ariadne ats 1:00am 0.05 mg n.e

1
159 Ariadne 12/~4/68 ATS 1:00AM 0.05 mg N.E. 12/6/68 Robert PM 0.10 mg N.Effect. 12/8/68 ATS 12noon 0.20 mg - PM [with] a little wine & grass - amnesia to 6AM. no effect? 2/20/69 ATS 9:45AM 2.5 mg - almost believable mood elevation - no sensory. 13Mar/69 Robert 4PM 2.9 mg - seemed definite mood - nothing perceptual - antidepressant sans jitters of speed. ATS 4.0 mg Nothing: or 1 hr of busy enthusiasm evening - extremely tranquil - grasses at Claremont Hotel. 17/Mar/69 Robert 4:30PM 4.5 mg Worked [with] enthusiasm - cleared up 4 year inventory of procrastination! ATS ~10:30 6.0 mg Manic all day - definitely anti-depress wild at Dow. May 13 1969 Robert 5.0 mg Going with efficiency into third day - the schizo on remission incident. Very effective. Mouse toxicity: March 7, 1969 25mg/Kg i.p. 11:58AM [0:02] slow, awkward gait [0:12] move when prodded - some tremors [0:27] occasional "hiccup" spasm - moves about but oddly [3:00] all OK 50mg/Kg 1:55PM [0:12] spastic shivering [1:15] tremors. survived. 100mg/Kg i.p. 11:45AM. [0:03] not moving much. [0:05] tremors - unsteady gait. [0:08] - convulsions - death. June-July 1970 G.W. notes - Page 192 -193 . Blind studies

Upload: others

Post on 01-Feb-2022

1 views

Category:

Documents


0 download

TRANSCRIPT

159Ariadne

12/~4/68 ATS 1:00AM 0.05 mg N.E. 12/6/68 Robert PM 0.10 mg N.Effect.

12/8/68 ATS 12noon 0.20 mg - PM [with] a little wine & grass - amnesia to 6AM. no effect?

2/20/69 ATS 9:45AM 2.5 mg - almost believable mood elevation - no sensory.

13Mar/69 Robert 4PM 2.9 mg - seemed definite mood - nothing�� perceptual - antidepressant sans jitters of speed.

ATS 4.0 mg Nothing: or 1 hr of busy enthusiasm evening - extremely tranquil - grasses at Claremont Hotel.

17/Mar/69 Robert 4:30PM 4.5 mg Worked [with] enthusiasm - cleared up 4 year inventory of procrastination!

ATS ~10:30 6.0 mg Manic all day - definitely anti-depress wild at Dow.

May 13 1969 Robert 5.0 mg Going with efficiency into third day - the schizo on remission incident. Very effective.

Mouse toxicity: March 7, 1969

25mg/Kg i.p. 11:58AM [0:02] slow, awkward gait [0:12] move when prodded - some tremors [0:27] occasional "hiccup" spasm - moves about but oddly [3:00] all OK

50mg/Kg 1:55PM [0:12] spastic shivering [1:15] tremors. survived.

100mg/Kg i.p. 11:45AM. [0:03] not moving much. [0:05] tremors - unsteady gait. [0:08] - convulsions - death.

June-July 1970 G.W. notes - Page 192-193.

Blind studies