ucsf informatics day 2014 - priyanka agarwal, "center for digital health innovation"

Center for Digital Health Innovation at UCSF

San Francisco, June 10, 2014

Priyanka Agarwal

Rhona Snyman

UCSF’s Center for Digital Health Innovation

Center for Digital Health Innovation at UCSF

About us

2

Center for Digital Health Innovation at UCSF

Road Map

3

• Overview of CDHI

• UCSF/Samsung Innovation Lab

• Internal Innovation

• External Partnerships

• CDHI & the ITA

Center for Digital Health Innovation at UCSF

CDHI Overview

Center for Digital Health Innovation at UCSF

The Vision

5

To improve health worldwide, we

envision and realize new technologies,

developed at UCSF and beyond, and

evaluate them in clinical settings.

Guided by science, we catalyze the

new era of precision medicine.

Center for Digital Health Innovation at UCSF 6

The context: Interest in digital health is growing

186 companies funded >2M in 2013

Center for Digital Health Innovation at UCSF 7

…And little involvement from medicine

186 companies funded >2M in 2013

Center for Digital Health Innovation at UCSF 8

Enter CDHI

Center for Digital Health Innovation at UCSF 9

Focus

Center for Digital Health Innovation at UCSF

Unique Value Proposition

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• Unified team of MDs, IT engineers, EHR experts, clinical

trial specialists, and security specialists

• Access to UCSF’s clinical trial and research infrastructure

• Deep knowledge around EHR integration and development

Center for Digital Health Innovation at UCSF

Team

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CMIOs Engineers ResearchersSecurity experts

Medical Educators

Licensing Officers

Project managers

Center for Digital Health Innovation at UCSF

Team

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Center for Digital Health Innovation at UCSF 13

Key UCSF Partners for Success

CDHI

ITACHR

ITS

PLR

CHCV

CTSIQB3

MedCtrIT

SOM

ISU

COI

Center for Digital Health Innovation at UCSF

Endpoints for success

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• In collaboration with faculty, staff, start-ups, and industry partners new digital

health concepts and technologies are reaching the market

• CDHI trials of new digital health technologies are published in scientific

journals, with UCSF seen as a leader for the validation of new technologies

• New partnerships with industry and venture capital leaders are in place to

accelerate dHealth innovation and public benefit

Center for Digital Health Innovation at UCSF

UCSF/Samsung Digital Health Innovation Lab

Center for Digital Health Innovation at UCSF

Mission

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To accelerate validation and commercialization of

promising new sensors, algorithms, and digital health

technologies for preventive health solutions

Center for Digital Health Innovation at UCSF

First collaboration: Simband & the Sami Platform

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Center for Digital Health Innovation at UCSF

Sami Platform

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Center for Digital Health Innovation at UCSF 19

Samsung Innovation Lab

Center for Digital Health Innovation at UCSF 20

Working Across Spheres

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CONSUMERS

• engagement

• motivation

• education

• Communication

CLINICIANS

• Beside tools

• diagnostic &

decision support

• process efficiency

RESEARCHERS

• data collection

• behavior change

• real-time feedback

• collaboration

Center for Digital Health Innovation at UCSF

CDHI & Internal Innovation

Center for Digital Health Innovation at UCSF

Internal Innovation Goals

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• Incubate best of internally developed technologies

• Support promising technologies via Catalyst award

• Promote commercialization via external partnerships (Samsung center, other startup/later-stage partnerships)

Center for Digital Health Innovation at UCSF 23

Innovation: Inaugural Portfolio

Center for Digital Health Innovation at UCSF 24

Case Study: Health eHeart

Center for Digital Health Innovation at UCSF

Case Study: eReferrals & AristaMD

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• UCSF PIs developed successful technology at UCSF

• Interest in commercializing technology with AristaMD

• Need to balance PI interests with those of UCSF

• Need to convey process for external partnership to PIs

• Conflict of interest

• Income distribution

Center for Digital Health Innovation at UCSF

CDHI & External Activities

Center for Digital Health Innovation at UCSF

External Innovation Goals

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• Co-development deals with UCSF supporting technical & workflow development

• Clinical Trial development & support

• Goal for partnership rather than fee-for-service arrangement

Center for Digital Health Innovation at UCSF

Opportunities for external partners at CDHI

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Clinical expertise

Patient expertise

Data

Workflow integration

Technical (EHR) Integration

Clinical trial design and implementation

FDA guidance

Privacy, risk guidance

Access to network of hospitals, clinics, care networks

Center for Digital Health Innovation at UCSF

Framework for External Partnerships

2929

Initial MeetingITA

involvement

Technical co-development

plan

Trial co-development

planImplementation

Implementation

Scientist

PIRA

Ongoing

involvement

EHR

Integration

Trial design,

clinical workflows

Industry Partnerships

BAA, privacy, riskEPIC interfaces

team

PI recruitment,

pharmacy, RN

Decision

to engage

Demo Day

Industry Partnership

Advisory Board

Center for Digital Health Innovation at UCSF

Experience to date

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• ~60 early-stage companies

have reached out to CDHI

since August 2013

• Each company asked to fill

out intake survey

• Demo Days held every 4-6

weeks for CDHI team to

meet with multiple

companies

Center for Digital Health Innovation at UCSF

Case Study: Smartdose

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Center for Digital Health Innovation at UCSF

Smartdose: Considerations raised

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• Storage of data: Cloud-based or on premise?

• Outline of financials for collaborative agreement: Upfront or

upon completion of work?

• Language around IP development: UCSF with first right of

refusal?

Center for Digital Health Innovation at UCSF

Thank You

Center for Digital Health Innovation at UCSF

Integration: EMERGE

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M institutions + N Apps

Center for Digital Health Innovation at UCSF 3535

Distinct from our Competitors

Center for Digital Health Innovation at UCSF

Demo Day

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• Monthly opportunity for multi-disciplinary CDHI team to

hear from multiple companies in a brief period

• Initial session held on 3/11/2014

• Plan to invite other domain experts, co-sponsors

• Tracking success of companies both accepted and

declined

Center for Digital Health Innovation at UCSF

Takeaways

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• Heightened interest in healthcare space

• Cloud computing considerations

• Risk considerations for UCSF vs Smartdose

Center for Digital Health Innovation at UCSF

Life cycle of a partnership

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Initial MeetingIP office

involvement

Technical co-development

plan

Trial co-development

planImplementation

Implementation

Scientist

PIRA

Center for Digital Health Innovation at UCSF

Life cycle of a partnership

39

Initial MeetingIP office

involvement

Technical co-development

plan

Trial co-development

planImplementation

Decision

to engage

Demo Day

Industry Partnership

Advisory Board

Center for Digital Health Innovation at UCSF

Life cycle of a partnership

40

Initial MeetingIP office

involvement

Technical co-development

plan

Trial co-development

planImplementation

Decision

to engageFunding Funding Funding

IT, security,

providersFaculty

member

Research

Assistant

Demo Day Industry Partnerships

Industry Partnership

Advisory Board

Center for Digital Health Innovation at UCSF

Status of partnership

4141

Initial MeetingIP office

involvement

Technical co-development

plan

Trial co-development

planImplementation

Implementation

Scientist

PIRA

Ongoing

involvement

EHR

Integration

Trial design,

clinical workflows

Industry Partnerships

BAA, privacy, riskEPIC interfaces

team

PI recruitment,

pharmacy, RN