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1 NEW DELHI TUBERCULOSIS CENTRE ANNUAL REPORT 2016 - 2017 JAWAHARLAL NEHRU MARG, NEW DELHI-110002 Phone : Enquiry : 23234270, Office : 23239056 Fax : 23210549 e-mail : [email protected], [email protected] Website : www.ndtbc.com

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Page 1: ANNUAL REPORT · 2018-06-08 · NEW DELHI TUBERCULOSIS CENTRE ANNUAL REPORT 2016 - 2017 JAWAHARLAL NEHRU MARG, ... CONTENTS ANNUAL REPORT 2016-2017 Page No. Message from Chairman

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NEW DELHI TUBERCULOSIS CENTRE

ANNUAL REPORT

2016 - 2017

JAWAHARLAL NEHRU MARG, NEW DELHI-110002

Phone : Enquiry : 23234270, Office : 23239056

Fax : 23210549

e-mail : [email protected], [email protected]

Website : www.ndtbc.com

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CONTENTS

ANNUAL REPORT

2016-2017

Page No.

Message from Chairman 4

From Director’s Desk 5

About the Institute 7

Managing Committee 8

Scientific Advisory Committee 9

Ethical Committee 10

Senior Staff Members 11

Research and Publications 12

Participation in Scientific Events 30

Meetings 49

Clinical Section 50

Epidemiological Section 53

Public Health Section 56

Mycobacterium Laboratory 62

Training and Monitoring Section 68

Supervisory Activities 86

Library and Information Services 87

Administration 88

Summary of activities of New Delhi TB Centre 91

Annual Accounts 93

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As one of the oldest organization, New Delhi

Tuberculosis Centre since its inception in 1940

has a history of magnificent journey and growth

to achieve its present stature. Today it holds a

place of pride amongst the National level

institutes serving the patients with TB and other

respiratory diseases. It is a matter of immense

pleasure and satisfaction for me to be associated

with this Institution..

In recognition of its expertise in the areas of TB

research, training and programme implementation, it has been

designated as State TB Training and Demonstration (STDC) center

and Intermediate Reference Laboratory (IRL) under RNTCP for the

state of Delhi to monitor RNTCP activities and Designated Microscopic

Centers of Delhi state. It is the first STDC to start performing the

base line DST of all MDR cases for second line anti TB drugs and

planning to do universal DST for all smear positive cases, diagnosed

in the state.

The institute is providing necessary support to State TB Cell in

enhancing the notification of TB cases in Delhi by public as well as

private institutes. It is actively participating as a state partner in Active

Case Finding (ACF), a strategic national activity under RNTCP.

I extend my heartiest congratulations and wish that the institute

expand, diversify and flourish more and more to impart quality health

services to TB patients. I am grateful to Ministry of Health & Family

Welfare, GOI, Central TB Division and Government of Delhi for

extending their support to the Institute. I express my heartiest

gratitude and appreciation to the learned faculty, technical staff and

all employees for their constant cooperation and efforts towards

building this center as a national Institute.

Dr. L.S. Chauhan

Chairman

Message from Chairman

Dr. L.S. Chauhan

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Today, it is a matter of pride for me to represent

the annual report of glorious institute ‘New Delhi

Tuberculosis Centre’ who is giving full support

in journey to end the deadly disease. The Centre

which was established in 1940 as a ‘Model TB

Clinic’ has completed 76 years of its journey and

now grown up as a full fledged institute indulged

not only in clinical and diagnostic fields, it has

also established its role in RNTCP monitoring

and operational research in field of TB and

respiratory diseases. The report presents the summary of different

activities of the centre during the year.

When NTP started in India, NDTB Centre was one of the ten chest

clinics in Delhi. After introduction of RNTCP, in 1997 it became one

of the chest clinic of Delhi rendering DOTS services to half a million

of population of walled city of Delhi. Since then we have progressed

to become State TB Training & Demonstration Centre (STDC) as well

as Intermediate Reference Laboratory (IRL) for Delhi State providing

monitoring activities for DOTS and diagnostic services under RNTCP

for whole of Delhi State.

Patient care remains one of the basic activities of the Centre. During

the year, more than 10000 patients attended the OPD department of

the Centre for opinion and treatment. The doctors and staff of the

Clinical Section provide their service to the patients and after

diagnosing their disease, the patients are referred to their respective

areas for treatment. DOT Centre in its complex also put 455 patients

on treatment.

The laboratory of the Centre is equipped with all the newer diagnostic

techniques and is functioning as Intermediate Reference Laboratory

where we receive samples from 17 chest clinics of Delhi and providing

Dr. K.K. Chopra

From Director’s Desk

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its services for Line Probe Assay, solid and liquid culture and DST.

Epidemiology section of New Delhi Tuberculosis centre is involved in

various activities. Every year, the radiological examination of

employees of various organizations is done by the section. The faculty

of the section is also involved in running operational research projects.

The Centre is also engaged in teaching and training activities. The

interns and post graduate medical students of MAMC and V.P. Chest

Instituted are posted for teaching and training here. The Centre

runs a TB Supervisor Course in addition to the training of nursing

students from Ahilaya Bai College of Nursing, RML Hospital and Lady

Reading Health School.

This year, ECHO-MDR distance learning project is started in Delhi

State. The objective of the project is to build the capacity of Health

Service provider. Under this project, STDC, STO office, DRTB centers

and DTOs come together in virtual platform to discuss about various

issues, present cases and learn through didactic presentation by

experts. The NDTB Centre has participated in the project actively.

The staff of the centre is actively involved in conducting research

activities in clinical, bacteriological and programme related aspects.

During the year seven papers were published in journals

The details of the Centre’s activities are presented in the report. I am

grateful to the Ministry of Health & Family Welfare and Central TB

Division for the financial support. I am grateful to all the members of

Managing Committee, State TB Control Officer Delhi State and TB

Association of India for valuable help and cooperation for strengthening

the infrastructure at New Delhi Tuberculosis Centre.

Dr.K.K.Chopra

Director

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Established in 1940 as a Model TB Clinic, NDTB Centre has

now grown into a fully National level institute for TB and Chest

Diseases. The objectives of imparting health care, training and

education are being met in an integrated form here. In 1951, it was

upgraded to be the first TB demonstration cum Training Centre with

the assistance of WHO, UNICEF & Government of India. In 1966 it

became a referral Centre and was designated as State TB Training &

Demonstration Centre for the State of Delhi in the year 2005. Today

it has become a reality, as the Centre has gained due recognition

nationwide for excellence in the treatment of TB and respiratory

disease. The Government has supported both technically and

financially to make it an apex institute in the country.

With the objective of expansion of quality DOTS services to the entire

country, the Centre continues to render the services in the field of

TB and Respiratory diseases. The Centre aims at widening sources

both in terms of activities and access, and to sustain the achievements

for decades to come in order to achieve ultimate objectives of TB

control in the country. It is also actively participating in the National

level programme for finding TB cases under “Active TB Case Finding”

with Delhi TB State cell.

The Centre actively works in liaison with State TB cell on getting

positive results for all components of a new Stop TB Strategy. As an

IRL, the institute assists RNTCP in maintaining the global standards

through quality assurance for the laboratory in the state. The Institute

has been a guiding force in formulating policy in relation to

involvement of Private sector and Medical Colleges in the programme

for the management of pediatric TB and operational research along

with other various TB related research topics for more than 75 years.

ABOUT THE INSTITUTE

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MANAGING COMMITTEE

1. Dr. L.S. Chauhan ChairmanVice- ChairmanTuberculosis Association of India

 2. Dr. V.K. Arora Member

Financial AdviserNew Delhi TB Centre/Vice Chairman (Research and Publication)Tuberculosis Association of India 

 3. The Additional Secretary & FA Member

Ministry of Health & Family welfare   4. The Joint Secretary (Health) Member

Ministry of Health & Family Welfare  5. The Deputy Director General (TB) Member

Central TB Division 6. Director Member

National Institute of TB & RespiratoryDiseases  

 7. The Director Member

VP Chest Institute  8. The Director of Health Services Member

Delhi Administration  9. Director Medical Services Member

New Delhi Municipal Committee  10. Honorary General Secretary Member

Delhi Tuberculosis Association   11. The Executive Director Member

Indian Railways   12. Secretary General Member

Tuberculosis Association of India                                        13. Director Member Secretary

New Delhi TB Centre 

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Dr. L.S.Chauhan Chairman

Chairman

New Delhi Tuberculosis Centre

Dr.Ashwani Khanna Member

State TB Officer

Delhi State

Director Member

V P Chest Institute

Dr. Varinder Singh Member

Professor – Pediatric, Kalawati Hospital

Lady Harding Medical College

Shri G.P. Mathur Member

Ex-Statistician

New Delhi Tuberculosis Centre

Dr. M. Hanif Member

Bacteriologist

New Delhi Tuberculosis Centre

Dr. Nishi Aggarwal Member

Statistician

New Delhi Tuberculosis Centre

Dr. K.K.Chopra Member Secretary

Director

New Delhi Tuberculosis Centre

SCIENTIFIC ADVISORY COMMITTEE

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Director ChairmanVP Chest Institute

Dr. Sanjay Rajpal MemberChest PhysicianNew Delhi Tuberculosis Centre

Dr. M. Hanif ,K.M. MemberBacteriologistNew Delhi Tuberculosis Centre

Dr. Nishi Aggarwal MemberStatisticianNew Delhi Tuberculosis Centre

Dr. Chinkholal Thangsing MemberNGO – HIV Expert

Shri T.S. Ahluwalia MemberSecretary GeneralTuberculosis Association of India

Prof. Mala Sinha MemberFaculty of Medical ScienceDelhi University

Mr. Swetaketu Mishra MemberAdvocate

Dr. M. M.Singh MemberProfessorMaulana Azad Medical College

Shri G.P. Mathur MemberEx-StatisticianNew Delhi Tuberculosis Centre

Sh. Madan Mohan MemberDelhi TB Association

Sh. Sanjeev Gupta MemberCommunity Person

Dr. Shanker Matta Member SecretaryEpidemiologistNew Delhi Tuberculosis Centre

ETHICAL COMMITTEE

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Dr. K. K. Chopra Director

M.B.B.S., M.D., D.T.C.E.

Dr. Sanjay Rajpal Chest Physician

M.B.B.S., D.T.C.D., F.N.C.C.P.

Dr. Mahmud Hanif Bacteriologist

Ph.D.

Dr. Nishi Aggarwal Statistician

Ph.D.

Dr. Shanker Matta Epidemiologist

M.B.B.S., M.D.

Dr. Shivani Pawar Medical Officer

M.B.B.S., D.T.C.D.

Mr. D.C. Uppadhyay Administrative Officer

B.Com.

SENIOR STAFF MEMBERS

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Research papers published.

During the year 2016-17, the following research papers have been

published or submitted by faculty of the Centre:

1. Band pattern Analysis of mutations in Rifampicin resistance

strain of Mycobacterium tuberculosis by Line Probe Assay

in patients from Delhi, India. Himanshu Vashistha,  M. Hanif, K.K. Chopra,  A Khanna, D Shrivastava Indian Journal of

Tuberculosis, Vol.63, Issue 3;2017.

2. Rapid detection of multi drug resistance among multi drug

resistant tuberculosis suspects using line probe assay. Manoj

Kumar Dubey, U Bhardwaj, M. Hanif, K K Chopra, A Khanna,

S Saini, K K Dwivedi, H Vashishtha, Z Sidiq, V Ahmad, S Sharma

Asian Journal of Pharmaceutical and Clinical Research, Vol

10, Issue 1, 2017, 131-133

3. Baseline Resistance to Ofloxacin and Kanamycin Among

Multi-Drug Resistant Strains of M. tuberculosis Isolated at

an Intermediate Reference Laboratory in Delhi. Vasim Ahmad,

D Srivastava, M Hanif, Z Sidiq, K K Dwivedi, H Vashishtha, S

Sharma, S Saini, V K Bediraddy, K K Chopra, A Khanna Indian

Journal of Applied Research, Volume: 6, Issue: 8, August 2016

(586-588)

4. Molecular Line Probe Assay for the Detection of Multi Drug

Resistant Tuberculosis and Comparison of Results with

Conventional Solid Culture and Drug Susceptibility Testing.

Manoj Kumar Dubey, U Bhardwaj, M. Hanif, K K Chopra, A

Khanna, K K Dwivedi, H Vashishtha, S Saini, Z Sidiq, V Ahmad,

S Sharma Indian Journal of Applied Research, Volume: 6, Issue:

8, August 2016 (643-645)

RESEARCH AND PUBLICATIONS

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5. Rapid detection of extensively drug-resistant (XDR-TB)

strains from multidrug-resistant tuberculosis (MDR-TB) cases

isolated from smear-negative pulmonary samples in an

Intermediate Reference Laboratory in India. Himanshu

Vashistha, M. Hanif, S Saini, A Khanna , S Sharma, Z Sidiq, V

Ahmad, M K Dubey, K K Chopra, D Shrivastava Indian Journal

of Tuberculosis, Vol. 6 3 (2016) 1 46 – 150

6. Meso level multi – disciplinary approach for reduction of

initial defaulters in Revised National Tuberculosis

Programme, Delhi, India. Nandini Sharma, Meera Dhuria,

Nishi Aggarwal and K.K. Chopra, Paper accepted in Indian

Journal of Tuberculosis.

7. Newer Rapid Diagnostic Methods in MDR TB case

management. Himanshu Vashistha, M. Hanif and K.K. Chopra,

article published in 67 th TB seal campaign 2016. The

Tuberculosis Association of India.

Research papers presented in Conference

The 71st National Conference on Tuberculosis and Chest

Diseases was organized by Tuberculosis Association of Union

Territory, Chandigarh under the aegis of TB Association of India

at Department of Pulmonary Medicine PGI Chandigarh from

16th – 18th December, 2016. Dr. K.K. Chopra, Director and Dr.

M. Hanif, Bacteriologist NDTB Centre attended the conference.

Following research papers were presented in the conference:

1. Retesting by line probe assay of samples initially identified by

CBNAAT as MDR-TB

2. Recovery of M. Tuberculosis isolates from compromised sputum

specimens: a study of drug resistance pattern

3. Phenotypically confirmed XDR strains among MDR cultures

with uncommon mutations in rpob gene

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4. Efficiency of Genotype MTB DR plus in accurately identifying

Mycobacteria other than tuberculosis (MOTT) in clinical samples

5. Diagnosis of Multi Drug Resistant Tuberculosis by Line Probe

Assay and comparison with conventional culture and drug

susceptibility test

6. Comparison of liquid culture DST with LJ culture DST for

second line drugs Ofloxacin and Kanamycin among multi-drug

resistant strains of M. tuberculosis isolated at an intermediate

reference laboratory in Delhi

Research Projects

1. A multicentre study of diagnostic accuracy and feasibility

of the Xpert Ultra for detection of TB and Rifampicin

resistance in adults suspected of having pulmonary TB

The Xpert MTB/RIF (Xpert) assay, th e first near-patient test

for tuberculosis (TB), detects Mycobacterium tuberculosis (Mtb)

with a limit of detection (LOD) of 133 CFU/ml sputum, and

detects mutations in the Mtb rpoB gene which cause Rifampicinresistance (RIF-R). However, despite high sensitivity overall,

Xpert sensitivity is only 60 – 80% in smear-negative TB. Also,

small numbers of false RIF-R have been reported recently,usually due to abnormal real-time PCR curves or miss-

identification of RIF-susceptible (RIF-S)

synonymous rpoB mutants as RIF-R. A new molecular TB testwith an LOD equivalent to the 10 – 100 CFU/ml LOD of liquid

culture and improved RIF-R detection is needed. Thenew Ultra assay is much more sensitive than Xpert, and is likelyto be as sensitive as liquid TB culture. Ultra detects RIF-R asefficiently as Xpert; but the specificity of Ultra RIF-R is likelyto be higher due to improvements in assay design.

The Ultra assay should significantly increase TB detection insmear-negative patients and provide more reliable RIF-Rdetection.

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FIND Geneva is leading an eleven-site, eight-country study in

partnership with the TB clinical diagnostic research consortium

to assess the accuracy and feasibility of the Xpert Ultra test in

adults suspected having pulmonary TB. In case of India, ultra

study was initiated at NDTB, New Delhi along with few other

sites which were geographically different. Two of the primary

objectives of the study was to estimate and compare the

sensitivity and specificity of the Ultra versus the standard Xpert

MTB/RIF test for the detection of culture-positive pulmonary

TB and for Rifampin resistance detection compared to the optical

phenotypic drug susceptibility testing.

The project was funded by FIND Geneva and it started from

March 2016 and completed on March 2017. All the objectives

were fulfilled and the results obtained in the study have been

submitted to FIND Geneva.

2. Accelerating TB Notification from the private health sector

in Delhi, India.

The project has been completed during 2016-17 and report

has been submitted to Delhi State TB Cell. The study showed

that there was a significant improvement in TB case notification

from the private sector and provided them NIKSHAY login for

future notification of tuberculosis cases from their set-up as

per RNTCP guidelines.

3. SMS for sure project

SMS for sure project was undertaken by NDTB with the aim of

assessing the impact of SMS on TB treatment adherence. For

this project an IT company was employed by the name of Shreya

Web Solutions. The aim of this project is to see whether SMS

has any role in decreasing default rates among TB patients.

Activities undertaken and outcomes till date:

· In the month of October 2015, 239 DOT providers were trained

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in 8 batches .It was a one day training programme whereby

they were explained about their role in the project.

· DTOs of all districts were sensitized during quarterly meet.

· A server was installed at NDTB in the month of October and

the activity was pilot tested in first few days.

· A toll free number has been initiated for the benefit of DOT

providers.

· The process: 6000 newly diagnosed patients were randomized

into 3 groups by the server. Group 1 would received enrolment

conformation SMS, weekly motivational SMS and a reminder

SMS, as and when they missed a dose. Group 2 patients received

enrolment conformation SMS, a reminder SMS when they

missed a dose. Group 3 patients were not received any SMS

except the study enrolment conformation SMS.

· The project was formally initiated from 2nd November 2015. A

server was installed as mentioned earlier, at NDTB centre and

2 counsellors were hired by the IT company to telephonically

address all queries of DOT providers.

• Outcome: The project is ongoing and 6000 patients were

enrolled on 7th July 2016.Data on missed doses by patients is

being compiled on the server. The results of 6000 patients

registered in July 2016 ( November 2015-July2016)is as follows:

(Updated as on 31st March 2017)

Group 1: 2000

Group 2:2000

Group 3 :2000

Total No. of  Missed Doses : 87

Total No. of  Default : 83

Total No. of Patient Died : 43

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Total number of “Failure : 32

Total No. of patients who have

successfully completed treatment : 2178

Transferred out : 22

Total : 2445

*Outcome of patients are awaited

It was decided that analysis would be undertaken for the period

from 2nd November 2015 to 7th July 2016. Hence Patients

registered between 2nd November 2015 till 7th July 2016, whose

outcome were available would be included for analysis.

4. Framework of TB care in prisons

A project titled “Framework of TB care in prisons” is being

managed by NDTB and the State TB Cell. Aim of this project is

to estimate the burden of TB among prison inmates at Tihar

Jail, frame the operational modalities for early detection of TB

and drug resistant TB at Tihar Jail. Lastly, to mobilize

standardized TB care practices among the jail inmates (during

their stay in prisons and adequate referral thereafter). Talks

are on with the Tihar jail officials to take up this project

5. TB case finding activities at night shelters of Delhi

New Delhi Tuberculosis Centre was involved with the aim the

sensitization programme for Care Takers of Night Shelter with

the objective of identifying TB suspects coming to stay at night

shelters of Delhi. NDTB is planning to undertake this project.

Aim of this project is to ensure that staff of night shelters is

trained as DOT providers so that they can identify TB suspects

and who are further referred to the nearby chest clinic for

treatment. Long term objective is to open DOT centres in some

of the night shelters.

In this regard a meeting was held on 25th April 2016 at NDTB

Centre to discuss modalities about sensitization programme

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for care takers of night shelter. Staff from Epidemiology section,

NDTB, District TB officers, WHO consultant and representative

from Delhi TB Association were involved. The care takers and

supervisors were sensitized about symptoms, diagnosis,

treatment and prevention of TB. IEC material and sputum cups

were also provided to all night shelters. Three teams were

identified to train staff of all districts by three teams of NDTB

Centre, Delhi TB Association and Lok Nayak Chest Clinic. 22

chest clinics were identified which had night shelters in their

district. Visits were undertaken from May 2016 to July 2016

for all the 22 districts. Every team had to conduct at least one

sensitization programme once a week in their chest clinic on

every Friday by using any method i.e. flip chart, presentation

slides and lecture method etc. In every district, MOTC, STS

and NGO representative were involved to conduct and coordinate

the activity.

The sensitization was successfully imparted to staff of night

shelters in all the districts. After this activity, every district is

regularly reporting the TB cases put on treatment among

inmates of night shelters in their monthly report. Care takers

have also been trained to act as DOT providers for TB cases

detected in their night shelters.

6. Accelerating access to quality TB diagnosis for pediatric

cases.

This was started with efforts of RNTCP and FIND at New Delhi

Tuberculosis Centre. Under this initiative, FIND have setup high

throughput molecular lab at our site, catering exclusively to

the TB diagnostic needs of pediatric population. This study

provides accurate evidence based on same day diagnosis in

line with internationally accepted standards of TB care with no

cost to patient or provider both in private and public sector.

This diagnostic option has been introduced at the existing

RNTCP labs for the processing of pediatric specimens such as

sputum, gastric lavage, BAL, induced sputum, lymph node

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aspirated, etc. for use in Xpert MTB/RIF. Such an effort came

as a big financial relief to poor patients and obviating the

necessity to visit private labs and related huge costs.

All pediatrician both in public and private sector in the city

referred pediatric suspects to our laboratory. The specimens

were tested on the same day and the results communicated to

referring provider electronically (E-mail and SMS) and

simultaneously notified to RNTCP under Nikshay.

Overall 13,363 pediatric patients were tested between April 16

to March 17 under this project, out of which 2570 were non-

respiratory specimens. The project has demonstrated the

feasibility of extending Xpert test to non-sputum specimens

from children with a very high proportion of interpretable results

with more than a threefold increase in TB case detection over

smear microscopy and detection of significant number of

rifampicin resistant TB cases. The project has also shown the

utility of offering up front Xpert testing to pediatric presumptive

TB and DR-TB patients under programmatic conditions.

CBNAAT Performance:

Project: Accelerating access to quality

TB diagnosis for Pediatric Cases

(For the period from April 2016 to March 2017)

Total number of tests performed 13109

Total number of MTB not detected 11682

Total number of MTB detected and RIF sensitive 1136

Total number of MTB detected and RIF resistant 191

Number of Invalid test 100

Total number of EP-TB sample processed 2570

Total number of MTB detected and RIF sensitive 283

Total number of MTB detected and RIF resistant 80

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Type of specimen received and X-pert results from

April 2016 to March 2017

Type of Specimen No. of Xpert Positivity

Specimen Positive (%)

Abscess 11 3 27

Ascitec Fluid 142 3 2

BAL 392 55 14

CSF 1162 84 7

ET secretion 32 5 16

FNAB 82 28 34

Gastric Aspirate 7875 529 7

Gastric Lavage 66 4 6

Induced Sputum 82 13 16

Lymph Node 177 86 49

Pericardial Fluid 25 3 12

Pleural Fluid 652 32 5

Pus 379 156 41

Sputum 2009 322 16

Tracheal Aspirate 23 4 17

Grand Total 13,109 1,327

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MD/MS/DNB Thesis being conducted in collaboration

1. Clinical correlates of drug sensitivity pattern in children with

tuberculosis : A cross sectional study

(MD Thesis of PG student of Department of Pediatrics, Lady

Harding Medical College,)

The burden of childhood tuberculosis (TB) reflects the ongoing

TB transmission in a community. About one million children

fall sick with TB every year. It is seen that the pattern of drug

resistance in children of a community generally mirrors that of

the adult population. Children rarely have acquired resistance

because childhood TB is usually paucibacillary with small

organism load. Hence it is unlikely that resistant mutants will

occur and be selected. Childhood TB can be used as a sentinel

marker to evaluate the effectiveness of a TB control programme.

Surveillance of drug resistance is therefore essential because

trends in primary drug resistance or initial drug resistance

provide an indication of the effectiveness of the treatment

regimen while drug resistance rate in patients with a history of

previous treatment can indicate failures in the management of

the disease. It is evident from the literatures that there is paucity

of information on drug sensitivity pattern of isolates from

children with TB especially in India. So the present study is

being carried out to observe pattern of drug sensitivity and

emerging drug resistance in children with TB. Children between

0-14 years of age diagnosed with TB (free from known

immunodeficiency and serious illness) are being included in

the study. Mycobacteriological examination like Xpert MTB Rif,

Line Probe Assay and MGIT Culture and DST will be done.

Result generated will help in understanding pattern of

sensitivity and resistance in children suffering from TB so that

better and timely treatment management can be offered and

understood.

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2. A study of the course of illness in children with

extrapulmonary tuberculosis on standard chemotherapy

(MD Thesis of PG student of Department of Pediatrics, Lady

Harding Medical College,)

Childhood tuberculosis (TB) accounts for 10 – 20% of all TB

cases in high burden cases. The most common form of

tuberculosis is pulmonary i.e. about 60-80% cases and rest

20-40% account for extrapulmonary TB (EPTB). The most

common form of EPTB is lymph node. Other site of

involvement includes central nervous system, abdominal,

skeletal, etc. The problem in EPTB lies in diagnosing the

cases and thereafter follow-up the cases to assess end point

of cure. Symptom resolution is highly variable in all forms of

EPTB and most of the understanding about the disease course

comes from earlier studies on the natural history of disease.

The exact pattern, timing of symptom response to modern

day therapy and microbiological/ radiological improvement

in patients after first time exposure to therapy especially in

Indian setting is less clearly stated in the available literatures.

Studies that have evaluated the course during treatment are

old enough when the drug regimens used were entirely

different from modern day chemotherapy. So the present

study was designed to study the course of illness in children

with EPTB on standard chemotherapy. 75 children above 06

months and upto 18 years of age with newly diagnosed EPTB

were included in the study. Diagnostic tests like Xpert MTB

Rif and MGIT Culture and DST were done during the course

of treatment. Results generated from the study are under

analysis.

3 To study the role of Cartridge Based Nucleic Acid

Amplification Test (CBNAAT) in early diagnosis of pulmonary

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tuberculosis and primary drug resistance in HIV positive

patients

(MD Thesis of PG student of Department of Medicine, PGIMER,

Dr. Ram Manohar Lohia Hospital)

Tuberculosis (TB) and Human Immunodeficiency Virus (HIV)

have been closely linked since the emergence of AIDS. The

lifetime risk of TB in immunocompetent persons is 5% to 10%,

but in HIV positive individuals, there is a 5% to 15% annual

risk of developing active TB disease. Studies have shown that

pulmonary TB (PTB) in HIV positive patients remains the most

common opportunistic infection in India ranges from 17% to

23%. Sputum microscopy in HIV positive patients is found to

be less reliable in diagnosis of TB. Further, increasing number

of patients with drug resistant tuberculosis (DR-TB) creates

more challenges in its treatment. Conventional diagnosis of

DR-TB relies on bacterial culture and drug susceptibility

testing, a slow and cumbersome process. Thus, it is very

important to identify PTB at an earliest so that it can be

managed appropriately. Cartridge Based Nucleic Acid

Amplification Test (CBNAAT) is one of a recently developed

diagnostic modality which can simultaneously detect TB and

perform drug susceptibility testing of one of the key drug –

Rifampicin within few hours. So, the present study was carried

out to study role of Cartridge Based Nucleic Acid Amplification

Test (CBNAAT) in early diagnosis of pulmonary tuberculosis

and primary drug resistance in HIV positive patients. 100 HIV

positive subjects greater than 18 years of age presented with

symptoms/ x-ray suggestive of TB were included in the study.

Mycobacteriological examination like Xpert Rif and MGIT

Culture of all the subjects were done. Results generated are

under analysis.

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4. Comparison of Line Probe Assay with conventional solid

culture and drug susceptibility testing to detect multi drug

resistant tuberculosis

(Ph.D Thesis submitted at Maharaj Vinayak Global University,

Jaipur)

The global threat of multidrug-resistant tuberculosis (MDR-

TB) to TB control, underscores the importance of prompt and

rapid identification of such resistant strains. Isoniazid and

Rifampicin are the key first line anti-tuberculosis drugs and

resistant to these drugs is likely to result in treatment failure

and poor clinical outcomes. As per an estimate, India has the

largest number of MDR-TB cases amongst notified TB patients

of any country.

Newly developed molecular based methods have advantages

over conventional phenotypic methods in terms of both accuracy

and turnaround time. The genotype MTBDR plus assay is

commercially available. Line Probe Assay from Hain life

sciences, Germany is designed to detect most important gene

mutations conferring resistance to Isoniazid and Rifampicin.

Although this assay has been studied in several laboratories,

there is wide variation in circulating M. tuberculosis strains

across the globe. Hence in this study, it was attempted to

evaluate the performance of LPA for the rapid detection of MDR

TB. The results of this molecular method was compared with

that of the conventional phenotypic drug susceptibility to

demonstrate the sensitivity, specificity and accuracy of LPA with

its capacity to shorten the time required for TB diagnosis

compared to that of conventional method.

5. Rapid screening of second line anti tuberculosis drugs

resistance among MDR TB suspects by Liquid DST (MGIT

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960) and comparative evaluation with Solid Proportion

Method.

(PhD thesis of student, Department of Life Science, Jaipur

National University, Jaipur,)

Rapid and accurate diagnosis of the Mycobacterium

tuberculosis and its drug susceptibility pattern, is essential for

timely initiation of treatment and ultimately, control of the

disease. The importance of diagnosing XDR-TB among MDR-

TB has been the driving force behind this study, more rapidly

XDRs can be detected among multi drug resistant patients.

This will lead to more rapid implementation of the best therapy

for given patients. Therefore this study was initiated with the

objectives, a) Screening of Kanamycin and Ofloxacin resistance

in suspected MDR TB patients by Liquid DST method (MGIT

960) and Standard proportion method (Solid LJ DST), b)

Comparison of sensitivity and specificity of Liquid DST (MGIT

960) for Kanamycin and Ofloxacin with Standard proportion

method (Solid LJ DST), c) Evaluation of Diagnostic accuracy of

both the methods in discordant results for the detection of

XDR-TB, d) Detection of mutations imparting discordant

resistance by DNA sequencing. In this study, all patients were

subjected to sputum-smear microscopy for acid-fast bacillus

(AFB) by fluorescence microscopy. All sputum smear positive

specimens were tested for primary drug susceptibility by Line

Probe Assay (LPA) method while sputum negative samples were

directly cultured on MGIT system and when culture become

positive these samples subjected to LPA. Diagnosed MDR

specimens subjected to culture on MGIT 960 and Lowenstein-

Jensen (L-J) slopes. All positive culture were further tested for

drug susceptibility testing (DST) by MGIT 960 as well as by LJ

proportion method for two drugs namely ofloxacin and

kanamycin. Study is under process.

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6. Genetic Polymorphism of rare mutations in rifampicin

resistance of Mycobacterium tuberculosis infected patients.

(PhD thesis submitted to School of Life Sciences at Jaipur

National University, Jaipur,)

The multidrug-resistant TB (MDR-TB) crisis continues, with an

estimated 480 000 new cases in 2013. Genetic polymorphism

is the occurrence of two or more alleles at one locus in the

same population, and each with appreciable frequency. It is

therefore equally important to identify the genetic origins of M.

tuberculosis inter strain pathobiological differences in order to

progress the eventual association of strain genotypes with

patient clinical phenotypes. Several studies showed frequency

of mutations outside RRDR region (hot spot) and it is also

present in Indian M. tuberculosis isolates but their role and

impact in polymorphism is not yet well studied. Therefore, in

the present study we attempted to rapidly screen drug

resistance among smear positive sputum samples by the use of

LPA in Delhi region. The results of the molecular diagnostic

method was compared with that of the phenotypic drug

susceptibility test (MGIT 960 DST) to demonstrate the

sensitivity, specificity and accuracy of LPA with its capacity to

shorten the time required for TB diagnosis compared to that of

the phenotypic DST method. The virulence of Mycobacterium

tuberculosis and its genetic polymorphism prevalence in clinical

isolates was studied through band pattern analysis in DNA

strips of Line Probe Assay. DNA Sequencing was performed to

confirm the mutations reported in this study which also

confirmed Novel mutations. The technique described in our

study may prove to be useful for identifying MDR-TB. The

presence of uncommon mutations confirms genetic

polymorphism that may require treatment targeted at both

drug-resistant and drug-susceptible phenotypes for the better

management of patients with MDR-TB.

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7. Diagnosis of MDR & XDR-TB in Smear Negative pulmonary

and Extra pulmonary specimens from drug resistant TB

suspects

(Ph.D thesis of student Maharaj Vinayak Global University,

Jaipur)

The emergence and spread of multidrug-resistant tuberculosis

(MDR-TB) and extensively drug resistant tuberculosis (XDR-

TB) are a major medical and public problem threatening the

global health. A lot of work has been done on smear positive TB

patients but sparse data is available on smear negative cases.

Due to low mycobacterial load in early stage of infections, such

patients are declared as smear negative even though they are

actually positive. Such patients continuously spread infection

in their close vicinity. Recovery of mycobacterium from such

smear negative TB patients and the pattern of drug sensitivity/

resistance observed in these cases can help in better

management of these cases. Therefore, this study was initiated

with the aim to determine the recovery of M. tuberculosis in

smear negative samples through liquid culture using MGIT 960

and also to determine the number of drug resistant cases

through Line Probe Assay. DST for second line drugs using

MGIT was planned once culture positives were observed.

Though intake of samples and the testing have been completed

the data analysis is under process. This data on diagnose of

drug resistance in smear negative and culture positive cases is

very important.

8. Diagnosis of Multidrug Resistance Tuberculosis among

suspects using molecular Line Probe Assay

(M.Sc dissertation submitted at Jaipur institute of

Biotechnology, Maharaj Vinayak Global University, Jaipur)

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Globally, tuberculosis (TB) cases continue to be on the rise

despite aggressive public health interventions. India bears a

quarter of world’s tuberculosis burden and has the highest

number of newly diagnosed cases annually. Drug resistant TB

is the most important factor that threatens to disrupt the gains

achieved in tuberculosis control. A prolonged time of diagnosis

of six to eight weeks taken by the conventional culture and

DST leads to the patients being treated with an inappropriate

drug regimen, which results in the selection of drug resistant

mutant strains and their continuous spread in the community.

Many rapid methods have been developed to address this issue.

A Genotypic method exploits the fact that MDR arises due to

random mutations, mainly found in rpoB, katG and inhA. Line

probe assay (LPA) is one of the rapid molecular methods which

are used for the screening and diagnostic for pulmonary

tuberculosis. Therefore, this study was conducted using LPA

for the diagnosis of MDR-TB among the MDR-TB suspects.

Smear positive subjects were subjected to DNA extraction,

followed by amplification and development of blot by reverse

hybridization. The data obtained correlate well with earlier

reports from other studies.

9. Isolation of Mycobacterium from smear negative multidrug

resistant TB suspects using liquid culture (MGIT 960)

(M.Sc dissertation submitted at Jaipur institute of

Biotechnology, Maharaj Vinayak Global University, Jaipur)

Acid fast staining of clinical material, followed by smear

microscopy remains the most frequently used microbiological

test for detection of TB. The major drawback of sputum smear

microscopy is its poor sensitivity. Also drug susceptibility status

cannot be ascertained from smear microscopy. Culture of M.

tuberculosis in clinical specimens is substantially more sensitive

than smear microscopy. Culture can be performed using solid

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media such as Lowenstein- Jensen or liquid media such as that

used in commercially available automated systems. A major

drawback with LJ culture method is that it is time consuming.

On the other hand, liquid culture based methods have shorter

TAT. The MGIT 960 system (supplied by BD) is currently

recommended by WHO as well as RNTCP. Therefore, this study

was initiated with the objective: To isolate Mycobacterium

tuberculosis from specimens collected from sputum smear

negative MDR-TB suspects using liquid culture (MGIT 960) and

to compare both techniques: liquid culture (MGIT) and solid

culture (LJ medium) with regard to Mycobacterium tuberculosis

isolation. Sputum samples collected at DMC level were

transported to IRL. Smears were prepared, stained by auramine

and were examined under the microscope as per RNTCP

guidelines. All smears declared as negative were further processed

for liquid as well as solid culture. At the end of the study, the

results were compared and good correlation was observed

between both the methods. Positive growth was observed much

early in liquid culture when compared with LJ culture.

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PARTICIPATION IN SCIENTIFIC EVENTS

1. Review meeting of notification project was held on 9th April

2016 in New Delhi TB Centre. Six health workers of the project

posted in the districts attended the meeting. The record of the

visits made by them to private practitioners and laboratories

were reviewed and further guidelines for working finalised.

2. Workshop to review roll out of Bedaqueline in Delhi state with

The Union was conducted on 19th April 2016 in New Delhi TB

Centre. Representative from The Union – State TB Cells, two

project sites attended the workshop to finalise the activities to

roll out the Bedaqueline at the earliest.

3. A training workshop for coordinating sensitization of night

shelters in 25 districts was held on 25th April 2016. Three

teams of NDTBC, Delhi TB Association and Lok Nayak Chest

Clinic were trained to complete the process in two weeks.

4. One day workshop for review of “SMS for sure” project was held

on 26th April, 2016. All the DOT providers with post paid mobile

connections participated in the workshop. Reasons for low

registration in the project were reviewed and resolved. All issues

related to the project were discussed.

5. One day sensitization of DTOs was conducted in NDTB Centre

on 29th April 2016 about the newly formed schemes of PPMs.

6. A Review meeting of notification project was held on 6th May

2016. The health workers posted in six districts from the project

presented their report about notification of cases by private

practitioners and laboratories in their respective districts.

7. A CME for private practitioners under ‘TB notification’ project

was conducted on 7th May 2016 in Narela Chest Clinic. Private

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practitioners of the area were invited for the CME. Dr. K.K.

Chopra, Director delivered the lecture on TB notification which

was followed by discussion. Similar activity was conducted on

24th May 2016 in Jhandewalan Chest Clinic.

8. Delhi state RNTCP review meeting was held on 11th May 2016

in New Delhi TB Centre. Dr. K.K. Chopra, Director, STDC

presented the analysis of quarterly reports of 25 chest clinics.

Principal Investigators of different OR projects being conducted

in Delhi state presented the update on the projects.

9. Quarterly review of PMDT activities of Delhi state for 1st quarter

2016 was held on 18th May 2016 in NDTB Centre. Nodal officer

of culture DST labs and DRTB centres presented their activities

for the quarter. Issues related to newly established CBNAAT

labs and nikshay entries were discussed and appropriate

decisions were taken.

10. Sensitization programme held for 3rd year B.Sc (H) nursing

students of RAK College of Nursing on 20th May 2016 in which

they were sensitized about disease, treatment and prevention

of tuberculosis and role of nurses in care of TB patients.

11. SPYM (night shelter and drug de-addiction centre), Darya Ganj

was visited on 20 th May 2016 by Dr. Shanker Matta,

Epidemiologist and Ms. Shadab Khan, MSW to re-sensitized

the staff and volunteers working with those children. The

sensitization programme was held in form of group discussion

where participants shared their problems currently faced with

regard to TB patients and were given possible answers for their

queries.

12. Five days workshop for training of counsellors was conducted

in NDTB Centre with The Union from 23rd to 27th May 2016. A

batch of ten counsellors for MDR cases to be posted in different

parts of the country was trained during the workshop. Faculty

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of NDTB Centre, the Union and State TB Cell took lectures and

field visits during the workshop.

13. A CME for private practitioners under ‘TB notification’ project

was conducted on 24th May 2016 in Pili Kothi Chest Clinic in

which Dr. Shanker Matta, Epidemiologist delivered a lecture

on TB notification.

14. A meeting of scientific committee of RBIPMT was held on 25th

May 2016. Dr. K.K. Chopra, Director, Dr. M. Hanif,

Microbiologist and Dr. Nishi, Statistician attended the meeting

as member. Thesis protocols of DNB students were discussed

in the meeting. All the protocols were recommended after few

minor modifications.

15. A CME for members of Delhi Medical Association was organised

by The Union and State TB Department on 28th May 2016 in

DMA Hall. Dr. K.K. Chopra, Director was one of the facilitator.

He delivered lecture on TB notification and Standards of TB

care in India. About 50 doctors attended the CME.

16. Dr. Shanker Matta, Epidemiologist attended Protocol

Development Workshop from 30th May 2016 to 3rd June 2016conducted by National Institute for Research in Tuberculosis,

ICMR, Chennai.

17. A CME for private practitioners under notification project was

conducted in Shastri Park Chest Clinic on 31st May 2016. About

20 private practitioners attended the CME. Dr. Sandeep Saini,

DTO Shastri Park Chest Clinic delivered a lecture on overview

of RNTCP and Dr. K.K Chopra, Director STDC delivered a lecture

on TB notification. This was followed by discussion.

18. Regional PMDT review and planning meeting of North Zone

states was held from 8th to 10th June 2016 in Chandigarh by

Central TB Division. Delhi state was part of the review meeting.

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Dr. K.K. Chopra, Director and Dr. M. Hanif, Microbiologist were

part of Delhi state team. Dr. K.K. Chopra, Director presented

the PMDT activities of Delhi state which was followed by group

work to assess the preparedness of state for universal DST roll

out in Delhi state. It was proposed to roll out this service in

Delhi state from first quarter of 2017.

19. The Tuberculosis Association of India (TAI) proposes to adopt a

“district” and help effectively implement the RNTCP in a focused

way so that it can be made “TB free district” within a reasonable

time frame.  To start with, it has been decided to adopt districtGaya in Bihar as this is the poorest and most neglected one.

Dr. K.K. Chopra, Director was nominated as member secretary

of a central team to make Gaya (Bihar) as TB Free District. The

team was proposed by Vice Chairman, TAI and approved by

Chairman, TAI (Director General Health Services).

20. A CME was organized for private practitioners under

“Accelerating notification project” at NDMC Chest Clinic on 13th

June 2016. Twenty private practitioners attended the CME.

Dr. K.K. Chopra, Director delivered a lecture on ‘TB notification’

which was followed by discussion.

21. A meeting with representatives of ECHO India project was held

in NDTB Centre on 14th June 2016. The place and modalities

of setting up one ‘HUB’ centre at STDC under the project were

finalized. The ‘HUB’ will be used for training of DTOs and para

medical staff of RNTCP Delhi and also to review their periodical

reports.

22. On site evaluation of IRL of NDTB Centre was held from 15th

to 17 th June 2016. A team from National Reference

Laboratory visited laboratory of NDTB Centre, 3 CBNAAT sites

of Delhi and 3 DMC of Delhi for their functioning and record

keeping.

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23. Sensitization of care takers and supervisors of night shelters

under different chest clinics is being conducted. Dr. K.K.

Chopra, Director alongwith District TB Officers of respective

chest clinics discussed with staff of night shelters regarding

referral of TB suspects and to work as DOT Providers for patients

diagnosed among intimates of night shelters. The details of

visits is as under:

a) BSA Chest Clinic on 18th June 2016.

b) Ch. Desiraj Chest Clinic on 25th June 2016

c) BJRM Chest Clinic on 29th June 2016

24. Meeting of editorial board of IJT was held on 23rd June 2016 in

TB Association of India. Dr. K.K. Chopra (Director) participated

in the meeting as Associate Executive Editor of the Journal.

During the meeting, TB Seal designs for the year was discussed

and it was decided to keep ‘Dolls of India’ as TB seal design of

this year.

25. SPYM (night shelter and drug de-addiction centre), Darya Ganj

was visited on 20th June 2016 by Dr. Shanker Matta,

Epidemiologist and Ms. Shadab Khan, MSW to re-sensitize the

staff and volunteers working with those children. The

sensitization programme was held in form of group discussion

where participants shared their problems currently faced with

regard to TB patients and were given possible answers for their

queries.

26. A meeting to assess the preparedness of Delhi state for adopting

universal drug sensitivity testing for diagnosed TB cases was

held on 1st July 2016. Representatives of Central TB Division,

WHO, Delhi state RNTCP team and STDC faculty participated

in the meeting.

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27. A review meeting of health workers of TB notification project

was held on 1st July 2016. To discuss progress of the project

and further steps to be taken were reviewed.

28. A CME was organized for private practitioners under

“Accelerating notification project” at Patparganj Chest Clinic

on 5th July 2016. Twenty private practitioners attended the

CME. Dr. K.K. Chopra, Director delivered a lecture on ‘TB

notification’ which was followed by discussion. Similar CME

was also organized in Shahdara Chest Clinic on 11th July 2016.

29. The International Union Against TB and Lung (The Union)in Delhi organized a CME in collaboration with RNTCPon 09 th July,16. The theme of the CME was “Recentupdates in TB Care and Control”. Dr. K.K. Chopra, Directordelivered a lecture on “Standards of TB Care in India” during

the CME.

30. Sensitization of care takers and supervisors of night shelters

under different Chest Clinics is being conducted. Dr. K.K.

Chopra, Director alongwith District TB Officer visited Shahdara

Chest Clinic on 11th July 2016 to discuss with staff of night

shelters regarding referral of TB suspects and to work as DOT

Providers for patients diagnosed among intimates of night

shelters.

31. TB Association of India has adopted Gaya district of Bihar to

make it TB Free. Dr. K.K Chopra, Director is member secretary

of the committee constituted for this purpose. First meeting of

the committee was held on 15th July 2016. Members discussed

the plan of project implementation in the meeting.

32. A CME was organized in Dr MC Joshi Hospital under R.K.

Mission Chest Clinic on 21st July’16.  Dr. K.K. Chopra, Directordelivered a lecture on “Standards of TB Care in India” during

the CME.

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33. Two days training of District TB Officers of Delhi state entitled

“Training of daily anti-TB treatment and 3IS (ICF, IPT, AIC)

strategy under TB HIV collaborative activities was held in New

Delhi TB Centre on 25th and 26th July 2016. Facilitators were

from NACO, State RNTCP Cell, WHO and Maulana Azad Medical

College.

34. Meeting of Ethical Committee of NDTB Centre was held on

27th July 2016. A project entitled “Feasibility and Acceptability

of Screening TB suspects in night shelters of Delhi” facilitated

by ICMR, Chennai and funded by Global Fund was discussed

for ethical clearance. The project has already been cleared by

National OR Committee. After detailed discussion the project

is cleared.

35. Meeting to discuss short term schedule for MDR TB cases was

held on 27th July 2016 in Central TB Division. Dr. K.K Chopra

(Director) and Dr. M. Hanif (Microbiologist) participated as

national experts. Issues of second line LPA, relaxation in norms

to introduce bedaquiline were also discussed.

36. Dr. K.K. Chopra, Director was panelist for live IMA webcast on

28th July 2016. Latest updates on TB management and

prevention were discussed.

37. Core group meetings of ECHO project was held on 4th August

2016 in NITRD. The purpose of meeting was to give orientation

of the project and its utility for RNTCP in Delhi. Dr. K.K. Chopra,

Director attended the meeting as Delhi State RTNCP

representative.

38. A meeting with nodal officers of DRTB centres and District TB

Officers was held in NITRD on 5th August 2016. Purpose was to

sensitize DTOs about ECHO Project, the modalities and timeline

for setting up hubs in DRTB Centres. Dr. K.K. Chopra, Director

attended the meeting.

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39. Delhi TB Association organised one day sensitization workshop

for community volunteers on 5th August 2016. Dr. K.K. Chopra,

Director delivered a lecture on Hazards of irregular treatment

and prevention of MDR TB.

40. Delhi state RNTCP review meeting was held on 10th August

2016 in New Delhi TB Centre. Dr. K.K. Chopra, Director, STDC

presented the analysis of quarterly reports of 25 chest clinics.

Principal Investigators of different OR projects being conducted

in Delhi state presented the update on the projects.

41. One day orientation programme for doctors of Malviya Nagar

Hospital was organised on 12th August 2016. Dr. M. Hanif,

Microbiologist and Dr. Zeeshan facilitated the programme.

Doctors were briefed about CBNAAT, its use and clinical

significance in diagnosis of TB and MDR TB.

42. Quarterly review of PMDT activities of Delhi state for 2nd quarter

2016 was held on 17th August 2016 in NDTB Centre. Nodal

officer of culture DST labs and DRTB centres presented their

activities for the quarter. Issues related to newly established

CBNAAT labs and nikshay entries were discussed and

appropriate decisions were taken.

43. On 20th August 2016, 31 students of final year students of

B.Sc (Hons) Nursing of Safdarjung College of Nursing were

sensitized about care of TB patients under RNTCP in detail i.e.

TB as a disease, treatment modalities etc. and also role of nurse

for care of TB patients.

44. A meeting to make preparation for setting up of gene sequences

and IGRA lab in NDTB Centre was held on 1st September 2016

in NDTB Centre. The meeting was attended by representatives

from WHO, Central TB Division and Delhi state RNTCP.

45. Training for clinicians and researchers in GCP (Good Clinical

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Practices) and Schedule Y to be followed for conducting clinical

and drug trials was held at NITRD on 2nd September 2016. Dr.

K.K. Chopra, Director attended the training.

46. Ethical committee meeting of NITRD was held on 2nd September

2016. Dr. K.K. Chopra, Director attended the meeting. Three

research protocols and two drug trial notifications were

discussed.

47. A sensitization programme for health workers of SOSVA NGO

was held in NDTB Centre on 7th September 2016. They were

briefed about symptoms of TB diagnosis, management and

prevention of TB. Twelve health workers attended the

sensitization programme.

48. WHO-RNTCP-IPC National collaborative workshop on Causality

Assessment for Pharmacovigilance of Anti-Tubercular Medicines

in India was conducted by Central TB Division with WHO on 8th

and 9th September 2016. Dr. K. K. Chopra, Director and Dr.

Shanker Matta, Epidemiologist attended the workshop.

49. Training of trainers for New Technical and Operative Guidelines

under RNTCP was held from 18th to 23rd September 2016 at NTI

Bangalore. Dr. K.K. Chopra, Director participated in the

training programme.

50. A meeting regarding research project “Comparison of pooled

sample examination versus single sample ability to detect drug

resistance ‘was held on 27th September 2016 in Paediatric

Department of Kalawati Hospital. Dr. K.K. Chopra, Director

and Dr. M. Hanif, Bacteriologist are co-investigators for the

study approved by National OR Committee. The revised

proposal of the study was discussed and prepared to be

submitted in Central TB Division for funding.

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51. Two days workshop was held by WHO and Ministry of Health &

Family Welfare in Delhi from 28th and 29th September 2016

regarding impact of air pollution on health. Dr. K. K. Chopra,

Director and Dr. Shanker Matta, Epidemiologist attended the

workshop.

52. A guest lecture on ‘Electronic Nicotine Delivery System (ENDS)

as a substitute to conventional cigarette: an evidence based

Audit was organised on 30th September 2016 in community

Medicine, Department of MAMC. Dr. K. K. Chopra, Director

and Dr. Shanker Matta, Epidemiologist attended the lecture.

Dr. K. K. Chopra, Director also chaired the scientific session.

53. A RNTCP sensitization programme was organised on 3rd

October, 2016 for first year B.Sc students of Holy Family

Nursing College. 56 students participated in the programme.

They were briefed about diagnosis and management of TB

under RNTCP and how to prevent TB in community. Dr.

Shanker Matta (Epidemiologist) and Mrs. Gurpreet Kaur (PHN)

were facilitators.

54. A meeting of national level expert committee for diagnosis and

treatment of TB was organised in Nirman Bhawan on 6th October

2016. Dr. K.K. Chopra, Director participated in the meeting as

one of the national experts. Shorter regimen for MDR TB and

new strategic plan 2017-2023 was discussed in the meeting.

55. Financial management workshop for District TB Officers and

District Accounts Managers under Delhi RNTCP was held on

7th October 2016, in STDC Delhi.

56. Ethical Committee meeting of World Lung Foundation – South

Asia was held on 8th October 2016. Dr. K.K Chopra, Director

attended the meeting as its member. Two research projects

related to tobacco cessation were discussed and approved.

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57. 67th TB seal campaign of NCT of Delhi was held in LG House on

14TH October 2016. Dr. K.K Chopra, Director attended the

campaign.

58. A CME on TB Notification was organised by The Union and

East Delhi Medical Association on 15th October 2016. Dr. K.K

Chopra, Director attended the CME and delivered a lecture on

“Standards of TB control in India”.

59. Two days consultative workshop on "National Strategic Plan for

TB Control in India (2017-23)" was held in New Delhi on 18th

and 19th October 2016. Dr. K.K Chopra, Director attended the

meeting as an expert and delivered a lecture on “Challenge of

RNTCP implementation – State perspective” during the

workshop.

60. A training programme for 27 students of (Lady Health Visitors)

from Lady Reading Health School was conducted on RNTCP-

TB on 2nd November 2016.

61. Hands on training of Project ECHO was conducted in New Delhi

from 8th to 10th November 2016. Dr. K.K. Chopra, Director

attended the training with representatives from DRTB Centres

of six sites of India and State TB Department. Training was

conducted by facilitators from New Maxico University.

62. A trial run of project ECHO was conducted at NITRD on 11th

November 2016. All DTOs of Delhi state attended the trial run.

They were sensitized about the project ECHO and weekly clinics

to be conducted.

63. One day workshop for “Stake holder for NABL accreditation of

selected 15 laboratories” was organised on 13th November 2016

in Pune. The workshop was organised by Central TB Division

and FIND. STOs and STDC Directors and Microbiologists of

selected 15 laboratories participated in the workshop. Steps

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for process of NABL accreditations were discussed and timeline

for activities was drawn. Dr. K.K. Chopra, Director and Dr. M.

Hanif, Microbiologist participated in the workshop.

64. Delhi State Operational Research Committee meeting was held

on 15th November 2016 in NDTB Centre. Faculty of the Centre

participated in the meeting. Dr. K.K. Chopra, Director

presented status of three OR projects being undertaken at

NDTB Centre. In all 22 OR proposals and thesis protocols

were presented and discussed.

65. Secretary Health (Government of NCT of Delhi) conducted a

review of various programmes of Delhi state on 21st November

2016. Dr. K.K. Chopra, Director presented the status of RNTCP

in Delhi state during the review meeting. Various activities of

RNTCP were discussed including challenge in financial

management.

66. A meeting of NSP sub group 3 (Treatment Gp) was held on 25th

November 2016 in NDTB Centre. Representatives from WHO,

Central TB Division and faculty of NDTB Centre participated in

finalising the draft of treatment as part of NSP strategy.

67. On the occasion of World AIDS DAY, a health mela was organised

in Jawaharlal Nehru Stadium on 1st December 2016. Central

TB Division put up a stall in the mela. NDTB Centre staff

participated and put up demonstration of rapid TB Diagnostic

– Gene expert test at the health mela TB stall.

68. State level review meeting for Bedaquiline implementation was

held in Delhi on 8th December 2016. Dr. K.K. Chopra, Director

coordinated the meeting. Nodal officers of DRTB sites presented

the status of cases put on Badequiline containing regimen.

Attached DST laboratories presented the data of the second

line DST conducted on MDR cases to decide about their

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eligibility for Bedaquiline. Representatives from Central TB

Division, WHO and The Union attended the review meet.

69. Review meeting of “SMS for Sure” project was held in NDTB

Centre on 9th December 2016. DOT Providers of selected chest

clinics participated in the review meet. The data of patients

enrolled in the project was discussed.

70. In MDR-ECHO clinic (which is held every Wednesday) on 14th

December 2016, Dr. K.K. Chopra, Director delivered a Dietetics

on “Challenges and constrains in Management of MDR TB”.

This was in form of video-conferencing with District TB Officers

of Delhi state.

71. Dr. Shanker Matta, Epidemiologist participated in three days

training programme on “Logistics Management” from 14th to

16th December 2016 held in NTI, Bangalore. This was conducted

by Central TB Division and emphasis was on systematically

managing the distribution CBNAAT cartridges in the

laboratories.

72. NATCON 2016 was held from 16th to 18th December 2016 at

PGI Chandigarh. Dr. K.K. Chopra, Director and Dr. M. Hanif,

Microbiologist attended the NATCON. Dr. Chopra delivered a

lecture on “Standards of TB Care in India” during CTD session

of Eradicating TB by 2050. Five research papers prepared by

NDTB Centre were selected for poster presentation during the

NATCON.

73. A CME programme was organised in the auditorium of Lady

Hardinge Medical College by Delhi State RNTCP team on 21st

December 2016. Dr. K.K. Chopra, Director delivered a lecture

on “Standards of TB Care in India” during the CME.

74. A meeting to finalise the strategy for conducting “Active Case

Finding – TB Services to door steps” was held in STDC on 23rd

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December 2016. Representatives from State TB Cell and WHO

participated in the meeting and discussed the strategies for

conducting the project in Delhi state.

75. A one day sensitization programme for active case finding

survey was conducted on STDC on 26th December 2016. District

TB Officers of all the districts attended the programme. Steps

of conducting and monitoring the survey were discussed. Their

feedback on smoothly conducting the survey was also taken

up and incorporated in the strategy.

76. ECHO MDR clinic was held on 4th January 2017. Didactic for

the clinic was on “Nationwide special TB campaign for Active

Case Finding” by Dr. K.K. Chopra, Director. This was followed

by clinical case discussion by DTO, Gulabi Bagh Chest Clinic.

77. A meeting to review the progress of Paediatric CBNAAT Project

was held on 6th January 2017 in STDC. Representatives of

State TB Office, FIND and Dr. M Hanif, Microbiologist, NDTB

Centre participated in the meeting. It was decided to wind up

the project by March 2017.

78. A meeting of Treatment Group (National Strategic Plan 2017-

2023) was held on 6th January 2017 in STDC. Representatives

from NDTB Centre, WHO and Central TB Division participated

and discussed to finalise the treatment group write up.

79. A national expert committee meeting was held on 18th January

2017 with DGHS, Ministry of Health & Family Welfare,

Government of India regarding expansion of Bedaquiline with

CAP conditions to other parts of the country. Dr. K.K. Chopra,

Director attended the meeting. It was decided to identify at

least 30 sites where facilities of second line DST are available

and bedaquiline can be introduced in pre-XDR and XDR cases

of these sites.

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80. Regarding nationwide Active Case Finding Campaign, a meeting

of District TB Officers of Delhi state with NGO partners was

held in STDC on 19th January 2017. Constitution of field teams,

their work instruction and schedule for supervision of this

activity was discussed and finalised.

81. Weekly MDR-ECHO Clinic was held on 25th January 2017. This

time the clinic was conducted from STDC for monitoring of

Active Case Finding Survey. All the DTOs, NITRD Delhi, NTI

Bangalore and STO of Tamilnadu were connected online. Field

visit experiences of State Supervisors and DTOs were shared.

Issues in the field activity were also discussed and resolved

during the session. Similar sessions were also conducted on

1st and 8th February 2017.

82. Delhi TB Association organised a Community Volunteers

Training Programme – “Health: a Social Movement” on 27th

January 2017. Dr. K.K. Chopra, Director delivered a lecture

on ‘Hazards of irregular treatment and prevention of MDR TB”.

About 70 volunteers attended the session.

83. A CME was organised on 27th January 2017 in Rohini for

members of Indian Association of Paediatricians (North Delhi

Branch). They were briefed about CBNAAT paediatric project

and guidelines of paediatric TB diagnosis and management.

Dr. K.K. Chopra, Director attended the CME and participated

in panel discussion.

84. Weekly ECHO clinic was conducted from STDC on 1st February

2017. 38 speakers and 140 persons attended the clinic.

Activities of Active Case Finding Campaign being conducted in

Delhi State was reviewed. State Supervisors shared their

experiences and discussed various issues faced in the field.

85. Weekly ECHO clinic on 8th February, 2017 was conducted from

STDC hub. This was last session for review of Active Case

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Finding activities in Delhi State. 33 speakers and 119

participants attended the session. Final results of the two weeks

activity were reviewed in the session and DTOs suggested some

innovation to be included in second phase to be conducted in

July, 2017.

86. Delhi State Task Force meeting was held on 10th February,

2017 in AIIMS. Faculty of NDTB Centre participated in the

meeting as its members. Dr. Chopra, Director delivered a

lecture on ‘Standards of TB care in India”.

87. A CME was organised in Jaipur Golden Hospital, Rohini, New

Delhi on 11th February, 2017. The Doctors of various hospital

attended the CME. Dr. K.K. Chopra, Director delivered a lecture

on Clinical aspects and TB and its standard management.

88. One day sensitization for members of NGO VIHAN working in

the community was held on 13th February, 2017. 25 members

attended the programme. They were briefed about daily Anti

TB treatment for PLHIV as per TB-HIV Co-ordination programme.

Similar sensitization programme was held on 14th February,

2017 in which 20 participants attended the session.

89. Dr. Hanif (Microbiologist) attended an International Symposium

on Genomis of Mycobacterium Tuberculosis which was held at

NIRT, Chennai from 17th February, 2017 to 18th February, 2017.

During the symposium, many eminent scientists from CDC,

Atlanta, USA, University of Cambridge, U.K. Medical Research

Centre, U.K. and Deptt, of Biotechnology, Government of India

gave talks about whole genone sequencing and its application

in TB and MDR TB diagnosis. Each session had power point

presentations and panel discussions by distinguished scientists.

90. A workshop to discuss modalities to conduct Active TB Case

finding in red light area of GB Road, New Delhi was held on

10th Feb, 2017 in NDTB Centre. Representatives from State TB

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Cell, Delhi State AIDS Control Society and VIHAN, NGO

attended the workshop. During the workshop, the work

instructions were finalised as how to conduct the active case

finding campaign. It was decided to start the campaign from

27th February, 2017 till World TB Day.

91. A CME for faculty and resident doctors of BJRM Hospital was

conducted on 23rd Feb, 2017. Dr. K.K.Chopra, Director

delivered a lecture on ‘Recent Initiatives in Diagnosis and

Management of TB under RNTCP’.

92. A sensitization meeting with stake holders for Active Case

Finding among commercial sex workers and their family

members was conducted on 23rd February, 2017 in STDC.

Representatives from Chest Clinics – Pili Kothi and Lok Nayak

Hospital, VIHAN NGO, outreach workers and Peer group

working in GB Road area attended the sensitization. Process

of Active case Finding campaign was briefed to them.

93. The two days consultative meetings to finalize National Strategic

Plan (2017-23) was held in Delhi on 28th February, 2017 and

1st March 2017 by Central TB Division and WHO. Dr.

K.K.Chopra, Director participated as a member of Treatment

Group. Representatives from CTD, WHO, NGO, Partners, Medical

Colleges, National Institutes and experts from various fields

attended the meeting.

94. Ethical Committee meeting of NITRD New Delhi was held on

2nd March 2017. Dr. K.K. Chopra, Director attended the meeting

as one of its member. During the meeting, total eight projects

were discussed and some changes were suggested for

incorporation.

95. A CME for doctors and staff of Urban Training Health Centre,

Najafgarh was conducted on 10th March 2017. About 80 doctors

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and para medical staff attended the CME. Dr. K.K. Chopra,

Director delivered a lecture on “Newer Diagnostics and Standards

of TB Care in India”.

96. Mid-term review of Active Case Finding Campaign was held on

14th March 2017 at New Delhi TB Centre. The representatives

from Delhi State RNTCP team, VIHAN NGO and DSAC society

attended the review meeting. Dr. K.K. Chopra, Director

presented the findings of the campaign till date. The issue

faced in the field activities and outcome of the campaign was

discussed.

97. Weekly MDR ECHO clinic was held on 15th March 2017 in NITRD.

Didactic was delivered for the clinic by Dr. M. Hanif,

Microbiologist on “ EQA issues under the National Programmein Delhi State”.

98. Delhi State PMDT review meeting was held on 16th March 2017

in STDC Delhi. Nodal officers of culture DST labs and DRTB

centres presented their reports of the quarter. Various issues

related to labs and especially bedaqualine intake were discussed.

99. A CME was organised by R.K. Mission Chest Clinic on 20th

March 2017 as a part of World TB Day celebration. During the

CME, Dr.K.K.Chopra, Director delivered a lecture on “Standards

of TB Care in India (STCI) & Newer Diagnostics”.

100. A CME was organised by RBIPMT Chest Clinic on 21st March

2017 as a part of World TB Day celebration. During the CME,

Dr.K.K.Chopra, Director delivered a lecture on “Standards of

TB Care in India (STCI)”.

101. A “World TB day symposium” was organised by AIIMS on 22nd

March 2017. During the symposium Dr. K.K. Chopra chaired

a session on “Challenges of TB control”.

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102. A CME on “Newer Initiatives in Revised National Tuberculosis

Control Program in India” was organised by Department of

Community Medicine, Maulana Azad Medical College in

association with State TB Cell, New Delhi on 23rd March 2017.During the CME, Dr.K.K.Chopra, Director delivered a lecture

on “Current perspectives in management of TB”.

103. A seminar on TB was organised by All India Institute of Medical

Sciences (Clinical Microbiology Department) on 24th March

2017. During the CME, Dr.K.K.Chopra, Director chaired a

session on “TB control activities at national level”.

104. Delhi TB Association has organised Seminar on ”TB Controland Prevention with special reference to participation of Delhi

University (DU) Students to End TB” as part of this year WorldTB Day Celebrations on 30 th March 2017. During theprogramme, Dr. K.K. Chopra delivered a lecture “Challenges of

TB control”.

105. A press conference was organised in Press Club of India on 31st

March 2017. This was regarding dissemination of results of

Active Case Finding among female sex workers in GB Road

area. Dr. K.K. Chopra, Director briefed about the results of

Active Case Finding Campaign.

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1. The Annual General Meeting of TB Association of India was held

on 4th April 2016. Various staff members attended the said

meeting.

2. The Central Committee Meeting of TB Association of India was

held on 4th April 2016. Dr. K.K. Chopra, Director attended the

said meeting as its member.

3. A meeting to prepare Bye-Laws of NDTB Centre was held on 3rd

May 2016 in NITRD Delhi under chairmanship of Dr. Rohit Sarin

(Director-NITRD). Dr. Devesh Gupta (Addl. DDG-TB), Mr. Ahluwalia

(Secretary General-TAI) and Director, NDTB Centre were members

of the Committee. The draft Bye-Laws and Recruitment Rules of

Group B and C posts were discussed. It was decided to make

some minor corrections and circulate among its members for

approval and to be put up to the Chairman, Managing Committee,

NDTB Centre.

4. Final meeting of Bye-Laws Committee of New Delhi TB Centre

was held on 4th June, 2016 in NITRD. It was decided to put up the

final draft to Managing Committee of NDTB Centre.

5. Meeting of Managing Committee of New Delhi TB Centre was held

on 18th October 2016 in conference room of NDTB Centre under

the chairmanship of Dr. L.S. Chauhan. Various issues related to

general administration were discussed. The annual report and

budget estimates were approved.

6. A programme to distribute two wheelers to supervisory staff of

RNTCP was organised on 21st November 2016 by Delhi state RNTCP

department. The Health Minister of Government of NCT of Delhi

was the Chief Guest. Dr. K.K. Chopra, Director presented the

brief on activities of RNTCP in Delhi state during the function.

7. A meeting of Delhi TB Association was held on 25th January 2017

to discuss the issues regarding maintenance of their building.

Dr. K.K. Chopra, Director participated as one of its member.

8. Central Committee meeting of TB Association of India was held

on 27th March 2017. Dr.K.K.Chopra, Director attended the meeting

as its member. Staff members of NDTB Centre also attended the

Annual General Meeting of TAI on the same day.

MEETINGS

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CLINICAL SECTION

OPD Services

The Centre caters to patients of TB and Respiratory diseases referred

for diagnosis and opinion from different departments of LN Hospital,

GB Pant Hospital and Guru Nanak Eye Centre. Many private

practitioners and doctors of various hospitals of Delhi and neighbouring

states also refer patients for expert opinion on diagnosis and treatment.

Apart from seeing patients from our designated area, we are increasingly

getting many complicated cases from all over Delhi and outside Delhi.

Most of these patients have been under management from a variety of

doctors (both private and public sector) for months together and are

still searching for a valuable opinion. During the year, 2016-17 the

total OPD attendance at the Centre was 10157 and revisits were 9895.

The total attendance in the clinic was 20052. The table shows month-

wise distribution of OPD attendance

Total OPD Attendance during the year (April 2016 to March 2017)

S.No. Month Male Female Total

1. April’16 655 811 1466

2. May’16 767 914 1681

3. June’16 854 1197 2051

4. July’16 714 974 1688

5. August’16 697 1062 1759

6. September’16 700 920 1620

7. October’16 625 864 1489

8. November’16 610 858 1468

9. December’16 616 921 1537

10. January,17 665 1068 1733

11. February’17 623 1153 1776

12. March’17 686 1098 1784

Total 8212 11840 20052

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TB and Diabetic screening

As a routine all registered patients are tested for Blood Sugar (Fasting)

to detect Diabetes Mellitus before starting treatment. In all a total of

66 patients were put on DOTS during the year 2016-2017. Four

patients were found diabetic, they were referred to Diabetes clinic for

its management.

COAD Clinic

Other than TB patients, a bulk of our OPD attendance comprises of

COAD patients. As a standard protocol, we have a very well checked

out plan of management for them wherein their disease is well

controlled requiring no admissions/emergency room visits for acute

exacerbations. During the year, 562 patients were screened out of

which 310 were male and rest 252 were female which shows that

satisfaction level and acceptance to treatment of these COAD patients

is very high.

Tobacco and cessation clinic

Since January 2013, the tobacco cessation clinic is being run by our

staff where patients are made to understand the harmful effects of

smoking. Not only that, counseling sessions are being arranged for

them and we try to motivate them for leaving these habits. By the

end of March, 2017, 104 patients have been registered and then are

attending the clinic regularly. 43 of them have completely given up

smoking and are feeling better and healthy, 35 have reduced and

their habit of smoking and alcohol.

Radiological Examination

Table below gives month-wise distribution of radiological examination

done.

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X-ray examinations done during the year

(April 2016 to March 2017)

S.No. Month No. of New Cases Old Cases

X-ray done

1. April’16 102 85 17

2. May’16 145 122 23

3. June’16 106 82 24

4. July’16 132 110 22

5. August’16 155 119 36

6. September’16 122 99 23

7. October’16 111 83 28

8. November’16 131 102 29

9. December’16 105 80 25

10. January,17 117 84 33

11. February’17 133 99 34

12. March’17 202 158 44

Total 1561 1223 338

DOTS Centre

One DOT cum Microcopy Centre is situated in the complex of the

Centre. Here free diagnosis and treatment is provided to patients

who belong to the area according to RNTCP guidelines. The doctors

of the Centre screen the TB suspects, advise investigations and

categorize the patients suffering from TB for treatment. Patients of

the DOT centre also visit our OPD for management of side effects due

to intake of Anti-TB drugs.

Presently 28 patients are enrolled at DOTS Centre situated at NDTB

Centre and are taking regular treatment. The details are given below:-

Category No. of Patient

Cat I 22

Cat II 3

Pediatric cases 3

Total 28

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EPIDEMILOGICAL SECTION

Epidemiology section of New Delhi Tuberculosis Centre is involved in

various activities. Some of the key activities being undertaken are

screening of staff from various organizations, like National Zoological

Park, hotels, embassies, involvement in various projects, monitoring

and supervision of various chest clinics of Delhi, involvement in TB

related projects etc.

(A) Active Case Finding Campaign among high risk groups

One of the activity undertaken by the Epidemiology Department of

New Delhi Tuberculosis Centre was the supervision of Active case

finding campaign of TB cases in January 2017. Active case finding

campaign through house to house survey for search of TB symptomatic

was proposed by Central TB Division in January 2017. This was a

national level activity which is being implemented throughout the

country. This was a 2 weeks activity which is to be conducted thrice

in this year. A team of 4 persons which includes RNTCP DOT provider,

ASHA worker and NGO representative conducted house to house

survey. With the guidance of DTO, the team was to identify high risk

groups (slum population, prisons, construction sites etc), to look for

TB symptomatic. Before the survey all DTOs of Delhi state were trained

for this activity. They were also requested to do mapping of their

respective area specifically targeting slum population, construction

sites, prisons, and night shelters for this activity. A format was designed

for this survey. The team visiting the high risk groups had to note

details like name of the resident, age, sex address. A question

regarding symptoms of TB was asked, if the answer was no; the team

had to mark the house with chalk and move on to the next house. If

the answer was yes (that is any person in the family had cough for 2

or more weeks duration/fever etc) an on the spot sputum sample was

collected by the team and the patient is convinced to come to the

centre to provide second sputum sample. Mobile numbers of

symptomatic patients are noted so that they can be followed up later.

Supervision of this activity was conducted by staff of State TB cell,

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WHO consultant and NDTB faculty. At the end of the day the staff

had to submit the filled formats. Another important activity was the

entry of the identified TB cases on the Nikshay portal which has to

be entered by the data entry operator of the respective chest clinics.

For the ground level staff conducting house to house survey this was

an incentivized activity. For each positive case found and initiated on

treatment the government has proposed an incentive amount of Rs

500/- for the team involved in the survey.

During the ECHO based meet, various problems were highlighted by

DTO’s as well as the ground level staff, which were encountered during

the campaign. Problems like refusal to provide second sputum sample,

difficult areas to be covered, pockets with drug addicts/dangerous

areas etc were encountered as well as highlighted .Reason behind

highlighting these problems was to be prepared for the next ACF

activity which is to be conducted in the month of July and December

2017. During these months, campaign activity would be conducted

on similar lines taking into consideration the problems encountered

in the present survey

Results of the activity:

· Total number of persons screened : 189633

· Number of sputum suspects from whom : 2817

samples examined

· Number of TB patients diagnosed : 242

(B) ACF activity for TB cases in GB road area

Another activity undertaken by Epidemiology department, New Delhi

Tuberculosis Centre was Active case finding campaign through house

to house survey for search of TB symptomatic. This was a national

level activity which is being implemented throughout the country.

This was a 2 weeks activity which is to be conducted thrice in this

year. It was proposed that this activity should also be conducted in

the GB road area, which is also a red light area. An NGO by the name

of VIHAAN working in the field of HIV AIDS was involved. Outreach

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workers working with the AIDS programme were trained to identify

TB cases through house to house survey. Ground level staff from Pili

kothi chest clinic and LNJP chest clinic also attended the training.

Idea behind this was to help the team initiate patients treatment.

Staff from VIHAAN as well as outreach workers including peers

working in GB road area were trained to identify chest symptomatic

.This was a one day training programme conducted on 23rd February

2017. 4 teams were identified to conduct the survey. Each team

comprised of a Peer, Vihaan NGO representative and 2 outreach

workers. If a patient is found with TB symptoms the outreach worker

would note details of the patient and his sputum would be examined

at NDTB. The team has to ensure that sputum sample is collected

and they bring the patient to NDTB for x-ray as well as second sample.

An incentive of Rs 50 per sample is being given to the outreach worker

for bringing the patient. EP samples are being sent to LNJP for culture.

This was a 20 day long activity. Data compilation, analysis, monitoring

and supervision was undertaken by staff of NDTB

Results of the activity:

Total population screened : 2517

Total number of buildings covered : 22

Total number of rooms covered : 95

Total number of sex worker population screened : 1875

· Number of sputum suspects examined : 57

· Number of TB patients diagnosed : 02

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PUBLIC HEALTH SECTION

Public Health Section is one of the department of New Delhi

Tuberculosis Centre. This department is involved in various activities

including public health interventions. Following activities are

undertaken with the help of specialized staff which includes an

Epidemiologist, Public Health Nurse, Medical Social Worker and Multi

Purpose Health Worker:

Health talk

Health talk is one of the major activity through which information is

disseminated amongst masses. This is the simplest method to

communicate any message from one person to another. New Delhi

TB Centre is conducting in-house health talk on daily basis in its

main OPD hall where around 150-200 patients and their relatives

visit every day.

TB and film shows

By using audio-visual aids we try to generate awareness amongst our

patients and their relatives. We have various documentaries made

on TB which are being displayed every day in our main OPD hall. We

distribute print material to our visitors to recapture our message given

by us through word of mouth.

TB Supervisor course

During this year 4 batches took 3 months training of TB Supervisor

Course. The total strength of students was 51. Broadly our focus

was on following aspects:

· Tuberculosis

· RNTCP

· Modules used in RNTCP

· General aspects of health care

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Mantoux test

Mantoux test is done at the NDTB Centre. Apart from being referred

from the OPD of NDTB Centre the patients are also referred from

various government hospitals as well as those taking treatment by

private practitioners for Mantoux Screening.

During the period April 2016 to March 2017, 8425 mantoux test

were done at the NDTB Centre. Out of these, results of 7451 patients

were available. Month-wise Mantoux screening undertaken is as

follows:

Month Total test Test read Reactors Non Reactors

(2016-17) (>10mm) (<10mm)

April’16 619 549 279 270

May’16 719 634 281 353

June’16 895 787 400 387

July’16 741 649 312 337

August’16 723 635 325 310

September’16 657 590 242 348

October’16 667 580 237 343

November’16 597 509 215 294

December’16 639 572 236 336

January,17 753 659 271 388

February’17 767 691 291 400

March’17 648 596 263 333

Total 8425 7451 3352 4099

Anti TB week celebration

To mark the occasion i.e. World TB Day (24th March) we organise

different community based programmes with various NGOs working

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with us. This year also, our organisation conducted different

programmes as per below mentioned schedule

Date & Time Programme Methodology Participants

2.4.2017

10.00 AM Inauguration All Participants Bacho Ka Ghar

of Anti TB to write poem SPYM (Male)

Week Poem on TB SPYM (Female)

Competition + Student TB

Supervisory

3.4.2017 Painting Painting Bacho Ka Ghar

10.00 AM Competition competition SPYM (Male)

covering various SPYM (Female)

aspects of

Tuberculosis

4.4.2017 Slogan and All participants Bacho Ka Ghar

10.00 AM completion will write slogan SPYM (Male)

speech and present SPYM (Female)

speech on TB

7.4.2017 Quiz All participants Bacho Ka Ghar

10.00 AM competition to NGO + TB SPYM (Male)

Supervisor SPYM (Female)

students to + Student TB

answer questions Supervisory

regarding

Tuberculosis

24.4.2017 Function Prize Bacho Ka Ghar

11.00 AM distribution SPYM (Male)

SPYM (Female)

+ Student TB

Supervisory

All the winners of competition were awarded prizes. This year theme

is “Unite to End TB”. This event is covered by local news paper named

‘SAHAFAT’ Delhi.

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Community meeting and health talk

31st May ‘World No Tobacco day’ was celebrated All visitors

2016 where a health talk was delivered of OPD

highlighting the harmful effects of

smoking and other drugs.

5th June World Environment Day was celebrated Staff

2016 at our Centre. The staff was requested NDTBC

to voluntarily donate a plant for centre.

1st July An interaction session was organized by Doctors

2016 the Centre where all the doctors and other and other

staff attended the session. The new drug staff

regimen and treatment updates were

explained to staff by our doctors on

‘DoctorsDay’.

11th July A community meeting was organized at All

2016 Mata Sundari Road Juggi Cluster. The residents

local community was sensitized about TB

and its importance.

12th A quiz competition was organized for TBHV Students

August students on youth rights to generate TBHV &

2016 awareness about youth programmes. staff

20th 76th Annual day was celebrated on All staff

November 20th November 2016 where CMEs for

2016 doctors was organized. The staff was

invited for lunch. Various sports

competitions were organized by the

Centre to mark the occasion.

1st A health talk was organized at Staff and

December SPYM girls where inmates and staff inmates of

2016 were sensitized about AIDS and HIV. SPYM

female

24th March Anti TB Week, World TB Day Celebration

2017

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TB Screening:

NDTB Centre is not only catering to TB patients but also tries to

reach community through its community based programmes. There

are three organizations namely, SPYM Girls (Street and Working

Children), SPYM Boys and Bachon Ka Ghar Orphanage working in

old Delhi area. All children of these organizations were screened for

TB. This year 103 children were examined.

During the month of February / March 2017, Active case detection

activity was conducted in collaboration with VIHAN. VIHAN is an

organisation working for HIV positive patients. They try to detect the

positive cases from different brothel houses. Recently with the help

of outreach workers we have screened 56 TB suspects, out of which 3

were put on treatment. They are taking medicines from Pili Kothi

Chest Clinic.

S. Gender X-ray Sputum CBNAAT Put on

No. examination examination treatment

-ve +ve -ve +ve - -

1. Male 16 - 14 - - -

2. Female 35 5 33 1 5 3

51 5 47 1 5 3

5 patients underwent CBNAAT after X-ray examination.

In the month of March 2017, we have adopted three communities

with the objective of making them TB free community. Aim was to

find TB symptomatic in the community and if diagnosed with TB, to

initiate treatment. The communities adopted and made TB free are:

· 100 quarter behind Ferozshah Kotla Stadium

· Kotla Road Juggi Cluster near Bal Bhawan

· Juggi Cluster, Mata Sundari Road

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The results of TB screening activity conducted in these areas are

given below in the table:-

Results of TB screening activity

S. Name of the Total Total Number of Put on

No. community house population symptomatic treatment

average found

population

/house

1. *100 quarter 171 855 5 1

2. **Kotla Road 125 250 13 1

Juggi

3. ***Mata 190 950 13 -

Sundari Road

Total 486 2055 31 2

* 100 quarters consists of 171 houses out of which 147 houses

were covered by our health workers, 24 houses were locked. Only

five symptomatic were found who were further screened at our Centre.

1 patient was diagnosed with TB and he was put on treatment from

our DOT Centre under Cat I sputum negative regime.

** In Kotla Road Jhuggi, there are total 125 jhuggies out of which

25 jhuggies are in duplicate means one person having two jhuggies

and rest of 50% i.e. 50 juggies found were locked. Only 50 jhuggies

were covered and the population covered was 250. 13 symptomatic

were screened. Out of which 1 was diagnosed with TB and put on

treatment.

*** The third community adopted is Mata Sundari Road, Jhuggi

Cluster, New Delhi. Where approximately 300 plus jhuggis were

found and 190 jhuggis were surveyed by our health worker. People

residing there are engaged in different factories of car spare parts

situated in the community itself. Most of them are illiterate and

alcoholic. In all 13 symptomatics were found.

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MYCOBACTERIAL LABORATORY

The laboratory is certified as Intermediate Reference Laboratory by

Central TB Division, Min. of Health & Family Welfare, Government of

India for Line Probe Assay, solid and liquid culture and DST. Samples

are received from 17 chest clinics of Delhi for diagnosis and follow-

up under PMDT activities. Base line drug susceptibility testing for

second line drugs are being carried out in routine using MGIT 96

liquid culture system. This laboratory is being selected as one of the

site to conduct Line Probe Assay for second line drugs.

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Annual Annexure M for the year, 2016 (District Wise)

Name of Nos. of Nos. of Nos. of TB Nos. of Nos. of Nos. of Total Total Total

DMC TB TB suspects TB suspects follow-up follow-up nos. of nos. of nos. of

suspects suspects undergoing found to patients patients slides negative positive

examined found repeat be positive examined found examined slides slides

for to be diagnostic on repeat to be examined examined

diagnosis positive examination diagnostic positive

examination

BJRM 6649 679 86 5 1938 68 15355 1411 13944

GTBH 10505 1338 55 4 2173 193 23299 2849 20450

HEDGEWAR 4566 610 43 5 826 82 10027 1322 8705

KCC 6514 771 18 2 2909 141 15966 2526 13440

LNH 9676 796 30 1 818 67 18458 1647 16811

JHANDEWALAN 2520 425 18 2 1277 111 6307 950 5357

SPM MARG 4463 503 26 3 1014 72 9925 1139 8786

SHAHDARA 5303 782 244 2 2057 206 12647 1724 10923

PATPARGANJ 13999 1954 317 3 4556 286 33019 4088 28931

RKM 2673 303 146 24 764 44 6370 645 5725

NEHRU NAGAR 13019 1708 65 13 6170 508 35143 4148 30995

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MOTI NAGAR 11491 1601 197 29 3659 181 25971 3132 22839

RTRM 8948 934 58 7 2134 212 20158 2053 18105

NARELA 6936 1034 16 0 2518 235 16450 2235 14215

K. NAGAR 6472 1067 19 3 3397 296 16258 2387 13871

NDMC 21837 2469 41 1 3127 231 46688 5227 41461

BSA 6947 951 116 3 2341 157 16470 1937 14533

DDUH 10805 1379 129 21 3622 246 25193 2980 22213

GULABI BAGH 3571 292 89 3 694 52 7698 591 7107

LRS 7710 850 30 1 2151 137 17602 2390 15212

SGMH 8016 1091 25 1 2855 108 18686 2142 16544

SHASTRI PARK 6955 1068 90 11 2841 268 16908 2368 14540

DESHRAJ 6109 759 70 14 1857 170 12374 1694 10680

MALVIYA NAGAR 5137 841 8 2 2976 421 13217 2096 11121

BIJWASAN 5363 532 38 18 2622 279 14320 1452 12868

Total 196184 24737 1974 178 61296 4771 454509 55133 399376

During the year, a total of 1,96,184 TB suspects were examined for diagnosis in all 25 chest clinics

of Delhi state out of which 24,737 were found positive. 4,54,509 slides were examined as per data

received from TB laboratory abstract. Out of these 55,133 slides were found positive. A total of

3,99,376 slides were found negative.

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On-site Evaluation visit and Panel Testing

An IRL team comprising of Microbiologist, one Medical officer and

one Laboratory Technician visits each chest clinic at least once a year

to DTCs for on-site evaluation. During the visit, randomly selected

DMCs are also covered for evaluation.

Recommendations of the annual supervisory visits to the districts by

the IRL have focused on operational and technical problems of the

laboratories including availability of staff, infrastructure, regular

supply of consumables and training. During the visit, panel testing

for STLs was conducted. DMCs reporting false positive or negative

errors in RBRC were also visited by the IRL team.

List of DTCs visited by IRL Team for OSE

S. No. Name of Chest Clinic Date of visit

1 BJ RM Chest Clinic 03/03/2016

2 Patparganj Chest Clinic 09/03/2016

3 GTB Chest Clinic 15/02/2016

4 R.K. Mission Chest Clinic 11/04/2016

5 CH. Desraj chest clinic 30/05/2016

6 S.Park Chest Clinic 13/07/2016

7 KCC Chest Clinic 14/07/2016

8 BSA Chest Clinic 27/07/2016

9 Narela Chest Clinic 26/07/2016

10 Karawal Nagar Chest clinic 29/07/2016

11 LNH Chest Clinic 04/08/2016

12 SGMH Chest Clinic 09/08/2016

13 SPM Chest Clinic 11/08/2016

14 Gulabi Bagh Chest Clinic 16/08/2016

15 Shahdara Chest Clinic 19/08/2016

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PMDT activities carried out during the year April 2016 – March 2017

(Specimens processed on culture or DST)

Quarter Diagnostic Follow-up LPA DST H+R H+R Only Only

2016- Sputum Specimens Done Sens Res H R

2017 Specimens inoculated Res Res

inoculated

2Qr 2016 1848 1745 1350 1030 143 122 22

3Qr 2016 1747 1759 1318 1023 168 115 22

4Qr 2016 1359 1693 1354 1078 145 78 23

1Qr 2017 1597 1867 1044 847 111 73 13

TOTAL 6551 7064 5066 3978 567 388 80

The table provide the details of laboratory tests done under PMDT

activities during the year 2016-17. A total of 6551 sputum specimens

were processed out of which 567 cases turned out to be MDR-TB and

80 Rif mono resistant.

16 Jhandewalan Chest Clinic 07/09/2016

17 Malviya Nagar Chest Clinic 20/09/2016

18 Bijwasan Chest Clinic 14/09/2016

19 NITRD Chest Clinic 22/12/2016

20 RTRM Chest Clinic 27/12/2016

21 Hedgewar Chest Clinic 07/11/2016

Programmatic Management of Drug Resistant Tuberculosis (PMDT)

Activities

The laboratory got certification by CTD for Line Probe Assay, solid

and liquid culture and DST. Currently sputum samples received from

17 chest clinics for diagnosis and follow-up under PMDT activities in

Delhi.

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Laboratory examinations carried out for cases referred by

Private Practitioners during the year 2016 - 2017

Month Laboratory examinations

Smear Culture Drug

examination (Solid) Susceptibility

testing by

solid culture

April 242 242 28

May 251 251 34

June 323 323 20

July 257 257 22

August 202 202 20

September 180 180 00

October 149 149 12

November 112 112 20

December 124 124 13

January 116 116 16

February 160 160 12

March 137 137 18

TOTAL 2253 2253 215

Table depicts data of month wise laboratory examinations carried out

during the year 2016-17. A total of 2253 smears were examined,

equal number of cultures were done and 215 drug susceptibility

testing were performed.

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TRAINING AND MONITORING SECTION

The institute is actively involved in the training of various

medical and paramedical personnel who visit from Delhi and other

states of our country, in implementation of strategies under Revised

National Tuberculosis Control Programme (RNTCP). Several training

programmes have already been conducted by the institute for doctors,

Medical Students from Mulana Azad Medical College & Patel Chest

and paramedical personnel (Dot Provider, STS, DEO, Lab Tech., Sr.

Lab Tech., Treatment organizers and Sr. Treatment supervisors).

Training is also imparted to the nursing students from Ahilaya Bai

College of Nursing, Lady Reading Health School, Safdurjung Hospital,

Rajkumari Amrit Kaur College of Nursing. The trainings done during

the year are given as under:

TRAINING ACTIVITIES

In all during the year, 115 days of training sessions were conducted

wherein 2439 personnel were trained regarding various aspects of

the RNTCP which includes 90 sessions. Topics like infection control

for health workers, roles and responsibilities of nursing personnel

for care of TB patients and prevention against tuberculosis were also

discussed in detail. The details of training are given below:

Training Programmes conducted from 01st April 16 to 31st March 17

Details of Trainings/ Sensitizations held at New Delhi TB Centre (STDC)

01st April 2016 to 31st March 2017

S. Detail of Training Period Days No. of

No. Participants

1 Workshop to discuss the 07.04.2016 07.04.2016 1 11

modalities to roll out the

Bedaquiline conditional &

expanded access programme

2 RNTCP sensitization of 11.04.2016 11.04.2016 1 15

Nursing Students from

RAKCON School of Nursing

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3 Sensitization programme for 18.04.2016 18.04.2016 1 68

medical Students of Mulana

Azad Medical college under

RNTCP

4 Workshop for DTO’s for 25.04.2016 25.04.2016 1 11

CBNAAT labs on quarterly

performance for CBNAAT

monitoring indicators

5 Sensitization programme for 26.04.2016 26.04.2016 1 22

DOT Providers under RNTCP

and review for project “SMS

for sure”

6 Sensitization programme for 27.04.2016 27.04.2016 1 18

Lab. Technicians under

RNTCP and performance for

CBNAAT monitoring

indicators under RNTCP

(Batch-I)

7 Sensitization programme for 28.04.2016 28.04.2016 1 21

Lab. Technicians under

RNTCP and performance for

CBNAAT monitoring

indicators under RNTCP

(Batch-II)

8 Training programme for 29.04.2016 29.04.2016 1 37

DTO’s on guidelines for

involvement of private

practitioners and partnership

programme under RNTCP

9 Continuing Medical 07.05.2016 07.05.2016 1 27

Education (CME) programme

under notification project

for private practitioners for

Narela District

10 Workshop cum review meet 11.05.2016 11.05.2016 1 31

on various projects with

DTO’s and medical officers

for Delhi State.

11 Sensitization programme for 12.05.2016 12.05.2016 1 32

medical Students of Mulana

Azad Medical college under

RNTCP

12 Delhi State workshop cum 18.05.2016 18.052016 1 36

review meet on TB/HIV

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co-ordinators with DTOs and

medical officers.

13 Sensitization programme for 19.05.2016 19.05.2016 1 7

Night shelter care takers of

Narela District

14 Delhi State sensitization 20.05.2016 20.05.2016 1 8

programme for Night shelter

care takers for District

Gulabi Bagh

15 Sensitization programme for 20.05.2016 20.05.2016 1 5

Night shelter care takers of

District SPM Hospital

Shastri Park

16 Skill training programme for 23.05.2016 27.05.2016 5 16

DRTB Counsellors on TB

control under RNTCP

17 Continuing Medical 24.05.2016 24.05.2016 1 21

Education (CME) programme

under notification project for

private practitioners of

District Jhandewalan

18 Continuing medical 26.05.2016 26.05.2016 1 14

education (CME) programme

under notification project

for private practitioners of

District SPMarg Pilli Kothi

19 Sensitization programme 26.05.2016 26.05.2016 1 12

for Night shelter care takers

of District Sanjay Gandhi

20 Sensitization programme for 27.05.2016 27.05.2016 1 10

Night shelter care takers of

Jhandewalan District under

RNTCP

21 sensitization programme for 27.05.2016 27.05.2016 1 13

Night shelter care takers for

Shastri Park District under

RNTCP

22 Continuing medical 31.05.2016 31.05.2016 1 20

education (CME) programme

under notification project

for medical officers for

District -JPC Hospital &

Chest Clinic

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23 RNTCP sensitization for 01.06.2016 01.06.2016 1 15

Nursing Students of

Safdarjung college for Nursing

24 Sensitization programme 02.06.2016 02.06.2016 1 8

for Night shelter care takers

of District Karawal Nagar

25 Sensitization programme 03.06.2016 03.06.2016 1 10

for Night shelter care takers

of District Kingsway Camp

Hospital

26 Delhi State sensitization 03.06.2016 03.06.2016 1 9

programme for Night

shelter care takers of

District NDMC Poly Clinic

27 Sensitization programme 09.06.2016 09.06.2016 1 12

for Night shelter care takers

of District DDU Hospital

28 Delhi State sensitization 10.06.2016 10.06.2016 1 10

programme of Night shelter

care takers of District

Lok Nayak

29 Sensitization programme for 10.06.2016 10.06.2016 1 14

Night shelter care takers of

District Nehru Nagar

30 Continuing Medical 13.06.2016 13.06.2016 1 9

Education (CME) programme

under notification project

for medical officers of SBS

Marg District NDMC

Poly Clinic

31 Sensitization programme for 14.06.2016 14.06.2016 1 68

medical students of Mulana

Azad Medical college under

RNTCP

32 Sensitization programme for 17.06.2016 17.06.2016 1 14

Night shelter care takers of

District Moti Nagar

33 Sensitization programme for 17.06.2016 17.06.2016 1 7

Night shelter care takers of

District NITRD

34 Sensitization programme for 18.06.2016 18.06.2016 1 5

Night shelter care takers of

District BSA Hospital

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35 Sensitization programme for 24.06.2016 24.06.2016 1 8

Night shelter care takers of

District Patparganj

36 Sensitization programme for 24.06.2016 24.06.2016 1 12

Night shelter care takers of

District GTB

37 Sensitization programme for 25.06.2016 25.06.2016 1 10

Night shelter care takers for

District Ch. Des Raj Hospital

38 Continuing Medical 28.06.2016 28.06.2016 1 22

Education (CME) programme

under notification project of

medical officers

39 Sensitization programme for 29.06.2016 29.06.2016 1 25

Night shelter care takers of

District BJRM Hospital

40 Sensitization programme for 30.06.2016 30.06.2016 1 8

Night shelter care takers of

District Shahdara

41 Workshop on Delhi PMDT 01.07.2016 01.07.2016 1 9

scale up plan meeting under

the RNTCP

42 Sensitization programme for 11.07.2016 11.07.2016 1 20

medical Students of Mulana

Azad Medical college under

RNTCP

43 Training programme for 25.07.2016 26.07.2016 2 31

District TB officers on daily

Anti Tuberculosis treatment

and 3 I’s strategy under TB-

HIV collaboration activities

44 Training programme for 04.08.2016 05.08.2016 2 22

Medical officers on daily Anti

Tuberculosis treatment and

3 I’s strategy under TB-HIV

collaboration activities

45 Training programme for 08.08.2016 09.08.16 2 25

Medical officers on daily

Anti Tuberculosis treatment

and 3 I’s strategy under

TB-HIV collaboration

activities

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46 Sensitization programme 10.08.2016 10.08.2016 1 24

for project SMS for sure,

Case Notification programme

along with RNTCP review

meeting

47 Sensitization programme for 16.08.2016 16.08.2016 1 68

medical Students of Mulana

Azad Medical college under

RNTCP  

48 Sensitization programme 17.08.2016 17.08.2016 1 34

regarding performance of

PMDT and review under

RNTCP

49 RNTCP sensitization of 20.08.2016 20.08.2016 1 31

Nursing Students of Bsc (H)

4th year student from School

of Nursing

50 Training programme for STS 22.08.2016 22.08.2016 1 18

on daily Anti Tuberculosis

treatment and 3 I’s strategy

under RNTCP/NACO

programme

51 Training programme for STS 23.08.2016 23.08.2016 1 17

on daily Anti Tuberculosis

treatment and 3 I’s strategy

under TB-HIV collaboration

activities

52 Training programme for 26.08.2016 26.08.2016 1 16

TBHVs for Anti Tuberculosis

treatment on daily regimen

under RNTCP

53 Training programme for 29.08.2016 29.08.2016 1 25

Dots Plus TB HIV supervisors

on daily Anti Tuberculosis

treatment and 3 I’s strategy

under TB-HIV collaboration

activities

54 Training programme for Dots 30.08.2016 30.08.2016 1 20

Plus/STLS on daily Anti

Tuberculosis treatment and

3 I’s strategy under TB-HIV

collaboration activities

55 Training programme for 31.08.2016 31.08.2016 1 17

STLS on daily Anti

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Tuberculosis treatment and

3 I’s strategy under TB-HIV

collaboration activities

56 Sensitization for SOSVA 07.09.2016 07.09.2016 1 11

Non government organisation

staff under RNTCP

57 Sensitization programme for 12.09.2016 12.09.2016 1 18

medical students of Mulana

Azad Medical college under

RNTCP

58 RNTCP sensitization for 03.10.2016 03.10.2016 1 26

Nursing Students for Bsc (H)

1st year students from Holy

Family School for Nursing

59 RNTCP sensitization for 03.10.2016 03.10.2016 1 28

Nursing Students for Bsc (H)

1st year student from Holy

Family School of Nursing

60 Workshop cum training on 07.10.2016 07.10.2016 1 33

financial management

(account) under RNTCP

programme

61 Sensitization programme for 10.10.2016 10.10.2016 1 70

medical students of Mulana

Azad Medical college under

RNTCP

62 Meeting on State operational 15.11.2016 15.11.2016 1 19

Research committee activities

under RNTCP programme.

63 Sensitization programme for 17.11.2016 17.11.2016 1 20

medical students of Mulana

Azad Medical college under

RNTCP

64 RNTCP sensitization for 07.12.2016 07.12.2016 1 24

Nursing students for Bsc (H)

2nd year student from

Safdarjang Hospital

New Delhi

65 RNTCP sensitization for 07.12.2016 07.12.2016 1 23

Nursing Students for Bsc (H)

2nd year student from

Safdarjang Hospital

New Delhi

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66 Sensitization programme on 09.12.2016 09.12.2016 1 15

SMS sure programme under

RNTCP

67 Sensitization programme for 12.12.2016 12.12.2016 1 18

medical Students of Mulana

Azad Medical college under

RNTCP

68 Delhi state meeting cum 26.12.2016 26.12.2016 1 27

elaborate Active case finding

on nationwide case finding

campaign on ACF

69 Video conference workshop 04.01.2017 04.01.2017 1 87

on Active Case Finding for

DTO’s, Medical officers, STS,

STLS under ECHO project

70 Sensitization programme for 16.01.2017 16.01.2017 1 18

medical students of Mulana

Azad Medical college under

RNTCP

71 Training cum observatory 19.01.2017 19.01.2017 1 38

program on Active Case

Finding survey by Central

TB Division under RNTCP

72 Inauguration for Active Case 23.01.2017 23.01.2017 1 173

Finding (ACF) campaign via

ECHO project

73 RNTCP Modular Training 23.01.2017 03.02.2017 10 11

programme for Lab.

Technicians working under

Delhi Government

Dispensaries

74 RNTCP sensitization for 27.01.2017 27.01.2017 1 14

Nursing Students for Bsc (H)

1st year from Holy Family

School of Nursing

75 Meeting on active case 01.02.2017 01.02.2017 1 178

finding (ACF) via ECHO

programme to share

experiences for the campiagn

and suggestion under RNTCP

76 Nationwide video conference 08.02.2017 08.02.2017 1 152

workshop on Active Case

Finding under RNTCP

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77 RNTCP sensitization of 03.02.2017 03.02.2017 1 22

Nursing Students from Bsc (H)

1st year students from Holy

Family School of Nursing

78 Training cum workshop 13.02.2017 13.02.2017 1 28

program for VIHAN

Volunteers on Active Case

Finding survey programme

for Red light Area under

RNTCP

79 Training cum workshop 14.02.2017 14.02.2017 1 28

program for VIHAN

Volunteers & Area

coordinators of DSACS on

Active Case Finding survey

program for Red light Area

under RNTCP

80 Sensitization programme for 15.02.2017 15.02.2017 1 67

medical students of Mulana

Azad Medical college under

RNTCP

81 Active Case finding among 20.02.2017 20.02.2017 1 11

PLHIV in high risk group area

82 Training of Data Entry 21.02.2017 21.02.2017 1 12

operators (DEO’s) on new

modules in Nikshay portal

83 Training of Data Entry 23.02.2017 23.02.2017 1 11

operators (DEO’s) on new

modules in Nikshay portal

84 Sensitization on active case 23.02.2017 23.02.2017 1 37

finding activity in high risk

population

85 Sensitization on World TB 08.03.2017 08.03.2017 1 34

Day Celebration activities

and review meeting on

quarterly performance of

Delhi State

86 Review of Active case finding 14.03.2017 14.03.2017 1 9

campaign in G.B.Road area

under RNTCP programme

87 PMDT review meeting of 16.03.2017 16.03.2017 1 38

Delhi State under RNTCP

programme

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88 Sensitization programme for 17.03.2017 17.03.2017 1 19

medical Students of Mulana

Azad Medical college under

RNTCP

89 RNTCP Modular Training 20.03.2017 30.03.2017 10 9

programme for Lab.

Technicians working under

Delhi Government

Dispensaries

90 Final meeting on active 31.03.2017 31.03.2017 1 11

case finding (ACF) among

CSW at GB road under

RNTCP

  Total     115 2439

Personnel trained/ Sensitizated under RNTCP during 2016-17 of

New Delhi TB Centre

Training for various Category No. of No. of No. of

Training Days Participants

batches training attended

done training

DTOs and Medical Officers 13 13 838

Senior TB Supervisors (STS) 9 9 230

Senior TB Lab Supervisors (STLS) 6 6 183

Laboratory Tech. 4 29 61

Dot Providers 3 3 66

Nursing Staff 9 9 198

Data Entry Operators (DEOs) 2 2 23

DRTB Supervisors 9 9 77

Medical Students 11 11 488

Others Staff 24 24 275

Total 90 115 2439

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90 training sessions were conducted at New Delhi TB Centre-STDC

in 115 days and 2439 personnel, which included programme

managers, Medical officers, ground level RNTCP staff (STS/STLS, lab

technician, Data entry operator), Nurses, Para-medicals, PG-Students

and interns from various government as well as private institutions

were trained / sensitized on various aspects of RNTCP.

Analysis of Quarterly Cohort Reports

Compilation and preparation of quarterly reports (Sputum Conversion,

Treatment Outcome and Programme management) of all chest clinics

under RNTCP of Delhi state and their feedback is one of the major

activities of STDC. The analysis of the quarterly report for each chest

clinic in Delhi is carried out and the feedback, which includes

necessary instructions for improvement is prepared and are discussed

at the quarterly review meetings with the District TB Officers. All

these feedbacks and complied reports of the state are sent to the

DTOs and copies of these are also submitted to State TB Control

Officer and to Central TB Division, Ministry of Health & Family Welfare.

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Chest Clinic wise performance of RNTCP in Delhi State: CASE NOTIFICATION

IN 2016 from Public Sector

S. Chest Clinic Papulatuion TB Pulmo- % Extra % New TB % New Previously %No. (Lakhs) Patients nary Pulmo- Pulmo- Extra Case TB Case Treated Previously

notified nary nary Pulmo- Treatedfrom nary

publicSector

1 Bijwasan 9.5 1620 957 59 663 41 1247 77 373 23

2 BJRM 5.3 1685 1023 61 662 39 1313 78 372 22

3 BSA Rohini 5.7 2477 1418 57 1059 43 2059 83 418 17

4 Ch Desraj Rohini 5.7 1584 965 61 619 39 1271 80 313 20

5 DDU 11.4 3564 1943 55 1621 45 2873 81 691 19

6 GTBH 5.9 2213 1247 56 966 44 1733 78 480 22

7 Gulabi Bagh 9.8 703 383 54 320 46 573 82 130 18

8 Hedgewar 5.1 717 365 51 352 49 575 80 142 20

9 Jhandewalan 5.8 1290 748 58 542 42 913 71 377 29

10 Karawal Nagar 8.2 3804 2042 54 1762 46 3027 80 777 20

11 KCC 7.9 1690 1021 60 669 40 1337 79 353 21

12 LNH 5.3 863 448 52 415 48 674 78 189 22

13 NITRD 10 1959 1241 63 718 37 1608 82 351 18

14 Malviya ngr 5.3 2682 1644 61 1038 39 2168 81 514 19

15 Moti Nagar 6.3 4049 2339 58 1710 42 3125 77 924 23

16 Narela 6.4 2423 1566 65 857 35 1826 75 597 25

17 NDMC 7 2736 1626 59 1110 41 2139 78 597 22

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18 Nehru Nagar 11.4 5045 3018 60 2027 40 3959 78 1086 22

19 Patparganj 8.1 3518 2036 58 1482 42 2859 81 659 19

20 R.K.Mission 8.4 494 322 65 172 35 371 75 123 25

21 RTRM 5.5 1714 1073 63 641 37 1352 79 362 21

22 SGM 7.3 2180 1245 57 935 43 1780 82 400 18

23 Shahdara 6.3 2162 1173 54 989 46 1592 74 570 26

24 SPM 6.5 951 536 56 415 44 679 71 272 29

25 JPC Hospital 5.7 3534 1645 47 1889 53 2687 76 847 24

Total  179.8 55657 32024 57.76 23633 42.24 43740 78.24 11917 21.76

26 DTBA’s Pavement Homeless

Dwellers Project People 102 97 95 5 5 63 62 39 38

A total 179.8 lakh population was covered by 25 Chest clinics operating in Delhi and 55657 TB

patients were notified from public sector during 2016. Out of which 32024 (57.5%) were pulmonary

TB cases and 23,633 (42.5%) were extra pulmonary TB cases. In all, 43740 new TB cases were

notified from Delhi State from all the chest clinics.

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Chest Clinic wise annual performance of RNTCP in Delhi State:

CASE NOTIFICATION IN 2016 from Private Sector

S. Chest Clinic TB % TB Total Annual Annual Total

No. Patients Patients TB Pts. TB Notifi- TB Annual

Notified Notified Notified cation Notifi- TB

from Pvt. from Pvt. Rate cation Notifi-

Sector Sector (Public Rate cation

from total Sector) (Private (Pub+

TB cases Sector) Prevate)

1 Bijwasan 0 0 1620 169 0 169

2 BJRM 122 7 1807 318 23 341

3 BSA Rohini 10 0 2487 432 2 434

4 Ch Desraj Rohini 1135 42 2719 276 198 474

5 DDU 80 2 3644 311 7 318

6 GTBH 29 1 2242 372 5 377

7 Gulabi Bagh 49 7 752 71 5 76

8 Hedgewar 43 6 760 141 8 149

9 Jhandewalan 88 6 1378 220 15 235

10 Karawal Nagar 0 0 3804 462 0 462

11 KCC 56 3 1746 213 7 220

12 LNH 231 21 1094 164 44 208

13 LRS 1416 42 3375 196 141 337

14 Malviya ngr 381 12 3063 507 72 579

15 Moti Nagar 784 16 4833 637 123 760

16 Narela 35 1 2458 381 6 387

17 NDMC 510 16 3246 389 72 461

18 Nehru Nagar 266 5 5311 442 23 465

19 Patparganj 144 4 3662 435 18 453

20 R.K.Mission 1052 68 1546 58 124 182

21 RTRM 201 10 1915 312 37 349

22 SGM 32 1 2212 299 4 303

23 Shahdara 79 4 2241 344 13 357

24 SPM 97 9 1048 147 15 162

25 JPC Hospital 209 6 3743 617 36 653

Total  7049 11.56 62706 7913 998 8911

26 DTBA’s Pavement — — 102 25 — 25

Dwellers Project

Case notification from Private sector across Delhi State is a major concern underRNTCP. During 2016, 7049 tuberculosis cases were notified from private sectoracross all the 25 chest clinics of Delhi State. About 12% cases were detected fromthe private sector of the total TB cases notified during 2016 from Delhi State fromthe total TB cases. Annual case notification rate was 357 of which 317 was frompublic sector and 40 was from private sector.

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Chest Clinic-wise annual performance of RNTCP in Delhi State :

Diagnosed cases (Clinical & Microbiological in 2016)

S. Chest Clinic Micrro- % Micrro- Clinically % Pediatrict %

No. biological biological Diagnosed Clinically TB Pediatrict

Confirmed Confirmed Diagnosed TB

1 Bijwasan 677 42 943 58 150 9

2 BJRM 680 40 1005 60 177 11

3 BSA Rohini 809 33 1668 67 278 11

4 Ch Desraj Rohini 586 37 998 63 232 15

5 DDU 1273 36 2291 64 445 12

6 GTBH 818 37 1395 63 272 12

7 Gulabi Bagh 253 36 450 64 88 13

8 Hedgewar 274 38 443 62 87 12

9 Jhandewalan 494 38 796 62 172 13

10 Karawal Nagar 1240 33 2564 67 491 13

11 KCC 665 39 1035 61 155 9

12 LNH 267 31 596 69 135 16

13 LRS 871 44 1088 56 188 10

14 Malviya ngr 1136 42 1546 58 310 12

15 Moti Nagar 1426 35 2623 65 467 12

16 Narela 992 41 1431 59 233 10

17 NDMC 1086 40 1650 60 271 10

18 Nehru Nagar 1905 38 3140 62 539 11

19 Patparganj 904 26 2614 74 466 13

20 R.K.Mission 235 48 259 52 67 14

21 RTRM 842 49 872 51 144 8

22 SGM 592 27 1588 73 278 13

23 Shahdara 697 32 1465 68 304 14

24 SPM 350 37 601 63 122 13

25 JPC Hospital 838 24 2696 76 606 17

Total  19910 36.92 35757 63.08 6677 12.12

26 DTBA’s Pavement

Dwellers Project 85 83 17 17 — —

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As per latest treatment guideline under RNTCP in 2016, the treatment

indicators have been classified as microbiologically confirmed TB case

i.e. presumptive TB patient with biological specimen positive for AFB or

positive for MTB on culture or positive for TB through Quality Assured

Rapid Diagnostic molecular test. In 2016, a total of 19910 (37%)

microbiological confirmed TB cases were put on treatment from all the

25 chest clinics of Delhi.

Clinically diagnosed TB case wherein a presumptive TB case who is not

microbiologically confirmed but diagnosed active TB by a clinician on the

basis of X-rays, histopathology or clinical signs. In 2016, 35757 (63%)

were clinically diagnosed as TB cases from all the 25 chest clinics of

Delhi State.

Pediatric TB case which is based on the presence of abnormalities

consistence with TB on radiography, history of exposure to an infections

case, evidence of TB infection (Positive TST) and clinical findings

suggestive of TB in event of negative or unavailable microbiological results.

In 2016, a total of 6677 (12%) pediatric TB cases were diagnosed from all

the 25 chest clinics of Delhi State. Thus, in all a total of 62344

tuberculosis cases were diagnosed from all the 25 chest clinics of Delhi

State during 2016.

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SUPERVISORY ACTIVITIES

Monitoring and evaluation is an important tool for RNTCP. As State

TB Training & Demonstration Centre (STDC), the faculty of the Centre

is actively involved in monitoring and supervision of the TB control

programme at national and state level.

(A) State Internal Evaluation

The internal evaluation of all the chest clinics is an important activity

under the RNTCP where in all aspects of the clinic records, staff,

drug stores, microscopic activities, facilities and financial aspects are

evaluated in detail. Internal evaluation is organized by State TB

Control Department. Director of STDC or his nominee is the member

of internal evaluation team for all the chest clinics of Delhi. The

internal evaluation is carried out in two chest clinics of the state in

every quarter. During the year 2016-17, faculty from NDTB Centre

participated in evaluation of chest clinic as per the following schedule:

Faculty Date of Visits Chest Clinic

Dr. Shanker Matta 18th to 21st April, Shahdara Chest

2016 Clinic

(B) Supervisory Visits to Chest Clinics

Monitoring and supervision activities are implemented to ensure that

activities are conducted as planned, and that the data recorded and

reported is accurate and valid. It provides a feedback system for

remedial action to improve performance and in turn improve the

programme indicators. It also serves as a tool for continuous “on the

job sensitization” of the staff and increase the involvement and

commitment of the higher level authorities, both at the state and the

district level.

During the year 2016-17, the following Supervisory visits were made

by the doctors who gave their inputs to the improve programme

performance under RNTCP:

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Faculty Date of Visits Chest Clinic

Dr. Shanker Matta 11/4/2016 RKM Chest Clinic

Dr.K.K.Chopra 18/6/2016 BSA Chest Clinic

Dr.K.K.Chopra 25/6/2016 Ch. Des Raj Chest Clinic

Dr. K.K. Chopra 29/6/2016 BJRM Chest Clinic

Dr. Shanker Matta 13/7/2016 Shastri Park Chest Clinic

Dr. Shanker Matta 14/7/2016 Kingsway Camp Chest Clinic

Dr. Shanker Matta 27/9/2016 Bijwasan Chest Clinic

Dr.K.K.Chopra 24/1/2017 BSA Chest Clinic

Dr. K.K.Chopra 24/1/2017 Ch. Des Raj Chest Clinic

Dr. Shanker Matta 30/1/2017 Hedgewar Chest Clinic

Dr. Shanker Matta 30/1/2017 Shahdara Chest Clinic

Dr. K.K.Chopra 31/1/2017 BJRM Chest Clinic

Dr. K.K. Chopra 29/3/2017 Ch. Des Raj Chest Clinic

LIABRARY AND INFORMATION SERVICES

The website of New Delhi TB Centre (www.ndtbc.com) has information

about various facilities and activities undertaken by the Centre along

with list of publications from the institute since 1940. The Centre

maintains a library which has 660 books on various aspects related

to tuberculosis and chest diseases. In addition, it has various National

and International journals. The library renders its services to the

students of MAMC and V.P.Chest Institute as well as the faculty of

the Centre.

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(A) VISITORS TO NDTB CENTRE

1. Members of Board of Directors of FIND headquarters, Geneva

visited NDTB Centre on 13th April 2016. Dr. K.K. Chopra,

Director presented the activities of NDTB Centre and Dr. M

Hanif, Microbiologist briefed about the laboratory activities. This

was followed by discussion on role of FIND in establishing

laboratory network in India and its impact on TB situation.

They also made a visit to the laboratory.

2. A team of audit visited lab of NDTB Centre for review of paediatric

CBNAAT project on 25th April 2016. Activities of the project

were audited.

3. A team of Global Fund for audit of its activities in India visited

Delhi state on 26th April 2016. All the activities and records of

STDC and IRL were audited and discussed.

4. A team from FIND head office in Geneva visited the laboratory

of New Delhi TB Centre on 30th May 2016. The team reviewed

the laboratory activities in technical collaboration with FIND.

5. Two member team from NRL – NITRD comprising of One

Microbiologist and One Laboratory Technician visited laboratory

for three days for Annual On- Site Evaluation from 15th – 17th

June, 2016.

6. A team from NRL – NITRD, Mehrauli comprising of two

Microbiologist visited laboratory on 9th September, 2016 for

laboratory evaluation.

7. Dr. Paul Arthu Jensen from Centre for Global Health visited

the laboratory of the Centre on 20th October 2016. During the

visit he reviewed about bio safety in laboratory and gave

recommendations on infection control in the laboratory.

8. Two days laboratory assessment visit on 23rd – 24th November,

2016 was carried out by Dr. Sanjeev Saini, Microbiologist from

ADMINISTRATION

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FIND.

9. Two microbiologists and two Lab. Technician of Jamia Medical

College visited laboratory of NDTB Centre on 27th Feb, 2017.

They were briefed about the processes of case detection and

Drug Sensitivity testing procedures adopted under RNTCP.

10. A team of NABL assessors visited laboratory of NDTB Centre for

conducting Pre assessment on accreditation of the laboratory

on 3rd and 4th February, 2017. They assessed infrastruction

and Human Resources of the laboratory and inspected the SOPs

and calibration of laboratory equipments. They suggested some

non-conformities to be completed in one month before visit by

NABL accreditation team.

11. A team of Afghanistan TB Officials accompanied by Dr. Sundari

from WHO visited laboratory on 6th March, 2017 for understanding

TB diagnosis and control programme under RNTCP.

12. A team of international and national parliamentarians visited

NDTB Centre on 7th March 2017. The visit was organised by

The Union. The purpose of the visit was to familiarize the

honourable parliamentarians with advanced TB diagnostic and

treatment services available in India and to familiarize them

with the basic diagnostic and treatment facilities available at

the district and sub –district level. Dr. K.K. Chopra, Director

and Dr. M. Hanif, Microbiologist briefed them about the

structure of TB control in India and laboratory diagnostic

facilities available at the state level.

(B) GRANTS

i. During the year 2016-17, the Government of India, Ministry of

Health & Family Welfare released the annual recurring grant-

in-aid (Salaries) of Rs. 310 Lacs and grant-in-aid (General) of

Rs. 37.34 Lacs.

ii. Rs. 10,000/- was provided by Tuberculosis Association of India

as annual grant.

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(C) DONATIONS

Donations received (through TAI) for medicines

- (Anar Singh Chanchal Singh Memorial Fund Rs. 12,490/-

- Smt. Ram Piyari Dutt Memorial Fund

- Donation, Interest on FDR and saving Rs. 41,545/-

Bank Account

Total Rs. 54,035/-

(D) RIGHT TO INFORMATION ACT 2005

During 2016-17, 46 applications have been received under RTI Act,

2005. The table gives the details of applications received and disposed.

Table: Details of yearly Receipts & Disposal of RTI applications

for 2016-17

S. Month & RTI Applications Appeal Amount

No. Year of Fee

Paid

No. of No. of In No. of No. of In

RTI RTI Process Appeals Appeals Pro-

applica- applica- received disposal cess

tions tions

received disposal

1 April, 16 11 11 - - - - -

2 May,16 5 5 - - - - -

3 June,16 1 1 - - - - -

4 July, 16 11 11 - - - - -

5 August, 16 4 4 - - - - -

6 Sept, 16 1 1 - - - - -

7 Oct, 16 2 2 - - - - -

8 Nov,16 5 5 - - - - -

9 Dec,16 3 3 - - - - -

10. Jan,17 2 2 - - - - -

11. Feb,17 1 1 - - - - -

Total 2016-17 46 46 - - - - -

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An insight of annual statistics of the Center are as follows:

Outpatient Attendance

New outpatients attendance 10157

Revisits 9895

Total outpatients attendance 20052

DOT Centre Attendance

New Patient put on DOTS at NDTB DOT Centre 17

Total Patients (2015-16) put on DOTS at NDTB 455

DOT Centre

Special Clinics Attendance

Special clinics (TB and Diabetes, HIV and TB, COAD 562

and Tobacco Cessation Clinic- Total New+old cases

Laboratory Examinations

Total laboratory examinations 35782

Total Smear Examination 35782

3. Culture Examination

(a) Solid Culture 5725

(b) Liquid Culture 4860

4. Drug susceptibility test

(a) by solid culture method 215

(b) by Liquid Culture Method 1062

(c) by LPA 5066

SUMMARY OF ACTIVITIES OF

NEW DELHI TB CENTRE

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5 CBNAATa.

Examinations 13363

Tuberculin skin tests

Total Tuberculin skin tests done 8425

Tests read 7451

Reactors (>10mm) 3352

Non-reactors (<10mm) 4099

Radiological Examinations

Radiological Examinations 1561

Trainings/IRL Visits/Publications

Personnel trained 2439

Supervision and Monitoring /Internal 14

Evaluation of Chest Clinics

IRL Visits to chest clinics for EQA 21

Presentations of papers in conference 6

Research and Publications 7

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THAKUR, VAIDYANATH AIYAR & CO. 221-223, Deen Dayal Marg, New Delhi-02

Chartered Accountants Phones : 91 - 11-23236958-60, 23237772

New Delhi, Mumbai, Kolkata, Chennai Fax : 91 - 11-23230831

Patna and Chandigarh Email : [email protected]

: [email protected]

Independent Auditor’s Report

To the Members of

New Delhi Tuberculosis Center,

We have audited the accompanying financial statements of New Delhi

Tuberculosis Center which comprise the Balance Sheet as at March

31, 2017, the Statement of Income and Expenditure for the year

then ended, and a summary of significant accounting policies and

other explanatory information.

Management’s Responsibility for the Financial Statements

Management is responsible for the preparation of these financial

statements that give a true and fair view of the financial position and

financial performance of the Centre in accordance with the Accounting

Standards, to the extent applicable, issued by the Institute of

Chartered Accountants of India. This responsibility includes the

design, implementation and maintenance of internal control relevant

to the preparation and presentations of the financial statements that

gives a true and fair view and are free from material misstatement,

whether due to fraud or error.

Auditor’s Responsibility

Our responsibility is to express an opinion on these financial

statements based on our audit. We conducted our audit in accordance

with the Standards on Auditing issued by the Institute of Chartered

Accountants of India. Those Standards require that we comply with

ethical requirements and plan and perform the audit to obtain

reasonable assurance about whether the financial statements are

free from material misstatement.

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An audit involves performing procedures to obtain audit evidence

about the amounts and disclosures in the financial statements. The

procedures selected depend on the auditor’s judgment, including

the assessment of the risks of material misstatement of the financial

statements, whether due to fraud or error. In making those risk

assessments, the auditor considers internal control relevant to the

Centre in preparation and fair presentation of the financial statements

in order to design audit procedures that are appropriate, but not for

the purpose of expressing an opinion on the effectiveness of the

Entity’s internal control. An audit also includes evaluating the

appropriateness of accounting policies used and the reasonableness

of the accounting estimates made by management, as well as

evaluating the overall presentation of the financial statements. We

believe that the audit evidence we have obtained is sufficient and

appropriate to provide a basis for our audit opinion.

Opinion

In our opinion and to the best of our information and according to

the explanations given to us, the financial statements read with

accounting policies and Notes given in Schedule 17 give the

information required by the Act in the manner so required and give a

true and fair view in conformity with the accounting principles

generally accepted in India:

a) in the case of the Balance Sheet, of the state of affairs of

the Centre as at March 31, 2017 and

b) in the case of the Statement of Income and Expenditure,

of the Surplus for the year ended on that date;

Report on Other Legal and Regulatory Requirements

a) We have obtained all the information and explanations

which to the best of our knowledge and belief were

necessary for the purpose of our audit;

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b) In our opinion, proper books of account as required by

law have been kept by the Centre so far as appears from

our examination of those books;

c) The Balance Sheet , Statement of Income and

Expenditure dealt with by this Report are in agreement

with the books of account;

d) In our opinion, the Balance Sheet, Statement of Income

and Expenditure comply with the Accounting Standards,

to the extant applicable, issued by the Institute of

Chartered Accountants of India.

For Thakur, Vaidyanath Aiyar & Co.

Chartered Accountants

FRN: 000038N

(Anil K. Thakur)

Partner

M. No. : 088722

Place: New Delhi

Date : 28.09.2017

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NEW DELHI TUBERCULOSIS CENTRE

BALANCE SHEET AS AT 31ST MARCH, 2017

Schedule As at As at

31.03.2017 31.03.2016————— ————— —————

(Rs.) (Rs.)

SOURCES OF FUNDS:

Assets Fund 1 3,372,606 3,518,730

Earmarked Funds 2 1,312,350 1,392,596

Current Liabilities and Provisions 3 4,793,769 6,094,812

Accumulated Deficit / Surplus 310,593 194,928

—————— ——————

Total 9,789,318 11,201,066

—————— ——————

APPLICATION OF FUNDS:

Fixed Assets 4 3,372,606 3,518,730

Current Assets, Loans & Advances 5 6,270,405 7,567,879

TDS recoverable 146,307 114,457

—————— ——————

Total 9,789,318 11,201,066

—————— ——————

Accounting Policies and Notes 17

to the accounts

Schedule Nos.1 to 17 form an integral part of the Accounts

As per our report of even date attached

For Thakur Vaidyanath Aiyer & Co.

Chartered Accountants

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NEW DELHI TUBERCULOSIS CENTRE

STATEMENT OF INCOME AND EXPENDITURE FOR THE YEAR

ENDED 31ST MARCH 2017

Schedule For the year For the year 2016-17 2015-16

————— ————— ————— (Rs.) (Rs.)

INCOME

Recuring Grant from Govt.of India :

Grant-in-aid Salaries 31,000,000 30,400,000

Grant-in-aid General 3,734,000 3,300,000

Maintenance Grants from TAI 10,000 10,000

Fees from Patients 6 291,900 452,095

Misc. Receipts:

- Interest income 152,196 353,188

- Other receipts 1,270 30—————— ——————

Total 35,189,366 34,515,313—————— ——————

EXPENDITURE

Salary & Other Staff expenditure 7 30,880,412 30,319,752

Administrative Expenses 8 3,911,053 3,553,712

Expenses on X-Ray Films, Drugs

& Medicines and Lab. Consumable 9 282,236 416,186—————— ——————

Total 35,073,701 34,289,650—————— ——————

(Deficit)/Surplus for the year 115,665 225,663

Less / (Add) : Balance as per last account 194,928 (30,735)—————— ——————

310,593 194,928—————— ——————

Accounting Policies and Notes 17to the Accounts

Schedule Nos.1 to 17 form an integral part of the Accounts

As per our report of even date attached

For Thakur Vaidyanath Aiyer & Co.

Chartered Accountants

Accountant

(S.K. Saini)

Director

( Dr.K.K.Chopra)

(Anil K. Thakur) Chairman

Partner (Dr. L.S. Chauhan)

M. No. 088722

Place : New Delhi

Date : 28.09.2017

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NEW DELHI TUBERCULOSIS CENTRE

RECEIPTS & PAYMENTS ACCOUNT FOR THE YEAR

ENDED MARCH 31, 2017

Schedule For the Year For the Year

2016-17 2015-16————— ————— —————

R E C E I P T S Rs.

Opening Cash & Bank Balances 5 7,396,262 6,420,045

Grants :

Recurring Grant-in Aid from

Govt. of India

- Grant-in-aid Salaries 31,000,000 30,400,000

- Grant-in-aid General 3,734,000 3,300,000

Maintenance Grants from TAI 10,000 10,000

Fee from Patients 6 291,900 444,545

Receipts from TAI 10 2,093,000 2,062,363

Other Receipts 11 520,197 1,813,428—————— ——————

Total 45,045,359 44,450,381—————— ——————

P A Y M E N T S

Staff Expenditure 12 30,764,262 30,250,711

Administrative expenses 13 4,036,912 3,626,918

X-Ray films,Drugs and Med. & 14 277,795 491,757

Lab. Consumables

Payments from TAI Fund 15 2,093,000 2,062,363

Other Payments 16 1,753,878 622,370

Closing Cash & Bank Balances 5 6,119,512 7,396,262—————— ——————

Total 45,045,359 44,450,381—————— ——————

Policies and Notes to the Accounts 17

Schedule Nos.1 to 17 form an integral part of the Accounts

As per our report of even date attached

For Thakur Vaidyanath Aiyer & Co.

Chartered Accountants

Accountant

(S.K. Saini)Director

( Dr.K.K.Chopra)

(Anil K. Thakur) ChairmanPartner (Dr. L.S. Chauhan)

M. No. 088722Place : New DelhiDate : 28.09.2017

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NEW DELHI TUBERCULOSIS CENTRE

Schedule- 1

ASSETS FUND

As at As at

31.03.17 31.03.16

————— —————

(Rs.) (Rs.)

Balance as Per last A/c 3,518,730 4,666,162

Add : Additions during the year for Cost

of Assets Acquired (refer Schedule-4) 305,056 482,537

—————— ——————

38,23,786 5,148,699

—————— ——————

Less:

Disposals during the year - 1,161,239

Depreciation for the year 451,180 468,730

(refer Schedule - 4)

—————— ——————

Total 3,372,606 3,518,730

—————— ——————Schedule - 2

Unutilised Received / Interest Total Utilised Unutilised Balance Transferred during Balance

as on during the year as on 01.04.16 the year 31.03.17

(Rs.) (Rs.) (Rs.) (Rs.) (Rs.) (Rs.)

EARMARKED FUND

General Donations 336,073 10,000 41,720 387,793 - 387,793

Auditorium fund 114,893 10,000 - 124,893 123,885 1,008

For Poor Patients 56,566 - - 56,566 - 56,566

For Medicines 303,410 12,490 - 315,900 33,953 281,947

Staff Welfare Fund 83,054 - 3,382 86,436 - 86,436

Research Fund 498,600 - - 498,600 - 498,600

Total 1,392,596 32,490 45,102 1,470,188 157,838 1,312,350

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NEW DELHI TUBERCULOSIS CENTRE

As at As at

31.03.17 31.03.16

————— —————

(Rs.) (Rs.)

Schedule- 3

Current Liabilities & Provisions

Advance Fee & Lab Charges 3,160 3,160

Salary & Allowances 2,712,532 2,478,599

Bonus 178,870 89,653

Other Payable 32,667 61,968

Sundry Creditors 17,415 121,897

Provision for Contribution to Gratuity Fund 205,000 412,000

Security Deposit 29,330 22,344

Unspent Project Balances :

Unspent Project Fund -SMS for Sure 929,153 1,573,953

Unspent Project Fund -Acceleration of TB notification 80,921 221,075

Unspent Project Fund -Framework of Tb care in prison 241,500 241,500

Unspent Project Fund -Genetic Polymprphism - 30,000

Unspent Project Fund -Xpert Ultra 363,221 838,663

—————— ——————

Total 4,793,769 6,094,812

—————— ——————

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NEW DELHI TUBERCULOSIS CENTRE

Schedule - 4

Fixed Assets

WDV Additions Disposals Balance Depreciation Net

balance

as on during the year as on for the year on

01.04.16 31.03.17 31.03.17

————— ————— ————— ————— ————— —————

(Rs.) (Rs.) (Rs.) (Rs.) (Rs.) (Rs.)

Building 245,966 - - 245,966 24,597 221,369

Electrical 796,062 - - 796,062 79,606 716,456

Installations and

Sanitary Fittings

Furniture & 1,081,926 292,485 - 1,374,411 125,415 1,248,996

Fittings

Lab. Equipments 637,235 - - 637,235 95,585 541,650

X-ray Equipments 559,384 - - 559,384 83,908 475,476

Other Equipments 18,748 - - 18,748 2,812 15,936

Computer 18,926 12,571 - 31,497 15,127 16,370

Books 126 - - 126 76 50

Vehicle 160,357 - - 160,357 24,054 136,303

_________ _________ _________ _________ _________ _________

Total 3,518,730 305,056 - 3,823,786 451,180 3,372,606_________ _________ _________ _________ __________________

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NEW DELHI TUBERCULOSIS CENTRE

As at As at

31.03.17 31.03.16

————— —————

(Rs.) (Rs.)

Schedule- 5

Current Assets & Loans and Advances

Stocks and Stores at cost :

(as valued and certified by the

Management)

-X-Ray films and chemicals 26,484 4,613

-Laboratory stains, chemicals glassware 88,409 1,18,315

Festival Advance 36,000 46,800

Universal Comfort Products Ltd - 1,889

————— —————Sub Total - A 150,893 171,617

————— —————

Cash and Bank Balances:

Cash in hand 2,870 290

(as certified by the Management)

In Current A/c with BOI 4,826,191 6,081,388

In Saving Bank

- with BOI ( Earmarked donation fund) 1,204,015 1,231,530

- with BOI (Staff Welfare Fund) 86,436 83,054

————— —————Sub Total - B 6,119,512 7,396,262

————— —————Gross Total - A+B 6,270,405 7,567,879

————— —————

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NEW DELHI TUBERCULOSIS CENTRE

Advance Fee Add: Advance Fee for Advance

Fee Received fee adjusted the year as on

as on During During 2016-17 31.03.2017

01.04.16 the year the year

————— ————— ————— ————— —————

(Rs.) (Rs.) (Rs.) (Rs.) (Rs.)

Schedule-6

Advance Fees for patients

Laboratory 3,160 291,900 - 291,900 3,160

charges

X-ray charges - - - -

———–— ———–— ———— —–——— —————

Total 3,160 291,900 - 291,900 3,160

———–— ———–— ———— —–——— —————

For the year For the year

2016-17 2015-16

—————— ——————

(Rs.) (Rs.)

Schedule- 7

Salary & Other Staff Expenditure :

Salaries 9,849,117 10,850,949

Dearness Allowance 12,450,805 11,142,854

House Rent Allowance 2,866,947 2,774,027

Transport Allowance 1,792,848 1,720,282

Other Allowances 666,545 600,186

Children’s Education Allowances 333,700 343,252

Contribution to Provident Fund 2,212,268 2,152,950

Contribution to Gratuity Fund 205,000 412,000

Bonus 355,924 89,653

Travel Concession 147,258 233,599————–—— ————–——

Total 30,880,412 30,319,752————–—— ————–——

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NEW DELHI TUBERCULOSIS CENTRE

For the year For the year

2015-16 2014-15

—————— ——————

(Rs.) (Rs.)

Schedule- 8

Administrative Expenses :

Wages to Contractual staff 871,542 823,625

Wages toTemporary staff - 95,288

Security Charges 707,448 533,868

Staff Uniform 13,025 10,834

Medical Aid to staff 263,389 248,468

Travelling Expenses & Conveyance 28,104 48,865

Repairs to Furniture and equipment 121,535 85,244

Repairs to X-ray equipments 41,375 36,042

Repairs to Laboratory equipment 95,665 34,738

Telephone Expenses 130,658 131,290

Printing & Stationery 92,399 90,360

Postage 5,615 3,825

Laundry Charges 5,610 3,298

Books & Journals 860 -

Maintenance of car 40,294 39,184

Audit Fee 24,780 24,255

Miscellaneous expenses 107,953 95,393

Building maintenance expenses-civil 803,263 546,359

Building maintenance expenses-electrical 179,400 -

Annual day expenses 38,478 195,799

Legal expense 19,800 22,550

Linen and bedding - 1,890

Cost of Asets Aquired out of Grant 319,860 482,537

Fund Fund & Furniture Repairs etc————–—— ————–——

Total 3,911,053 3,553,712————–—— ————–——

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NEW DELHI TUBERCULOSIS CENTRE

For the year For the year

2016-17 2015-16

——————— ——————

(Rs.) (Rs.)

Schedule- 9

X-Ray Films ,Drugs and Medicines & Lab. Consumable

Drugs and Medicines

Balance as on 1.4.2016 -

Add : Purchased during the year 44,837

——————Less : Closing Stock - 44,837 48,150

——————

X-Ray Films and Chemicals

Balance as on 1.4.2016 4,613

Add : Purchased during the year 105,028

——————

109,641

Less : Closing Stock 26,484 83,157 1,01,843——————

Lab. Stains, Chemicals & Glassware

Balance as on 1.4.2016 118,315

Add : Purchased during the year 124,336

——————

242,651

Less : Closing Stock 88,409 154,242 266,193

——————

——————— ——————

Materials Consumed Total 282,236 416,186——————— ——————

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NEW DELHI TUBERCULOSIS CENTRE

For the year For the year

2016-17 2015-16

——————— ———————

Schedule- 10 (Rs.) (Rs.)

Receipts from TAI

For PF Advances 2,093,000 772,000

For Gratuity Payments - 335,054

For PF Payments - 955,309

——————— ———————Total 2,093,000 2,062,363

——————— ———————Schedule - 11

Other Receipts

Recovery of Festival Advance 69,300 62,100

Donations for Medicines 12,490 13,493

Staff Welfare Fund 3,382 3,224

Interest on FFD A/c 128,433 353,188

Interest on Saving A/c (Earmarked Fund ) 33,633 46,430

General Donation 10,000 -

Miscellaneous Receipts 1,270 30

Earnest money 25,000 -

Auditorium Fund 10,000

Project-Genetic Polymorphism - 30,000

Project-Acceleration of TB notification 224,800 224,800

Project-Framework of TB.care in prisons - 241,500

Project-Xpert Ultra - 838,663

universal comfort products ltd. 1,889 -——————— ———————

Total 520,197 1,813,428

——————— ———————

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NEW DELHI TUBERCULOSIS CENTRE

For the year For the year

2016-17 2015-16——————— ———————

Schedule- 12 (Rs.) (Rs.)

Staff Expenditure

Salaries 9,680,549 10,838,531

Dearness Allowance 12,455,119 10,867,447

House Rent Allowance 2,859,047 2,762,539

Transport Allowance 1,796,347 1,699,587

Other Allowances 614,978 595,399

Children’s Education allowance 333,700 343,252

Contribution to Provident Fund 2,198,557 2,123,277

Contribution to Gratuity Fund 412,000 695,000

Bonus 266,707 92,080

Travel Concession 147,258 233,599

——————— ———————

Total 30,764,262 30,250,711

——————— ———————

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NEW DELHI TUBERCULOSIS CENTRE

For the year For the year

2016-17 2015-16——————— ———————

Schedule- 13 (Rs.) (Rs.)

Administrative Expenses

Wages to Contractual staff 945,071 798,447

Wages to Temporary staff - 118,034

Security Charges 753,412 530,905

Staff Uniform 9,591 10,834

Medical Aid to staff 263,389 248,468

Travelling Expenses & Conveyance 28,104 48,865

Repairs to Furniture and equipment 121,535 85,244

Repairs to X- Ray equipment 41,375 36,042

Repairs to Laboratory equipment 93,414 35,755

Telephone Expenses 135,649 129,790

Printing & Stationery 92,399 90,360

Postage 5,615 3,825

Laundry Charges 5,610 3,298

Books & Journals 860 -

Maintenance of car 29,764 41,217

Audit Fee 24,150 24,045

Miscellaneous expenses 107,953 95,393

Building maintenance -civil 798,933 534,015

Building maintenance -Electrical 179,400 31,066

Annual day expenses 38,478 195,799

Furniture 319,860 484,426

Legal expenses 42,350 79,200

Linen and bedding - 1,890——————— ———————

Total 4,036,912 3,626,918——————— ———————

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NEW DELHI TUBERCULOSIS CENTRE

For the year For the year

2016-17 2015-16——————— ———————

Schedule- 14 (Rs.) (Rs.)

X-Ray Films, Drugs and Medicines

& Lab. Consumable

X-Ray Films and Chemicals 105,028 103,462

Drugs and Medicines 44,837 48,150

Laboratory Stains and Chemicals 127,930 340,145——————— ———————

Total 277,795 491,757——————— ———————

Schedule- 15

Payments from TAI Fund

PF Advances 2,093,000 772,000

Gratuity Payments - 335,054

PF Payments - 955,309——————— ———————

Total 2,093,000 2,062,363——————— ———————

Schedule- 16

Other Payments

Festival advance 58,500 67,500

Earnest money - -

General donation - -

Staff Welfare Fund - -

Donation fo medicines 33,953 36,692

Auditorium funds 123,885 88,406

Ptoject-SMS for sure 644,800 426,047

Project-Acceleration of TB notification 364,954 3,725

Project-Xpert Ultra 475,442 -

Project Genetic Polymorphism 30,000 -

Security deposit 22,344 -——————— ———————

Total 1,753,878 622,370——————— ———————

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NEW DELHI TUBERCULOSIS CENTRE

Annexure 1 (for the year ended 31st March 2017)

Grant-in-aid Grant-in-aid

Salaries General

——————— ———————

(Rs.) (Rs.)

INCOME

Opening suplus/(Deficit) (01.04.16) (6,675) 201,603

Grant-in-aid from Govt.of India 31,000,000 3,734,000

Maintenance Grants from TAI - 10,000

Fees from Patients - 291,900

Interest income - 152,196

Other receipts - 1,270

——————— ———————Total 30,993,325 4,390,969

——————— ———————

EXPENDITURE

Salary & Other Staff expenditure 30,880,412 -

Administrative Expenses - 3,911,053

Expenses on X-Ray Films, Drugs & Medicines

and Lab. Consumable - 282,236

——————— ———————

Total 30,880,412 4,193,289——————— ———————

Surplus/(Deficit) 112,913 197,680———————

Total Surplus as on 31.03.3017 310,593

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NEW DELHI TUBERCULOSIS CENTRE

Schedule – 17

Significant Accounting Policies and Notes to Accounts

A. Significant Accounting Policies :

1. Accounting Convention :

The Financial Statements have been prepared on accrual basis (except

as specifically stated) and under the historical cost convention, and in

accordance with the generally accepted accounting principles in India.

2. Use of Estimates:

The preparation of the Financial Statements in conformity with GAAP

in India requires management to make estimates and assumptions,

wherever necessary, that affect the reported amount of assets and

liabilities and contingent liabilities as at the date of financial statements

and the amount of revenue and expenses during the year. Actual results

could differ from those estimates. Any revision to such estimates is

recognized in the year in which the results are known / materialized.

3. Revenue Recognition :

Income & Expenditures have been accounted for on accrual basis

except for leave encasement.

4. Fixed Assets & Depreciation:

a) Fixed Assets are stated at cost, Assets received as donation

are stated at estimated market value on the date of

donation.

b) Centre has started charging Depreciation from the

Financial Year 2011-12 on its Fixed Assets as per rate

prescribed under Income Tax Act, 1961.

c) Further, Depreciation has been debited to the Assets

Fund by Crediting Cost of respective Fixed Assets.

d) Capital items having cost / value less than Rupees Five

Thousand are not capitalized.

e) Assets Fund has been credited with the cost/value of

Fixed Assets acquired during the year by debiting Income

& Expenditure account and / or Project Fund.

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5. Inventories :

Laboratory stains, chemicals and glassware and x-ray films & chemicals

are valued at purchase price following FIFO method (Refer Note No. 3).

6. Gratuity :

Liability for future payments of Gratuity has been provided for as per

the rules of Tuberculosis Association of India (TAI) and said Gratuity

Fund is also maintained by TAI.

7. Provident Fund :

As per rules of Tuberculosis Association of India (TAI), accounts relating

to Provident Fund of the staff of the Centre have been maintained by

the (TAI).

8. Interest Incomes :

Interests earned on the Investments of Earmarked Funds have been

credited directly to such Fund instead of Income & expenditure

Account.

B. Notes to Accounts

1. In absence of any demands from Lok Nayak Hospital for

Electricity and water expenses no liabilities have been provided

till the financial year 2015-16. However, from 2016-17 Lok Nayak

Hospital started raising bills for electricity charges only.

2. Title deed of the land on which Buildings are situated is not

available.

3. Cost / Value of stock are as valued and verified by the

Management.

4. In absence of PAN, Bank is deducting TDS on interest at higher

rate than the normal rate of TDS i.e. @ 20%. However, the

Centre has now got the PAN and accordingly from February

onwards normal rate has been applied by Bank for TDS.

5. Previous year’s figures have been regrouped / rearranged

wherever considered necessary.

Accountant Director Chairman

(S.K. Saini) (Dr. K.K. Chopra) (Dr. L.S. Chauhan)

Place: New Delhi

Date : 28.09.2017

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VISIT OF PARLIAMENTARIANS

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VISIT OF NABL ASSESSOR

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VISIT OF HIGHER GOVERNMENT DIGNITARIES

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WORLD TB WEEK CELEBRATION