ac marine collagen pf - active concepts · ac marine collagen pf protocol • ac marine collagen pf...
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![Page 1: AC Marine Collagen PF - Active Concepts · AC Marine Collagen PF Protocol • AC Marine Collagen PF is capable of increasing stratum corneum moisturization values after 1 hour •](https://reader035.vdocument.in/reader035/viewer/2022062604/5fb8c6f8481bfb02933edfa9/html5/thumbnails/1.jpg)
AC Marine Collagen PF
Tomorrow’s Vision… Today!®
Hydration + Conditioning
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Technical Information:
Product Code: 20739
INCI Name: Soluble Collagen
INCI Status: Conforms
Suggested Use Levels: 1.0 – 10.0%
Suggested Applications: Hydration, Conditioning
AC Marine Collagen PF
![Page 3: AC Marine Collagen PF - Active Concepts · AC Marine Collagen PF Protocol • AC Marine Collagen PF is capable of increasing stratum corneum moisturization values after 1 hour •](https://reader035.vdocument.in/reader035/viewer/2022062604/5fb8c6f8481bfb02933edfa9/html5/thumbnails/3.jpg)
• Collagen has become the topic of daily conversation!• Improving the skin and lips natural collagen structure • Introducing new collagen through invasive injections
• AC Marine Collagen PF consists of:• Fish derived soluble collagen • Excellent hydrating properties • Film forming benefits in a safe, reliable manner
AC Marine Collagen PF
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Science
• Collagen is created by fibroblasts, specialized cells found in the dermal layer of the skin
• Fibroblasts are responsible for the production of collagen, elastin, and fibronectin that act as the structural support beams within the skin
• Fibroblasts synthesize collagen within the cell and release it through exocytosis• A process by which molecules diffuse through the cell membrane
• Once outside the cell, the collagen molecules will self-assemble, creating the same structures found in skin
AC Marine Collagen PF
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Benefits
• Restore one’s youthful appearance by hydrating the skin and helping to increase its natural collagen production
• Can be easily incorporated into the water phase
• Can be used in a wide variety of personal care formulas
• Marine collagen is capitalizing on what is arguably the most profound trend in cosmetics in the last decade
AC Marine Collagen PF
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Improvements in Hydration
AC Marine Collagen PF
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12
Baseline AC Marine Collagen PF
Pe
rce
nt
(%)
Imp
rove
me
nt
Protocol• 2 week study with 10 M/F
• Concentration: 5.0%
• Applied on volar forearms twice daily
• Improved skin hydration by 12%
• Enhance hydration levels for both skin and scalp care
Figure 1. Percent improvement in hydration following application of AC Marine Collagen PF.
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Moisturization Assay
AC Marine Collagen PF
Protocol
• AC Marine Collagen PF is capable of increasing stratum corneum moisturization values after 1 hour
• AC Marine Collagen PF may be added to anhydrous systems to effectively increase epidermal moisture
0
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10 20 30 40 50 60 70 80 90 100
Pe
rce
nt
(%)
Mo
istu
re U
pta
ke
AC Marine Collagen PBF
Hydrolyzed Collagen
Figure 2. Percent increase in moisturization following application of AC Marine Collagen PF.
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Improvements in Compatability
AC Marine Collagen PF
Protocol• Concentration: 5.0%
• Increased the sensorial perception of wet combing ease by 90.0%
• Participants rated the control as increasing combability by 40.0% and the test material as increasing dry combability by 50.0%
• Useful for preventing damage and breakage which typically results from excessive combing forces during styling
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Wet Combability Dry Combability
Pe
rce
nt
(%)
Imp
rove
me
nt
Control AC Marine Collagen PF
Figure 3. Percent change in Combability.
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ORAC Assay
AC Marine Collagen PF
Protocol• AC Marine Collagen PF exhibited
antioxidant activity comparable to 100μM Trolox®
• AC Marine Collagen PF increased as the concentration increased, as a result we can assure that its ability to minimize oxidative stress is dose dependent
• Ingredient is not only capable of providing functional benefits but it is also capable of providing potent antioxidant benefits when added to cosmetic applications
0
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100µM Trolox 12.5µM Trolox 0.5% AC MarineCollagen PF
0.1% AC MarineCollagen PF
0.05% AC MarineCollagen PF
An
tio
xid
ant
Cap
acit
y (µ
MTE
)
Figure 4. Antioxidant capacities.
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Sirius Red Fast Green Report
AC Marine Collagen PF
Protocol• Human dermal fibroblasts were seeded
into 24-well tissue culture plates
• AA2G and IGF-1 were used a positive controls
• Concentrations: 1.0%, 0.1%, 0.01%
• AC Marine Collagen PF exhibited positive collagen synthesis activity
• The increase in collagen production may lead to improvement in the dermal-epidermal junction integrity as well as an improved scaffolding matrix
2.0
0
2.3
1
1.3
0 1.8
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1.8
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50
.91
61
.37
26
.05 45
.98
46
.13
46
.32
1
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100µg/mL 50ng/mL 1% 0.1% 0.01%
Ascorbic Acid IGF-1 CompleteMedia
20739 AC Marine Collagen PF
Pro
tein
Co
nce
ntr
atio
n (
µg)
Collagen Proteins Non-Collagen Proteins
Figure 5. Collagen and non-collagen protein concentrations.
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Sirius Red Fast Green Report
AC Marine Collagen PF
Figure 6. Percent collagen compared to non-collagen proteins.
3.92% 3.76%
4.99%3.99% 4.08% 3.84%
0%
5%
10%
15%
20%
100µg/mL 50ng/mL 1% 0.1% 0.01%
Ascorbic Acid IGF-1 CompleteMedia
20739 AC Marine Collagen PF
% C
olla
gen
/No
n-C
olla
gen
Pro
tein
s
Protocol• Human dermal fibroblasts were seeded
into 24-well tissue culture plates
• AA2G and IGF-1 were used as positive controls
• Concentrations: 1.0%, 0.1%, 0.01%
• AC Marine Collagen PF exhibited positive collagen synthesis activity
• The increase in collagen production may lead to improvement in the dermal-epidermal junction integrity as well as an improved scaffolding matrix
![Page 12: AC Marine Collagen PF - Active Concepts · AC Marine Collagen PF Protocol • AC Marine Collagen PF is capable of increasing stratum corneum moisturization values after 1 hour •](https://reader035.vdocument.in/reader035/viewer/2022062604/5fb8c6f8481bfb02933edfa9/html5/thumbnails/12.jpg)
Technical Information:
Product Code: 20739
INCI Name: Soluble Collagen
INCI Status: Conforms
Suggested Use Levels: 1.0 – 10.0%
Suggested Applications: Hydration, Conditioning
AC Marine Collagen PF
![Page 13: AC Marine Collagen PF - Active Concepts · AC Marine Collagen PF Protocol • AC Marine Collagen PF is capable of increasing stratum corneum moisturization values after 1 hour •](https://reader035.vdocument.in/reader035/viewer/2022062604/5fb8c6f8481bfb02933edfa9/html5/thumbnails/13.jpg)
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AC Marine Collagen PF