access to novel imidazo[1,5-a]pyrazine scaffolds by the ... · ‡dipartimento di scienze...

Post on 23-Sep-2020

2 Views

Category:

Documents

0 Downloads

Preview:

Click to see full reader

TRANSCRIPT

1

Access to Novel Imidazo[1,5-a]pyrazine Scaffolds by the Combined Use of a Three-Component Reaction and a Base-

Assisted Intramolecular Cyclization

Orazio A. Attanasi,‡ Gianfranco Favi,*‡ Gianluca Giorgi,† Roberta Majer,‡ Francesca Romana Perrulli*‡ and Stefania Santeusanio‡

‡Dipartimento di Scienze Biomolecolari, Sezione COSON, Università degli Studi di Urbino “Carlo Bo”, Via I Maggetti 24, 61029 Urbino, Italy and †Dipartimento di Chimica, Università degli Studi

di Siena, Via Aldo Moro, 53100 Siena, Italy

e-mail: gianfranco.favi@uniurb.it

SUPPORTING INFORMATION

1. Copies of 1H and 13C NMR spectra of products S2-S25

Electronic Supplementary Material (ESI) for Organic & Biomolecular Chemistry.This journal is © The Royal Society of Chemistry 2014

2

1. 1H and 13C NMR spectra of products.

3

4

5

6

7

8

9

10

11

12

13

14

15

16

17

18

NN

N

OS

O

HN

O

O

O2N

19

20

5bd

2

21

NN

N

OS

O

HN

O

O

22

23

NN

N

OS

O

HN

5bg

O

O

Cl

24

25

top related