antibiotic in daily life
TRANSCRIPT
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!"#$%'( %" *+%,- .%/01+"+" 1+2-+34+"005 146*
!"#7%'8&$%+,
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The first antibiotic in the world
Penicillin
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9+'308%+, N0,,
- protect the cell
- genetic material
- cell movement- contains organelles
- controls permeability
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- Skin infection- Pus ,wound
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K8+7 1&(%#E0 9+'%,,%
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- Tetanus
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- Gas gangrene
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- Gonorrhea
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!"#$%' !'#E%3-
Bacteriostatic- just inhibits or
slows down of
bacterial growth
- Host immunity willbe able to get rid
of the bacteria then
Bacteriacidal- Kill the bacteria
Depends on spectrum of Activity
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Depends on spectrum of Activity
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1. Narrow spectrum : Active to few species of bacteria
(some Gram positive cocci / or
some Gram negative bacilli)
2. Intermediate spectrum
: Active to several species of bacteria
both Gram positive and Gram negative ,
but not to other microbial
3. Broad spectrum : Active to several species of bacteria and
also other microbial including virus, fungi
and parasite
Depends on spectrum of Activity
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LJP 10"%'%,,%"
Without cell wall, bacteria are no longo live
Bactericidal
Bacterial cell lysis
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Beta-lactam groupPenicillin CephalosporinMonobactamCarbapenem
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Common use in penicillin group Amoxicillin+clavulanic
Ampicillin Cloxacillin Penicillin
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Allergy :Rash:Nausea:Diarrhea:Shock
Common possible side effects
- Person with allergic status should avoid this group of drug
- Penicillin is so allergenic !!
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Bactericidal
Bacterial cell lysis
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Bacteriostatic
Bacterial growth stops!!
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T6 18&30%" M-"340(%( S"4%$%3&8(
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Bacteriostatic
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Bacteriostatic
Bacterial growth stops!!
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