Clinical and TranslationalScience Institute / CTSIat the University of California, San Francisco

Amuse-bouche: The Palate for ChangeClinical Research Services in 2011

CTSI Annual RetreatJuly 28, 2011

Clinical Research Services

• Cost Recovery Initiative– Lynda Jacobsen

• Participant Recruitment Core Services– Nariman Nasser

• Clinical Coordinator Core Services– Danusia Filipowski, MD

COST RECOVERY INITIATIVE

Cost Recovery Goals

• To continue providing high quality core services to support clinical research at UCSF and beyond

• To work with investigators to expand services to meet their emerging needs

• To understand the cost of providing services

• To optimize use of facilities and resources

Why Cost Recovery Now?

• We face cumulative pressures– increasing costs– fiscal constraints– anticipated decreases in NIH funding support

• To introduce a “shared investment” approach to leveraging all available funding sources to support needed services

• To ensure prudent resource management

Cost Recovery Principles

• Established by Cost Recovery Task Force to guide development of cost recovery policies

• “Grandfathers” current studies under agreements in place at the time the original budget was developed

• Proposes a minimum contribution of 40% of CRS cost for new, revised and competing grant applications

• Commitment to working with investigators to address funding constraints

Next Steps

• Communicate principles to campus investigators and key stakeholders

• Continue costing new and renewal proposals using estimated rates

• Develop and publish formal recharge rates for every core service

• Refine internal procedures to ensure timely responses to investigator inquiries

PARTICIPANT RECRUITMENT CORE SERVICES

SUPPORT INCREASE IMPROVE

INCREASE

CLINICAL COORDINATOR CORE SERVICES

• A new CTSI service inspired by investigator’s needs and requests

• Piloted by Drs. Wara, Puck and Milojevic for 1 year in 2010• 1 coordinator• ~ 4 studies

• CRC-Core was created in August 2010 as an official CTSI service

• In 10 months we have grown to a staff of 5, with 1 position pending

• Coordinator support is 80% recharge from PI’s, 20% CTSI

Our Origins:

Clinical Research Coordinator Core

Image: iStockphoto/Mark Evans

Clinical Research Coordinator Core

Our Development:

1. Coordinator Services: Full study support

a. All UCSF PI’sb. All departments and all specialtiesc. All locations where UCSF PI’s conduct researchd. Everything else … within reason

2. Education initiative:

a. Curriculumb. Certification program

3. “Switchboard” of coordinator services

Image from: http://www.beappreciative.com

Clinical Research Coordinator Core

Image from: http://www.dailymail.co.uk

Our In-duck-tion:

• 45 requests for service

• 32 studies supported

• 5 early career investigators

• Current sites:• Parnassus: 12M, 6M, ER, ICU, Inpatient and outpatient

• Mount Zion: 6West

• SFGH: Inpatient and outpatient CRS unit (4C/5B)

• Satellite sites: RAI dialysis centers on Haight & Cesar Chavez

• SFVA: Pending accreditation and access.

• Current specialties:• 1/3 Pediatric, 2/3 Adult

• IM, OB/Gyn, Surgery

• Immune/BMT, Rheum, Hep, ID, Neuro, Heme/Onc, Nephro, Cardio, Environmental Health, GU, Early Phase Caner Center, etc.