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  • 8/6/2019 Artifacts and Misadventures in Digital Radiography

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    www.appliedradiology.com APPLIED RADIOLOGY s 11January 2004

    C

    onsidering the sales hyperbole

    associated with digital radiogra-

    phy (DR), one may wonder if itis even possible to produce a non-

    diagnostic digital image. Certainly DR

    is more tolerant of inappropriate expo-

    sure factor selection than is conventional

    film-screen radiology. However, classic

    technical errors (such as malpositioning,

    patient motion, incorrect patient identifi-

    cation, incorrect examination, and dou-

    ble exposure) still occur in the usual

    frequency.1 The unfortunate truth is that

    DR is subject to many of the same inac-

    curacies as conventional radiography, inaddition to many new ones that are a

    direct result of the way the DR image is

    generated. An understanding of the

    causes of both new and old problems is

    necessary in order to avoid these inaccu-

    racies and recover unacceptable images.

    Artifacts and digital systemsAn artifact is a feature in an image that

    masks or mimics a clinical feature. The liter-

    ature classifies artifacts according to

    causative agent, such as hardware, software,

    or operator,2-5 although artifacts can also be

    categorized by the mechanism of interfer-

    ence with image acquisition, processing, or

    display.6 Misadventures encompasses the

    entire gamut of technical errors that can pro-

    duce unsatisfactory images.

    The reports cited above concentrated

    on computed radiography (CR), that is,

    any imaging system that relies on photo-

    stimulable luminescence to make a radi-

    ographic image. In contrast, this article

    also provides examples of problems that

    may be encountered with any DR system,

    including direct digital radiography

    (DDR) systems that make digital radi-

    ographs from the photoelectric interac-

    tion of X-rays with the detector itself,

    indirect digital radiography (IDR) sys-

    tems that are sensitive to the light pro-

    duced by an intensification screen, and

    optically coupled direct radiography

    (OCDR) systems that use optical compo-

    nents to focus fluorescence onto charge

    coupled detectors (CCD). In this context,

    DR includes any radiographic image

    acquired without photographic film, thus

    excluding film digitizers whose artifacts

    are described elsewhere.

    DR systemsDigital radiographs in this study were

    produced with a variety of devices in

    clinical service at our institutions or avail-

    Artifacts and misadventures

    in digital radiography

    Cha rles E. Willis, PhD, DABR; Ste phen K. Tho mpson, MS, DABR; S. Jeff She pard, MS, DABR

    Dr. Willis is an Associate Professor inthe Department of Radiology, BaylorCollege of Medicine, Houston, TX. Mr.Thompson is a Medical Physicist withMemorial Medical Center, Modesto,CA.Mr. Shepardis a Senior MedicalPhysicist in the Department of Diagnos-tic Physics, University of Texas M.D.Anderson Cancer Center, Houston, TX.

    This article is based on material origi-nally presented in: Willis CE. Artifactsand misadventures in digital radiogra-phy. Presented at the Society of Com-puter Applications in Radiology Meeting.

    SCAR University Course 305, 20th Sym-posium. Boston, MA, June 710, 2003.

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    able to us, including Agfa CR (Agfa

    Medical Systems, Ridgefield Park, NJ),

    Fuji CR (Fujifilm Medical Systems,

    Stamford, CT), GE DR (GE Medical

    Systems, Milwaukee, WI), and Canon

    DR (Canon USA, Inc., Lake Success,

    NY). Although not shown, we have simi-

    lar experiences with Kodak CR (Eastman

    Kodak, Rochester, NY), Lumisys CR

    (now owned by Eastman Kodak), Konica

    CR (Konica Medical Imaging, Inc.,

    Wayne, NJ), and Hologic DR (Hologic,

    Inc., Bedford, MA).

    Acquiring good quality imagesRegardless of the acquisition technology,

    good radiographic images can be produced

    only when certain fundamental require-

    ments are met. Appropriate radiographic

    technique must be used, which includes the

    proper tube potential (kVp), beam current

    (mAs), source-to-image distance (SID),

    collimation, alignment of the X-ray central

    ray, and positioning of detector and subject

    for the specific anatomic projection.

    The detector must receive enough

    X-rays to make a good image.7 Whether

    from underexposure or misalignment of a

    scatter reduction grid, too few X-rays

    produce noisy images (Figures 1 and 2).

    Too many X-rays are a disservice to the

    patient and may also produce poor

    images (Figure 3). Although DR is more

    tolerant of incorrect exposure factor

    selection, it cannot make up for extra

    noise, loss in subject contrast, and signal

    out of its range of adjustment.

    Exposure factor creep is a well-

    known phenomenon related to the wide

    exposure latitude of DR.8,9Observers tend

    to complain about noise in DR imagesexposed at one-fourth to one-half of the

    appropriate level. On the other hand, arti-

    facts are generally not apparent until the

    exposure exceeds 10 times the appropriate

    level. Technologists soon learn to avoid

    the unpleasant circumstance of repeating

    an underexposed study by routinely

    increasing the radiographic technique.

    Thus, the potential for gross overexposure

    exists in DR. Image optical density (OD),

    the usual indicator of proper exposure, is

    arbitrary in DR. Managment of exposurefactor in DR must rely on the value of a

    derived exposure indicator, which itself is

    subject to interference. However, pro-

    grams that monitor the exposure indicator

    have been shown to be effective in con-

    trolling exposure factor in DR.10

    System installation and maintenanceIn order to make good images, the DR

    device must be properly calibrated, con-

    figured, maintained, and operated. Every

    individual DR device must be calibrated

    for overall gain and uniformity.11 This is

    usually performed during the initial

    installation and should be repeated peri-

    odically. Acquisition devices should be

    calibrated for gain or sensitivity, and to

    compensate for nonuniformity (Figures

    4 and 5). Display devices should be cali-

    brated to provide output according to the

    DICOM Part 14 Grayscale Display

    Function, including hard-copy devices,

    12 s APPLIED RADIOLOGY www.appliedradiology.com January 2004

    FIGURE 1. (A and B) Underexposed computed radiography (CR) images demonstrate increase in quan-

    tum mottle and loss of contrast in dense features. These constitute approximately 9% of all rejected images.

    These images were acquired on an Agfa CR System (Agfa Medical Systems, Ridgefield Park, NJ).

    FIGURE 2. (A) Underexposed direct digital radiography (DR) at 125 kVp and 4.4 mAs caused

    an exposure data recognition failure. (B) Repeated exposure at 7 mAs. These images were

    acquired on a GE DR system (GE Medical Systems, Milwaukee, WI).

    A B

    A B

    DR ARTIFACTS AND MISADVENTURES

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    A B

    www.appliedradiology.com APPLIED RADIOLOGY s 13January 2004

    DR ARTIFACTS AND MISADVENTURES

    FIGURE 3. (A) Overexposed computed radiography (CR) images demonstrate loss of contrast in skin and dense features. These constitute approxi-

    mately 5% of all rejects. (B) Repeated exposure. These images were acquired on an Agfa CR System (Agfa Medical Systems, Ridgefield Park, NJ).

    FIGURE 4. (A) Improper calibration of a computed radiography (CR) system causes loss of contrast in dense features. (B) Exposure repeated

    after calibration for nonuniformity and sensitivity. These images were acquired on a Fuji CR System (Fujifilm Medical Systems, Stamford, CT).

    A B

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    soft-copy devices, and displays used for quality control (QC).12

    Processing algorithms used by the DR system must be

    designed to anticipate the use of this display function in order

    to properly render the image for display. Not all vendors

    adhere to this standard. Calibrated, high-quality QC monitors

    are essential on every acquisition system and QC workstation.

    Adjusting image processing on an uncalibrated monitor leads

    to unsatisfactory images.

    During the initial installation, it is important to make sure

    that the DR system is properly configured with the most up-to-

    date version of software, hardware, and durable goods. Multi-

    ple vintages of imaging plates exist for CR, and some are not

    universally compatible with CR hardware. The software and

    settings should be consistent with the versions and settings in

    operation with other individual DR systems at the site, includ-

    ing examination-specific parameter settings (Figure 6). All DR

    systems have an internally calculated estimate of exposure. The

    DR system may need to be configured to report this value to the

    digital image management system, and the image management

    system may need to be configured to display it to the radiolo-

    gist. When CR is introduced into an imaging operation, photo-

    timers in all X-ray rooms need to be recalibrated to deliver the

    appropriate exposure.13 The methodology for phototimer cali-

    bration is different because DR density is adjustable.

    Scheduled and unscheduled service should be done in a thor-

    ough and timely manner, including reporting and documenting,

    cleaning, and repairs. Operator functions include cleaning, report-

    ing service interruptions, removing the unit from clinical service,

    re-introducing the unit into clinical service, and documenting

    service events (Figure 7). Service engineer functions include

    14 s APPLIED RADIOLOGY www.appliedradiology.com January 2004

    FIGURE 5. Improper calibration of digital radiography (DR). Note

    interfaces of four detectors visible at arrows. This image was acquired

    on a Canon DR system (Canon USA, Inc., Lake Success, NY).

    FIGURE 6. (A) Computed radiography (CR) corduroy artifact (arrows) is an

    interference pattern generated from the interaction of the line rate of a fixed

    scatter reduction grid, the sampling rate of the detector, and display zoom fac-

    tor and pixel dimensions. This image was taken on an Agfa CR system (Agfa

    Medical Systems, Ridgefield Park, NJ). (B) These CR cassettes are marked

    to indicate orientation when inserted into the CR scanner. Each orientation

    was appropriate only for a specific scanner model. Inserting in the incorrect ori-

    entation caused jams. (C) CR image displayed according to exam-specific

    processing parameters in the main department. (D) Same image displayed

    according to settings in orthopedic department. Images B, C and D were

    acquired on a Fuji CR System (Fujifilm Medical Systems, Stamford, CT) .

    A

    B

    C

    DR ARTIFACTS AND MISADVENTURES

    D

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    www.appliedradiology.com APPLIED RADIOLOGY s 15January 2004

    DR ARTIFACTS AND MISADVENTURES

    performing scheduled maintenance that

    includes preventive maintenance and soft-

    ware and hardware upgrades, as well as

    unscheduled maintenance or repairs. On-site support for DR requires a team with

    expertise not only in image acquisition, but

    in picture archiving and communications

    systems (PACS), radiology information

    systems (RIS), technologist workflow,

    image quality, and networks, as well.

    Training and system operationDigital radiography systems must be

    operated properly to produce good

    images. Technologists are often unfamil-

    iar with DR features and functions, and

    may require additional training beyond

    vendor applications training. Technolo-gists need to select the proper examina-

    tion; in addition, they must properly

    associate demographic and examination

    information to the image, properly

    manipulate the detector, and review the

    image before releasing it to the image

    management system. Beyond this, tech-

    nologists need to know how to recover

    from errors without repeating examina-

    tions and need to follow exposure factor

    control limits. Quality control processes

    must be in place to detect and correct

    unsatisfactory images (Figures 8, 9, and

    10). Digital radiography requires a new

    approach to QC and study reject analy-sis.14 Electronic images can disappear

    without a trace: counting the films

    remaining in the film bin is no longer a

    useful method for determining the num-

    ber of repeated images.

    Double exposure is a classic operator

    error that constitutes approximately 2%

    of all rejected images. The consequence

    of double exposure can be either a single

    repeated examination, when an inani-

    mate object is involved (Figure 11), or

    FIGURE 7. Artifacts on clinical images constitute 3% of all rejects. (A) Artifact observed (arrow) after technologist frees jam from computed radiography

    (CR). (B) CR plate discoloration (arrow). (C) CR plate defect in two different orientations (arrows). Images A, B, and C were acquired on an Agfa CR sys-

    tem (Agfa Medical Systems, Ridgefield Park, NJ). (D) Dust on Fuji CR collection optics (arrows) (Fujifilm Medical Systems, Stamford, CT).

    A B

    C D

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    two repeated examinations when two patients are involved

    (Figure 12). In DR, double exposures can also be caused by

    power interruptions and communications errors, as well as by

    inadequate erasure secondary to overexposure or erasuremechanism failure.

    Image processingAppropriate digital image processing is key to producing good

    DR images. All DR systems have extremely wide latitude, which

    means that connected to a display system with a relatively narrow

    dynamic range, DR images have extremely low contrast. The pri-

    mary purpose of image processing is to maximize the contrast of the

    part of the image that contains relevant clinical details.15,16 To do this,

    the DR system locates either the boundary of collimation or the bor-

    der of the projected anatomy, and disregards details outside this

    16 s APPLIED RADIOLOGY www.appliedradiology.com January 2004

    FIGURE 8. (A) Artifact on computed radiography (CR) image

    (arrows) released by technologist and reported by the radiologist.

    (B) Same artifact (arrows) reported later on another image from the

    same machine by the same radiologist. Images were acquired on an

    Agfa CR system (Agfa Medical Systems, Ridgefield Park, NJ).

    FIGURE 9. It is difficult to distinguish debris on this computed radiogra-

    phy (CR) imaging plate from foreign bodies (arrows). The technologist

    must open the cassette and inspect the plate or re-expose the cas-

    sette. These errors constitute

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    www.appliedradiology.com APPLIED RADIOLOGY s 17January 2004

    DR ARTIFACTS AND MISADVENTURES

    FIGURE 10. (A and B) Missing lines or pixels in computed radiography (CR) can indicate memory problems, digitization problems, or communi-

    cation errors. Images were acquired on an Agfa CR system (Agfa Medical Systems, Ridgefield Park, NJ).

    FIGURE 11. Double exposures with computed radiography (CR) requiring a single repeat study. (A) Backboard or gurney side rails. (B) Cas-

    sette left in buckey tray during fluoroscopy. Images were acquired on an Agfa CR system (Agfa Medical Systems, Ridgefield Park, NJ).

    AB

    A B

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    18 s APPLIED RADIOLOGY www.appliedradiology.com January 2004

    FIGURE 12. (A and B) Double exposures with computed radiography (CR) requiring two repeats.

    Images were acquired on an Agfa CR system (Agfa Medical Systems, Ridgefield Park, NJ).

    FIGURE 13. Exposure Data Recognizer (EDR)

    failure, an inability of the software to determine

    collimation boundaries. This type of failure can

    be caused when the operator fails to follow colli-

    mation rules or when interferences prevent the

    software from detecting the collimation bound-

    aries. It results in incorrect histogram analysis

    and inappropriate rescaling. Image acquired on

    the Fuji computed radiography system (Fujifilm

    Medical Systems, Stamford, CT).

    FIGURE 14. (A) Error in computed radiography (CR) automatic detection of the collimation field. (B) Manually collimated images. Images were

    acquired on an Agfa CR system (Agfa Medical Systems, Ridgefield Park, NJ).

    FIGURE 15. (A) Inappropriate processing

    of pediatric digital radiography image by

    vendor-supplied parameters suitable for

    adults. (B) Image processed by parameters

    modified by the customer. Images acquired

    on GE DR system (GE Medical Systems,

    Milwaukee, WI).

    A B

    A B

    A B

    DR ARTIFACTS AND MISADVENTURES

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    www.appliedradiology.com APPLIED RADIOLOGY s 19January 2004

    DR ARTIFACTS AND MISADVENTURES

    boundary. Errors in collimation can causemistakes in detection of the boundary, with

    a dramatic loss of image contrast (Figures

    13 and 14).

    The secondary function of image pro-

    cessing is to customize contrast in the

    region of interest (Table 1). This type of

    image processing includes modifying the

    image to enhance the contrast and sharp-

    ness of some features while compromis-

    ing the contrast and sharpness of others, as

    well as modifying the image to make it

    appear more like a conventional transillu-minated film. This secondary image pro-

    cessing is applied in a manner that is

    usually specific to the anatomic projec-

    tion. Errors in the selection of the

    anatomic projection can cause inappropri-

    ate processing (Figure 15).

    An auxiliary purpose of image process-

    ing is to improve the usability of the digital

    image.17 This includes imprinting demo-

    graphic overlays, adding annotations,

    applying borders and shadow masks, flip-

    ping and rotating, increasing magnifica-tion, conjoining images for special

    examinations like scoliosis, and modifying

    the sequence of views. This processing

    may require a separate QC workstation.

    Image processing is not a panacea.

    Misuses of image processing include

    compensating for inappropriate radi-

    ographic technique, compensating for

    poor calibration of acquisition and dis-

    play devices, and surreptitious deletion of

    nondiagnostic images. Image processing

    to recover nondiagnostic images to pre-vent re-exposure should be a last resort,

    not a routine activity. Routine reprocess-

    ing indicates a problem with automatic

    image processing or technical practice.

    Access to image-processing software is

    essential to develop and maintain appro-

    priate processing parameters.

    Automatic image processing involves

    assumptions about the radiographic tech-

    nique, the composition of anatomic

    region imaged, and the use of collima-

    tion. A number of factors can interferewith the automatic detection of the

    boundaries of the radiation field, includ-

    ing nonparallel collimation, use of multi-

    ple fields on a single imaging plate, poor

    centering, implants (especially when they

    overlie the boundary), and violation of

    collimation rules provided by the vendor.

    For example, placement of gonadal

    shields is no longer trivial, but may

    adversely affect image quality.

    ConclusionsA multitude of factors affect DR

    image quality, and no device or operator

    is immune to unacceptable images. A

    strategy for addressing images that just

    didnt turn out right must be imple-

    mented. Responsibilities for document-

    ing, reporting, and taking corrective

    action must be clearly established.

    Wider dynamic range means that tech-

    nologists have to pay attention to expo-

    sure indicator values, instead of bright-ness and contrast. Without this attention,

    patient dose will escalate. If exposure

    indicator logs are available, they need to

    be evaluated. If they arent, this will

    need to be done manually. Vendors need

    to make such logs available in conve-

    nient digital form. New technologies

    should be developed for dealing with

    pediatric examinations and patients with

    prosthetic devices. New image process-

    ing strategies may be needed with these

    special patients, as well.Thorough training and active onsite

    support of the technical staff are crucial.

    For many, this is a completely different

    way of thinking about the imaging

    process. Technologists are generally

    eager to become involved and master this

    new technology, but they need proper

    training and guidance to use it effectively

    to produce diagnostic-quality images.

    REFERENCES1. Willis CE, Mercier J, Patel M. Modification of con-

    ventional quality assurance procedures to accommo-date computed radiography. Presented at the 13th

    Conference on Computer Applications in Radiology.

    Denver, Colorado. June 7, 1996: 275-281.

    2. Oestmann JW, Prokop M, Schaefer CM, Galanski

    M. Hardware and software artifacts in storage phos-

    phor radiography. RadioGraphics.1991;11:795-805.

    3. Solomon SL, Jost RG, Glazer HS, et al. Artifacts in

    computed radiography. AJR: Am J Roentgenol.

    1991;157:181-185.

    4. Volpe JP, Storto ML, Andriole KP, Famsu G. Arti-

    facts in chest radiography with a third generation

    computed radiography system. AJR: Am J

    Roentgenol.1996;166:653-657.

    5. Tucker DM, Souto M, Barnes GT. Scatter in com-

    Table 1. Secondary image processing methods in CR

    Process names by vendor*

    Processing method Fuji Agfa Kodak

    Remapping grayscales Gradation processing Sensitometry Look-up-table (LUT)Edge enhancement Frequency processing Edge contrast Unsharp mask

    Noise reduction

    Decomposition and modification Multi-objective frequency Musicaprocessing

    Adjustment of tone scale for Dynamic range control Latitude reduction Enhanced visualizationlimited display processing (EVP)

    Correction of streaks in Tomographic artifactlinear tomography suppression (TAS)

    Dual energy imaging Energy subtraction

    *Fuji CR (Fujifilm Medical Systems, Stamford, CT); Agfa CR (Agfa Medical Systems, Ridgefield Park, NJ); Kodak CR (Eastman Kodak, Rochester, NY).These items are different methods, but have equivalent purposes.

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    8. Freedman M, Pe E, Mun SK, et al. The potential for

    unnecessary patient exposure from the use of storagephosphor imaging systems. SPIE. 1993;1897:472-479.

    9. Gur D, Fuhman CR, Feist JH, et al. Natural migra-

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    12. Thompson SK, Willis CE, Krugh KT, et al. Imple-

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    16. Huda W, Slone RM, Arreola M, et al. Significance

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    DR ARTIFACTS AND MISADVENTURES

    Submitted articles may include reviews that present background on a particular clinical situation and

    detail the relevant imaging techniques and radiologic findings. Or, a review article may address a partic-

    ular modality or technologic application and discuss appropriate clinical applications for this technique.

    In addition to these clinical review articles, articles may pertain to radiology administration, fiscal,

    technical assessment, and medico-legal topics.

    Currently, the journal is particularly seeking articles in the following areas: nuclear medicine, geni-tourinary imaging, ultrasound, gastrointestinal imaging, pediatric imaging, and PACS and radiology

    technology applications.

    Articles should be submitted to: Stuart E. Mirvis, MD, FACR

    Editor-in-Chief, Applied Radiology

    Diagnostic Imaging Department

    University of Maryland Medical Center

    22 South Greene Street

    Baltimore, MD 21201-1595

    [email protected]

    All materials submitted toApplied Radiology must be original work, and may not have been published

    elsewhere. Articles should be written for the needs of practicing radiologists and should reflect practical

    clinical applications, rather than research activity.

    All articles are reviewed for presentation, content, and whether or not they are appropriate for the journal.

    The corresponding author will be notified of the review determination promptly.

    Complete author guidelines for submission of manuscripts are available at AR Online:

    www.appliedradiology.com.Call

    forPap

    ers

    invites article submissions for review andconsideration for publication.