autotuning electronics for varactor tuned, flexible interventional rf coils
DESCRIPTION
Autotuning Electronics for Varactor Tuned, Flexible Interventional RF Coils. Ross Venook, Greig Scott, Garry Gold, and Bob Hu. Introduction. Basics of Magnetic Resonance Imaging (MRI) Motivation Why use interventional coils? Why is this hard? Background History RF coil tuning method(s) - PowerPoint PPT PresentationTRANSCRIPT
Autotuning Electronics for Varactor Tuned, Flexible Interventional RF
Coils
Ross Venook, Greig Scott,
Garry Gold, and Bob Hu
Introduction
• Basics of Magnetic Resonance Imaging (MRI)• Motivation
– Why use interventional coils?
– Why is this hard?
• Background– History
– RF coil tuning method(s)
• What we tried– Modular electronics discussion
• Results• Next steps
The First Thing About MRI
• Bloch Equation:
ω = γB• ω : precession/Larmor frequency
• γ : gyromagnetic ratio (2π•42.575MHz/Tesla)
• B : local magnetic field strength (Tesla)
z
x
y Bω
B
Hydrogen atom“spin”
z
x
y
The Second Thing About MRI
• During relaxation, the spins emit EM radiation at ω = γBlocal
• RF coil inductively couples this signal
z
x
yB ω
Before RF Excitation
z
x
y
Transversecomponent
RF Excitation“Tip”
RF Relaxation
Simple Example
• Linear gradient produces frequency encoding of spatial hydrogen atom distribution
Boz
y
x
+
By-gradient
=
Bfinal
Object
ωωo
Signal
Relaxation Signal (freq. domain)
Other Important Points
• Signal to Noise Ratio (SNR) is the figure of merit for MRI– SNR acts as a currency for other MRI attributes
(resolution, field of view, scan time)
• Clinically-driven field– Focus on medical problems/solutions– Factors of two matter
• Primary advantage of MRI: it is a non-invasive imaging modality
Why Use Interventional Coils?
• Increased signal coupling & reduced noise coupling better SNR
Coupled noise
Coupled signal
SNR Comparison
Applications: Existing and Potential
• Existing– Intravascular coils – Endorectal coils
• Potential– Inter-articular– <add your application here>
Why Interventional Coils Are Harder to Use: Dynamic loading
• Proximity works both ways– Closer coupling also means greater local tissue
dependency– Requires deployability in some applications
• Scaling works both ways– Human-scale effects are significant– Geometry more important
So…
• Dynamic loading conditions require dynamic tuning to maximize SNR advantages with interventional coils
• The tuning process should be automatic, and must add neither noise nor interference to the acquired signal
“RF Coils”
• RF transmitters and receivers (in MR) are magnetic field coupling resonators that are tuned to the Larmor frequency
• Examples:– Saddle– Surface – Interventional
3” surface coil (GE)
Resonance
• ‘Parallel RLC’ circuit
• Governing equation
• Familiar result
011
2
2
VLCdt
dV
RCdt
Vd
LCf
1
2
10
Impedance of Resonant Circuits
50 55 60 65 70 750
10
20
30
40
50
60
Frequency [MHz]
Res
ista
nce
[Ohm
s]
50 55 60 65 70 75-30
-20
-10
0
10
20
30
Frequency [MHz]
Rea
ctan
ce [
Ohm
s]
Goals: Tuning and Matching
• Tuning– Center Frequency near Larmor– Bandwidth appropriate to application
• Matching– Tuned impedance near 50 + j0 ohms
Complications
• Loading the coil with a sample necessarily creates coupling (it better!)
• Dynamic coupling creates dynamic tuning/matching conditions
TunedDetuned
History
• Tuning MRI coils (Boskamp 1985)
• Automatic Tuning and Matching (Hwang and Hoult, 1998)
• IV Expandable Loop Coils (Martin, et al, 1996)
Shoulders
• Varactor Tuned Flexible Interventional Receiver Coils (Scott and Gold, ISMRM 2001)
Cadaver Shoulder, 1.5T
3D/SPGR/20 slices
6cm FOV, 512x512
Greig’s Tunable Coil
22 or 68pFVaractor
150pF
<360nH
Flex coil
20K 20K
9 Vmanual
tune10K
C DC bias,RF isolate
75nH
Q spoil Rcv
PortC
2.5
cm ~15 cm
Pull wire
2 turns
Basic Tuning Method
• Manually change DC bias on varactor• Maximize magnitude response
– FID is a reasonable measure
Drawbacks:• Requires manual iterative approach• Maximum FID may not correspond to
maximum SNR• Feedback not effective with maximization
A Better Method Using Phase
• Zero-crossing at resonant frequency
50 55 60 65 70 750
10
20
30
40
50
60
Frequency [MHz]
Res
ista
nce
[Ohm
s]
50 55 60 65 70 75-30
-20
-10
0
10
20
30
Frequency [MHz]
Rea
ctan
ce [
Ohm
s]
50 55 60 65 70 750
10
20
30
40
50
60
Frequency [MHz]
Res
ista
nce
[Ohm
s]
50 55 60 65 70 75
-20
-10
0
10
20
30
Frequency [MHz]
Rea
cta
nce
[Ohm
s]
50 55 60 65 70 750
10
20
30
40
50
60
Frequency [MHz]
Res
ista
nce
[Ohm
s]
50 55 60 65 70 75
-20
-10
0
10
20
30
Frequency [MHz]
Rea
cta
nce
[Ohm
s]
50 55 60 65 70 750
10
20
30
40
50
60
Frequency [MHz]
Res
ista
nce
[Ohm
s]
50 55 60 65 70 75
-20
-10
0
10
20
30
Frequency [MHz]
Rea
cta
nce
[Ohm
s]
At 63.9MHz
Measuring Phase Offset
coil
Vo>0
Vo=0
Vo<0
Cref
Sig
nal so
urc
e Va
Vb
+_
_+
AD835250 MHzMultiplier
Vo
Vo=|Va||Vb|cos(Φ) + …
Filter
Vo ~ |Va||Vb|cos(Φ)
What We Tried
Phase Comparator
coil
CrefVa
Vb
++
_
_
AD835250 MHzMultiplier
Vo
Filter
Vo ~ |Va||Vb|cos(Φ) Vo ~ cos(Φ)
Old New
Vo
Phase Detector ResultsMultiplier Output vs. Receiver Center Frequency
Half-wavelength Txn Line
-600-500-400-300-200-100
0100200300400500
55 57 59 61 63 65 67 69
Frequency (MHz)
DC
out
put (
mV
)
Phase Detector Results (cont…)
• λ/4
• 3λ/8
• 5λ/8
-600
-500
-400
-300
-200
-100
0
55 57 59 61 63 65 67 69
Frequency (MHz)
0
100
200
300
400
500
600
700
DC
ou
t (m
v)_
__
0
100
200
300
400
500
600
Closed Loop Feedback?
• Tempting…– Simple DC negative feedback about zero-point
• …but unsuccessful– Oscillations– Railing
• Phase detection scheme probably requires a different method (?)
Microcontroller
• Why use a microcontroller?– Controlling reference signal generation– Opportunity for tuning algorithms
• Atmel AT90S8515– Serial Peripheral Interface– Analog Comparator– Simple
Atmel AT90S8515
• Serial Peripheral Interface
• Analog Comparator
• Simple development platform– STK500: Starter Kit– CVAVR: C compiler
Reference Signal Requirements
• Accurate and stable reference signal at Larmor frequency during tuning
• Signal well above Larmor frequency during receive mode
PLL Synthesizer
• Phase Locked Loop– Frequency to voltage
• Voltage-Controlled Oscillator– Voltage to frequency
• Current Feedback Amplifier– “Tri-statable:” turns off signal
• Low Pass Filter– Cleans VCO output
Tune/Receive (TR) Switch
• Loading effects categorically harmful
• Ideal
– Complete isolation of tuning and receiving circuitry
TuningCircuit
Scanner
Actual TR Switches
• PIN-diodes control signal direction• RF chokes ensure high-impedance, reduce loading
Scanner
TuningCircuit
Microcontroller
Complete System
Results
• Basic tuning functionality– 300ms total tuning time
Detuned
Retuned
Retuned
Detuned
Next Steps
• Get an image with autotuned receiver on 1.5T scanner
• SNR advantage (validation) experiments
• Minimize tuning time
• Explore VSWR bridge tuning– Remove need for λ/2 cable restriction