compact cancer killers simulating next-generation laser...

Compact Cancer Killers ─

Simulating Next-Generation Laser-Driven Ion Accelerators

Michael Bussmann, Axel Huebl

Computational Radiation Physics

Helmholtz-Center Dresden Rossendorf

Michael Bussmann · Computational Radiation Physics · www.hzdr.de/crp

m.bussmann@hzdr.de

Radiation Tumor Therapy with Beams of Ions

8 X-Ray Beams 2 Ion Beams

m.bussmann@hzdr.de

Oncoray @ Dresden

Oncoray is the

German National Center for

Translational Cancer Research

m.bussmann@hzdr.de

Oncoray @ Dresden

Can we make

this compact &

affordable?

m.bussmann@hzdr.de

Laser-driven

Ion Acceleration

m.bussmann@hzdr.de

DRACO High-Power Laser

25 x 10-15 seconds pulse duration

2 x 1014 Watts peak power

10 x worldwide power consumption

200000000000000 W

0.000000000000025 s

Compact High Power Lasers

m.bussmann@hzdr.de

How does one accelerate Ions with Lasers?

Power Laser

Metal Foil

m.bussmann@hzdr.de

The Working Horse ─ Target Normal Sheath Acceleration

Laser ionizes target front

side up to critical density

Electrons accelerated by

laser force in bunches

(10-100 fs time scale)

m.bussmann@hzdr.de

Electrons form sheath

at rear surface

Energy transfer from

electrons to ions

m.bussmann@hzdr.de

First dose-controlled Laser-Proton-Irradiation of Cancer Cells

m.bussmann@hzdr.de

A compact, isochronous Gantry using Pulsed Magnets

m.bussmann@hzdr.de

Spread-out Bragg-Peak Irradiation with Broad Energy Beams

The flatter the dose plateau,

the better the dose control

m.bussmann@hzdr.de

In Reality, this will look nicer

m.bussmann@hzdr.de

Oncoray @ Dresden

Yes, we can

(probably)

m.bussmann@hzdr.de

Oncoray @ Dresden

So, what do you

do with GPUs?

m.bussmann@hzdr.de

3D3V Particle-in-Cell Code

Fully GPU-accelerated C++

Open Source

See picongpu.hzdr.de

m.bussmann@hzdr.de

Plasma Simulation using the Particle-in-Cell Technique

Field Domain Particle Domain

m.bussmann@hzdr.de

Creating vectorized Data Structures for Particles and Fields

Field Domain Particle Domain

Cell 1 Cell 1

Cell 2 Cell 4

m.bussmann@hzdr.de

Thread-wise Operations on Fields and Particles in Shared Memory

Cell 1 Cell 1

Cell 2 Cell 4

THREAD BLOCK

THREAD 1 THREAD 2 THREAD 4 THREAD 3

m.bussmann@hzdr.de

Task-Parallel Execution of Kernels + Asynchronous Communication

m.bussmann@hzdr.de

Particle-in-Cell

GPU-only code!

m.bussmann@hzdr.de

Oncoray @ Dresden

Does it work?

m.bussmann@hzdr.de

Targets must be held by „something“

Before laser pulse 100 ps after laser pulse

m.bussmann@hzdr.de

Sometimes, you just need a little force…

m.bussmann@hzdr.de

100µm

Levitating Targets in a Paul Traps

m.bussmann@hzdr.de

Simulating levitating Targets on TITAN

Five 3D Simulations (+many 2D)

100 nc, resolving lplasma

1 ps duration @ as resolution

ORNL INCITE Highlight

m.bussmann@hzdr.de

Validation ─ Diffraction of Laser on Target

Simulation

Experiment

m.bussmann@hzdr.de

Thank you!

compact cancer killers simulating next-generation laser...

Documents

teoría serial killers

serial killers presentation

serial killers sgp

seo killers uncovered

bidis: the candy covered killers the candy covered killers

monsters, killers & misconceptions

scavenger killers

2005 columbine killers

pain killers

simulating solar-induced chlorophyll fluorescence in...

simulating interplanetary transponder and laser

the5 mostchallengingprofit killers

serial killers info · 2018. 2. 5. · serial killers info

disposable killers

volcanoes beautiful killers

male serial killers

the killers

marriage killers

5 passion killers

killers - sam's town.pdf