b. ch 42 circulation
TRANSCRIPT
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CH 42Circulatory Systems
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Exchange of materials
Animal cells exchange material acrosstheir cell membrane
fuels for energy
nutrients oxygen
waste (urea, CO2)
If you are a 1-cell organism thats easy! diffusion
If you are many-celled thats harder
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Overcoming limitations of diffusion
O2CHO
CHO
aa
aaCH
CO2NH3aa
O2
CH
aa
CO2 CO2
CO2CO2
CO2
CO2 CO2
CO2
CO2CO2
NH3
NH3 NH3NH3
NH3NH3
NH3NH3O2aaCH
aa
CHO
O2 Diffusion is not adequate for moving
material across more than 1-cell barrier
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In circulation
What needs to be transported nutrients & fuels
from digestive system
respiratory gases
O2 & CO2 from & to gas exchange systems: lungs, gills intracellular waste
waste products from cells
water, salts, nitrogenous wastes (urea)
protective agents
immune defenses white blood cells & antibodies
blood clotting agents
regulatory molecules hormones
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Circulatory systems
All animals have: circulatory fluid = blood
tubes = blood vessels
muscular pump = heartopen closed
hemolymph
blood
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Open circulatory system
Taxonomy invertebrates
insects,arthropods,mollusks
Structure
no separation
between blood &interstitial fluid
hemolymph
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Closed circulatory system
Taxonomy invertebrates
earthworms, squid,octopuses
vertebrates
Structure blood confined to
vessels & separatefrom interstitial fluid
1 or more hearts
large vessels to smallervessels
material diffusesbetween blood vessels& interstitial fluid
closed system = higher pressures
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Vertebrate circulatory system
Adaptations in closed system number of heart chambers differs
4 chamber heart is double pump = separates oxygen-rich &oxygen-poor blood; maintains high pressure
Whats the adaptive value of a 4 chamber heart?
2 3 4
lowpressureto body
low O2tobody
high
pressure& high O2to body
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Evolution of vertebrate circulatory system
fish amphibian reptiles birds & mammals
A A
V
V V VV
A AAA
A
V
2 chamber 3 chamber 3 chamber 4 chamber
Birds ANDmammals!
Wassssup?!
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Evolution of 4-chambered heart
convergentevolution
Selective forces increase body size
protection from predation
bigger body = bigger stomach forherbivores
endothermy can colonize more habitats
flight decrease predation & increase prey
capture Effect of higher metabolic rate
greater need for energy, fuels, O2,waste removal endothermic animals need 10x energy
need to deliver 10x fuel & O2 to cells
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Vertebrate cardiovascular system
Chambered heart atrium = receive blood
ventricle = pump blood out
Blood vessels arteries = carry blood away from heart
arterioles
veins = return blood to heart venules
capillaries = thin wall, exchange / diffusion
capillary beds = networks of capillaries
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Blood vessels
arteriesarterioles
capillariesvenules
veins
artery
arteriolesvenules
veins
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Arteries: Built for high pressure pump
Arteries thicker walls
provide strength for highpressure pumping of blood
narrower diameter
elasticity
elastic recoil helps
maintain bloodpressure evenwhen heart relaxes
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Veins: Built for low pressure flow
Veins thinner-walled
wider diameter blood travels back to heart
at low velocity & pressure
lower pressure distant from heart
blood must flow by skeletal muscle
contractions when we move squeeze blood through veins
valves in larger veins one-way valves
allow blood to flow only toward heart
Openvalve
Blood flows
toward heart
Closed valve
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Capillaries: Built for exchange
Capillaries very thin walls
lack 2 outer wall layers
only endothelium enhances exchange
across capillary
diffusion
exchange betweenblood & cells
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Controlling blood flow to tissues
Blood flow in capillaries controlled bypre-capillary sphincters
supply varies as blood is needed
after a meal, blood supply to digestive tract increases
during strenuous exercise, blood is diverted fromdigestive tract to skeletal muscles
capillaries in brain, heart, kidneys & liver usuallyfilled to capacity
sphincters open sphincters closed
Why?
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Exchange across capillary walls
Arteriole
Bloodflow
Venule
Lymphatic
capillary
Interstitialfluid
Fluid & solutes flowsout of capillaries totissues due to bloodpressure
bulk flow
Interstitial fluid flowsback into capillariesdue to osmosis plasma proteins osmotic
pressure in capillary
BP > OP BP < OP
15% fluid returnsvia lymph
85% fluid returnsto capillaries
What about
edema?
Capillary
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Lymphatic system
Parallel circulatory system transports white blood cells
defending against infection
collects interstitial fluid &returns to blood
maintains volume & proteinconcentration of blood
drains into circulatory systemnear junction of vena cava &right atrium
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Lymph systemProduction & transport of WBCs
Traps foreign invaders
lymph node
lymph vessels(intertwined amongst blood vessels)
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Mammalian
circulation
What do bluevs. red areas represent?
pulmonary
systemic
systemic
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Mammalian heart
Coronary arteries
to neck & head
& arms
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Coronary arteries
bypass surgery
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AV
SL
AV
Heart valves
4 valves in the heart flaps of connective tissue
prevent backflow
Atrioventricular (AV) valve
between atrium & ventricle keeps blood from flowing back
into atria when ventricles contract lub
Semilunar valves between ventricle & arteries
prevent backflow from arteries intoventricles while they are relaxing dub
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AV
SL
AV
Lub-dub, lub-dub
Heart sounds closing of valves
Lub
recoil of blood against
closed AV valves
Dub
recoil of blood againstsemilunar valves
Heart murmur defect in valves causes hissing sound when
stream of blood squirts backward through valve
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Cardiac cycle
systolic________
diastolic
pump(peak pressure)_________________
fill(minimum pressure)
1 complete sequence of pumping heart contracts & pumps
heart relaxes & chambers fill
contraction phase systole
ventricles pumps blood out
relaxation phase
diastole atria refill with blood
110____
70
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Measurement of blood pressure
High Blood Pressure (hypertension)
if top number (systolic pumping) > 150
if bottom number (diastolic filling) > 90