Adult Immunization 2010

MMR Vaccine Segment

This material is in the public domainThis information is valid as of May 25, 2010

Measles-Mumps-RubellaVaccine (MMR)

• Contains live attenuated viruses• 1-dose efficacy varies from 80%

(mumps) to 95% (measles and rubella)

• Duration of immunity probably lifelong

• Schedule is 2 doses• All adults born in 1957 or later should

have documentation of at least 1 dose (or other evidence of immunity)

Adults at High Risk forMeasles

• College students

• International travelers

• Healthcare personnel

MMR VaccineContraindications

• Severe allergic reaction to vaccine component or following prior dose

• Pregnancy

• Immunosuppression

Measles Vaccine and HIV Infection

• MMR recommended for persons with asymptomatic and minimally symptomatic HIV infection

• NOT recommended for persons with evidence of severe immuno-suppression

• Prevaccination HIV testing of an otherwise healthy person not recommended

MMR Vaccination of Women of Childbearing Age

• Ask if pregnant or likely to become so in next 4 weeks

• Exclude those who say "yes“

• For others

– explain theoretical risks

– vaccinate

MMR VaccinePrecautions

• Moderate or severe acute illness

• Recent receipt of a blood product

• History of thrombocytopenia or thrombycytopenic purpura

MMR Adverse Reactions

Fever 5%-15%

Rash 5%

Joint symptoms 25%

Thrombocytopenia <1/30,000 doses

Parotitis rare

Deafness rare

Encephalopathy <1/1,000,000 doses

National Center for Immunization and Respiratory Diseases

Contact Information

• Telephone (800) CDC-INFO

• Email nipinfo@cdc.gov

• Website http://www.cdc.gov/vaccines/

• Broadcast Updates and Resources

Web Page

http://www.cdc.gov/vaccines/ed/webcasts.htm