WELCOME TO

MY PRESENTATION

Presented byAshraf Elahi

ID: FST-13/39Registration no.: 00905

Dept. of Applied Food Science & NutritionFaculty of Food Science & Technology

Chittagong Veterinary & Animal Sciences UniversityJakir Hossain Road, Khulshi, Chittagong-4202, Bangladesh

Presentation Topic : Appraisal of an original article on CHILDHOOD EPILEPSY

• Published on the Journal of the college of Physicians and Surgeons of Pakistan 2011 Vol. 21(2): 74-78

• Correspondence: Dr. Muhammad Akbar Malik, Dept. of Paediatric Neurology, The children’s Hospital, lahore, Pakistan

A neurological disorder marked by sudden recurrent episodes of sensory disturbance, loss of consciousness, or convulsions, associated with abnormal electrical activity in the brain as well as neuron

Excitory nurotransmitter -GlutamateInhibitory neurotransmitter- GABA

• .

Summary

The cross-sectional study was conducted to observe prevalence and treatment gap of childhood epilepsy in rural and urban population of panjab.They followed ILAE and Ecuador to generate proforma and questionnaire during training and developing research tools. Then trained field officers were applied to manipulate the survey. Finally catch-recatch technique was accomplished for registration & diagnosis of missed case. Eventually seizure classification, treatment gap definition, Chi-square test and documentation processes were effectuated to meet ultimate result of the study.

Strong points

• Strategic motivation for survey• Qualified field worker• Pre-designed profoma• Proficient identification of treatment gap• Using updated SPSS version of software• Training arrangement for field worker

Weak points• Cluster sampling of only 10 out of 52

total union council• EEG (electroencephalographic) data

lacking• Sampling from a limited region• Age group limitation• Sampling duration

ResultPrevalence of childhood epilepsy was found to

be 7.0/1000 within similar distributionTreatment gap was found in 88% patientPatient being managed by disqualified person

and quacks are about 66%

Comment

• Considering overall status of the study it was a well defined cross sectional study as it performed to meet the desired goal to know the prevalence and treatment gap of the study indeed. But the result was not enough to generate hypothesis for further study design due to it’s limited sampling area.

Suggestions

• Sample size should be larger• Sampling area should be country-wide not

only one district• Modern diagnostic instruments should have to

be installed in rural and semi-urban region to ensure authentic diagnosis and data collection.

Conclusion• Due to unknown etiology the disease epilepsy is

not controlled following any prevention. So we have to research more to discover it’s verified etiology & prevention. The study I reviewed in this presentation was one of the great journey to achieve ins and outs epilepsy. However, the cross-sectional randomized cluster study has added a new dimension to the medical science by meeting it’s predefined objective.

Thanks to all for your kind support

Reference slides

In a "tonic" seizure, the tone is greatly increased and the body, arms, or legs make sudden stiffening movements. Consciousness is usually preserved. Tonic seizures most often occur during sleep and usually involve all or most of the brain, affecting both sides of the body.

In the tonic phase the body becomes entire rigid, and in the clonic phase there is uncontrolled jerking. Tonic-clonic seizures may or may not be preceded by an aura, and are often followed by headache, confusion, and sleep. They may last mere seconds, or continue for several minutes. Also known as a grand mal seizure.

• Globally it is estimated that there are nearly 50 million patients suffering from epilepsy, of which three-fourth.

• Bangladesh: Though there are no national statistics, it is estimated that there are at least 1.5– 2.0 million people with epilepsy in Bangladesh, ie about 12 people with epilepsy per 1000 population.

• Types of anticonvulsants available in SEAR Bangladesh: Carbamazepine, phenytoin, phenobarbital, sodium valproate