UCLA Pathology and Laboratory Medicine—Holiday Edition 2016 | Page 1

Holiday Newsletter—2016

Ins

AWARDS & RECOGNITIONS,

2

EVENTS AND DEPARTMENT

NEWS

3

NEW EMPLOYEES 4

PUBLICATIONS 5/6

U C L A P A T H O L O G Y A N D L A B O R A T O R Y M E D I C I N E

Q U A R T E R L Y N E W S L E T T E R

UCLA Health Path & Lab Med Volunteers—Care Harbor

October 15-18 2015

Care Harbor is a major opportunity for our department volunteers to

reach the people most important to their mission – all under one roof

at one time. The men and women attending this free clinic are an

accessible and eager audience as they wait, often for hours, for the

health services they request. Charities, organizations and govern-

ment agencies can connect with their public enmasse with great effi-

ciency and impact.

Care Harbor provides free medical, dental and vision care to the

uninsured, underinsured and underserved in our communities. For

those who live without access to the care they need, our clinic events

are a destination for help and hope.

There is space for exhibits and presentations that educate and inform

patients as well as provide them with needed services. Our goal is to

promote the wellness and wellbeing of the people we serve - some

of our most vulnerable populations – with prevention and education-

al resources.

Lavita Boyd led a group of volunteers at the CareHarbor

LA event in October.

Luzviminda Cutidioc-Padilla HopeAngel Mayberry

Lissette Renteria Kellie Brown

Rachael Rader Candie Bautista

Lilian Baldwin Dawn Stene

Salpi Janetsian Pateel Janetsian

Iliana R. Ruiz Shelly Rajput

Annual 2015 Holiday Party

The Department of Pathology & Laboratory Medi-

cine continues its wonderful Holiday Party tradition.

Below are highlights of the festivities.

Click here for more pictures.

Inside this issue:

UCLA Pathology and Laboratory Medicine—Holiday Edition 2016 | Page 2

Awards and Recognitions

Congratulations to Dr. Xinmin Li and Clini-

cal Microarray Core (CMC) for completing

the 10th NGS workshop. | Read More

Dr. Jonathan Braun featured in a U Magazine

Article: Interior Life. | Read More

Dr. Romney Humphries and UCLA Clinical

Microbiology are highlighted in the August

1, 2015 Los Angeles Times article, ―A Killer

on the Loose‖. | Read More .

Additionally, Dr. Humphries and the entire

Clinical Microbiology team were featured in

CAP Today, ―Superbugs on Scopes, How

UCLA Lab discovered the out-

break‖( page 74). | Read More

Dr. Joshua Deignan was interviewed for CAP

today. | Read More

Congratulations to Dr. Linda Baum on her new

appointment as Associate Dean for Medical

Student Research and Scholarship in the David

Geffen School of Medicine at UCLA.

Congratulations to Dr. Kenneth Dorshking on

being named the Interim Director of the Jons-

son Comprehensive Cancer Center and Presi-

dent of the Jonsson Cancer Center Foundation.

| Read More We are delighted to announce the appointment

of Dr. Alyssa Ziman as Medical Director of the

Clinical Laboratories for Ronald Reagan

UCLA Medical Center, effective Oct. 1, 2015. |

Read More

Congratulations to Sheri Klein (below) for her 40th anniver-

sary at UCLA.

Congratulations to Mabel Pang for her 30 years of service in

our department.

Congratulations to John Muramoto for his 30

years of service in our department.

Congratulations to Dr. Jonathan E. Zuckerman,

recipient of the 2015 Daljit S. and Elaine

Sarkaria Fellowship.

Congratulations Dr. Jin on re-

ceiving the ASHI Scholar

Award! His abstract OR37: AN-

TIBODY LIGATION OF HLA

B*44:03 FAILS TO STIMU-

LATE ENDOTHELIAL CELL

PROLIFERATION DUE TO A

FAILURE TO RECRUIT INTEGRIN BETA4. was one of the

highest scoring abstracts submitted this year.

Congratulations to Dr. Michael Fishbein and

Dr. Gregory Fishbein for their article pub-

lished in Cardiovascular Pathology,

―Arteriosclerosis: facts and fancy‖ Read More

Congratulations to Dr. Aaron James on his pub-

lication in the American Journal of Pathology.

Read More

Congratulations to Dr. Jeffrey Goldstein on

being appointed Trustee of The American

Board of Pathology for 2016.

UCLA Pathology and Laboratory Medicine—Holiday Edition 2016 | Page 3

Department News

UCLA Blood & Platelet Center

The UCLA Blood & Platelet Center conducted a live broadcast with Nataly Valenzuela

from Univision. Nataly has been a donor with us for many years and as the Blood and Plate-

let Center (BPC) explores new avenues to advertise and obtain donors, it made perfect sense

to have Nataly conduct a segment on her morning show debuting the BPC's work and it's

importance to our community. We opened early for the show to

broadcast live at 05:19 a.m. on a Monday morning. The show is

geared towards the Spanish community and relayed entirely in Spanish. The BPC believes this

to be a great community and culture to target and provide insight to regarding the process, pur-

pose and importance of donating and giving back. As the BPC moves forward, we are con-

stantly looking for new and innovative ways to obtain more donors and increase blood supply

for UCLA Health. You will be seeing more of us! Come donate & Give back.

UCLA Researchers Create

Smartphone-based Device

This device reads medical diag-

nostic test rapidly and accurate-

ly. A team of researchers from

the California NanoSystems Institute at UCLA has devel-

oped a new mobile phone-based device that can read

ELISA plates in the field with the same level of accuracy

as the large machines normally found in clinical laborato-

ries... Read more

UCLA Blood and Platelet Center—2015

Volkswagen City of Angels Fun Ride

Biking angels raise $48,000 for

UCLA Blood and Platelet Center.

This year the event was launched

from UCLA’s Dickson Plaza and

more than 800 people participated.

Read More

Dr. Omai Garner’s Interview on

Lab TV -

―Curious About New Ways of

Testing for Infectious Diseases‖.

Watch here.

Greater Los Angeles County Heart Walk

Saturday, September

26, 2015 | Rose Bowl

The Department of Pathol-

ogy & Laboratory Medi-

cine touches virtually each

and every patient in the

hospital, assisting in their diagnosis and treatment.

A total of 63 team members raised $6,837.00 for

the American Heart Association's research and ed-

ucation programs.

UCLA Immunogenetics Center Annual

Pumpkin Contest

UCLA Pathology and Laboratory Medicine—Holiday Edition 2016 | Page 4

Welcome New Employees and Students

August 12, 2015

November 18, 2015

October 13, 2015

December 8, 2015

Saul Sanchez Ramos – HLT II, Cytogenetics

Chuong Vu – HLT II, Cytology

Sze Man (Annabella) Leung – CLS, Molecular Diagnostics

Kimberly Marquez - CPT II, RRH Support Services

January 13, 2016

Mehrnaz Forough – CLS Flow Cytometry/Bone Marrow Lab

Louella E. Obusan – CPT, Support Services

Yenling Yang – Hosp Information Coder, Support Services

Starr C. Steen – CPT, Support Services

Sujata Mahangare – CLS, Brentwood

Cynthia Antekelian – HLT II, Blood & Platelet Center

Jun Chen – Cytogenetics Technologist, Cytogenetics

Vicky Nguyen – Sr. Adm Analyst, Blood & Platelet Center

Cathrine Chong – CLS, Microbiology

Alejandra Cortez – CLS, Serology

Juan Carlos Espinoza – HLT II, Comp. Processing Lab

Christopher Franco – CPT II, SMH

Jasmine Fung – HLT II, Virology

Kristine Gih – CLS, Microbiology

Felipe Landero – CPT, SMH

Jennifer Nguyen – HLT II, Comp. Processing Lab

Joseph B. Nolasco – CLS, Blood Bank

Leslie Ocampo – HLT II, Comp. Processing Lab

Gabriela Paniagua – HLT II, Anatomical Path.

Corey Rich – CLS, Virology

Front Row: Anna Fafard – CLS, SMH,

Sarah Gutknecht – CLS, Brentwood Annex

Jin Park – CLS, Brentwood Annex

Middle Row: Crystal Romero – CPT II, SMH

Poan Wang – CLS, SMH

Kevin Huynh – Adm Specialist, Regulatory Affairs,

Rui Ma – CLS, Brentwood Annex

Back Row: Desalegn Babeta – CPT, RRH

Nelson Siron – CPT II, RRH

Marina Aguilar – HLT I, BURL

Daniel Allen – CLS Apprentice, Cytogenetics

Kyle Bernier – Lab Analyst, Path Operations Mgmt

Tyler Burdick – Path Assistant, Surg Path

Maloney Chester – Manager, Cyotgenetics

Diane Glenn – CLS, Microbiology

Yumina Hurrell – CLS , Serology

Julie Luong – CLS, Toxicology

Victor Ortega – CLS Apprentice, Cytogenetics

Wilhma Petilla – CLS, Transfusion Med

William Purcell – HLT, BURL

Amy Shayne – Admin Specialist, Brentwood

Evelyn Solano – HLT, BURL

UCLA Pathology and Laboratory Medicine—Holiday Edition 2016 | Page 5

One of the goals of the Pathology Research Alumni Committee is to highlight publications from our current and

recently former graduate students, postdoctoral fellows, and residents in the departmental newsletter. If anyone

has additional publications (newly published, first-author only) that should be highlighted, please contact Doug

Smoot (dsmoot@mednet.ucla.edu).

PATHOLOGY RESEARCH ALUMNI COMMITTEE & PUBLICATIONS

-- Joshua Deignan, PhD, FACMG, Assistant Professor, Pathology & Laboratory

Medicine, Chair, Pathology Research Alumni Committee

July 2015—November 2015

GSRs:

Michael Arensman – CMP Student (David Dawson

Lab)

Calcipotriol Targets LRP6 to Inhibit Wnt Signaling in Pan-

creatic Cancer.

Arensman MD, Nguyen P, Kershaw KM, Lay AR, Oster-

tag-Hill CA, Sherman MH, Downes M, Liddle C, Evans

RM, Dawson DW.

Mol Cancer Res. 2015 Nov;13(11):1509-19. doi:

10.1158/1541-7786.MCR-15-0204. Epub 2015 Jul 29.

Airie Kim – CMP Student (Tomas Ganz Lab )

Isocitrate treatment of acute anemia of inflammation in a

mouse model.

Kim A, Fung E, Parikh SG, Gabayan V, Nemeth E, Ganz

T.

Blood Cells Mol Dis. 2016 Jan;56(1):31-6. doi: 10.1016/

j.bcmd.2015.09.007. Epub 2015 Sep 28.

Jennifer King – CMP Student (Ram Raj Singh Lab)

Langerhans Cells Maintain Local Tissue Tolerance in a

Model of Systemic Autoimmune Disease.

King JK, Philips RL, Eriksson AU, Kim PJ, Halder RC,

Lee DJ, Singh RR.

J Immunol. 2015 Jul 15;195(2):464-76. doi: 10.4049/

jimmunol.1402735. Epub 2015 Jun 12.

Norma Rodriguez-Malave – CMP Student (Dinesh Rao

Lab)

Long non-coding RNAs in hematopoietic malignancies.

Rodríguez-Malavé NI, Rao DS.

Brief Funct Genomics. 2015 Nov 26. pii: elv047. [Epub

ahead of print].

Sahar Salehi – CMP Student ( Elaine F. Reed Lab)

The divergent roles of macrophages in solid organ trans-

plantation.

Salehi S, Reed EF.

Curr Opin Organ Transplant. 2015 Aug;20(4):446-53.

doi: 10.1097/MOT.0000000000000209. Review.

Post Docs:

Jinkuk Choi – Postdoc (Peter Tontonoz Lab)

The E3 ubiquitin ligase Idol controls brain LDL receptor

expression, ApoE clearance, and Aβ amyloidosis.

Choi J, Gao J, Kim J, Hong C, Kim J, Tontonoz P.

Sci Transl Med. 2015 Nov 18;7(314):314ra184. doi:

10.1126/scitranslmed.aad1904.

Ayaka Ito – Postdoc (Peter Tontonoz Lab)

LXRs link metabolism to inflammation through Abca1-

dependent regulation of membrane composition and TLR

signaling.

Ito A, Hong C, Rong X, Zhu X, Tarling EJ, Hedde PN,

Gratton E, Parks J, Tontonoz P.

Elife. 2015 Jul 14;4:e08009. doi: 10.7554/eLife.08009.

Steven David Lee – Postdoc (Peter Tontonoz Lab)

Liver X receptors at the intersection of lipid metabolism

and atherogenesis.

Lee SD, Tontonoz P.

Atherosclerosis. 2015 Sep;242(1):29-36. doi: 10.1016/

j.atherosclerosis.2015.06.042. Epub 2015 Jul 2. Review.

No abstract available.

Sandra Thiemann - Postdoc (Linda Baum Lab)

Galectin-1 regulates tissue exit of specific dendritic cell

populations.

Thiemann S, Man JH, Chang MH, Lee B, Baum LG.

J Biol Chem. 2015 Sep 11;290(37):22662-77. doi:

10.1074/jbc.M115.644799. Epub 2015 Jul 27.

Residents/Fellows:

Durga Cherukuri – Recent Fellow (Wayne Grody Lab)

Instability of a dinucleotide repeat in the 3'-untranslated

region (UTR) of the microsomal prostaglandin E synthase-

1 (mPGES-1) gene in microsatellite instability-high (MSI-

H) colorectal carcinoma.

Cherukuri DP, Deignan JL, Das K, Grody WW, Hersch-

man H.

Mol Oncol. 2015 Aug;9(7):1252-8. doi: 10.1016/

j.molonc.2015.01.009. Epub 2015 Mar 5.

UCLA Pathology and Laboratory Medicine—Holiday Edition 2016 | Page 6

Newsletter Committee: Arnold Scheer, Daisy Castro, Bushra Yasin, and Khanh Andrews

Send us your suggestions for future newsletters at : Email Dcastro@mednet.ucla.edu

Publications Continued

Gregory Fishbein - Fellow

Arteriosclerosis: facts and fancy.

Fishbein MC, Fishbein GA.

Cardiovasc Pathol. 2015 Nov-Dec;24(6):335-42. doi:

10.1016/j.carpath.2015.07.007. Epub 2015 Aug 5. Re-

view.

Aaron James - Resident

Coincident liposarcoma, carcinoid and gastrointestinal

stromal tumor complicating type 1 neurofibromatosis:

Case report and literature review.

James AW, Chang L, Genshaft S, Dry SM.

J Orthop. 2014 Nov 26;12(Suppl 1):S111-6. doi: 10.1016/

j.jor.2014.08.010. eCollection 2015 Oct. Review.

Diagnostically Challenging Epithelioid Soft Tissue Tu-

mors.

James AW, Dry SM.

Surg Pathol Clin. 2015 Sep;8(3):309-29. doi: 10.1016/

j.path.2015.05.002. Review.

Rina Kansal – Recent Fellow (Wayne Grody Lab)

An infant with MLH3 variants, FOXG1-duplication and

multiple, benign cranial and spinal tumors: A clinical ex-

ome sequencing study.

Kansal R, Li X, Shen J, Samuel D, Laningham F, Lee H,

Panigrahi GB, Shuen A, Kantarci S, Dorrani N, Reiss J,

Shintaku P, Deignan JL, Strom SP, Pearson CE, Vilain E,

Grody WW.

Genes Chromosomes Cancer. 2015 Nov 6. doi: 10.1002/

gcc.22319. [Epub ahead of print]

Joseph Kim – Fellow (Elaine F. Reed Lab)

Clonal CD8+ T Cell Persistence and Variable Gene Us-

age Bias in a Human Transplanted Hand.

Kim JY, Balamurugan A, Azari K, Hofmann C, Ng HL,

Reed EF, McDiarmid S, Yang OO.

PLoS One. 2015 Aug 19;10(8):e0136235. doi: 10.1371/

journal.pone.0136235. eCollection 2015. Erratum in:

PLoS One. 2015;10(12):e0146008.

Shino Magaki - Resident

Two cases of rheumatoid meningitis.

Magaki S, Chang E, Hammond RR, Yang I, Mackenzie

IR, Chou BT, Choi SI, Jen JC, Pope WB, Bell DA,

Vinters HV.

Neuropathology. 2015 Sep 8. doi: 10.1111/neup.12238.

[Epub ahead of print]

Meghan Pearl – Resident

Accelerated rejection, thrombosis, and graft failure with

angiotensin II type 1 receptor antibodies.

Pearl MH, Leuchter RK, Reed EF, Zhang Q, Ettenger

RB, Tsai EW.

Pediatr Nephrol. 2015 Aug;30(8):1371-4. doi: 10.1007/

s00467-015-3123-5. Epub 2015 May 9.

Jennifer Woo - Resident

Histologic examination of decellularized porcine intesti-

nal submucosa extracellular matrix (CorMatrix) in pediat-

ric congenital heart surgery.

Woo JS, Fishbein MC, Reemtsen B.

Cardiovasc Pathol. 2016 Jan-Feb;25(1):12-7. doi:

10.1016/j.carpath.2015.08.007. Epub 2015 Aug 28.

SungEun Yang- Current Fellow (Jian Yu Rao Lab)

Has Afirma gene expression classifier testing refined the

indeterminate thyroid category in cytology?

Yang SE, Sullivan PS, Zhang J, Govind R, Levin MR,

Rao JY, Moatamed NA. Cancer Cytopathol. 2015 Sep 30. doi: 10.1002/cncy.21624.

[Epub ahead of print]