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Progress in CT

Jim GreenSenior Vice President &General Manager Philips CT

2Medical Systems

3Medical Systems

4Medical Systems

Agenda

• What is CT

• New clinical applications

• CT market

• Why we win

5Medical Systems

What is CT?

• Rotate an X-ray source and detection system around the area of interest

• Transmitted X-rays are received by detection system

• Detection system converts X-Rays to digital data

• Computers reconstruct data into a two dimensional cross-sectional image

• Images are viewed by the doctor who diagnoses the patient

6Medical Systems

CT’s early days

1970’s • Single-slice head scanner• Rotation time in minutes • 10 images (slices) per study

Simple head scan• 10 images• Total scan time: 1 hour

7Medical Systems

CT’s come a long way!

Today• World’s first 4cm large coverage CT• Acquires up to 40 images per rotation• Rotation time in 4/10ths of a second• Sub-millimenter resolution• True volume acquisition• 3-Dimensional viewing

Whole body scan• 3,750 slices• Scan time: 33 seconds

8Medical Systems

Agenda

• What is CT

• New clinical applications

• CT market

• Why we win

9Medical Systems

Top 5 Leading Causes of Death in US

1. Heart disease

2. Cancer

3. Cerebrovascular / Neuro (stroke, etc.)

4. Chronic lower respiratory(COPD, emphysema, etc.)

5. Accidents(auto crashes, etc.)

700,142

553,768

163,538

123,013

101,537

Source: CDC, NCHS, National Vital Statistics System for 2001

29%

23%

7%

5%

4%

Total Number of Deaths: 2,416,425

10Medical Systems

a

a b

b

Coronary angiogram

CT Breakthroughs in Cardiac

CT Coronary Angiogram• In just seconds• Still-frame 3-D picture• Non-interventional• Complete coronary view• Functional Analysis• Cost effective

11Medical Systems

Plaque characterization (in development)

Stent patency

CT Breakthroughs in Cardiac

12Medical Systems

Dr. Charles Fitzgerald, Medical Director, Heart Care Clinic of Arkansas, Little Rock, AK, USA

Cardiac CT

13Medical Systems

CT Breakthroughs in Cancer DetectionFast detection of lung cancer

• 3 second lung scan• Computer aided detection• Easy / fast follow-up

14Medical Systems

CT Breakthroughs in Cancer DiagnosisAccurate, patient-friendly, Virtual Colonoscopy, in seconds..

15Medical Systems

Non Contrast CT CT Perfusion/stroke maps

CT Angiography

CT Breakthroughs in NeurologicDiagnosisComprehensive Stroke Review w/ CT “In minutes, not hours”

16Medical Systems

0102030405060708090

100

1993 1998 2003 2008

Neuro

Guided Proc.Spine

Chest/Thorax

Pelvic/ Abdominal

Cardiac & Vascular

6.6% CAGR6.6% CAGR

CancerDetection

14.5% CAGR14.5% CAGR 14.0% CAGR14.0% CAGR

Pro

cedu

res

in M

Sources: IMV and Philips internal estimates

New Clinical Applications

multi-slice large coverage

CT Procedure Growth in U.S.

17Medical Systems

Agenda

• What is CT

• New clinical applications

• CT market

• Why we win

18Medical Systems

0

500

1000

1500

2000

2500

3000

90 91 92 93 94 95 96 97 98 99 00 01 02 03 04 05 06

Based on common currency (2003 FX rates)EUROS M

Multislice CTIntroduction

Spiral CT Single Slice

Multislice Large

Coverage>16 slice

6% CAGR 1990-2003

Total CT Global Equipment Market History

Sources: Philips internal estimates, NEMA, COCIR, JIRA

19Medical Systems

€ 1,232

€ 316€ 214

€ 101 € 97 € 66

€ 0

€ 200

€ 400

€ 600

€ 800

€ 1,000

€ 1,200

€ 1,400

U.S. Japan China France Germany Italy

Euro M

World Top 6 CT Markets by Size (2003)

Sources: Philips internal estimates, NEMA, COCIR, JIRA

20Medical Systems

Fcst

Fcst

12.7%

13.8%14.2%

16.5%

0

500

1,000

1,500

2,000

2,500

3,000

2001 2002 2003 2004 2005 2006 2007

MAR

KET

EUR

OS

M

0.0%

2.0%

4.0%

6.0%

8.0%

10.0%

12.0%

14.0%

16.0%

18.0%

PH

ILIP

S S

HAR

E %

----

CT Global Orders Market and Philips ShareComments:• ‘03 & ‘04 market decreases

driven by currency• China has excellent growth

opportunity• Strong incremental growth

in Japan• Strong in Europe due to

technology orientation and Philips brand

• NA experienced initial integration issues but is now on track

Projected CAGR 4.1% ’04-’07

21Medical Systems

Agenda

• What is CT

• New clinical applications

• CT market

• Why we win

22Medical Systems

• Royal Philips Research• Technology leader in detection, with large area coverage• Patented Tach technology, more complex than Pentium

Why we win: Technology Leadership

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• Snapshot 3D volume picture• In less than 400msec• Perfect for pediatrics• Most dose efficient

4 cm

4 cm volume segment

22-day-old child

Why we win: Advanced Applications

Technology enables the most advanced applications

24Medical Systems

Why we win: First to Market

History of Firsts to Market • 1980: Solid-state detector

1988: Continuous rotation slip ring CT

• 1991: Multi-slice CT (dual) • 1992: MRC (liquid metal

bearing) X-ray tube• 2002: The First 16-slice CT

First to Market: FDA approved for sale and systems in clinical operation

Today • First with 4cm large coverage

CT (40 slice)• Breakthrough applications:

Neuro & Cardiac• The clear leader in technology

25Medical Systems

Dr. Jonas Rydberg, Associate Professor, Department of Radiology, Indiana University, USA

26Medical Systems

Conclusions

• Backed by Royal Philips Research• Technology drives our costs down, and enables breakthroughs• First-to-market enables our premium pricing• New geographical markets drive our marketshare• Clinical breakthroughs and emerging market segments

are driving our growth

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