copyright © 2009 pearson education, inc. chapter 10 lecture concepts of genetics tenth edition dna...
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Copyright © 2009 Pearson Education, Inc.
Chapter 10 Lecture
Concepts of GeneticsTenth Edition
DNA Structure and Analysis
Copyright © 2009 Pearson Education, Inc.
10.1 The Genetic Material Must Exhibit Four Characteristics
Replication
Storage of information
Expression of information
Variation by mutation
Copyright © 2009 Pearson Education, Inc. Figure 10.1
Copyright © 2009 Pearson Education, Inc.
10.2 Until 1944, Observations Favored Protein as the Genetic Material
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Copyright © 2009 Pearson Education, Inc.
10.3 Evidence Favoring DNA as the Genetic Material Was First Obtained during the Study of Bacteria and Bacteriophages
10.3.1 Transformation: Early Studies
Copyright © 2009 Pearson Education, Inc. Figure 10.2
Copyright © 2009 Pearson Education, Inc. Table 10.1
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10.3 Evidence Favoring DNA as the Genetic Material Was First Obtained during the Study of Bacteria and Bacteriophages
10.3.2 Transformation: The Avery, MacLeod, and McCarty Experiment
Copyright © 2009 Pearson Education, Inc. Figure 10.3
Copyright © 2009 Pearson Education, Inc.
10.3 Evidence Favoring DNA as the Genetic Material Was First Obtained during the Study of Bacteria and Bacteriophages
10.3.3 The Hershey–Chase Experiment
Copyright © 2009 Pearson Education, Inc. Figure 10.4
Copyright © 2009 Pearson Education, Inc. Figure 10.5
Copyright © 2009 Pearson Education, Inc.
10.3 Evidence Favoring DNA as the Genetic Material Was First Obtained during the Study of Bacteria and Bacteriophages
10.3.4 Transfection Experiments
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10.4 Indirect and Direct Evidence Supports the Concept that DNA Is the Genetic Material in Eukaryotes
10.4.1 Indirect Evidence: Distribution of DNA
10.4.2 Indirect Evidence: Mutagenesis
Copyright © 2009 Pearson Education, Inc. Table 10.2
Copyright © 2009 Pearson Education, Inc. Figure 10.6
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10.4 Indirect and Direct Evidence Supports the Concept that DNA Is the Genetic Material in Eukaryotes
10.4.3 Direct Evidence: Recombinant DNA Studies
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10.5 RNA Serves as the Genetic Material in Some Viruses
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10.6 Knowledge of Nucleic Acid Chemistry Is Essential to the Understanding of DNA Structure
10.6.1 Nucleotides: Building Blocks of Nucleic Acids
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Copyright © 2009 Pearson Education, Inc. Figure 10.7
Copyright © 2009 Pearson Education, Inc. Figure 10.7a
Copyright © 2009 Pearson Education, Inc. Figure 10.7b
Copyright © 2009 Pearson Education, Inc. Figure 10.8
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10.6 Knowledge of Nucleic Acid Chemistry Is Essential to the Understanding of DNA Structure
10.6.2 Nucleoside Diphosphates and Triphosphates
Copyright © 2009 Pearson Education, Inc. Figure 10.9
Copyright © 2009 Pearson Education, Inc.
10.6 Knowledge of Nucleic Acid Chemistry Is Essential to the Understanding of DNA Structure
10.6.3 Polynucleotides
Copyright © 2009 Pearson Education, Inc. Figure 10.10
Copyright © 2009 Pearson Education, Inc. Figure 10.10a
Copyright © 2009 Pearson Education, Inc. Figure 10.10b
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10.7 The Structure of DNA Holds the Key to Understanding Its Function
10.7.1 Base-Composition Studies
10.7.2 X-Ray Diffraction Analysis
Copyright © 2009 Pearson Education, Inc. Table 10.3
Copyright © 2009 Pearson Education, Inc. Figure 10.11
Copyright © 2009 Pearson Education, Inc.
Copyright © 2009 Pearson Education, Inc.
10.7 The Structure of DNA Holds the Key to Understanding Its Function
10.7.3 The Watson–Crick Model
Copyright © 2009 Pearson Education, Inc. Figure 10.12
Copyright © 2009 Pearson Education, Inc. Figure 10.12a
Copyright © 2009 Pearson Education, Inc. Figure 10.12b
Copyright © 2009 Pearson Education, Inc. Figure 10.12c
Copyright © 2009 Pearson Education, Inc. Figure 10.13
Copyright © 2009 Pearson Education, Inc. Figure 10.14
Copyright © 2009 Pearson Education, Inc.
10.8 Alternative Forms of DNA Exist
Copyright © 2009 Pearson Education, Inc. Figure 10.15
Copyright © 2009 Pearson Education, Inc. Figure 10.15a
Copyright © 2009 Pearson Education, Inc. Figure 10.15b
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10.9 The Structure of RNA Is Chemically Similar to DNA, but Single Stranded
Copyright © 2009 Pearson Education, Inc. Table 10.4
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10.10 Many Analytical Techniques Have Been Useful during the Investigation of DNA and RNA
10.10.1 Absorption of Ultraviolet Light (UV)
10.10.2 Sedimentation Behavior
Copyright © 2009 Pearson Education, Inc. Figure 10.16
Copyright © 2009 Pearson Education, Inc.
10.10 Many Analytical Techniques Have Been Useful during the Investigation of DNA and RNA
10.10.3 Denaturation and Renaturation of Nucleic Acids
Copyright © 2009 Pearson Education, Inc. Figure 10.17
Copyright © 2009 Pearson Education, Inc.
10.10 Many Analytical Techniques Have Been Useful during the Investigation of DNA and RNA
10.10.4 Molecular Hybridization
Copyright © 2009 Pearson Education, Inc. Figure 10.18
Copyright © 2009 Pearson Education, Inc.
10.10 Many Analytical Techniques Have Been Useful during the Investigation of DNA and RNA
10.10.5 Fluorescent in situ Hybridization (FISH)
Copyright © 2009 Pearson Education, Inc. Figure 10.19
Copyright © 2009 Pearson Education, Inc.
10.10 Many Analytical Techniques Have Been Useful during the Investigation of DNA and RNA
10.10.6 Reassociation Kinetics and Repetitive DNA
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C/C0 = 1/(1+kC0t)
Copyright © 2009 Pearson Education, Inc.
Copyright © 2009 Pearson Education, Inc.
Copyright © 2009 Pearson Education, Inc.
Copyright © 2009 Pearson Education, Inc.
10.10 Many Analytical Techniques Have Been Useful during the Investigation of DNA and RNA
10.10.7 Electrophoresis of Nucleic Acids
Copyright © 2009 Pearson Education, Inc. Figure 10.20
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