine palmitoyltransferase 2 [Source:HGNC Symbol;Acc:2330]CPT2 carnitine palmitoyltransferase 2 [Source:HGNC Symbol;Acc:2330]CPT2 carnitine palmitoyltransferase 2 [Source:HGNC Symbol;Acc:2330]CPT2 carnitine palmitoyltransferase 2 [Source:HGNC Symbol;Acc:2330]CPT2 carnitine palmitoyltransferase 2 [Source:HGNC Symbol;Acc:2330]CPT2 carnitine palmitoyltransferase 2 [Source:HGNC Symbol;Acc:2330]CPT2 carnitine palmitoyltransferase 2 [Source:HGNC Symbol;Acc:2330]CPT2 carnitine palmitoyltransferase 2 [Source:HGNC Symbol;Acc:2330]CPT2 carnitine palmitoyltransferase 2 [Source:HGNC Symbol;Acc:2330]CPT2 carnitine palmitoyltransferase 2 [Source:HGNC Symbol;Acc:2330]CPT2 carnitine palmitoyltransferase 2 [Source:HGNC Symbol;Acc:2330]CPT2 carnitine palmitoyltransferase 2 [Source:HGNC Symbol;Acc:2330]CPT2 carnitine palmitoyltransferase 2 [Source:HGNC Symbol;Acc:2330]CPT2 carnitine palmitoyltransferase 2 [Source:HGNC Symbol;Acc:2330]CPT2 carnitine palmitoyltransferase 2 [Source:HGNC Symbol;Acc:2330]CTH cystathionase (cystathionine gamma-lyase) [Source:HGNC Symbol;Acc:2501]CTH cystathionase (cystathionine gamma-lyase) [Source:HGNC Symbol;Acc:2501]CTH cystathionase (cystathionine gamma-lyase) [Source:HGNC Symbol;Acc:2501]CTH cystathionase (cystathionine gamma-lyase) [Source:HGNC Symbol;Acc:2501]CTH cystathionase (cystathionine gamma-lyase) [Source:HGNC Symbol;Acc:2501]CTH cystathionase (cystathionine gamma-lyase) [Source:HGNC Symbol;Acc:2501]CTH cystathionase (cystathionine gamma-lyase) [Source:HGNC Symbol;Acc:2501]CTH cystathionase (cystathionine gamma-lyase) [Source:HGNC Symbol;Acc:2501]CTH cystathionase (cystathionine gamma-lyase) [Source:HGNC Symbol;Acc:2501]CTH cystathionase (cystathionine gamma-lyase) [Source:HGNC Symbol;Acc:2501]CTH cystathionase (cystathionine gamma-lyase) [Source:HGNC Symbol;Acc:2501]CTH cystathionase (cystathionine gamma-lyase) [Source:HGNC Symbol;Acc:2501]CTH cystathionase (cystathionine gamma-lyase) [Source:HGNC Symbol;Acc:2501]CTH cystathionase (cystathionine gamma-lyase) [Source:HGNC Symbol;Acc:2501]CTH cystathionase (cystathionine gamma-lyase) [Source:HGNC Symbol;Acc:2501]CTH cystathionase (cystathionine gamma-lyase) [Source:HGNC Symbol;Acc:2501]CTH cystathionase (cystathionine gamma-lyase) [Source:HGNC Symbol;Acc:2501]CTH cystathionase (cystathionine gamma-lyase) [Source:HGNC Symbol;Acc:2501]CTH cystathionase (cystathionine gamma-lyase) [Source:HGNC Symbol;Acc:2501]CTH cystathionase (cystathionine gamma-lyase) [Source:HGNC Symbol;Acc:2501]CTH cystathionase (cystathionine gamma-lyase) [Source:HGNC Symbol;Acc:2501]CTH cystathionase (cystathionine gamma-lyase) [Source:HGNC Symbol;Acc:2501]CTH cystathionase (cystathionine gamma-lyase) [Source:HGNC Symbol;Acc:2501]

CTH cystathionase (cystathionine gamma-lyase) [Source:HGNC Symbol;Acc:2501]CTNS cystinosin, lysosomal cystine transporter [Source:HGNC Symbol;Acc:2518]CTNS cystinosin, lysosomal cystine transporter [Source:HGNC Symbol;Acc:2518]CTNS cystinosin, lysosomal cystine transporter [Source:HGNC Symbol;Acc:2518]CTNS cystinosin, lysosomal cystine transporter [Source:HGNC Symbol;Acc:2518]CTNS cystinosin, lysosomal cystine transporter [Source:HGNC Symbol;Acc:2518]CTNS cystinosin, lysosomal cystine transporter [Source:HGNC Symbol;Acc:2518]CTNS cystinosin, lysosomal cystine transporter [Source:HGNC Symbol;Acc:2518]CTNS cystinosin, lysosomal cystine transporter [Source:HGNC Symbol;Acc:2518]CTNS cystinosin, lysosomal cystine transporter [Source:HGNC Symbol;Acc:2518]CTNS cystinosin, lysosomal cystine transporter [Source:HGNC Symbol;Acc:2518]CTNS cystinosin, lysosomal cystine transporter [Source:HGNC Symbol;Acc:2518]CTNS cystinosin, lysosomal cystine transporter [Source:HGNC Symbol;Acc:2518]CTNS cystinosin, lysosomal cystine transporter [Source:HGNC Symbol;Acc:2518]CTNS cystinosin, lysosomal cystine transporter [Source:HGNC Symbol;Acc:2518]CTNS cystinosin, lysosomal cystine transporter [Source:HGNC Symbol;Acc:2518]CTNS cystinosin, lysosomal cystine transporter [Source:HGNC Symbol;Acc:2518]CTNS cystinosin, lysosomal cystine transporter [Source:HGNC Symbol;Acc:2518]CTNS cystinosin, lysosomal cystine transporter [Source:HGNC Symbol;Acc:2518]CTNS cystinosin, lysosomal cystine transporter [Source:HGNC Symbol;Acc:2518]CTNS cystinosin, lysosomal cystine transporter [Source:HGNC Symbol;Acc:2518]EGFR epidermal growth factor receptor [Source:HGNC Symbol;Acc:3236]EGFR epidermal growth factor receptor [Source:HGNC Symbol;Acc:3236]EGFR epidermal growth factor receptor [Source:HGNC Symbol;Acc:3236]EGFR epidermal growth factor receptor [Source:HGNC Symbol;Acc:3236]EGFR epidermal growth factor receptor [Source:HGNC Symbol;Acc:3236]EGFR epidermal growth factor receptor [Source:HGNC Symbol;Acc:3236]EGFR epidermal growth factor receptor [Source:HGNC Symbol;Acc:3236]EGFR epidermal growth factor receptor [Source:HGNC Symbol;Acc:3236]EGFR epidermal growth factor receptor [Source:HGNC Symbol;Acc:3236]EGFR epidermal growth factor receptor [Source:HGNC Symbol;Acc:3236]EGFR epidermal growth factor receptor [Source:HGNC Symbol;Acc:3236]EGFR epidermal growth factor receptor [Source:HGNC Symbol;Acc:3236]EGFR epidermal growth factor receptor [Source:HGNC Symbol;Acc:3236]EGFR epidermal growth factor receptor [Source:HGNC Symbol;Acc:3236]EGFR epidermal growth factor receptor [Source:HGNC Symbol;Acc:3236]EGFR epidermal growth factor receptor [Source:HGNC Symbol;Acc:3236]EGFR epidermal growth factor receptor [Source:HGNC Symbol;Acc:3236]EGFR epidermal growth factor receptor [Source:HGNC Symbol;Acc:3236]EGFR epidermal growth factor receptor [Source:HGNC Symbol;Acc:3236]EGFR epidermal growth factor receptor [Source:HGNC Symbol;Acc:3236]EGFR epidermal growth factor receptor [Source:HGNC Symbol;Acc:3236]EGFR epidermal growth factor receptor [Source:HGNC Symbol;Acc:3236]EGFR epidermal growth factor receptor [Source:HGNC Symbol;Acc:3236]EGFR epidermal growth factor receptor [Source:HGNC Symbol;Acc:3236]EGFR epidermal growth factor receptor [Source:HGNC Symbol;Acc:3236]

EGFR epidermal growth factor receptor [Source:HGNC Symbol;Acc:3236]EGFR epidermal growth factor receptor [Source:HGNC Symbol;Acc:3236]EGFR epidermal growth factor receptor [Source:HGNC Symbol;Acc:3236]EGFR epidermal growth factor receptor [Source:HGNC Symbol;Acc:3236]EGFR epidermal growth factor receptor [Source:HGNC Symbol;Acc:3236]EGFR epidermal growth factor receptor [Source:HGNC Symbol;Acc:3236]EGFR epidermal growth factor receptor [Source:HGNC Symbol;Acc:3236]EGFR epidermal growth factor receptor [Source:HGNC Symbol;Acc:3236]EGFR epidermal growth factor receptor [Source:HGNC Symbol;Acc:3236]EGFR epidermal growth factor receptor [Source:HGNC Symbol;Acc:3236]EGFR epidermal growth factor receptor [Source:HGNC Symbol;Acc:3236]EGFR epidermal growth factor receptor [Source:HGNC Symbol;Acc:3236]EGFR epidermal growth factor receptor [Source:HGNC Symbol;Acc:3236]EGFR epidermal growth factor receptor [Source:HGNC Symbol;Acc:3236]EGFR epidermal growth factor receptor [Source:HGNC Symbol;Acc:3236]EGFR epidermal growth factor receptor [Source:HGNC Symbol;Acc:3236]EGFR epidermal growth factor receptor [Source:HGNC Symbol;Acc:3236]EGFR epidermal growth factor receptor [Source:HGNC Symbol;Acc:3236]EGFR epidermal growth factor receptor [Source:HGNC Symbol;Acc:3236]EGFR epidermal growth factor receptor [Source:HGNC Symbol;Acc:3236]EGFR epidermal growth factor receptor [Source:HGNC Symbol;Acc:3236]EGFR epidermal growth factor receptor [Source:HGNC Symbol;Acc:3236]ENTPD1 ENTH domain containing 1 [Source:HGNC Symbol;Acc:26352]ENTPD1 ENTH domain containing 1 [Source:HGNC Symbol;Acc:26352]ENTPD1 ENTH domain containing 1 [Source:HGNC Symbol;Acc:26352]ENTPD1 ENTH domain containing 1 [Source:HGNC Symbol;Acc:26352]ENTPD1 ENTH domain containing 1 [Source:HGNC Symbol;Acc:26352]ENTPD1 ENTH domain containing 1 [Source:HGNC Symbol;Acc:26352]ENTPD1 ENTH domain containing 1 [Source:HGNC Symbol;Acc:26352]ENTPD1 ENTH domain containing 1 [Source:HGNC Symbol;Acc:26352]ENTPD1 ENTH domain containing 1 [Source:HGNC Symbol;Acc:26352]ENTPD1 ENTH domain containing 1 [Source:HGNC Symbol;Acc:26352]ENTPD1 ENTH domain containing 1 [Source:HGNC Symbol;Acc:26352]ENTPD1 ENTH domain containing 1 [Source:HGNC Symbol;Acc:26352]ENTPD1 ENTH domain containing 1 [Source:HGNC Symbol;Acc:26352]ENTPD1 ENTH domain containing 1 [Source:HGNC Symbol;Acc:26352]ENTPD1 ENTH domain containing 1 [Source:HGNC Symbol;Acc:26352]FADS1 fatty acid desaturase 1 [Source:HGNC Symbol;Acc:3574]FADS1 fatty acid desaturase 1 [Source:HGNC Symbol;Acc:3574]FADS1 fatty acid desaturase 1 [Source:HGNC Symbol;Acc:3574]FADS1 fatty acid desaturase 1 [Source:HGNC Symbol;Acc:3574]FADS1 fatty acid desaturase 1 [Source:HGNC Symbol;Acc:3574]FADS1 fatty acid desaturase 1 [Source:HGNC Symbol;Acc:3574]FADS1 fatty acid desaturase 1 [Source:HGNC Symbol;Acc:3574]FADS1 fatty acid desaturase 1 [Source:HGNC Symbol;Acc:3574]FADS1 fatty acid desaturase 1 [Source:HGNC Symbol;Acc:3574]

FADS1 fatty acid desaturase 1 [Source:HGNC Symbol;Acc:3574]FADS1 fatty acid desaturase 1 [Source:HGNC Symbol;Acc:3574]FADS1 fatty acid desaturase 1 [Source:HGNC Symbol;Acc:3574]FADS1 fatty acid desaturase 1 [Source:HGNC Symbol;Acc:3574]FADS1 fatty acid desaturase 1 [Source:HGNC Symbol;Acc:3574]FADS1 fatty acid desaturase 1 [Source:HGNC Symbol;Acc:3574]FADS1 fatty acid desaturase 1 [Source:HGNC Symbol;Acc:3574]FADS1 fatty acid desaturase 1 [Source:HGNC Symbol;Acc:3574]FADS1 fatty acid desaturase 1 [Source:HGNC Symbol;Acc:3574]FADS1 fatty acid desaturase 1 [Source:HGNC Symbol;Acc:3574]FADS1 fatty acid desaturase 1 [Source:HGNC Symbol;Acc:3574]FADS1 fatty acid desaturase 1 [Source:HGNC Symbol;Acc:3574]FADS1 fatty acid desaturase 1 [Source:HGNC Symbol;Acc:3574]FADS1 fatty acid desaturase 1 [Source:HGNC Symbol;Acc:3574]FADS1 fatty acid desaturase 1 [Source:HGNC Symbol;Acc:3574]FADS1 fatty acid desaturase 1 [Source:HGNC Symbol;Acc:3574]GPHN gephyrin [Source:HGNC Symbol;Acc:15465]GPHN gephyrin [Source:HGNC Symbol;Acc:15465]GPHN gephyrin [Source:HGNC Symbol;Acc:15465]GPHN gephyrin [Source:HGNC Symbol;Acc:15465]GPHN gephyrin [Source:HGNC Symbol;Acc:15465]GPHN gephyrin [Source:HGNC Symbol;Acc:15465]GPHN gephyrin [Source:HGNC Symbol;Acc:15465]GPHN gephyrin [Source:HGNC Symbol;Acc:15465]GPHN gephyrin [Source:HGNC Symbol;Acc:15465]GPHN gephyrin [Source:HGNC Symbol;Acc:15465]GPHN gephyrin [Source:HGNC Symbol;Acc:15465]GPHN gephyrin [Source:HGNC Symbol;Acc:15465]GPHN gephyrin [Source:HGNC Symbol;Acc:15465]GSS glutathione synthetase [Source:HGNC Symbol;Acc:4624]GSS glutathione synthetase [Source:HGNC Symbol;Acc:4624]GSS glutathione synthetase [Source:HGNC Symbol;Acc:4624]GSS glutathione synthetase [Source:HGNC Symbol;Acc:4624]GSS glutathione synthetase [Source:HGNC Symbol;Acc:4624]GSS glutathione synthetase [Source:HGNC Symbol;Acc:4624]GSS glutathione synthetase [Source:HGNC Symbol;Acc:4624]GSS glutathione synthetase [Source:HGNC Symbol;Acc:4624]GSS glutathione synthetase [Source:HGNC Symbol;Acc:4624]GSS glutathione synthetase [Source:HGNC Symbol;Acc:4624]GSS glutathione synthetase [Source:HGNC Symbol;Acc:4624]GSS glutathione synthetase [Source:HGNC Symbol;Acc:4624]HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydrataseHADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional proteHADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional proteHADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional proteHADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional prote

HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional proteHADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional proteHADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional proteHADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional proteHADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional proteHADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional proteHADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit [Source:HGNC Symbol;Acc:4801]HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit [Source:HGNC Symbol;Acc:4801]HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit [Source:HGNC Symbol;Acc:4801]HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit [Source:HGNC Symbol;Acc:4801]HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit [Source:HGNC Symbol;Acc:4801]HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit [Source:HGNC Symbol;Acc:4801]HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit [Source:HGNC Symbol;Acc:4801]HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit [Source:HGNC Symbol;Acc:4801]HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit [Source:HGNC Symbol;Acc:4801]HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit [Source:HGNC Symbol;Acc:4801]HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit [Source:HGNC Symbol;Acc:4801]HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit [Source:HGNC Symbol;Acc:4801]HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit [Source:HGNC Symbol;Acc:4801]HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit [Source:HGNC Symbol;Acc:4801]HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit [Source:HGNC Symbol;Acc:4801]HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit [Source:HGNC Symbol;Acc:4801]HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit [Source:HGNC Symbol;Acc:4801]HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit [Source:HGNC Symbol;Acc:4801]HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit [Source:HGNC Symbol;Acc:4801]HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit [Source:HGNC Symbol;Acc:4801]HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase [Source:HGNC Symbol;Acc:5006]HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase [Source:HGNC Symbol;Acc:5006]HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase [Source:HGNC Symbol;Acc:5006]HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase [Source:HGNC Symbol;Acc:5006]HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase [Source:HGNC Symbol;Acc:5006]HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase [Source:HGNC Symbol;Acc:5006]HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase [Source:HGNC Symbol;Acc:5006]HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase [Source:HGNC Symbol;Acc:5006]HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase [Source:HGNC Symbol;Acc:5006]HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase [Source:HGNC Symbol;Acc:5006]HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase [Source:HGNC Symbol;Acc:5006]HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase [Source:HGNC Symbol;Acc:5006]HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase [Source:HGNC Symbol;Acc:5006]HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase [Source:HGNC Symbol;Acc:5006]HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase [Source:HGNC Symbol;Acc:5006]HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase [Source:HGNC Symbol;Acc:5006]HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase [Source:HGNC Symbol;Acc:5006]HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase [Source:HGNC Symbol;Acc:5006]HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase [Source:HGNC Symbol;Acc:5006]HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase [Source:HGNC Symbol;Acc:5006]

HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase [Source:HGNC Symbol;Acc:5006]HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase [Source:HGNC Symbol;Acc:5006]HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase [Source:HGNC Symbol;Acc:5006]HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase [Source:HGNC Symbol;Acc:5006]HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase [Source:HGNC Symbol;Acc:5006]HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase [Source:HGNC Symbol;Acc:5006]INPPL1 inositol polyphosphate phosphatase-like 1 [Source:HGNC Symbol;Acc:6080]INPPL1 inositol polyphosphate phosphatase-like 1 [Source:HGNC Symbol;Acc:6080]INPPL1 inositol polyphosphate phosphatase-like 1 [Source:HGNC Symbol;Acc:6080]INPPL1 inositol polyphosphate phosphatase-like 1 [Source:HGNC Symbol;Acc:6080]INPPL1 inositol polyphosphate phosphatase-like 1 [Source:HGNC Symbol;Acc:6080]INPPL1 inositol polyphosphate phosphatase-like 1 [Source:HGNC Symbol;Acc:6080]INPPL1 inositol polyphosphate phosphatase-like 1 [Source:HGNC Symbol;Acc:6080]INPPL1 inositol polyphosphate phosphatase-like 1 [Source:HGNC Symbol;Acc:6080]INPPL1 inositol polyphosphate phosphatase-like 1 [Source:HGNC Symbol;Acc:6080]INPPL1 inositol polyphosphate phosphatase-like 1 [Source:HGNC Symbol;Acc:6080]INPPL1 inositol polyphosphate phosphatase-like 1 [Source:HGNC Symbol;Acc:6080]INPPL1 inositol polyphosphate phosphatase-like 1 [Source:HGNC Symbol;Acc:6080]INPPL1 inositol polyphosphate phosphatase-like 1 [Source:HGNC Symbol;Acc:6080]INPPL1 inositol polyphosphate phosphatase-like 1 [Source:HGNC Symbol;Acc:6080]INPPL1 inositol polyphosphate phosphatase-like 1 [Source:HGNC Symbol;Acc:6080]INPPL1 inositol polyphosphate phosphatase-like 1 [Source:HGNC Symbol;Acc:6080]INPPL1 inositol polyphosphate phosphatase-like 1 [Source:HGNC Symbol;Acc:6080]INPPL1 inositol polyphosphate phosphatase-like 1 [Source:HGNC Symbol;Acc:6080]INPPL1 inositol polyphosphate phosphatase-like 1 [Source:HGNC Symbol;Acc:6080]INPPL1 inositol polyphosphate phosphatase-like 1 [Source:HGNC Symbol;Acc:6080]INPPL1 inositol polyphosphate phosphatase-like 1 [Source:HGNC Symbol;Acc:6080]INPPL1 inositol polyphosphate phosphatase-like 1 [Source:HGNC Symbol;Acc:6080]INPPL1 inositol polyphosphate phosphatase-like 1 [Source:HGNC Symbol;Acc:6080]INPPL1 inositol polyphosphate phosphatase-like 1 [Source:HGNC Symbol;Acc:6080]INPPL1 inositol polyphosphate phosphatase-like 1 [Source:HGNC Symbol;Acc:6080]INPPL1 inositol polyphosphate phosphatase-like 1 [Source:HGNC Symbol;Acc:6080]INPPL1 inositol polyphosphate phosphatase-like 1 [Source:HGNC Symbol;Acc:6080]INPPL1 inositol polyphosphate phosphatase-like 1 [Source:HGNC Symbol;Acc:6080]INPPL1 inositol polyphosphate phosphatase-like 1 [Source:HGNC Symbol;Acc:6080]KCNC1 potassium voltage-gated channel, Shaw-related subfamily, member 1 [SourKCNC1 potassium voltage-gated channel, Shaw-related subfamily, member 1 [Source:HGNC Symbol;Acc:62KCNC1 potassium voltage-gated channel, Shaw-related subfamily, member 1 [Source:HGNC Symbol;Acc:62KCNC1 potassium voltage-gated channel, Shaw-related subfamily, member 1 [Source:HGNC Symbol;Acc:62KCNC1 potassium voltage-gated channel, Shaw-related subfamily, member 1 [Source:HGNC Symbol;Acc:62LDHA lactate dehydrogenase A [Source:HGNC Symbol;Acc:6535]LDHA lactate dehydrogenase A [Source:HGNC Symbol;Acc:6535]LDHA lactate dehydrogenase A [Source:HGNC Symbol;Acc:6535]LDHA lactate dehydrogenase A [Source:HGNC Symbol;Acc:6535]LDHA lactate dehydrogenase A [Source:HGNC Symbol;Acc:6535]LDHA lactate dehydrogenase A [Source:HGNC Symbol;Acc:6535]

LDHA lactate dehydrogenase A [Source:HGNC Symbol;Acc:6535]LDHA lactate dehydrogenase A [Source:HGNC Symbol;Acc:6535]LDHA lactate dehydrogenase A [Source:HGNC Symbol;Acc:6535]LDHA lactate dehydrogenase A [Source:HGNC Symbol;Acc:6535]LDHA lactate dehydrogenase A [Source:HGNC Symbol;Acc:6535]LDHA lactate dehydrogenase A [Source:HGNC Symbol;Acc:6535]MTOR mechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC SyMTOR mechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942]MTOR mechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942]MTOR mechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942]MTOR mechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942]MTOR mechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942]MTOR mechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942]MTOR mechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942]MTOR mechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942]MTOR mechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942]MTOR mechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942]MTOR mechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942]MTOR mechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942]MTOR mechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942]MTOR mechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942]MTOR mechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942]MTOR mechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942]MTOR mechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942]MTOR mechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942]MTOR mechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942]MTOR mechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942]MTOR mechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942]MTOR mechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942]MTOR mechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942]MTOR mechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942]MTOR mechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942]MTOR mechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942]MTOR mechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942]MTOR mechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942]MTOR mechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942]MTOR mechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942]MTOR mechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942]MTOR mechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942]MTOR mechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942]MTOR mechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942]MTOR mechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942]MTOR mechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942]MTOR mechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942]MTOR mechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942]MTOR mechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942]

MTOR mechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942]MTOR mechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942]MTOR mechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942]MTOR mechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942]MTOR mechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942]MTOR mechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942]MTOR mechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942]MTOR mechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942]MTOR mechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942]MTOR mechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942]NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) [Source:NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) [Source:NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) [Source:NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) [Source:NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) [Source:NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) [Source:NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) [Source:NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) [Source:NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) [Source:NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) [Source:HGNC Symbol;Acc:7707]NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) [Source:HGNC Symbol;Acc:7707]NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) [Source:HGNC Symbol;Acc:7707]NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) [Source:HGNC Symbol;Acc:7707]NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) [Source:HGNC Symbol;Acc:7707]NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) [Source:HGNC Symbol;Acc:7707]NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) [Source:HGNC Symbol;Acc:7707]NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) [Source:HGNC Symbol;Acc:7707]NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) [Source:HGNC Symbol;Acc:7707]NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa [Source:HGNC SymNDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa [Source:HGNC Symbol;Acc:7716]NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa [Source:HGNC Symbol;Acc:7716]NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa [Source:HGNC Symbol;Acc:7716]NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa [Source:HGNC Symbol;Acc:7716]NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa [Source:HGNC Symbol;Acc:7716]NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa [Source:HGNC Symbol;Acc:7716]NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa [Source:HGNC Symbol;Acc:7716]NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa [Source:HGNC Symbol;Acc:7716]NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa [Source:HGNC Symbol;Acc:7716]NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa [Source:HGNC Symbol;Acc:7716]NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa [Source:HGNC Symbol;Acc:7716]NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa [Source:HGNC Symbol;Acc:7716]NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa [Source:HGNC Symbol;Acc:7716]NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa [Source:HGNC Symbol;Acc:7716]NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa [Source:HGNC Symbol;Acc:7716]NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa [Source:HGNC Symbol;Acc:7716]

NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa [Source:HGNC Symbol;Acc:7716]NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) [Source:HGNC Symbol;ANR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) [Source:HGNC Symbol;ANR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) [Source:HGNC Symbol;ANR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) [Source:HGNC Symbol;ANR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) [Source:HGNC Symbol;ANR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) [Source:HGNC Symbol;ANR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) [Source:HGNC Symbol;ANR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) [Source:HGNC Symbol;ANR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) [Source:HGNC Symbol;ANR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) [Source:HGNC Symbol;ANR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) [Source:HGNC Symbol;ANR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) [Source:HGNC Symbol;ANR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) [Source:HGNC Symbol;ANR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) [Source:HGNC Symbol;ANR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) [Source:HGNC Symbol;ANUP98 nucleoporin 98kDa [Source:HGNC Symbol;Acc:8068]NUP98 nucleoporin 98kDa [Source:HGNC Symbol;Acc:8068]NUP98 nucleoporin 98kDa [Source:HGNC Symbol;Acc:8068]NUP98 nucleoporin 98kDa [Source:HGNC Symbol;Acc:8068]NUP98 nucleoporin 98kDa [Source:HGNC Symbol;Acc:8068]NUP98 nucleoporin 98kDa [Source:HGNC Symbol;Acc:8068]NUP98 nucleoporin 98kDa [Source:HGNC Symbol;Acc:8068]NUP98 nucleoporin 98kDa [Source:HGNC Symbol;Acc:8068]NUP98 nucleoporin 98kDa [Source:HGNC Symbol;Acc:8068]NUP98 nucleoporin 98kDa [Source:HGNC Symbol;Acc:8068]NUP98 nucleoporin 98kDa [Source:HGNC Symbol;Acc:8068]NUP98 nucleoporin 98kDa [Source:HGNC Symbol;Acc:8068]NUP98 nucleoporin 98kDa [Source:HGNC Symbol;Acc:8068]NUP98 nucleoporin 98kDa [Source:HGNC Symbol;Acc:8068]NUP98 nucleoporin 98kDa [Source:HGNC Symbol;Acc:8068]NUP98 nucleoporin 98kDa [Source:HGNC Symbol;Acc:8068]NUP98 nucleoporin 98kDa [Source:HGNC Symbol;Acc:8068]NUP98 nucleoporin 98kDa [Source:HGNC Symbol;Acc:8068]NUP98 nucleoporin 98kDa [Source:HGNC Symbol;Acc:8068]NUP98 nucleoporin 98kDa [Source:HGNC Symbol;Acc:8068]NUP98 nucleoporin 98kDa [Source:HGNC Symbol;Acc:8068]NUP98 nucleoporin 98kDa [Source:HGNC Symbol;Acc:8068]NUP98 nucleoporin 98kDa [Source:HGNC Symbol;Acc:8068]NUP98 nucleoporin 98kDa [Source:HGNC Symbol;Acc:8068]NUP98 nucleoporin 98kDa [Source:HGNC Symbol;Acc:8068]NUP98 nucleoporin 98kDa [Source:HGNC Symbol;Acc:8068]NUP98 nucleoporin 98kDa [Source:HGNC Symbol;Acc:8068]NUP98 nucleoporin 98kDa [Source:HGNC Symbol;Acc:8068]NUP98 nucleoporin 98kDa [Source:HGNC Symbol;Acc:8068]

NUP98 nucleoporin 98kDa [Source:HGNC Symbol;Acc:8068]NUP98 nucleoporin 98kDa [Source:HGNC Symbol;Acc:8068]NUP98 nucleoporin 98kDa [Source:HGNC Symbol;Acc:8068]NUP98 nucleoporin 98kDa [Source:HGNC Symbol;Acc:8068]NUP98 nucleoporin 98kDa [Source:HGNC Symbol;Acc:8068]NUP98 nucleoporin 98kDa [Source:HGNC Symbol;Acc:8068]NUP98 nucleoporin 98kDa [Source:HGNC Symbol;Acc:8068]NUP98 nucleoporin 98kDa [Source:HGNC Symbol;Acc:8068]NUP98 nucleoporin 98kDa [Source:HGNC Symbol;Acc:8068]NUP98 nucleoporin 98kDa [Source:HGNC Symbol;Acc:8068]NUP98 nucleoporin 98kDa [Source:HGNC Symbol;Acc:8068]NUP98 nucleoporin 98kDa [Source:HGNC Symbol;Acc:8068]NUP98 nucleoporin 98kDa [Source:HGNC Symbol;Acc:8068]NUP98 nucleoporin 98kDa [Source:HGNC Symbol;Acc:8068]NUP98 nucleoporin 98kDa [Source:HGNC Symbol;Acc:8068]NUP98 nucleoporin 98kDa [Source:HGNC Symbol;Acc:8068]NUP98 nucleoporin 98kDa [Source:HGNC Symbol;Acc:8068]PAH phenylalanine hydroxylase [Source:HGNC Symbol;Acc:8582]PAH phenylalanine hydroxylase [Source:HGNC Symbol;Acc:8582]PAH phenylalanine hydroxylase [Source:HGNC Symbol;Acc:8582]PAH phenylalanine hydroxylase [Source:HGNC Symbol;Acc:8582]PAH phenylalanine hydroxylase [Source:HGNC Symbol;Acc:8582]PAH phenylalanine hydroxylase [Source:HGNC Symbol;Acc:8582]PAH phenylalanine hydroxylase [Source:HGNC Symbol;Acc:8582]PAH phenylalanine hydroxylase [Source:HGNC Symbol;Acc:8582]PAH phenylalanine hydroxylase [Source:HGNC Symbol;Acc:8582]PAH phenylalanine hydroxylase [Source:HGNC Symbol;Acc:8582]PAH phenylalanine hydroxylase [Source:HGNC Symbol;Acc:8582]PFKM phosphofructokinase, muscle [Source:HGNC Symbol;Acc:8877]PFKM phosphofructokinase, muscle [Source:HGNC Symbol;Acc:8877]PFKM phosphofructokinase, muscle [Source:HGNC Symbol;Acc:8877]PFKM phosphofructokinase, muscle [Source:HGNC Symbol;Acc:8877]PFKM phosphofructokinase, muscle [Source:HGNC Symbol;Acc:8877]PFKM phosphofructokinase, muscle [Source:HGNC Symbol;Acc:8877]PFKM phosphofructokinase, muscle [Source:HGNC Symbol;Acc:8877]PFKM phosphofructokinase, muscle [Source:HGNC Symbol;Acc:8877]PFKM phosphofructokinase, muscle [Source:HGNC Symbol;Acc:8877]PFKM phosphofructokinase, muscle [Source:HGNC Symbol;Acc:8877]PFKM phosphofructokinase, muscle [Source:HGNC Symbol;Acc:8877]PFKM phosphofructokinase, muscle [Source:HGNC Symbol;Acc:8877]PFKM phosphofructokinase, muscle [Source:HGNC Symbol;Acc:8877]PFKM phosphofructokinase, muscle [Source:HGNC Symbol;Acc:8877]PFKM phosphofructokinase, muscle [Source:HGNC Symbol;Acc:8877]PFKM phosphofructokinase, muscle [Source:HGNC Symbol;Acc:8877]PFKM phosphofructokinase, muscle [Source:HGNC Symbol;Acc:8877]PFKM phosphofructokinase, muscle [Source:HGNC Symbol;Acc:8877]

PFKM phosphofructokinase, muscle [Source:HGNC Symbol;Acc:8877]PGM1 phosphoglucomutase 1 [Source:HGNC Symbol;Acc:8905]PGM1 phosphoglucomutase 1 [Source:HGNC Symbol;Acc:8905]PGM1 phosphoglucomutase 1 [Source:HGNC Symbol;Acc:8905]PGM1 phosphoglucomutase 1 [Source:HGNC Symbol;Acc:8905]PGM1 phosphoglucomutase 1 [Source:HGNC Symbol;Acc:8905]PGM1 phosphoglucomutase 1 [Source:HGNC Symbol;Acc:8905]PGM1 phosphoglucomutase 1 [Source:HGNC Symbol;Acc:8905]PGM1 phosphoglucomutase 1 [Source:HGNC Symbol;Acc:8905]PGM1 phosphoglucomutase 1 [Source:HGNC Symbol;Acc:8905]PGM1 phosphoglucomutase 1 [Source:HGNC Symbol;Acc:8905]PGM1 phosphoglucomutase 1 [Source:HGNC Symbol;Acc:8905]PGM1 phosphoglucomutase 1 [Source:HGNC Symbol;Acc:8905]PGM1 phosphoglucomutase 1 [Source:HGNC Symbol;Acc:8905]PGM1 phosphoglucomutase 1 [Source:HGNC Symbol;Acc:8905]PGM1 phosphoglucomutase 1 [Source:HGNC Symbol;Acc:8905]PGM1 phosphoglucomutase 1 [Source:HGNC Symbol;Acc:8905]PGM1 phosphoglucomutase 1 [Source:HGNC Symbol;Acc:8905]PGM1 phosphoglucomutase 1 [Source:HGNC Symbol;Acc:8905]POMT2 protein-O-mannosyltransferase 2 [Source:HGNC Symbol;Acc:19743]POMT2 protein-O-mannosyltransferase 2 [Source:HGNC Symbol;Acc:19743]POMT2 protein-O-mannosyltransferase 2 [Source:HGNC Symbol;Acc:19743]POMT2 protein-O-mannosyltransferase 2 [Source:HGNC Symbol;Acc:19743]POMT2 protein-O-mannosyltransferase 2 [Source:HGNC Symbol;Acc:19743]POMT2 protein-O-mannosyltransferase 2 [Source:HGNC Symbol;Acc:19743]POMT2 protein-O-mannosyltransferase 2 [Source:HGNC Symbol;Acc:19743]POMT2 protein-O-mannosyltransferase 2 [Source:HGNC Symbol;Acc:19743]POMT2 protein-O-mannosyltransferase 2 [Source:HGNC Symbol;Acc:19743]POMT2 protein-O-mannosyltransferase 2 [Source:HGNC Symbol;Acc:19743]POMT2 protein-O-mannosyltransferase 2 [Source:HGNC Symbol;Acc:19743]POMT2 protein-O-mannosyltransferase 2 [Source:HGNC Symbol;Acc:19743]POMT2 protein-O-mannosyltransferase 2 [Source:HGNC Symbol;Acc:19743]POMT2 protein-O-mannosyltransferase 2 [Source:HGNC Symbol;Acc:19743]POMT2 protein-O-mannosyltransferase 2 [Source:HGNC Symbol;Acc:19743]POMT2 protein-O-mannosyltransferase 2 [Source:HGNC Symbol;Acc:19743]POMT2 protein-O-mannosyltransferase 2 [Source:HGNC Symbol;Acc:19743]POMT2 protein-O-mannosyltransferase 2 [Source:HGNC Symbol;Acc:19743]POMT2 protein-O-mannosyltransferase 2 [Source:HGNC Symbol;Acc:19743]POMT2 protein-O-mannosyltransferase 2 [Source:HGNC Symbol;Acc:19743]POMT2 protein-O-mannosyltransferase 2 [Source:HGNC Symbol;Acc:19743]PPIB peptidylprolyl isomerase B (cyclophilin B) [Source:HGNC Symbol;Acc:9255]PPIB peptidylprolyl isomerase B (cyclophilin B) [Source:HGNC Symbol;Acc:9255]PPIB peptidylprolyl isomerase B (cyclophilin B) [Source:HGNC Symbol;Acc:9255]PPIB peptidylprolyl isomerase B (cyclophilin B) [Source:HGNC Symbol;Acc:9255]PPIB peptidylprolyl isomerase B (cyclophilin B) [Source:HGNC Symbol;Acc:9255]PPIB peptidylprolyl isomerase B (cyclophilin B) [Source:HGNC Symbol;Acc:9255]

PPIB peptidylprolyl isomerase B (cyclophilin B) [Source:HGNC Symbol;Acc:9255]PPIB peptidylprolyl isomerase B (cyclophilin B) [Source:HGNC Symbol;Acc:9255]PPIB peptidylprolyl isomerase B (cyclophilin B) [Source:HGNC Symbol;Acc:9255]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]

PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]SLC16A1 solute carrier family 16, member 1 (monocarboxylic acid transporter 1) [SSLC16A1 solute carrier family 16, member 1 (monocarboxylic acid transporter 1) [Source:HGNC Symbol;Acc:SLC16A1 solute carrier family 16, member 1 (monocarboxylic acid transporter 1) [Source:HGNC Symbol;Acc:SLC16A1 solute carrier family 16, member 1 (monocarboxylic acid transporter 1) [Source:HGNC Symbol;Acc:SLC16A1 solute carrier family 16, member 1 (monocarboxylic acid transporter 1) [Source:HGNC Symbol;Acc:SLC16A1 solute carrier family 16, member 1 (monocarboxylic acid transporter 1) [Source:HGNC Symbol;Acc:

SLC16A1 solute carrier family 16, member 1 (monocarboxylic acid transporter 1) [Source:HGNC Symbol;Acc:SLC16A1 solute carrier family 16, member 1 (monocarboxylic acid transporter 1) [Source:HGNC Symbol;Acc:SLC25A12 solute carrier family 25 (aspartate/glutamate carrier), member 12 [SourceSLC25A12 solute carrier family 25 (aspartate/glutamate carrier), member 12 [Source:HGNC Symbol;Acc:10982SLC25A12 solute carrier family 25 (aspartate/glutamate carrier), member 12 [Source:HGNC Symbol;Acc:10982SLC25A12 solute carrier family 25 (aspartate/glutamate carrier), member 12 [Source:HGNC Symbol;Acc:10982SLC25A12 solute carrier family 25 (aspartate/glutamate carrier), member 12 [Source:HGNC Symbol;Acc:10982SLC25A12 solute carrier family 25 (aspartate/glutamate carrier), member 12 [Source:HGNC Symbol;Acc:10982SLC25A12 solute carrier family 25 (aspartate/glutamate carrier), member 12 [Source:HGNC Symbol;Acc:10982SLC25A12 solute carrier family 25 (aspartate/glutamate carrier), member 12 [Source:HGNC Symbol;Acc:10982SLC25A12 solute carrier family 25 (aspartate/glutamate carrier), member 12 [Source:HGNC Symbol;Acc:10982SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 [SourceSLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 [Source:HGNC Symbol;Acc:10983SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 [Source:HGNC Symbol;Acc:10983SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 [Source:HGNC Symbol;Acc:10983SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 [Source:HGNC Symbol;Acc:10983SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 [Source:HGNC Symbol;Acc:10983SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 [Source:HGNC Symbol;Acc:10983SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 [Source:HGNC Symbol;Acc:10983SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 [Source:HGNC Symbol;Acc:10983SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 [Source:HGNC Symbol;Acc:10983SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 [Source:HGNC Symbol;Acc:10983]SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 [Source:HGNC Symbol;Acc:10983]SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 [Source:HGNC Symbol;Acc:10983]SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 [Source:HGNC Symbol;Acc:10983]SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), membeSLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 [Source:HGNC SymboSLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 [Source:HGNC Symbol;Acc:10989]SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 [Source:HGNC Symbol;Acc:10989]SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 [Source:HGNC Symbol;Acc:10989]SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 [Source:HGNC Symbol;Acc:10989]SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 [Source:HGNC Symbol;Acc:10989]SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 [Source:HGNC Symbol;Acc:10989]SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 [Source:HGNC Symbol;Acc:10989]SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 [Source:HGNC Symbol;Acc:10989]SNCA synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC SSNCA synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138]SNCA synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138]SNCA synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138]SNCA synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138]SNCA synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138]SNCA synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138]SNCA synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138]SNCA synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138]SNCA synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138]SNCA synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138]

SNCA synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138]SNCA synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138]SNCA synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138]SNCA synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138]SNCA synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138]SNCA synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138]SNCA synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138]SNCA synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138]SNCA synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138]SNCA synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138]SNCA synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138]SNCA synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138]SNCA synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138]SNCA synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138]SNCA synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138]SNCA synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138]SNCA synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138]SNCA synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138]SNCA synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138]SNCA synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138]SNCA synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138]SNCA synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138]SNCA synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138]SNCA synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138]SNCA synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138]SNCA synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138]SNCA synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138]SNCA synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138]SNCA synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138]SNCA synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138]SNCA synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138]SNCA synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138]SNCA synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138]SNCA synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138]SNCA synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138]SNCA synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138]SNCA synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138]SNCA synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138]SNCA synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138]SNCA synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138]SNCA synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138]SNCA synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138]SNCA synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138]SNCA synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138]SNCA synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138]SNCA synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138]

SNCA synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138]SNCA synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138]SNCA synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138]SNCA synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138]SNCA synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138]SNCA synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138]SNCA synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138]SNCA synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138]SNCA synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138]SNCA synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138]SNCA synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138]SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) [Source:HSPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) [Source:HGNC Symbol;Acc:11237]SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) [Source:HGNC Symbol;Acc:11237]SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) [Source:HGNC Symbol;Acc:11237]SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) [Source:HGNC Symbol;Acc:11237]SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) [Source:HGNC Symbol;Acc:11237]SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) [Source:HGNC Symbol;Acc:11237]SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) [Source:HGNC Symbol;Acc:11237]SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) [Source:HGNC Symbol;Acc:11237]SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) [Source:HGNC Symbol;Acc:11237]SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) [Source:HGNC Symbol;Acc:11237]SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) [Source:HGNC Symbol;Acc:11237]SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) [Source:HGNC Symbol;Acc:11237]SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) [Source:HGNC Symbol;Acc:11237]SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) [Source:HGNC Symbol;Acc:11237]SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) [Source:HGNC Symbol;Acc:11237]SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) [Source:HGNC Symbol;Acc:11237]SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) [Source:HGNC Symbol;Acc:11237]SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) [Source:HGNC Symbol;Acc:11237]SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) [Source:HGNC Symbol;Acc:11237]SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) [Source:HGNC Symbol;Acc:11237]SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) [Source:HGNC Symbol;Acc:11237]SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) [Source:HGNC Symbol;Acc:11237]SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) [Source:HGNC Symbol;Acc:11237]SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) [Source:HGNC Symbol;Acc:11237]SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) [Source:HGNC Symbol;Acc:11237]SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) [Source:HGNC Symbol;Acc:11237]SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) [Source:HGNC Symbol;Acc:11237]SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) [Source:HGNC Symbol;Acc:11237]SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) [Source:HGNC Symbol;Acc:11237]SUCLA2 succinate-CoA ligase, ADP-forming, beta subunit [Source:HGNC Symbol;Acc:SUCLA2 succinate-CoA ligase, ADP-forming, beta subunit [Source:HGNC Symbol;Acc:11448]SUCLA2 succinate-CoA ligase, ADP-forming, beta subunit [Source:HGNC Symbol;Acc:11448]SUCLA2 succinate-CoA ligase, ADP-forming, beta subunit [Source:HGNC Symbol;Acc:11448]SUCLA2 succinate-CoA ligase, ADP-forming, beta subunit [Source:HGNC Symbol;Acc:11448]

SUCLA2 succinate-CoA ligase, ADP-forming, beta subunit [Source:HGNC Symbol;Acc:11448]SUCLA2 succinate-CoA ligase, ADP-forming, beta subunit [Source:HGNC Symbol;Acc:11448]SUCLA2 succinate-CoA ligase, ADP-forming, beta subunit [Source:HGNC Symbol;Acc:11448]SUCLA2 succinate-CoA ligase, ADP-forming, beta subunit [Source:HGNC Symbol;Acc:11448]SUCLA2 succinate-CoA ligase, ADP-forming, beta subunit [Source:HGNC Symbol;Acc:11448]SYP synaptophysin [Source:HGNC Symbol;Acc:11506]SYP synaptophysin [Source:HGNC Symbol;Acc:11506]SYP synaptophysin [Source:HGNC Symbol;Acc:11506]SYP synaptophysin [Source:HGNC Symbol;Acc:11506]SYP synaptophysin [Source:HGNC Symbol;Acc:11506]SYP synaptophysin [Source:HGNC Symbol;Acc:11506]SYP synaptophysin [Source:HGNC Symbol;Acc:11506]TMPRSS5 transmembrane protease, serine 5 [Source:HGNC Symbol;Acc:14908]TMPRSS5 transmembrane protease, serine 5 [Source:HGNC Symbol;Acc:14908]TMPRSS5 transmembrane protease, serine 5 [Source:HGNC Symbol;Acc:14908]TMPRSS5 transmembrane protease, serine 5 [Source:HGNC Symbol;Acc:14908]TMPRSS5 transmembrane protease, serine 5 [Source:HGNC Symbol;Acc:14908]TMPRSS5 transmembrane protease, serine 5 [Source:HGNC Symbol;Acc:14908]TMPRSS5 transmembrane protease, serine 5 [Source:HGNC Symbol;Acc:14908]TMPRSS5 transmembrane protease, serine 5 [Source:HGNC Symbol;Acc:14908]TMPRSS5 transmembrane protease, serine 5 [Source:HGNC Symbol;Acc:14908]TMPRSS5 transmembrane protease, serine 5 [Source:HGNC Symbol;Acc:14908]TMPRSS5 transmembrane protease, serine 5 [Source:HGNC Symbol;Acc:14908]TMPRSS5 transmembrane protease, serine 5 [Source:HGNC Symbol;Acc:14908]TMPRSS5 transmembrane protease, serine 5 [Source:HGNC Symbol;Acc:14908]TMPRSS5 transmembrane protease, serine 5 [Source:HGNC Symbol;Acc:14908]TMPRSS5 transmembrane protease, serine 5 [Source:HGNC Symbol;Acc:14908]TMPRSS5 transmembrane protease, serine 5 [Source:HGNC Symbol;Acc:14908]TMPRSS5 transmembrane protease, serine 5 [Source:HGNC Symbol;Acc:14908]TNFRSF8 tumor necrosis factor receptor superfamily, member 8 [Source:HGNC SymboTNFRSF8 tumor necrosis factor receptor superfamily, member 8 [Source:HGNC Symbol;Acc:11923]TNFRSF8 tumor necrosis factor receptor superfamily, member 8 [Source:HGNC Symbol;Acc:11923]TNFRSF8 tumor necrosis factor receptor superfamily, member 8 [Source:HGNC Symbol;Acc:11923]TNFRSF8 tumor necrosis factor receptor superfamily, member 8 [Source:HGNC Symbol;Acc:11923]TNFRSF8 tumor necrosis factor receptor superfamily, member 8 [Source:HGNC Symbol;Acc:11923]TNFRSF8 tumor necrosis factor receptor superfamily, member 8 [Source:HGNC Symbol;Acc:11923]TUBG1 tubulin, gamma 1 [Source:HGNC Symbol;Acc:12417]TUBG1 tubulin, gamma 1 [Source:HGNC Symbol;Acc:12417]TUBG1 tubulin, gamma 1 [Source:HGNC Symbol;Acc:12417]TUBG1 tubulin, gamma 1 [Source:HGNC Symbol;Acc:12417]TUBG1 tubulin, gamma 1 [Source:HGNC Symbol;Acc:12417]TUBG1 tubulin, gamma 1 [Source:HGNC Symbol;Acc:12417]TUBG1 tubulin, gamma 1 [Source:HGNC Symbol;Acc:12417]TUBG1 tubulin, gamma 1 [Source:HGNC Symbol;Acc:12417]TYK2 tyrosine kinase 2 [Source:HGNC Symbol;Acc:12440]TYK2 tyrosine kinase 2 [Source:HGNC Symbol;Acc:12440]

TYK2 tyrosine kinase 2 [Source:HGNC Symbol;Acc:12440]TYK2 tyrosine kinase 2 [Source:HGNC Symbol;Acc:12440]TYK2 tyrosine kinase 2 [Source:HGNC Symbol;Acc:12440]TYK2 tyrosine kinase 2 [Source:HGNC Symbol;Acc:12440]TYK2 tyrosine kinase 2 [Source:HGNC Symbol;Acc:12440]TYK2 tyrosine kinase 2 [Source:HGNC Symbol;Acc:12440]TYK2 tyrosine kinase 2 [Source:HGNC Symbol;Acc:12440]TYK2 tyrosine kinase 2 [Source:HGNC Symbol;Acc:12440]TYK2 tyrosine kinase 2 [Source:HGNC Symbol;Acc:12440]TYK2 tyrosine kinase 2 [Source:HGNC Symbol;Acc:12440]TYK2 tyrosine kinase 2 [Source:HGNC Symbol;Acc:12440]TYK2 tyrosine kinase 2 [Source:HGNC Symbol;Acc:12440]TYK2 tyrosine kinase 2 [Source:HGNC Symbol;Acc:12440]TYK2 tyrosine kinase 2 [Source:HGNC Symbol;Acc:12440]TYK2 tyrosine kinase 2 [Source:HGNC Symbol;Acc:12440]TYK2 tyrosine kinase 2 [Source:HGNC Symbol;Acc:12440]TYK2 tyrosine kinase 2 [Source:HGNC Symbol;Acc:12440]TYK2 tyrosine kinase 2 [Source:HGNC Symbol;Acc:12440]TYK2 tyrosine kinase 2 [Source:HGNC Symbol;Acc:12440]TYK2 tyrosine kinase 2 [Source:HGNC Symbol;Acc:12440]TYK2 tyrosine kinase 2 [Source:HGNC Symbol;Acc:12440]TYK2 tyrosine kinase 2 [Source:HGNC Symbol;Acc:12440]TYK2 tyrosine kinase 2 [Source:HGNC Symbol;Acc:12440]TYK2 tyrosine kinase 2 [Source:HGNC Symbol;Acc:12440]TYK2 tyrosine kinase 2 [Source:HGNC Symbol;Acc:12440]TYK2 tyrosine kinase 2 [Source:HGNC Symbol;Acc:12440]TYK2 tyrosine kinase 2 [Source:HGNC Symbol;Acc:12440]TYK2 tyrosine kinase 2 [Source:HGNC Symbol;Acc:12440]TYK2 tyrosine kinase 2 [Source:HGNC Symbol;Acc:12440]TYK2 tyrosine kinase 2 [Source:HGNC Symbol;Acc:12440]TYK2 tyrosine kinase 2 [Source:HGNC Symbol;Acc:12440]TYK2 tyrosine kinase 2 [Source:HGNC Symbol;Acc:12440]TYK2 tyrosine kinase 2 [Source:HGNC Symbol;Acc:12440]TYK2 tyrosine kinase 2 [Source:HGNC Symbol;Acc:12440]TYK2 tyrosine kinase 2 [Source:HGNC Symbol;Acc:12440]TYK2 tyrosine kinase 2 [Source:HGNC Symbol;Acc:12440]TYK2 tyrosine kinase 2 [Source:HGNC Symbol;Acc:12440]TYK2 tyrosine kinase 2 [Source:HGNC Symbol;Acc:12440]UQCRC2 ubiquinol-cytochrome c reductase core protein II [Source:HGNC Symbol;AccUQCRC2 ubiquinol-cytochrome c reductase core protein II [Source:HGNC Symbol;Acc:12586]UQCRC2 ubiquinol-cytochrome c reductase core protein II [Source:HGNC Symbol;Acc:12586]UQCRC2 ubiquinol-cytochrome c reductase core protein II [Source:HGNC Symbol;Acc:12586]UQCRC2 ubiquinol-cytochrome c reductase core protein II [Source:HGNC Symbol;Acc:12586]UQCRC2 ubiquinol-cytochrome c reductase core protein II [Source:HGNC Symbol;Acc:12586]UQCRC2 ubiquinol-cytochrome c reductase core protein II [Source:HGNC Symbol;Acc:12586]UQCRC2 ubiquinol-cytochrome c reductase core protein II [Source:HGNC Symbol;Acc:12586]

UQCRC2 ubiquinol-cytochrome c reductase core protein II [Source:HGNC Symbol;Acc:12586]UQCRC2 ubiquinol-cytochrome c reductase core protein II [Source:HGNC Symbol;Acc:12586]UQCRC2 ubiquinol-cytochrome c reductase core protein II [Source:HGNC Symbol;Acc:12586]UQCRC2 ubiquinol-cytochrome c reductase core protein II [Source:HGNC Symbol;Acc:12586]VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) [Source:HGNC SymVAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) [Source:HGNC Symbol;Acc:12643]VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) [Source:HGNC Symbol;Acc:12643]VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) [Source:HGNC Symbol;Acc:12643]VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) [Source:HGNC Symbol;Acc:12643]VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) [Source:HGNC Symbol;Acc:12643]VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) [Source:HGNC Symbol;Acc:12643]VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) [Source:HGNC Symbol;Acc:12643]VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) [Source:HGNC Symbol;Acc:12643]VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) [Source:HGNC Symbol;Acc:12643]VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) [Source:HGNC Symbol;Acc:12643]VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) [Source:HGNC Symbol;Acc:12643]VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) [Source:HGNC Symbol;Acc:12643]VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) [Source:HGNC Symbol;Acc:12643]VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) [Source:HGNC Symbol;Acc:12643]VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) [Source:HGNC Symbol;Acc:12643]VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) [Source:HGNC Symbol;Acc:12643]VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) [Source:HGNC Symbol;Acc:12643]VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) [Source:HGNC Symbol;Acc:12643]WHSC1 Wolf-Hirschhorn syndrome candidate 1 [Source:HGNC Symbol;Acc:12766]WHSC1 Wolf-Hirschhorn syndrome candidate 1 [Source:HGNC Symbol;Acc:12766]WHSC1 Wolf-Hirschhorn syndrome candidate 1 [Source:HGNC Symbol;Acc:12766]WHSC1 Wolf-Hirschhorn syndrome candidate 1 [Source:HGNC Symbol;Acc:12766]WHSC1 Wolf-Hirschhorn syndrome candidate 1 [Source:HGNC Symbol;Acc:12766]WHSC1 Wolf-Hirschhorn syndrome candidate 1 [Source:HGNC Symbol;Acc:12766]WHSC1 Wolf-Hirschhorn syndrome candidate 1 [Source:HGNC Symbol;Acc:12766]WHSC1 Wolf-Hirschhorn syndrome candidate 1 [Source:HGNC Symbol;Acc:12766]WHSC1 Wolf-Hirschhorn syndrome candidate 1 [Source:HGNC Symbol;Acc:12766]WHSC1 Wolf-Hirschhorn syndrome candidate 1 [Source:HGNC Symbol;Acc:12766]WHSC1 Wolf-Hirschhorn syndrome candidate 1 [Source:HGNC Symbol;Acc:12766]WHSC1 Wolf-Hirschhorn syndrome candidate 1 [Source:HGNC Symbol;Acc:12766]WHSC1 Wolf-Hirschhorn syndrome candidate 1 [Source:HGNC Symbol;Acc:12766]WHSC1 Wolf-Hirschhorn syndrome candidate 1 [Source:HGNC Symbol;Acc:12766]WHSC1 Wolf-Hirschhorn syndrome candidate 1 [Source:HGNC Symbol;Acc:12766]WHSC1 Wolf-Hirschhorn syndrome candidate 1 [Source:HGNC Symbol;Acc:12766]WHSC1 Wolf-Hirschhorn syndrome candidate 1 [Source:HGNC Symbol;Acc:12766]WHSC1 Wolf-Hirschhorn syndrome candidate 1 [Source:HGNC Symbol;Acc:12766]WHSC1 Wolf-Hirschhorn syndrome candidate 1 [Source:HGNC Symbol;Acc:12766]WHSC1 Wolf-Hirschhorn syndrome candidate 1 [Source:HGNC Symbol;Acc:12766]WHSC1 Wolf-Hirschhorn syndrome candidate 1 [Source:HGNC Symbol;Acc:12766]WHSC1 Wolf-Hirschhorn syndrome candidate 1 [Source:HGNC Symbol;Acc:12766]WHSC1 Wolf-Hirschhorn syndrome candidate 1 [Source:HGNC Symbol;Acc:12766]

WHSC1 Wolf-Hirschhorn syndrome candidate 1 [Source:HGNC Symbol;Acc:12766]WHSC1 Wolf-Hirschhorn syndrome candidate 1 [Source:HGNC Symbol;Acc:12766]

Supplementary Table S9B: Biological Processes and KEGG pathways connected with HD associated genes without TVS and targets of FDA approved drugs or potential targets o f drugsNo of Go ter (BP) GO ID GO term description

18 GO:0006382 adenosine to inosine editingGO:0006396 RNA processingGO:0006397 mRNA processingGO:0006606 protein import into nucleusGO:0006611 protein export from nucleusGO:0009615 response to virusGO:0010467 gene expressionGO:0016553 base conversion or substitution editingGO:0016556 mRNA modificationGO:0019221 cytokine-mediated signaling pathwayGO:0031047 gene silencing by RNAGO:0035455 response to interferon-alphaGO:0043066 negative regulation of apoptotic processGO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylationGO:0045070 positive regulation of viral genome replicationGO:0045087 innate immune responseGO:0051607 defense response to virusGO:0060337 type I interferon-mediated signaling pathway

16 GO:0002576 platelet degranulationGO:0005975 carbohydrate metabolic processGO:0006000 fructose metabolic processGO:0006006 glucose metabolic processGO:0006094 gluconeogenesisGO:0006096 glycolysisGO:0006754 ATP biosynthetic processGO:0006941 striated muscle contractionGO:0007015 actin filament organizationGO:0007596 blood coagulationGO:0008360 regulation of cell shapeGO:0030168 platelet activationGO:0030388 fructose 1,6-bisphosphate metabolic processGO:0044281 small molecule metabolic processGO:0046716 muscle cell homeostasisGO:0051289 protein homotetramerization

45 GO:0000085 G2 phase of mitotic cell cycleGO:0001967 suckling behaviorGO:0002576 platelet degranulationGO:0006378 mRNA polyadenylationGO:0006417 regulation of translationGO:0006468 protein phosphorylationGO:0006878 cellular copper ion homeostasisGO:0006897 endocytosisGO:0006917 induction of apoptosisGO:0006979 response to oxidative stress

GO:0007155 cell adhesionGO:0007176 regulation of epidermal growth factor-activated receptor activityGO:0007219 Notch signaling pathwayGO:0007409 axonogenesisGO:0007596 blood coagulationGO:0007617 mating behaviorGO:0007626 locomotory behaviorGO:0008088 axon cargo transportGO:0008203 cholesterol metabolic processGO:0008344 adult locomotory behaviorGO:0008542 visual learningGO:0010468 regulation of gene expressionGO:0010952 positive regulation of peptidase activityGO:0010971 positive regulation of G2/M transition of mitotic cell cycleGO:0016199 axon midline choice point recognitionGO:0016322 neuron remodelingGO:0016358 dendrite developmentGO:0030168 platelet activationGO:0030198 extracellular matrix organizationGO:0030900 forebrain developmentGO:0031175 neuron projection developmentGO:0035235 ionotropic glutamate receptor signaling pathwayGO:0035872 nucleotide-binding domain, leucine rich repeat containing receptor signaling pathwayGO:0040014 regulation of multicellular organism growthGO:0043393 regulation of protein bindingGO:0045087 innate immune responseGO:0045665 negative regulation of neuron differentiationGO:0045931 positive regulation of mitotic cell cycleGO:0045944 positive regulation of transcription from RNA polymerase II promoterGO:0048669 collateral sprouting in absence of injuryGO:0050803 regulation of synapse structure and activityGO:0050885 neuromuscular process controlling balanceGO:0051124 synaptic growth at neuromuscular junctionGO:0051402 neuron apoptotic processGO:0051563 smooth endoplasmic reticulum calcium ion homeostasis

23 GO:0001889 liver developmentasparagine synthetase (glutamine-hydrolyzing) [Source:HGNC Symbol;Acc:753] GO:0006520 cellular amino acid metabolic processasparagine synthetase (glutamine-hydrolyzing) [Source:HGNC Symbol;Acc:753] GO:0006529 asparagine biosynthetic processasparagine synthetase (glutamine-hydrolyzing) [Source:HGNC Symbol;Acc:753] GO:0006541 glutamine metabolic processasparagine synthetase (glutamine-hydrolyzing) [Source:HGNC Symbol;Acc:753] GO:0006987 activation of signaling protein activity involved in unfolded protein responseasparagine synthetase (glutamine-hydrolyzing) [Source:HGNC Symbol;Acc:753] GO:0008152 metabolic processasparagine synthetase (glutamine-hydrolyzing) [Source:HGNC Symbol;Acc:753] GO:0008652 cellular amino acid biosynthetic processasparagine synthetase (glutamine-hydrolyzing) [Source:HGNC Symbol;Acc:753] GO:0009416 response to light stimulusasparagine synthetase (glutamine-hydrolyzing) [Source:HGNC Symbol;Acc:753] GO:0009612 response to mechanical stimulusasparagine synthetase (glutamine-hydrolyzing) [Source:HGNC Symbol;Acc:753] GO:0009636 response to toxic substanceasparagine synthetase (glutamine-hydrolyzing) [Source:HGNC Symbol;Acc:753] GO:0030968 endoplasmic reticulum unfolded protein response

asparagine synthetase (glutamine-hydrolyzing) [Source:HGNC Symbol;Acc:753] GO:0031427 response to methotrexateasparagine synthetase (glutamine-hydrolyzing) [Source:HGNC Symbol;Acc:753] GO:0031667 response to nutrient levelsasparagine synthetase (glutamine-hydrolyzing) [Source:HGNC Symbol;Acc:753] GO:0032354 response to follicle-stimulating hormone stimulusasparagine synthetase (glutamine-hydrolyzing) [Source:HGNC Symbol;Acc:753] GO:0032870 cellular response to hormone stimulusasparagine synthetase (glutamine-hydrolyzing) [Source:HGNC Symbol;Acc:753] GO:0034641 cellular nitrogen compound metabolic processasparagine synthetase (glutamine-hydrolyzing) [Source:HGNC Symbol;Acc:753] GO:0042149 cellular response to glucose starvationasparagine synthetase (glutamine-hydrolyzing) [Source:HGNC Symbol;Acc:753] GO:0043066 negative regulation of apoptotic processasparagine synthetase (glutamine-hydrolyzing) [Source:HGNC Symbol;Acc:753] GO:0043200 response to amino acid stimulusasparagine synthetase (glutamine-hydrolyzing) [Source:HGNC Symbol;Acc:753] GO:0044267 cellular protein metabolic processasparagine synthetase (glutamine-hydrolyzing) [Source:HGNC Symbol;Acc:753] GO:0044281 small molecule metabolic processasparagine synthetase (glutamine-hydrolyzing) [Source:HGNC Symbol;Acc:753] GO:0045931 positive regulation of mitotic cell cycleasparagine synthetase (glutamine-hydrolyzing) [Source:HGNC Symbol;Acc:753] GO:0070981 L-asparagine biosynthetic process

16 GO:0002026 regulation of the force of heart contractionATPase, Ca++ transporting, cardiac muscle, slow twitch 2 [Source:HGNC Symbol;Acc:812] GO:0006810 transportATPase, Ca++ transporting, cardiac muscle, slow twitch 2 [Source:HGNC Symbol;Acc:812] GO:0006812 cation transportATPase, Ca++ transporting, cardiac muscle, slow twitch 2 [Source:HGNC Symbol;Acc:812] GO:0006816 calcium ion transportATPase, Ca++ transporting, cardiac muscle, slow twitch 2 [Source:HGNC Symbol;Acc:812] GO:0006874 cellular calcium ion homeostasisATPase, Ca++ transporting, cardiac muscle, slow twitch 2 [Source:HGNC Symbol;Acc:812] GO:0006984 ER-nucleus signaling pathwayATPase, Ca++ transporting, cardiac muscle, slow twitch 2 [Source:HGNC Symbol;Acc:812] GO:0007155 cell adhesionATPase, Ca++ transporting, cardiac muscle, slow twitch 2 [Source:HGNC Symbol;Acc:812] GO:0007596 blood coagulationATPase, Ca++ transporting, cardiac muscle, slow twitch 2 [Source:HGNC Symbol;Acc:812] GO:0008544 epidermis developmentATPase, Ca++ transporting, cardiac muscle, slow twitch 2 [Source:HGNC Symbol;Acc:812] GO:0010460 positive regulation of heart rateATPase, Ca++ transporting, cardiac muscle, slow twitch 2 [Source:HGNC Symbol;Acc:812] GO:0034220 ion transmembrane transportATPase, Ca++ transporting, cardiac muscle, slow twitch 2 [Source:HGNC Symbol;Acc:812] GO:0045822 negative regulation of heart contractionATPase, Ca++ transporting, cardiac muscle, slow twitch 2 [Source:HGNC Symbol;Acc:812] GO:0055085 transmembrane transportATPase, Ca++ transporting, cardiac muscle, slow twitch 2 [Source:HGNC Symbol;Acc:812] GO:0055119 relaxation of cardiac muscleATPase, Ca++ transporting, cardiac muscle, slow twitch 2 [Source:HGNC Symbol;Acc:812] GO:0070296 sarcoplasmic reticulum calcium ion transportATPase, Ca++ transporting, cardiac muscle, slow twitch 2 [Source:HGNC Symbol;Acc:812] GO:0086036 regulation of cardiac muscle cell membrane potential

8 GO:0001558 regulation of cell growthBRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) [Source:HGNC Symbol;Acc:950] GO:0006464 cellular protein modification processBRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) [Source:HGNC Symbol;Acc:950] GO:0006511 ubiquitin-dependent protein catabolic processBRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) [Source:HGNC Symbol;Acc:950] GO:0008285 negative regulation of cell proliferationBRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) [Source:HGNC Symbol;Acc:950] GO:0016579 protein deubiquitinationBRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) [Source:HGNC Symbol;Acc:950] GO:0035522 monoubiquitinated histone H2A deubiquitinationBRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) [Source:HGNC Symbol;Acc:950] GO:0051726 regulation of cell cycleBRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) [Source:HGNC Symbol;Acc:950] GO:0071108 protein K48-linked deubiquitinationBRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) [Source:HGNC Symbol;Acc:950]BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) [Source:HGNC Symbol;Acc:950]BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) [Source:HGNC Symbol;Acc:950]BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) [Source:HGNC Symbol;Acc:950]BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) [Source:HGNC Symbol;Acc:950]BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) [Source:HGNC Symbol;Acc:950]BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) [Source:HGNC Symbol;Acc:950]BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) [Source:HGNC Symbol;Acc:950]BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) [Source:HGNC Symbol;Acc:950]BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) [Source:HGNC Symbol;Acc:950]

BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) [Source:HGNC Symbol;Acc:950]BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) [Source:HGNC Symbol;Acc:950]BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) [Source:HGNC Symbol;Acc:950]BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) [Source:HGNC Symbol;Acc:950]BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) [Source:HGNC Symbol;Acc:950]BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) [Source:HGNC Symbol;Acc:950]BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) [Source:HGNC Symbol;Acc:950]BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) [Source:HGNC Symbol;Acc:950]BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) [Source:HGNC Symbol;Acc:950]BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) [Source:HGNC Symbol;Acc:950]BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) [Source:HGNC Symbol;Acc:950]BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) [Source:HGNC Symbol;Acc:950]BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) [Source:HGNC Symbol;Acc:950]BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) [Source:HGNC Symbol;Acc:950]

9 GO:0001953 negative regulation of cell-matrix adhesioncalcium/calmodulin-dependent serine protein kinase (MAGUK family) [Source:HGNC Symbol;Acc:14GO:0006468 protein phosphorylationcalcium/calmodulin-dependent serine protein kinase (MAGUK family) [Source:HGNC Symbol;Acc:14GO:0007155 cell adhesioncalcium/calmodulin-dependent serine protein kinase (MAGUK family) [Source:HGNC Symbol;Acc:14GO:0010839 negative regulation of keratinocyte proliferationcalcium/calmodulin-dependent serine protein kinase (MAGUK family) [Source:HGNC Symbol;Acc:14GO:0045944 positive regulation of transcription from RNA polymerase II promotercalcium/calmodulin-dependent serine protein kinase (MAGUK family) [Source:HGNC Symbol;Acc:14GO:0061045 negative regulation of wound healingcalcium/calmodulin-dependent serine protein kinase (MAGUK family) [Source:HGNC Symbol;Acc:14GO:0070509 calcium ion importcalcium/calmodulin-dependent serine protein kinase (MAGUK family) [Source:HGNC Symbol;Acc:14GO:0090280 positive regulation of calcium ion importcalcium/calmodulin-dependent serine protein kinase (MAGUK family) [Source:HGNC Symbol;Acc:14GO:0090288 negative regulation of cellular response to growth factor stimuluscalcium/calmodulin-dependent serine protein kinase (MAGUK family) [Source:HGNC Symbol;Acc:1497]calcium/calmodulin-dependent serine protein kinase (MAGUK family) [Source:HGNC Symbol;Acc:1497]calcium/calmodulin-dependent serine protein kinase (MAGUK family) [Source:HGNC Symbol;Acc:1497]calcium/calmodulin-dependent serine protein kinase (MAGUK family) [Source:HGNC Symbol;Acc:1497]calcium/calmodulin-dependent serine protein kinase (MAGUK family) [Source:HGNC Symbol;Acc:1497]calcium/calmodulin-dependent serine protein kinase (MAGUK family) [Source:HGNC Symbol;Acc:1497]calcium/calmodulin-dependent serine protein kinase (MAGUK family) [Source:HGNC Symbol;Acc:1497]calcium/calmodulin-dependent serine protein kinase (MAGUK family) [Source:HGNC Symbol;Acc:1497]calcium/calmodulin-dependent serine protein kinase (MAGUK family) [Source:HGNC Symbol;Acc:1497]calcium/calmodulin-dependent serine protein kinase (MAGUK family) [Source:HGNC Symbol;Acc:1497]calcium/calmodulin-dependent serine protein kinase (MAGUK family) [Source:HGNC Symbol;Acc:1497]calcium/calmodulin-dependent serine protein kinase (MAGUK family) [Source:HGNC Symbol;Acc:1497]calcium/calmodulin-dependent serine protein kinase (MAGUK family) [Source:HGNC Symbol;Acc:1497]calcium/calmodulin-dependent serine protein kinase (MAGUK family) [Source:HGNC Symbol;Acc:1497]calcium/calmodulin-dependent serine protein kinase (MAGUK family) [Source:HGNC Symbol;Acc:1497]calcium/calmodulin-dependent serine protein kinase (MAGUK family) [Source:HGNC Symbol;Acc:1497]calcium/calmodulin-dependent serine protein kinase (MAGUK family) [Source:HGNC Symbol;Acc:1497]

7 GO:0006508 proteolysiscaspase 10, apoptosis-related cysteine peptidase [Source:HGNC Symbol;Acc:1500] GO:0006915 apoptotic processcaspase 10, apoptosis-related cysteine peptidase [Source:HGNC Symbol;Acc:1500] GO:0006917 induction of apoptosiscaspase 10, apoptosis-related cysteine peptidase [Source:HGNC Symbol;Acc:1500] GO:0042981 regulation of apoptotic processcaspase 10, apoptosis-related cysteine peptidase [Source:HGNC Symbol;Acc:1500] GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB cascadecaspase 10, apoptosis-related cysteine peptidase [Source:HGNC Symbol;Acc:1500] GO:0045087 innate immune response

caspase 10, apoptosis-related cysteine peptidase [Source:HGNC Symbol;Acc:1500] GO:0097190 apoptotic signaling pathwaycaspase 10, apoptosis-related cysteine peptidase [Source:HGNC Symbol;Acc:1500]caspase 10, apoptosis-related cysteine peptidase [Source:HGNC Symbol;Acc:1500]caspase 10, apoptosis-related cysteine peptidase [Source:HGNC Symbol;Acc:1500]caspase 10, apoptosis-related cysteine peptidase [Source:HGNC Symbol;Acc:1500]caspase 10, apoptosis-related cysteine peptidase [Source:HGNC Symbol;Acc:1500]caspase 10, apoptosis-related cysteine peptidase [Source:HGNC Symbol;Acc:1500]caspase 10, apoptosis-related cysteine peptidase [Source:HGNC Symbol;Acc:1500]caspase 10, apoptosis-related cysteine peptidase [Source:HGNC Symbol;Acc:1500]caspase 10, apoptosis-related cysteine peptidase [Source:HGNC Symbol;Acc:1500]

11 GO:0001701 in utero embryonic developmentchromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20153] GO:0006351 transcription, DNA-dependentchromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20153] GO:0030178 negative regulation of Wnt receptor signaling pathwaychromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20153] GO:0032508 DNA duplex unwindingchromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20153] GO:0043044 ATP-dependent chromatin remodelingchromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20153] GO:0043066 negative regulation of apoptotic processchromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20153] GO:0045892 negative regulation of transcription, DNA-dependentchromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20153] GO:0045893 positive regulation of transcription, DNA-dependentchromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20153] GO:0045944 positive regulation of transcription from RNA polymerase II promoterchromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20153] GO:0045945 positive regulation of transcription from RNA polymerase III promoterchromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20153] GO:0060070 canonical Wnt receptor signaling pathwaychromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20153]chromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20153]chromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20153]chromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20153]chromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20153]chromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20153]chromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20153]chromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20153]chromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20153]chromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20153]chromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20153]chromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20153]chromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20153]chromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20153]chromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20153]chromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20153]chromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20153]chromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20153]chromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20153]chromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20153]chromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20153]chromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20153]chromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20153]chromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:20153]

4 GO:0006635 fatty acid beta-oxidation

GO:0006853 carnitine shuttleGO:0044255 cellular lipid metabolic processGO:0044281 small molecule metabolic process

17 GO:0000096 sulfur amino acid metabolic processcystathionase (cystathionine gamma-lyase) [Source:HGNC Symbol;Acc:2501] GO:0000098 sulfur amino acid catabolic processcystathionase (cystathionine gamma-lyase) [Source:HGNC Symbol;Acc:2501] GO:0006534 cysteine metabolic processcystathionase (cystathionine gamma-lyase) [Source:HGNC Symbol;Acc:2501] GO:0008152 metabolic processcystathionase (cystathionine gamma-lyase) [Source:HGNC Symbol;Acc:2501] GO:0009058 biosynthetic processcystathionase (cystathionine gamma-lyase) [Source:HGNC Symbol;Acc:2501] GO:0018272 protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysinecystathionase (cystathionine gamma-lyase) [Source:HGNC Symbol;Acc:2501] GO:0019344 cysteine biosynthetic processcystathionase (cystathionine gamma-lyase) [Source:HGNC Symbol;Acc:2501] GO:0019346 transsulfurationcystathionase (cystathionine gamma-lyase) [Source:HGNC Symbol;Acc:2501] GO:0030968 endoplasmic reticulum unfolded protein responsecystathionase (cystathionine gamma-lyase) [Source:HGNC Symbol;Acc:2501] GO:0034641 cellular nitrogen compound metabolic processcystathionase (cystathionine gamma-lyase) [Source:HGNC Symbol;Acc:2501] GO:0043066 negative regulation of apoptotic processcystathionase (cystathionine gamma-lyase) [Source:HGNC Symbol;Acc:2501] GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB cascadecystathionase (cystathionine gamma-lyase) [Source:HGNC Symbol;Acc:2501] GO:0044281 small molecule metabolic processcystathionase (cystathionine gamma-lyase) [Source:HGNC Symbol;Acc:2501] GO:0044524 protein sulfhydrationcystathionase (cystathionine gamma-lyase) [Source:HGNC Symbol;Acc:2501] GO:0051092 positive regulation of NF-kappaB transcription factor activitycystathionase (cystathionine gamma-lyase) [Source:HGNC Symbol;Acc:2501] GO:0051289 protein homotetramerizationcystathionase (cystathionine gamma-lyase) [Source:HGNC Symbol;Acc:2501] GO:0070814 hydrogen sulfide biosynthetic processcystathionase (cystathionine gamma-lyase) [Source:HGNC Symbol;Acc:2501]cystathionase (cystathionine gamma-lyase) [Source:HGNC Symbol;Acc:2501]cystathionase (cystathionine gamma-lyase) [Source:HGNC Symbol;Acc:2501]cystathionase (cystathionine gamma-lyase) [Source:HGNC Symbol;Acc:2501]cystathionase (cystathionine gamma-lyase) [Source:HGNC Symbol;Acc:2501]cystathionase (cystathionine gamma-lyase) [Source:HGNC Symbol;Acc:2501]

cystathionase (cystathionine gamma-lyase) [Source:HGNC Symbol;Acc:2501]11 GO:0006520 cellular amino acid metabolic process

GO:0006749 glutathione metabolic processGO:0007420 brain developmentGO:0007616 long-term memoryGO:0007625 grooming behaviorGO:0007628 adult walking behaviorGO:0008542 visual learningGO:0015811 L-cystine transportGO:0046034 ATP metabolic processGO:0048058 compound eye corneal lens developmentGO:0050890 cognition

47 GO:0000165 MAPK cascadeGO:0000186 activation of MAPKK activityGO:0000902 cell morphogenesisGO:0001503 ossificationGO:0001892 embryonic placenta developmentGO:0001942 hair follicle developmentGO:0006468 protein phosphorylationGO:0006950 response to stressGO:0007165 signal transductionGO:0007166 cell surface receptor signaling pathwayGO:0007169 transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007173 epidermal growth factor receptor signaling pathwayGO:0007202 activation of phospholipase C activityGO:0007411 axon guidanceGO:0007435 salivary gland morphogenesisGO:0008283 cell proliferationGO:0008284 positive regulation of cell proliferationGO:0008543 fibroblast growth factor receptor signaling pathwayGO:0008544 epidermis developmentGO:0016337 cell-cell adhesionGO:0021795 cerebral cortex cell migrationGO:0030335 positive regulation of cell migrationGO:0031659 positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in GGO:0035413 positive regulation of catenin import into nucleusGO:0042059 negative regulation of epidermal growth factor receptor signaling pathway

GO:0042127 regulation of cell proliferationGO:0042177 negative regulation of protein catabolic processGO:0042327 positive regulation of phosphorylationGO:0043006 activation of phospholipase A2 activity by calcium-mediated signalingGO:0043066 negative regulation of apoptotic processGO:0043406 positive regulation of MAP kinase activityGO:0045087 innate immune responseGO:0045429 positive regulation of nitric oxide biosynthetic processGO:0045739 positive regulation of DNA repairGO:0045740 positive regulation of DNA replicationGO:0046777 protein autophosphorylationGO:0048011 neurotrophin TRK receptor signaling pathwayGO:0048015 phosphatidylinositol-mediated signalingGO:0048146 positive regulation of fibroblast proliferationGO:0048546 digestive tract morphogenesisGO:0050679 positive regulation of epithelial cell proliferationGO:0050730 regulation of peptidyl-tyrosine phosphorylationGO:0050999 regulation of nitric-oxide synthase activityGO:0051205 protein insertion into membraneGO:0051897 positive regulation of protein kinase B signaling cascadeGO:0060571 morphogenesis of an epithelial foldGO:0070141 response to UV-A

7 GO:0006886 intracellular protein transportGO:0006200 ATP catabolic processGO:0007155 cell adhesionGO:0007186 G-protein coupled receptor signaling pathwayGO:0007596 blood coagulationGO:0009181 purine ribonucleoside diphosphate catabolic processGO:0030168 platelet activation

25 GO:0006355 regulation of transcription, DNA-dependentGO:0006629 lipid metabolic processGO:0006633 fatty acid biosynthetic processGO:0006636 unsaturated fatty acid biosynthetic processGO:0006950 response to stressGO:0007267 cell-cell signalingGO:0007568 agingGO:0007584 response to nutrientGO:0008654 phospholipid biosynthetic process

GO:0009267 cellular response to starvationGO:0009744 response to sucrose stimulusGO:0010033 response to organic substanceGO:0014070 response to organic cyclic compoundGO:0019369 arachidonic acid metabolic processGO:0022900 electron transport chainGO:0032868 response to insulin stimulusGO:0033189 response to vitamin AGO:0033559 unsaturated fatty acid metabolic processGO:0036109 alpha-linolenic acid metabolic processGO:0043651 linoleic acid metabolic processGO:0044255 cellular lipid metabolic processGO:0044281 small molecule metabolic processGO:0045595 regulation of cell differentiationGO:0046456 icosanoid biosynthetic processGO:0055114 oxidation-reduction process

6 GO:0006766 vitamin metabolic processGO:0006767 water-soluble vitamin metabolic processGO:0006777 Mo-molybdopterin cofactor biosynthetic processGO:0007529 establishment of synaptic specificity at neuromuscular junctionGO:0032324 molybdopterin cofactor biosynthetic processGO:0044281 small molecule metabolic process

12 GO:0006520 cellular amino acid metabolic processGO:0006750 glutathione biosynthetic processGO:0006805 xenobiotic metabolic processGO:0006979 response to oxidative stressGO:0007399 nervous system developmentGO:0007568 agingGO:0009410 response to xenobiotic stimulusGO:0031667 response to nutrient levelsGO:0034612 response to tumor necrosis factorGO:0043200 response to amino acid stimulusGO:0044281 small molecule metabolic processGO:0046686 response to cadmium ion

11 GO:0006631 fatty acid metabolic processhydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional prote GO:0006635 fatty acid beta-oxidationhydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional prote GO:0006644 phospholipid metabolic processhydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional prote GO:0008152 metabolic processhydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional prote GO:0032868 response to insulin stimulus

hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional prote GO:0035965 cardiolipin acyl-chain remodelinghydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional prote GO:0042493 response to drughydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional prote GO:0044255 cellular lipid metabolic processhydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional prote GO:0044281 small molecule metabolic processhydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional prote GO:0046474 glycerophospholipid biosynthetic processhydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional prote GO:0055114 oxidation-reduction processhydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit [Source:HGNC Symbol;Acc:4801]hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit [Source:HGNC Symbol;Acc:4801]hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit [Source:HGNC Symbol;Acc:4801]hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit [Source:HGNC Symbol;Acc:4801]hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit [Source:HGNC Symbol;Acc:4801]hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit [Source:HGNC Symbol;Acc:4801]hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit [Source:HGNC Symbol;Acc:4801]hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit [Source:HGNC Symbol;Acc:4801]hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit [Source:HGNC Symbol;Acc:4801]hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit [Source:HGNC Symbol;Acc:4801]hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit [Source:HGNC Symbol;Acc:4801]hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit [Source:HGNC Symbol;Acc:4801]hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit [Source:HGNC Symbol;Acc:4801]hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit [Source:HGNC Symbol;Acc:4801]hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit [Source:HGNC Symbol;Acc:4801]hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit [Source:HGNC Symbol;Acc:4801]hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit [Source:HGNC Symbol;Acc:4801]hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit [Source:HGNC Symbol;Acc:4801]hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit [Source:HGNC Symbol;Acc:4801]hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit [Source:HGNC Symbol;Acc:4801]

26 GO:0006695 cholesterol biosynthetic processGO:0006743 ubiquinone metabolic processGO:0007568 agingGO:0007584 response to nutrientGO:0008284 positive regulation of cell proliferationGO:0008299 isoprenoid biosynthetic processGO:0008542 visual learningGO:0009790 embryo developmentGO:0010664 negative regulation of striated muscle cell apoptotic processGO:0010666 positive regulation of cardiac muscle cell apoptotic processGO:0015936 coenzyme A metabolic processGO:0032874 positive regulation of stress-activated MAPK cascadeGO:0043066 negative regulation of apoptotic processGO:0043407 negative regulation of MAP kinase activityGO:0044255 cellular lipid metabolic processGO:0044281 small molecule metabolic processGO:0045445 myoblast differentiationGO:0045471 response to ethanolGO:0045908 negative regulation of vasodilationGO:0048643 positive regulation of skeletal muscle tissue development

GO:0048661 positive regulation of smooth muscle cell proliferationGO:0051262 protein tetramerizationGO:0055114 oxidation-reduction processGO:0061045 negative regulation of wound healingGO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulusGO:0070374 positive regulation of ERK1 and ERK2 cascade

24 GO:0006006 glucose metabolic processGO:0006644 phospholipid metabolic processGO:0006661 phosphatidylinositol biosynthetic processGO:0006897 endocytosisGO:0007015 actin filament organizationGO:0007155 cell adhesionGO:0007420 brain developmentGO:0008156 negative regulation of DNA replicationGO:0008285 negative regulation of cell proliferationGO:0009791 post-embryonic developmentGO:0010629 negative regulation of gene expressionGO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathwayGO:0010977 negative regulation of neuron projection developmentGO:0032868 response to insulin stimulusGO:0032957 inositol trisphosphate metabolic processGO:0042493 response to drugGO:0043407 negative regulation of MAP kinase activityGO:0043569 negative regulation of insulin-like growth factor receptor signaling pathwayGO:0043647 inositol phosphate metabolic processGO:0044255 cellular lipid metabolic processGO:0044281 small molecule metabolic processGO:0046627 negative regulation of insulin receptor signaling pathwayGO:0046856 phosphatidylinositol dephosphorylationGO:0097178 ruffle assembly

5 GO:0006811 ion transportpotassium voltage-gated channel, Shaw-related subfamily, member 1 [Source:HGNC Symbol;Acc:62GO:0006813 potassium ion transportpotassium voltage-gated channel, Shaw-related subfamily, member 1 [Source:HGNC Symbol;Acc:62GO:0007268 synaptic transmissionpotassium voltage-gated channel, Shaw-related subfamily, member 1 [Source:HGNC Symbol;Acc:62GO:0051260 protein homooligomerizationpotassium voltage-gated channel, Shaw-related subfamily, member 1 [Source:HGNC Symbol;Acc:62GO:0055085 transmembrane transport

7 GO:0005975 carbohydrate metabolic processGO:0006090 pyruvate metabolic processGO:0006096 glycolysisGO:0031668 cellular response to extracellular stimulusGO:0044262 cellular carbohydrate metabolic processGO:0044281 small molecule metabolic process

GO:0055114 oxidation-reduction process

50 GO:0001934 positive regulation of protein phosphorylationmechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942] GO:0001938 positive regulation of endothelial cell proliferationmechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942] GO:0005979 regulation of glycogen biosynthetic processmechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942] GO:0006109 regulation of carbohydrate metabolic processmechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942] GO:0006468 protein phosphorylationmechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942] GO:0006950 response to stressmechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942] GO:0007165 signal transductionmechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942] GO:0007173 epidermal growth factor receptor signaling pathwaymechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942] GO:0007281 germ cell developmentmechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942] GO:0007584 response to nutrientmechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942] GO:0008286 insulin receptor signaling pathwaymechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942] GO:0008543 fibroblast growth factor receptor signaling pathwaymechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942] GO:0010507 negative regulation of autophagymechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942] GO:0010592 positive regulation of lamellipodium assemblymechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942] GO:0010628 positive regulation of gene expressionmechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942] GO:0010831 positive regulation of myotube differentiationmechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942] GO:0016049 cell growthmechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942] GO:0016242 negative regulation of macroautophagymechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942] GO:0016310 phosphorylationmechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942] GO:0018105 peptidyl-serine phosphorylationmechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942] GO:0018107 peptidyl-threonine phosphorylationmechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942] GO:0030030 cell projection organizationmechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942] GO:0030163 protein catabolic processmechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942] GO:0030838 positive regulation of actin filament polymerizationmechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942] GO:0031295 T cell costimulationmechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942] GO:0031529 ruffle organizationmechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942] GO:0031669 cellular response to nutrient levelsmechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942] GO:0031929 TOR signaling cascademechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942] GO:0031998 regulation of fatty acid beta-oxidationmechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942] GO:0032095 regulation of response to foodmechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942] GO:0032314 regulation of Rac GTPase activitymechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942] GO:0032868 response to insulin stimulusmechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942] GO:0032956 regulation of actin cytoskeleton organizationmechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942] GO:0040007 growthmechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942] GO:0043200 response to amino acid stimulusmechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942] GO:0043610 regulation of carbohydrate utilizationmechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942] GO:0045087 innate immune responsemechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942] GO:0045727 positive regulation of translationmechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942] GO:0045792 negative regulation of cell sizemechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942] GO:0045859 regulation of protein kinase activity

mechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942] GO:0045945 positive regulation of transcription from RNA polymerase III promotermechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942] GO:0046777 protein autophosphorylationmechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942] GO:0046889 positive regulation of lipid biosynthetic processmechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942] GO:0048011 neurotrophin TRK receptor signaling pathwaymechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942] GO:0048015 phosphatidylinositol-mediated signalingmechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942] GO:0050731 positive regulation of peptidyl-tyrosine phosphorylationmechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942] GO:0051496 positive regulation of stress fiber assemblymechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942] GO:0051534 negative regulation of NFAT protein import into nucleusmechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942] GO:0051897 positive regulation of protein kinase B signaling cascademechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942] GO:0071456 cellular response to hypoxia

10 GO:0006120 mitochondrial electron transport, NADH to ubiqNADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) [Source: GO:0006915 apoptotic processNADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) [Source: GO:0022904 respiratory electron transport chainNADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) [Source: GO:0042773 ATP synthesis coupled electron transportNADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) [Source: GO:0044281 small molecule metabolic processNADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) [Source: GO:0045333 cellular respirationNADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) [Source: GO:0046034 ATP metabolic processNADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) [Source: GO:0051881 regulation of mitochondrial membrane potentialNADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) [Source: GO:0055114 oxidation-reduction processNADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) [Source: GO:0072593 reactive oxygen species metabolic processNADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) [Source:HGNC Symbol;Acc:7707]NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) [Source:HGNC Symbol;Acc:7707]NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) [Source:HGNC Symbol;Acc:7707]NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) [Source:HGNC Symbol;Acc:7707]NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) [Source:HGNC Symbol;Acc:7707]NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) [Source:HGNC Symbol;Acc:7707]NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) [Source:HGNC Symbol;Acc:7707]NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) [Source:HGNC Symbol;Acc:7707]NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) [Source:HGNC Symbol;Acc:7707]

4 GO:0006120 mitochondrial electron transport, NADH to ubiqNADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa [Source:HGNC Symbol;Acc:7716] GO:0022904 respiratory electron transport chainNADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa [Source:HGNC Symbol;Acc:7716] GO:0044281 small molecule metabolic processNADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa [Source:HGNC Symbol;Acc:7716] GO:0055114 oxidation-reduction processNADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa [Source:HGNC Symbol;Acc:7716]NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa [Source:HGNC Symbol;Acc:7716]NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa [Source:HGNC Symbol;Acc:7716]NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa [Source:HGNC Symbol;Acc:7716]NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa [Source:HGNC Symbol;Acc:7716]NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa [Source:HGNC Symbol;Acc:7716]NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa [Source:HGNC Symbol;Acc:7716]NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa [Source:HGNC Symbol;Acc:7716]NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa [Source:HGNC Symbol;Acc:7716]NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa [Source:HGNC Symbol;Acc:7716]NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa [Source:HGNC Symbol;Acc:7716]NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa [Source:HGNC Symbol;Acc:7716]NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa [Source:HGNC Symbol;Acc:7716]

NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa [Source:HGNC Symbol;Acc:7716]16 GO:0006111 regulation of gluconeogenesis

nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) [Source:HGNC Symbol;AGO:0006351 transcription, DNA-dependentnuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) [Source:HGNC Symbol;AGO:0006355 regulation of transcription, DNA-dependentnuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) [Source:HGNC Symbol;AGO:0006366 transcription from RNA polymerase II promoternuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) [Source:HGNC Symbol;AGO:0006367 transcription initiation from RNA polymerase II promoternuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) [Source:HGNC Symbol;AGO:0007165 signal transductionnuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) [Source:HGNC Symbol;AGO:0008211 glucocorticoid metabolic processnuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) [Source:HGNC Symbol;AGO:0010467 gene expressionnuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) [Source:HGNC Symbol;AGO:0016568 chromatin modificationnuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) [Source:HGNC Symbol;AGO:0030325 adrenal gland developmentnuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) [Source:HGNC Symbol;AGO:0031946 regulation of glucocorticoid biosynthetic processnuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) [Source:HGNC Symbol;AGO:0042921 glucocorticoid receptor signaling pathwaynuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) [Source:HGNC Symbol;AGO:0043401 steroid hormone mediated signaling pathwaynuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) [Source:HGNC Symbol;AGO:0043402 glucocorticoid mediated signaling pathwaynuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) [Source:HGNC Symbol;AGO:0043525 positive regulation of neuron apoptotic processnuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) [Source:HGNC Symbol;AGO:0060603 mammary gland duct morphogenesis

22 GO:0000059 protein import into nucleus, dockingGO:0000059 protein import into nucleus, dockingGO:0000087 M phase of mitotic cell cycleGO:0000090 mitotic anaphaseGO:0000236 mitotic prometaphaseGO:0000278 mitotic cell cycleGO:0005975 carbohydrate metabolic processGO:0006260 DNA replicationGO:0006810 transportGO:0006913 nucleocytoplasmic transportGO:0006999 nuclear pore organizationGO:0008645 hexose transportGO:0010827 regulation of glucose transportGO:0015758 glucose transportGO:0016032 viral reproductionGO:0019048 virus-host interactionGO:0019221 cytokine-mediated signaling pathwayGO:0022415 viral reproductive processGO:0044281 small molecule metabolic processGO:0051028 mRNA transportGO:0051292 nuclear pore complex assemblyGO:0055085 transmembrane transport

9 GO:0006559 L-phenylalanine catabolic processGO:0008152 metabolic processGO:0008652 cellular amino acid biosynthetic processGO:0009072 aromatic amino acid family metabolic processGO:0034641 cellular nitrogen compound metabolic processGO:0042136 neurotransmitter biosynthetic processGO:0042423 catecholamine biosynthetic processGO:0044281 small molecule metabolic processGO:0055114 oxidation-reduction process

9 GO:0005975 carbohydrate metabolic processGO:0006002 fructose 6-phosphate metabolic processGO:0006006 glucose metabolic processGO:0006096 glycolysisGO:0032024 positive regulation of insulin secretionGO:0042593 glucose homeostasisGO:0044281 small molecule metabolic processGO:0046716 muscle cell homeostasisGO:0051259 protein oligomerization

8 GO:0005975 carbohydrate metabolic processGO:0005978 glycogen biosynthetic processGO:0005980 glycogen catabolic processGO:0006006 glucose metabolic processGO:0006094 gluconeogenesisGO:0006096 glycolysisGO:0019388 galactose catabolic processGO:0044281 small molecule metabolic process

1 GO:0006493 protein O-linked glycosylation

3 GO:0000413 protein peptidyl-prolyl isomerizationGO:0006457 protein foldingGO:0030198 extracellular matrix organization

83 GO:0000165 MAPK cascadeGO:0000302 response to reactive oxygen speciesGO:0001525 angiogenesisGO:0001556 oocyte maturationGO:0001666 response to hypoxiaGO:0001954 positive regulation of cell-matrix adhesionGO:0002040 sprouting angiogenesisGO:0002315 marginal zone B cell differentiationGO:0006461 protein complex assemblyGO:0006468 protein phosphorylationGO:0006915 apoptotic processGO:0006950 response to stressGO:0006970 response to osmotic stressGO:0007015 actin filament organizationGO:0007155 cell adhesionGO:0007165 signal transductionGO:0007166 cell surface receptor signaling pathwayGO:0007172 signal complex assemblyGO:0007173 epidermal growth factor receptor signaling pathwayGO:0007204 elevation of cytosolic calcium ion concentrationGO:0007229 integrin-mediated signaling pathwayGO:0008284 positive regulation of cell proliferationGO:0008285 negative regulation of cell proliferationGO:0008360 regulation of cell shapeGO:0009612 response to mechanical stimulusGO:0009725 response to hormone stimulusGO:0009749 response to glucose stimulusGO:0010226 response to lithium ionGO:0010243 response to organic nitrogenGO:0010595 positive regulation of endothelial cell migrationGO:0010752 regulation of cGMP-mediated signalingGO:0010758 regulation of macrophage chemotaxisGO:0010976 positive regulation of neuron projection developmentGO:0014009 glial cell proliferationGO:0018108 peptidyl-tyrosine phosphorylationGO:0030154 cell differentiationGO:0030155 regulation of cell adhesionGO:0030279 negative regulation of ossificationGO:0030307 positive regulation of cell growthGO:0030335 positive regulation of cell migrationGO:0030502 negative regulation of bone mineralizationGO:0030826 regulation of cGMP biosynthetic processGO:0030838 positive regulation of actin filament polymerization

GO:0031175 neuron projection developmentGO:0032863 activation of Rac GTPase activityGO:0032960 regulation of inositol trisphosphate biosynthetic processGO:0033209 tumor necrosis factor-mediated signaling pathwayGO:0042220 response to cocaineGO:0042493 response to drugGO:0042542 response to hydrogen peroxideGO:0042976 activation of Janus kinase activityGO:0043066 negative regulation of apoptotic processGO:0043149 stress fiber assemblyGO:0043267 negative regulation of potassium ion transportGO:0043507 positive regulation of JUN kinase activityGO:0043534 blood vessel endothelial cell migrationGO:0043552 positive regulation of phosphatidylinositol 3-kinase activityGO:0045428 regulation of nitric oxide biosynthetic processGO:0045453 bone resorptionGO:0045471 response to ethanolGO:0045638 negative regulation of myeloid cell differentiationGO:0045727 positive regulation of translationGO:0045766 positive regulation of angiogenesisGO:0045860 positive regulation of protein kinase activityGO:0046330 positive regulation of JNK cascadeGO:0046777 protein autophosphorylationGO:0048010 vascular endothelial growth factor receptor signaling pathwayGO:0048041 focal adhesion assemblyGO:0050731 positive regulation of peptidyl-tyrosine phosphorylationGO:0050848 regulation of calcium-mediated signalingGO:0051000 positive regulation of nitric-oxide synthase activityGO:0051279 regulation of release of sequestered calcium ion into cytosolGO:0051591 response to cAMPGO:0051592 response to calcium ionGO:0070098 chemokine-mediated signaling pathwayGO:0070374 positive regulation of ERK1 and ERK2 cascadeGO:0071300 cellular response to retinoic acidGO:2000058 regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic processGO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic processGO:2000114 regulation of establishment of cell polarityGO:2000249 regulation of actin cytoskeleton reorganizationGO:2000379 positive regulation of reactive oxygen species metabolic processGO:2000538 positive regulation of B cell chemotaxis

8 GO:0006090 pyruvate metabolic processsolute carrier family 16, member 1 (monocarboxylic acid transporter 1) [Source:HGNC Symbol;Acc: GO:0007596 blood coagulationsolute carrier family 16, member 1 (monocarboxylic acid transporter 1) [Source:HGNC Symbol;Acc: GO:0015711 organic anion transportsolute carrier family 16, member 1 (monocarboxylic acid transporter 1) [Source:HGNC Symbol;Acc: GO:0015718 monocarboxylic acid transportsolute carrier family 16, member 1 (monocarboxylic acid transporter 1) [Source:HGNC Symbol;Acc: GO:0015728 mevalonate transportsolute carrier family 16, member 1 (monocarboxylic acid transporter 1) [Source:HGNC Symbol;Acc: GO:0044281 small molecule metabolic process

solute carrier family 16, member 1 (monocarboxylic acid transporter 1) [Source:HGNC Symbol;Acc: GO:0050900 leukocyte migrationsolute carrier family 16, member 1 (monocarboxylic acid transporter 1) [Source:HGNC Symbol;Acc: GO:0055085 transmembrane transport

9 GO:0005975 carbohydrate metabolic processsolute carrier family 25 (aspartate/glutamate carrier), member 12 [Source:HGNC Symbol;Acc:10982GO:0006006 glucose metabolic processsolute carrier family 25 (aspartate/glutamate carrier), member 12 [Source:HGNC Symbol;Acc:10982GO:0006094 gluconeogenesissolute carrier family 25 (aspartate/glutamate carrier), member 12 [Source:HGNC Symbol;Acc:10982GO:0015810 aspartate transportsolute carrier family 25 (aspartate/glutamate carrier), member 12 [Source:HGNC Symbol;Acc:10982GO:0015813 L-glutamate transportsolute carrier family 25 (aspartate/glutamate carrier), member 12 [Source:HGNC Symbol;Acc:10982GO:0043490 malate-aspartate shuttlesolute carrier family 25 (aspartate/glutamate carrier), member 12 [Source:HGNC Symbol;Acc:10982GO:0044281 small molecule metabolic processsolute carrier family 25 (aspartate/glutamate carrier), member 12 [Source:HGNC Symbol;Acc:10982GO:0051592 response to calcium ionsolute carrier family 25 (aspartate/glutamate carrier), member 12 [Source:HGNC Symbol;Acc:10982GO:0055085 transmembrane transport

10 GO:0005975 carbohydrate metabolic processsolute carrier family 25 (aspartate/glutamate carrier), member 13 [Source:HGNC Symbol;Acc:10983GO:0006006 glucose metabolic processsolute carrier family 25 (aspartate/glutamate carrier), member 13 [Source:HGNC Symbol;Acc:10983GO:0006094 gluconeogenesissolute carrier family 25 (aspartate/glutamate carrier), member 13 [Source:HGNC Symbol;Acc:10983GO:0006754 ATP biosynthetic processsolute carrier family 25 (aspartate/glutamate carrier), member 13 [Source:HGNC Symbol;Acc:10983GO:0006810 transportsolute carrier family 25 (aspartate/glutamate carrier), member 13 [Source:HGNC Symbol;Acc:10983GO:0015810 aspartate transportsolute carrier family 25 (aspartate/glutamate carrier), member 13 [Source:HGNC Symbol;Acc:10983GO:0015813 L-glutamate transportsolute carrier family 25 (aspartate/glutamate carrier), member 13 [Source:HGNC Symbol;Acc:10983GO:0043490 malate-aspartate shuttlesolute carrier family 25 (aspartate/glutamate carrier), member 13 [Source:HGNC Symbol;Acc:10983GO:0044281 small molecule metabolic processsolute carrier family 25 (aspartate/glutamate carrier), member 13 [Source:HGNC Symbol;Acc:10983GO:0045333 cellular respirationsolute carrier family 25 (aspartate/glutamate carrier), member 13 [Source:HGNC Symbol;Acc:10983]solute carrier family 25 (aspartate/glutamate carrier), member 13 [Source:HGNC Symbol;Acc:10983]solute carrier family 25 (aspartate/glutamate carrier), member 13 [Source:HGNC Symbol;Acc:10983]solute carrier family 25 (aspartate/glutamate carrier), member 13 [Source:HGNC Symbol;Acc:10983]

2 GO:0006091 generation of precursor metabolites and energysolute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 [Source:HGNC Symbo GO:0006810 transportsolute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 [Source:HGNC Symbol;Acc:10989]solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 [Source:HGNC Symbol;Acc:10989]solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 [Source:HGNC Symbol;Acc:10989]solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 [Source:HGNC Symbol;Acc:10989]solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 [Source:HGNC Symbol;Acc:10989]solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 [Source:HGNC Symbol;Acc:10989]solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 [Source:HGNC Symbol;Acc:10989]solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 [Source:HGNC Symbol;Acc:10989]

68 GO:0001774 microglial cell activationsynuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138] GO:0001921 positive regulation of receptor recyclingsynuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138] GO:0001933 negative regulation of protein phosphorylationsynuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138] GO:0001956 positive regulation of neurotransmitter secretionsynuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138] GO:0001963 synaptic transmission, dopaminergicsynuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138] GO:0006631 fatty acid metabolic processsynuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138] GO:0006638 neutral lipid metabolic processsynuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138] GO:0006644 phospholipid metabolic processsynuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138] GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic processsynuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138] GO:0007006 mitochondrial membrane organizationsynuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138] GO:0007268 synaptic transmission

synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138] GO:0007568 agingsynuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138] GO:0008344 adult locomotory behaviorsynuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138] GO:0010040 response to iron(II) ionsynuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138] GO:0010517 regulation of phospholipase activitysynuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138] GO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathwaysynuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138] GO:0014048 regulation of glutamate secretionsynuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138] GO:0014059 regulation of dopamine secretionsynuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138] GO:0016044 cellular membrane organizationsynuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138] GO:0031115 negative regulation of microtubule polymerizationsynuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138] GO:0031623 receptor internalizationsynuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138] GO:0031648 protein destabilizationsynuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138] GO:0032026 response to magnesium ionsynuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138] GO:0032410 negative regulation of transporter activitysynuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138] GO:0032496 response to lipopolysaccharidesynuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138] GO:0032769 negative regulation of monooxygenase activitysynuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138] GO:0033138 positive regulation of peptidyl-serine phosphorylationsynuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138] GO:0034341 response to interferon-gammasynuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138] GO:0034599 cellular response to oxidative stresssynuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138] GO:0035067 negative regulation of histone acetylationsynuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138] GO:0040012 regulation of locomotionsynuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138] GO:0042220 response to cocainesynuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138] GO:0042416 dopamine biosynthetic processsynuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138] GO:0042417 dopamine metabolic processsynuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138] GO:0042493 response to drugsynuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138] GO:0042775 mitochondrial ATP synthesis coupled electron transportsynuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138] GO:0043030 regulation of macrophage activationsynuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138] GO:0043066 negative regulation of apoptotic processsynuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138] GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic processsynuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138] GO:0043206 extracellular fibril organizationsynuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138] GO:0043524 negative regulation of neuron apoptotic processsynuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138] GO:0044344 cellular response to fibroblast growth factor stimulussynuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138] GO:0045807 positive regulation of endocytosissynuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138] GO:0045920 negative regulation of exocytosissynuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138] GO:0045963 negative regulation of dopamine metabolic processsynuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138] GO:0046928 regulation of neurotransmitter secretionsynuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138] GO:0048148 behavioral response to cocainesynuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138] GO:0048168 regulation of neuronal synaptic plasticitysynuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138] GO:0048169 regulation of long-term neuronal synaptic plasticitysynuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138] GO:0048488 synaptic vesicle endocytosissynuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138] GO:0048489 synaptic vesicle transportsynuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138] GO:0050806 positive regulation of synaptic transmissionsynuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138] GO:0050808 synapse organizationsynuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138] GO:0050812 regulation of acyl-CoA biosynthetic processsynuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138] GO:0051281 positive regulation of release of sequestered calcium ion into cytosolsynuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138] GO:0051583 dopamine uptake involved in synaptic transmissionsynuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138] GO:0051585 negative regulation of dopamine uptake involved in synaptic transmission

synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138] GO:0051612 negative regulation of serotonin uptakesynuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138] GO:0051622 negative regulation of norepinephrine uptakesynuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138] GO:0055114 oxidation-reduction processsynuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138] GO:0060079 regulation of excitatory postsynaptic membrane potentialsynuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138] GO:0060291 long-term synaptic potentiationsynuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138] GO:0060732 positive regulation of inositol phosphate biosynthetic processsynuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138] GO:0070495 negative regulation of thrombin receptor signaling pathwaysynuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138] GO:0070555 response to interleukin-1synuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138] GO:0071280 cellular response to copper ionsynuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138] GO:0071872 cellular response to epinephrine stimulussynuclein, alpha (non A4 component of amyloid precursor) [Source:HGNC Symbol;Acc:11138] GO:0071902 positive regulation of protein serine/threonine kinase activity

6 GO:0006508 proteolysisspastic paraplegia 7 (pure and complicated autosomal recessive) [Source:HGNC Symbol;Acc:11237] GO:0007005 mitochondrion organizationspastic paraplegia 7 (pure and complicated autosomal recessive) [Source:HGNC Symbol;Acc:11237] GO:0007399 nervous system developmentspastic paraplegia 7 (pure and complicated autosomal recessive) [Source:HGNC Symbol;Acc:11237] GO:0008089 anterograde axon cargo transportspastic paraplegia 7 (pure and complicated autosomal recessive) [Source:HGNC Symbol;Acc:11237] GO:0008219 cell deathspastic paraplegia 7 (pure and complicated autosomal recessive) [Source:HGNC Symbol;Acc:11237] GO:0030163 protein catabolic processspastic paraplegia 7 (pure and complicated autosomal recessive) [Source:HGNC Symbol;Acc:11237]spastic paraplegia 7 (pure and complicated autosomal recessive) [Source:HGNC Symbol;Acc:11237]spastic paraplegia 7 (pure and complicated autosomal recessive) [Source:HGNC Symbol;Acc:11237]spastic paraplegia 7 (pure and complicated autosomal recessive) [Source:HGNC Symbol;Acc:11237]spastic paraplegia 7 (pure and complicated autosomal recessive) [Source:HGNC Symbol;Acc:11237]spastic paraplegia 7 (pure and complicated autosomal recessive) [Source:HGNC Symbol;Acc:11237]spastic paraplegia 7 (pure and complicated autosomal recessive) [Source:HGNC Symbol;Acc:11237]spastic paraplegia 7 (pure and complicated autosomal recessive) [Source:HGNC Symbol;Acc:11237]spastic paraplegia 7 (pure and complicated autosomal recessive) [Source:HGNC Symbol;Acc:11237]spastic paraplegia 7 (pure and complicated autosomal recessive) [Source:HGNC Symbol;Acc:11237]spastic paraplegia 7 (pure and complicated autosomal recessive) [Source:HGNC Symbol;Acc:11237]spastic paraplegia 7 (pure and complicated autosomal recessive) [Source:HGNC Symbol;Acc:11237]spastic paraplegia 7 (pure and complicated autosomal recessive) [Source:HGNC Symbol;Acc:11237]spastic paraplegia 7 (pure and complicated autosomal recessive) [Source:HGNC Symbol;Acc:11237]spastic paraplegia 7 (pure and complicated autosomal recessive) [Source:HGNC Symbol;Acc:11237]spastic paraplegia 7 (pure and complicated autosomal recessive) [Source:HGNC Symbol;Acc:11237]spastic paraplegia 7 (pure and complicated autosomal recessive) [Source:HGNC Symbol;Acc:11237]spastic paraplegia 7 (pure and complicated autosomal recessive) [Source:HGNC Symbol;Acc:11237]spastic paraplegia 7 (pure and complicated autosomal recessive) [Source:HGNC Symbol;Acc:11237]spastic paraplegia 7 (pure and complicated autosomal recessive) [Source:HGNC Symbol;Acc:11237]spastic paraplegia 7 (pure and complicated autosomal recessive) [Source:HGNC Symbol;Acc:11237]spastic paraplegia 7 (pure and complicated autosomal recessive) [Source:HGNC Symbol;Acc:11237]spastic paraplegia 7 (pure and complicated autosomal recessive) [Source:HGNC Symbol;Acc:11237]spastic paraplegia 7 (pure and complicated autosomal recessive) [Source:HGNC Symbol;Acc:11237]

6 GO:0006099 tricarboxylic acid cyclesuccinate-CoA ligase, ADP-forming, beta subunit [Source:HGNC Symbol;Acc:11448] GO:0006104 succinyl-CoA metabolic processsuccinate-CoA ligase, ADP-forming, beta subunit [Source:HGNC Symbol;Acc:11448] GO:0006105 succinate metabolic processsuccinate-CoA ligase, ADP-forming, beta subunit [Source:HGNC Symbol;Acc:11448] GO:0006781 succinyl-CoA pathwaysuccinate-CoA ligase, ADP-forming, beta subunit [Source:HGNC Symbol;Acc:11448] GO:0008152 metabolic process

succinate-CoA ligase, ADP-forming, beta subunit [Source:HGNC Symbol;Acc:11448] GO:0044281 small molecule metabolic processsuccinate-CoA ligase, ADP-forming, beta subunit [Source:HGNC Symbol;Acc:11448]succinate-CoA ligase, ADP-forming, beta subunit [Source:HGNC Symbol;Acc:11448]succinate-CoA ligase, ADP-forming, beta subunit [Source:HGNC Symbol;Acc:11448]succinate-CoA ligase, ADP-forming, beta subunit [Source:HGNC Symbol;Acc:11448]

7 GO:0006897 endocytosisGO:0016188 synaptic vesicle maturationGO:0048169 regulation of long-term neuronal synaptic plasticityGO:0048172 regulation of short-term neuronal synaptic plasticityGO:0048499 synaptic vesicle membrane organizationGO:0071310 cellular response to organic substanceGO:2000474 regulation of opioid receptor signaling pathway

1 GO:0006508 proteolysis

7 GO:0007165 signal transductiontumor necrosis factor receptor superfamily, member 8 [Source:HGNC Symbol;Acc:11923] GO:0008285 negative regulation of cell proliferationtumor necrosis factor receptor superfamily, member 8 [Source:HGNC Symbol;Acc:11923] GO:0033209 tumor necrosis factor-mediated signaling pathwaytumor necrosis factor receptor superfamily, member 8 [Source:HGNC Symbol;Acc:11923] GO:0042535 positive regulation of tumor necrosis factor biosynthetic processtumor necrosis factor receptor superfamily, member 8 [Source:HGNC Symbol;Acc:11923] GO:0043065 positive regulation of apoptotic processtumor necrosis factor receptor superfamily, member 8 [Source:HGNC Symbol;Acc:11923] GO:0045556 positive regulation of TRAIL biosynthetic processtumor necrosis factor receptor superfamily, member 8 [Source:HGNC Symbol;Acc:11923] GO:0071260 cellular response to mechanical stimulus

8 GO:0000086 G2/M transition of mitotic cell cycleGO:0000212 meiotic spindle organizationGO:0000212 meiotic spindle organizationGO:0000226 microtubule cytoskeleton organizationGO:0000278 mitotic cell cycleGO:0006184 GTP catabolic processGO:0007017 microtubule-based processGO:0051258 protein polymerization

5 GO:0006468 protein phosphorylationGO:0007243 intracellular protein kinase cascade

GO:0019221 cytokine-mediated signaling pathwayGO:0060337 type I interferon-mediated signaling pathwayGO:0060338 regulation of type I interferon-mediated signaling pathway

5 GO:0006119 oxidative phosphorylationubiquinol-cytochrome c reductase core protein II [Source:HGNC Symbol;Acc:12586] GO:0006508 proteolysisubiquinol-cytochrome c reductase core protein II [Source:HGNC Symbol;Acc:12586] GO:0009060 aerobic respirationubiquinol-cytochrome c reductase core protein II [Source:HGNC Symbol;Acc:12586] GO:0022904 respiratory electron transport chainubiquinol-cytochrome c reductase core protein II [Source:HGNC Symbol;Acc:12586] GO:0044281 small molecule metabolic processubiquinol-cytochrome c reductase core protein II [Source:HGNC Symbol;Acc:12586]ubiquinol-cytochrome c reductase core protein II [Source:HGNC Symbol;Acc:12586]ubiquinol-cytochrome c reductase core protein II [Source:HGNC Symbol;Acc:12586]

ubiquinol-cytochrome c reductase core protein II [Source:HGNC Symbol;Acc:12586]ubiquinol-cytochrome c reductase core protein II [Source:HGNC Symbol;Acc:12586]ubiquinol-cytochrome c reductase core protein II [Source:HGNC Symbol;Acc:12586]ubiquinol-cytochrome c reductase core protein II [Source:HGNC Symbol;Acc:12586]

19 GO:0006112 energy reserve metabolic processvesicle-associated membrane protein 2 (synaptobrevin 2) [Source:HGNC Symbol;Acc:12643] GO:0006461 protein complex assemblyvesicle-associated membrane protein 2 (synaptobrevin 2) [Source:HGNC Symbol;Acc:12643] GO:0006892 post-Golgi vesicle-mediated transportvesicle-associated membrane protein 2 (synaptobrevin 2) [Source:HGNC Symbol;Acc:12643] GO:0006944 cellular membrane fusionvesicle-associated membrane protein 2 (synaptobrevin 2) [Source:HGNC Symbol;Acc:12643] GO:0007268 synaptic transmissionvesicle-associated membrane protein 2 (synaptobrevin 2) [Source:HGNC Symbol;Acc:12643] GO:0007269 neurotransmitter secretionvesicle-associated membrane protein 2 (synaptobrevin 2) [Source:HGNC Symbol;Acc:12643] GO:0009749 response to glucose stimulusvesicle-associated membrane protein 2 (synaptobrevin 2) [Source:HGNC Symbol;Acc:12643] GO:0014047 glutamate secretionvesicle-associated membrane protein 2 (synaptobrevin 2) [Source:HGNC Symbol;Acc:12643] GO:0016044 cellular membrane organizationvesicle-associated membrane protein 2 (synaptobrevin 2) [Source:HGNC Symbol;Acc:12643] GO:0016079 synaptic vesicle exocytosisvesicle-associated membrane protein 2 (synaptobrevin 2) [Source:HGNC Symbol;Acc:12643] GO:0016192 vesicle-mediated transportvesicle-associated membrane protein 2 (synaptobrevin 2) [Source:HGNC Symbol;Acc:12643] GO:0017156 calcium ion-dependent exocytosisvesicle-associated membrane protein 2 (synaptobrevin 2) [Source:HGNC Symbol;Acc:12643] GO:0017157 regulation of exocytosisvesicle-associated membrane protein 2 (synaptobrevin 2) [Source:HGNC Symbol;Acc:12643] GO:0032869 cellular response to insulin stimulusvesicle-associated membrane protein 2 (synaptobrevin 2) [Source:HGNC Symbol;Acc:12643] GO:0043001 Golgi to plasma membrane protein transportvesicle-associated membrane protein 2 (synaptobrevin 2) [Source:HGNC Symbol;Acc:12643] GO:0044267 cellular protein metabolic processvesicle-associated membrane protein 2 (synaptobrevin 2) [Source:HGNC Symbol;Acc:12643] GO:0044281 small molecule metabolic processvesicle-associated membrane protein 2 (synaptobrevin 2) [Source:HGNC Symbol;Acc:12643] GO:0050796 regulation of insulin secretionvesicle-associated membrane protein 2 (synaptobrevin 2) [Source:HGNC Symbol;Acc:12643] GO:0090316 positive regulation of intracellular protein transport

9 GO:0000122 negative regulation of transcription from RNA pGO:0003149 membranous septum morphogenesisGO:0003289 atrial septum primum morphogenesisGO:0003290 atrial septum secundum morphogenesisGO:0006351 transcription, DNA-dependentGO:0009653 anatomical structure morphogenesisGO:0016568 chromatin modificationGO:0034968 histone lysine methylationGO:0060348 bone development

No of KEGG pathway KEGG ID KEGG pathways2 hsa04623 Cytosolic DNA-sensing pathway

hsa05162 Measles

negative regulation of protein kinase activity by regulation of protein phosphorylation

7 hsa01200 Carbon metabolismhsa01100 Metabolic pathwayshsa01230 Biosynthesis of amino acidshsa00051 Fructose and mannose metabolismhsa04066 HIF-1 signaling pathwayhsa00010 Glycolysis / Gluconeogenesishsa00030 Pentose phosphate pathway

2 hsa05010 Alzheimer's disease hsa04621 NOD NOD like receptor signaling pathway

regulation of epidermal growth factor-activated receptor activity

positive regulation of G2/M transition of mitotic cell cycle

ionotropic glutamate receptor signaling pathwaynucleotide-binding domain, leucine rich repeat containing receptor signaling pathway


smooth endoplasmic reticulum calcium ion homeostasis2 hsa00250 Alanine, aspartate and glutamate metabolism

hsa01100 Metabolic pathways

activation of signaling protein activity involved in unfolded protein response

endoplasmic reticulum unfolded protein response

response to follicle-stimulating hormone stimulus

11 hsa04020 Calcium signaling pathway - Homo sapiens (human)hsa04022 cGMP-PKG signaling pathway - Homo sapiens (human)hsa04024 cAMP signaling pathway - Homo sapiens (human)hsa04260 Cardiac muscle contraction - Homo sapiens (human)hsa04261 Adrenergic signaling in cardiomyocytes - Homo sapiens (human)hsa04919 Thyroid hormone signaling pathway - Homo sapiens (human)hsa04972 Pancreatic secretion - Homo sapiens (human)hsa05010 Alzheimer's disease - Homo sapiens (human)hsa05410 Hypertrophic cardiomyopathy (HCM) - Homo sapiens (human)hsa05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) - Homo sapiens (human)hsa05414 Dilated cardiomyopathy - Homo sapiens (human)

regulation of cardiac muscle cell membrane potential0 0

monoubiquitinated histone H2A deubiquitination

1 hsa04530 Tight junction - Homo sapiens (human)

negative regulation of keratinocyte proliferationpositive regulation of transcription from RNA polymerase II promoter

negative regulation of cellular response to growth factor stimulus

5 hsa04210 Apoptosis - Homo sapiens (human)hsa04622 RIG-I-like receptor signaling pathway - Homo sapiens (human)hsa04668 TNF signaling pathway - Homo sapiens (human)hsa05152 Tuberculosis - Homo sapiens (human)

positive regulation of I-kappaB kinase/NF-kappaB cascade hsa05161 Hepatitis B - Homo sapiens (human)

1 hsa04310 Wnt signaling pathway - Homo sapiens (human)

negative regulation of Wnt receptor signaling pathway

negative regulation of transcription, DNA-dependentpositive regulation of transcription, DNA-dependentpositive regulation of transcription from RNA polymerase II promoterpositive regulation of transcription from RNA polymerase III promoter

3 hsa01212 Fatty acid metabolism - Homo sapiens (human)

hsa00071 Fatty acid degradation - Homo sapiens (human)hsa03320 PPAR signaling pathway - Homo sapiens (human)

5 hsa00270 Cysteine and methionine metabolism - Homo sapiens (human)hsa01100 Metabolic pathways - Homo sapiens (human)hsa00450 Selenocompound metabolism - Homo sapiens (human)hsa01230 Biosynthesis of amino acids - Homo sapiens (human)hsa00260 Glycine, serine and threonine metabolism - Homo sapiens (human)

protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine

endoplasmic reticulum unfolded protein response

positive regulation of I-kappaB kinase/NF-kappaB cascade

positive regulation of NF-kappaB transcription factor activity

1 hsa04142 Lysosome - Homo sapiens (human)

34 hsa04370 VEGF signaling pathway - Homo sapiens (human)hsa04012 ErbB signaling pathway - Homo sapiens (human)hsa05214 Glioma - Homo sapiens (human)hsa05212 Pancreatic cancer - Homo sapiens (human)hsa05223 Non-small cell lung cancer - Homo sapiens (human)hsa05206 MicroRNAs in cancer - Homo sapiens (human)hsa05205 Proteoglycans in cancer - Homo sapiens (human)hsa05230 Central carbon metabolism in cancer - Homo sapiens (human)hsa04320 Dorso-ventral axis formation - Homo sapiens (human)hsa04010 MAPK signaling pathway - Homo sapiens (human)

transmembrane receptor protein tyrosine kinase signaling pathway hsa04060 Cytokine-cytokine receptor interaction - Homo sapiens (human)epidermal growth factor receptor signaling pathway hsa04068 FoxO signaling pathway - Homo sapiens (human)

hsa04144 Endocytosis - Homo sapiens (human)hsa04912 GnRH signaling pathway - Homo sapiens (human)hsa04915 Estrogen signaling pathway - Homo sapiens (human)hsa04921 Oxytocin signaling pathway - Homo sapiens (human)hsa05120 Epithelial cell signaling in Helicobacter pylori infection - Homo sapiens (human)

fibroblast growth factor receptor signaling pathway hsa05160 Hepatitis C - Homo sapiens (human)hsa05200 Pathways in cancer - Homo sapiens (human)hsa05219 Bladder cancer - Homo sapiens (human)hsa04014 Ras signaling pathway - Homo sapiens (human)hsa04015 Rap1 signaling pathway - Homo sapiens (human)

positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in Ghsa04020 Calcium signaling pathway - Homo sapiens (human)positive regulation of catenin import into nucleus hsa04066 HIF-1 signaling pathway - Homo sapiens (human)negative regulation of epidermal growth factor receptor signaling pathway hsa04072 Phospholipase D signaling pathway - Homo sapiens (human)

hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human)hsa04510 Focal adhesion - Homo sapiens (human)hsa04520 Adherens junction - Homo sapiens (human)

activation of phospholipase A2 activity by calcium-mediated signaling hsa04540 Gap junction - Homo sapiens (human)hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human)hsa05213 Endometrial cancer - Homo sapiens (human)hsa05215 Prostate cancer - Homo sapiens (human)

positive regulation of nitric oxide biosynthetic process hsa05218 Melanoma - Homo sapiens (human)hsa05231 Choline metabolism in cancer - Homo sapiens (human)

positive regulation of epithelial cell proliferation

positive regulation of protein kinase B signaling cascade

3 hsa00230 Purine metabolism - Homo sapiens (human)hsa00240 Pyrimidine metabolism - Homo sapiens (human)hsa05169 Epstein-Barr virus infection - Homo sapiens (human)

purine ribonucleoside diphosphate catabolic process

2 hsa01040 Biosynthesis of unsaturated fatty acids - Homo sapiens (human)hsa01212 Fatty acid metabolism - Homo sapiens (human)

1 hsa04727 GABAergic synapse - Homo sapiens (human)

Mo-molybdopterin cofactor biosynthetic processestablishment of synaptic specificity at neuromuscular junction

3 hsa01100 Metabolic pathways - Homo sapiens (human)hsa00480 Glutathione metabolism - Homo sapiens (human)hsa00270 Cysteine and methionine metabolism - Homo sapiens (human)

12 hsa01212 Fatty acid metabolism - Homo sapiens (human)hsa01100 Metabolic pathways - Homo sapiens (human)hsa00062 Fatty acid elongation - Homo sapiens (human)hsa00071 Fatty acid degradation - Homo sapiens (human)hsa01040 Biosynthesis of unsaturated fatty acids - Homo sapiens (human)

hsa00280 Valine, leucine and isoleucine degradation - Homo sapiens (human)hsa01200 Carbon metabolism - Homo sapiens (human)hsa00310 Lysine degradation - Homo sapiens (human)hsa00380 Tryptophan metabolism - Homo sapiens (human)hsa00410 beta-Alanine metabolism - Homo sapiens (human)hsa00640 Propanoate metabolism - Homo sapiens (human)hsa00650 Butanoate metabolism - Homo sapiens (human)

4 hsa04976 Bile secretion - Homo sapiens (human)hsa00900 Terpenoid backbone biosynthesis - Homo sapiens (human)hsa01100 Metabolic pathways - Homo sapiens (human)hsa04152 AMPK signaling pathway - Homo sapiens (human)

negative regulation of striated muscle cell apoptotic processpositive regulation of cardiac muscle cell apoptotic process

positive regulation of stress-activated MAPK cascade

positive regulation of skeletal muscle tissue development

positive regulation of smooth muscle cell proliferation

negative regulation of insulin secretion involved in cellular response to glucose stimulus

5 hsa00562 Inositol phosphate metabolism - Homo sapiens (human)hsa04070 Phosphatidylinositol signaling system - Homo sapiens (human)hsa04662 B cell receptor signaling pathway - Homo sapiens (human)hsa04666 Fc gamma R-mediated phagocytosis - Homo sapiens (human)hsa04910 Insulin signaling pathway - Homo sapiens (human)

negative regulation of platelet-derived growth factor receptor signaling pathwaynegative regulation of neuron projection development

negative regulation of insulin-like growth factor receptor signaling pathway

negative regulation of insulin receptor signaling pathway

0 0 0

8 hsa00010 Glycolysis / Gluconeogenesis - Homo sapiens (human)hsa00270 Cysteine and methionine metabolism - Homo sapiens (human)hsa00620 Pyruvate metabolism - Homo sapiens (human)hsa00640 Propanoate metabolism - Homo sapiens (human)hsa01100 Metabolic pathways - Homo sapiens (human)hsa04922 Glucagon signaling pathway - Homo sapiens (human)

hsa04066 HIF-1 signaling pathway - Homo sapiens (human)hsa05230 Central carbon metabolism in cancer - Homo sapiens (human)

26 hsa04150 mTOR signaling pathway - Homo sapiens (human)positive regulation of endothelial cell proliferation hsa04072 Phospholipase D signaling pathway - Homo sapiens (human)

hsa04211 Longevity regulating pathway - Homo sapiens (human)hsa04931 Insulin resistance - Homo sapiens (human)hsa04910 Insulin signaling pathway - Homo sapiens (human)hsa04920 Adipocytokine signaling pathway - Homo sapiens (human)hsa04930 Type II diabetes mellitus - Homo sapiens (human)

epidermal growth factor receptor signaling pathway hsa04213 Longevity regulating pathway - multiple species - Homo sapiens (human)hsa05214 Glioma - Homo sapiens (human)hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human)hsa04012 ErbB signaling pathway - Homo sapiens (human)

fibroblast growth factor receptor signaling pathway hsa04066 HIF-1 signaling pathway - Homo sapiens (human)hsa04152 AMPK signaling pathway - Homo sapiens (human)hsa04919 Thyroid hormone signaling pathway - Homo sapiens (human)hsa05200 Pathways in cancer - Homo sapiens (human)hsa05205 Proteoglycans in cancer - Homo sapiens (human)hsa05221 Acute myeloid leukemia - Homo sapiens (human)hsa05230 Central carbon metabolism in cancer - Homo sapiens (human)hsa05231 Choline metabolism in cancer - Homo sapiens (human)hsa04140 Regulation of autophagy - Homo sapiens (human)hsa04630 Jak-STAT signaling pathway - Homo sapiens (human)hsa05215 Prostate cancer - Homo sapiens (human)hsa04010 MAPK signaling pathway - Homo sapiens (human)

positive regulation of actin filament polymerization hsa05161 Hepatitis B - Homo sapiens (human)hsa05206 MicroRNAs in cancer - Homo sapiens (human)hsa04115 p53 signaling pathway - Homo sapiens (human)

positive regulation of transcription from RNA polymerase III promoter


negative regulation of NFAT protein import into nucleuspositive regulation of protein kinase B signaling cascade

6 hsa00190 Oxidative phosphorylation - Homo sapiens (human)hsa01100 Metabolic pathways - Homo sapiens (human)hsa04932 Non-alcoholic fatty liver disease (NAFLD) - Homo sapiens (human)hsa05010 Alzheimer's disease - Homo sapiens (human)hsa05012 Parkinson's disease - Homo sapiens (human)hsa05016 Huntington's disease - Homo sapiens (human)

regulation of mitochondrial membrane potential

6 hsa00190 Oxidative phosphorylation - Homo sapiens (human)hsa01100 Metabolic pathways - Homo sapiens (human)hsa04932 Non-alcoholic fatty liver disease (NAFLD) - Homo sapiens (human)hsa05010 Alzheimer's disease - Homo sapiens (human)hsa05012 Parkinson's disease - Homo sapiens (human)hsa05016 Huntington's disease - Homo sapiens (human)

1 hsa04080 Neuroactive ligand-receptor interaction - Homo sapiens (human)

transcription initiation from RNA polymerase II promoter

regulation of glucocorticoid biosynthetic process

2 hsa03013 RNA transport - Homo sapiens (human)hsa05164 Influenza A - Homo sapiens (human)

4 hsa01230 Biosynthesis of amino acids - Homo sapiens (human)hsa00360 Phenylalanine metabolism - Homo sapiens (human)hsa00400 Phenylalanine, tyrosine and tryptophan biosynthesis - Homo sapiens (human)hsa01100 Metabolic pathways - Homo sapiens (human)

10 hsa01230 Biosynthesis of amino acids - Homo sapiens (human)hsa01100 Metabolic pathways - Homo sapiens (human)hsa01200 Carbon metabolism - Homo sapiens (human)hsa05230 Central carbon metabolism in cancer - Homo sapiens (human)hsa00010 Glycolysis / Gluconeogenesis - Homo sapiens (human)hsa00030 Pentose phosphate pathway - Homo sapiens (human)hsa00051 Fructose and mannose metabolism - Homo sapiens (human)hsa00052 Galactose metabolism - Homo sapiens (human)hsa03018 RNA degradation - Homo sapiens (human)hsa04152 AMPK signaling pathway - Homo sapiens (human)

0 0 0

1 hsa00514 Other types of O-glycan biosynthesis - Homo sapiens

0 0 0

7 hsa04020 Calcium signaling pathway - Homo sapiens (human)hsa04062 Chemokine signaling pathway - Homo sapiens (human)hsa04072 Phospholipase D signaling pathway - Homo sapiens (human)hsa04650 Natural killer cell mediated cytotoxicity - Homo sapiens (human)hsa04670 Leukocyte transendothelial migration - Homo sapiens (human)hsa04912 GnRH signaling pathway - Homo sapiens (human)hsa05161 Hepatitis B - Homo sapiens (human)

epidermal growth factor receptor signaling pathway

positive regulation of neuron projection development

positive regulation of actin filament polymerization

regulation of inositol trisphosphate biosynthetic processtumor necrosis factor-mediated signaling pathway

positive regulation of phosphatidylinositol 3-kinase activity

negative regulation of myeloid cell differentiation

vascular endothelial growth factor receptor signaling pathway


positive regulation of nitric-oxide synthase activityregulation of release of sequestered calcium ion into cytosol

regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic processpositive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process

positive regulation of reactive oxygen species metabolic process

0 0 0

0 0 0

0 0 0

5 hsa04020 Calcium signaling pathway - Homo sapiens (human)hsa04022 cGMP-PKG signaling pathway - Homo sapiens (human)hsa05012 Parkinson's disease - Homo sapiens (human)hsa05016 Huntington's disease - Homo sapiens (human)hsa05166 HTLV-I infection - Homo sapiens (human)

2 hsa05012 Parkinson's disease - Homo sapiens (human)hsa05010 Alzheimer's disease - Homo sapiens (human)

positive regulation of neurotransmitter secretion

activation of cysteine-type endopeptidase activity involved in apoptotic process

negative regulation of platelet-derived growth factor receptor signaling pathway

negative regulation of microtubule polymerization

positive regulation of peptidyl-serine phosphorylation

mitochondrial ATP synthesis coupled electron transport

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

negative regulation of neuron apoptotic processcellular response to fibroblast growth factor stimulus

negative regulation of dopamine metabolic process

regulation of long-term neuronal synaptic plasticity

positive regulation of release of sequestered calcium ion into cytosoldopamine uptake involved in synaptic transmissionnegative regulation of dopamine uptake involved in synaptic transmission

regulation of excitatory postsynaptic membrane potential

positive regulation of inositol phosphate biosynthetic processnegative regulation of thrombin receptor signaling pathway

positive regulation of protein serine/threonine kinase activity0 0 0

4 hsa01200 Carbon metabolism - Homo sapiens (human)hsa00020 Citrate cycle (TCA cycle) - Homo sapiens (human)hsa00640 Propanoate metabolism - Homo sapiens (human)hsa01100 Metabolic pathways - Homo sapiens (human)

0 0 0

regulation of long-term neuronal synaptic plasticityregulation of short-term neuronal synaptic plasticity

0 0 0

1 hsa04060 Cytokine-cytokine receptor interaction - Homo sapiens (human)

tumor necrosis factor-mediated signaling pathwaypositive regulation of tumor necrosis factor biosynthetic process

positive regulation of TRAIL biosynthetic process

0 0 0

8 hsa04380 Osteoclast differentiation - Homo sapiens (human)hsa05160 Hepatitis C - Homo sapiens (human)

hsa05162 Measles - Homo sapiens (human)hsa05164 Influenza A - Homo sapiens (human)

regulation of type I interferon-mediated signaling pathway hsa05168 Herpes simplex infection - Homo sapiens (human)hsa04630 Jak-STAT signaling pathway - Homo sapiens (human)hsa05145 Toxoplasmosis - Homo sapiens (human)hsa05169 Epstein-Barr virus infection - Homo sapiens (human)

7 hsa01100 Metabolic pathways - Homo sapiens (human)hsa00190 Oxidative phosphorylation - Homo sapiens (human)hsa04260 Cardiac muscle contraction - Homo sapiens (human)hsa04932 Non-alcoholic fatty liver disease (NAFLD) - Homo sapiens (human)hsa05010 Alzheimer's disease - Homo sapiens (human)hsa05012 Parkinson's disease - Homo sapiens (human)hsa05016 Huntington's disease - Homo sapiens (human)

5 hsa04721 Synaptic vesicle cycle - Homo sapiens (human)hsa04911 Insulin secretion - Homo sapiens (human)hsa04962 Vasopressin-regulated water reabsorption - Homo sapiens (human)hsa04130 SNARE interactions in vesicular transport - Homo sapiens (human)hsa04970 Salivary secretion - Homo sapiens (human)

positive regulation of intracellular protein transport2 hsa00310 Lysine degradation - Homo sapiens (human)

hsa05202 Transcriptional misregulation in cancer - Homo sapiens (human)

Cytosolic DNA-sensing pathway

Biosynthesis of amino acidsFructose and mannose metabolism

Glycolysis / GluconeogenesisPentose phosphate pathway

NOD like receptor signaling pathway

Calcium signaling pathway - Homo sapiens (human)cGMP-PKG signaling pathway - Homo sapiens (human)cAMP signaling pathway - Homo sapiens (human)Cardiac muscle contraction - Homo sapiens (human)Adrenergic signaling in cardiomyocytes - Homo sapiens (human)Thyroid hormone signaling pathway - Homo sapiens (human)Pancreatic secretion - Homo sapiens (human)Alzheimer's disease - Homo sapiens (human)Hypertrophic cardiomyopathy (HCM) - Homo sapiens (human)Arrhythmogenic right ventricular cardiomyopathy (ARVC) - Homo sapiens (human)Dilated cardiomyopathy - Homo sapiens (human)

Tight junction - Homo sapiens (human)

Apoptosis - Homo sapiens (human)RIG-I-like receptor signaling pathway - Homo sapiens (human)TNF signaling pathway - Homo sapiens (human)Tuberculosis - Homo sapiens (human)Hepatitis B - Homo sapiens (human)

Wnt signaling pathway - Homo sapiens (human)

Fatty acid metabolism - Homo sapiens (human)

Fatty acid degradation - Homo sapiens (human)PPAR signaling pathway - Homo sapiens (human)

Cysteine and methionine metabolism - Homo sapiens (human)Metabolic pathways - Homo sapiens (human)Selenocompound metabolism - Homo sapiens (human)Biosynthesis of amino acids - Homo sapiens (human)Glycine, serine and threonine metabolism - Homo sapiens (human)

Lysosome - Homo sapiens (human)

VEGF signaling pathway - Homo sapiens (human)ErbB signaling pathway - Homo sapiens (human)Glioma - Homo sapiens (human)Pancreatic cancer - Homo sapiens (human)Non-small cell lung cancer - Homo sapiens (human)MicroRNAs in cancer - Homo sapiens (human)Proteoglycans in cancer - Homo sapiens (human)Central carbon metabolism in cancer - Homo sapiens (human)Dorso-ventral axis formation - Homo sapiens (human)MAPK signaling pathway - Homo sapiens (human)Cytokine-cytokine receptor interaction - Homo sapiens (human)FoxO signaling pathway - Homo sapiens (human)Endocytosis - Homo sapiens (human)GnRH signaling pathway - Homo sapiens (human)Estrogen signaling pathway - Homo sapiens (human)Oxytocin signaling pathway - Homo sapiens (human)Epithelial cell signaling in Helicobacter pylori infection - Homo sapiens (human)Hepatitis C - Homo sapiens (human)Pathways in cancer - Homo sapiens (human)Bladder cancer - Homo sapiens (human)Ras signaling pathway - Homo sapiens (human)Rap1 signaling pathway - Homo sapiens (human)Calcium signaling pathway - Homo sapiens (human)HIF-1 signaling pathway - Homo sapiens (human)Phospholipase D signaling pathway - Homo sapiens (human)

PI3K-Akt signaling pathway - Homo sapiens (human)Focal adhesion - Homo sapiens (human)Adherens junction - Homo sapiens (human)Gap junction - Homo sapiens (human)Regulation of actin cytoskeleton - Homo sapiens (human)Endometrial cancer - Homo sapiens (human)Prostate cancer - Homo sapiens (human)Melanoma - Homo sapiens (human)Choline metabolism in cancer - Homo sapiens (human)

Purine metabolism - Homo sapiens (human)Pyrimidine metabolism - Homo sapiens (human)Epstein-Barr virus infection - Homo sapiens (human)

Biosynthesis of unsaturated fatty acids - Homo sapiens (human)Fatty acid metabolism - Homo sapiens (human)

GABAergic synapse - Homo sapiens (human)

Metabolic pathways - Homo sapiens (human)Glutathione metabolism - Homo sapiens (human)Cysteine and methionine metabolism - Homo sapiens (human)

Fatty acid metabolism - Homo sapiens (human)Metabolic pathways - Homo sapiens (human)Fatty acid elongation - Homo sapiens (human)Fatty acid degradation - Homo sapiens (human)Biosynthesis of unsaturated fatty acids - Homo sapiens (human)

Valine, leucine and isoleucine degradation - Homo sapiens (human)Carbon metabolism - Homo sapiens (human)Lysine degradation - Homo sapiens (human)Tryptophan metabolism - Homo sapiens (human)beta-Alanine metabolism - Homo sapiens (human)Propanoate metabolism - Homo sapiens (human)Butanoate metabolism - Homo sapiens (human)

Bile secretion - Homo sapiens (human)Terpenoid backbone biosynthesis - Homo sapiens (human)Metabolic pathways - Homo sapiens (human)AMPK signaling pathway - Homo sapiens (human)

Inositol phosphate metabolism - Homo sapiens (human)Phosphatidylinositol signaling system - Homo sapiens (human)B cell receptor signaling pathway - Homo sapiens (human)Fc gamma R-mediated phagocytosis - Homo sapiens (human)Insulin signaling pathway - Homo sapiens (human)

Glycolysis / Gluconeogenesis - Homo sapiens (human)Cysteine and methionine metabolism - Homo sapiens (human)Pyruvate metabolism - Homo sapiens (human)Propanoate metabolism - Homo sapiens (human)Metabolic pathways - Homo sapiens (human)Glucagon signaling pathway - Homo sapiens (human)

HIF-1 signaling pathway - Homo sapiens (human)Central carbon metabolism in cancer - Homo sapiens (human)

mTOR signaling pathway - Homo sapiens (human)Phospholipase D signaling pathway - Homo sapiens (human)Longevity regulating pathway - Homo sapiens (human)Insulin resistance - Homo sapiens (human)Insulin signaling pathway - Homo sapiens (human)Adipocytokine signaling pathway - Homo sapiens (human)Type II diabetes mellitus - Homo sapiens (human)Longevity regulating pathway - multiple species - Homo sapiens (human)Glioma - Homo sapiens (human)PI3K-Akt signaling pathway - Homo sapiens (human)ErbB signaling pathway - Homo sapiens (human)HIF-1 signaling pathway - Homo sapiens (human)AMPK signaling pathway - Homo sapiens (human)Thyroid hormone signaling pathway - Homo sapiens (human)Pathways in cancer - Homo sapiens (human)Proteoglycans in cancer - Homo sapiens (human)Acute myeloid leukemia - Homo sapiens (human)Central carbon metabolism in cancer - Homo sapiens (human)Choline metabolism in cancer - Homo sapiens (human)Regulation of autophagy - Homo sapiens (human)Jak-STAT signaling pathway - Homo sapiens (human)Prostate cancer - Homo sapiens (human)MAPK signaling pathway - Homo sapiens (human)Hepatitis B - Homo sapiens (human)MicroRNAs in cancer - Homo sapiens (human)p53 signaling pathway - Homo sapiens (human)

Oxidative phosphorylation - Homo sapiens (human)Metabolic pathways - Homo sapiens (human)Non-alcoholic fatty liver disease (NAFLD) - Homo sapiens (human)Alzheimer's disease - Homo sapiens (human)Parkinson's disease - Homo sapiens (human)Huntington's disease - Homo sapiens (human)

Oxidative phosphorylation - Homo sapiens (human)Metabolic pathways - Homo sapiens (human)Non-alcoholic fatty liver disease (NAFLD) - Homo sapiens (human)Alzheimer's disease - Homo sapiens (human)Parkinson's disease - Homo sapiens (human)Huntington's disease - Homo sapiens (human)

Neuroactive ligand-receptor interaction - Homo sapiens (human)

RNA transport - Homo sapiens (human)Influenza A - Homo sapiens (human)

Biosynthesis of amino acids - Homo sapiens (human)Phenylalanine metabolism - Homo sapiens (human)Phenylalanine, tyrosine and tryptophan biosynthesis - Homo sapiens (human)Metabolic pathways - Homo sapiens (human)

Biosynthesis of amino acids - Homo sapiens (human)Metabolic pathways - Homo sapiens (human)Carbon metabolism - Homo sapiens (human)Central carbon metabolism in cancer - Homo sapiens (human)Glycolysis / Gluconeogenesis - Homo sapiens (human)Pentose phosphate pathway - Homo sapiens (human)Fructose and mannose metabolism - Homo sapiens (human)Galactose metabolism - Homo sapiens (human)RNA degradation - Homo sapiens (human)AMPK signaling pathway - Homo sapiens (human)

hsa00514 Other types of O-glycan biosynthesis - Homo sapiens

Calcium signaling pathway - Homo sapiens (human)Chemokine signaling pathway - Homo sapiens (human)Phospholipase D signaling pathway - Homo sapiens (human)Natural killer cell mediated cytotoxicity - Homo sapiens (human)Leukocyte transendothelial migration - Homo sapiens (human)GnRH signaling pathway - Homo sapiens (human)Hepatitis B - Homo sapiens (human)

Calcium signaling pathway - Homo sapiens (human)cGMP-PKG signaling pathway - Homo sapiens (human)Parkinson's disease - Homo sapiens (human)Huntington's disease - Homo sapiens (human)HTLV-I infection - Homo sapiens (human)

Parkinson's disease - Homo sapiens (human)Alzheimer's disease - Homo sapiens (human)

Carbon metabolism - Homo sapiens (human)Citrate cycle (TCA cycle) - Homo sapiens (human)Propanoate metabolism - Homo sapiens (human)Metabolic pathways - Homo sapiens (human)

hsa04060 Cytokine-cytokine receptor interaction - Homo sapiens (human)

Osteoclast differentiation - Homo sapiens (human)Hepatitis C - Homo sapiens (human)

Measles - Homo sapiens (human)Influenza A - Homo sapiens (human)Herpes simplex infection - Homo sapiens (human)Jak-STAT signaling pathway - Homo sapiens (human)Toxoplasmosis - Homo sapiens (human)Epstein-Barr virus infection - Homo sapiens (human)

Metabolic pathways - Homo sapiens (human)Oxidative phosphorylation - Homo sapiens (human)Cardiac muscle contraction - Homo sapiens (human)Non-alcoholic fatty liver disease (NAFLD) - Homo sapiens (human)Alzheimer's disease - Homo sapiens (human)Parkinson's disease - Homo sapiens (human)Huntington's disease - Homo sapiens (human)

Synaptic vesicle cycle - Homo sapiens (human)Insulin secretion - Homo sapiens (human)Vasopressin-regulated water reabsorption - Homo sapiens (human)SNARE interactions in vesicular transport - Homo sapiens (human)Salivary secretion - Homo sapiens (human)

Lysine degradation - Homo sapiens (human)Transcriptional misregulation in cancer - Homo sapiens (human)

SNRPD2

SNX1 SNX2 SNX4 SNX6 SOCS1 SOCS3 SORBS2 SOS1 SOS2

SPARCL1 SPCS2 SPRY2 SRC STAT1 STAT3 STAT5A STAT5B STIP1

STUB1 TGFA TJP1 TMCO3 TNK2 TPI1 TPM1 UBASH3A UBASH3B

UBC UBE2V2 UCHL1 UROD USP8 VAPA VAV1 VAV2 VAV3

WAS YWHAZ ZFYVE28

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