absorption

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 Of}JonIZec} CfOJsef. AciD ==- AH ~ A s E = 13 ~ . A C ds a1:8:tt:ed fJJ L1 J J J Iornach  rodC'S txe LlJn. U d ~ -  Ik:Jd Ofll K. 1J1,U 9 -  IaJes . aI taIJVltle Ci q mac/Irq 00IJl. pH ? i oT fJI/lC. 1H_ 1bc.N:> fly t1lmmation If Cl CONFINEr > -rt tfCI I @ EtlMINltTIrJ f J N Q I ~ . D Ii£cE o OlufesJS £) DIOf E T CS = l VOl @ :> UIZlNG pH _ J alkaline - Sollc,(la f lS ' D  u ~ n S - phenoba.rbdO(le - ~ h C l d ~ S 1t ; c / hAt/M "c  . h .-· a 1 - ampJ1eta n JlflC O l vltC lh _ f e n P t ) ( a m ~ - pherntcllch n H ~ A-tH+ 8Ht ' : -t I-f-t I.

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  • Of}JonIZec} CfOJsef.) AciD ==- AH ! ~AsE = 13 ~ '. ACIds a1:8:tt:ed fJJ!L1 J1J J Iornach , rodC'S txe LlJn. U!d ~

    -( Ik:Jd Ofll'K. 1J1,U 9 -/::IaJes . aI/taIJ Vltle ~. Ci11q mac/Irq 00IJl. pH -? iD HoT fJI/lC." 1H_1bc.N:>

    fly t1lmmation If Cl> CONFINEr:> -rt) tfCI: I @ EtlMINltTIrJ fJNQI~.D IicE.o OlufesJS () DIOfET/CS = l' VOl. .

    @ !:> UIZlNG pH _ .J

    alkaline - Sollc,(laflS '"" D( u~n,S - phenoba.rbdO(le

    - ~hCld~S /1t;c/ hAt/M"c).h.-

    a .... 1 - ampJ1etanJlflC OlvltC-lh _ fenP't)(am'~

    - pherntcllchn

    AH~ A-tH+ 8Ht ~':& -t I-f-t

    I.

  • aCId diuresIS ~

    \.... ~ /.' ~ oq"/.

    at SC()mt/hr In tI!J'Ifb1(L SlXJm{ S /. dexl. ~ .5tJCYttJI5Y. dexlrose ~.st:t:H1 0 '1'1.,J,III1t,

    + ;'59 NH4C'

    ~--------------~-------~ In /(/jlP1a tU /()()()htt/fr.

    -11-ATP

    auncr ~fb

  • O~AL ADttlNI1TltATION

    . ~ ~ onl'f absotbed IN ~O(..o1l0N - . ',F,m DllSQlt)T'ON .. AmoqilC1 depniJ 0r1 LIPID PENfTtOmON

    - ( ftfY~'COCH~'CAI. - IONIZATION

    MO(CUlAC Nt. l.,,,,, Joc.uS't..TY also - Mexosal atal

    2.

    - A~cemph.flnq -anhchohnCIBLC/.),anhhurarvuYlfb I rCA I op,o.ds. - ~ ~ hQ6C.CQIY~ - LEVOOOPA - aO (lJtfV

    . - FweQ)eACI L - Ptfl"'lChlU a::rf\otV' .

  • (d}(n tAl kl'r) a fxJU, jlrot fZlJS mdab. In uWY Im{Dtlln6 t"ONcepr IS; HtPAr" Exr~ ~A110 - (1/ thIS IS hf11 1Pa /dlIS 1t!IrJ()'A%/

    (J C/t:erana /Imlltd I:xt f3tcJolJ rJW (txJt efYllttne.S )

    . : bhrrr Id ~ - ACJeta~e '* AlbPAANGUSl.

  • E)(~/iLT'()N f!InIO - Meavc Of aff}anc # temOvaJ of dtUB bet an CYfPt> .

    E~ = c: i-Co Ct (J tnf'tJ,ns '0 , 1 lecav, "e. -lliE!'~!! ~ Propranoldl

    -" J.

    ~ s(Jnlficant 1Jl; pa metab. I

    rakrf eILmlJ?at". dtp. on t!J Seal ftCiA) (!J Hepahc f/;nc;,o.. eN!. &:n.rl hie 10 ~Zl(~

    InhlixhrM /lndvdrJA. .

    3,

  • Rale ~ a/:J.sorpban - dekrrmnes /N1EAASIlY I meATltJN t . depends Jln - SJi.os. (,,1 Tv

    _ -=-_ l1SSUE. eEgjiffl6lUCY - dcp. On ION/ZImON - dep.JJt'l pH - SA - B~ SlJFPiV

    aslnbotn1 -depends J)Q - LJPIO &oBluTY - - pkC\ . + Bod"l fluid -pH . \' CtfAM~

    - R?oTf'IN BINDING- 'P' ~ ~ 10 + - REaloNJt((.. StOOD F{JJ(,I.) Voc..ut1 f - speCifICS ~ 1-)" tn"l(&td. I! '~Tr'.T'''''f

  • Al:wrpl7on - R~ lona/JlIocd PIoIN } rxJl {)J)(lU" plc" / pfld((.Zntkitf.' IH := faJfeJ- ~ fJAraha7 tIhoclo-

    TOPiCAL

    Main barflU == -SmAT()M CO~NEf)/t1 SIr:ps (J) Hl61J MW / @ Low UPlO c!oLIJ8IuTy

    -

    /,6 thllJ' GTN also ~1J61t'JO'~ HYOSCINE. EfHINY lOEsmttf)1OL. PlN611t'1471G1!l FN~. F~N1"AItYL NI roT/Hi .

  • IY Rapid I~ndable Ira tan I druBs - avou:iJ hSSte compJlcolxrls

    IN'Ac/frfICN f(apld hie SA

    JI1f tY_D!PrB1fD\L Oqxncb On Sflt:. .

    :>10;4,., _j IOT :l- IO)JM--tfsftolJCH!OIS 21''''' ~ U N.,veOl-1