avian influenza h5n1 reactive antibodies ba 468x technology commercialization
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Avian Influenza H5N1
Reactive AntibodiesBA 468x
Technology Commercialization
Christopher Bush Computer Science, Entrepreneurship
Kevin Irish Marketing, Multimedia, Entrepreneurship
Kyle Winkler Construction Engineering Management, Entrepreneurship
Dr. Manoj Pastey Inventor, Assistant Professor of Veterinary Medicine
Rob Schneider Mentor, Self Employed
Sukanya Rengaswamy Mentor, Hewlett-Packard
The Team
Source: Foreign Agricultural Service/USDA Office of Global Analysis, April 2007 http://www.who.int/csr/disease/avian_influenza/en/index.html
Definition & Status
• Avian Influenza H5N1 “Bird Flu” & H7N2 virus• Found in wild ducks & geese (host)
• Spread by droppings and nasal fluids• Highly pathogenic in poultry• High fatality rate
What is Bird Flu?
Current Status• Over 150 million birds destroyed• 291 human cases / 172 human deaths• Stage 3 of 6 WHO Global Pandemic Alert
Spread of Avian Influenza
Bird MigrationH5N1 Outbreaks
Global Distribution Channels Since 2003, human cases of avian flu has been
confirmed in 12 countries, and has been found in animals in 40 countries:
Why License?
Source: WHO
Speed to Market 6 countries have reported avian influenza deaths in
2007.
Complimentary product Diagnostic companies have a wide range of testing
products.
Our Technology
Antibodies to specifically detect the deadly H5N1 and H7N2 strains
Easy to incorporate into existing “on-site” tests Used for chickens and humans Results in 10 minutes Easy to use
Why We Win
Current Lab Test
AvianLabs
Antibodies
Current Field Test
Positive
Positive
Field Test
$13 + Shipping
15 min – 1 hour
Generic Flu Virus
On-site
Moderate
AvianLabs
$13 + Shipping
10 min
H5N1 & H7N2
On-site
Low
Lab Test
$120
3 days – 1 week
H5 & H7 Strains
Off-site
Very High
Cost
Time
Specificity
Location
Complexity
Proof of ConceptProof of Concept
Finalize Patent Claims – 6 moCompletion of R&D – 6 mo
Licensee Internal Review – 2 moLicensing Negotiations – 4 mo
Initial Marketing/Sales – 6 mo
Manufacturing ramp up – 8 mo
Prototyping Product Intro. Manf. Ramp
Technology Timeline
USDA Research Grant Awarded
Prototyping Product Intro. Manf. Ramp
Initial R&D – 8 moResearch Potential Licensees – 2 mo
20082007 20092006
Target Market
Governments Monitor Migratory Wild Birds Prevent Spread into Country Protect its citizens Prevent Global Pandemic Regulate Poultry Industry
Farmers Target Market Prevent Large Scale Economic Loss Provides “Insurance” Policy
Testing Market
Migratory Wild Bird Testing
Poultry Testing
FarmersGovernments/
RegulatoryAgencies
Governments/RegulatoryAgencies
Sales ForecastAssumptions:
•6 Billion Chickens (Asia)•0.5% - 1.0% tested monthly
Source: Cheok Soh Hui, ICIS Chemical Business, 2006
In millions excluding “price per kit”
YearMarket
Potential
% Increase of Chicken Production
Est. Market Share
# of Tests
Price per Test Revenue
1 360 - 5.00% 18 $13.00 $2342 364 1.00% 9.00% 33 $12.50 $4093 367 1.00% 14.00% 51 $12.00 $6174 371 1.00% 16.00% 59 $11.50 $6825 375 1.00% 18.00% 67 $11.00 $742
Revenue Forecast
All $ in millions Excluding “price per kit”
Year 0 1 2 3 4 5Unit Sales 0.0 18.0 32.7 51.4 59.3 67.4
x Price per test $13.00 $12.50 $12.00 $11.50 $11.00
= Revenue $0.0 $234.0 $409.1 $617.0 $682.5 $741.7
- Royalty Fees $0.15 $11.0 $19.2 $29.0 $32.1 $34.9
Gross Profit $0.0 $124.0 $216.8 $327.0 $361.7 $393.1
Operating Profit ($0.2) $35.1 $61.4 $92.5 $102.4 $111.3
Net Profit ($0.2) $19.8 $34.5 $52.0 $57.5 $62.5
Net Cash Flow ($5.2) $20.9 $35.7 $53.2 $58.8 $63.8
Cumulative Cash Flow ($5.2) $15.7 $51.4 $104.6 $163.4 $227.2
Current Issues/Future Potential
Issues SolutionsVirus Mutations
Technology IP
Lab Predictions Escape Mutants
Currently Strengthening Claims
Future Markets & Potential•Customs (Border Crossings)•All Species•Human Antivirals & Vaccines
Contact Information
Thank you for allowing us to present our technology.
Questions or Comments?Christopher Bush
Kevin Irish [email protected]
Kyle Winkler [email protected]