patient specific qc in aarhus

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Patient specific QC in Aarhus. Lone Hoffmann Ulrik Vindelev Elstrøm, Mai-Britt Kyed Jørgensen. VMAT introduction. Introduced in May 2009 First patient: June the 17th, 2009 Treated approx. 800 patients Primarily pelvic cancers Prostate, cervix, bladder, anal, rectum,.. Other types: - PowerPoint PPT Presentation

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Patient specific QC in Aarhus

Lone HoffmannUlrik Vindelev Elstrøm, Mai-Britt Kyed Jørgensen

VMAT introduction

Introduced in May 2009 First patient: June the 17th, 2009 Treated approx. 800 patients Primarily pelvic cancers

Prostate, cervix, bladder, anal, rectum,..

Other types: Brain, sarcomas, abdominal

Patient specific QA

Perform Delta4 verification for all patients Normalization to daily output Gamma(3,3) > 95 % Most patients: G(3,3) > 97 %

Test/learning plans

10 prostate plans (15MV)were created with: 250MU, 500MU, 750Mu, 1000MU, 2000MU In 1 or 2 arcs

10 H&N plans (6MV) were created with: 250MU, 500MU, 750Mu, 1000MU, 2000MU In 1 or 2 arcs

2 Gy/fx

G(3,3) vs. #MUs G(3,3) decreases as a function of MUs Planning criteria: MU < 400 for 1/2 arcs

G(3,3) vs. accelerator

Differences between accelerators

Test plans used for QA 6 of the test plans are use for QA 4 times a year each acc. Plans with high G(3,3) are very stable (within 2-4%)

acc7

80

85

90

95

100

06-07-2009

22-01-2010

10-08-2010

26-02-2011

14-09-2011

01-04-2012

Prost1 250Tonsil1 250Prost2 500Tonsil2 500Prost1 2000Tonsil1 2000 Low/moderate modulation

High modulation

Test plans used for QA

Some accelerators are more stable than others Acc1 performs bad in autumn 2011 – no

problems with mashine QC

Test_RI_Prost2, 15MV, 500MU, Gamma(3,3)

90

91

92

93

94

95

96

97

98

99

100

06-07-2009

14-10-2009

22-01-2010

02-05-2010

10-08-2010

18-11-2010

26-02-2011

06-06-2011

14-09-2011

23-12-2011

01-04-2012

Acc 2

Acc 5

Acc 6

Acc 9

Acc 3

Test_RI_Prost2, 15MV, 500MU, Gamma(3,3)

90

91

92

93

94

95

96

97

98

99

100

06-07-2009

14-10-2009

22-01-2010

02-05-2010

10-08-2010

18-11-2010

26-02-2011

06-06-2011

14-09-2011

23-12-2011

01-04-2012

Acc 1

Acc 4

Acc 7

Acc 10

Acc 8

Acc QC vs. Patient spec QC

Problems with acc QC on acc 5 (spring 2011) Not seen for patient specific QC

-0.2

0

0.2

0.4

0.6

0.8

1

1.2

1.4

1.6

0 100 200 300 400 500 600 700

Pixel

No

rm

Leaf 30 Leaf 30 baggrund

Acc5 Gamma(3,3)

90

91

92

93

94

95

96

97

98

99

100

06-07-2009

14-10-2009

22-01-2010

02-05-2010

10-08-2010

18-11-2010

26-02-2011

06-06-2011

14-09-2011

23-12-2011

Prost2 500

Tonsil2 500

Prost1 250

Tonsil1 250

Low dose rate

DRMLC test

86

88

90

92

94

96

98

100

0 5 10 15 20 25

Different patients

G(3

,3)

Acc 4 08-04-2010Acc 6 08-09-2010Acc4 08-17-2010Acc 4 08-18-2010Acc 6 08-19-2010Acc 8 08-23-2010Acc 8 08-25-2010Acc10 09-02-2010Acc3 10-14-2010Acc 6 11-11-2010

Real patient plans Reproducibility for each acc Difference between acc – not seen with acc QC

acc3

True beam

5 patients treated at Clinac and True beam G(3,3) does not depend on Clinac/True beam?

MeanG(Clinac)=98.4% MeanG(TrueBeam)=99.0%

Portal dosimetry Use EPID/MVD for patient specific QC Fast measurement Ideal for routine measurements

127 Single arcs G(3,3)

80,0

85,0

90,0

95,0

100,0

80,0 85,0 90,0 95,0 100,0

Delta4

PD

I

Single arcs G(3,3) Unity Composite G(3,3)

Delta4 vs. PDI Perform Delta4 and PDI measurement consecutively at

same accelerator Preliminary results, Oct-Dec 2011:

68 plans (1,2, ..6 arcs) 127 single arcs

Single arcs G(3,3)D4: 1.7% higher than G(3,3)PDI

Plans G(3,3)D4: 1.0% higher than G(3,3)PDI

Pass criteria: G(3,3)D4: 95% G(3,3)PDI: 94%

Work in Progress Measurement of D4 and PDI for same plan at

different accelerators Analysis of data (approx 100 plans and 10 new

plans pr week) Workflow today:

Daily PDI; used for accept/reject Weekly D4; used for check

Future: Only PDI New/additional machine QC program

Machine QC program

MV imager:Test of ”clinical” dose ratesTest of reverse gantry direction

Test of gantry position Delta4

Still of measurement of 6 test plans 4xyear each accelerator

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