awadhes final report 1

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    A DISSERTATION ON

    Protective Effect of Boerhaavia diffusa root extract on tissue lipid level and

    antioxidant defence system in STZ induced diabetic rats

    SUBMITTED TO THE

    DEPARTMENT OF BIOSCIENCES

    INTEGRAL UNIVERSITY, LUCKNOW

    IN PARTIAL FULFILMENT FOR THE

    DEGREE OF MASTER OF SCIENCE IN BIOCHEMISTRY

    BY

    AWADHESH KUMAR YADAV

    M. Sc. Biotechnology (IV semester)

    Department of Biosciences

    Integral University, Lucknow

    UNDER THE SUPERVISION OF

    Dr. M. Salman Khan

    Associate Professor (Jr.), Department of Biosciences

    Integral University, Lucknow.

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    INTEGRAL UNIVERSITYEstablished Under U.P. Act No 09 of 2004 by State Legislation

    Approved by University Grants Commission

    Phone No.: +91 (0552) 2890812, 2890730, 3296117, 6451039,

    Fax No.: 0522-2890809

    Kursi Road, Lucknow-226026, Uttar Pradesh (INDIA)

    TO WHOM IT MAY CONCERN

    This is to certify that Mr. Awadhesh Kumar Yadav, a student of M.Sc. Biotechnology (2nd

    year/IVsemester), Integral University has completed his three months dissertation work

    entitled Protective Effect of Boerhaavia diffusa root extract on tissue lipid

    level and antioxidant defence system in STZ induced diabetic rats diabetic

    rats by Boerhaavia diffusa root extract. successfully. He has completed this work

    from Clinical Biochemistry and Natural Products Lab., Integral University under theguidance ofDr. M. Salman Khan. The dissertation was a compulsory part of his M. Sc.

    degree.

    I wish him good luck and bright future.

    Prof. (Dr.) A. K. Srivastava

    Head of the Department,

    Department of Biosciences,

    Integral University, Lucknow.

    E-mail: [email protected] Web: www.integraluniversity.ac.in

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    EEstablishedUnder the Integral University Act 2004 (U.P. Act No.9 of 2004)

    Approved by University Grant Commission

    Phone No.: +91(0522) 2890812, 2890730, 3296117, 6451039, Fax No.: 0522-2890809

    Kursi Road, Lucknow-226026 Uttar Pradesh (INDIA)

    Dr. M. Salman Khan, Ph. D.Date:

    [email protected]

    TO WHOM IT MAY CONCERN

    This is to certify that the study conducted byAwadhes kumar yadav during the months 1st Jan

    31st March, 2013 reported in the present thesis was under my guidance and supervision in

    Clinical Biochemistry and Natural Product lab (RL4). The results reported by his are genuine

    and script of the thesis has been written by the candidate hisself. The thesis entitled

    Protective Effect of Boerhaavia diffusa root extract on tissue lipid level and antioxidant

    defence system in STZ induced diabetic rats is therefore, being forwarded for the acceptance

    in partial fulfilment of the requirements for the award of the degree of Master of Science in

    Biotechnology, Department of Biosciences, Integral University, Lucknow, U.P.

    E-mail: [email protected] Web: www.integraluniversity.ac.in

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    ACKNOWLEDGEMENTS

    First of all I bow in reverence to the Almighty for blessing me with strong

    will power, patience and confidence, which helped me in completing the present

    work.

    I would like to express my deep sense of gratitude to Dr. M. Salman Khan

    (Department of Biosciences) for their invaluable guidance throughout the course

    of my dissertation work and academic session. It would have been impossible to

    complete this work in so short a time without his constant guidance. I wish every

    trainee and research student were fortunate enough to have such an affectionate

    guide.

    I would like to express my special thank to Prof. (Dr.) A.K. Srivastava

    (Associate Professor and Head, Department of Biosciences) for giving me an

    opportunity to join the department laboratory and providing all the necessary

    facilities ever since I started my work.

    I warmly thank to all the Ph.D Scholars of Department of Biosciences

    includingMr. FirozAkhter, Mr. Danish Iqbal, and Ms. ArshiyaHashim for their

    valuable advice and help whenever I needed. Everlasting thanks to my

    friendsLaxmi and ShafkatJahanfor their indispensable aid and prayers

    throughout the whole span of my training. My warm thanks to all the lab assistants

    and the supporting staff of the department who helped me in lab work.There kind

    support has been of great value in this project.

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    My acknowledgement will be incomplete if I do not mention my parents with

    whose blessing I was able to achieve my goal successfully. There are no words to

    express my feelings toward them. I silently acknowledge my debt to them.

    AWADHESH KUMAR YADAV

    M.Sc. ( BIOTECHNOLOGY)

    Final year

    Integral University, Lucknow