acupuncture sara bowling may2016 pci conference

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ACUPUNCTURE IN PALLIATIVE CARE EVIDENCE BASED MEDICINE Sara Bowling, MD Family Medicine and Medical Acupuncture Family Care Network

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Page 1: Acupuncture sara bowling may2016 pci conference

ACUPUNCTURE IN PALLIATIVE CARE

EVIDENCE BASED MEDICINE

Sara Bowling, MDFamily Medicine and Medical AcupunctureFamily Care Network

Page 2: Acupuncture sara bowling may2016 pci conference

INTEGRATIVE MEDICINE

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CONVENTIONAL CARE

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Symptom A

Symptom D

Symptom C

Symptom B

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THE PILL BURDENAverage elderly patient is on 8-13 medications

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Anorexia

Anxiety

Constipation

Delirium

Depression

Diarrhea

SYMPTOMS IN END OF LIFEDyspnea

Fatigue

Nausea and Vomiting

Pain

Respiratory tract secretions

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Dexamethasone

Diazepam and Lorazepam

Docusate and Senna

Haloperidol

Amitriptyline and Fluoxetine

WORLD HEALTH ORGANIZATION ESSENTIAL MEDICATIONS LIST FOR PALLIATIVE CARE

Loperamide

Morphine

Metoclopramide

Ibuprofen

Hyoscine butyl-bromide

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Dexamethasone - A

Diazepam/ Lorazepam- D

Docusate and Senna-D

Haloperidol - A

Amitriptyline and Fluoxetine

EVIDENCE BEHIND MEDICATIONS

Loperamide - D

Morphine - A

Metoclopramide

Ibuprofen

Hyoscine butyl-bromide

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SIDE EFFECTS

Dexamethasone

Anaphylactic reactions, acute myopathy, perineal irritation, psychiatric disturbances

HaloperidolQT prolongation, anticholinergic effects, leukopenia, CNS depression, extrapyramidal symptoms, esophageal dysmotility, orthostatic hypotension

Morphine

Constipation, CNS depression, hypotension, hypersensitivity reaction, respiratory depression

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ACUPUNCTURESAFE & EFFECTIVE

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ACUPUNCTURE IS SAFE

Rare Adverse Events

Dizziness

Subcutaneous bleeding

Mild burn

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ACUPUNCTURE IS SAFESpecial Considerations

Never placed in tumor or ulcerated area

Never placed in limbs prone to lymphedema

Care when treating over chest wall in cachectic patients

No electroacupuncture if pacemaker

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IS ACUPUNCTURE PAINFUL?

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WHAT IS ACUPUNCTURE?

Originated 2000 years ago

North America in the 1970s as useful for anesthesia

A series of meridians through which energy flows

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THE SCIENCE OF ACUPUNCTURE?

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PAIN MODULATION

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ENDOGENOUS OPIOIDS

Stimulates release of dynorphin, enkephalin, beta-endorphin.

Increases endogenous cannabinoid receptors

Up-regulates opioids in inflamed tissues

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ENDOGENOUS OPIOIDSOpioid antagonists such as naloxone, can reverse the analgesic

effects of acupuncture.

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NATIONAL INSTITUTE OF HEALTH CONSENSUS STATEMENT, 1997

“Acupuncture is an effective treatment modality for adult postoperative and chemotherapy nausea and vomiting.”

“There is sufficient evidence of acupuncture’s value to expand its use into conventional medicine and encourage

further studies of its physiology and clinical value”

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ACUPUNCTURE ISEVIDENCE BASED MEDICINE

Research / DataClinical Expertise

Patient Values & Expectations

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The challenges of the acupuncture control: SHAM acupuncture

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SYSTEMATIC REVIEWSFatigue*

Nausea-Vomiting**

Pain*

Hot flashes*

Xerostomia

Dyspnea

Anxiety

Anorexia

Constipation

Paresthesia

Insomnia

Limb edema

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WHO’S 3- STEP LADDER FOR CANCER PAIN RELIEF

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PAIN

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PAIN

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NAUSE AND VOMITING

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FATIGUE

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HOT FLASHES

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INTEGRATIVE EVIDENCE BASED MEDICINE

Research / DataClinical Expertise

Patient Values & Expectations

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Acupuncture is effective forPain control

Nausea and vomitingFatigue

Hot flashes

It is best used alongside conventional medicine early on in treatment, rather than as last resort

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Alimi D, Rubino C, Pichard-Leandri E. et al. Analgesic Effect of Auricular Acupuncture for Cancer Pain: A Rondomized, Blinded, Controlled Trial. J Clin Oncol. 2003; 21: 4120-6

Bardia A, Barton DL, Prokop LJ et al. Efficacy of complementary and alternative medicine therapies in relieving cancer pain: a systematic review. J Clin Oncol 2006; 24: 5457-5464

Langevin H, Yandow J. Relationship of Acupuncture Points and Meridians to Connective Tissue Plans. The Anatomical Record 2002: 269: 257-265.

Lau C, Wu X, Chung V. et al. Acupuncture and Related Therapies for Symptom Management in Palliative Cancer Care: Systematic Review and Meta-analysis. 2016: 95: 2901

Lee H, Schmidt K, Ernst E. Acupuncture for the relief of cancer-related pain: a systematic review. Eur J Pain 2005; 9: 437-444.

Lesi G, Razzini G, Musti M, et al. Acupuncture As an Integrative Approach for the Treatment of Hot Flashes in Women with Breast Cancer: A prospective Multicenter Randomized Control Trial. Journal of Clin Oncology 2016; 2893.

Mao JJ, Xie SX, Farrar JT, et.al. A Randomised trial of electro-acupuncture for arthralgia related to amromitase inhibitor use. Euro J Cancer. 2014; 50: 267-76

McCarthy L, Dolovich L, Haq M. et al. Frequency of risk factors that potentially increase harm from medications in older adults receiving primary care. Can J Clin Pharmacol. 2007:14; 283-90

Mehling WE, Jacobs B, Acree M, et. al. Symptom Management with massage and acupuncture in postoperative cancer patietns: a randomized controlled trial. J Pain Symptom Manage. 2007; 33: 258-66

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Molassiotis A, Bardy J, Finnegan-John J, et. al. Acupuncture for cancer-related fatigue in patients with breast cancer: a pragmatic randomized controlled trial. J Clin Oncol. 2012; 30: 4470-6.

Quin MX, Xi CY, Zhou H. Observation on effect of acupoint injection for treatment of morphine induced constipation. J Qiqihar Med Coll. 2010: 31:3921.

Rostock M, Jaroslawski K, Guethlin C. Chemotherapy induced, peripheral neuropathy in cancer patients: a four arm randomized trial on the effectiveness of acupuncture. Evid Based Complement Alternat Med. 2013; 349653.

Shen J, Wegner N, Glaspy J. et al. Electroacupuncutre for control of myeloablative chemotherapy-induced emesis: a randomized controlled tiral. JAMA 2000; 284: 2755-61

Smith C, Carmady B, Thornton C, et al. The effect of acupuncture on post-cancer fatigue and well-being for women recovering from breast cancer: a pilot randomized controlled tiral. Acupunct Med. 2013;31:9-15.

Tang WR, Chen WJ, Yu CT, et al. Effects of acupressure on fatigue of lung cancer patients undergoing chemotherapy: an experimental pilot study. Complement Ther Med. 2014; 22: 581-591

Tao W, JIang H, Tao X. et al. Effects of Acupuncture, Tuina, Tai Chi, Qigong, and Traditional Chinese Medicine Five-Element Music Therapy on Symptom Management and Quality of Life for Cancer Patients: A Meta-analysis. J Pain Symptom Manage. 2016 51; 728-47

Towler P, Molassiotis A, Brearley SG. What is the evidence for use of acupuncture as an intervention for symptom management in cancer supportive and palliative care: an integrative overview of reviews. Support Care Cancer 2013: 21:2913-2923

Zeng Y, Luo T, Finnegan-John J, et al. Meta-analysis of randomized controlled trials of acupuncture for cancer-related fatigue. Integr Cancer Ther 2013; 13: 193-200