treating & beating anxiety and depression with nutritional therapy rodger h. murphree, d.c.,...

Treating & Beating Anxiety and Depression

with Nutritional Therapy

Rodger H. Murphree, D.C., C.N.S.

www.TreatingAndBeating.com

Treating & Beating Anxiety and Depression

with Nutritional Therapy

Rodger H. Murphree, D.C., C.N.S.

www.TreatingAndBeating.com

In any given 1-year period,9.5 percent of the population,

or about 18.8 million Americanadults, suffer from depression.

In any given 1-year period,9.5 percent of the population,

or about 18.8 million Americanadults, suffer from depression.

One in three doctor visits by women now involve a

prescription for an antidepressant medication.

One in three doctor visits by women now involve a

prescription for an antidepressant medication.

And one in ten American womentake at least one antidepressant drug.

Americans now spend more money on antidepressants than the Gross National

Product of two-thirds of the world’s countries.

And one in ten American womentake at least one antidepressant drug.

Americans now spend more money on antidepressants than the Gross National

Product of two-thirds of the world’s countries.

The indirect and direct costs of mood disorder illnesses totals over 43 billion dollars a year.

The indirect and direct costs of mood disorder illnesses totals over 43 billion dollars a year.

As many as 10% of the U.S. population has taken one of these

medications. Prescription antidepressants sales reached a total of 37 billion in sales in 2003, which

came out to $9 million more than was spent on treatments for the heart,

arteries and blood pressure.

As many as 10% of the U.S. population has taken one of these

medications. Prescription antidepressants sales reached a total of 37 billion in sales in 2003, which

came out to $9 million more than was spent on treatments for the heart,

arteries and blood pressure.

It All Started With the PillNew York magazine called a

“wonder drug.”

The March 1990 issue of Newsweek had a picture on it

its cover.

It All Started With the PillNew York magazine called a

“wonder drug.”

The March 1990 issue of Newsweek had a picture on it

its cover.

By 1994 Prozac had become the fastest

growing prescription drug in America, with sales

over $1.2 billion.

By 1994 Prozac had become the fastest

growing prescription drug in America, with sales

over $1.2 billion.

Two other selective serotonin re-uptake inhibiting (SSRI)

drugs had almost equal sales. In 1998 these three SSRI drugs: Prozac, Paxil and

Zoloft accounted for over $4 billion in annual sales.

Two other selective serotonin re-uptake inhibiting (SSRI)

drugs had almost equal sales. In 1998 these three SSRI drugs: Prozac, Paxil and

Zoloft accounted for over $4 billion in annual sales.

Sales continued to climb, reaching 37

billion in 2003

Sales continued to climb, reaching 37

billion in 2003

Alarmingly, the largest growth spurt in antidepressant use has been among preschoolers, ages 2-4.

In 2003 over one million American children were taking an antidepressant medication.

Alarmingly, the largest growth spurt in antidepressant use has been among preschoolers, ages 2-4.

In 2003 over one million American children were taking an antidepressant medication.

This is alarming since FDA has warned that: Suicide occurs more than twice as much on antidepressants than on sugar pills in individuals under age 25.

This is alarming since FDA has warned that: Suicide occurs more than twice as much on antidepressants than on sugar pills in individuals under age 25.

This statistic is even more scandalous when you learn that Eli Lilly knew from their earliest trials in 1985 that Prozac increased the risk of suicide by as much as 12 to 1 over placebo or older antidepressants.

This statistic is even more scandalous when you learn that Eli Lilly knew from their earliest trials in 1985 that Prozac increased the risk of suicide by as much as 12 to 1 over placebo or older antidepressants.

And doesn’t work in adolescents.Courtroom documents reveal this little gem from Glaxo Smith Kline “Essentially, the study (concerning Paxil) did not really show it was effective in treating adolescent depression, which not something we want to publicize.”

And doesn’t work in adolescents.Courtroom documents reveal this little gem from Glaxo Smith Kline “Essentially, the study (concerning Paxil) did not really show it was effective in treating adolescent depression, which not something we want to publicize.”

All this fuss over a drug the FDA approved, based on 3 studies involving 286 patients over a period of 6 weeks. Of the original 14 studies, only 3 proved Prozac, was more effective than placebo or an older antidepressant.

All this fuss over a drug the FDA approved, based on 3 studies involving 286 patients over a period of 6 weeks. Of the original 14 studies, only 3 proved Prozac, was more effective than placebo or an older antidepressant.

Selective Serotonin Re-uptake Inhibitor (SSRI) Medications:

In almost half of the studies show that up to 70% of those taking SSRI antidepressant medications do just as well by taking a placebo or sugar pill.

Selective Serotonin Re-uptake Inhibitor (SSRI) Medications:

In almost half of the studies show that up to 70% of those taking SSRI antidepressant medications do just as well by taking a placebo or sugar pill.

Individuals on SSRI drugs increased their Hamilton Rating Scale 2 points compared to those on placebo.

Individuals on SSRI drugs increased their Hamilton Rating Scale 2 points compared to those on placebo.

All of The Following Drugs Have Potential and Common Side effects...

All of The Following Drugs Have Potential and Common Side effects...

anxiety, depression, headache, muscle pain, chest pain, nervousness, sleeplessness, drowsiness, weakness, changes in sex drive, tremors, dry mouth, irritated stomach, loss of appetite, dizziness...

anxiety, depression, headache, muscle pain, chest pain, nervousness, sleeplessness, drowsiness, weakness, changes in sex drive, tremors, dry mouth, irritated stomach, loss of appetite, dizziness...

nausea, rash, itching, weight gain, diarrhea, impotence, hair loss, dry skin, chest pain, bronchitis, abnormal heart beat, twitching, anemia, low blood sugar, and low thyroid.

• Deplete melatonin levels.• Tricyclic antidepressants deplete CoQ10.

nausea, rash, itching, weight gain, diarrhea, impotence, hair loss, dry skin, chest pain, bronchitis, abnormal heart beat, twitching, anemia, low blood sugar, and low thyroid.

• Deplete melatonin levels.• Tricyclic antidepressants deplete CoQ10.

Prozac, alone, has been associated with over 1,734 suicide deaths and over 28,000 adverse reactions. Only 1-5 percent of negative drug reactions are ever reported. Prozac may be associated with 156,060 suicide deaths and 2,520,000 adverse reactions!

Prozac, alone, has been associated with over 1,734 suicide deaths and over 28,000 adverse reactions. Only 1-5 percent of negative drug reactions are ever reported. Prozac may be associated with 156,060 suicide deaths and 2,520,000 adverse reactions!

Drug side effects are often missed by doctors.Generalized muscle spasms, aches, and pains, are a common side effect of SSRI drugs.

Drug side effects are often missed by doctors.Generalized muscle spasms, aches, and pains, are a common side effect of SSRI drugs.

Sleep disturbances, either insomnia or somnolence, have been reported in about 25% of patients taking serotonin reuptake inhibitors. THIS OFTEN LEADS TO MORE DRUGS TO TREAT THE ANTIDPRESSANT SIDE EFFECTS.

Sleep disturbances, either insomnia or somnolence, have been reported in about 25% of patients taking serotonin reuptake inhibitors. THIS OFTEN LEADS TO MORE DRUGS TO TREAT THE ANTIDPRESSANT SIDE EFFECTS.

The Problem With SSRI Meds “Down-regulation”

Eventually the brain begins to reduce the number of serotonin receptors, up to 40-60 percent in some parts of the brain, until they literally disappear from the brain.

The Problem With SSRI Meds “Down-regulation”

Eventually the brain begins to reduce the number of serotonin receptors, up to 40-60 percent in some parts of the brain, until they literally disappear from the brain.

“Ortho” means correct or normal, and orthomolecular physicians recognize that in many cases of physiological and psychological disorders health can be reestablished by properly correcting, or normalizing, the balance of vitamins, minerals, amino acids, and other similar substances within the body.

“Ortho” means correct or normal, and orthomolecular physicians recognize that in many cases of physiological and psychological disorders health can be reestablished by properly correcting, or normalizing, the balance of vitamins, minerals, amino acids, and other similar substances within the body.

AnxietyNational surveys show that 5.6 million adults over the age of 65 take anti-anxiety drugs known as benzodiazepines

AnxietyNational surveys show that 5.6 million adults over the age of 65 take anti-anxiety drugs known as benzodiazepines

Benzodiazepines are addictive (within 2 weeks) and can cause a host of unwanted side effects.poor sleep, seizures, mania, depression, suicide, ringing in the ears, amnesia, dizziness, anxiety, disorientation, low blood pressure...

Benzodiazepines are addictive (within 2 weeks) and can cause a host of unwanted side effects.poor sleep, seizures, mania, depression, suicide, ringing in the ears, amnesia, dizziness, anxiety, disorientation, low blood pressure...

Nausea, fluid retention, tremors, sexual dysfunction (decreased desire and performance), weakness, somnolence (prolonged drowsiness or a trance-like condition that may continue for a number of days), and headaches.

Nausea, fluid retention, tremors, sexual dysfunction (decreased desire and performance), weakness, somnolence (prolonged drowsiness or a trance-like condition that may continue for a number of days), and headaches.

Forty percent of those age 60 or older who take tranquilizers, will experience tardive dyskinesiaFor many, these tremors are permanent.These drugs deplete CoQ10 and melatonin levels.

Forty percent of those age 60 or older who take tranquilizers, will experience tardive dyskinesiaFor many, these tremors are permanent.These drugs deplete CoQ10 and melatonin levels.

Orthomolecular Medicine

Fortunately for those looking for a safer, often times more effective way to beat mood disorders, a group of progressive minded physicians helped pioneer a new way of treating mental disorders, known as orthomolecular medicine.

Orthomolecular Medicine

Fortunately for those looking for a safer, often times more effective way to beat mood disorders, a group of progressive minded physicians helped pioneer a new way of treating mental disorders, known as orthomolecular medicine.

Patient’s who stop their mood disorder drugs may experience an assortment of unwanted side effects. The possible withdrawal symptoms include severe depression, anxiety, agitation, dizziness, spinning sensations, swaying, difficulty walking, nausea, vomiting, upset stomach, flu-like symptoms, lethargy, muscle pain, tingling or electric shock sensations, and sleep disturbances.

Patient’s who stop their mood disorder drugs may experience an assortment of unwanted side effects. The possible withdrawal symptoms include severe depression, anxiety, agitation, dizziness, spinning sensations, swaying, difficulty walking, nausea, vomiting, upset stomach, flu-like symptoms, lethargy, muscle pain, tingling or electric shock sensations, and sleep disturbances.

Amino Acid Therapy/Nutritional

TherapyNeurotransmitters are produced from the amino acids in the foods we eat. Certain amino acids along with B vitamins and minerals produce the neurotransmitters.

Amino Acid Therapy/Nutritional

TherapyNeurotransmitters are produced from the amino acids in the foods we eat. Certain amino acids along with B vitamins and minerals produce the neurotransmitters.

The neurotransmitters that cause excitatory reactions are known as catecholamines. Catecholamines, epinephrine and norepinephrine (adrenaline) are derived from the amino acid phenylalanine and tyrosine.

The neurotransmitters that cause excitatory reactions are known as catecholamines. Catecholamines, epinephrine and norepinephrine (adrenaline) are derived from the amino acid phenylalanine and tyrosine.

Inhibitory or relaxing neurotransmitters including serotonin, is produced from the amino acid tryptophan (5HTP).

Inhibitory or relaxing neurotransmitters including serotonin, is produced from the amino acid tryptophan (5HTP).

The "S" Group (S for Serotonin)

It's hard for you to go to sleep. You can't stay asleep. You often find yourself irritable. Your emotions often lack rationality. You occasionally experience unexplained tears. Noise bothers you more than it used to. It seems louder than normal. You "flare up" at others more easily than you used to. You experience unprovoked anger. You feel depressed much of the time. You find you are more susceptible to pain. You prefer to be left alone.

The "S" Group (S for Serotonin)

It's hard for you to go to sleep. You can't stay asleep. You often find yourself irritable. Your emotions often lack rationality. You occasionally experience unexplained tears. Noise bothers you more than it used to. It seems louder than normal. You "flare up" at others more easily than you used to. You experience unprovoked anger. You feel depressed much of the time. You find you are more susceptible to pain. You prefer to be left alone.

5HTP- Boosts Serotonin Levels

One study showed that patients on 5HTP had a 50 percent improvement in their mood disorder symptoms.

5HTP- Boosts Serotonin Levels

One study showed that patients on 5HTP had a 50 percent improvement in their mood disorder symptoms.

The "O" Group (O for Opioids)

The "O" Group is named for the Opioid neurotransmitters contained in the HypothalamusYour life seems incomplete. You feel shy with all but your close friends. You have feelings of insecurity. You often feel unequal to others. When things go right you sometimes feel undeserving. You feel something is missing in your life. You occasionally feel a low self-worth or esteem. You feel inadequate as a person. You frequently feel fearful when there is nothing to fear.

The "O" Group (O for Opioids)

The "O" Group is named for the Opioid neurotransmitters contained in the HypothalamusYour life seems incomplete. You feel shy with all but your close friends. You have feelings of insecurity. You often feel unequal to others. When things go right you sometimes feel undeserving. You feel something is missing in your life. You occasionally feel a low self-worth or esteem. You feel inadequate as a person. You frequently feel fearful when there is nothing to fear.

The "G" Group (G for GABA)

You often feel anxious for no reason. You sometimes feel "free floating" anxiety. You frequently feel "edgy" and it's difficult to relax. You often feel a "knot" in your stomach. Falling asleep is sometimes difficult. It’s hard to turn your mind off when you want to relax. You occasionally experience feelings of panic for no reason. You often use alcohol or other sedatives to calm down.

The "G" Group (G for GABA)

You often feel anxious for no reason. You sometimes feel "free floating" anxiety. You frequently feel "edgy" and it's difficult to relax. You often feel a "knot" in your stomach. Falling asleep is sometimes difficult. It’s hard to turn your mind off when you want to relax. You occasionally experience feelings of panic for no reason. You often use alcohol or other sedatives to calm down.

Use GABA or L-Theanine to boost GABA levels

Use GABA or L-Theanine to boost GABA levels

The "D" Group (D for Dopamine)

You lack pleasure in life. You feel there are no real rewards in life. You have unexplained lack of concern for others, even loved ones. You experience decreased parental feelings. Life seems less "colorful" or "flavorful." Things that used to be "fun" aren’t any longer enjoyable. You have become a less spiritual or socially concerned person.

The "D" Group (D for Dopamine)

You lack pleasure in life. You feel there are no real rewards in life. You have unexplained lack of concern for others, even loved ones. You experience decreased parental feelings. Life seems less "colorful" or "flavorful." Things that used to be "fun" aren’t any longer enjoyable. You have become a less spiritual or socially concerned person.

Use L-Phenylalanine or SAMe to boost dopamine levels

Use L-Phenylalanine or SAMe to boost dopamine levels

The "N" Group (N for Norepinephrine)

You suffer from a lack of energy. You often find it difficult to "get going." You suffer From decreased drive. You often start projects and then don't finish them. You frequently feel a need to sleep or "hibernate." You feel depressed a good deal of the time. You occasionally feel paranoid. Your survival seems threatened. You are bored a great deal of the time.

The "N" Group (N for Norepinephrine)

You suffer from a lack of energy. You often find it difficult to "get going." You suffer From decreased drive. You often start projects and then don't finish them. You frequently feel a need to sleep or "hibernate." You feel depressed a good deal of the time. You occasionally feel paranoid. Your survival seems threatened. You are bored a great deal of the time.

Use L-Phenylalanine or SAMe to boost norepinephrine levels

Use L-Phenylalanine or SAMe to boost norepinephrine levels

S- Adenosyl-methionine (SAMe)

SAMe IS one of the best natural antidepressants available. SAMe helps boost serotonin and epinephrine levels. Combining SAMe with prescription antidepressants reduces the failure rate by 43%. There are over 100 peer-reviewed studies showing that SAMe is a safe and effective antidepressant.

S- Adenosyl-methionine (SAMe)

SAMe IS one of the best natural antidepressants available. SAMe helps boost serotonin and epinephrine levels. Combining SAMe with prescription antidepressants reduces the failure rate by 43%. There are over 100 peer-reviewed studies showing that SAMe is a safe and effective antidepressant.

Essential Fatty Acid Imbalances

Research shows that low blood levels of omega 3 essential fatty acids are associated with depression. Restoring proper omega 6 to omega 3 ratio’s is important in optimizing neurotransmitter function.

Essential Fatty Acid Imbalances

Research shows that low blood levels of omega 3 essential fatty acids are associated with depression. Restoring proper omega 6 to omega 3 ratio’s is important in optimizing neurotransmitter function.

B-vitamins play a crucial role in the production of neurotransmitters. A deficiency in any of the B-vitamins will increase the risk of mood disorders.

B-vitamins play a crucial role in the production of neurotransmitters. A deficiency in any of the B-vitamins will increase the risk of mood disorders.

Folic acid is needed for the creation of catecholamines (norepinephrine, dopamine, and epinephrine).

Folic acid deficiency is common in the United States.

Folic acid is dependant on B12, B3 and Vitamin C to be converted into its active form.

Folic acid is needed for the creation of catecholamines (norepinephrine, dopamine, and epinephrine).

Folic acid deficiency is common in the United States.

Folic acid is dependant on B12, B3 and Vitamin C to be converted into its active form.

Studies show that Folic acid is more effective than standard prescription antidepressants.

92% of those treated with folic acid made a full recovery, while only 70% of the control group (those taking antidepressants) made a full recovery. Studies that combining folic acid with a SSRI (Prozac) was more effective than taking the prescription drug alone.

Studies show that Folic acid is more effective than standard prescription antidepressants.

92% of those treated with folic acid made a full recovery, while only 70% of the control group (those taking antidepressants) made a full recovery. Studies that combining folic acid with a SSRI (Prozac) was more effective than taking the prescription drug alone.

Thiamine or vitamin B1 deficiency can cause anxiety and depression.It’s needed to manufacture the neurotransmitter largely responsible for memory, known as acetylcholine. Up to 50% of the elderly in the U.S. are deficient in thiamine.

Thiamine or vitamin B1 deficiency can cause anxiety and depression.It’s needed to manufacture the neurotransmitter largely responsible for memory, known as acetylcholine. Up to 50% of the elderly in the U.S. are deficient in thiamine.

Riboflavin or vitamin B2 is needed for the production of serotonin, norepinephrine, and dopamine.

Riboflavin or vitamin B2 is needed for the production of serotonin, norepinephrine, and dopamine.

Pyridoxine or vitamin B6 is needed to convert the amino acids into the neurotransmitters.

Some folks may have a difficult time convert pyridoxine into the more active pyridoxal-5-phosphate (P-5-P).

Pyridoxine or vitamin B6 is needed to convert the amino acids into the neurotransmitters.

Some folks may have a difficult time convert pyridoxine into the more active pyridoxal-5-phosphate (P-5-P).

Those suffering from a B6 deficiency may have Pyroluria.This is a genetic glitch that causes an over formation of kryptopyrroles (normally a byproduct of hemoglobin metabolism).These chemicals bind to aldehyde chemicals and block pyridoxine and zinc.This may be found in up to 40% of those with a mood disorder.

Those suffering from a B6 deficiency may have Pyroluria.This is a genetic glitch that causes an over formation of kryptopyrroles (normally a byproduct of hemoglobin metabolism).These chemicals bind to aldehyde chemicals and block pyridoxine and zinc.This may be found in up to 40% of those with a mood disorder.

Individuals suffering with Pyroluria typically have the following characteristics:fair skin, don’t dream at night, history of cluster headaches, PMS, anemia, cold hands and feet, tingling sensations, motion sickness, poor immune function,, white spots on their nails, sensitivity to sunlight, and a dislike to protein foods.Test kits available from Bio Center Laboratory 1-888-494-7785

Individuals suffering with Pyroluria typically have the following characteristics:fair skin, don’t dream at night, history of cluster headaches, PMS, anemia, cold hands and feet, tingling sensations, motion sickness, poor immune function,, white spots on their nails, sensitivity to sunlight, and a dislike to protein foods.Test kits available from Bio Center Laboratory 1-888-494-7785

Low thyroid function

Stress, depression, anxiety and fatigue are all associated with low thyroid function. Thyroid hormones help regulate concentration, mental clarity, moods, and proper brain chemistry. T3 therapy is more effective in reducing the symptoms associated with depression than SSRI antidepressants.

Low thyroid function

Stress, depression, anxiety and fatigue are all associated with low thyroid function. Thyroid hormones help regulate concentration, mental clarity, moods, and proper brain chemistry. T3 therapy is more effective in reducing the symptoms associated with depression than SSRI antidepressants.

Triiodothyronine or T3, one of the thyroid hormones regulates the levels and actions of the brain chemicals serotonin, norepinephrine, and gamma-amino butyric acid (GABA). Serotonin is decreased when T3 levels become deficient, a more common occurrence than might be suspected.

Triiodothyronine or T3, one of the thyroid hormones regulates the levels and actions of the brain chemicals serotonin, norepinephrine, and gamma-amino butyric acid (GABA). Serotonin is decreased when T3 levels become deficient, a more common occurrence than might be suspected.

Thyroid Tests are Often Inaccurate

Blood tests only measure the amount of thyroid hormones circulating in the blood, one second out of minute of the day. They can’t measure how much hormone is actually in the cells. Therefore blood tests are an educated guess.

Thyroid Tests are Often Inaccurate

Blood tests only measure the amount of thyroid hormones circulating in the blood, one second out of minute of the day. They can’t measure how much hormone is actually in the cells. Therefore blood tests are an educated guess.

What can go Wrong?Inaccurate blood test

Don’t know how much of hormone is in cell where it becomes activeUse old criteria TSH above 5 to be diagnosed with hypothyroidNew criteria as recommended by ACE advocates treating with thyroid replacement therapy when TSH is above 3.04Thyroxine (T4) may not be converting to triiodothyronine (T3).

What can go Wrong?Inaccurate blood test

Don’t know how much of hormone is in cell where it becomes activeUse old criteria TSH above 5 to be diagnosed with hypothyroidNew criteria as recommended by ACE advocates treating with thyroid replacement therapy when TSH is above 3.04Thyroxine (T4) may not be converting to triiodothyronine (T3).

Natural Herbal AntidepressantsNatural Herbal Antidepressants

Randomized double-blind, placebo-controlled studies, involving 1,757 people with mild to moderate depression, shows that herb St. John’s Wort, was nearly three times superior to placebo in relieving depressive symptoms.

Randomized double-blind, placebo-controlled studies, involving 1,757 people with mild to moderate depression, shows that herb St. John’s Wort, was nearly three times superior to placebo in relieving depressive symptoms.