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SCIENTIFIC PROGRAMME
27 February 2020, Thursday
Opening Ceremony
14:30 - 14:35 Prof. Dr. Öztekin ALGÜL, Chair, Mersin University
14:35 – 14:40 İkram CENGİZ, President of Turkish Chemists Society
14:40 - 15:00 Zeynep ATABAY, Atabay
15:00 - 15:20 Prof. Dr. İlhan SATMAN, TÜSEB
15:20 – 15:30 Prof. Dr. Ramazan ALTUNDAŞ, Vice President of Turkish
Chemists Society
15:30 - 15:50 Harun KIZILAY, Ph.D., Vice President, Turkish Medicines
and Medical Devices Agency, Minister of Health
15:50 - 16:10 Eray KAPLAN, Vice President, Turkish Medicines and
Medical Devices Agency, Minister of Health
16:10 - 16:40 Prof. Dr. Yusuf BARAN, Rector, IZTECH
16:40 - 17:00 Dr. Hakkı GÜRSÖZ, President, Turkish Medicines and Medical Devices Agency, Ministry of Health
17:00 - 17:30 Coffee Break
1. Session
Session Chair: Prof. Dr. Ramazan ALTUNDAŞ
Opening Lecture
17:30 - 18:10
Prof. Dr. Herve GALONS, Université Paris Descartes “The Changing World of Kinase Inhibitors: Towards Selective Inhibitors”
Award Ceremony
18:10 - 19:00
Prof. Dr. Ramazan ALTUNDAŞ, Gebze Technical University “Turkish Chemists Society 3rd Research Incentive Award Ceremony”
“8th International Drug Chemistry Congress R&D Awards”
19:00 - 20:30
Dinner
28 February 2020, Friday
2. Session
Session Chair: Assoc. Prof. Esen Bellur ATICI
09:00 - 09:40
Dr. Mike WEBB, Independent Consultant, London, UK
“Pharmaceutical Chemical Development - Challenges Over The Last 10 Years”
09:40 - 10:10
Prof. Dr. Ramazan ALTUNDAŞ, Gebze Technical University “A New Approach to The Synthesis of Ibrutinib”
10:10 - 10:30 Prof. Dr. Özdemir DOĞAN, METU “Pyrrolidines, Aziridines and Biological Activity”
WORKSHOPS
Atabay, Odeon Hall
11:00 - 12:00
Doğan TAŞKENT
“Discuss and Determine the Building Blocks of Strategic API Manufacturing In Turkey”
10:30 - 11:00
Coffee Break
3. Session
Session Chair: Prof. Dr. Ali ÇAĞIR
11:00 - 11:40
Prof. Dr. M. Laura BOLOGNESI, University of Bologna
“Multi-Target-Directed Ligand Design Strategy in Alzheimer’s Disease: Lessons Learned and Challenges Ahead”
11:40 - 12:10
Prof. Dr. Erden BANOĞLU, Gazi University
“Discovery of Multitarget Inhibitors in the Arachidonic Acid Pathway by Targeting FLAP/5-LO/mPGES-1 for Intervention with Inflammatory Deregulation”
12:10 - 12:30
Assoc. Prof. Atilla AKDEMİR, Bezmialem Vakıf University
“The Quest for Structurally Novel Lead Compounds Against Breast Cancer”
12:30 - 14:00
Lunch
4. Session
Session Chair: Prof. Dr. Aliye ALTUNDAŞ
14:00 - 14:40
Asst. Prof. Marco PIERONI, Università di Parma “Discovering New Chemotypes That Selectively Inhibit Microbial Carbonic Anhydrases”
14:40 - 15:10
Prof. Dr. Ali ÇAĞIR, IZTECH
“Klavuzons: Multitarget Covalent Inhibitors”
15:10 - 15:30
Assoc. Prof. Dr. Serhan TÜRKYILMAZ, METU “Zinc(II)-Bisdipicolylamine Complex Bearing Agents for Selective Agglutination, Imaging, and Photodynamic Inactivation of Bacterial Cells”
15:30 - 16:00
Coffee Break
WORKSHOPS
Ashland, Odeon Hall
14:00 - 15:30
Enis DEMİR
“Novel Ultra High Speed Film Coating Systems to İncrease Productivity, AquariusTM Genesis” Nadin EKMEKÇİYAN “Binder Selection for Today’s Formulation Challenges”
5. Session
Session Chair: Assoc. Prof. Serhan TÜRKYILMAZ
16:00 - 16:40
Prof. Dr. Orazio NICOLOTTI, University of Bari
“A Similarity-Based Reverse Screening Method to Predict Protein Drug Targets”
16:40 - 17:00
Prof. Dr. Mükerrem Betül YERER, Erciyes University
“Monoclonal Antibodies and Targeted Therapies in Anticancer Drug Discovery”
17:00 - 17:15
Dr. Gökçe YILDIRIM BUHARALIOĞLU, Ege University
“Epigenetic Regulation of Matrix Metalloproteinases in LNCaP Human Prostate Cancer Cell Line”
17:15 - 17:30
Nazlıcan TEZGEL, Abdi Ibrahim Pharmaceuticals
“Stability Studies for Biologics”
6. Session
17:30 - 18:30
Short Oral Presentations
Session Chair Session Chair Session Chair Session Chair
Prof. Dr. Aliye ALTUNDAŞ, Phoenix I Prof. Dr. Nermin Şimşek KUŞ, Phoenix II Prof. Dr. Tijen ÖNKOL, Mirage I-II Prof. Dr. Özlen GÜZEL-AKDEMİR, Odeon
18:30 - 19:30
Dinner
19:30 - 21:30
Poster Presentations, Mirage I-II
29 February 2020, Saturday
7. Session
Session Chair: Prof. Dr. M. Betül YERER
09:00 - 09:40
Dr. Staffan KARLSSON, Astra Zeneca
“Continuous Processing and Real Time Monitoring of Hazardous Chemistry”
09:40 - 10:00
Dr. Yağmur KİRAZ, IZTECH “Overcoming Drug Resistance in Leukemia: A Molecular Approach”
10:00 - 10:15
Dr. Belgin SEVER, Anadolu University
“Design, synthesis and aldose reductase inhibitory activity of new triazole derivatives”
10:15 - 10:30
Asst. Prof. Özlem AKGÜL, Ege University “Inhibition Studies of 2-Aminoethanesulfonic Acid Derivatives Against Some Carbonic Anhydrase Isoforms”
10:30 - 11:00
Coffee Break
WORKSHOPS SEM, Odeon Hall
10:00 - 10:45 11:00 - 11:45
Selim KARACA
“Lyophilization Systems for the Pharmaceutical Industry” Kaan GÜNER
“Data İntegrity Traceability and Security in Pharma”
8. Session
Session Chair: Prof. Dr. Özdemir DOĞAN
11:00 - 11:40
Prof. Dr. Joachim JOSE, Westfälische Wilhelms-University Münster “Bivalent Inhibitors of Human Protein Kinase CK2, an Emerging Target in Cancer”
11:40 - 12:10 Prof. Dr. Süreyya ÖLGEN, Biruni University
“Drug Repurposing in the Development of Anticancer Agents”
12:10 - 12:30
Assoc. Prof. Nurettin MENGEŞ, Van Yuzuncu Yil University “New Types of Imidazole Derivatives and Their Pharmacological Effects on Central Nervous System”
12:30 - 14:00
Lunch
9. Session
Session Chair: Assoc. Prof. M. Dilek ALTINTOP
14:00 - 14:30
Prof. Dr. İlkay ERDOĞAN, Gazi University
“Plant Metabolites at Target in Drug Discovery Process: From Field to Clinic”
14:30 - 15:00
Prof. Dr. Erdal BEDİR, IZTECH
“Developing New Drug Candidates from Triterpenic Sapogenols via Microbial Biotransformation and Semi-synthesis ”
15:00 - 15:30
Assoc. Prof. Serdar SEZER, Süleyman Demirel University “Medical Applications, Pharmacological Properties and Purification of Cannabidiol”
15:30 - 16:00 Coffee Break
WORKSHOPS SEM, Odeon Hall
14:00 - 14:45 15:00 - 15:45
Serdar BİLGESOY “Analysis of 5-Nitrosamines Impurities in Pharmaceutical Products” Halil KIZILARSLAN
“Agilent Raman Spectroscopy Solutions in pharmaceutical QC”
10. Session
Session Chair: Prof. Dr. Erden BANOĞLU
16:00 - 16:40
Assoc. Prof. Antimo GIOIELLO, University of Perugia
“Bile Acids and The Chemistry They Inspire to Discover New Chemical Entities”
16:40 - 17:00
Gökhan BAYRAK, Abdi Ibrahim Pharmaceuticals “Presentation at Case Study of Utilizing DVS in Evaluation of Alternative Source Studies of Active Pharmaceutical Ingredient of a Medicinal Product and Troubleshooting of Observed Differences for Manufacturing Process among the Sources”
17:00 - 17:15 Gürmen KAYNAR, Worldmedicine “From Molecule to Drug; Patent”
17:15 - 17:30
Asst. Prof. Burçin TÜRKMENOĞLU, Erzincan Binali Yildirim University “4D-QSAR and Molecular Docking Studies on Some Steroidal Derivatives”
17:30 - 17:45
Prof. Dr. Şeniz ÖZALP YAMAN, Atılım University “New DNA Targeted Antitumor Agents of Platinum and Copper”
17:45 - 18:00
Asst. Prof. Safacan KOLEMEN, Koç University
“Cancer Cell Selective Photodynamic Therapy Agents”
18:00 - 18:15
Kübra Demir YAZICI, İstanbul University
“Inhibition of the α-class Carbonic Anhydrase from Vibrio cholera(VchCA) with Novel Sulfonamido based Hydrozones”
18:15 - 18:30
Dr. Serkan DAYAN, Erciyes University
“Microwave-Assisted Rapidly Hydroxyapatite Fabrication in Natural Media and Investigation of Drug-Carrying Capacity”
18:30 - 18:45
Ece PEMBECİOĞLU, Vefa İlaç
“Traditional and herbal medicinal products and industry approach”
Career Talk 2020 SEM, Mirage Hall
18:45 - 19:45
Zafer KARKAÇ, LSC Group Manager
18:45 - 19:30
Dinner
19:30 - 21:30
Poster Presentations, Mirage I-II
01 March 2020, Sunday
11. Session
Session Chair: Prof. Dr. Hamdullah KILIÇ
09:00 - 09:40
Sandro O. LAISO, Intertek
“Analytical Approaches for Reliable Screening and Control of Genotoxic İmpurities”
09:40 - 10:00
Prof. Dr. Ahmet C. GÖREN, Bezmialem Vakıf University “Reliability and Validity of Dietary Supplements”
10:00 - 10:15
Dr. Sıtkı Doğa ELÇİ, LumiLabs “Investigation of The Activation Mechanisms of Natural Clotting Processes by Highly Deacetylated Chitosan”
10:15 - 10:30
Therese TRAN, Kromasil “Investigation of Impurity Profiles in Preparative HPLC Applications of Peptide APIs”
10:30 - 11:00
Coffee Break
12. Session
Session Chair: Dr. O. Mutlu TOPAL
11:00 - 11:40 Dr. Lance SMALLSHAW, UCB S.A., Wallonia, Belgium
11:40 - 12:00
Gül Gönül KAYAR, Abdi Ibrahim Pharmaceuticals “In Vitro Comparative Nasogastric (NG) Tube Study for Film Coated Tablets Containing Platelet Aggregation Inhibitor”
12:00 - 12:15 Asst. Prof. İrem KULU, Gebze Technical University “Bioorthogonal Nanozymes: Synthesis and Kinetic”
12:15 - 12:30
Büşra CESUR, Akdeniz University “Preparation and Safety Evaluation of Nano-niosomes for Biotechnology-derived Medicinal Products and Cosmetics”
12:30 - 14:00
Lunch
13. Session
Session Chair: Assoc. Prof. Dr. Nurettin MENGEŞ
14:00 - 14:15
Assoc. Prof. Salih ÖZÇUBUKÇU, METU “Simple Amino Acid Based Low Molecular Weight Organogel as Drug Delivery Systems”
14:15 - 14:30
Asst. Prof. Süleyman AKOCAK, Adiyaman University “Potent and Selective Inhibition of Carbonic Anhydrase Isoforms by Using 1,3,5-triazine and 1,3-diaryltriazene Substituted Sulfonamides”
14:30 - 14:45
Dr. İlke Uğur MARION, METU “Problem Specific Computational Chemistry Solutions in Drug Design”
14:45 - 15:00
Dr. Burcu BİNİCİ, TUBİTAK National Metrology Institute
“Production of Certified Reference Material for The Measurement of Aminoacids And Neurotoxic Aminoacids in Lentil”
15:00 - 15:15
Ömer SONKAYA, Aksaray University “Design and Synthesis of a Novel NIR Dye”
15:15 - 15:30
Muhammed TRAWALLY, İstanbul University
“Synthesis and Inhibitory Activity of 2-(Alkylidene/arylidene)-N-(2-(non)substituted-3/4-sulfamolylphenyl) Hydrazine Carbothioamide derivatives as Tumor-associated Carbonic Anhydrase hCA IX and hCA XII Inhibitors”
15:30 - 15:45
Zinnet Şevval AKSOYALP, Akdeniz University “Effects of Vorapaxar Incubation on Human Left Internal Mammary Artery Endothelial Function”
15:45 - 16:30
Closing Ceremony and Poster awards
Your poster will be tacked to a 100 cm (tall) x 70 cm (wide) board so therefore should not exceed the measurement of the board. Your poster should be placed at the poster board with number corresponding to the conference agenda and available for viewing by attendees througout the conference. Authors are expected to be present at their poster during the poster session on Friday and Saturday at 7:30 pm. Poster awards will be given at the closing ceremony.
ORAL PRESENTATION PROGRAMME
Presentation Hall: Phoenix I
POSTER NO Author Title
OP1 Hatice BEKÇİ The Effect of Sistein Carbon Dots on Cell Survival of A549 and Beas-2b Cell Lines
OP3 Gizem DİNLER DOĞANAY Phosphorylation dependent interaction of pro-survival Bag-1 isoforms with MAPkinases
OP4 Jale YILDIZ Identification of the Recurrent VUSs in CHEK2 Gene in Breast Cancer Patients
OP6 Zeliha Nur YILMAZ In silico Molecular Docking, ADME and Druglikeness Properties of Aromatic Schiff Bases
OP8 Gozde YENİCE CAKMAK Synthesis, and Molecular Docking Studies of Some Novel Benzothiazoles as HDAC Inhibitors
OP9 Sergen GÜL Catalyst-free and green chemistry approach for unknown fused tetraheterocyclic skeleton
OP10 Beyza SIMSEK Synthesis and Evaluation of In vitro Antiproliferative Activity of Some Bisbenzazol Derivatives as Topoisomerase Enzyme Inhibitors
OP11 Serdal KAYA A New Strategy for the Synthesis of Beta- and Gamma-Carbolines
OP12 Dilek AKBASLAR Synthesis and Evaluation of Antimicrobial Properties of Some Indolyl Chalcone Derivatives
OP13 Dilek AKBASLAR Synthesis of Tetrasubstituted Pyrroles and Pyrrole-Based Chalcones and Investigation of Their Cytotoxic Effects on MCF-7 Cell Line
OP14 Havva KURT An Investigation For New Topical Antiseptic Solution with Unknown Agents
OP15 Yakup BUDAK Synthesis, characterization of hydroxyapatite and comparison with commercial hydroxyapatite sample
OP16 Yakup BUDAK Anti-fungal activities of Marrubium vulgare L. different solvent extracts against plant pathogenic fungi
OP17 Nebih LOLAK 1,3,5-Triazin Türevi Üreido Benzen Sülfonamitlerin Sentezi, Antioksidan, Asetilkolinesteraz, Bütirilkolinesteraz ve Tirozinaz Enzim Aktivitelerinin Araştırılması
OP18 Karina I S AMUDİ New Synthetic Route For Pyrazolo[1,5-a]pyrazine-2-carbohydrazide Derivative
OP19 Büşra ÖZTÜRK AYDIN Synthesis Of N-Alkylated Pyrazolo[3,4-d]pyrimidin Derivatives
OP20 İrfan KOCA Experimental and theoretical characterization and molecular docking studies of novel sulfonamide derivatives
OP21 Gizem Tuğçe ULU The Challenges of Drug Application in Targeted Cancer Treatment and Differentiation of Cell Morphology
OP22 Fatma ALBAYRAK Synthesis of Maleimide-Based Heterocyclic Molecules and Investigation of Their Anti-Cancer Activities
OP23 Ömer Tahir GUNKARA Synthesis of Substituted Bis(heteroaryl)maleimide Derivatives as Glycogen Synthase Kinase-3β Inhibitors With Potential Role as Anticancer Agents
OP24 Yaren CABBUR Synthesis of bicyclic aldehyde derivatives from quasi favorskii reaction; Investigation of their antioxidant activities
Presentation Hall: Phoenix II
POSTER NO Author Title
OP25 Aişe ÜNLÜ Antimicrobial Effect of Green Synthesis of Silver Nanoparticles Using Pomegranate Peel Extract
OP26 Burak KUZU Design and Synthesis of Novel 4-Methylaminopiperidine-Substituted Imidazopiridine Derivatives and Investigation of Their Antimicrobial Activities
OP27 Burak KUZU Design and Synthesis of Novel Diisopropyloxalamide Derivatives and Their Docking Studies for COX Inhibitions
OP28 Osman Nuri ASLAN Synthesis and anticancer activity of novel urea derivatives
OP29 Osman Nuri ASLAN Synthesıs, Characterızatıon And Investıgatıon Of Bıoactıve Propertıes Of Urea Based New Hybrıd Molecules
OP30 Mesut ŞENTÜRK Cytotoxic and Antiproliferative Activity of N- (4-Chlorophenyl) -1 H-Indole-2-Carboxamide on Prostate and Osteosarcoma Cell Lines.
OP31 Saffet ÇELİK Determination 42 Amino Acids in Royal Jelly from Different Regions of Turkey
OP32 Bunyamin OZGERİS Synthesis of Some Carbamates From Substituted Phenethylamines
OP33 Mustafa Kemal GÜMÜŞ 1,3-nükleofil olarak 3-amino-1,2,4-triazol’ün modifiye Biginelli reaksiyonları
OP34 Zekiye Şeyma SEVİNÇLİ Design, Synthesis And In Vitro Applications Of New Types Of Cell Imaging Agents: Imidazopyridine Skeleton
OP35 Burçin TÜRKMENOĞLU Synthesis of Heterocyclic Compounds and 4D-QSAR Study
OP36 Zehra ÖKSÜZ Evaluation of Reverse Transcriptase Inhibitor Nucleoside Analogue Resistance Profile in HBV Patients with HCMV/EBV Coinfection
OP37 Ufuk ATMACA A Safe Alternative for The Synthesis of Primary Carbamates From Alcohols
OP38 Hamdi ÖZKAN 1-(2-(5-(4-Sübstitüefenil)-1H-tetrazol-1-il)etil)amin Bileşiklerinin Sentezi Karakterizasyonu ve Biyolojik Özelliklerinin Araştırılması
OP39 Ali Enis SADAK Live Cell Imaging
OP40 Özge ÇAĞLAR Activity and stability enhancement by chemical modification of the Candida rugosa Lipase
OP41 Elif ÖZYİLMAZ Immobilization of Candida rugosa lipase on Calix[4]aren functionalized water-soluble iron oxide magnetite nanoparticles for enzymatic resolution of (R,S)-Naproxen methyl ester
OP42 Murat KIRANŞAN Removal of Antibiotic Drug Wastes from Aqueous Solutions by Photocatalytic Ozonation Process
OP43 Murat KIRANŞAN A review on the Removal of Pharmaceutical Wastes from Aqueous Solutions under the Effect of Different Nanocomposite Catalysts of Sonocatalytic Degradation
OP44 Mehmet KUZUCU Synergistic Anti-proliferative and Anti-Cancer Effects of Gambogic Acid with Capecitabine in MDA-MB-453 Human Breast Cancer Cells
OP45 Alim SUSAM Towards a multi-emissive drug
OP46 Arzu GÖBEK Synthesis of Flouro-Substituted Bis-Chalcone Derivatives as an Antiproliferative Agent
Presentation Hall: Mirage I-II
POSTER NO Author Title
OP47 Mehmet OGUZ The Synthesis of Cationic Calix[4]arene Derivatives and Evaluation of Their Cytotoxic Potential for Human Cancerous Cells
OP48 Mehmet ERŞATIR Novel Coumarin-Selenophene Hybrids as Potential Antiproliferative Agents: Synthesis and Biological Evaluation
OP49 Özgür YILMAZ α-C-H cyanation of tertiary amines with a new method
OP50 Erdin DALKILIÇ Synthesis of Novel Molecular Clip Based on Norbornadiene Framework
OP51 Bilal NİŞANCI
Transition Metal Nanoparticles Supported on Metallic Aluminum Nanoparticles Intercalated Two-Dimensional Carbon Support Materials as Catalysts for the New Generation of Transfer Hydrogenation Reactions
OP52 Bilal NİŞANCI A Facile and Highly Efficient Dehalogenation of Halides Catalyzed by Palladium Nanoparticles Supported on Mesoporous Graphitic Carbon Nitride
OP53 Yusuf AKBABA Synthesis of Novel Symmetrical Sulfamides Derived 2-Aminotetralins
OP54 Sinem ÜMİT Synthesis of bicyclic haloalcohols from ketene addition reaction; Investigation of their antioxidant activities
OP55 İrfan ÇAPAN Synthesis of Potential Biologically Active Molecules; Thiosemicarbazide and 1,2,4-Triazole Derivatives Having the Carbazole Hybrid.
OP56 Gönül YAPAR Based Imine Compounds
OP57 Gönül YAPAR Synthesis of New Bis-Schiff Base Podands and Investigation of Their Antioxidant Activity, Biological and Anion Sensor Properties
OP58 Nalan İmamoğlu The Contrast Effects of Pre- and Post- Treatment with Dexamethasone on the Expressions of Interleukin (IL)-6, IL-8 and Eotaxin-1 in Lipopolysaccharide-Stimulated BEAS-2B Cells
OP59 Onur DEMİRKOL Extraction of Furanocoumarin and Coumarins by Subcritical Water Extraction from Ruta chalepensis
OP60 Sinan BİLGİNER Synthesis, Cholinesterase Inhibition and Molecular Docking Studies of Novel Mannich Bases of Banzoxazolone Chalcone Compounds
OP61 Burak ARABACI Determination of Sapropterin Dihydrochloride in Solid Dosage Forms by Visible Spectroscopy
OP62 Aysun DEGIRMENCI Polymer Drug Conjugates for Pancreatic Cancer Therapy
OP63 Enfal ÖZER Antibody-Drug Conjugates As Targeted Drug Delivery Agents
OP64 Ümit BABACAN Variations of Ferulic Acid in Traditional Turkish Wheat Species
OP65 Ümit BABACAN Cell Viability Effects of Ferulic Acid on Melanoma Cell Line (SK-MEL-30)
OP66 Ümit BABACAN A Sensitive Determination of Cannabidiol (CBD) by HPLC
OP67 İrem NAMLI An Approach for Solubility Enhancement of Poorly Water-Soluble Drug Cefdinir with Polyvinyl Alcohol
OP68 Ülkü ÇAYKÖYLÜ A Review of Quantum Dot Based Nano-Biosensors
Presentation Hall: Mirage I-II
POSTER NO Author Title
OP69 Salli GÜR Antibody Polymer-Drug Conjugates As Targeted Chemotherapy Agents
OP70 Erbay KALAY Palladium Nanoparticles Assembled on Mesoporous Graphitic Carbon Nitride: A Highly Efficient Heterogeneous Catalyst for the Stille Coupling Reaction
OP71 Malak ALIZADA The Synthesis of Calixarene Based Non-Toxic Fluorogenic and Colorimetric Dual-Channel Chemo-sensor and its Applications in Bioimaging
OP72 Meltem TAN Novel Synthesis Method For 5,6-Substitue Heterobicyclic Compounds
OP73 Meltem TAŞ Anadolu Kestane ve Narenciye Ballarının Glisemik İndeksleri
OP74 Begüm Hazar ÇİFTÇİ Liquidambar orientalis reçinesinin üreaz enzim inhibisyon aktivitesi
OP75 Göksun DEMIREL Metamfetamin Bağımlılığın Tedavisinde Terapötik Aday :mikroRNA- Let7b-3p
OP76 Mine BUĞA Synthesis of Benzimidazole-2-Phenyl with Alkyl / Alkyloxy linker Derivatives and Their Investigation of Antiproliferative Effect
OP77 E. Vildan BURGAZ Yeni 7,11-diaril-3-tiyookso-2,4-diazaspiro[5,5]undekan-1,5,9-trion Bileşiklerinin Sentezi
OP78 Pelin VURAL Selectıng “Worst Case” For Equıpment Cleanıng Valıdatıon
OP79 Efe Doğukan DINCEL Novel 4-thiazolidinones and 1,3,4-oxadiazoles: Synthesis, theoretical evaluation of ADME properties and docking study
OP80 Ersin DEMIR The electrochemical behaviour and determination of bupivacaine ophthalmic drug by square wave voltammetry on glassy carbon electrode
OP81 Emre ÜNLÜ Determination of anthrax by strong luminescence of lanthanide phosphorescence
OP82 Şeyma OCAKÇI Design and synthesis of a new chemiluminogenic probe for hypochlorite
OP83 M. Fatih POLAT Design, Synthesis and Determination of Bisbenzazol Derivatives for Antiproliferative and Antimicrobial Activity
OP84 Tansu DOĞAN Development of Practical Electrochemical System for Phenytoin Detection
OP85 Tansu DOĞAN
Preparation and Characterization of Metal Oxide Nanoparticles Modified Carbon Nanotube-Conducting Polymers Based Composite Electrode For Simultaneous Determination Of Melatonin And Caffeine
OP86 Nilgun KARASU Effect Of Tamoxifen-Gambogic Acid Combinations on Antiproliferative Activity in Estrogen Receptor-Positive Breast Cancer Cells
OP87 Eren BOSTANCI Investigation of the Effects of BK369 Compound on Breast Cancer
OP88 Yakup KAPTAN Synthesis of 3,5-Diarylsubstituted İsoxazoles as an Anticancer Agent
OP89 Derya AKTAŞ ANIL Synthesis and Investigation of Anticancer Properties Fluoro Substitued Bis-Chalcone Derivatives
OP90 Derya AKTAŞ ANIL Elucidation of Chemical Structures of Some Chalcones Compounds by NMR Spectroscopy
POSTER PRESENTATION PROGRAMME
Poster No
Author
Title
P2 Hatice BEKÇİ The Effect of Pt-Au Bimetalic nanoparticules of Curcuma Longa extract Cell Survival of A549 and Beas-2b Cell Lines
P5
Gizem DİNLER DOĞANAY Development of a Practical Capillary Zone Electrophoresis Method to Determine Charge Variant Profiles Under Forced Degradation Conditions for Monoclonal Antibodies
P7
Zeliha Nur YILMAZ Investigation of Functional Models for the Catalase, Catecholase and Phenoxazinone Synthase Enzymatic Activities
P91 Muhammed TUNEĞ Aromatik Yapıya Sahip Bis-Sülfonamit Schiff Bazı Türevlerinin Sentezi, Antioksidan, Asetilkolinesteraz ve Bütirilkolinesteraz Aktivitelerinin Araştırılması
P92 Eylem Esin YÜCESOY Astım İlaç Etken Maddesi Olan Tomelukast’ın Benzer Bileşiklerinin Sentezi ve Yapılarının Aydınlatılması
P93 Burçin KIVANÇ Comparison of Sink Condition Solubility Studies of A Direct Factor Xa Inhibitor Molecule By Traditional Solubility Methodology And Compendial Apparatus
P94 Yonca TARAMAN Artvin Yöresinde Yetişen Bazı Yenilebilir Mantarların Metal Konsantrasyonu ve Toplam Fenolik İçeriğinin Belirlenmesi
P95 Canan ALTUNTAŞ Yeni triazol-salisiliden Schiff bazı türevlerinin çevreye duyarlı sentezi ve yapılarının aydınlatılması
P96 Elif Tuğçe ERDEVE Molecular modelling studies to identify novel inhibitors of the human 26S proteasome complex
P97 Özlen GÜZEL AKDEMİR The Ongoing Quest for Selective hCA IX/XII Inhibitors
P98 Serenay AKYOL Development of a Reversed Phase UHPLC Method As an Alternative of Normal Phase HPLC Method For Vitamin D3 (Cholecalciferol) 50000 IU/15 ml Oral Drop Assay Analysis
P99 Handenur YILMAZ The One Pot Synthesis and Antioxidant Activity Determination of Novel Benzothiazine Derivatives
P100 Nursena MUTLU Yeni Benzoksazin Türevlerinin Sentezi ve Antibakteriyel Etkilerinin Araştırılması
P101 Gülnur DANDİN Synthesis and Antibacterial Activity of New Sulfonamide Derivatives Containing Thiazolidine Ring
P102 Belma ZENGİN KURT Synthesis and Cytotoxic Activity of Novel Flurbiprofen Derivatives Containing Urea Group
P103 Belma ZENGİN KURT Synthesis and Cytotoxic Activity of New Sorafenib / Ruthenium Complexes
P104 Suray JUMAMYRADOVA The One-Pot Synthesis and DNA- Interaction of Novel Benzoxazine Derivative.
P105 Gulsah AYDİN Use of Lecithin as Emulsifier in Herbal Cream Production
P106 Sümeyye TURANLI Synthesis of New Vicinal Diaryl Five-Membered Heterocyclic Compounds with Potential Anticancer Activity
P107 Gökçe UZUNAY The search for novel inhibitors of the human 26S proteasome complex
P108 Ali DİŞLİ Bazı Tiyotetrazol Türevi Bileşiklerin Antimikrobiyal Aktivitelerinin Belirlenmesi
P109 Emre ÖZCANLAR Method Validation of Establishing the Sterilization Dose in Gamma Sterilization Process for Medical Device (Class III)
P110 Gülnur ARSLAN Synthesis of 3-Substitued-5-Chloro-2-(3H)-Benzothiazolone Derivatives
P111 Demet CANSARAN DUMAN The Comparison of miRNAs That Respond to Anti-Breast Cancer Drugs and Usnic Acid For The Treatment of Breast Cancer
P112 Demet CANSARAN DUMAN The role of usnic acid in regulating apoptosis of SKBR-3 breast cancer cell
P113 Ayca DEDEOGLU Novel 3,5-Disubstituted-1,3,4-Oxadizoles: Synthesis, Anti-inflammatory Activity and Enzyme Interactions
P114 Duygu YALÇINKAYA YAVUZ Development of a Practical Capillary Zone Electrophoresis Method to Determine Charge Variant Profiles Under Forced Degradation Conditions for Monoclonal Antibodies
P115 Seminay GÜLER Real Time Kinetic Analysis of Biosimilar Drugs Based on Surface Plasmon Resonance (SPR)
P116 Sultan ÇETİN Development of Glutathione Selective Silicon-Fluorescein Based Photodynamic Therapy Agents
P117 Ali Osman SARIKAYA Stabilization of Cyclic Lipopeptide Antibiotic Powder for IV Injection with the Lyophilization Process
P118 Ulvi MEHDİZADE Determination of roflumilast by a new HPLC metho
P119 Ebru İLHAN LALE Yumuşak Kapsül Formlu Ürünlerin Çözünme Testi Analizinde Oluşabilecek Çapraz Bağlanma Problemine Çözüm Yaklaşımları
P120 Filiz ÇALIK Dendron−Polymer Conjugate Based Cross-Linked Micelles: A Versatile Nano Carrier for Targeted Delivery
P121 Toghrul ALMAMMADOV Resorufin Dye in Photodynamic Therapy: An Enzyme Activatable Photosensitizer for Selective Cytotoxicity
P122 Burak ÇOBAN A Novel Benzimidazole-Benzothiadiazole Derivative: Synthesis, Characterization, DNA Interaction and Cytotoxic Activity Studies
P123 Gizem KURŞUNLUOĞLU Terapötik Monoklonal Antikorların Analitik Karakterizasyonu
P124 Elçin ÇAĞATAY Synthesis and Characterization of Murryaquinone-A Derivatives and Determination of Their Biological Activity
P125 Oğuz ERDOĞAN Design of potential inhibitors of mTOR using molecular modelling studies
P126 Oğuz ERDOĞAN Evaluation of Metabolites Produced by Fungal Biotransformation of Apigenin and Fisetin and Their Cytotoxic Activities
P127 Sevil İRİŞLİ Antikanser Aktiviteye Sahip Yeni Pt(II)-Benzimidazol Kompleksleri
P128 Ahmet Fatih ŞAHİN Designing Potential hIKK2 Inhibitors Using Molecular Modelling Studies
P129 Ahmet ÖZDEMİR Synthesis, In vitro and In silico Evaluation of A Series of Pyrazolines as New DPP-4 Inhibitors
P130 Hasan SOYBİR New Pyrazole-Based Thiosemicarbazone Derivatives as Anti-Breast Cancer Agents
P131 Kübra ORAL Determination of Anticolorectal Cancer Effects of New Imidazole-Based Thiazolyl Hydrazone Derivatives
P132 Mustafa OZTURK The Therapeutic Potential of C-Pycocyanin for Acute Lymphoblastic Leukaemia Cells
P133 Gülsen Deniz KAHRAMAN Kazdağları Esintili Krem
P134 Selingün ÇAKIR Biyoaktivite Potansiyeli Olan Yeni Amino Tiyofenlerin Sentezi ve Yapılarının Aydınlatılması
P135 Gülay BULUT Combination Treatment with YK-4-279 Enhances Cisplatin Chemosensitivity in A549 Non-Small Cell Lung Cancer Cell Line Through Alteration of EGFR-STAT3 Signaling Pathway
P136 Ömer AVŞAR Unraveling the Molecular Requirements of Selective Recognition of Antigen A by its Antibody Using Molecular Modelling Studies
P137 Hande GUNDUZ Hemicyanine Based Phototheranostic Agents for Cancer Imaging and Therapy
P138 Nursefa Zengin The use of BINAP.PdCl2 as a homogeneous catalyst for the reduction of nitroaren in aqueous medium
P139 Remzi Burak ÖZTÜRK Design, Synthesis and Evaluation of A New Series of Tetrazole-Hydrazone Hybrids as Potential Cytotoxic Agents on PC-12 Cells
P140 Ecem KUZPINAR In Vitro Diffusion Test Study Using Franz Diffusion Cell System for a Non-Steroidal Anti-Inflammatory Prodrug Ophthalmic Suspension
P141 Mehmet GÜMÜŞ The Synthesis and Characterization of Potential Anticancer Agents Bearing Pyrazole and Benzo Diazepine Heterocyclic Structures
P142 Mehlika Dilek Altıntop A New Series of Thiazole-Based ABL1 Kinase Inhibitors as Antitumor Agents against Chronic Myelogenous Leukemia
P143 Aykut DEMİRKIRAN Structural Characterization of Monoclonal Antibody by ESI-Q-TOF
P144 Nur Hilal OLGUN Molecular Docking Studies of Some Strigolactone Analogous as Cdk5 Inhibitors: Potential Lead Evaluation Related to Tau Hyperphosphorylation in Alzheimer Disease
P145 Tuğçe TUĞLU YENİGÜN Effects of Formulation Parameters on the Release of Metformine From Encapsulated Microparticles
P146 Enis IŞIK Stable NanoEmulsion Production And Optimization Of Droplet Size Distribution
P147 Merve ÇITAK Quality by Design Approach for Analytical Method Development in Liquid Chromatography with Drug Product Containing Nicotine Receptor Antagonist
P148 Erez UZUNER Determination of Effects of Nilotinib and SK-1 II on Human Telomerase Reverse Transcriptase (hTERT) in Acute Lymphoblastic Leukemia Cells
P149 Amani AMAMRA Antimicrobial activity and total phenolic content of aqueous extract of Amaranthaceae
P150 Polen YUNUS Possible Use of Nilotinib Against HER2+ Breast Cancer Cells
P151 Aliye ALAYLI ALTUNDAŞ M. Tuberculosise Karşı Antimikrobakteriyal Etki Gösterebilecek (1-Benzil-1H-1,2,3-triazol-4-il)(furan-2-il)metanonların Sentezi
P152 Güler YAĞIZ (1-Benzil-1H-1,2,3-Triazol-4-il)(Fenil)Metanon Türevlerinin Sentezi ve Mycobacterium Tuberculosis Basili Üzerine Etkilerinin İncelenmesi
P153 Nalan YILMAZ Synthesis and Evaluation of A Series of Thiazole Derivatives as New Apoptotic Anticandidal Agents
P154 M. Mustafa SÜNGÜ Comparison of Tetrazolium (MTT) and Sulforhodamine B (SRB) Protein Assays for Assessing in vitro Cell Viability
P155 Anisa AZIMI Preparation of the Inclusion Complexes of Water Soluble Calix[4,8]arene L- Proline Drtivatives and Quercetin: Solubility, Cytotoxic effect
P156 Handan SEZEN Anjiyotensin Dönüştürücü Enzim Inhibitörleri Ve Kalsiyum Kanal Blokerleri Kombinasyonu Prosesinde İkili Etkin Madde Uyumsuzluğunun Giderilmesine Yönelik Proses Optimizasyonu
P157 Murat VARDAR Development of A Parenteral Nutrıtıon Product Wıth an Optımızed and Sustaınable Productıon Technıque by Qbd (Qualıty By Desıgn)
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Laboratuar ve Plot boy Süperkritik Akışkan Ekstraksiyon sistemleri (SFE) ve
Aksesuarları, Katı Faz Ekstraksiyonu (SPE) kartuş ve plakaları, Burst
sistemleri, QuEChERS, Yağ-gres filtreleri ...
İlaç sentez, saflaştırma ve ekstraksiyon, Aerojel kurutma, Tekstil, Esansiyel
Yağ, Implant temizliği, Nanopartikül Üretimi, Polimer, Gıda……..uygulamaları
Rutin ve Araştırma Laboratuarları için değişik özellik ve boyutlarda Glove Box
ve aksesuarları, PCR Kabini, Desikatör, Vakum Kabinleri, Hücre Kültürü
Kabinleri, .....
Sertifikalı Standart Referans Maddeler (Gıda, Çevre, Klinik, Endüstriyel
uygulamalar için), Farmasotik ve doğal ürün standartları, Sertifikalı Organik
ve İnorganik Standartlar, Yüksek saflıkta Metal, Tuz ve Oksitler,
Organometalik Standartlar, Yeterlilik test standartları (Proficiency Test),
…….
Her tür reaksiyon için kullanımı kolay ve pratik; Otomatik veya Manuel Kontrollü Kesikli
reaktörleri, Akış Rektörleri, Büyük Kapasiteli Reaksiyon Sistemleri (Plot), Reaksiyon
Kalorimetresi ile;
“ İlaç keşfi ve gelişimi, Kristalizasyon, Polimerizasyon ve Nanopartikül Sentezleri “
için VERİMLİLİĞİ YÜKSEK, HIZLI VE SENTEZLENMESİ ZOR REAKSİYONLARI
gerçekleştirecek çözümler sunar.
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