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1st EMF-Med World Conference on Biomedical Applications of Electromagnetic Fields
& COST EMF-MED Final Event with 6th MCM
Split, 10-13 September 2018
PROGRAM &
Local Information
1
Organized By:
FESB, University of Split
Co-organized by:
• COST EMF-MED • European BioElectromagnetics Association (EBEA) • School of Medicine, University of Split (MEFST)
Endorsed by:
• International Federation for Medical and Biological Engineering (IFMBE)
• International Neuromodulation Society (INS) • The Bioelectromagnetics Society (BEMS) • European Society for Hyperthermic Oncology (ESHO) • Croatian Biomedical Engineering and Medical Physics
Society (CROBEMPS) • IEEE Croatia Section • IEEE Engineering in Medicine and Biology Croatia Chapter • IEEE Electromagnetic Compatibility Society Croatia
Chapter • IEEE Antennas and Propagation Society Croatia Chapter • IEEE Microwave Theory and Techniques Croatia Chapter
Venue:
FESB, University of Split, Ruđera Boškovića 32, 21000 Split, CROATIA Contact: cost-emf-med@fesb.hr Conference Wi-Fi: "EMFMed", password: EMFMed2018 Eduroam is also available.
2
COMMITTEES
Organizing Committee / TPC Chairs:
• Antonio Šarolić (Croatia), Conference Chair • Mirjana Moser (Switzerland), Conference co-Chair • Gerard van Rhoon (The Netherlands) • Lluis Mir (France) • Niels Kuster (Switzerland) • Stavros Koulouridis (Greece)
Technical Program Committee:
Marioara Avram, Romania Almir Badnjević, Bosnia and
Herzegovina Jan Barabas, Slovakia John Bolte, The Netherlands Maria Inês Carvalho, Portugal Antonino Cassarà, Switzerland Raúl Chávez-Santiago, Norway Darko Chudy, Croatia Michal Cifra, Czech Republic Vedrana Čikeš Čulić, Croatia Jean-Francois Collard, Belgium Raquel Conceição, Portugal Luis Correia, Portugal Jan Cuppen, Netherlands Guglielmo d'Inzeo, Italy Nikola Djurić, Serbia Nebojsa Doncov, Serbia Lourdes Farrugia, Malta Peter Gajšek, Slovenia Nevzat Gençer, Turkey Dirk Geschwentner, Germany Motti Haridim, Israel Istvan Hernadi, Hungary Hiie Hinrikus, Estonia Andreas Ioannides, Cyprus Jukka Juutilainen, Finland Eugenijus Kaniusas, Austria
Leonardo Kapural, USA Jolanta Karpowicz, Poland Adnan Kaya, Turkey Leena Korpinen, Finland Stavros Koulouridis, Greece Niels Kuster, Switzerland Jaanus Lass, Estonia James Lin, USA Carmela Marino, Italy Natasa Markovska, FYR Macedonia Luc Martens, Belgium Arvydas Martinkenas, Lithuania Michael Mattes, Denmark Mats-Olof Mattsson, Sweden Alastair McKinlay, United Kingdom Simona Miclaus, Romania Damijan Miklavčič, Slovenia Lluis Mir, France Mihaela Morega, Romania Mirjana Moser, Switzerland Konstantina Nikita, Greece Martin O'Halloran, Ireland Yoram Palti, Israel Smiljana Paraš, Bosnia and
Herzegovina Leandro Pecchia, United Kingdom Daniela Pencheva, Bulgaria Yann Percherancier, France
3
Mikael Persson, Sweden Azadeh Peyman, United Kingdom Dragan Poljak, Croatia Nada Pop-Jordanova, FYR
Macedonia Victoria Ramos, Spain Giuseppe Ruvio, Ireland Theodoros Samaras, Greece Charles Sammut, Malta Damir Sapunar, Croatia Antonio Šarolić, Croatia
José L. Sebastián, Spain Hartwig Siebner, Denmark Myrtill Simko, Sweden Michal Teplan, Slovakia György Thuróczy, Hungary Hubert Trzaska, Poland Gerard van Rhoon, Netherlands Lyubina Vesselinova, Bulgaria David Vrba, Czech Republic Jonna Wilén, Sweden Gunde Ziegelberger, Germany
PROGRAM OUTLINE
Sunday, 9 September
16:00 - 20:00 Registration
Monday, 10 September
08:00 - 09:15 Registration
09:15 - 09:30 Conference Opening
09:30 - 18:00 Technical Program
18:00 - 20:00 Welcome cocktail
Tuesday, 11 September
09:00 - 17:00 Technical Program
17:15 - 19:30 COST Action BM1309 (EMF-MED) 6th Management Committee Meeting
Wednesday, 12 September
09:00 - 18:00 Technical Program
19:30 - 23:00 Conference dinner
Thursday, 13 September
09:00 - 11:00 Technical Program
11:30 - 12:30 Short courses
12:30 - 13:00 Closing ceremony
4
S
unda
y,
Sep
tem
ber 9
M
ond
ay,
Sept
embe
r 10
T
uesd
ay,
Sept
embe
r 11
W
edne
sday
, S
epte
mbe
r 12
T
hurs
day,
S
epte
mbe
r 13
8:
00 -
9:00
Reg
istr
atio
n
9:00
- 9:
15
K
N4:
EM
F in
CO
ST
A
ctio
ns: f
rom
risk
s to
be
nefit
s
KN
6: C
halle
nges
of
med
ical
dev
ices
usi
ng
EMF
for
publ
ic h
ealth
K
N10
: Ele
ctro
pora
tion
appl
icat
ions
in m
edic
ine:
fr
om f
unda
men
tals
to th
e cl
inic
s 9:
15 -
9:30
Con
fere
nce
Ope
ning
KN
7: E
MF
expo
sure
fro
m
med
ical
/cos
met
ic
devi
ces:
Are
sta
ndar
ds
need
ed?
9:30
- 10
:00
K
N1:
EM
F-M
ed:
Elec
trom
agne
tic m
edic
ine
- a p
rom
ise
for
the
futu
re
S3:
Ben
efic
ial
inte
ract
ions
of
EMFs
w
ith b
iolo
gica
l sy
stem
s
S7:
Ele
ctro
mag
netic
sa
fety
of
med
ical
de
vice
s an
d pr
oced
ures
S12:
Cel
lula
r-le
vel
inte
ract
ions
with
pul
sed
EMFs
S
13: N
anop
artic
les
in E
MF-
Med
app
licat
ions
10:0
0 - 1
0:15
K
N2:
Vag
us n
erve
st
imul
atio
n 10
:15
- 10:
30
Rou
nd ta
ble:
WH
O a
nd
EMF-
Med
: Wha
t can
ea
ch c
ontr
ibut
e?
10:3
0 - 1
0:45
C
offe
e br
eak
Cof
fee
brea
k 10
:45
- 11:
00
Cof
fee
brea
k 11
:00
- 11:
15
KN
3: E
mer
ging
wav
efor
ms
in s
pina
l cor
d st
imul
atio
n fo
r co
ntro
l of
chro
nic
pain
KN
5: A
n ov
ervi
ew o
f m
edic
al m
icro
wav
e im
agin
g C
offe
e br
eak
11:1
5 - 1
1:30
K
N8:
Rea
lizin
g th
e vi
sion
of
a v
erifi
ed &
val
idat
ed
com
puta
tiona
l ne
uros
timul
atio
n pl
atfo
rm
11:3
0 - 1
1:45
S1:
Neu
ral E
MF
appl
icat
ions
and
in
tera
ctio
ns
S4:
Mic
row
ave
Med
ical
(M
iMed
) Im
agin
g
SC1:
App
licat
ion
of
mac
hine
lear
ning
to
med
ical
dat
a
SC2:
Neu
roim
agin
g te
chni
ques
in c
ombi
natio
n w
ith T
rans
cran
ial
Mag
netic
Stim
ulat
ion
(TM
S):
sta
te o
f th
e ar
t and
fu
ture
per
spec
tives
11:4
5 - 1
2:30
S
8: E
xper
imen
tal s
etup
s an
d m
odel
s fo
r EM
F-M
ed
rese
arch
5
12:3
0 - 1
2:45
C
losi
ng c
erem
ony
12:4
5 - 1
3:00
Lu
nch
13:0
0 - 1
4:00
Lu
nch
Lunc
h Lu
nch
14:0
0 - 1
4:45
Pos
ter s
essi
on
S5:
Ele
ctro
mag
netic
-ba
sed
The
rmal
T
hera
pies
(C
OST
A
ctio
n M
yWA
VE)
S9: E
MF
tech
nolo
gies
for
re
mot
ely
pow
erin
g w
eara
ble
and
impl
anta
ble
devi
ces
14:4
5 - 1
5:30
S10
: Ele
ctro
mag
netic
sa
fety
of
med
ical
im
plan
ts in
MR
I and
m
edic
al W
PT
te
chno
logi
es
15:3
0 - 1
6:00
C
offe
e br
eak
Cof
fee
brea
k C
offe
e br
eak
16:0
0 - 1
6:30
Reg
istr
atio
n,
post
ers
mou
ntin
g
S2: E
M-b
ased
m
icro
man
ipul
atio
n of
ce
lls: t
owar
ds
unpr
eced
ente
d ap
plic
atio
ns in
med
icin
e an
d bi
olog
y
S6:
Die
lect
ric a
nd
mag
netic
pro
pert
ies
of b
iolo
gica
l mat
eria
ls K
N9:
Ele
ctro
mag
netic
hy
pert
herm
ia:
Inno
vatio
ns a
nd c
linic
al
appl
icat
ions
16
:30
- 17:
00
S11
: Ele
ctro
mag
netic
hy
pert
herm
ia
17:0
0 - 1
7:15
17:1
5 - 1
8:00
C
OST
Act
ion
BM
1309
(E
MF-
MED
) 6t
h M
anag
emen
t C
omm
ittee
Mee
ting
18:0
0 - 1
9:30
W
elco
me
cock
tail
19:3
0 - 2
0:00
Con
fere
nce
dinn
er
20:0
0 - 2
3:00
6
WELCOME MESSAGE FROM THE CONFERENCE CHAIR
Dear EMF-Med 2018 Participants,
Welcome to beautiful Split, welcome to the first ever EMF-Med World Conference on Biomedical Applications of Electromagnetic Fields! In a way, you are taking part in history making.
This conference was devised to serve as a vehicle, both driven by the expanding EMF-Med research and innovations, and providing a boost for them. Inspired by promising recent ideas and studies, EMF-Med focuses on medically applicable effects of EMFs, aiming for breakthrough results, new discoveries and innovative biomedical technologies.
Systematical approach to EMF-Med applications requires a dedicated community - a world-wide concerted R&D network - to sustain the required interdisciplinary knowledge: underlying biological mechanisms, knowledgeable engineering, reliable setups - having medical applications and patient benefit as the final goal. The EMF-Med Training School was also established to further sustain both the network and the knowledge.
The conference is also the final event of a research coordination project COST EMF-MED: European network for innovative uses of EMFs in biomedical applications. It ends soon, after having involved 35 countries and 350+ researchers. It started as a shy but bold idea in 2012 – to start the very first research initiative in the world to systematically and comprehensively approach the topic of beneficial effects of EMFs. This conference proves the ultimate success of this idea.
Wishing you a nice time in beautiful Split, and lots of ideas for the next conference,
Sincerely,
Antonio Šarolić Conference Chair on behalf of the Organizing Committee
7
KEYNOTE LECTURES
"EMF-Med: Electromagnetic medicine - a promise for the future" Prof. Antonio Šarolić, PhD Chair of COST EMF-MED; Professor of Electrical Engineering, FESB, University of Split, Croatia
"Vagus nerve stimulation" Peter S. Staats, MD, MBA Chief Medical Officer, National Spine and Pain Centers, USA
"Emerging waveforms in spinal cord stimulation for control of chronic pain" Leonardo Kapural, MD, PhD Pain Physician, Carolinas Pain Institute and Center for Clinical Research; Professor of Anesthesiology, Wake Forest University, School of Medicine, USA
"EMF in COST Actions: from risks to benefits" Mirjana Moser, PhD COST EMF-MED Vice-Chair, Switzerland
"An Overview of Medical Microwave Imaging" Raquel Cruz Conceição, PhD Instituto de Biofísica e Engenharia Biomédica, Faculdade de Ciências da Universidade de Lisboa, Campo Grande, 1749-016-Lisbon, Portugal
8
"Challenges of medical devices using EMF for public health" Adriana Velázquez Berumen Senior Advisor and Focal Point for Medical Devices; Essential Medicines and Health Products department, World Health Organization (WHO), Geneva, Switzerland "EMF exposure from medical/cosmetic devices: Are standards needed?" Emilie van Deventer, PhD Team Leader, Radiation Programme, World Health Organization (WHO), Geneva, Switzerland
"Realizing the Vision of a Verified & Validated Computational Neurostimulation Platform" Prof. Niels Kuster, PhD COST EMF-MED WG3 Leader; Foundation for Research on Information Technologies in Society (IT’IS), Zurich, Switzerland; Swiss Federal Institute of Technology (ETH) Zurich, Switzerland
"Electromagnetic hyperthermia: Innovations and clinical applications" Prof Gerard van Rhoon, PhD COST EMF-MED WG1 Leader; Erasmus MC Cancer Institute, The Netherlands "Electroporation applications in medicine: from fundamentals to the clinics" Lluis M. Mir, DRCE CNRS COST EMF-MED WG2 Leader; Vectorology and Anticancer Therapies, UMR 8203 CNRS – University Paris-Saclay, France
9
CONFERENCE PROGRAM
Sunday, 9 September
Sunday, 9 September, 16:00 - 20:00 Room: Atrium
Registration
Monday, 10 September
Monday, 10 September, 8:00 - 9:15 Room: Atrium
Registration
Monday, 10 September, 9:15 - 9:30 Room: A100
Conference Opening
Monday, 10 September, 9:30 - 10:00 Room: A100
Keynote lecture KN1:
EMF-Med: Electromagnetic medicine - a promise for the future
Antonio Šarolić
Monday, 10 September, 10:00 - 10:30 Room: A100
Invited keynote lecture KN2:
Vagus nerve stimulation
Peter S. Staats
Monday, 10 September, 10:30 - 11:00 Room: Aquarium
Coffee break
Monday, 10 September, 11:00 - 11:30 Room: A100
Invited keynote lecture KN3:
Emerging waveforms in spinal cord stimulation for control of chronic pain
Leonardo Kapural
10
Monday, 10 September, 11:30 - 13:00 Room: A100
S1: Neural EMF applications and interactions
Chairs: Antonio Šarolić and Eugenijus Kaniusas 11:30 Patch-clamp recordings of strength-duration and strength-frequency curves in rat DRG neurons Alexandru Deftu, Damir Sapunar and Antonio Šarolić 11:45 Computational analysis of neural stimulation thresholds for several charge-balanced biphasic waveforms: a case study Antonio Šarolić, Dujo Benja, Marija Kovačić and Matej Kuliš 12:00 Assessment of nerve cathodal block for the percutaneous auricular vagus nerve stimulation Amine Samoudi, Tom Van de Steene, Emmeric Tanghe, Luc Martens and Wout Joseph
12:15 Individualized models of transcranial stimulation: connecting electrophysiological experiments with electric fields Ilkka Laakso and Marko Mikkonen
12:30 Comparison between direct electrical and optogenetic subthalamic nucleus stimulation Ruben Schoeters, Thomas Tarnaud, Wout Joseph, Luc Martens, Robrecht Raedt and Emmeric Tanghe
12:45 Brain stimulation by modulated microwave radiation: a feasibility study Maie Bachmann, Jaanus Lass, Andreas Ioannides and Hiie Hinrikus
Monday, 10 September, 13:00 - 14:00 Room: Aquarium
Lunch
Monday, 10 September, 14:00 - 15:30 Room: Aquarium
Poster session
Chairs: Stavros Koulouridis and Mirjana Moser P1 Repetitive transcranial magnetic stimulation can improve anxiety in Parkinson's disease: a randomized, double-blind and controlled trial Norbert Kovács, Endre Pál, Dávid Pintér, Márton Kovács and Attila Makkos
11
P2 Auricular vagus nerve stimulation affects fractality of the human body as resolved by advanced ECG Vaiva Siauciunaite, Eugenijus Kaniusas, Stefan Kampusch, Jozsef Constantin Szeles and Alfonsas Vainoras P3 Sensation and pain thresholds of transcranial stimulation with direct and alternating electric current Eugen Kvasnak and Kine Haldorsen Haugen P4 Peak-projection algorithm to target the phase of cortical oscillations in real-time Leo Tomašević and Hartwig Siebner P5 Assessment on electromagnetic hot-spots exposure caused by media control smart metering in a healthcare environment Victoria M Ramos, Angeles Trillo, Jose Hernandez, J Rabasa and Jolanta Karpowicz P6 Evaluation of the effect caused by hearing implants on SAR in a body approaching an RFID reader emitting at a frequency of 13.56 MHz Patryk Zradziński, Jolanta Karpowicz and Krzysztof Gryz P7 Role of magnetic flux density in LF EMF experiments targeting Ca2+, Na+ and K+ ions Jan Barabas, Roman Radil and Ladislav Janousek P8 Impedance measurement of bipolar stimulation electrodes immersed in medium Antonio Šarolić, Ivan Škalic, Alexandru Deftu and Damir Sapunar P9 Viability of human glioblastoma cell line LN229 exposed to rotating magnetic field Anton Kordić, Ornella Kordić, Vedrana Čikeš Čulić and Antonio Šarolić P10 Design and use of phased array RF systems for loco-regional hyperthermia of deep seated tumors Johannes Crezee, Remko Zweije and Petra Kok P11 Impact of segmentation detail in hyperthermia treatment planning: comparison between detailed and clinical tissue segmentation Iva Ribeiro, Netteke van Holthe, Gerard C. van Rhoon and Margarethus M. Paulides
12
P12 Modeling of Joule heating in tissues induced by high- and low-voltage pulse combinations for gene electrotransfer Igor Lacković P13 Linear Regression for Estimating Bladder Volume with Voltage Signals Eoghan Dunne, Adam Santorelli, Brian McGinley, Martin O'Halloran and Emily Porter P14 Multiclass SVM for Bladder Volume Monitoring using Electrical Impedance Measurements Adam Santorelli, Eoghan Dunne, Emily Porter and Martin O'Halloran P15 Cell viability changes in cultured H4 glioma cells upon low frequency pulsed electromagnetic field (7Hz, 30mT) exposure in flow cytometry analysis Jolanta Kaszuba-Zwoińska, Bernadeta Nowak, Piotr Guzdek and Krzysztof Gil P16 MRI compatible robotic system carrying a radio frequency probe to be used for brain ablation Christakis Damianou, Marinos Giannakou and Georgios Menikou P17 Effects of extremely low frequency electromagnetic fields on stem cells are not caused by zinc ions Alp Özgün and Bora Garipcan P18 Effects of radiofrequency fields on RAS and ERK kinases activity in live cells using the real-time Bioluminescence Resonance Energy Transfer (BRET) technique Emmanuelle Poque, Delia Arnaud-Cormos, Lorenza Patrignoni, Hermanus Ruigrok, Florence Poulletier De Gannes, Annabelle Hurtier, Rémy Renom, Lagroye Isabelle, Bernard Veyret, Philippe Leveque and Yann Percherancier P19 Cisplatin in-vitro activity with co-exposure to MRI Pol-Edern Le Renard, Benedikt Nimmervoll, Franz Fellner and Peter Oppelt P20 Strange effects of EMFs on living organisms Wlodzimierz Klonowski P21 Pancreatic β-cell hubs are more resistant to the environmental electromagnetic fields compared with non-hub cells: A computational study Sajjad Farashi, Pezhman Sasanpour and Hashem Rafii-Tabar
13
P22 Efficiency of Matrix Pencil Method in Stimulus Artifact Removal Zied Mizouri, Khalil El Khamlichi Drissi, Lenaïc Monconduit, Christophe Pasquier, Benoît Sion and François Gabrielli P23 Semi-rigid antenna working in ISM 2.4GHz used in microwave ablation Pawel Cala, Paweł Bieńkowski and Hubert Trzaska P24 50 Hz magnetic field affects heart rate variability - an experimental study Tarmo Koppel, Inese Vilcane and Mikko Ahonen P25 Modelling of therapeutic cold plasma generator using finite element method Ivan Moštak, Domagoj Prebeg and Mario Cifrek P26 Electrophysiological characterization of neurons after chronic compression of the dorsal root ganglion Tihana Marcius, Alexandru Deftu and Damir Sapunar P27 Patients with active implanted medical devices (AIMDs) and extremely low-frequency magnetic fields at hospital facilities Leena Korpinen and Rauno Pääkkönen P28 Exposure to the extremely low frequency magnetic field causes changes in Calcium flow, HSP70 and glutathione-disulfide reductase expression in breast cancer cells during apoptosis induction Alireza Madjid Ansari, Reyhane Ghadirian, Mahdieh Shokrollahi Barough and Zahra S. Mesbah Moosavi P29 Theranostic instrument based on the combination of low and high frequency EM-bio interaction for bone defects analysis and healing Anders Rydberg, Yongzhi Guo, Jacob Velander, Patrice Humblot, Göran Andersson, Robin Augustine, Mats-Olof Mattsson and Myrtill Simko P30 Simulated Effects of Specific Absorption Rate and Thermal Variations on Keratinocytes and Epidermis Exposed to Radio-Frequency Giacomo Paolini, Diego Masotti and Alessandra Costanzo P31 Comprehensive study of the effects of electromagnetic field exposure on nervous system using insect models Joanna Wyszkowska, Milena Jankowska and Maria Stankiewicz
Monday, 10 September, 15:30 - 16:00 Room: Aquarium
Coffee break
14
Monday, 10 September, 16:00 - 18:00 Room: A100
Special session (convened by Caterina Merla and Cristiano Palego)
S2: EM-based micromanipulation of cells: towards unprecedented applications in medicine and biology
Chairs: Caterina Merla and Cristiano Palego 16:00 Molecular models for the interaction between high intense electric fields and biomolecules Paolo Marracino, Elena della Valle, Micaela Liberti and Francesca Apollonio
16:15 Microdosimetry in Biomedical Applications: Importance of Realistic Models at the Cellular and Subcellular Levels Micaela Liberti, Agnese Denzi, Caterina Merla, Francesca Apollonio, Annalisa De Angelis and Laura Caramazza
16:30 In vivo silencing gene for enhanced green fluorescent protein mediated by a pulsed electromagnetic field Matej Kranjc, Simona Kranjc, Maja Cemazar, Tadej Kotnik, Gregor Sersa and Damijan Miklavcic
16:45 Permittivity measurements of brain cancer cell solutions: towards the electric characterisation of single cancer stem cells Wesam Gamal, Rosanna Pinto, Mirella Tanori, Arianna Casciati, Mariateresa Mancuso, Luca Persano, Giampietro Viola, Sofiane Saada, Barbara Bessette, Fabrice Lalloue, Arnaud Pothier, Cristiano Palego and Caterina Merla
17:00 High-Frequency Dielectrophoresis Characterization of Differentiated vs Undifferentiated Medulloblastoma Cells Rémi Manczak, Sofiane Saada, Mirella Tanori, Arianna Casciati, Claire Dalmay, Barbara Bessette, Gaelle Begaud, Serge Battu, Pierre Blondy, Marie-Odile Jauberteau, Canan Baristiran-Kaynak, Mehmet Kaynak, Cristiano Palego, Caterina Merla, Barbara Tanno, Mariateresa Mancuso, Fabrice Lalloue and Arnaud Pothier
17:15 Single Pulses of Power at 14.5GHZ and a Weighted Slotted Antenna for the Treatment of Barrett's Oesophagus Christopher Paul Hancock
17:30 Cell membrane permeabilization and cell survival after electroporation in acidic media in vitro Tjaša Potočnik, Damijan Miklavcic and Alenka Maček Lebar
15
17:45 Toward a non-viral gene delivery approach for glycogen storage disease type III (GSDIII) therapy Rosella Franconi, Caterina Merla, Adeline Muscat, Doriana Triggiani, Olivia Costantina Demurtas, Elena Illiano, Franck M André, Carmela Marino and Lluis M. Mir
Monday, 10 September, 18:00 - 20:00 Room: Aquarium
Welcome cocktail
Tuesday, 11 September
Tuesday, 11 September, 9:00 - 9:30 Room: A100
Keynote lecture KN4:
EMF in COST Actions: from risks to benefits
Mirjana Moser
Tuesday, 11 September, 9:30 - 10:30 Room: A100
S3: Beneficial interactions of EMFs with biological systems
Chairs: Mats-Olof Mattsson and Myrtill Simko 9:30 Study of gene expression on human keratinocytes after low frequency pulsed electric current stimulation Jean-Francois Collard and Maurice Hinsenkamp
9:45 Immune system activation by low frequency magnetic fields via the molecular sensor stromal interaction molecules (STIM1 and STIM2) Myrtill Simko
10:00 Diagnostic and therapeutic use, and use potential, of millimetre waves and terahertz waves Mats-Olof Mattsson
10:15 Protective effects of RF with different signal modulations in cultured human lymphocytes treated with chemicals Stefania Romeo, Anna Sannino, Olga Zeni, Rita Massa and Maria Rosaria Scarfì
Tuesday, 11 September, 10:30 - 11:00 Room: Aquarium
Coffee break
16
Tuesday, 11 September, 11:00 - 11:30 Room: A100
Invited keynote lecture KN5:
An overview of medical microwave imaging
Raquel Cruz Conceicao
Tuesday, 11 September, 11:30 - 12:45 Room: A100
Convened session (convened by Raquel C. Conceição and Lorenzo Crocco)
S4: Microwave Medical (MiMed) Imaging
Chairs: Raquel C. Conceição and Lourdes Farrugia 11:30 Development of Axillary Region Models based on MRI Segmented Data to Aid Breast Cancer Staging Daniela M. Godinho, Joao Felicio, Nuno Silva, M Lurdes Orvalho, Carlos A. Fernandes and Raquel C. Conceição
11:45 Preliminary Experimental Characterization of Gelatin-Based Tissue-Mimicking Materials for Realistic Breast Phantoms aimed at Microwave Applications Simona Di Meo, Simone Morganti, Lorenzo Pasotti, Michele Conti, Marco Pasian and Giulia Matrone
12:00 In-Vivo Mapping of Human Tissues From Only Amplitude Electromagnetic Data Martina Teresa Bevacqua, Gennaro G. Bellizzi, Lorenzo Crocco and Tommaso Isernia
12:15 Detection of Pneumothorax Using Low Power Microwave Sources Stavros Koulouridis
12:30 Remote mental workload estimation by a bioradar Lesya N. Anishchenko
Tuesday, 11 September, 12:45 - 14:00 Room: Aquarium
Lunch
17
Tuesday, 11 September, 14:00 - 15:30 Room: A100
Convened session (convened by Lourdes Farrugia and Emily Porter)
S5: Electromagnetic-based Thermal Therapies (COST Action MyWAVE)
Chairs: Lourdes Farrugia and Raquel C. Conceição 14:00 Experimental evaluation of the effective ablation zone on ex-vivo bovine liver samples Anna Bottiglieri
14:15 Monitoring of microwave ablation treatment with electrical impedance tomography Konstantinos Katrioplas and Theodoros Samaras
14:30 Quality assurance of MR-guided deep hyperthermia systems: an international multi-institution evaluation Sergio Curto, Tim Mulder, Bassim Aklan, Oliver Mils, Manfred Schmidt, Ulf Lamprecht, Michael Peller, Ruediger Wessalowski, Lars Lindner, Rainer Fietkau, Daniel Zips, Margarethus M. Paulides, Martine Franckena and Gerard C. van Rhoon
14:45 Ex vivo dielectric properties of fat: influence of the experimental conditions on the measured data Laura Farina, Rosanna Pinto, Vanni Lopresto, Giuseppe Ruvio, Luca Vannucci and Marta Cavagnaro
15:00 A study on the variation of dielectric properties of grey matter with temperature Julian Bonello
15:15 The thermic response of biogenic magnetite suspensions to frequencies in the (0.1-3) GHz range Simona Miclaus, Paul Bechet, George Mihai, Ioan I. Ardelean, Cristina Moisescu and Jolanta Karpowicz
Tuesday, 11 September, 15:30 - 16:00 Room: Aquarium
Coffee break
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Tuesday, 11 September, 16:00 - 17:00 Room: A100
S6: Dielectric and magnetic properties of biological materials
Chairs: Azadeh Peyman and Lourdes Farrugia 16:00 An insight into bone dielectric properties variation: a foundation for electromagnetic medical devices Bilal Amin, Muhammad Adnan Elahi, Atif Shahzad, Eoin Parle, Laoise McNamara and Martin O'Halloran
16:15 Measurements of complex permittivity and permeability in the GHz range of magnetotactic bacteria suspensions Lourdes Farrugia, Simona Miclaus, Cristina Moisescu, Ioan I. Ardelean and Charles Sammut
16:30 Modelling of tissue dielectric contribution within the sensing radius of a coaxial probe Alessandra La Gioia, Martin O'Halloran and Emily Porter
16:45 In vivo electrical conductivity imaging of animal tumor model at 7T using electrical properties tomography Prakash Parappurath Vasudevan, Reza Aminzadeh, Nele De Geeter, Benedicte Descamps, Luc Dupré, Wout Joseph and Roel Van Holen
Tuesday, 11 September, 17:15 - 19:30 Room: A100
COST Action BM1309 (EMF-MED) 6th Management Committee Meeting
(only for COST Action BM1309 MC Members)
Wednesday, 12 September
Wednesday, 12 September, 9:00 - 9:15 Room: A100
Invited keynote lecture KN6:
Challenges of medical devices using EMF for public health
Adriana Velazquez Berumen
Wednesday, 12 September, 9:15 - 9:30 Room: A100
Invited keynote lecture KN7:
EMF exposure from medical/cosmetic devices: Are standards needed?
Emilie van Deventer
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Wednesday, 12 September, 9:30 - 10:15 Room: A100
S7: Electromagnetic safety of medical devices and procedures
Chairs: Mirjana Moser and Jolanta Karpowicz 9:30 Progress report: ICNIRP Statement on non-ionizing radiation for cosmetic purposes Rianne Stam, Ken Karipidis, Jacques Abramowicz, Guglielmo d'Inzeo, Adèle Green, Sharon Miller, Tsutomo Okuno and Tim Toivo
9:45 EMF Applications in Cosmetics and Wellness Gregor Dürrenberger, Krisztina Meya, Martin Schmid and Jürg Fröhlich
10:00 The exposimetric study on the radiofrequency exposures caused by the use of medical devices Jolanta Karpowicz, Victoria M Ramos, Krzysztof Gryz and Silvia de Miguel-Bilbao
Wednesday, 12 September, 10:15 - 10:45 Room: A100
Round table: WHO and EMF-Med: What can each contribute?
Wednesday, 12 September, 10:45 - 11:15 Room: Aquarium
Coffee break
Wednesday, 12 September, 11:15 - 11:45 Room: A100
Keynote lecture KN8:
Realizing the vision of a verified & validated computational neurostimulation platform
Niels Kuster
Wednesday, 12 September, 11:45 - 13:00 Room: A100
S8: Experimental setups and models for EMF-Med research
Chairs: Niels Kuster and Antonio Šarolić 11:45 In-Silico Ear Model Based on Episcopic Images for Percutaneous Auricular Vagus Nerve Stimulation Babak Dabiri Razlighi, Stefan Kampusch, Stefan H. Geyer, Van Hoang Le, Florian Thürk, Simon Brenner, Jozsef Constantin Szeles, Wolfgang J. Weninger and Eugenijus Kaniusas
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12:00 An algorithm for posturing computational phantoms Riccardo Scorretti
12:15 3D Printable Solid Tissue-Mimicking Material for Microwave Phantoms Barry McDermott, Emily Porter, Martin O'Halloran, Anup Poudel, Manus Biggs, Nireeksha Karode and Austin Coffey
12:30 Measurement of Weak Low Frequency Electromagnetic Field Effects on Cells Michal Teplan, Martin Bereta, Ivan Bajla, Katarína Bartošová, Tomáš Dermek, Yvonne Haba and Michal Cifra
12:45 Multimodal in vivo imaging of the mouse brain to test theranostic approaches including the biomedical applications of electromagnetic fields Srećko Gajović
Wednesday, 12 September, 13:00 - 14:00 Room: Aquarium
Lunch
Wednesday, 12 September, 14:00 - 14:50 Room: A100
Convened session (convened by Valerio De Santis and Ilaria Liorni)
S9: EMF technologies for remotely powering wearable and implantable devices
Chairs: Valerio De Santis and Ilaria Liorni 14:00 Design of an Experimental Setup for Freely Positionable Coil Pairs for Transcutaneous Energy Transfer Systems Alexander Enssle, Laurenz Bareiss and Nejila Parspour
14:15 Design and Frequency Optimization of a WPT System for Leadless Medical Implants Tommaso Campi, Silvano Cruciani, Valerio De Santis, Francescaromana Maradei and Mauro Feliziani
14:25 Wearable Tag at 2.45 GHz for Continuous Tracking of Patients Activities in Indoor Environments Giacomo Paolini, Francesca Benassi, Diego Masotti and Alessandra Costanzo
14:35 Misalignments Issues in WPT Links for Medical Implants Giuseppina Monti, Laura Corchia, Beatrice Risolo and Luciano Tarricone
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Wednesday, 12 September, 14:50 - 15:30 Room: A100
Convened session (convened by Ilaria Liorni and Valerio De Santis)
S10: Electromagnetic safety of medical implants in MRI and medical WPT technologies
Chairs: Ilaria Liorni and Valerio De Santis 14:50 Assessment of the Risk of Neurostimulation by Low-Frequency EM Exposure in the Presence of Medical Implants Antonino Mario Cassara, Esra Neufeld, Ilaria Liorni and Niels Kuster
15:05 RF-field vs. Induced Heating with Interventional Catheters: a computational investigation Micol Colella, Elena Lucano, Francesca Apollonio, Qi Zeng, Jingshen Liu, Tom Lloyd, Steve Wedan, Ji Chen, Wolfgang Kainz, Micaela Liberti and Leonardo Angelone
15:20 New Mechanistic Model for Implant Safety Assessment at WPT Frequencies Ilaria Liorni, Esra Neufeld, Sven Kuhn and Niels Kuster
Wednesday, 12 September, 15:30 - 16:00 Room: Aquarium
Coffee break
Wednesday, 12 September, 16:00 - 16:30 Room: A100
Keynote lecture KN9:
Electromagnetic hyperthermia: Innovations and clinical applications
Gerard van Rhoon
Wednesday, 12 September, 16:30 - 18:00 Room: A100
S11: Electromagnetic hyperthermia
Chairs: Gerard C. van Rhoon and Mihaela Morega 16:30 Development and In vivo Validation of an MR-Compatible Temperature Controllable Superficial Hyperthermia Applicator for Small Animal Studies Kemal Sumser, Anthony A.V. Geerman, Joost Haeck, Monique Bernsen, Gerard C. van Rhoon and Margarethus M. Paulides
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16:45 Water bolus investigation in conformal array for deep regional hyperthermia Redi Poni, Myles Capstick and Niels Kuster
17:00 Adaptive Treatment Planning for Locoregional Hyperthermia: A Necessary Tool for Optimizing Treatment Quality Petra Kok and Johannes Crezee
17:15 A Feasibility Study of Interstitial Microwaves Ablation and Hyperthermia by Numerical Simulation Mihaela Morega, Alexandru Mihail Morega and Alina Monica Ilie-Sandoiu
17:30 Sparsity Promoted Antenna Selection in Hyperthermia Treatment Planning Gennaro G. Bellizzi, Margarethus M. Paulides, Tomas Drizdal, Gerard C. van Rhoon, Lorenzo Crocco and Tommaso Isernia
17:45 Complex therapy by EMF and fractal physiology Andras Szasz
Wednesday, 12 September, 19:30 - 23:00
Conference dinner at the Cellars of the Diocletian's Palace (directions to the location are given at the end of the Program booklet)
Thursday, 13 September
Thursday, 13 September, 9:00 - 9:30 Room: A100
Keynote lecture KN10:
Electroporation applications in medicine: from fundamentals to the clinics
Lluis M. Mir
Thursday, 13 September, 9:30 - 11:00
S12: Cellular-level interactions with pulsed EMFs Room: A100
Chairs: Lluis M. Mir and Caterina Merla
9:30 Oxidative and Epigenetic Effects of Ultra-short Pulsed electric Fields on Neuronal-like Cells Claudia Consales, Caterina Merla, Barbara Benassi, Adeline Muscat, Tomas Garcia-Sanchez, Carmela Marino and Lluis M. Mir
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9:45 Nanosecond pulsed electric fields modulate Ca2+ fluxes in SHSY-5Y neuroblastoma cell line Caterina Merla, Tomas Garcia-Sanchez, Adeline Muscat, Claudia Consales, Barbara Benassi, Franck M André, Carmela Marino and Lluis M. Mir
10:15 Electrical stimulation increases schwann cells proliferation inside hyaluronic acid conduits Cristina Martinez Ramos, Maria Jose Morillo Bargues, Fernando Gisbert Roca, Laura Rodriguez Doblado, Esther Giraldo, Victoria Moreno and Manuel Monleon
17:45 Sine-wave electropermeabilization Tomas Garcia-Sanchez and Lluis M. Mir
10:30 Long term control of cytosolic calcium oscillations in Mesenchymal Stem Cells using repeated electric pulses Shirmoné Botha, Borja Lopez, Adeline Muscat, Óscar Lucía, Héctor Sarnago, Alejandro Naval, José-Miguel Burdio, Tomas Garcia-Sanchez, Lluis M. Mir and Franck M André
10:45 Zeta potential for monitoring posterior effects of the pulsed electric field in cell suspension Djamel Eddine Chafai and Michal Cifra
S13: Nanoparticles in EMF-Med applications Room: A101
Chairs: Theodoros Samaras and Gerard C. van Rhoon
9:30 Effects of spatial distribution patterns of magnetic nanoparticles on temperature distribution in magnetic hyperthermia Gurmeet Singh, Neeraj Kumar and Pramod Avti
9:45 Ex-vivo evaluation of magnetite magnetic nanoparticles as magnetic hyperthermia carriers Nikos Maniotis, Eirini Myrovali, Zoi Kalpaxidou, Charoula Iliaskou, Makis Angelakeris and Theodoros Samaras
10:00 Regional Focus effect on Magnetic Particle Hyperthermia efficiency Eirini Myrovali, Nikos Maniotis, Antonis Makridis, Kostantinos Simeonidis, Theodoros Samaras and Makis Angelakeris
10:15 Magnetotactic bacteria and biogenic magnetite nanocrystals as potential contrast agents in Magnetic Resonance Imaging Ioan Ardelean, Simona Miclaus, Ioan I. Ardelean and Cristina Moisescu
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10:30 Novel aspects of silver nanoparticles application in low intensity electromagnetic field Daniela Pencheva, Petia Genova-Kalou, Rayna Bryaskova, Lyubina Vesselinova, Todor Kantardjiev and Julian Ivanov Raynov
10:45 Can magnetic nanoparticles thermally assist the beneficiary role of transcranial magnetic stimulation? Tamara Odutola, Eirini Myrovali, Antonis Makridis, Nikos Maniotis, Makis Angelakeris, Vasilios Kimiskidis and Theodoros Samaras
Thursday, 13 September, 11:00 - 11:30 Room: Aquarium
Coffee break
Thursday, 13 September, 11:30 - 12:30
Short course SC1: Room: A101
Application of machine learning to medical data
Raquel Cruz Conceicao, Daniela M. Godinho
Short course SC2: Room: A100
Neuroimaging techniques in combination with Transcranial Magnetic Stimulation (TMS): state of the art and future perspectives
Hartwig Roman Siebner, Leo Tomašević
Thursday, 13 September, 12:30 - 13:00 Room: A100
Closing ceremony
Thursday, 13 September, 13:00 - 14:00 Room: Aquarium
Lunch
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LOCAL INFORMATION
About the city
Split - the Mediterranean city of life, where old meets new: founded as the Roman emperor Diocletian palace, now hosting the leading university in Croatia. It is the second largest city in Croatia, located on the Adriatic coast in the central Dalmatia, on the Split peninsula. A string of islands scattered in the crystal clear blue sea, make a magnificent frame around Split – make sure you take a look from the plane when arriving!
Centrally located on the Adriatic coast and well connected, Split provides the most convenient base to visit nearby beautiful Dalmatian islands, national parks, and other popular destinations like Dubrovnik, Trogir, Sibenik, Zadar, etc. The city is known for its climatic benefits (it has 2700 hours of sun a year), magical shades of the Marjan forest in the west part of the peninsula, and long seaside walkways.
The Diocletian’s Palace (under UNESCO’s protection since 1979), situated in the city center, dates from the 4th century and it is a unique site worldwide. The citizens still treasure traditional customs, leaving a pleasant and world-known feeling of welcome with their unique Mediterranean charm and delicious cuisine. Split, a city with almost 200.000 inhabitants, is one of the most important tourist destinations in Croatia and a significant cultural center.
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Tourist info
Split has recently been awarded as Croatia's Best City Break Destination and Best Destination of the Year 2017. For more information please visit the websites of the:
• Tourist Board of Split: http://visitsplit.com/en/ • Tourist Board of Dalmatia: https://www.dalmatia.hr/en • Tourist Board of Croatia: https://www.croatia.hr
Climate
Split has a Mediterranean climate with hot, moderately dry summers and mild, wet winters (snow is very rare). July is the hottest month, with an average high temperature around 30°C. January is the coldest month, with an average low temperature around 5°C. September is practically a summer month, providing plenty of beach time with more pleasant temperatures (less heat) than July and August (see weather statistics at https://www.yr.no/place/Croatia/Split-Dalmatia/Split/statistics.html ).
Currency
Croatia, although a EU member country, still has its own currency called Kuna (pronounced as koonnah, abbreviated as HRK or locally as "kn"). 1 Euro is worth approximately 7.4 Kuna. The currency can be exchanged in numerous change offices. The credit cards are widely accepted. However, tickets for the public transport can be paid by HRK cash only.
HOW TO GET TO SPLIT
By plane
Split is a highly popular tourist destination, served by Split Airport: http://www.split-airport.hr/. With ever increasing popularity of the destination, there is a wide selection of airlines during the summer season (September included). Split Airport (Zračna luka Split, code: SPU) is located 25 km from Split.
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The airport is connected to the Split main bus terminal (Autobusni kolodvor Split, situated in the city center), by shuttle bus. Shuttle ticket fare is 30 HRK ≈ 4 € for one direction, can be bought from the driver, only in HRK. There is also the option of online purchase at http://plesoprijevoz.hr/en/. The shuttle timetable can be found at: http://plesoprijevoz.hr/ page/timetable#split
The taxi fare Airport<->Split averages to ca. 250HRK ≈ 33€, but can be preordered for less, check the taxi companies online – a short list is given later, and it is highly advised to use only the official taxies.
COST participants: Please be aware of COST reimbursement restrictions concerning taxi transport!
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By car
The fastest and easiest way to get to Split by car is by using the A1 highway, which is part of international routes E65 and E71. You can also use D1 state road (no tolls, but slower). When you're approaching Split on A1, look for the exit Dugopolje and follow the signs that will direct you to Split. Use GPS to get to the venue, where there is plenty of free parking space (see the map).
By ferry
Split ferry port is the largest passenger port in Croatia. Ferry lines connect Split with the rest of Croatia like Dubrovnik, Rijeka and the islands, as well as with Italy: Ancona (daily) and Pescara. Split ferry port is easily accessible by all kinds of transportation - both the train station and the main bus terminal are located in the port area.
LOCAL BUS TRANSPORT ROUTES
The venue - FESB (Faculty of Electrical Engineering, Mechanical Engineering and Naval Architecture) - is a part of Split university campus and is located at Ruđera Boškovića 32, Split.
Local buses are operated by Promet Split d.o.o.: www.promet-split.hr
Bus tickets are sold by bus driver for 11 HRK, cash in HRK only. Double-ride tickets can be bought in kiosks for 18 HRK, or for 17 HRK if bought in bulk quantity (min. of 5). Tickets are valid for 45 minutes and can be used in any city bus that circulates through the city of Split.
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From downtown to campus (FESB) 1. Use the bus no. 18 or no. 11, either from their first stop HNK, or from the second stop Tržnica (outbound buses are on the west side of the street).
Bus station near Split national theatre (HNK)
West side of Zagrebačka street (Tržnica)
2. Both buses pass by FESB on Matice Hrvatske street. You should exit at the bus stop situated below the pedestrian bridge (5th bus stop counting from Tržnica, or 6th stop counting from HNK). If in doubt, ask for
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“Campus” or “FESB” (if asking locals, don't pronounce FESB as abbreviation, but as a word).
Pedestrian bridge near FESB, the street name is Matice Hrvatske
4. You are now on the south end of the pedestrian bridge, cross it to the north end and you shall see FESB faculty building in the front right direction.
FESB building
From campus (FESB) to downtown 1. From FESB walk back towards the pedestrian bridge, but before crossing it, turn right towards west and find your way down to the bus road (Matice Hrvatske). 2. Walking along the sidewalk, you will find the bus stop 200 m to the west of the bridge.
ENTRANCE
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The bus stop for no. 18 and no. 11 inbound route (from FESB to
downtown) 3. Take the bus no. 18 or no. 11 and exit on Tržnica or HNK (you cannot miss HNK since this is the last stop).
Main bus terminal (airport shuttle) → FESB (and viceversa) (e.g. if you are connecting directly from the airport to FESB, and viceversa)
Walk from the main bus terminal (Autobusni kolodvor Split), in the northbound direction about 450m to Tržnica, where you can take the bus no. 18 or no. 11 in the outbound direction (as described before). Viceversa: coming from FESB by bus, exit at Tržnica and walk 450m to the main bus terminal.
Tržnica
Main bus terminal
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If you want to avoid this walking, you can take the bus no. 2, 9, 10 or 15 for just 1 stop from the main bus terminal to Tržnica, but to catch this bus, you have to walk about 150m in the southbound direction. Viceversa: coming from FESB by bus, exit at Tržnica, cross the street to the west side, and there take the bus no. 2, 9, 10 or 15 for just 1 stop, then walk back about 150m to the main bus terminal.
TAXI SERVICE IN SPLIT
You can find a wide selection of taxi companies, with varying prices, depending also on the way of ordering (on street, online, phone call), but generally very affordable, e.g.:
• Cammeo: 5 kn start, 5 kn per km, https://cammeo.hr/hr/gradovi/split , +385 21 313 313,
• Yellow cab: 5 kn start, 8 kn per km, https://www.zutitaxisplit.com/, +385 21 208 208,
• GoGreen: 9 kn start, 9 kn per km, http://gogreentaxisplit.hr , +385 21 772 772,
• Uber is operational in Split, and you can search online for other companies and pre-ordered transfers.
For your orientation, driving distance from Riva (downtown) to FESB is ca. 4 km, so the ride should cost 4-5 € according to the prices above (as advertised on the web sites). COST participants: Please be aware of COST reimbursement restrictions concerning taxi transport!
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ACCOMMODATION IN SPLIT
EMF-Med does not provide accommodation recommendations or reservations. There is an extensive selection of accommodation on the major booking web sites, such as Booking.com, Hotels.com, Airbnb.com and others. If you need personalized service related to your accommodation, information can be requested from the company GALAXY TRAVEL d.o.o. (www.galaxy-travel.hr) that manages the registrations on behalf of FESB, University of Split. This company is also a travel agency, and can provide accommodation services at a request, as a part of their own everyday business.
COST EMF-MED participants have a special arrangement for accommodation in the campus dorm "Franjo Tuđman" (shown below), which is managed through dedicated communication in the COST Action.
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Map
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CONFERENCE DINNER Wednesday, 12 September at 19:30h, at the Cellars of the Diocletian's Palace (west wing)
Find the Cellars southern entrance situated on Riva (the famous waterfront promenade). Enter from Riva into the Cellars, then immediately turn left and enter to the west wing through the large metal gate.
The Cellars (Podrumi) are a substructure below the Diocletian’s apartment in the southern quarter of the Palace. By converting the palace into the city of Split, most of the residential complex was demolished but the ground floor halls were perfectly preserved. In the early Middle Ages a part of the complex was inhabited, and in one of the halls wine and oil were produced. Today the Cellars are accessible through the Brass Gate of the Palace (from Riva), or through a staircase from the Peristyle. The Western part of the basement has been preserved in its entirety and is almost completely accessible for sightseeing. The Eastern part has collapsed during Middle Age but has been excavated and a large part is also accessible.
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Save the date!
2nd EMF-Med World Conference
& Training School on Biomedical Applications of Electromagnetic Fields
Split, 7-12 September 2020
Contribute to development and optimization of innovative EMF-based medical devices and procedures, which will be safer, more efficient and less invasive!
EMF-Med 2020
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