attachment u-2 screening values and toxicity … · cpec (mg/kg) (mg/kg) inorganic compounds barium...

ATTACHMENT U-2

SCREENING VALUES AND TOXICITY REFERENCE VALUES

TABLES

Table U.A2-1.Summary of Soil Screening Values for Ecological Communities

Terrestrial Plant Soil Invertebrate

Screening Valuesa Screening Valueb

CPEC (mg/kg) (mg/kg)

Inorganic Compounds

Barium 500 330 c

Beryllium 10 40 c

Cadmium 32 c 140 c

Chromium 1.0 0.4

Cobalt 13 c 50 m

Copper 70 c 80 c

Cyanide (Total) - 0.9 f

Cyanide (Amenable) - 0.9 f

Lead 120 c 1700 c

Manganese 220 c 450 c

Mercury 0.3 0.1

Molybdenum 2 40 m

Nickel 38 c 280 c

Selenium 1.0 70

Thallium 1.0 1.0 f

Tin 50 50 m

Vanadium 2.0 1.59 l

Zinc 50 100 b

Volatile Organic Compounds (VOCs)

1,1,1 - Trichloroethane - 5 h

1,1 - Dichloroethylene 100 k 5 h

1,1-Dichloroethane - 5 h

1,2 - Dichloroethene - 5 h

Acetone - -

Acetonitrile - -

Acrolein - -

Benzene - 0.5 m

Carbon disulfide - -

Diisopropyl ether - -

Ethylbenzene - 5.0 m

Freon 113 (1,1,2-trichloro-1,2,2-trifluoroethane) - -

Isopropanol 10 k -

Methylcyclopentane - -

Methyl ethyl ketone - -

- -

Methylene chloride - 2.0 f

Propanal - -

Tert-Butyl alcohol (TBA) - -

Tetrachloroethylene 100 k 0.2 h

Tetrahydrofuran - 4.0 m

Toluene 200 3.0 m

Trichloroethylene - 0.01 h

Methyl isobutyl ketone

January 2011Att 2 Tables_Final RIR_Jan 2011_121610.xls 1 of 4 Final Remedial Investigation Report





Semi Volatile Organic Compounds (SVOCs)

Benzoic acid - -

Bis(2-ethylhexyl)phthalate 200 r 200 g

Diethylphthalate 100 200 g

Di-n-butylphthalate 200 200 g

N-Nitrosodimethylamine - 20 j

N-Nitrosodipropylamine - 20 j

N-Nitrosomethylethylamine - 20 j

N-Nitrosopyrrolidine - -

Organochlorine Pesticides

4,4’-DDD 0.9 n 0.1 n

4,4’-DDE 0.9 n 0.1 n

4,4’-DDT 0.9 k 0.1 o

Aldrin 1.0 k, t 0.5 o, t

BHC (technical HCH) 10 k 0.03 k

Chlordane 0.224 l 0.043 o

Dieldrin 1.0 k 0.5 o

Endosulfan I 10 k 0.05 o

Endosulfan II 10 k 0.05 o

Endosulfan sulfate 10 k 0.05 o, p

Endrin - 0.0095 o

Heptachlor 1.0 d 0.007 o

Heptachlor epoxide 1.0 d,s 0.007 o,s

Hexachlorobenzene 100 k 2.0 h

Kepone (chlordecone) - -

Methoxychlor - -

Mirex - -

Polychlorinated Biphenyls (PCBs)

Aroclor 1260 40 1.0 m

Total PCB Congeners 40 1.0 m

Total PCB TEQ NA NA

Organophosphate Pesticides/Herbicides

2,4-DB - -

2,4,5-TP (Silvex) - -

2-sec-Butyl-4,6-dinitrophenol (Dinoseb) - -

Dalapon - -

Dichlorprop - -

MCPA - -

MCPP - -

Dioxin/Furans

Total Dioxin/Furan TEQ NA NA

Total Avian TEQ NA NA

Total Mammalian TEQ NA NA






Polycyclic Aromatic Hydrocarbons (PAHs)u

2-Methylnaphthalene 10 i 5.0 m,i

Acenaphthene 20 5.0 m,i

Acenaphthylene 10 i 5.0 m,i

Anthracene 10 i 5.0 m,i

Benzo(a)anthracene 1.2 e 1.0 m,e

Benzo(a)pyrene 1.2 d 1.0 m

Benzo(b)fluoranthene 1.2 e 1.0 m,e

Benzo(g,h,i)perylene 1.2 e 1.0 m,e

Benzo(k)fluoranthene 1.2 e 1.0 m,e

Chrysene 1.2 e 1.0 m,e

Fluoranthene 1.2 e 1.0 m,e

Fluorene 10 i 5.0 m,i

Indeno(1,2,3-c,d)pyrene 1.2 e 1.0 m,e

Naphthalene 10 k 5.0 m

Phenanthrene 10 i 5.0 m

Pyrene 1.2 e 10 m

Total LMW PAH 10 k,i 5 m,i

Total HMW PAH 1.2 d,e 1.0 m,e

mg/kg Milligrams per kilogram.CPEC Chemicals of potential ecological concern.

- Not available.

NA Not applicable.

TEQ Toxicity equivalent.

Total LMW PAHs Total low molecular weight polycyclic aromatic hydrcarbons

Total HMW PAHs Total high molecular weight polycyclic aromatic hydrcarbonsa From Efroymson et al. (1997a) unless otherwise noted.b From Efroymson et al. (1997b) unless otherwise noted.c From USEPA EcoSSL Guidance (USEPA, 2005a). d

Hazardous Waste Combustion Facilities (USEPA, 1999b).e Benzo(a)pyrene values used as surrogate for high molecular weight PAHs.f From USEPA Region 4 Supplemental Guidance to RAGS (USEPA, 2001b).g Dimethylphthalate surrogate used.h From Canadian Environmental Quality Guidelines for residential soil (CCME, 2006).i Napthalene values used as surrogate for low molecular weight PAHs.j N-nitrosodiphenylamine values used as surrogate.k Developed for the ERA as described in Attachment 2.l USEPA Region 5 RCRA ESLs (2003b).

m Beyer, 1990- "B" Values, toxicity data indicate need for further assessment.n DDT used as a surrogate.o Maximum Permissible Concentrations, Crommentuijn (2000a), Van de Plassche (1994).p Endosulfan used as a surrogate.q Derived from toxicity data (Crommentuijn et al. , 1997a).r Di-n-butylphthalate used as a surrogate.s Heptachlor used as a surrogate.t Dieldrin used as a surrogate.

From USEPA Screening Level Ecological Risk Assessment Protocol for






u Screening levels for individual PAHs presented here, however, risks were estimated for

total LMW PAHs and total HMW PAHs based on surrogate screening levels.


Table U.A2-2.Summary of Sediment Screening Values for Ecological Communities

Low Value High Value


Inorganic Compounds

Barium - -

Cadmium 0.99 a 4.98 a

Chromium (Total) 43.4 a 111 a

Copper 31.6 a 149 a

Lead 35.8 a 128 a

Manganese 460 j 1100 j

Mercury 0.18 a 1.06 a

Molybdenum - -

Nickel 22.7 a 48.6 a

Selenium 2.5 k 4 k

Thallium - -

Tin - -

Zinc 121 a 459 a


1,1-Dichloroethane 0.000575 g -

1,2 - Dichloroethene - -

Acetone 0.0099 g 0.057 d

Benzene 0.142 g 1.0 f,i

Carbon disulfide 0.0239 g -

Diisopropyl ether - -

Ethylbenzene 0.175 g 3.0 f,i

Freon 113 (1,1,2-trichloro-1,2,2-trifluoroethane) - -

Methylcyclopentane - -

Methyl ethyl ketone 0 0424 g -

Selected Screening Values for Sediment

Methyl ethyl ketone 0.0424 g -

Methyl isobutyl ketone 0.0251 g -

Methylene chloride 0.159 g 20 f,i

Propanal - -

Tetrahydrofuran - -

Trichloroethylene 0.112 g 13 f,i


4,4’-DDD 0.00488 a 0.028 a

4,4’-DDE 0.00316 a 0.0313 a

4,4’-DDT 0.00416 a 0.0629 a

Chlordane 0.00324 a 0.0176 a

Endosulfan I 0.001 f,i 0.00326 g

Endosulfan II 0.001 f,i 0.00194 g

Endosulfan sulfate 0.001 f,I,e 0.0346 g,e

Endrin 0.00222 a 0.207 a

Heptachlor [c] 0.00247 a 0.016 a

Hexachlorobenzene 0.02 g 0.24 j

Kepone (chlorodecone) 0.00331 g -

CSCJanuary 2011Att 2 Tables_Final RIR_Jan 2011_121610.xls 1 of 3 Final Remedial Investigation Report






Aroclor 1260 0.0598 a 0.676 a

Total PCB Congeners 0.0598 a 0.676 a

Total PCB TEQ NA NA


2,4-DB - -

Dichlorprop 3.2 f,i -

MCPP 0.002 f,i -

Dioxin/Furans

Total Dioxin/Furan TEQ NA NA

Total Avian TEQ NA NA

Total Mammalian TEQ NA NA

Polycyclic Aromatic Hydrocarbons (PAHs)n

2-Methylnaphthalene 0.176 a,b 0.561 a,b

Benzo(a)anthracene 0.108 a 1.05 a

Benzo(a)pyrene 0.15 a 1.45 a

Benzo(b)fluoranthene 10.4 g -

Benzo(g,h,i)perylene 0.17 g 3.2 j

Chrysene 0.166 a 1.29 a

Fluoranthene 0.423 a 2.23 a

Fluorene 0.0774 a 0.536 a

Indeno(1,2,3-c,d)pyrene 0.2 g 3.2 j

Naphthalene 0.176 a 0.561 a

Phenanthrene 0.204 a 1.17 a

a aPyrene 0.195 a 1.52 a

Total LMW PAH 0.176 a,b 0.561 a,b

Total HMW PAH 0.15 a,m 1.45 a,m

CPEC Chemicals of potential ecological concern.

TEC Threshold effects concentration.

PEC Probable effects concentrations.

mg/kg Miligrams per kilogram.

- Not available.

NA Not applicable

TEQ Toxicity equivalent.

Total LMW PAHs Total low molecular weight polycyclic aromatic hydrcarbons

Total HMW PAHs Total high molecular weight polycyclic aromatic hydrcarbonsa From MacDonald (2000) except when noted.b Napthalene used as a surrogate.c Heptachlor epoxide value used as a surrogate.d USEPA Screening Level Ecological Risk Assessment Protocol for

Hazardous Waste Combustion Facilities (USEPA, 1999b)e Endosulfan used as surrogatef Environmental Quality Standards Maximum Permissible Concentrations, Crommentuijn et al. (2000a)g From EPA Region 5 Ecological Screening Levels (USEPA, 2003b).






h From USEPA Region 4 Supplemental Guidance to RAGS (USEPA, 2001b).i Based on EqP.j Guidelines for the Protection and Management of Aquatic Sediment Quality (Persaud, 1993). k From NIWQP (1998)l Low TRV is Lowest Effect Level and High TRV is Severe Effects Level, assuming 1% OC.

m Benzo(a)pyrene used as a surrogate.n Screening levels for individual PAHs presented here, however, risks were estimated for

total LMW PAHs and total HMW PAHs based on surrogate screening levels.


Tab

le U

.A2-

3.S

umm

ary

of S

urfa

ce W

ater

Scr

eeni

ng V

alue

s fo

r E

colo

gica

l Com

mun

itie

s

Sele

cted

Scr

eeni

ng V

alue

s fo

r P

rote

ctio

n of

Aqu

atic

Lif

eA

mph

ibia

n Sc

reen

ing

Val

ues

Low

est C

hron

ic V

alue

s fo

r

Aqu

atic

Pla

nts

in F

resh

wat

erc

NA

WQ

C f

or A

quat

ic L

ife

(acu

te/C

MC

)b

CP

EC

(µg/

L)

(µg/

L)

(µg/

L)

(µg/

L)

Inor

gani

c C

ompo

unds

Ant

imon

y30

c,h

3k

610

-

Ars

enic

150

a,b

0.4

k48

340

Bar

ium

4.0

c2.

3j

15,0

00,0

00s

-

Ber

ylli

um0.

66c

0.03

2k

100,

000

-

Cad

miu

m3

a0.

0158

k2

3.0

q

Chr

omiu

m25

0a

0.3

l39

779

4.2

q

Cob

alt

23c

0.5

k60

e-

Cop

per

13.0

a0.

01j

119

.7q

Lea

d3.

9a,

b0.

4l

500

100.

1q

Man

gane

se12

0c

0.5

j4,

000

e-

Mer

cury

0.77

b0.

01l

51.

4

Mol

ybde

num

370

c0.

4j

500

e-

Nic

kel

73a,

b0.

02j

565

9.8

q

Sele

nium

5.0

a,b

0.9

l10

029

0r

Silv

er0.

36c

0.04

1k

306.

5q

Tha

lliu

m12

c0.

1j

100

-

Tin

73c

002

j10

000

0e

Tin

73c

0.02

j10

0,00

0e

-

Van

adiu

m20

c0.

03j

200

e-

Zin

c17

0a,

b0.

047

k30

165.

2q

Vol

atil

e O

rgan

ic C

ompo

unds

(V

OC

s)

1,1-

Dic

hlor

oeth

ane

47c

0.2

j-

-

1,2-

Dib

rom

oeth

ane

(ED

B)

1400

g-

--

Ace

tone

1500

c19

.8l

122

l-

Ace

toni

tril

e75

.5i,o

116

k-

-

Car

bon

disu

lfid

e0.

92c

1.2

l-

-

Eth

ylen

e gl

ycol

2000

n32

60l

546,

000

l-

Met

hyl i

sobu

tyl k

eton

e (M

IBK

)17

0c

-41

0l

-

CSC

Janu

ary

2011

Att

2 T

able

s_Fi

nal R

IR_J

an 2

011_

1216

10.x

ls1

of 4

Fina

l Rem

edia

l Inv

esti

gati

on R

epor

t

Tab

le U

.A2-

3.S

umm

ary

of S

urfa

ce W

ater

Scr

eeni

ng V

alue

s fo

r E

colo

gica

l Com

mun

itie

s

Sele

cted

Scr

eeni

ng V

alue

s fo

r P

rote

ctio

n of

Aqu

atic

Lif

eA

mph

ibia

n Sc

reen

ing

Val

ues

Low

est C

hron

ic V

alue

s fo

r

Aqu

atic

Pla

nts

in F

resh

wat

erc

NA

WQ

C f

or A

quat

ic L

ife

(acu

te/C

MC

)b

CP

EC

(µg/

L)

(µg/

L)

(µg/

L)

(µg/

L)

Met

hyle

ne c

hlor

ide

2200

c12

2j

--

Non

anal

--

--

Pro

pana

l-

-7,

960

l-

Tri

chlo

roet

hyle

ne36

0g

450

k31

7l

-

Sem

i Vol

atil

e O

rgan

ic C

ompo

unds

(SV

OC

s)

Bis

(2-c

hlor

oeth

yl)

ethe

r61

g-

--

Bis

(2-e

thyl

hexy

l)ph

thal

ate

3.0

c,h

38.8

l32

00l

-

N-N

itro

sodi

ethy

lam

ine

--

--

N-N

itro

sodi

prop

ylam

ine

210

m, c

--

-

N-N

itro

sopy

rrol

idin

e-

--

-

Dio

xin/

Fur

ans

Tot

al A

vian

TE

QN

A-

NA

-

Tot

al M

amm

alia

n T

EQ

NA

-N

A-

Pol

ycyc

lic

Aro

mat

ic H

ydro

carb

ons

(PA

Hs)

t

Ben

zo(a

)ant

hrac

ene

0.02

7c

870

d85

0d

-

Ben

zo(a

)pyr

ene

0.01

4c

870

l85

0l

-B

enzo

(a)p

yren

e0.

014

870

850

Ben

zo(b

)flu

oran

then

e0.

029

g87

0l

850

l-

Ben

zo(g

,h,i)

pery

lene

0.10

g87

0d

850

d-

Dib

enzo

(a,h

)ant

hrac

ene

7.5

g87

0l

850

l-

Nap

htha

lene

12c

21k

33,0

00c

-

Tot

al L

MW

PA

H12

c,f

21k,

f33

,000

c,f

-

Tot

al H

MW

PA

H0.

014

c,d

870

l,d85

0l,d

-

CSC

Janu

ary

2011

Att

2 T

able

s_Fi

nal R

IR_J

an 2

011_

1216

10.x

ls2

of 4

Fina

l Rem

edia

l Inv

esti

gati

on R

epor

t

Tab

le U

.A2-

3.S

umm

ary

of S

urfa

ce W

ater

Scr

eeni

ng V

alue

s fo

r E

colo

gica

l Com

mun

itie

s

Sele

cted

Scr

eeni

ng V

alue

s fo

r P

rote

ctio

n of

Aqu

atic

Lif

eA

mph

ibia

n Sc

reen

ing

Val

ues

Low

est C

hron

ic V

alue

s fo

r

Aqu

atic

Pla

nts

in F

resh

wat

erc

NA

WQ

C f

or A

quat

ic L

ife

(acu

te/C

MC

)b

CP

EC

(µg/

L)

(µg/

L)

(µg/

L)

(µg/

L)

µg/

LM

icro

gram

s pe

r li

ter.

CM

Ccr

iter

ion

max

imum

con

cent

rati

on

CP

EC

Che

mic

als

of p

oten

tial

eco

logi

cal c

once

rn.

LC

10L

etha

l con

cent

rati

on f

or te

n pe

rcen

t of

sam

ple

popu

lati

on.

-N

ot a

vail

able

.

NA

Not

app

lica

ble.

NA

WQ

CN

atio

nal A

mbi

ent W

ater

Qua

lity

Cri

teri

a

TE

QT

oxic

ity

equi

vale

nt.

Tot

al L

MW

PA

Hs

Tot

al lo

w m

olec

ular

wei

ght p

olyc

ycli

c ar

omat

ic h

ydrc

arbo

ns

Tot

al H

MW

PA

Hs

Tot

al h

igh

mol

ecul

ar w

eigh

t pol

ycyc

lic

arom

atic

hyd

rcar

bons

aFr

om U

SEP

A W

ater

Qua

lity

Sta

ndar

ds; E

stab

lish

men

t of

Num

eric

Cri

teri

a fo

r

Pri

orit

y T

oxic

Pol

luta

nts

for

the

Stat

e of

Cal

ifor

nia

(USE

PA

, 200

6b)

unle

ss o

ther

wis

e no

ted.

Val

ues

for

cadm

ium

, chr

omiu

m, c

oppe

r, le

ad, n

icke

l, an

d zi

nc w

ere

adju

sted

usi

ng th

e si

te-

spec

ific

med

ian

hard

ness

val

ue o

f 15

0 m

g/L

(C

VR

WQ

CB

, 200

7).

bFr

om U

SEP

A N

atio

nal R

ecom

men

ded

Wat

er Q

uali

ty C

rite

ria

(USE

PA

, 200

6c).

Val

ues

for

cadm

ium

, chr

omiu

m, c

oppe

r, le

ad, n

icke

l, an

d zi

nc w

ere

adju

sted

usi

ng th

e si

te-

spec

ific

med

ian

hard

ness

val

ue o

f 15

0 m

g/L

(C

VR

WQ

CB

, 200

7).

cFr

om S

uter

and

Tsa

o (1

996)

.(

)d

Ben

zo(a

)pyr

ene

used

as

a su

rrog

ate.

eFr

om E

froy

mso

n et

al.

(199

7a).

fN

apth

alen

e us

ed a

s a

surr

ogat

e.g

From

Fre

shw

ater

Aqu

atic

Hab

itat

Goa

ls (

SFR

WQ

CB

, 200

5)h

From

Rec

omm

ende

d N

umer

ical

Lim

its

to T

rans

late

Wat

er Q

uali

ty O

bjec

tive

s (C

VR

WQ

CB

, 200

7).

iU

SEP

A R

egio

n 4

Supp

lem

ent t

o R

AG

S; C

hron

ic S

cree

ning

Val

ues

for

Fres

h W

ater

(U

SEP

A, 2

001b

).jL

C10

val

ue f

rom

Spa

rlin

g et

. al.

(200

0)/ U

F of

10.

kL

C50

val

ue f

rom

Pau

li e

t al.

(200

0) /

UF

of 1

00.

lD

eriv

ed f

rom

EC

OT

OX

dat

a as

des

crib

ed in

Att

ache

men

t 2.

mN

-nit

roso

diph

enyl

amin

e us

ed a

s a

surr

ogat

e.n

Wat

er M

anag

emen

t Pol

icie

s G

uide

line

s P

rovi

ncia

l Wat

er Q

uali

ty O

bjec

tive

s (M

OE

E, 1

999)

.

CSC

Janu

ary

2011

Att

2 T

able

s_Fi

nal R

IR_J

an 2

011_

1216

10.x

ls3

of 4

Fina

l Rem

edia

l Inv

esti

gati

on R

epor

t

Tab

le U

.A2-

3.S

umm

ary

of S

urfa

ce W

ater

Scr

eeni

ng V

alue

s fo

r E

colo

gica

l Com

mun

itie

s

Sele

cted

Scr

eeni

ng V

alue

s fo

r P

rote

ctio

n of

Aqu

atic

Lif

eA

mph

ibia

n Sc

reen

ing

Val

ues

Low

est C

hron

ic V

alue

s fo

r

Aqu

atic

Pla

nts

in F

resh

wat

erc

NA

WQ

C f

or A

quat

ic L

ife

(acu

te/C

MC

)b

CP

EC

(µg/

L)

(µg/

L)

(µg/

L)

(µg/

L)

pA

cryl

onit

rile

use

d as

a s

urro

gate

.q

CM

C e

xpre

ssed

as

a fu

ncti

on o

f ha

rdne

ss (

mg/

L)

in th

e w

ater

col

umn.

Val

ue c

orre

spon

ds to

a s

ite-

spec

ific

med

ian

hard

ness

of

150

mg/

L. C

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Table U.A2-4.Summary of Toxicity Reference Values for Wildlife

CPEC Low TRV Species Endpoint High TRV Species Endpoint Low TRV Sources (primary) High TRV

Inorganic Compounds

Antimony 0.059 Rat (Rattus norvegicus ) REP Rossi et al, 1987; USEPA, 2007 a 0.59 Rat (Rattus norvegicus ) REP Rossi et al, 1987; USEPA, 2007 a, g - - - -

Arsenic 1.04 Dog (Canis familiaris ) GRONeiger and Osweiler, 1989; USEPA, 2007 a 1.66 Rat (Rattus norvegicus ) GRO Neiger and Osweiler, 1989; USEPA, 2007 a, g 0.32 Schroeder & others 1968 4.7 Brown & others 1976

Barium 51.8 - REP, GRO Geomean; USEPA, 2007 a 121 - REP, GRO Geomean; USEPA, 2007 a, g - - - -

Beryllium 0.530 Rat (Rattus norvegicus ) MORSchroeder and Mitchener, 1975; USEPA, 2007 a 0.630 Rat (Rattus norvegicus ) GRO Schroeder and Mitchener, 1975; USEPA, 2007 a, g - - - -

Cadmium 0.77 Rat (Rattus norvegicus ) GRO Yuhas et al, 1979; USEPA, 2007 a 7.7 Rat (Rattus norvegicus ) GRO Yuhas et al, 1979; USEPA, 2007 a, g 0.06 Webster 1988 2.64 Schroeder & Mitchener 1971

Chromium 2.4 - REP, GRO Geomean; USEPA, 2007 a 9.62 - REP, GRO Geomean; USEPA, 2007 a, g - - - -

Cobalt 7.33 - REP, GRO Geomean; USEPA, 2007 a 19.3 - REP, GRO Geomean; USEPA, 2007 a, g 1.20 Domingo & others 1985 20 Mollenhauer & others 1985

Copper 5.6 Pig (Sus scrofa ) GRO, MOR Allcroft et al, 1961; USEPA, 2007 a 9.34 Pig (Sus scrofa) GRO, MOR Allcroft et al, 1961; USEPA, 2007 a, g 2.67 Pocino & others 1991 632 Hebert & others 1993

Cyanide (Total) 4.5 Rat (Rattus norvegicu s) REP NTP, 1993 g 12.5 Rat (Rattus norvegicus ) REP NTP, 1993 g - - - -

Sources Sources (primary; secondary) Sources (primary)CSC Proposed Mammal TRVsg

Toxicity Reference Values for Mammals (mg/kg-day) c

BTAG Mammal TRVsh, z

Lead 4.7 Rat (Rattus norvegicus ) GRO Kimmel et al., 1980; USEPA, 2007 a 8.90 Rat (Rattus norvegicus ) GRO Kimmel et al., 1980; USEPA, 2007 a, g 1.00 Wise 1981 241 Krasovskii & others 1979

Manganese 51.5 - REP, GRO Geomean; USEPA, 2007 a 146 - REP, GRO Geomean; USEPA, 2007 a, g 13.70 Gray & Laskey 1980 159 Gray & Laskey 1980

Mercury 0.25 - -EPA – Great Lakes, Khera and Tabacova 1973; CalEPA, 2002b z 4 - -

EPA – Great Lakes, Fuyuta & others 1978; CalEPA, 2002 z 0.25

EPA – Great Lakes, Khera and Tabacova 1973 4

EPA – Great Lakes, Fuyuta & others 1978

Molybdenum 0.26 Mouse (Mus musculus ) REPSchroeder and Mitchener, 1971; Sample et al, 1996 b 2.6 Mouse (Mus musculus ) REP Schroeder and Mitchener, 1971; Sample et al, 1996 b - - - -

Nickel 1.7 Mouse (Mus musculus ) REPPandey and Srivastava, 2000; USEPA, 2007 a 3.4 Mouse (Mus musculus ) REP Pandey and Srivastava, 2000; USEPA, 2007 a, g 0.13 Smith & others 1993 31.6 Smith & others 1993

Selenium 0.05 - - Harr & others, 1967; CalEPA, 2002 z 1.21 - - Schroeder & Mitchener, 1971; CalEPA, 2002 z 0.05 Harr & others, 1967 1.21 Schroeder & Mitchener, 1971

Silver 6.02 Pig (Sus scrofa ) GRO Van Vleet, 1976; USEPA, 2007 a 60.2 Pig (Sus scrofa) GRO Van Vleet, 1976; USEPA, 2007 a, g - - - -

Thallium 0.48 - - Downs & others 1960; CalEPA, 2002 z 1.43 - - Downs & others 1960; CalEPA, 2002 z 0.48 Downs & others 1960 1.43 Downs & others 1960

Tin 25.30 Mouse (Mus musculus ) REP Davis & others 1987; Sample et al, 1996 i 37.8 Mouse (Mus musculus ) REP Davis & others 1987; Sample et al, 1996 i - - - -

Vanadium 4.16 Mouse (Mus musculus ) REP, GRO, MOR Sanchez et al, 1991; USEPA, 2007 a 8.31 Mouse (Mus musculus ) REP, GRO, MOR Sanchez et al, 1991; USEPA, 2007 a, g - - - -

Zinc 9.61 - - Aughey & others 1977; CalEPA, 2002 z 411.43 - - Shlicker & Cox 1968; CalEPA, 2002 z 9.61 Aughey & others 1977 411.43 Shlicker & Cox 1968


1,1,1 - Trichloroethane 1000 Mouse (Mus musculus ) REP Lane et al. 1982; Sample et al, 1996 b 3550 Mouse (Mus musculus ) REP NTP, 2000 g - - - -

1,1 - Dichloroethene 30 Rat (Rattus norvegicus) MOR Quast et al. 1983; Sample et al, 1996 b 300 - - - t - - - -

1,1-Dichloroethane 475 Mouse (Mus musculus ) MOR Klaunig et al. 1986 g 4750 - - - t - - - -

1,2 - Dichloroethene 45.2 Mouse (Mus musculus ) GRO Palmer et al. 1979; Sample et al, 1996 b 452 - - - t - - - -

1,2-Dibromoethane (EDB) 2.7 Rat (Rattus norvegicus) REP NCI, 1978 g 27 Rat (Rattus norvegicus ) REP NCI, 1978 g - - - -

1,2,3-Trichlorobenzene 19 Dog (Canis familiaris ) Hepatic degeneration Monsanto, 1967; Knapp, 1971 g,w 38 Dog (Canis familiaris ) Hepatic degeneration Monsanto, 1967; Knapp, 1971 g,w - - - -

1,2-Dichlorobenzene 19 Dog (Canis familiaris ) Hepatic degeneration Monsanto, 1967; Knapp, 1971 g,w 38 Dog (Canis familiaris ) Hepatic degeneration Monsanto, 1967; Knapp, 1971 g,w - - - -

1,2-Dichloroethane 50 Mouse (Mus musculus ) REP Lane et al. 1982; Sample et al, 1996 b 500 - - - t - - - -

1,2-Dichloropropane 30 Rat (Rattus norvegicus ) REP Kirk et al, 1989 g 125 Rat (Rattus norvegicus ) REP Kirk et al (1989) g - - - -

1,3-Dichlorobenzene 19 Rat (Rattus norvegicus ) Hepatic degeneration Monsanto, 1967; Knapp, 1971 g,w 38 Dog (Canis familiaris ) Hepatic degeneration Monsanto, 1967; Knapp, 1971 g,w - - - -

1,4-Dichlorobenzene 19 Dog (Canis familiaris ) Hepatic degeneration Monsanto, 1967; Knapp, 1971 g,w 38 Dog (Canis familiaris ) Hepatic degeneration Monsanto, 1967; Knapp, 1971 g,w - - - -

3,3,5-Trimethylcyclohexanone - - - - - - - - - - - -

Acetone 10 Rat (Rattus norvegicus )Liver and kidney

damage EPA 1986; Sample et al, 1996 50 Rat (Rattus norvegicus ) Liver and kidney damage EPA 1986; Sample et al, 1996 b - - - -

A t it il 0 46 R t (R tt i )Lesions and other

ff t Q t t l 1980 USEPA 1999 d, u 4 6 R t (R tt i )Lesions and other organ

ff t Q t t l 1980 USEPA 1999b d, uAcetonitrile 0.46 Rat (Rattus norvegicus ) organ effects Quast et al., 1980; USEPA, 1999 d, u 4.6 Rat (Rattus norvegicus ) effects Quast et al., 1980; USEPA, 1999b d, u - - - -

Acrolein 0.05 Rat (Rattus norvegicus ) MOR Parent et al., 1992 g 0.5 Rat (Rattus norvegicus ) MOR Parent et al., 1992 g - - - -

Benzene 26.36 Mouse (Mus musculus ) REPNawrot and Staples 1979; Sample et al, 1996 b 263.6 Mouse (Mus musculus ) REP Nawrot and Staples 1979; Sample et al, 1996 b - - - -

Carbon disulfide 11Rabbit (Oryctolagus cuniculus ) REP Hardin et al. 1981 g 25 Rabbit (Oryctolagus cuniculus REP Jones-Price et al. 1984 g - - - -

Chlorobenzene 19 Dog (Canis familiaris ) Hepatic degeneration Monsanto, 1967; Knapp, 1971 g 38 Dog (Canis familiaris ) Hepatic degeneration Monsanto, 1967; Knapp, 1971 g - - - -

Chloroform 15 Rat (Rattus norvegicus )Liver/kidney/gonad

condition Palmer et al. 1979; Sample et al, 1996 b 41 Rat (Rattus norvegicus ) REP Palmer et al. 1979; Sample et al, 1996 b - - - -



CPEC

Inorganic Compounds

Antimony

Arsenic

Barium

Beryllium

Cadmium

Chromium

Cobalt

Copper

Cyanide (Total)

Low TRV Species Endpoint High TRV Species Endpoint Low TRV Sources (primary) High TRV Sources (primary)

- - - - - - - - - - - - -

2.24 Chicken (Gallus domesticus ) REP, GRO, MORHolcman and Stibilj, 1997; USEPA, 2007 a 3.60 Chicken (Gallus domesticus ) GRO Howell and Hill, 1978; USEPA, 2007 a 5.5 Stanley, Jr. & others 1994 22 Stanley, Jr. & others 1994

20.8 Chicken (Gallus domesticus ) MOR Johnson et al. 1960; Sample et al, 1996 b 41.7 Chicken (Gallus domesticus ) MOR Johnson et al. 1960; Sample et al, 1996 b - - - -

- - - - - - - - - - - -

1.47 - REP, GRO Geomean; USEPA, 2007 a 5.88 - REP, GRO Geomean; USEPA, 2007 a 0.08 Cain & others 1983 10.4 Richardson & others 1974

2.66 - REP, GRO Geomean; USEPA, 2007 a 2.78 - REP, GRO Geomean; USEPA, 2007 a - - - -

7.61 - REP, GRO Geomean; USEPA, 2007 a 11.5 - REP, GRO Geomean; USEPA, 2007 a - - - -

4.05 Chicken (Gallus domesticus ) REP Ankari et al, 1998; USEPA, 2007 a 12.1 Chicken (Gallus domesticus ) REP Ankari et al, 1998; USEPA, 2007 a 2.3 Norvell & others 1975 52.3 Jensen & Maurice 1978

0.04 American kestrel (Falco sparveriu s) MOR Wiemeyer et al., 1986; USEPA, 1999 d 0.4American kestrel (Falco sparveriu s) MOR Wiemeyer et al., 1986; USEPA, 1999 d - - - -

Sources (primary; secondary)Sources (primary; secondary)CSC Proposed Bird TRVsg Bird BTAG TRVsh, z

Toxicity Reference Values for Birds (mg/kg-day)c

Lead

Manganese

Mercury

Molybdenum

Nickel

Selenium

Silver

Thallium

Tin

Vanadium

Zinc


1.63 Chicken (Gallus domesticus ) REP Edens and Garlich, 1983; USEPA, 2007 a 3.3 Chicken (Gallus domesticus ) REP Edens and Garlich, 1983; USEPA, 2007 a 0.014Edens & others 1976, Edens & Garlich 1983 8.75 Edens & Garlich 1983

179 - REP, GRO Geomean; USEPA, 2007 a 377 - REP, GRO Geomean; USEPA, 2007 a 77.6 Laskey & Edens 1985 776 Laskey & Edens 1985

0.039 - -EPA – Great Lakes, Heinz 1974, 1975, 1976, 1979; CalEPA, 2002 z 0.18 - -

EPA – Great Lakes, Heinz & Locke 1976; CalEPA, 2002 z 0.039

EPA – Great Lakes, Heinz 1974, 1975, 1976, 1979 0.18

EPA – Great Lakes, Heinz & Locke 1976

3.5 Chicken (Gallus domesticus ) REPLepore and Miller 1965; Sample et al, 1996 b 35.3 Chicken (Gallus domesticus ) REP Lepore and Miller 1965; Sample et al, 1996 b - - - -

6.71 - REP, GRO Geomean; USEPA, 2007 a 21.0 - REP, GRO Geomean; USEPA, 2007 a 1.38 Cain & Pafford 1981 56.3 Cain & Pafford 1981

0.23 - - Heinz & others, 1989; CalEPA, 2002 z 0.93 - - Heinz & others, 1989; CalEPA, 2002 z 0.23 Heinz & others, 1989 0.93 Heinz & others, 1989

2.02 Turkey (Meleagris gallopavo ) GRO Jensen et al, 1974; USEPA, 2007 a 20.2 Turkey (Meleagris gallopavo ) GRO Jensen et al, 1974; USEPA, 2007 a - - - -

0.35 European starling (Sturnus vulgaris ) MOR Schafer, 1972; USEPA, 1999 d 3.5European starling (Sturnus vulgaris ) MOR Schafer, 1972; USEPA, 1999 d - - - -

6.8 Japanese quail (Coturnix japonica ) REPSchlatterer & others 1993; Sample et al, 1996 i, z 16.9

Japanese quail (Coturnix japonica ) REP

Schlatterer & others 1993; Sample et al, 1996 i, b - - - -

0.344 Chicken (Gallus domesticus ) GRO Hill, 1979; USEPA, 2007 a 0.7 Chicken (Gallus domesticus ) GRO Hill, 1979; USEPA, 2007 a - - - -

17.2 - - Gasaway & Buss 1972; CalEPA, 2002 z 172 - - Gasaway & Buss 1972; CalEPA, 2002 z 17.2 Gasaway & Buss 1972 172 Gasaway & Buss 1972

1,1,1 - Trichloroethane

1,1 - Dichloroethene

1,1-Dichloroethane

1,2 - Dichloroethene

1,2-Dibromoethane (EDB)

1,2,3-Trichlorobenzene

1,2-Dichlorobenzene

1,2-Dichloroethane

1,2-Dichloropropane

1,3-Dichlorobenzene

1,4-Dichlorobenzene

3,3,5-Trimethylcyclohexanone

Acetone

A t it il

17.2 Chicken (Gallus domesticus ) REP Alumot at al. 1976; Sample et al, 1996 n, b 34.4 Chicken (Gallus domesticus ) REP Alumot at al. 1976; Sample et al, 1996 n, b - - - -

- - - - - - - - - - - -

17.2 Chicken (Gallus domesticus ) REP Alumot at al. 1976; Sample et al, 1996 n, b 34.4 Chicken (Gallus domesticus ) REP Alumot at al. 1976; Sample et al, 1996 n, b - - - -

- - - - - - - - - - - -

- - - - - - - - - - - -

NA - - - NA - - - - - - -

NA - - - NA - - - - - - -

17.2 Chicken (Gallus domesticus ) REP Alumot at al. 1976; Sample et al, 1996 n, b 34.4 Chicken (Gallus domesticus ) REP Alumot at al. 1976; Sample et al, 1996 b - - - -

NA - - - NA - - - - - - -

NA - - - NA - - - - - - -

NA - - - NA - - - - - - -

NA - - - NA - - - - - - -

52 Quail (Callipepla spp ) -Hill and Camardese, 1986; USEPA, 1999 d 5,200 Quail (Callipepla spp ) - Hill and Camardese, 1986; USEPA, 1999 d - - - -

Acetonitrile

Acrolein

Benzene

Carbon disulfide

Chlorobenzene

Chloroform

- - - - - - - - - - - -

- - - - - - - - - - - -

- - - - - - - - - - - -

- - - - - - - - - - - -

NA - - - NA - - - - - - -

NA - - - NA - - - - - - -



CPEC Low TRV Species Endpoint High TRV Species Endpoint Low TRV Sources (primary) High TRVSources Sources (primary; secondary) Sources (primary)CSC Proposed Mammal TRVsg



Diethyl ether 165 Rat (Rattus norvegicus ) Renal degeneration Chun et al. 1992 g, x 1240 Rat (Rattus norvegicus ) Re-l degeneration Chun et al. 1992 g,x - - - -

Diisopropyl ether 165 Rat (Rattus norvegicus ) Renal degeneration Chun et al. 1992 g, x 1240 Rat (Rattus norvegicus ) Re-l degeneration Chun et al. 1992 g, x - - - -

Ethylbenzene 29.1 Rat (Rattus norvegicus )Re-l and hepatic

degeneration Wolf et al., 1956 g 291 Rat (Rattus norvegicus ) Re-l and hepatic degeneration Wolf et al. in 1956 g - - - -

Ethylene glycol 100 Rat (Rattus norvegicus ) MOR Blood et al. 1965 g 250 Rat (Rattus norvegicus ) MOR Blood et al. 1965 g - - - -

Freon 113 (1,1,2-trichloro-1,2,2-trifluoroethane) - - - - - - - - - - - -

Isopropanol 125 Rat (Rattus norvegicus )Hypoactivity and

ataxia USEPA, 1986 g,j 500 Rat (Rattus norvegicus ) Hypoactivity and ataxia USEPA, 1986 g,j - - - -

Methylcyclopentane - - - - - - - - - - - -

Methyl ethyl ketone 1771 Rat (Rattus norvegicus ) REP Cox et al. 1975; Sample et al, 1996 b 4571 Rat (Rattus norvegicus ) REP Cox et al. 1975; Sample et al, 1996 b - - - -

Li d kid

Microbiological Associates 1986 (obtained from Health Effects Assessment S T bl (HEAST EPA 1993f)

Methyl isobutyl ketone 25 Rat (Rattus norvegicus )Liver and kidney

functionSummary Tables (HEAST; EPA 1993f); Sample et al, 1996 b 250 - - - t - - - -

Methylene chloride 5.85 Rat (Rattus norvegicus ) Liver histology NCA 1982; Sample et al, 1996 b 50 Rat (Rattus norvegicus ) Liver histology NCA 1982; Sample et al, 1996 b - - - -

Nonanal - - - - - - - - - - - -

o-Xylene 2.1 Mouse (Mus musculus ) REP Marks et al. 1982; Sample et al, 1996 b 2.6 Mouse (Mus musculus ) REP Marks et al. 1982; Sample et al, 1996 b - - - -

Propanal - - - - - - - - - - - -

Tert-Butyl alcohol (TBA) 125 Rat (Rattus norvegicus )Hypoactivity and

ataxia USEPA, 1986 g,j 500 Rat (Rattus norvegicus ) Hypoactivity and ataxia USEPA, 1986 g,j - - - -

Tetrachloroethylene 1.4 Mouse (Mus musculus ) HepatotoxicityBuben and O'Flaherty 1985; Sample et al, 1996 b 7 Mouse (Mus musculus ) Hepatotoxicity Buben and O'Flaherty 1985; Sample et al, 1996 b - - - -

Tetrahydrofuran 300 Rat (Rattus norvegicus ) REP Hellwig et al. 2002 g 700 Rat (Rattus norvegicus ) REP Hellwig et al. 2002 g - - - -

Toluene 26 Mouse (Mus musculus ) REPNawrot and Staples 1979; Sample et al, 1996 b 260 Mouse (Mus musculus ) REP Nawrot and Staples 1979; Sample et al, 1996 b - - - -

Total Xylenes 2.1 Mouse (Mus musculus ) REP Marks et al. 1982; Sample et al, 1996 b 2.6 Mouse (Mus musculus ) REP Marks et al. 1982; Sample et al, 1996 b - - - -

Trichloroethylene 0.7 Mouse (Mus musculus ) HepatotoxicityBuben and O'Flaherty 1985; Sample et al, 1996 b 7 Mouse (Mus musculus ) Hepatotoxicity Buben and O'Flaherty 1985; Sample et al, 1996 b - - - -

Vinyl chloride 0.17 Rat (Rattus norvegicus ) MOR Feron et al. 1981; Sample et al, 1996 b 1.7 Rat (Rattus norvegicus ) MOR Feron et al. 1981; Sample et al, 1996 b - - - -


B i id 500 R t (R tt i )Decreased body

i ht M dt 1960 g 750 R t (R tt i ) D d b d i ht M dt 1960 gBenzoic acid 500 Rat (Rattus norvegicus ) weights Marquardt 1960 g 750 Rat (Rattus norvegicus ) Decreased body weights Marquardt 1960 g - - - -

Bis(2-chloroethyl) ether 2.5 Rat (Rattus norvegicus )Decreased body

weights Weisburger et al, 1981 g 25 Rat (Rattus norvegicus ) Decreased body weights Weisburger et al, 1981 g - - - -

Bis(2-ethylhexyl)phthalate 18.3 Rat (Rattus norvegicus ) REP Lamb et al. 1987; Sample et al, 1996 b 183 Mouse (Mus musculus ) REP Lamb et al. 1987; Sample et al, 1996 b - - - -

Diethylphthalate 1910 Rat (Rattus norvegicus ) Teratogenic effects Field et al., 1993 g 3210 Rat (Rattus norvegicus ) Teratogenic effects Field et al., 1993 g - - - -

Di-n-butylphthalate 550 Mouse (Mus musculus ) REP Lamb et al. 1987; Sample et al, 1996 b 1833 Mouse (Mus musculus ) REP Lamb et al. 1987; Sample et al, 1996 b - - - -

N-Nitrosodiethylamine 0.002 Mouse (Mus musculus ) REP Anderson et al., 1978 g,l 0.02 Mouse (Mus musculus ) REP Anderson et al., 1978 g,l - - - -

N-Nitrosodimethylamine 0.002 Mouse (Mus musculus ) REP Anderson et al., 1978 g 0.02 Mouse (Mus musculus ) REP Anderson et al., 1978 g - - - -

N-Nitrosodipropylamine 0.002 Mouse (Mus musculus ) REP Anderson et al., 1978 g,l 0.02 Mouse (Mus musculus ) REP Anderson et al., 1978 g,l - - - -

N-Nitrosomethylethylamine 0.002 Mouse (Mus musculus ) REP Anderson et al., 1978 g,l 0.02 Mouse (Mus musculus ) REP Anderson et al., 1978 g,l - - - -

N-Nitrosopyrrolidine - - - - - - - - - - - -


4,4’-DDD 0.147 Rat (Rattus norvegicus ) REP Wrenn et al., 1970; USEPA, 2005a 0.735 Rat (Rattus norvegicus ) REP Wrenn et al., 1970; USEPA, 2007 a, g 0.8EPA – Great Lakes, Fitzhugh 1948 16

EPA – Great Lakes, Clement and Oakley 1974

4,4’-DDE 0.147 Rat (Rattus norvegicus ) REP Wrenn et al., 1970; USEPA, 2005a 0.735 Rat (Rattus norvegicus ) REP Wrenn et al., 1970; USEPA, 2007 a, g 0.8EPA – Great Lakes, Fitzhugh 1948 16

EPA – Great Lakes, Clement and Oakley 1974

EPA – Great Lakes, Fitzhugh EPA – Great Lakes, Clement and 4,4’-DDT 0.147 Rat (Rattus norvegicus ) REP Wrenn et al., 1970; USEPA, 2005a 0.735 Rat (Rattus norvegicus ) REP Wrenn et al., 1970; USEPA, 2007 a, g 0.8

, g1948 16

,Oakley 1974

Aldrin 0.1 - - Paul & others 1992; CalEPA, 2002b 1 - - Paul & others 1992; CalEPA, 2002 z 0.1 Paul & others 1992 1 Paul & others 1992

BHC (technical HCH) 0.05 - -Naishtein and Leibovich 1971; CalEPA, 2002b ,s 3.75 - - Sirczr & Lahiri 1989; CalEPA, 2002b s 0.05 Naishtein and Leibovich 1971 3.75 Sirczr & Lahiri 1989



CPEC

Diethyl ether

Diisopropyl ether

Ethylbenzene

Ethylene glycol

Freon 113 (1,1,2-trichloro-1,2,2-trifluoroethane)

Isopropanol

Methylcyclopentane

Methyl ethyl ketone

Low TRV Species Endpoint High TRV Species Endpoint Low TRV Sources (primary) High TRV Sources (primary)Sources (primary; secondary)Sources (primary; secondary)CSC Proposed Bird TRVsg Bird BTAG TRVsh, z


NA - - - NA - - - - - - -

- - - - - - - - - - - -

- - - - - - - - - - - -

- - - - - - - - - - - -

- - - - - - - - - - - -

- - - - - - - - - - - -

- - - - - - - - - - - -

- - - - - - - - - - - -

Methyl isobutyl ketone

Methylene chloride

Nonanal

o-Xylene

Propanal

Tert-Butyl alcohol (TBA)

Tetrachloroethylene

Tetrahydrofuran

Toluene

Total Xylenes

Trichloroethylene

Vinyl chloride


B i id

- - - - - - - - - - - -

- - - - - - - - - - - -

- - - - - - - - - - - -

NA - - - NA - - - - - - -

- - - - - - - - - - - -

- - - - - - - - - - - -

- - - - - - - - - - - -

- - - - - - - - - - - -

- - - - - - - - - - - -

NA - - - NA - - - - - - -

- - - - - - - - - - - -

NA - - - NA - - - - - - -

Benzoic acid

Bis(2-chloroethyl) ether

Bis(2-ethylhexyl)phthalate

Diethylphthalate

Di-n-butylphthalate

N-Nitrosodiethylamine

N-Nitrosodimethylamine

N-Nitrosodipropylamine

N-Nitrosomethylethylamine

N-Nitrosopyrrolidine


4,4’-DDD

4,4’-DDE

- - - - - - - - - - - -

- - - - - - - - - - - -

1.1 Ringed dove (Streptopelia risoria ) REP Peakall 1974; Sample et al, 1996 b 11.1Ringed dove (Streptopelia risoria ) t - - - -

0.11 Ringed dove (Streptopelia risoria ) REP Peakall 1974; Sample et al, 1996 m,b 1.1Ringed dove (Streptopelia risoria ) REP Peakall 1974; Sample et al, 1996 m, b - - - -

0.11 Ringed dove (Streptopelia risoria ) REP Peakall 1974; Sample et al, 1996 b 1.1Ringed dove (Streptopelia risoria ) REP Peakall 1974; Sample et al, 1996 b - - - -

- - - - - - - - - - - -

- - - - - - - - - - - -

- - - - - - - - - - - -

- - - - - - - - - - - -

- - - - - - - - - - - -

0.227 Chicken (Gallus domesticus ) GRO Cecil et al., 1978; USEPA, 2007 a 2.27 Chicken (Gallus domesticus ) GRO Cecil et al., 1978; USEPA, 2007 a 0.009EPA – Great Lakes, Anderson et al. 1975 1.5 EPA – Great Lakes, Heath et al. 1969

0.227 Chicken (Gallus domesticus ) GRO Cecil et al., 1978; USEPA, 2007 a 2.27 Chicken (Gallus domesticus ) GRO Cecil et al., 1978; USEPA, 2007 a 0.009EPA – Great Lakes, Anderson et al. 1975 0.6 EPA – Great Lakes, Heath et al. 1969EPA – Great Lakes, Anderson

4,4’-DDT

Aldrin

BHC (technical HCH)

0.227 Chicken (Gallus domesticus ) GRO Cecil et al., 1978; USEPA, 2007 a 2.27 Chicken (Gallus domesticus ) GRO Cecil et al., 1978; USEPA, 2007 a 0.009,

et al. 1975 1.5 EPA – Great Lakes, Heath et al. 1969

0.027 Japanese quail (Coturnix japonica ) MOR Hill et al., 1975 g 0.27Japanese quail (Coturnix japonica ) MOR Hil et al., 1975 g - - - -

2 Mallard duck (Anas platyrhynchos ) REP

Chakravarty and Lahiri 1986; Chakravarty et al. 1986; Sample et al, 1996 b 20

Mallard duck (Anas platyrhynchos ) REP

Chakravarty and Lahiri 1986; Chakravarty et al. 1986; Sample et al, 1996 s, b - - - -



CPEC Low TRV Species Endpoint High TRV Species Endpoint Low TRV Sources (primary) High TRVSources Sources (primary; secondary) Sources (primary)CSC Proposed Mammal TRVsg



Chlordane 4.6 Mouse (Mus musculus ) REP

WHO 1984 (secondary source; Primary citation: Keplinger, M.L., W.B. Deichman, and F. Sala. 1968. Effects of pesticides on reproduction in mice. Ind. Med. Surg. 37: 525.); Sample et al, 1996 9.2 Mouse (Mus musculus ) REP

WHO 1984 (secondary source; Primary citation: Keplinger, M.L., W.B. Deichman, and F. Sala. 1968. Effects of pesticides on reproduction in mice. Ind. Med. Surg. 37: 525.); Sample et al, 1996 b - - - -

Dieldrin 0.02 Rat (Rattus norvegicus ) REPTreon and Cleveland 1955; Sample et al, 1996 0.2 Rat (Rattus norvegicus ) REP Treon and Cleveland 1955; Sample et al, 1996 b - - - -

Endosulfan I 0.15 Rat (Rattus norvegicus ) REP Dikshith et al. 1984; Sample et al, 1996 k 1.5 - - - t - - - -

Endosulfan II 0.15 Rat (Rattus norvegicus ) REP Dikshith et al. 1984; Sample et al, 1996 k 1.5 - - - t - - - -

Endosulfan sulfate 0.15 Rat (Rattus norvegicus ) REP Dikshith et al. 1984; Sample et al, 1996 k 1.5 - - - t - - - -

Endrin 0.092 Mouse (Mus musculus ) REP Good and Ware 1969; Sample et al, 1996 0.92 Mouse (Mus musculus ) REP Good and Ware 1969; Sample et al, 1996 b - - - -

Heptachlor 0.13 - - Shain & others 1977; CalEPA, 2002b 6.8 - - Norotsky & others 1995; CalEPA, 2002 z 0.13 Shain & others 1977 6.8 Norotsky & others 1995

Heptachlor epoxide 0.13 - - Shain & others 1977; CalEPA, 2002b ,y 6.8 - - Norotsky & others 1995; CalEPA, 2002b y - - - -

Hexachlorobenzene 0.15 Rat (Rattus norvegicus ) REP Arnold et al. 1985 g 1.5 Rat (Rattus norvegicus ) REP Arnold et al. 1985 g - - - -

Kepone (chlordecone) 0.08 Rat (Rattus norvegicus ) GRO, MOR Larson et al. 1979; Sample et al, 1996 0.4 Rat (Rattus norvegicus ) GRO, MOR Larson et al. 1979; Sample et al, 1996 b - - - -

Methoxychlor 2.5 - - Gray & others 1989; CalEPA, 2002b 50 - - Gray & others 1989; CalEPA, 2002 z 2.5 Gray & others 1989 50 Gray & others 1989

Mirex 0.007 Rat (Rattus norvegicus )Histological changes

in liver/thyroid Chu et al, 1981a g 0.07 Rat (Rattus norvegicus )Histological changes in

liver/thyroid Chu et al, 1981a g - - - -


Aroclor 1260 0.36 - -Simmons and McKee 1992; CalEPA, 2002b 1.28 - - Linzey 1987; CalEPA, 2002 z 0.36 Simmons and McKee 1992 1.28 Linzey 1987

Total PCB Congeners 0.36 - -Simmons and McKee 1992; CalEPA, 2002b 1.28 - - Linzey 1987; CalEPA, 2002 z 0.36 Simmons and McKee 1992 1.28 Linzey 1987

Total Avian PCB TEQ NA - - - NA - - - - - - -

Total Mammalian PCB TEQ 0.000001 Rat (Rattus norvegicus ) REP Murray et al. 1979; Sample et al, 1996 v 0.00001 Rat (Rattus norvegicus ) REP Murray et al. 1979; Sample et al, 1996 v - - - -


2,4-D 8 Dog (Canis familiaris ) MOR Rhodia, Inc., 1969 g, p 25 Dog (Canis familiaris ) MOR Rhodia, Inc., 1969 g, p - - - -

2,4-DB 8 Dog (Canis familiaris ) MOR Rhodia, Inc., 1969 g 25 Dog (Canis familiaris ) MOR Rhodia, Inc., 1969 g - - - -

2,4,5-T 1 Rat (Rattus norvegicus ) REP Smith et al, 1981 g 10 Rat (Rattus norvegicus ) REP Smith et al, 1981 g - - - -

2,4,5-TP (Silvex) 25 Rat (Rattus norvegicus ) REP NAS, 1977 g 50 Rat (Rattus norvegicus ) REP NAS, 1977 g - - - -

2-sec-Butyl-4,6-dinitrophenol (Dinoseb) 0.1 Rat (Rattus norvegicus ) REP Dow Chemical, 1981 g 1 Rat (Rattus norvegicus ) REP Dow Chemical, 1981 g - - - -

Dalapon 8.45 Rat (Rattus norvegicus )Changes in kidney

weight Paynter, 1960 g 28.2 Rat (Rattus norvegicus ) Changes in kidney weight Paynter, 1960 g - - - -

Dichlorprop 8 Dog (Canis familiaris ) MOR Rhodia, Inc., 1969 g,p 25 Dog (Canis familiaris ) MOR Rhodia, Inc., 1969 g,p - - - -

MCPA 0.15 Dog (Canis familiaris )Histopathological

changes in kidney/liverIndustry Task Force on MCPA Research, 1986b g 0.75 Dog (Canis familiaris )

Histopathological changes in kidney/liver Industry Task Force on MCPA Research, 1986b g - - - -

MCPP 3 Rat (Rattus norvegicus )Increased kidney

weight BASF, 1985 g 9 Rat (Rattus norvegicus ) Increased kidney weight BASF, 1985 g - - - -

Dioxin/Furans

Total Avian Dioxin TEQ NA - - - NA - - - - - - -

Total Mammalian Dioxin TEQ 0.000001 Rat (Rattus norvegicus ) REP Murray et al. 1979; Sample et al, 1996 v 0.00001 Rat (Rattus norvegicus ) REP Murray et al. 1979; Sample et al, 1996 v, b - - - -

Polycyclic Aromatic Hydrocarbons (PAHs)

LMW PAHs 50 - - Navarro & others 1991; CalEPA, 2002b f 150 - - Navarro & others 1991; CalEPA, 2002 f, z - - - -

HMW PAHs 1.31 - - Neal & Rigdon 1967; CalEPA, 2002b e 32.8 - - Rigdon & Neal 1969 e - - - -



CPEC

Chlordane

Dieldrin

Endosulfan I

Endosulfan II

Endosulfan sulfate

Endrin

Low TRV Species Endpoint High TRV Species Endpoint Low TRV Sources (primary) High TRV Sources (primary)Sources (primary; secondary)Sources (primary; secondary)CSC Proposed Bird TRVsg Bird BTAG TRVsh, z


2.1Red-winged Blackbird (Agelaius phoeniceus ) MOR Stickel et al. 1983; Sample et al, 1996 b 10.7

Red-winged Blackbird (Agelaius phoeniceus ) MOR Stickel et al. 1983; Sample et al, 1996 b - - - -

0.077 Barn owl (Tyto alba ) REPMendenhall et al. 1983; Sample et al, 1996 b 0.77 Barn owl (Tyto alba ) REP Mendenhall et al. 1983; Sample et al, 1996 b - - - -

10 Gray Partridge (Perdix perdix ) REP Abiola 1992; Sample et al, 1996 b 100 Gray Partridge (Perdix perdix ) REP Abiola 1992; Sample et al, 1996 b - - - -

10 Gray Partridge (Perdix perdix ) REP Abiola 1992; Sample et al, 1996 b 100 Gray Partridge (Perdix perdix ) REP Abiola 1992; Sample et al, 1996 b - - - -

10 Gray Partridge (Perdix perdix ) REP Abiola 1992; Sample et al, 1996 k, b 100 Gray Partridge (Perdix perdix ) REP Abiola 1992; Sample et al, 1996 k, b - - - -

0.01 Screech owl (Otus asio ) REP Fleming et al. 1982; Sample et al, 1996 b 0.1 Screech owl (Otus asio ) REP Fleming et al. 1982; Sample et al, 1996 b - - - -

Heptachlor

Heptachlor epoxide

Hexachlorobenzene

Kepone (chlordecone)

Methoxychlor

Mirex


Aroclor 1260

Total PCB Congeners

Total Avian PCB TEQ

Total Mammalian PCB TEQ

0.65 Quail (Callipepla spp ) MORHill and Camardese, 1986; USEPA, 1999 d 6.5 Quail (Callipepla spp ) MOR Hill and Camardese, 1986; USEPA, 1999 d - - - -

0.65 Quail (Callipepla spp ) MORHill and Camardese, 1986; USEPA, 1999 d, y 6.5 Quail (Callipepla spp ) MOR Hill and Camardese, 1986; USEPA, 1999 d, y - - - -

0.225 Quail (Callipepla spp ) MORHill and Camardese, 1986; USEPA, 1999 d 22.5 Quail (Callipepla spp ) MOR Hill and Camardese, 1986; USEPA, 1999 d - - - -

1.56 Japanese quail (Coturnix japonica ) REP Eroschenko and Place, 1977 g 15.6Japanese quail (Coturnix japonica ) REP Eroschenko and Place, 1977 g - - - -

3.2 Mallard duck (Anas platyrhynchos ) MOR USEPA, 2000 g 32Mallard duck (Anas platyrhynchos ) MOR USEPA, 2000 g - - - -

0.2Common Grackle (Quiscalus quiscula ) MOR Stickel et al., 1973 g 2.0

Common Grackle (Quiscalus quiscula ) MOR Stickel et al., 1973 g - - - -

0.09 - -Platonow & Reinhart 1973; CalEPA, 2002 z 1.27 - - Britton and Huston 1973; CalEPA, 2002 z 0.09

Platonow & Reinhart 1973; CalEPA, 2002b 1.27

Britton and Huston 1973; CalEPA, 2002b

0.09 - -Platonow & Reinhart 1973; CalEPA, 2002 z 1.27 - - Britton and Huston 1973; CalEPA, 2002 z 0.09

Platonow & Reinhart 1973; CalEPA, 2002b 1.27

Britton and Huston 1973; CalEPA, 2002b

0.0000140Ring-necked Pheasant (Phasianus colchicus ) REP Nosek et al. 1992; Sample et al, 1996 v, b 0.0001400

Ring-necked Pheasant (Phasianus colchicus ) REP Nosek et al. 1992; Sample et al, 1996 v, b - - - -

NA - - - NA - - - - - - -


2,4-D

2,4-DB

2,4,5-T

2,4,5-TP (Silvex)

2-sec-Butyl-4,6-dinitrophenol (Dinoseb)

Dalapon

Dichlorprop

MCPA

MCPP

Dioxin/Furans

NA - - - - - - - - - - -

1.2Northern bobwhite (Colinus virginianus ) MOR USEPA, 2000 g 12

Northern bobwhite (Colinus virginianus ) MOR USEPA, 2000 g - - - -

NA - - - NA - - - - - - -

2.4Northern bobwhite (Colinus virginianus ) MOR Hill et al., 1975 g 23.6

Northern bobwhite (Colinus virginianus ) MOR Hill et al., 1975 g - - - -

0.32 Japanese quail (Coturnix japonica ) MOR Hill et al., 1975 g 3.2Japanese quail (Coturnix japonica ) MOR Hill et al., 1975 g - - - -

285 Mallard duck (Anas platyrhynchos ) MOR USFWS, 1975 g 2850Mallard duck (Anas platyrhynchos ) MOR USFWS, 1975 t - - - -

1.2Northern bobwhite (Colinus virginianus ) MOR USEPA, 2000 g,p 12

Northern bobwhite (Colinus virginianus ) MOR USEPA, 2000 g,p - - - -

1.14 Mallard duck (A-s platyrhynchos ) MOR USEPA, 2000 g 11.4Mallard duck (Anas platyrhynchos ) MOR USEPA, 2000 g - - - -

1.14 Mallard duck (Anas platyrhynchos ) MOR USEPA, 2000 g,o 11.4Mallard duck (Anas platyrhynchos ) MOR USEPA, 2000 g,o - - - -

Ri k d Ph t (Ph i Ri k d Ph tTotal Avian Dioxin TEQ

Total Mammalian Dioxin TEQ

Polycyclic Aromatic Hydrocarbons (PAHs)

LMW PAHs

HMW PAHs

0.0000140Ring-necked Pheasant (Phasianus colchicus ) REP Nosek et al. 1992; Sample et al, 1996 b 0.0001400

Ring-necked Pheasant (Phasianus colchicus ) REP Nosek et al. 1992; Sample et al, 1996 b - - - -

NA - - - NA - - - - - - -

( g g

22.8 Mallard duck (Anas platyrhynchos ) Organ weight Patton and Dieter, 1980 f 228Mallard duck (Anas platyrhynchos ) Organ weight Patton and Dieter, 1980 f - - - -

10.0 European starling (Sturnus vulgaris ) Decreased body mass Trust et al., 1994 e 100European starling (Sturnus vulgaris )

Decreased body mass Trust et al., 1994 e - - - -


Tab

le U

.A2-

4.S

umm

ary

of T

oxic

ity

Ref

eren

ce V

alue

s fo

r W

ildlif

e

mg/

kg-d

ayM

illi

gram

s pe

r ki

logr

am p

er d

ay.

BE

RA

Bas

elin

e E

colo

gica

l Ris

k A

sses

smen

tB

TA

GB

iolo

gica

l Tec

hnic

al A

dvis

ory

Gro

up.

CP

EC

Che

mic

als

of p

oten

tial

eco

logi

cal c

once

rn.

End

poin

tsR

EP

= r

epro

duct

ion;

GR

O =

gro

wth

; MO

R =

mor

tali

tyN

AN

ot a

ppli

cabl

e; T

RV

s re

quir

ed f

or b

adge

r ex

pose

d to

dee

p so

il o

nly.

TE

QT

oxic

equ

ival

ent q

uoti

ent.

TR

VT

oxic

ity

refe

renc

e va

lue.

-N

ot a

vail

able

.a

Fro

m E

coS

SL

Gui

dnce

(U

SE

PA

, 200

7).

bF

rom

OR

NL

Rep

ort (

Sam

ple

et a

l., 1

996)

.c

Low

TR

Vs

are

base

d on

NO

AE

L a

nd h

igh

TR

Vs

are

base

d on

LO

AE

L.

dR

epor

ted

NO

AE

L v

alue

s ar

e us

ed a

s th

e lo

w T

RV

and

the

"Dos

e"

(i.e

., be

fore

unc

erta

inty

fac

tors

wer

e ap

plie

d) r

epor

ted

is u

sed

as th

e hi

gh T

RV

.

Rep

orte

d L

OA

EL

val

ues

are

used

as

the

high

TR

V a

nd a

UF

of

10 a

ppli

ed to

cal

cula

te

the

low

TR

V.

Not

e: s

ome

of th

e T

RV

s li

sted

in th

is r

efer

ence

may

not

be

appr

opri

ate.

e

Ben

zo(a

)pyr

ene

valu

es u

sed

as s

urro

gate

for

hig

h m

olec

ular

wei

ght P

AH

s.f

Nap

htha

lene

val

ues

used

as

surr

ogat

e fo

r al

l low

mol

ecul

ar w

eigh

t PA

Hs.

gde

rive

d fo

r th

e B

ER

A a

s de

scri

bed

in A

ttac

hmen

t 2h

Nav

y/B

TA

G T

RV

wor

kgro

up s

elec

ted

biol

ogic

al e

ffec

ts th

at p

rim

aril

y re

late

d to

gro

wth

,

repr

oduc

tion

, and

dev

elop

men

t; h

owev

er, a

ll e

ffec

ts d

eem

ed e

colo

gica

lly

rele

vant

wer

e

cons

ider

ed w

hen

deve

lopi

ng T

RV

s.i

Dib

utyl

tin

and

trib

utyl

tin

valu

e us

edj

But

anol

use

d as

a s

urro

gate

for

TR

V d

eriv

atio

n.k

End

osul

fan

used

as

surr

ogat

e fo

r T

RV

der

ivat

ion

lN

-nit

roso

dim

ethy

lam

ine

used

as

surr

ogat

em

Di-

n-bu

tylp

htha

late

val

ues

used

as

a su

rrog

ate

n1,

2-D

ichl

oroe

than

e va

lue

used

as

surr

ogat

e.

oM

CP

A s

urro

gate

use

d.p

2,4-

DB

sur

roga

te u

sed.

qB

enze

ne v

alue

s us

ed a

s su

rrog

ate.

rB

utan

ol u

sed

as a

sur

roga

te f

or T

RV

der

ivat

ion.

sL

inda

ne (

gam

ma-

HC

H)

surr

ogat

e us

ed.

tA

UF

of

0.1

was

app

lied

to e

xtra

pola

te a

hig

h T

RV

fro

m th

e N

OA

EL

-bas

ed T

RV

.u

Acr

ylon

itri

le u

sed

as s

urro

gate

.v

Bas

ed o

n 2,

3,7,

8-te

trac

hlor

odib

enzo

diox

in (

TC

DD

).w

Chl

orob

enze

ne u

sed

as s

urro

gate

.x

MT

BE

use

d as

sur

roga

te.

yH

epta

chlo

r us

ed a

s su

rrog

ate

zF

rom

Cal

EP

A G

uida

nce

(Cal

EP

A, 2

002)

.

CS

CJa

nuar

y 20

11A

tt 2

Tab

les_

Fin

al R

IR_J

an 2

011_

1216

10.x

ls1

of 3

Fin

al R

emed

ial I

nves

tiga

tion

Rep

ort

Tab

le U

.A2-

4.S

umm

ary

of T

oxic

ity

Ref

eren

ce V

alue

s fo

r W

ildlif

e

Sou

rces

of

TR

Vs

(TR

Vs

obta

ined

fro

m s

econ

dary

sou

rces

and

pri

mar

y so

urce

s li

sted

bel

ow; s

ee A

ttac

hmen

t 2 te

xt f

or a

ll o

ther

ref

eren

ces)

:

Chu

, I.,

D.C

. Vil

lene

uve,

and

B.L

. Mac

Don

ald.

198

1b. R

ever

sibi

lity

of

the

toxi

colo

gica

l cha

nges

indu

ced

by p

hoto

mir

ex a

nd m

irex

. Tox

icol

ogy

21:2

35-2

50.

Blo

od, F

.R. 1

965.

Chr

onic

toxi

city

of

ethy

lene

gly

col i

n th

e ra

t. F

ood

Cos

met

. Tox

icol

. 3: 2

29-2

34.

And

erso

n, L

.M.,

A. G

iner

-Sor

olla

, D. E

beli

ng. 1

978.

Eff

ects

of

imip

ram

ine,

nit

rite

, and

dim

ethy

lnit

rosa

min

e on

rep

rodu

ctio

n in

mic

e, R

es C

omm

un C

hem

Pat

hol P

harm

acol

19:

311-

327.

Arn

old,

D.L

., C

.A. M

oodi

e, a

nd S

.M. C

harb

onne

au.

1985

. L

ong-

term

toxi

city

of

hexa

chlo

robe

nzen

e in

the

rat a

nd th

e ef

fect

of

diet

ary

Vit

amin

A.

Fd.

Che

m. T

oxic

. 23(

9):7

79-7

93.

Cal

EP

A. 2

002.

Rev

ised

U.S

. Env

iron

men

tal P

rote

ctio

n A

genc

y (U

SE

PA

) R

egio

n 9

Bio

logi

cal T

echn

ical

Ass

ista

nce

Gro

up (

BT

AG

) M

amm

alia

n T

oxic

ity

Ref

eren

ce V

alue

s (T

RV

) fo

r L

ead:

Ju

stif

icat

ion

and

Rat

iona

le. E

colo

gica

l Ris

k A

sses

smen

t Not

e 5

(Eco

Not

e 5)

. Cal

ifor

nia

Env

iron

men

tal P

rote

ctio

n A

genc

y, D

epar

tmen

t of

Tox

ic S

ubst

ance

s C

ontr

ol, H

uman

and

Eco

logi

cal

Ris

k A

sses

smen

t Div

isio

n. N

ovem

ber

21.

Chu

, I.,

D.C

. Vil

lene

uve,

and

V.E

. Val

li. 1

981a

. Chr

onic

toxi

city

of

phot

omir

ex in

the

rat.

Tox

icol

App

l Pha

rmac

ol 5

9:26

8-27

8.

Chu

n, J

.S.,

H.D

. Bur

leig

h-F

laye

r, a

nd W

.J. K

inti

gh.

1992

. M

ethy

l Ter

tiar

y B

utyl

Eth

er: V

apor

Inh

alat

ion

Onc

ogen

icit

y S

tudy

in F

isch

er 3

44 R

ats

(unp

ubli

shed

mat

eria

l).

Pre

pare

d fo

r th

e M

TB

E C

omm

itte

e by

Bus

hy R

un R

esea

rch

Cen

ter,

Uni

on C

arbi

de C

hem

ical

s an

d P

last

ics

Com

pany

Inc

. Doc

ket N

o. O

PT

S-4

2098

.

Dow

Che

mic

al C

ompa

ny. 1

981.

MR

ID N

o. 0

0152

675.

Ava

ilab

le f

rom

EP

A. W

rite

to F

OI,

EP

A, W

ashi

ngto

n D

.C. 2

0460

. Cit

ed in

IR

IS d

atab

ase.

Ero

sche

nko,

V.P

. and

T.A

. Pla

ce.

1977

. P

rolo

nged

eff

ects

of

kepo

ne o

n st

reng

th a

nd th

ickn

ess

of e

ggsh

ells

fro

m J

apan

ese

quai

l fed

dif

fere

nt c

alci

um le

vel d

iets

. E

nvir

on. P

ollu

t. 13

:255

-26

4.

Fie

ld E

.A.,

C.J

. Pri

ce, a

nd R

.B. S

leet

. 19

93.

Dev

elop

men

tal t

oxic

ity

eval

uati

on o

f di

ethy

l and

dim

ethy

l pht

hala

te in

rat

s. T

erat

olog

y 48

:33-

44.

Har

din,

B.D

., G

.P. B

ond,

M.R

. Sik

ov, F

.D. A

ndre

w, R

.P. B

elil

es a

nd R

.W. N

iem

eir.

198

1. T

esti

ng o

f se

lect

ed w

orkp

lace

che

mic

als

for

tera

toge

nic

pote

ntia

l. S

cand

. J. W

ork

Env

iron

. H

ealt

h. 7

(Sup

pl. 4

): 6

6-75

.

Hel

lwig

, J.,

C. G

emba

rdt,

S. J

asti

. 200

2. T

etra

hydr

ofur

an: t

wo-

gene

rati

on r

epro

duct

ion

toxi

city

in W

ista

r ra

ts b

y co

ntin

uous

adm

inis

trat

ion

in th

e dr

inki

ng w

ater

. Foo

d an

d C

hem

ical

T

oxic

olog

y. 4

0: 1

515-

1523

.

Hil

l, E

.F.,

R.G

. Hea

th, J

.W. S

pann

, and

J.D

. Wil

liam

s. 1

975.

Let

hal D

ieta

ry T

oxic

itie

s of

Env

iron

men

tal P

ollu

tant

s to

Bir

ds U

.S.F

ish

and

Wil

dlif

e S

ervi

ce, S

peci

al S

cien

tifi

c R

epor

t-W

ildl

ife

191:

1-61

.

Indu

stry

Tas

k F

orce

on

MC

PA

Res

earc

h D

ata,

198

6a. M

RID

No.

400

4170

1. U

npub

lish

ed m

ater

ial c

ited

by

IRIS

; ava

ilab

le f

rom

EP

A b

y F

OI.

Indu

stry

Tas

k F

orce

on

MC

PA

Res

earc

h D

ata,

198

6b. M

RID

No.

001

5215

2, 0

0164

352.

Unp

ubli

shed

mat

eria

l cit

ed b

y IR

IS; a

vail

able

fro

m E

PA

by

FO

I.

Kir

k, H

.D.,

T.R

. Han

ley,

K.A

. Joh

nson

and

F.K

. Die

tz. 1

989.

Pro

pyle

ne d

ichl

orid

e: O

ral t

erat

olog

y st

udy

in S

prag

ue-D

awle

y ra

ts. M

amm

alia

n an

d E

nvir

onm

enta

l Tox

icol

ogy

Res

earc

h L

abor

ator

y, H

ealt

h an

d E

nvir

onm

enta

l Sci

ence

s, T

he D

ow C

hem

ical

Com

pany

, Mid

land

, MI.

Kla

unig

J.E

., R

.J. R

uth,

and

M.A

. Per

eira

. 19

86.

Car

cino

geni

city

of

chlo

rina

ted

met

hane

and

eth

ane

com

poun

ds a

dmin

iste

red

in d

rink

ing

wat

er to

mic

e. E

nvir

on. H

ealt

h P

ersp

ect.

69:8

9-95

.

Kna

pp, W

.K.,

W.M

. Bus

ey a

nd W

. Kun

dzin

s. 1

971.

Sub

acut

e or

al to

xici

ty o

f m

onoc

hlor

oben

zene

in d

ogs

and

rats

. Tox

icol

. App

l. P

harm

acol

. 19:

393

Mar

quar

dt. 1

960.

Cit

ed in

IR

IS (

US

EP

A, 2

007b

) an

d In

form

atic

s, I

nc.,

1972

. GR

AS

(G

ener

ally

Rec

ogni

zed

as S

afe)

Foo

d In

gred

ient

s: B

enzo

ic A

cid

and

Sod

ium

Ben

zoat

e. p

. 75-

79.

NA

S. 1

977.

Dri

nkin

g W

ater

and

Hea

lth,

Nat

iona

l Aca

dem

y of

Sci

ence

s. V

ol. 1

. NA

S, W

ashi

ngto

n, D

C.

NC

I. 1

978.

Bio

assa

y of

1,2

-Dib

rom

oeth

ane

for

Pos

sibl

e C

arci

noge

nici

ty. B

ethe

sda,

MD

: Nat

iona

l Can

cer

Inst

itut

e. N

TIS

no.

PB

288

428

CS

CJa

nuar

y 20

11A

tt 2

Tab

les_

Fin

al R

IR_J

an 2

011_

1216

10.x

ls2

of 3

Fin

al R

emed

ial I

nves

tiga

tion

Rep

ort

Tab

le U

.A2-

4.S

umm

ary

of T

oxic

ity

Ref

eren

ce V

alue

s fo

r W

ildlif

e

NT

P. 1

993.

Tec

hnic

al R

epor

t on

toxi

city

stu

dies

of

sodi

um c

yani

de (

CA

S N

o. 1

43-3

3-9)

adm

inis

tere

d in

dri

nkin

g w

ater

to F

344/

N r

ats

and

B6C

3Fl m

ice.

Res

earc

h T

rian

gle

Par

k, N

C:

Nat

iona

l Tox

icol

ogy

Pro

gram

, U.S

. Dep

artm

ent o

f H

ealt

h an

d H

uman

Ser

vice

s, P

ubli

c H

ealt

h S

ervi

ce, N

atio

nal I

nsti

tute

s of

Hea

lth.

NIH

Pub

lica

tion

94-

3386

. NT

P T

OX

37.

NT

P. 2

000.

NT

P te

chni

cal r

epor

t on

the

toxi

city

stu

dies

of

1,1,

1-tr

ichl

oroe

than

e ad

min

iste

red

in m

icro

caps

ules

in f

eed

to F

344/

N r

ats

and

B6C

3F1

mic

e. N

atio

nal T

oxic

olog

y P

rogr

am. (

41)

NIH

004

402.

Par

ent R

.A.,

H.E

. Car

avel

lo, a

nd J

.E. L

ong.

199

2. T

wo-

year

toxi

city

and

car

cino

geni

city

stu

dy o

f ac

role

in in

rat

s. J

App

l Tox

icol

12(

2):1

31-1

39.

Pay

nter

, O.E

., T

.W. T

usin

g, D

.D. M

cCol

list

er a

nd V

.K. R

owe.

196

0. T

oxic

olog

y of

Dal

apon

Sod

ium

(2,

2-di

chlo

ropr

opoi

onic

aci

d, s

odiu

m s

alt)

. J. A

gric

ultu

re F

ood

Che

mic

als.

8: 4

7-51

.

Rho

dia,

Inc

. 196

9. M

RID

009

2165

. Unp

ubli

shed

mat

eria

l cit

ed b

y IR

IS; a

vail

able

fro

m E

PA

by

FO

I.

Sam

ple,

B.E

., D

.M. O

pres

ko, a

nd G

.W. S

uter

II.

199

6. T

oxic

olog

ical

Ben

chm

arks

for

Wil

dlif

e:19

96 R

evis

ion.

ES

/ER

/TM

-86-

R3.

Oak

Rid

ge N

atio

nal L

abor

ator

y. J

une.

Sm

ith,

F.A

., F

.J. M

urra

y, J

.A. J

ohn,

et a

l. 19

81. T

hree

-gen

erat

ion

repr

oduc

tion

stu

dy o

f ra

ts in

gest

ing

2,4,

5-tr

ichl

orop

enox

yace

tic

acid

in th

e di

et. T

oxic

ol. R

es. L

ab.,

Dow

Che

mic

al,

Mid

land

, MI.

Sti

ckel

, W.H

., J.

A. G

alye

n, R

.A. D

ryla

nd, a

nd D

.L. H

ughe

s. 1

973.

Tox

icit

y an

d P

ersi

sten

ce o

f M

irex

in B

irds

Pes

tic.

Env

iron

. :C

-467

.

US

EP

A. 1

986.

But

anol

: Rat

Ora

l Sub

chro

nic

Tox

icit

y S

tudy

. U

.S. E

nvir

onm

enta

l Pro

tect

ion

Age

ncy

Off

ice

of S

olid

Was

te, W

ashi

ngto

n, D

C.

Wol

f M

A, V

.K. R

owe,

D.D

. McC

olli

ster

, et a

l. 19

56. T

oxic

olog

ical

stu

dies

of

cert

ain

alky

late

d be

nzen

es a

nd b

enze

ne: E

xper

imen

ts o

n la

bora

tory

ani

mal

s. A

MA

Arc

h In

d H

ealt

h 14

:387

-39

8.

US

AC

HP

PM

. 200

6. W

ildl

ife

Tox

icit

y R

efer

ence

Val

ues.

US

Arm

y C

ente

r fo

r H

ealt

h P

rom

otio

n an

d P

reve

ntiv

e M

edic

ince

htt

p://

chpp

m-w

ww

.apg

ea.a

rmy.

mil

/era

wg/

tox/

inde

x.ht

m;

acce

ssed

Jun

e 20

07.

US

FW

S.

1975

. Let

hal D

ieta

ry T

oxic

itie

s of

Env

iron

men

tal P

ollu

tant

s to

Bir

ds. U

.S. F

ish

and

Wil

dlif

e S

ervi

ce D

epar

tmen

t of

the

Inte

rior

, Spe

cial

Sci

enti

fic

Rep

ort -

Wil

dlif

e N

o. 1

91.

Was

hing

ton,

DC

. p. 1

6

US

EP

A. 1

999.

Scr

eeni

ng L

evel

Eco

logi

cal R

isk

Ass

essm

ent P

roto

col f

or H

azar

dous

Was

te C

ombu

stio

n F

acil

itie

s. P

eer

Rev

iew

Dra

ft.

Aug

ust.

US

EP

A.

2000

. Off

ice

of P

esti

cide

Pro

gram

s. O

ffic

e of

Pes

tici

de P

rogr

ams,

Pes

tici

de E

coto

xici

ty D

atab

ase

(For

mer

ly: E

nvir

onm

enta

l Eff

ects

Dat

abas

e (E

ED

B))

Env

iron

men

tal F

ate

and

Eff

ects

Div

isio

n, W

ashi

ngto

n, D

.C. A

vail

able

in U

SE

PA

EC

OT

OX

dat

abas

e.

US

EP

A. 2

007.

Gui

danc

e fo

r D

evel

opin

g E

colo

gica

l soi

l scr

eeni

ng L

evel

s (E

coS

SL

s). O

ffic

e of

Sol

id W

aste

and

Em

erge

ncy

Res

pons

e, W

ashi

ngto

n D

.C. 2

005

Rev

isio

n, u

pdat

ed D

ecem

ber

2006

. 85

pp. h

ttp:

//w

ww

.epa

.gov

/eco

tox/

ecos

sl

Wei

sbur

ger,

E.K

., B

.M. U

llan

d, J

. Nam

, J.J

. Gar

t, an

d J,

H, W

eisb

urge

r. 1

981.

Car

cino

geni

city

test

s of

cer

tain

env

iron

men

tal a

nd in

dust

rial

che

mic

als.

Jou

rnal

Nat

iona

l Can

cer

Inst

itut

e 67

:75-

88.

CS

CJa

nuar

y 20

11A

tt 2

Tab

les_

Fin

al R

IR_J

an 2

011_

1216

10.x

ls3

of 3

Fin

al R

emed

ial I

nves

tiga

tion

Rep

ort

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