bando 2018 voto ipotesi residuo dopo finanziamento ...€¦ · classifica e finanziamento progetti...

BANDO 2018(fondo 2016-2017)

Classifica e Finanziamento Progetti RF Change Promoting

N. Code

Research

type Title

Voto finale

(VS+CV) IRG MDC Destinatario Budget Richiesto

MOH IPOTESI

FINANZIAMENTOResiduo dopo

Finanziamento

1RF-2018-12367807 CP

A case-control study on the association of dipeptidyl peptidase IV inhibitor (gliptin) treatment in type 2 diabetes and bullous pemphigoid 8,50

Musculoskeletal, Oral and Skin Sciences Dermatologia

ISTITUTO DERMOPATICO DELL'IMMACOLATA € 364.650,00 € 364.650,00 € 17.119.484,40

2RF-2018-12366314 CP

Whole Genome Sequencing into the diagnostic workflow of rare diseases: a cost-effectiveness evaluation in a heterogeneous population of patients with inconclusive Whole Exome Sequencing 9,50 Genes, Genomes and Genetics Pediatria GASLINI € 450.000,00 € 450.000,00 € 16.669.484,40

3RF-2018-12366868 CP

Phase II, multicenter, double blind, randomized controlled trial on "off the shelf" allogeneic Platelet Rich Plasma (PRP) to treat diabetic foot ulcers 10,50

Musculoskeletal, Oral and Skin Sciences Dermatologia

Ospedale Policlinico San Martino € 445.000,00 € 445.000,00 € 16.224.484,40

4RF-2018-12368274 CP

Impact of high tibial osteotomy in preventing disease progression in medial knee osteoarthritis: quantifying the effects on cartilage and subchondral bone by using a combined biomechanical and medical imaging approach 11,50

Musculoskeletal, Oral and Skin Sciences Ortopedia RIZZOLI € 449.900,00 € 449.900,00 € 15.774.584,40

5RF-2018-12365514 CP

DAILY TIME USE, PHYSICAL ACTIVITY, QUALITY OF CARE AND INTERPERSONAL RELATIONSHIPS IN PSYCHIATRIC RESIDENTIAL FACILITIES: AN ITALIAN MULTICENTRE STUDY 11,50

Healthcare Delivery and Methodologies Malattie Psichiatriche FATEBENEFRATELLI € 449.450,10 € 449.450,10 € 15.325.134,30

6RF-2018-12365527 CP

Ventral Tegmental Area dopaminergic midbrain: new therapeutic target in early Alzheimer's Disease. 11,50

Brain Disorders and Clinical Neuroscience Neurologia SANTA LUCIA € 449.667,00 € 449.667,00 € 14.875.467,30

7RF-2018-12366604 CP

'PRoSPECT': Predicting Salmonella Pathogenic Potential to Enhance Targeted Control Strategies 11,50 Veterinary Malattie Infettive IZSVE € 400.950,00 € 400.950,00 € 14.474.517,30

8RF-2018-12367534 CP

Prevalence and spatial distribution of endometriosis in Italy: administrative data and active search through a multistage screening survey 11,50

Healthcare Delivery and Methodologies Ostetricia e Ginecologia BURLO GAROFOLO € 444.200,00 € 444.200,00 € 14.030.317,30

1

Administrator

Evidenziato

gdegirolamo

Rettangolo

BANDO 2018(fondo 2016-2017)


N. Code

Research

type Title

Voto finale


MOH IPOTESI


Finanziamento

9RF-2018-12367150 CP

Development of a new diagnostic tool based on tumor-associated macrophages to refine the prognosis of patients undergoing hepatic resection for colorectal liver metastases: a prospective study. 12,00

Oncology 2 - Translational Clinical Oncologia HUMANITAS € 440.000,00 € 440.000,00 € 13.590.317,30

10RF-2018-12368399 CP

Development of a Novel Signature Integrating Clinical, Imaging And Epigenetic Information to Tailor Pelvic Nodal Treatment in Prostate Cancer 12,00

Oncology 2 - Translational Clinical Nefrologia e Urologia SAN RAFFAELE MILANO € 430.000,00 € 430.000,00 € 13.160.317,30

11RF-2018-12367080 CP

Liquid biopsy of semen for early detection and characterization of prostate cancer - Semen ProstatE Cancer TumoR Elements (SPECTRE) project 12,50

Oncology 2 - Translational Clinical Nefrologia e Urologia HUMANITAS € 450.000,00 € 450.000,00 € 12.710.317,30

12RF-2018-12366976 CP

Markers of oxidative stress in Inflammatory Bowel Disease in children and adults: risk factors and implications for a dietetic approach 12,50

Digestive, Kidney and Urological Systems Gastroenterologia Marche € 330.000,00 € 330.000,00 € 12.380.317,30

13RF-2018-12367090 CP

Cardiac Arrhythmia catheter ablation procedures guided by x-Ray imaging: N-Acetylcisteine Protection Against radiation induced Cellular damagE (CARAPACE Study). 12,50

Cardiovascular and Respiratory Sciences Cardiologia-Pneumologia MONZINO € 348.920,00 € 348.920,00 € 12.031.397,30

14RF-2018-12367604 CP

Circulating biomarkers as predictors of gender-specific response to Immune Checkpoint Inhibitors in melanoma and non-small-cell lung cancer patients 12,50

Oncology 2 - Translational Clinical Oncologia I. O. V. € 448.800,00 € 448.800,00 € 11.582.597,30

15RF-2018-12365682 CP

STAND-ALONE: "STand AND wALk". OptimiziNg the Embodiment and agency of the exoskeleton (EXO) in spinal cord injury patients (SCIp) 12,50

Integrative, Functional, and Cognitive Neuroscience Riabilitazione SANTA LUCIA € 450.000,00 € 450.000,00 € 11.132.597,30

2

BANDO 2018(fondo 2016-2017)


N. Code

Research

type Title

Voto finale


MOH IPOTESI


Finanziamento

16RF-2018-12365210 CP

The PROMOTOER: a Brain Computer Interface-based intervention that promotes upper limb functional motor recovery in subacute stroke patients. A randomized controlled trial protocol to test long-term efficacy and to identify determinants of response to inte 13,00

Brain Disorders and Clinical Neuroscience Riabilitazione SANTA LUCIA € 332.445,00 € 332.445,00 € 10.800.152,30

17RF-2018-12366931 CP

Emergency genomics: an informative tool to guide advanced precision medicine in Intensive Care Units 13,00 Genes, Genomes and Genetics Pediatria

OSPEDALE BAMBINO GESU' € 450.000,00 € 450.000,00 € 10.350.152,30

18RF-2018-12366746 CP

Tracking and predicting neurodegeneration along the Parkinson's Disease continuum using clinical, cognitive and advanced MRI data 13,00

Brain Disorders and Clinical Neuroscience Neurologia SAN RAFFAELE MILANO € 450.000,00 € 450.000,00 € 9.900.152,30

19RF-2018-12367391 CP

Integrated multidisciplinary approach for personalized management of patients with Spondyloarthritis and Inflammatory Bowel Disease. 13,50 Immunology Ematologia e Immunologia FONDAZIONE GEMELLI € 450.000,00 € 450.000,00 € 9.450.152,30

20RF-2018-12366098 CP

Liver Screening in the population of Veneto Region 13,50

Digestive, Kidney and Urological Systems Gastroenterologia Veneto € 450.000,00 € 450.000,00 € 9.000.152,30

21RF-2018-12366749 CP

Acute normovolemic hemodilution in high-risk cardiac surgery patients. A multicenter, randomized trial. 13,50

Surgical Sciences, Biomedical Imaging, and Bioengineering Cardiologia-Pneumologia SAN RAFFAELE MILANO € 450.000,00 € 450.000,00 € 8.550.152,30

22RF-2018-12365425 CP

Development of a biomarker to predict the efficacy of anti-angiogenic therapy in ovarian cancer. 13,50 Oncology 1 - Basic Translational Oncologia C.R.O. AVIANO € 450.000,00 € 450.000,00 € 8.100.152,30

23RF-2018-12365790 CP

Novel predictive biomarkers in the clinical management of ibrutinib-treated chronic lymphocytic leukemia patients: results form an observational prospective clinical trial 14,00

Oncology 2 - Translational Clinical Oncologia C.R.O. AVIANO € 450.000,00 € 450.000,00 € 7.650.152,30

24RF-2018-12367311 CP

PERSONALIZED MOLECULAR DRIVEN SURGERY ACCORDING TO BRCA MUTATIONAL STATUS IN ADVANCED EPITHELIAL OVARIAN CANCER PATIENTS WITH HIGH TUMOR LOAD 14,00

Oncology 2 - Translational Clinical Oncologia FONDAZIONE GEMELLI € 449.936,65 € 449.936,65 € 7.200.215,65

3

BANDO 2018(fondo 2016-2017)


N. Code

Research

type Title

Voto finale


MOH IPOTESI


Finanziamento

25RF-2018-12365371 CP

Ablation of the maladaptive ER stress response restores diaphragm function and insulin resistance in SEPN1-related myopathies 14,00

Musculoskeletal, Oral and Skin Sciences Neurologia MARIO NEGRI € 450.000,00 € 450.000,00 € 6.750.215,65

26RF-2018-12367026 CP

Preclinical and Clinical Development of a 68Ga-NOTA-AHX-R54, a CXCR4-PET tracer targeting tumoral and stromal cells in human solid cancers. First in Man Clinical Trial 14,00

Oncology 2 - Translational Clinical Oncologia PASCALE € 450.000,00 € 450.000,00 € 6.300.215,65

27RF-2018-12368001 CP

PROPHYBIOM TRIAL: PROPHYlactic Implantation of BIOlogic Mesh in peritonitis 14,00

Surgical Sciences, Biomedical Imaging, and Bioengineering Gastroenterologia Emilia-Romagna € 360.528,65 € 360.528,65 € 5.939.687,00

28RF-2018-12368096 CP

Targeting the future of axillary staging in early breast cancer. A prospective study comparing sentinel node biopsy vs PET/MRI 14,00

Surgical Sciences, Biomedical Imaging, and Bioengineering Oncologia SAN RAFFAELE MILANO € 450.000,00 € 450.000,00 € 5.489.687,00

29RF-2018-12366594 CP

Nerve growth factor in pediatric severe traumatic brain injury: translational and clinical studies on a candidate biomarker and therapeutic drug 14,00

Brain Disorders and Clinical Neuroscience Pediatria FONDAZIONE GEMELLI € 392.500,00 € 392.500,00 € 5.097.187,00

30RF-2018-12366235 CP

Novel approaches of advanced neuroimaging based on MRI fiber tracking to detect early signs of vascular cognitive impairment in hypertensive patients. 14,50

Brain Disorders and Clinical Neuroscience Cardiologia-Pneumologia NEUROMED € 408.000,00 € 408.000,00 € 4.689.187,00

31RF-2018-12367272 CP

Multimodal prehabilitation in colorectal cancer patients to improve functional capacity and lower postoperative complications: A randomized clinical trial. 14,50

Surgical Sciences, Biomedical Imaging, and Bioengineering Oncologia Emilia-Romagna € 360.000,00 € 360.000,00 € 4.329.187,00

32RF-2018-12366111 CP

multidimensional assessment of neurological and immunological patterns to test the efficacy and response to a novel therapy in multiple sclerosis 14,50


33RF-2018-12366631 CP

Safety and efficacy of a possible FSHD treatment 14,50 Genes, Genomes and Genetics Neurologia SAN RAFFAELE MILANO € 450.000,00 € 450.000,00 € 3.429.465,00

4

BANDO 2018(fondo 2016-2017)


N. Code

Research

type Title

Voto finale


MOH IPOTESI


Finanziamento

34RF-2018-12368164 CP

Identifying ageing TRajEctories towards chronic Neurodegenerative Diseases through Marche regional administrative databases - TREND 14,50

Healthcare Delivery and Methodologies Neurologia Marche € 400.000,00 € 400.000,00 € 3.029.465,00

35RF-2018-12365985 CP

SynErg. Synergies anchoring to gravity: A novel test to diagnose risk of falls in type 2 diabetes patients 14,50

Biobehavioral and Behavioral Processes Diagnostica SANTA LUCIA € 450.000,00 € 450.000,00 € 2.579.465,00

36RF-2018-12365530 CP

Epidemiological profiles and cost patterns of cancer patients (EpiCost2) 15,00

Healthcare Delivery and Methodologies Oncologia

Istituto Superiore di Sanita' € 308.000,00 € 308.000,00 € 2.271.465,00

37RF-2018-12365391 CP

Effects of long-term oral administration of palmitoylethanolamide on subjects with mild cognitive impairment 15,00


38RF-2018-12367340 CP

Haploidentical Bone Marrow Transplantation with or without NK cell Infusion in refractory/ relapsed Acute Myeloid Leukemia and Myelodysplastic Syndrome 15,00 Vascular and Hematology Ematologia e Immunologia FONDAZIONE GEMELLI € 447.500,00 € 447.500,00 € 1.373.965,00

39RF-2018-12365824 CP

Fasting mimicking diet as intervention tool to improve endogenous insulin secretion and reduce autoimmune process in children and adolescents with newly-diagnosed type 1 diabetes mellitus 15,00

Endocrinology, Metabolism, Nutrition and Reproductive Sciences Pediatria GASLINI € 449.978,26 € 449.978,26 € 923.986,74

40RF-2018-12365308 CP

Targeting inflammation in depression using minocycline: a patient stratification approach using peripheral inflammatory biomarkers, PET and MRI 15,00

Brain Disorders and Clinical Neuroscience Malattie Psichiatriche FATEBENEFRATELLI € 448.400,00 € 448.400,00 € 475.586,74

41RF-2018-12367835 CP

What is the best interval to screen women 45-49 and 70-74 for breast cancer? 15,00

Oncology 2 - Translational Clinical Oncologia

Istituto Scientifico Romagnolo € 450.000,00 € 450.000,00 € 25.586,74

42RF-2018-12365207 CP

NEW REHABILITATION APPROACH FOR MOVEMENT DISORDER, COMBINING NON INVASIVE STIMULATION, COMPUTER-BASED PLATFORM TRAINING AND TELEMONITORING 15,50

Emerging Technologies and Training in Neurosciences Neurologia MAGGIORE € 447.940,00 € -

5

BANDO 2018(fondo 2016-2017)


N. Code

Research

type Title

Voto finale


MOH IPOTESI


Finanziamento

43RF-2018-12366553 CP

Exploiting circulating levels of epithelial-to-mesenchymal transition transcription factors (EMT-TF) mRNAs for the diagnosis of colorectal and pancreatic cancer 15,50

Oncology 2 - Translational Clinical Oncologia HUMANITAS € 450.000,00 € -

44RF-2018-12365810 CP

Plasma cell free tumor DNA genotyping as a tool for the clinical management of diffuse large B-cell lymphoma: results from a prospective observational clinical trial 15,50

Oncology 2 - Translational Clinical Oncologia C.R.O. AVIANO € 450.000,00 € -

45RF-2018-12366802 CP

Reducing adverse effects after hospital discharge in multichronic patients: a randomized trial on transition of care intervention 15,50

Healthcare Delivery and Methodologies Geriatria Lazio € 450.000,00 € -

46RF-2018-12367938 CP

Liquid biopsy - Digging deep into tumor and host biology to refine breast cancer management 15,50


ISTITUTO TUMORI MILANO € 408.265,00 € -

47RF-2018-12368170 CP

Normothermic machine perfusion in split liver transplantation 15,50

Surgical Sciences, Biomedical Imaging, and Bioengineering Trapiantologia

OSPEDALE BAMBINO GESU' € 450.000,00 € -

48RF-2018-12366485 CP

Clinical and Neurobiological correlates of changes after Dialectical Behavioral Therapy in adolescents with Borderline Personality Disorder. A randomized clinical trial. 16,00

Brain Disorders and Clinical Neuroscience Malattie Psichiatriche FATEBENEFRATELLI € 448.525,00 € -

49RF-2018-12367899 CP

Whole Genome Sequencing-based tool to clinically patients with Nontuberculous mycobacteria pulmonary disease. 16,00

Infectious Diseases and Microbiology Malattie Infettive SAN RAFFAELE MILANO € 450.000,00 € -

50RF-2018-12367627 CP

IT'S TIME FOR ACTION: LOW-INFLAMMATORY DIET TO REDUCE INFLAMMATION AND IMPROVE QUALITY OF LIFE IN FAP PATIENTS 16,00

Risk, Prevention and Health Behavior Oncologia


51RF-2018-12367651 CP

A novel therapeutic option for disorders of consciousness: non-invasive thalamic neuromodulation using MRI-guided low-intensity focused ultrasound 16,00

Brain Disorders and Clinical Neuroscience Neurologia CARLO BESTA € 450.000,00 € -

6

BANDO 2018(fondo 2016-2017)


N. Code

Research

type Title

Voto finale


MOH IPOTESI


Finanziamento

52RF-2018-12365673 CP

Optimizing the management of lymphoma patients in the era of precision medicine: a prospective study using the liquid biopsy for disease outcome prediction and monitoring by quantitative assessment of clonotypic IGH rearrangement and circulating tumor DNA 16,00

Oncology 2 - Translational Clinical Ematologia e Immunologia HUMANITAS € 450.000,00 € -

53RF-2018-12365482 CP

The proactive role of Community-Hospital Platform in the Assessment and response to frailty in older subjects: the In (INRCA)PAR (PARma) CHO (CommunityHOspital) Study 16,00

Healthcare Delivery and Methodologies Geriatria Emilia-Romagna € 409.333,00 € -

54RF-2018-12366752 CP

Identification of a behavioral and fMRI predictive biomarker of clinical response to deep brain stimulation in drug-refractory obsessive compulsive tic disorder.

16,00Brain Disorders and Clinical Neuroscience Neurologia GALEAZZI € 247.800,00 € -

55RF-2018-12366929 CP

Adalimumab with and without Methotrexate in second step therapy for Juvenile Idiopathic Arthritis Uveitis: evidence of efficacy, safety and outcome predictors from a multi-centric observational prospective study 16,00

Musculoskeletal, Oral and Skin Sciences Pediatria Toscana € 445.221,00 € -

56RF-2018-12367832 CP

Inflammation and radiotherapy: friend or foe? A translational research to explain relationship and a possible way to optimize it. 16,50

Oncology 2 - Translational Clinical Oncologia Emilia-Romagna € 425.150,00 € -

57RF-2018-12366637 CP

A personalized translational approach for the PREvention and treatment of Surgical Site infections in patients Undergoing pancreatic REsection (PRESSURE) 16,50

Surgical Sciences, Biomedical Imaging, and Bioengineering Gastroenterologia HUMANITAS € 450.000,00 € -

58RF-2018-12367683 CP

Effects of aerobic training on motor and cognitive performances in patients with multiple sclerosis: a structural and functional MRI study 16,50

Brain Disorders and Clinical Neuroscience Neurologia SAN RAFFAELE MILANO € 450.000,00 € -

7

BANDO 2018(fondo 2016-2017)


N. Code

Research

type Title

Voto finale


MOH IPOTESI


Finanziamento

59RF-2018-12365494 CP

VIDEOMICROSCOPY VERSUS VIDEODERMATOSCOPY: A NON-INFERIORITY EVALUATION OF 2 SIMPLE NON-INVASIVE METHODS FOR THE DIAGNOSIS OF SCABIES. EFFICACY AND COST EFFECTIVENESS IN A MIGRANT POPULATION IN EASTERN SICILY

17,00Surgical Sciences, Biomedical Imaging, and Bioengineering Dermatologia Sicilia € 274.800,00 € -

60RF-2018-12365556 CP

BOTULINUM TOXINS HARBOURED BY NON-CLOSTRIDIAL ORGANISMS: RISK ASSESSMENT AND MITIGATION STRATEGIES 17,00 Veterinary Diagnostica

Istituto Superiore di Sanita' € 450.000,00 € -

61RF-2018-12365672 CP

Selective laser trabeculoplasty (SLT) for deprescribing maximal tolerated medical therapy in elderly and ultra-elderly glaucoma patients: evaluation of the rate of progression of visual field damage and quality of life 17,00

Brain Disorders and Clinical Neuroscience Oculistica BIETTI € 447.700,00 € -

62RF-2018-12366404 CP

Clinical impact of susceptibility mapping in brain MRI: from quantification to disease follow-up 17,00

Surgical Sciences, Biomedical Imaging, and Bioengineering Diagnostica STELLA MARIS € 450.000,00 € -

63RF-2018-12365250 CP

Prophylaxis of viral infections after haploidentical hematopoietic stem cell transplantation by adoptive T cell therapy with donor multivirus-specific T cells 17,00

Infectious Diseases and Microbiology Trapiantologia SAN MATTEO € 450.000,00 € -

64RF-2018-12365409 CP

Primary prevention of Neural Tube Defects by supplementation with folate plus inositol and genetic and metabolic profiling in high risk population 17,00

Risk, Prevention and Health Behavior Pediatria GASLINI € 437.000,00 € -

65RF-2018-12367951 CP

Effects of weight loss on cardiac remodelling: bariatric surgery versus intensive lifestyle modification. 17,00

Endocrinology, Metabolism, Nutrition and Reproductive Sciences Cardiologia-Pneumologia Friuli-Venezia Giulia € 450.000,00 € -

8

BANDO 2018(fondo 2016-2017)


N. Code

Research

type Title

Voto finale


MOH IPOTESI


Finanziamento

66RF-2018-12367937 CP

Unsolved challenges in congenital thyroid dysfunctions: definition of clinical and molecular predictors of cardiovascular risk.

17,00

Endocrinology, Metabolism, Nutrition and Reproductive Sciences Endocrinologia AUXOLOGICO € 383.500,00 € -

67RF-2018-12366380 CP

BI-UPCAT: BIlateral UPper-limb Children Action observation Training for children with diplegic cerebral palsy 17,00

Brain Disorders and Clinical Neuroscience Riabilitazione STELLA MARIS € 450.000,00 € -

68RF-2018-12366738 CP

Cardiac autonomic regulation over 24 hours, sleep homeostasis and systemic inflammation relationships in individuals following a three-shift schedule of work. 17,00

Cardiovascular and Respiratory Sciences Cardiologia-Pneumologia HUMANITAS € 450.000,00 € -

69RF-2018-12366277 CP

Novel biomarkers of thromboinflammation to stratify patients and guide treatments in systemic sclerosis. 17,00 Immunology Ematologia e Immunologia SAN RAFFAELE MILANO € 450.000,00 € -

70RF-2018-12367404 CP

CARDIOVASCULAR PREVENTION IN INFLAMMATORY SYSTEMIC DISORDERS: 'CUPID IS CALLING' PROGRAM 17,00

Musculoskeletal, Oral and Skin Sciences Ematologia e Immunologia Emilia-Romagna € 441.200,00 € -

71RF-2018-12366274 CP

Assessment of overuse and underuse of health care interventions in cancer care, and evaluation of the impact of delivering care through an innovative organisational model (clinical network) 17,00

Healthcare Delivery and Methodologies Oncologia

AUSL RE Ist. Tecnologie Avanzate € 420.000,00 € -

72RF-2018-12367373 CP

Evaluation of telemedicine for rare ocular and heart diseases 17,00 Genes, Genomes and Genetics Oculistica Campania € 438.000,00 € -

73RF-2018-12366074 CP

Impact of Mineralocorticoid Receptor pharmacological antagonism on arterial aging and metabolic parameters in overweight/obese middle age women women across menopausal transition: efficacy and pathophysiological mechanisms

17,50

Endocrinology, Metabolism, Nutrition and Reproductive Sciences Endocrinologia SAN RAFFAELE PISANA € 449.999,00 € -

9

BANDO 2018(fondo 2016-2017)


N. Code

Research

type Title

Voto finale


MOH IPOTESI


Finanziamento

74RF-2018-12365609 CP

Role of Vitamin K2 in association with local intraoperative therapy with diphosphonates to improve Bone Mineral Density (BMD) and femoral neck fracture healing in elderly Italian osteoporotic patients. 17,50

Musculoskeletal, Oral and Skin Sciences Ortopedia Abruzzo € 303.050,00 € -

75RF-2018-12367630 CP

Reducing the burden of radiologic contrast media-induced hypersensitivity reactions and the use of "anti-allergic" premedications: the COntrast MEdia CHAllenge (COMECHA) trial. 19,00 Immunology Ematologia e Immunologia Toscana € 409.000,00 € -

76RF-2018-12365770 CP

Safety and efficacy of dantrolene therapy in patients with acute ischemic stroke 19,00


77RF-2018-12366598 CP

Malaria detection in transfusion medicine: clinical and molecular strategies to optimise donors management and transfusion safety 19,00

Infectious Diseases and Microbiology Malattie Infettive Veneto € 398.410,00 € -

78RF-2018-12366386 CP

EFFICACY AND SAFETY OF LONG-TERM TREATMENT WITH ANTIRESORPTIVE AGENTS FOR OSTEOPOROSIS 20,50

Biology of Development and Aging Endocrinologia Sicilia € 448.400,00 € -

79RF-2018-12365595 CP

Environmental factors in the development and progression of essential tremor: new therapeutic approaches in a multidisciplinary study 20,50

Population Sciences and Epidemiology Neurologia SANTA LUCIA € 450.000,00 € -

80RF-2018-12367371 CP

HElmet NonInVasive ventilation versus high-flow Oxygen Therapy in acute hypoxemic respiratory failure: an open-label, multicentre randomized trial. The HENIVOT study 20,50

Cardiovascular and Respiratory Sciences Cardiologia-Pneumologia FONDAZIONE GEMELLI € 450.000,00 € -

81RF-2018-12366840 CP

Inflammatory profile of patients with severe asthma and chronic rhinosinusitis. Impact on disease control of inflammatory and metabolomic profiling. 17,50

Cardiovascular and Respiratory Sciences Cardiologia-Pneumologia MAUGERI € 333.400,00 € -

82RF-2018-12365694 CP

Diabetic Retinopathy screening by using an easy, portable and expert system smartphone-based 17,50

Emerging Technologies and Training in Neurosciences Oculistica BIETTI € 448.500,00 € -

10

BANDO 2018(fondo 2016-2017)


N. Code

Research

type Title

Voto finale


MOH IPOTESI


Finanziamento

83RF-2018-12365493 CP

Personalizing Care Using Routine Patient-Reported Symptom Monitoring During Cancer Treatment: a multicenter cluster randomized trial (CoSMo) 17,50

Risk, Prevention and Health Behavior Oncologia Emilia-Romagna € 446.510,00 € -

84RF-2018-12367215 CP

Integrated genomic and PET/MRI procedures for the characterization of breast cancer subtype: standardization of radiogenomic protocols and creation of an integrated open-access infrastructure 17,50

Surgical Sciences, Biomedical Imaging, and Bioengineering Diagnostica SDN € 400.000,00 € -

85RF-2018-12366871 CP

Development of Motor and Cognitive Reserve Index Tool for appropriateness and efficiency in Neurorehabilitation (DeMoCRIT Rehab) 17,50

Brain Disorders and Clinical Neuroscience Riabilitazione DON GNOCCHI € 303.240,00 € -

86RF-2018-12367730 CP

Immunological predictors of Healthy Aging: The observed progressive delay of frailty in adults living with HIV informs immunopathogenetic mechanism associated with Healthy Aging in the general population and allows to draw successful patient care models i 17,50 AIDS and Related Research Malattie Infettive Emilia-Romagna € 450.000,00 € -

87RF-2018-12367402 CP

Activity pacing monitoring in patients with fatigue symptoms through the combined use of portable electronic device and smartphone application 17,50

Risk, Prevention and Health Behavior Ematologia e Immunologia SAN RAFFAELE MILANO € 450.000,00 € -

88RF-2018-12367953 CP

Novel imaging and molecular biomarkers for assessing response to chemotherapy in advanced Gastric Cancer: development and validation of a multi-parametric predictive model to improve and optimize the patient management 17,50

Surgical Sciences, Biomedical Imaging, and Bioengineering Diagnostica Toscana € 390.000,00 € -

89RF-2018-12366760 CP

Biological age and work ability in the aging working force: effects of strenuous occupational conditions and of delayed retirement. 17,50

Population Sciences and Epidemiology Riabilitazione MAGGIORE € 439.000,00 € -

11

BANDO 2018(fondo 2016-2017)


N. Code

Research

type Title

Voto finale


MOH IPOTESI


Finanziamento

90RF-2018-12367702 CP

Definition of new key parameters for personalized care in Bone Fragility scenario 17,75

Musculoskeletal, Oral and Skin Sciences Riabilitazione RIZZOLI € 449.485,00 € -

91RF-2018-12368325 CP

Driving motor cortical oscillations for functional recovery in stroke patients: a tailored neuro-stimulation treatment 18,00

Brain Disorders and Clinical Neuroscience Neurologia SANTA LUCIA € 450.000,00 € -

92RF-2018-12367958 CP

Persistent Organic Pollutant (ß-HCH) contamination in Central Italy: biomonitoring, exposure assessment using Bayesian model and health effects evaluation in a large cohort of residents 18,00

Population Sciences and Epidemiology Diagnostica Lazio € 450.000,00 € -

93RF-2018-12366331 CP

Early albumin administration in patients with decompensated cirrhosis hospitalized for non-SBP infections: a factor VIII-guided approach to improve the intra-hospital outcome. 18,00

Digestive, Kidney and Urological Systems Gastroenterologia MAGGIORE € 445.000,00 € -

94RF-2018-12365792 CP

Validation of sarcolipin as an early biomarker in ALS patients 18,00


95RF-2018-12365106 CP

Behavioral and neural effects of repeated noninvasive brain stimulation in older adults with subjective memory complaints 18,00

Biobehavioral and Behavioral Processes Geriatria FATEBENEFRATELLI € 440.265,00 € -

96RF-2018-12365127 CP

The role of vitamin D binding protein in multiple sclerosis: a prospective longitudinal study in newly diagnosed patients 18,00 Immunology Neurologia


97RF-2018-12365873 CP

An integromic approach based on genotype-related inflammatory and oxidative profiling and wearable-health technology for personalized therapy in Parkinson's disease 18,00


98RF-2018-12365153 CP

Red orange juice daily consumption and human health: a pilot study in high cardio-metabolicrisk subjects and Type 2 Diabetic patients 18,00

Endocrinology, Metabolism, Nutrition and Reproductive Sciences Endocrinologia


12

BANDO 2018(fondo 2016-2017)


N. Code

Research

type Title

Voto finale


MOH IPOTESI


Finanziamento

99RF-2018-12367863 CP

Predicting multiple organ specific autoimmunity in childhood: development and optimization of a screening strategy for autoimmune co-morbidities in pediatric patients. 18,00 Immunology Pediatria SAN RAFFAELE MILANO € 450.000,00 € -

100RF-2018-12367443 CP

Magnetic Resonance guided Focused UltraSound (MRgFUS) versus Levodopa/Carbidopa Intestinal Gel (LCIG) in patients with asymmetric Parkinson's disease 18,50


101RF-2018-12365732 CP

Validating the histaminergic receptors and enzymes as biomarkers in relapsing-remitting and progressive multiple sclerosis and testing the anti-inflammatory power of histamine in innate immune cells from patients 18,50


102RF-2018-12367418 CP

Searching for morpho-functional and genetic biomarkers of the clinical disability related to the visual disturbances of migraine with aura patients 18,50

Brain Disorders and Clinical Neuroscience Neurologia BIETTI € 450.000,00 € -

103RF-2018-12367270 CP

The bovine biological signature: a holistic approach to strengthen steroid abuse monitoring 18,50 Veterinary Diagnostica IZSPLV € 450.000,00 € -

104RF-2018-12368261 CP

Applying REal-time Sequencing for foodborne pathogens in Italy- Acronym - ARES

18,50 Veterinary Malattie Infettive IZSAM € 411.115,00 € -

105RF-2018-12367428 CP

Kinematic assessment of cervical dystonia: phenomenology and response to treatment 18,50

Brain Disorders and Clinical Neuroscience Neurologia HUMANITAS € 447.500,00 € -

106RF-2018-12366978 CP

Focus on HIV-1 subjects with a multidrug resistant virus and limited antiretroviral options (Prestigio Registry) 18,50 AIDS and Related Research Malattie Infettive SAN RAFFAELE MILANO € 450.000,00 € -

13

BANDO 2018(fondo 2016-2017)


N. Code

Research

type Title

Voto finale


MOH IPOTESI


Finanziamento

107RF-2018-12367152 CP

Advanced therapy medicinal product based on mutated NPM1-specific cytotoxic T cells for the treatment of patients with relapsed/refractory NPM1-mutated acute myeloid leukemia 18,50

Oncology 2 - Translational Clinical Ematologia e Immunologia SAN MATTEO € 450.000,00 € -

108RF-2018-12368075 CP

Tackling UnderRecognized Mood disOrders to Improve Long-term Chronic Coronary Care (TURMOIL-CCC) 18,50

Risk, Prevention and Health Behavior Riabilitazione DON GNOCCHI € 279.942,00 € -

109RF-2018-12368224 CP

Addressing challenges in the chronic Hepatitis C Infection cascade of care to achieve the WHO elimination goals. Identification of possible strategies able to increase the diagnosis, linkage to care and access to antiviral therapy. Translation of modellin 18,50

Healthcare Delivery and Methodologies Malattie Infettive


110RF-2018-12367194 CP

The role of circulating Micro-RNAs profile in patients with severe aortic stenosis following transcatheter aortic valve intervention. MIRN TAVI Study 18,50

Cardiovascular and Respiratory Sciences Cardiologia-Pneumologia SAN RAFFAELE MILANO € 450.000,00 € -

111RF-2018-12366936 CP

Extensive molecular profiling of radically resected colon cancer patients enrolled in the phase 3 randomized TOSCA trial onadjuvant treatment duration - The TATA (TOSCA Adjuvant Translational Analysis) project 18,50

Oncology 2 - Translational Clinical Oncologia I. O. V. € 450.000,00 € -

112RF-2018-12365727 CP

An integrated and multidisciplinary approach for the treatment of substance use disorder 19,00

Biobehavioral and Behavioral Processes Malattie Psichiatriche SANTA LUCIA € 449.700,00 € -

113RF-2018-12368360 CP

Hazards and risks of heart disease related to epilepsy and anti-epileptic drugs, unmasked by exhaustive neurophysiologic and cardiologic investigations: a prospective, advanced diagnostic evaluation that can identify early potentially fatal cardiac abnorm 19,00

Brain Disorders and Clinical Neuroscience Neurologia Calabria € 220.000,00 € -

14

BANDO 2018(fondo 2016-2017)


N. Code

Research

type Title

Voto finale


MOH IPOTESI


Finanziamento

114RF-2018-12368158 CP

Whole exome sequencing to decipher the basis of insulin-dependent diabetes mellitus and rheumatoid arthritis in autoantibody-negative patients 19,00 Genes, Genomes and Genetics Ematologia e Immunologia SAN RAFFAELE MILANO € 450.000,00 € -

115RF-2018-12367763 CP

Intra-cardiac fluid-dynamic pattern and morphofunctional characteristics in patients with post-ischemic and primitive dilated cardiomyopathy to predict clinical outcome and left ventricle remodeling. MICROPHONE_study 19,00

Cardiovascular and Respiratory Sciences Cardiologia-Pneumologia SAN DONATO € 420.100,00 € -

116RF-2018-12367535 CP

Reliable biomarkers, pathogenic mechanisms and effects of therapy in Fabry Disease 19,50

Brain Disorders and Clinical Neuroscience Neurologia

Istituto Scienze Neurologiche € 450.000,00 € -

117RF-2018-12368006 CP

Identification of noninvasive biomarkers in H3-K27M mutant midline gliomas such as diffuse intrinsic pontine glioma 19,50

Oncology 2 - Translational Clinical Pediatria


118RF-2018-12367246 CP

Providing effective treatment and overcoming Resistance with tailOred Treatment of sEvere baCterial infections in hospiTalised patientsPROTECT

19,50Infectious Diseases and Microbiology Malattie Infettive Veneto € 450.000,00 € -

119RF-2018-12365757 CP

Spinal Cord Injury: study of the activation of the innate immune system for the identification of patients with good or low recovery. 19,50


120RF-2018-12367105 CP

ATTENTION AND PERFORMANCE: AN ICT NEUROPSYCHOLOGICAL ASSESSMENT ACROSS THE LIFE SPAN 19,50

Integrative, Functional, and Cognitive Neuroscience Neurologia AUXOLOGICO € 450.000,00 € -

121RF-2018-12366276 CP

Perioperative steroids schema for the prevention of major complications after pancreaticoduodenectomy in patients at high-risk for pancreatic fistula: a randomized controlled trial

19,50Surgical Sciences, Biomedical Imaging, and Bioengineering Oncologia Veneto € 150.000,00 € -

15

BANDO 2018(fondo 2016-2017)


N. Code

Research

type Title

Voto finale


MOH IPOTESI


Finanziamento

122RF-2018-12368227 CP

Clinical impact and neurophysiological implications of a goal-based exercise in Parkinson Disease: a randomized controlled trial. 20,00

Biobehavioral and Behavioral Processes Riabilitazione Toscana € 440.000,00 € -

123RF-2018-12365582 CP

Identification of somatic mosaicism in patients with epileptogenic developmental disorders (EDD): implementing the diagnostic workflow in the next-generation sequencing era 20,00

Brain Disorders and Clinical Neuroscience Neurologia Toscana € 301.365,00 € -

124RF-2018-12368188 CP

Sequential targeted therapy and immunotherapy in symptomatic melanoma brain metastases: a phase 2 randomised trial 20,00

Oncology 2 - Translational Clinical Oncologia Toscana € 448.500,00 € -

125RF-2018-12365572 CP

Improving predictors of global outcome and treatment response in mild cognitive impairment subjects with Parkinson's Disease: A single-blind case-control randomized longitudinal study comparing cognitive stimulation alone to an augmented experimental mul 20,00


126RF-2018-12367836 CP

PLASMA-LYTE VS NORMAL SALINE TRIAL IN INTENSIVE CARE (PlaSTIC Study) 20,00

Surgical Sciences, Biomedical Imaging, and Bioengineering Cardiologia-Pneumologia HUMANITAS € 450.000,00 € -

127RF-2018-12367379 CP

Post-surgical scars: a clinical and objective diagnostic criteria for pathologic adherent scars, and effectiveness of manual treatment on patient-reported, clinical, and functional outcome measures 20,25

Musculoskeletal, Oral and Skin Sciences Riabilitazione MAUGERI € 365.280,00 € -

128RF-2018-12367982 CP

Cerebrospinal fluid HIV-1 viral escape: clinical consequences, nature of viral persistence and characterization of neuroinflammatory profile in a longitudinally studied HIV-infected ART-treated population 20,25 AIDS and Related Research Malattie Infettive SPALLANZANI € 440.000,00 € -

16

BANDO 2018(fondo 2016-2017)


N. Code

Research

type Title

Voto finale


MOH IPOTESI


Finanziamento

129RF-2018-12366803 CP

A pragmatic phase-IV clinical trial comparing the effectiveness of two different compounds (Amitriptyline and Venlafaxine) for the prophylaxis of chronic tension-type headache: addressing the role of peripheral biomarkers and gut microbiota. 20,25

Emerging Technologies and Training in Neurosciences Neurologia CARLO BESTA € 355.471,70 € -

130RF-2018-12368307 CP

Tailored screening strategies for subjects at increased risk of neoplasia based on the cumulative fecal Haemoglobin level at previous tests. A randomized trial in a screening setting 20,50

Population Sciences and Epidemiology Oncologia Piemonte € 446.700,00 € -

131RF-2018-12368122 CP

Preserving autonomy in everyday life and enhancing resilience: optimization of residual visual and motor functions in patients with retinopathy and diabetic neuropathy for the reduction of falls and plantar ulcers, through evaluation of metabolic markers, 20,50

Musculoskeletal, Oral and Skin Sciences Endocrinologia


132RF-2018-12367118 CP

Do Antidiabetic Drugs Protect or Induce Parkinson¿ds Disease? A Population-based Study in Umbria. 20,50

Population Sciences and Epidemiology Neurologia Umbria € 399.500,00 € -

133RF-2018-12365702 CP

LYSOSOMAL ACID LIPASE: TOWARDS A NEW AND SENSITIVE BIOMARKER OF SEVERITY IN NON-ALCOHOLIC FATTY LIVER DISEASE 20,50

Digestive, Kidney and Urological Systems Gastroenterologia Lazio € 426.850,00 € -

134RF-2018-12365434 CP

SMARTBAR - SMART tools for the effectiveness assessment and the optimization of procedures in BARiatric surgery 20,50

Surgical Sciences, Biomedical Imaging, and Bioengineering Gastroenterologia Veneto € 443.440,00 € -

135RF-2018-12367191 CP

Improving the Safety and Efficacy of Gene Transfer and Hematopoietic Stem Cell Expansion Technologies 20,50 Vascular and Hematology Ematologia e Immunologia SAN RAFFAELE MILANO € 450.000,00 € -

17

BANDO 2018(fondo 2016-2017)


N. Code

Research

type Title

Voto finale


MOH IPOTESI


Finanziamento

136RF-2018-12367421 CP

Analysis of combined assessment of metabolic radiomics pattern in [18]F-FDG PET/CT, Immunogenic Cell Death induction and microbiota in the prediction of response to neoadjuvant chemotherapy in breast cancer patients. 20,50

Oncology 2 - Translational Clinical Oncologia HUMANITAS € 450.000,00 € -

137RF-2018-12368042 CP

Occurrence of Fusarium mycotoxins and their metabolites in cereals grains: development of comprehensive studies to understand the role of emerging mycotoxins in the human and animal food chain. 20,50 Veterinary Gastroenterologia IZSSI € 390.000,00 € -

138RF-2018-12367099 CP

Retuning network dynamics in Obsessive Compulsive Tic Disorders: safety and efficacy of personalized adaptive Deep Brain Stimulation. 20,50

Brain Disorders and Clinical Neuroscience Neurologia Lombardia € 430.000,00 € -

139RF-2018-12367757 CP

Use of antipyschotic drugs in dementia: a multicenter pharmacoepidemiological study in current clinical practice 20,50

Population Sciences and Epidemiology Neurologia Lazio € 350.000,00 € -

140RF-2018-12367666 CP

Experimental methods for comparative evaluation of Welfare in 'effective protection orphans animals (EPOA)' that are used for non-zootechnical purposes: animal experimentation, animals-assisted therapy (AAT) and dogs kept in kennels. 20,50 Veterinary Diagnostica


141RF-2018-12368234 CP

Universal cervical length screening in low risk general population at second trimester: impact on preterm birth rate and cost-effectiveness analysis. 20,50

Endocrinology, Metabolism, Nutrition and Reproductive Sciences Ostetricia e Ginecologia Emilia-Romagna € 190.200,00 € -

142RF-2018-12367451 CP

Efficacy of inhaled GM-CSF in the treatment of Autoimmune Pulmonary Alveolar Proteinosis. 21,00

Cardiovascular and Respiratory Sciences Cardiologia-Pneumologia SAN MATTEO € 450.000,00 € -

18

BANDO 2018(fondo 2016-2017)


N. Code

Research

type Title

Voto finale


MOH IPOTESI


Finanziamento

143RF-2018-12365558 CP

Insights into predictors of incidence and prognosis of HIV-related malignancies: role of clinical and tumor microenvironment related factors with focus on plasma derived exosomes 21,00 AIDS and Related Research Oncologia SPALLANZANI € 448.100,00 € -

144RF-2018-12368161 CP

Assessing the efficacy of the Informed Health Choices Learning-program to improve health literacy and informed choices in Italian primary school children: a randomised controlled trial 21,00

Healthcare Delivery and Methodologies Pediatria MARIO NEGRI € 380.500,00 € -

145RF-2018-12366476 CP

The addition of aerobic training to conventional rehabilitation after proximal femur fracture: analysis of the effects on growth factor and clinical symptoms. 21,00

Musculoskeletal, Oral and Skin Sciences Riabilitazione MAUGERI € 298.000,00 € -

146RF-2018-12366473 CP

Personalized Intervention Model in a Multidomain COPD Rehabilitation Framework 21,00

Healthcare Delivery and Methodologies Riabilitazione SAN RAFFAELE PISANA € 446.350,00 € -

147RF-2018-12365640 CP

Development of innovative mucoadhesive platforms for topical delivery of chemopreventive drugs in oral potentially malignant disorders 21,00

Bioengineering Sciences and Technologies Otorinolaringoiatria e Odontoiatria


148RF-2018-12367292 CP

Multidisciplinary approach in high grade glioma 21,00

Oncology 2 - Translational Clinical Oncologia I.E.O. € 446.000,00 € -

149RF-2018-12367957 CP

Air pollution, occupational exposure, socioeconomic position and incidence of neurodegenerative diseases in two large cohort studies 21,00

Population Sciences and Epidemiology Neurologia Lazio € 350.015,00 € -

150RF-2018-12368312 CP

Revisiting the role of rapamycin and tacrolimus (FK506) to develop novel treatments for iron, erythrocyte and metabolic disorders 21,00 Vascular and Hematology Ematologia e Immunologia SAN RAFFAELE MILANO € 450.000,00 € -

19

BANDO 2018(fondo 2016-2017)


N. Code

Research

type Title

Voto finale


MOH IPOTESI


Finanziamento

151RF-2018-12365996 CP

Metacognition and anosognosia in early clinical neurodegenerative dementias (Alzheimer and Parkinson diseases) as predictors of cognitive outcome: a multidisciplinary study of pathogenic correlates, neuroimaging markers and rehabilitative treatment. 21,00


152RF-2018-12367557 CP

Deprescription of sulfonylureas in advanced age 21,00

Endocrinology, Metabolism, Nutrition and Reproductive Sciences Endocrinologia Toscana € 276.000,00 € -

153RF-2018-12367274 CP

Promoting healthy lifestyles and psychological well-being in patients with common mental disorders

21,50Biobehavioral and Behavioral Processes Malattie Psichiatriche Emilia-Romagna € 400.000,00 € -

154RF-2018-12368163 CP

LCAT as a novel target in the acute coronary syndrome: focus on vasoprotective effects of HDL 21,50

Cardiovascular and Respiratory Sciences Cardiologia-Pneumologia Lombardia € 450.000,00 € -

155RF-2018-12365799 CP

Responsiveness to noxious stimuli in non-communicative survivors after severe Acquired Brain Injury: longitudinal clinical and neurophysiology study with Pressure Pain Threshold Test, Laser-Evoked Potentials and Polysomnography to provide an objective par 21,50


156RF-2018-12367326 CP

Discovery of novel biomarkers for the early diagnosis and prognostic stratification of patients with malignant pleural mesothelioma 21,50


157RF-2018-12366763 CP

Novel immunotherapeutic approach in Type 1 diabetes and autoimmune polyendocrine syndrome Type 3 variant: use of immunoliposome-delivered siRNA duplex to PTPN22 C1858T gene polymorphism 21,50 Immunology Endocrinologia


20

BANDO 2018(fondo 2016-2017)


N. Code

Research

type Title

Voto finale


MOH IPOTESI


Finanziamento

158RF-2018-12365816 CP

Targeting the host tyrosine kinases to improve the efficacy of current antimalarial combination therapies and to fight emerging artemisinin resistance. 21,50

Infectious Diseases and Microbiology Malattie Infettive


159RF-2018-12367677 CP

Contribution of brain amylOid and autoNomic dysfunction to coGnitive impairment in Parkinson disEase and roLe of cognitive training and neuromodulation: The CONGEAL study 21,50

Brain Disorders and Clinical Neuroscience Neurologia Veneto € 424.610,00 € -

160RF-2018-12367367 CP

Focal and multilobar dysplasia of the cerebral cortex: effectiveness of molecular testing to optimize epilepsy surgery strategies and personalizing pharmacological treatments 21,50

Brain Disorders and Clinical Neuroscience Neurologia Toscana € 443.716,20 € -

161RF-2018-12365962 CP

Heart failure and subclinical cardiovascular dysfunction in type 2 diabetes: understanding new targets for treatment 21,50

Cardiovascular and Respiratory Sciences Cardiologia-Pneumologia Toscana € 450.000,00 € -

162RF-2018-12365261 CP

Developing a liquid biopsy tool (Lb) for Hereditary Papillary Carcinoma of Renal Cells (HPRCC) Syndrome 22,00


163RF-2018-12366157 CP

Theory Of Mind enhancement in MYotonic dystrophy type 1 (TOMMY): Neuroimaging and neurophysiological assessment for improving neuroplasticity in a personalized motor and cognitive rehabilitation 22,00


164RF-2018-12367293 CP

Effect of an integrated levodopa low dose plus high-intensity treadmill exercise protocol vs levodopa low dose alone on motor symptoms in patients with early Parkinson's disease: a randomized parallel group controlled trial 22,00

Brain Disorders and Clinical Neuroscience Neurologia


21

BANDO 2018(fondo 2016-2017)


N. Code

Research

type Title

Voto finale


MOH IPOTESI


Finanziamento

165RF-2018-12366690 CP

TemaRep: Technological assessment of EEG networks and biomechanical Motor activity in Acute stroke for Recovery Prognosis 22,00

Brain Disorders and Clinical Neuroscience Neurologia FONDAZIONE GEMELLI € 430.000,00 € -

166RF-2018-12366177 CP

Comprehensive neurophysiological assessment in severe acquired brain injury to enable binary-coded communication by means of a EEG-based Brain-Computer Interface (BCI). 22,00

Brain Disorders and Clinical Neuroscience Riabilitazione SANTA LUCIA € 372.556,00 € -

167RF-2018-12368142 CP

Double blind randomized controlled placebo trial with oral tetrabenazine vs trihexyphenidyl in children affected by dyskinetic cerebral palsy 22,00

Brain Disorders and Clinical Neuroscience Neurologia STELLA MARIS € 342.000,00 € -

168RF-2018-12365505 CP

OPENING NEW THERAPEUTIC HORIZONS IN INFLAMMATORY BOWEL DISEASE: EFFICACY AND COST-EFFECTIVENESS OF THE MEDITERRANEAN EXCLUSION DIET IN MAINTAINING REMISSION OF PEDIATRIC AND ADULT PATIENTS WITH CROHN'S DISEASE 22,00

Digestive, Kidney and Urological Systems Gastroenterologia Lazio € 424.000,00 € -

169RF-2018-12367504 CP

ASSESSING MKK3 AS A NOVEL PROGNOSTIC MARKER AND THERAPEUTIC TOOL IN COLORECTAL CANCER 22,00 Oncology 1 - Basic Translational Oncologia REGINA ELENA € 450.000,00 € -

170RF-2018-12366243 CP

The effect of combined physical activity program and cognitive training on quality of life of elderly patients with prostate cancer treated with androgen deprivation therapy: a clinical randomized study

22,00Biobehavioral and Behavioral Processes Geriatria Veneto € 440.000,00 € -

171RF-2018-12367366 CP

Identification of circulating biomarkers and imaging techniques able to detect nonalcoholic steatohepatitis (NASH) and early cardiovascular damage in patients with type 2 diabetes 22,00

Endocrinology, Metabolism, Nutrition and Reproductive Sciences Gastroenterologia MAGGIORE € 450.000,00 € -

22

BANDO 2018(fondo 2016-2017)


N. Code

Research

type Title

Voto finale


MOH IPOTESI


Finanziamento

172RF-2018-12366395 CP

Pancreatic cancer molecular sub-classification for prognostic stratification and individualized therapy using endoscopic ultrasound tissue core biopsy samples. 22,00

Oncology 2 - Translational Clinical Oncologia FONDAZIONE GEMELLI € 426.860,00 € -

173RF-2018-12365877 CP

Soluble RAGE isoforms as biomarkers of cardiac remodeling affected by aging: are they responsive to body composition changes mediated by dietary intervention? 22,00

Biology of Development and Aging Geriatria MONZINO € 449.900,00 € -

174RF-2018-12365668 CP

INNOVATIVE PROCEDURES TO FIGHT HBV, HCV AND HIV INFECTION IN A HIGH-RISK POPULATION OF UNDOCUMENTED MIGRANTS AND REFUGEES 22,00

Infectious Diseases and Microbiology Malattie Infettive Campania € 450.000,00 € -

175RF-2018-12366841 CP

Work And Cancer (WAC): smart assistance to support cancer survivors in the labor environment 22,00

Healthcare Delivery and Methodologies Oncologia Piemonte € 450.000,00 € -

176RF-2018-12366524 CP

Integrated multidisciplinary care for chronic neurological disorders in the Community Health Centres (Case della Salute): analysis and impact on healthcare quality in the Local Health Trust of Bologna.Short Title: Integrated MUltidisciplinary CAre for ch 22,00

Healthcare Delivery and Methodologies Neurologia


177RF-2018-12367091 CP

Comparison between a short versus a standard dual antiplatelet treatment duration in elderly patients with acute coronary syndromes at high risk of bleeding: the Elderly ACS High Bleeding Risk Study. 22,00

Cardiovascular and Respiratory Sciences Cardiologia-Pneumologia MULTIMEDICA € 450.000,00 € -

178RF-2018-12365803 CP

Web-based Motherhood choice decision aid for women with Multiple Sclerosis (We-MoMS): Intervention development and testing 22,50


23

BANDO 2018(fondo 2016-2017)


N. Code

Research

type Title

Voto finale


MOH IPOTESI


Finanziamento

179RF-2018-12365693 CP

A randomized clinical trial to personalise treatment with 223-Radium of bone metastases in metastatic castration resistant prostate cancer patients (project acronym: RATAPLAN - RAdium TherApy PersonaLized treAtmeNt) 22,50

Oncology 2 - Translational Clinical Oncologia REGINA ELENA € 446.520,00 € -

180RF-2018-12365452 CP

Effects of Colchicine in patients with ST-elevation Myocardial infarction undergoing Primary Percutaneous Coronary Intervention: a randomised clinical trial.

26,00Cardiovascular and Respiratory Sciences Cardiologia-Pneumologia HUMANITAS € 450.000,00 € -

181RF-2018-12366205 CP

Phenotyping the procoagulant pattern in obstructive sleep apnea: a pathway towards prevention of thromboembolic events 26,00

Cardiovascular and Respiratory Sciences Cardiologia-Pneumologia SAN DONATO € 414.575,00 € -

182RF-2018-12367180 CP

Clinical and Imaging outcome of focal osteochondRal lesiOns treated usiNg UMbilical Cord Blood Platelet DerivAtives aNd a biomimetic scaffold (IRONMAN) 22,50

Surgical Sciences, Biomedical Imaging, and Bioengineering Ortopedia Toscana € 450.000,00 € -

183RF-2018-12368061 CP

In-patient vs. out-patient rehabilitation in Parkinson¿s disease and multiple sclerosis: indications, cost-effectiveness, and effects on satisfaction and quality of life. 22,50

Brain Disorders and Clinical Neuroscience Neurologia DON GNOCCHI € 315.400,00 € -

184RF-2018-12365655 CP

FLUORESCENCE CONFOCAL MICROSCOPY FOR RAPID BED-SIDE PATHOLOGY IN SURGICAL ONCOLOGY: SKIN, BREAST AND PROSTATE CANCER 22,50

Surgical Sciences, Biomedical Imaging, and Bioengineering Diagnostica


185RF-2018-12365453 CP

SHAPING THE EVOLUTION OF TAU-RELATED BRAIN DYSFUNCTION IN ALZHEIMER'S DISEASE (SHAPEAD): A NOVEL MULTIMODAL APPROACH TO PREDICT DISEASE PROGRESSION.

22,50Brain Disorders and Clinical Neuroscience Neurologia SANTA LUCIA € 450.000,00 € -

24

BANDO 2018(fondo 2016-2017)


N. Code

Research

type Title

Voto finale


MOH IPOTESI


Finanziamento

186RF-2018-12366915 CP

A prospective study, experimental and observational, aimed at refining the risk-benefit ratio and defining actual indications of active surveillance in low risk papillary thyroid microcarcinoma (PTMC). Differential assessment of quality of life and advers 23,00

Endocrinology, Metabolism, Nutrition and Reproductive Sciences Endocrinologia PASCALE € 450.000,00 € -

187RF-2018-12365400 CP

The use of classical conditioning with a telemedicine approach in chronic aphasia patients with and without associated cognitive deficits 23,00

Brain Disorders and Clinical Neuroscience Riabilitazione SANTA LUCIA € 200.000,00 € -

188RF-2018-12366343 CP

DAFNE: Deciphering Autistic Females through Neuroimaging and Exome 23,00

Brain Disorders and Clinical Neuroscience Malattie Psichiatriche STELLA MARIS € 450.000,00 € -

189RF-2018-12367457 CP

The MATRIx (MesenchymAl Traumatic bRain Injury) study: a phase I/II clinical trial of intravenous allogeneic mesenchymal stromal cells for traumatic brain injury 23,00

Brain Disorders and Clinical Neuroscience Neurologia MARIO NEGRI € 450.000,00 € -

190RF-2018-12366489 CP

Hereditary neurodegenerative ataxias: a paradigm for developing and testing an innovative model of integrated care and clinical research management in rare neurological diseases 23,00


191RF-2018-12365370 CP

Exposure characterization and evaluation of adverse biological effects of nanomaterials in the occupational setting (NANOWORK) 23,00

Population Sciences and Epidemiology Oncologia SAN RAFFAELE PISANA € 450.000,00 € -

192RF-2018-12367952 CP

Altered fatty acid metabolism in diffuse malignant peritoneal mesothelioma as source for new biomarkers and therapeutic targets 23,00



25

BANDO 2018(fondo 2016-2017)


N. Code

Research

type Title

Voto finale


MOH IPOTESI


Finanziamento

193RF-2018-12367544 CP

Amyotrophic Lateral Sclerosis (ALS): characterizing disease phenotype and patients' preferences to optimize ALS care pathway in Italy - I-CP-ALS 23,00

Healthcare Delivery and Methodologies Neurologia Emilia-Romagna € 306.470,00 € -

194RF-2018-12367642 CP

Prognostic relevance of coagulation Activation in RIsk Assessment and Stratification in reference to patient important outcomes for locally advanced breast cancer: the ARIAS trial. 23,00


195RF-2018-12368181 CP

A phase I clinical trial of intratumoral administration of interferon-dendritic cells in combination with chemoradiotherapy in glioblastoma patients 23,00



196RF-2018-12367412 CP

Optimizing pre- and post- total knee arthroplasty pain control by opioid tailored therapy, using Lymphocyte opioid receptors as innovative biomarkers to prevent chronic pain and opioid tolerance/addiction development 23,00

Surgical Sciences, Biomedical Imaging, and Bioengineering Ortopedia Lazio € 450.000,00 € -

197RF-2018-12366858 CP

Towards self-administered, home-based motor rehabilitation in Parkinson's disease: development and clinical application of a new wearable Smartphone-based biofeedback system for balance and gait training 23,00

Musculoskeletal, Oral and Skin Sciences Riabilitazione DON GNOCCHI € 431.500,00 € -

198RF-2018-12368391 CP

A research study to understand, improve and develop a patient centered care adherence strategy in systemic lupus erythematosus (SLE) in Italy. An Integrated patient-physician care protocol. 23,00

Musculoskeletal, Oral and Skin Sciences Ematologia e Immunologia Toscana € 279.000,00 € -

199RF-2018-12368371 CP

Long-term post-natal follow up of brain malformations detected with fetal MRI: a clinical, genetic, and imaging study in a large cohort. 23,50

Brain Disorders and Clinical Neuroscience Neurologia MEDEA € 444.510,00 € -

26

BANDO 2018(fondo 2016-2017)


N. Code

Research

type Title

Voto finale


MOH IPOTESI


Finanziamento

200RF-2018-12367169 CP

Chest Magnetic Resonance Imaging (MRI) and innovative peripheral markers for evaluating early response to old and novel therapy in patients with interstitial lung diseases 23,50

Cardiovascular and Respiratory Sciences Diagnostica Toscana € 400.000,00 € -

201RF-2018-12365643 CP

INFECTIOUS MONONUCLEOSIS AND RISK OF AUTOIMMUNITY: A CLINICAL, EPIDEMIOLOGICAL AND BIOCHEMICAL STUDY 23,50

Infectious Diseases and Microbiology Malattie Infettive


202RF-2018-12366256 CP

Effects of Direct-acting agents (DAA) anti- HCV therapy on HIV virological and immunological outcome in ART-suppressed HIV/HCV co-infected patients and impact of gender 23,50 AIDS and Related Research Malattie Infettive


203RF-2018-12367911 CP

Field-Practice study of regorafenib therapy for hepatocellular carcinoma 23,50

Oncology 2 - Translational Clinical Gastroenterologia Sicilia € 444.888,00 € -

204RF-2018-12367907 CP

Short and long-term effects of environmental exposure (air pollution and temperature) and lifestyle on cardiovascular events. Merging satellite observations with the EPIC Italian cohorts: the EPICOR-AIR study 23,50

Population Sciences and Epidemiology Cardiologia-Pneumologia Lazio € 450.000,00 € -

205RF-2018-12365417 CP

Markers of Infection in Suspected Sepsis (MISS Study) 23,50

Infectious Diseases and Microbiology Malattie Infettive Sicilia € 447.500,00 € -

206RF-2018-12366281 CP

Implementing liquid biopsy as a key decisional tool for therapeutic management of patients with Non Small Cell Lung Cancer. 23,50

Oncology 2 - Translational Clinical Oncologia C.R.O. AVIANO € 450.000,00 € -

207RF-2018-12366494 CP

Tranexamic Acid to reduce the number of patients receiving red blood cells transfusions in non cardiac surgery: a randomized controlled trial. 23,50

Surgical Sciences, Biomedical Imaging, and Bioengineering Cardiologia-Pneumologia GALEAZZI € 450.000,00 € -

208RF-2018-12367382 CP

Comparing and Reducing Variation: Individual Data Collection and Verification for Big Data Applications in Radiotherapy 23,50


209RF-2018-12367733 CP

OLEUROPEIN FOR TREATMENT OF ULCERATIVE COLITIS 24,00

Digestive, Kidney and Urological Systems Gastroenterologia Calabria € 450.000,00 € -

27

BANDO 2018(fondo 2016-2017)


N. Code

Research

type Title

Voto finale


MOH IPOTESI


Finanziamento

210RF-2018-12366606 CP

Association of the non-coding RNA signature with cardiac computed tomography phenotype in coronary artery disease: an integrated epigenetic and radiomic approach 24,00

Cardiovascular and Respiratory Sciences Cardiologia-Pneumologia SDN € 450.000,00 € -

211RF-2018-12366039 CP

A gender approach in Rheumatoid Arthritis management: identification and validation of sex-specific predictive biomarkers in patients treated with TNF-inhibiting drugs 24,00 Immunology Ematologia e Immunologia


212RF-2018-12367171 CP

Targeting the epi-transcriptome as a novel therapeutic approach for the treatment of Duchenne Muscular Dystrophy 24,00

Musculoskeletal, Oral and Skin Sciences Neurologia SANTA LUCIA € 450.000,00 € -

213RF-2018-12368276 CP

Dysphagia in the different stages of Huntington disease: characteristics, multidisciplinary management and potential innovative treatment from the early up to the advanced phases 24,00

Biobehavioral and Behavioral Processes Riabilitazione Lombardia € 450.000,00 € -

214RF-2018-12367164 CP

Improvement of the management of patients bearing non-invasive breast cancer (DCIS):identification of miRNAs as prognosticators of low-risk for malignant evolution and use ofretinoids for their up-regulation as prevention/protective strategy 24,00


215RF-2018-12367800 CP

Characteristics and outcomes of transition from pediatric to adult care for adolescents with chronic health needs in Italy 24,00

Healthcare Delivery and Methodologies Pediatria MARIO NEGRI € 450.000,00 € -

28

BANDO 2018(fondo 2016-2017)


N. Code

Research

type Title

Voto finale


MOH IPOTESI


Finanziamento

216RF-2018-12365664 CP

Adherence, safety and impact of pharmacogenetics of lipid lowering therapy: proprotein convertase subtilisin/kexin 9 inhibitors plus statins/ezetimibe vs statins/ezetimibe in high cardiovascular risk patients. An observational study. 24,00

Cardiovascular and Respiratory Sciences Cardiologia-Pneumologia Campania € 450.000,00 € -

217RF-2018-12368208 CP

Dissecting the pathogenesis of human skeletal muscle wasting in liver transplant recipients and the molecular mechanisms behind its possible reversibility: Multicentric Prognostic Cohort Study 24,00

Musculoskeletal, Oral and Skin Sciences Trapiantologia ISMETT € 436.550,00 € -

218RF-2018-12368363 CP

Computational-based Adaptive virtual Reality training for Autism (CARA) 24,00

Healthcare Delivery and Methodologies Malattie Psichiatriche AUXOLOGICO € 436.000,00 € -

219RF-2018-12368372 CP

Decision-making algorithms to enhance the quality of care in Emergency Neurology ¿ Transient loss of consciousness and seizure 24,50

Healthcare Delivery and Methodologies Neurologia MONDINO € 169.000,00 € -

220RF-2018-12368286 CP

Phase II Study of systemic and intrarterial hepatic Peptide Receptors Radionuclide Therapy (PRRT) in liver-dominant gastroenteropancreatic neuroendocrine tumors 24,50



221RF-2018-12367408 CP

Anatomic substrate evaluation by Multi-Detector-Computed-Tomography cardiac imaging for electroanatomic mapping and radiofrequency ablation of ventricular tachycardia 24,50


222RF-2018-12366843 CP

Nutriepigenomics and lifestyle changes for primary prevention of breast and ovarian cancer in subjects with BRCA1 and BRCA2 germline mutations 24,50 Genes, Genomes and Genetics Oncologia Emilia-Romagna € 449.500,00 € -

29

BANDO 2018(fondo 2016-2017)


N. Code

Research

type Title

Voto finale


MOH IPOTESI


Finanziamento

223RF-2018-12365523 CP

Production of living three leaflet Aortic Valve substitutes by controlled recellularization process of xenogen-free decellularized pericardium 24,50

Surgical Sciences, Biomedical Imaging, and Bioengineering Cardiologia-Pneumologia MONZINO € 450.000,00 € -

224RF-2018-12365847 CP

Safety of cryopreserved ovarian tissue transplant: improving life quality in sarcoma and hematological cancer survivors 24,50


225RF-2018-12365651 CP

COmparison of Surgical vs TAVI interventions in patients with severe aortic stenOsis at intermediate risk: a randomized pilot trial. (COSTO Trial) 24,50

Cardiovascular and Respiratory Sciences Cardiologia-Pneumologia Emilia-Romagna € 450.000,00 € -

226RF-2018-12366994 CP

Vascular, metabolic and autonomic mechanisms contributing to myocardial ischemia and heart failure in hypertrophic cardiomyopathy 24,50


227RF-2018-12365686 CP

Microfluidics and comprehensive genomics of patient-derived organoids to treat esophageal cancer 25,00

Oncology 2 - Translational Clinical Oncologia SAN RAFFAELE MILANO € 450.000,00 € -

228RF-2018-12365999 CP

Peritoneal metastases from colorectal cancer: early treatment, biological risk factors, and mechanisms of progression. 25,00



229RF-2018-12367465 CP

Implementation of the National Plan of interventions against HIV/AIDS to control spreading of HIV, HBV and HCV infections in the community of inmates in Italy 25,00 AIDS and Related Research Malattie Infettive


230RF-2018-12368040 CP

Exploring the zoonotic potential of water buffaloes by investigation of the enteric and milk virome. 25,00 Veterinary Diagnostica IZSME € 450.000,00 € -

231RF-2018-12367297 CP

Utilization, Effectiveness and Safety of pharmaceutical treatments in Special Populations with Inflammatory Bowel Diseases: multiregional, population-based cohort study on pediatric, maternal and birth outcomes (SPESIBD) 25,00

Healthcare Delivery and Methodologies Gastroenterologia Lazio € 300.000,00 € -

30

BANDO 2018(fondo 2016-2017)


N. Code

Research

type Title

Voto finale


MOH IPOTESI


Finanziamento

232RF-2018-12367902 CP

Genetic Variation Of Dopamine D2 Receptor And Response To Antipsychotic Medications In Patients With Behavioural And Psychological Symptoms Of Dementia 25,00 Genes, Genomes and Genetics Geriatria I.N.R.C.A. € 310.000,00 € -

233RF-2018-12367555 CP

A NOVEL PERSONALIZED APPROACH FOR KNEE OSTEOARTHRITIS: PREDICTING TREATMENT RESPONSE VIA PHENOTYPING OF IMMUNE MECHANISMS (OA-PATH) 25,00

Musculoskeletal, Oral and Skin Sciences Ortopedia HUMANITAS € 450.000,00 € -

234RF-2018-12367633 CP

Combining cognitive remediation and neurostimulation for the treatment of executive impairment, craving and psychological well-being in alcohol use disorder: a randomized double-blind placebo-controlled study with neuro-cognitive markers and predictors of 25,50

Brain Disorders and Clinical Neuroscience Riabilitazione MAUGERI € 450.000,00 € -

235RF-2018-12367838 CP

Prognostic impact of early cardiological evaluation and identification of biomarkers of increased cardiovascular risk in patients hospitalized for acute exacerbation of chronic obstructive pulmonary disease (COPD): a prospective randomized study. 25,50


236RF-2018-12367429 CP

Biobanking in Rare thoracic tumors: genetical, epigenetic and therapeutical advances 25,50 Oncology 1 - Basic Translational Oncologia REGINA ELENA € 450.000,00 € -

237RF-2018-12367296 CP

Application of Radiogenomics in thyroid carcinoma 25,50

Oncology 2 - Translational Clinical Oncologia SDN € 300.000,00 € -

238RF-2018-12367783 CP

Salt sensitivity predicts renal and cardiovascular outcomes: an integrated risk score 25,50

Digestive, Kidney and Urological Systems Nefrologia e Urologia SAN RAFFAELE MILANO € 450.000,00 € -

239RF-2018-12367497 CP

Efficacy of epilepsy surgery in adults and children. Welfare consequences for people with drug resistant focal epilepsy. 25,50

Healthcare Delivery and Methodologies Neurologia


31

BANDO 2018(fondo 2016-2017)


N. Code

Research

type Title

Voto finale


MOH IPOTESI


Finanziamento

240RF-2018-12367672 CP

A MultiComponent Intervention to counteract sarcopenia and improve functional recovery in hip fracture older persons 25,50

Musculoskeletal, Oral and Skin Sciences Geriatria


241RF-2018-12367803 CP

Critical revision of the drug therapy, multidimentional evaluation of health status and predictive biomarkers in the context of the "Centenari a Trieste (CaT)" Study 26,00

Biology of Development and Aging Geriatria Friuli-Venezia Giulia € 420.100,00 € -

242RF-2018-12368240 CP

Unravelling the role of PI3K/MTOR pathway and alterations of cell cycle in the pathogenesis of thymic epithelial tumors (TETs):a single arm phase II trial with a dual PI3K/mTOR inhibitor plus a CDK4-6 inhibitor in advanced inoperable TETs 26,00

Oncology 2 - Translational Clinical Oncologia I.E.O. € 338.700,00 € -

243RF-2018-12366910 CP

Applying RNA FISH (RNA fluorescence in situ hybridization) technique to detect metastatic predictor MALAT1 in triple-negative breast cancer: a diagnostic tool for risk of relapse evaluation in lymph node negative patients 26,50


244RF-2018-12367810 CP

Phase IV Open label, assessor-blinded randomized, parallel group pragmatic clinical trial eValuating safEty, efficacy, immunogenicity, and cost-effectiveness of switching from oRiginator anti-TNF to biosimilar Compared with maintained treatment with Origi 26,50

Musculoskeletal, Oral and Skin Sciences Ematologia e Immunologia Emilia-Romagna € 449.500,00 € -

245RF-2018-12365143 CP

Drug repositioning: use of HIV protease inhibitor for the therapy of cervical cancer in HIV-infected or uninfected women 26,50



246RF-2018-12367621 CP

Epigenetic and neural correlates of placebo-related expectations in the treatment of acute postoperative pain 27,00

Biobehavioral and Behavioral Processes Ostetricia e Ginecologia FONDAZIONE GEMELLI € 297.300,00 € -

32

BANDO 2018(fondo 2016-2017)


N. Code

Research

type Title

Voto finale


MOH IPOTESI


Finanziamento

247RF-2018-12368089 CP

Correlations among changes in the gut microbiome, immune T-cell responses and potential clinical benefit of the addition of the antibiotic clarithromycin to conventional immunotherapy in patients with newly diagnosed follicular lymphoma

27,00Oncology 2 - Translational Clinical Ematologia e Immunologia SAN RAFFAELE MILANO € 449.800,00 € -

248RF-2018-12365870 CP

Phenotypic profile of circulating monocytes: possible implications for coronary plaque morphology and activity 27,00

Cardiovascular and Respiratory Sciences Cardiologia-Pneumologia MONZINO € 439.500,00 € -

249RF-2018-12367992 CP

WEREABLE DEFIBRILLATOR IN PREVENTION OF SUDDEN DEATH OF PATIENTS WITH BIOPSY-PROVEN MYOCARDITIS 27,00

Cardiovascular and Respiratory Sciences Cardiologia-Pneumologia FONDAZIONE GEMELLI € 448.428,00 € -

250RF-2018-12366272 CP

Enhancement of Natural Killer cell activity by first-line hormone therapy in ER/PgR positive low-grade ovarian cancer. A randomized phase II trial. 27,00

Oncology 2 - Translational Clinical Oncologia Liguria € 449.900,00 € -

251RF-2018-12367123 CP

Outpatient parenteral therapy for exacerbations of cystic fibrosis: a multilevel cost-benefit analysis 27,00

Healthcare Delivery and Methodologies Cardiologia-Pneumologia MAGGIORE € 439.160,00 € -

252RF-2018-12368280 CP

Enhancing the activity of hormone treatments for breast cancer by a fasting-mimicking diet 27,00


Ospedale Policlinico San Martino € 450.000,00 € -

253RF-2018-12365817 CP

Natural and anthropogenic environmental pollution by inorganic arsenic: a neglected risk factor for cardiovascular disease. Assessment of the impact on the public health in three Italian polluted regions. 27,00

Cardiovascular and Respiratory Sciences Cardiologia-Pneumologia Lombardia € 444.500,00 € -

254RF-2018-12367909 CP

DISSECTING THE COMPLEXITY OF ELDERLY PATIENTS WITH DIFFUSE LARGE B-CELL LYMPHOMA THROUGH A MULTIDIMENSIONAL APPROACH INTEGRATING CLINICAL, SOCIAL AND BIOMOLECULAR ASPECTS 27,00

Oncology 2 - Translational Clinical Ematologia e Immunologia


33

BANDO 2018(fondo 2016-2017)


N. Code

Research

type Title

Voto finale


MOH IPOTESI


Finanziamento

255RF-2018-12367628 CP

Impact of Immune-related prognostic index (IRPI) in the clinical management of patients with oral cancer 27,50

Oncology 2 - Translational Clinical Otorinolaringoiatria e Odontoiatria Lombardia € 450.000,00 € -

256RF-2018-12365791 CP

Endothelial shear stress as a predictor of cardiovascular diseases: evaluating its effectiveness,also regarding its modulation through therapies for chronic diseases, in a longitudinal study. 27,50 Vascular and Hematology Cardiologia-Pneumologia Calabria € 290.000,00 € -

257RF-2018-12366999 CP

Interaction and synergysm between physical exercise and a new drug (Sacubitril/Valsartan) in congestive heart failure: effects on functional capacity, quality of life and biomolecular markers (miRNAs and telomerase). 27,50

Cardiovascular and Respiratory Sciences Riabilitazione MAUGERI € 450.000,00 € -

258RF-2018-12367016 CP

Clinical evaluation of both epigenetic sensitive markers and cardiac imaging in patients with severe coronary heart disease 27,50

Cardiovascular and Respiratory Sciences Cardiologia-Pneumologia SDN € 397.500,00 € -

259RF-2018-12368203 CP

Vasopressin, a novel diagnostic and prognostic marker of Small Cell Lung Cancer (SCLC), hyponatremia and syndrome of inappropriate antidiuresi (SIAD). The VASCA Study

27,50Oncology 2 - Translational Clinical Oncologia Marche € 409.200,00 € -

260RF-2018-12366566 CP

Radiogenomic study to identify high-grade soft tissue sarcoma patients at risk of recurrence 28,00

Healthcare Delivery and Methodologies Oncologia REGINA ELENA € 448.577,00 € -

261RF-2018-12368191 CP

Evaluation of breath analysis in patients before colonoscopy as a mean to avoid unnecessary procedures 28,50

Oncology 2 - Translational Clinical Oncologia Lombardia € 422.700,00 € -

262RF-2018-12368389 CP

Dual-Energy CT scan for early individuation and characterisation of lung involvement in Systemic Sclerosis 28,50

Population Sciences and Epidemiology Ematologia e Immunologia MAGGIORE € 401.803,00 € -

34

BANDO 2018(fondo 2016-2017)


N. Code

Research

type Title

Voto finale


MOH IPOTESI


Finanziamento

263RF-2018-12367858 CP

Clinical evaluation of a new NGS HRD signature in predicting Parp inhibitors efficacy in advanced ovarian cancer 28,50



264RF-2018-12368160 CP

Relationship between frailty status and circulating pro-angiogenic progenitor cells in elderly patients with severe aortic stenosis undergoing transluminal aortic valve replacement 28,50


265RF-2018-12367174 CP

Assessment of graft pathology after heart transplantation using non-invasive imaging: a cardiovascular magnetic resonance T1 mapping study. 29,00


266RF-2018-12367003 CP

ORTHO-START: A prospective registry to evaluate the perioperative management of anticoagulation in patients approaching orthopedic surgery for a femur fracture 29,00 Vascular and Hematology Ematologia e Immunologia

CASA SOLLIEVO SOFFERENZA € 240.000,00 € -

267RF-2018-12365238 CP

Estradiol and its metabolites may be accurate biomarkers and targets in mesothelioma treatment ? 29,00


268RF-2018-12366588 CP

Novel predisposing genes for familial breast cancer: identification of cellular and molecular alterations (REBECCA) 29,50 Genes, Genomes and Genetics Oncologia Emilia-Romagna € 396.810,00 € -

269RF-2018-12368310 CP

An italian seminal project of an integrative human uterine microbiome database to collectinformation on a possible relationship between uterine microbiome modifications andpregnancies complications or endometrial cancer 29,50

Endocrinology, Metabolism, Nutrition and Reproductive Sciences Ostetricia e Ginecologia

CASA SOLLIEVO SOFFERENZA € 360.000,00 € -

270RF-2018-12365382 CP

Innovative approach to global management of cancer patients: The "Fluid CAS" model within the Piedmont Oncology Network 29,50


35

BANDO 2018(fondo 2016-2017)


N. Code

Research

type Title

Voto finale


MOH IPOTESI


Finanziamento

271RF-2018-12367368 CP

Pharmacogenetics and pharmacokinetics of ketamine in children presenting adverse events during procedural analgesia and sedation outside of the operating room. 29,50

Surgical Sciences, Biomedical Imaging, and Bioengineering Pediatria BURLO GAROFOLO € 449.000,00 € -

272RF-2018-12365380 CP

Whole liquid biopsy analysis in NSCLC patients through new platforms and new bioinformatics tools. 30,00


273RF-2018-12367930 CP

Impact of age- and drug-related epimicrobiome alterations on host epigenome : implications for multimorbidity in the elderly 30,00 Genes, Genomes and Genetics Geriatria I.N.R.C.A. € 448.778,00 € -

274RF-2018-12367454 CP

Human amniotic membrane as scaffold for tissue engineering: clinical application in pediatric urologic surgery. 30,00

Surgical Sciences, Biomedical Imaging, and Bioengineering Nefrologia e Urologia Sicilia € 437.500,00 € -

275RF-2018-12365628 CP

Real world evidence for improving diagnosis and treatment of Parkinson's disease: toward an integrated care. 30,00

Healthcare Delivery and Methodologies Neurologia Umbria € 320.850,00 € -

276RF-2018-12367175 CP

Splicing signatures as prognostic and therapeutic targets for pancreatic cancer 30,00


277RF-2018-12367581 CP

Seizure Treatment in Children Transported to Three National Third-Level Paediatric Hospitals: National Guideline Recommendation Adherence and Outcomes 30,50

Healthcare Delivery and Methodologies Neurologia Toscana € 300.505,00 € -

278RF-2018-12366698 CP

Lesson from long-term survivors among ovarian cancers: can it help to unravel factors of less aggressive disease? 31,00 Oncology 1 - Basic Translational Oncologia


279RF-2018-12365152 CP

Rational drug repositioning for an efficient and safe combined therapeutic approach to glioblastoma multiforme 31,50


280RF-2018-12367359 CP

Physiopathology of the end-stage cardiorenal syndrome and optimization of related ultrafiltration therapy 32,00


36

BANDO 2018(fondo 2016-2017)


N. Code

Research

type Title

Voto finale


MOH IPOTESI


Finanziamento

281RF-2018-12367843 CP

A REDUCED ANTICOAGULANT TREATMENT FOR ISOLATED DISTAL DEEP VEIN THROMBOSIS IN HOSPITALIZED PATIENTS: THE CALF-HO STUDY 32,50


282RF-2018-12365255 CP

Development and dissemination of Communication strategies for evidence based Informed Decision making in the field of drug Addiction in Italy (DeCIDA.It) 32,50

Healthcare Delivery and Methodologies Malattie Psichiatriche Lazio € 275.000,00 € -

283RF-2018-12366742 CP

Development and validation of an innovative approach to early and non-invasive detection of prostate cancer thorough an electronic nose. 32,50

Bioengineering Sciences and Technologies Oncologia HUMANITAS € 450.000,00 € -

284RF-2018-12368133 CP

RECORD: Rehabilitating Elderly with COntinous Recording Devices 33,00

Healthcare Delivery and Methodologies Cardiologia-Pneumologia MULTIMEDICA € 350.000,00 € -

285RF-2018-12367337 CP

Italian registry for Chiari I Malformation: collaborative study on epidemiology, natural history, surgical outcome, associated pathologies and genetic basis. 33,50

Bioengineering Sciences and Technologies Neurologia CARLO BESTA € 448.998,00 € -

286RF-2018-12367333 CP

Desensitization procedures for biologic agents (anti-HER2, anti-PD1/PDl1, Anti-CD20) in neoplastic patients exhibiting acute hypersensitivity reactions to the drugs and with no alternative options 34,00 Immunology Ematologia e Immunologia Toscana € 448.000,00 € -

287RF-2018-12365798 CP

Chronic Urticaria in children: comorbities, diagnosis and management 34,50 Immunology Pediatria Sicilia € 257.500,00 € -

288RF-2018-12367671 CP

Chronotherapy in Heart Failure: Conventional versus Temporized therapy in Heart Failure (CONVERT-HF) 35,00 Vascular and Hematology Cardiologia-Pneumologia Emilia-Romagna € 337.500,00 € -

37

BANDO 2018(fondo 2016-2017)


N. Code

Research

type Title

Voto finale


MOH IPOTESI


Finanziamento

289RF-2018-12366058 CP

A new methodological approach to study the interaction of intestinal microbiota and its modulation with the clinical features of hepatic encephalopathy

35,00Infectious Diseases and Microbiology Gastroenterologia DE BELLIS € 440.000,00 € -

290RF-2018-12368277 CP

What people know and should know about vectors transmitting diseases? Planning and implementation of an information strategy focused on the control of arthropods vectors and the prevention of related diseases. 35,00

Healthcare Delivery and Methodologies Malattie Infettive IZSSI € 320.000,00 € -

291RF-2018-12366916 CP

Targeting active ADAM10 isoform in rectal cancer as marker for neoadjuvant therapy resistance 35,00

Oncology 2 - Translational Clinical Oncologia SAN RAFFAELE MILANO € 450.000,00 € -

292RF-2018-12368059 CP

Evaluation of effectiveness and safety for medical cannabis oil capsules in eligible patients 35,50


293RF-2018-12367083 CP

Identification of immune signatures predictive of clinical response to check-point inhibitors in metastatic clear cell renal cancer patients.

35,50Oncology 2 - Translational Clinical Oncologia Emilia-Romagna € 330.000,00 € -

294RF-2018-12365809 CP

Definition of sanification protocols based on metagenomics. 37,00

Infectious Diseases and Microbiology Malattie Infettive Sicilia € 450.000,00 € -

295RF-2018-12368318 CP

Creation of a digital environment integrating the WHO international classification systems for personalized neurorehabilitation 37,50

Healthcare Delivery and Methodologies Riabilitazione MAUGERI € 378.800,00 € -

296RF-2018-12366719 CP

A prospective, observational, multicentric study evaluating effectiveness, safety and budget impact model of etanercept biosimilar SB4 in a cohort of psoriasis arthritis patients. Comparison with two historical cohorts of psoriasis arthritis subjects tr 39,00

Musculoskeletal, Oral and Skin Sciences Dermatologia SAN GALLICANO € 250.000,00 € -

38

BANDO 2018(fondo 2016-2017)


N. Code

Research

type Title

Voto finale


MOH IPOTESI


Finanziamento

297RF-2018-12367819 CP

Design and protocol monitoring spinal disorder using data yielded by the SpineReg registry mobile application: an effective smart tool for spinal surgeons 40,00

Bioengineering Sciences and Technologies Ortopedia GALEAZZI € 281.000,00 € -

298RF-2018-12367632 CP

A basal and longitudinal multimarker based CV risk stratification and prevention strategy in subjects living in a contaminated site. 41,50

Cardiovascular and Respiratory Sciences Cardiologia-Pneumologia Toscana € 400.000,00 € -

39

BANDO 2018(fondo 2016-2017)

Classifica e Finanziamento Progetti RF Change PromotingPROGETTI NON INVIATI IN VALUTAZIONE A SEGUITO DEL TRIAGE

N. CODICE TIPO TITOLO IRG MDC DESTINATARIO VOTO_CV

299 RF-2018-12365118

CP Towards prevention of type 2 diabetes (T2D) development in women with gestational diabetes mellitus (GDM): investigation on predictive and treatment-response biomarkers following dietary polyphenols in GDM tissues by correlating adipose tissue and circulating factors

Endocrinology, Metabolism, Nutrition and Reproductive Sciences

Endocrinologia Istituto Superiore di Sanita' 8,00

300 RF-2018-12365215

CP Prognostic and predictive value of androgen receptor in patients with ductal carcinoma in situ of the breast

Oncology 2 - Translational Clinical Oncologia I.E.O. 8,00

301 RF-2018-12365498

CP Ocular immunohistochemistry of vernal keratoconjunctivitis, clinical safety and tolerability of novel therapies in children: Evaluation of the lacrimal and serum biomarkers, before and after treatment with immunomodulatory and antinflammatory drugs.

Brain Disorders and Clinical Neuroscience

Oculistica Lazio 8,00

302 RF-2018-12365524

CP Efficacy of fMRI and tractography in improving seizure and functional outcome after epilepsy surgery in children


Neurologia Toscana 8,00

303 RF-2018-12365541

CP Effect of atorvastatin administration in hyperacute ischemic stroke: functional outcome, modulation of collateral flow and related biomarkers.


Neurologia Lazio 8,00

304 RF-2018-12365726

CP The impact of mini-invasive surgery and Enhanced Recovery (ERAS) program plus immunonutrition to accelerate postoperative functional recovery: clinical outcomes and development of an experimental model of immune and stress mediators in patients undergoing radical resection for colorectal cancer

Surgical Sciences, Biomedical Imaging, and Bioengineering

Oncologia FONDAZIONE GEMELLI 8,00

305 RF-2018-12365919

CP Personalizing radiotherapy treatment for prostate and cervical cancers: development of a genome-&-radiomic based tumor control probability model

Oncology 2 - Translational Clinical Oncologia ISTITUTO TUMORI MILANO 8,00

306 RF-2018-12366118

CP Varenicline versus cytisine: a pharmacogenomics approach Genes, Genomes and Genetics Cardiologia-Pneumologia ISTITUTO TUMORI MILANO 8,00

307 RF-2018-12366161

CP Reduced recovery time for full visual recovery and reduced risk in patients with diabetic retinopathy following cataract surgery: reduced corneal and retinal trauma due to less energy required for cataract emulsification using nanolaser instead of phaco-energy in both manual and femtolaser assisted cataract surgery


Oculistica BIETTI 8,00

308 RF-2018-12366200

CP Development and validation of peri-operative management of patients with pituitary adenoma in the era of the Pituitary Tumor Centers of Excellence (PTCOE)


Endocrinologia Veneto 8,00

309 RF-2018-12366394

CP Circulating tumor-derived microvesicles and endothelial cells as predictive factors of response

to anti-cancer treatment

Oncology 2 - Translational Clinical Oncologia Abruzzo 8,00

BANDO 2018(fondo 2016-2017)



310 RF-2018-12366814

CP ASSESSING THE EFFECTIVENESS, COST-EFFECTIVENESS, ACCEPTABILITY AND IMPACT ON PRACTICE OF A PATIENT-REPORTED OUTCOME MEASURE REGISTRY PROGRAM FOR TOTAL HIP AND TOTAL KNEE ARTHROPLASTY

Healthcare Delivery and Methodologies Ortopedia GALEAZZI 8,00

311 RF-2018-12366889

CP From in-hospital to early discharge phase: Supporting Informal Caregivers of individuals with

severe Acquired Brain Injury (sABI) and effects on the healthcare process.

Healthcare Delivery and Methodologies Riabilitazione Umbria 8,00

312 RF-2018-12366924

CP Can Physical Exercise Modulate Brain Plasticity And Connectivity? A Multimodal Neuroimaging Study In Bipolar

Continuum Across The Lifespan


Malattie Psichiatriche Veneto 8,00

313 RF-2018-12367125

CP OVERRIDE CHEMORESISTANCE IN EVI-1 ACUTE MYELOID LEUKEMIA

Vascular and Hematology Ematologia e Immunologia Emilia-Romagna 8,00

314 RF-2018-12367179

CP Obstacles to HCV elimination among persons with HIV in Italy. A modeling approach to estimate size and characteristics of the undiagnosed HCV population and next-generation sequencing analysis of HCV isolates to characterize transmission networks in key populations

Population Sciences and Epidemiology Malattie Infettive SPALLANZANI 8,00

315 RF-2018-12367260

CP Plasma metabolic biosignatures to predict safety of first line antiretroviral therapies in HIV positive subjects: focus on glucose, lipids and bone metabolism

AIDS and Related Research Malattie Infettive SPALLANZANI 8,00

316 RF-2018-12367390

CP Exploring the cross-talk between growth factors and lipid-derived mediators as an innovative approach to promote wound healing.

Musculoskeletal, Oral and Skin Sciences Dermatologia SAN GALLICANO 8,00

317 RF-2018-12367399

CP Lipidome, aminoacidome, and microflora interplay at the skin surface: Perspectives for the exploitation of inherent factors in the precision management of atopic dermatitis.


318 RF-2018-12367403

CP Targeting the adenosinergic system in patients with Restless Legs Syndrome: insights from Transcranial Magnetic Stimulation


Neurologia Associazione Oasi Maria SS 8,00

319 RF-2018-12367505

CP Characterization of treatment effects and progression disease by multi parametric C11-MET PET/MR-PWI in

glioblastoma patients

Oncology 2 - Translational Clinical Diagnostica SAN RAFFAELE MILANO 8,00

320 RF-2018-12367579

CP Bone and heart are connected by a cross-talk that links bone structural and heart functional failures in stress and aging: investigating the role of FGF23/21 and circulating miRNA. A proof of concept.

Biology of Development and Aging Ortopedia SAN RAFFAELE MILANO 8,00

321 RF-2018-12367650

CP Parameters Expressing Neurocognitive Evil Load Of Paroxysmal Epileptiform activity during Sleep in Focal Idiopathic Epilepsies at Risk of Conversion in Encephalopathy (PENELOPE'S FIERCE)


Neurologia Veneto 8,00

BANDO 2018(fondo 2016-2017)



322 RF-2018-12367673

CP CARCINOGENIC RISK OF NARROW BAND ULTRAVIOLET B (NB UVB)

Risk, Prevention and Health Behavior Dermatologia SAN GALLICANO 8,00

323 RF-2018-12367686

CP Relapsed/refractory immune-mediated cytopenia in primary immunodeficiencies: patients¿ stratification and personalized therapy based on identification of specific altered pathways/markers

Immunology Ematologia e Immunologia OSPEDALE BAMBINO GESU' 8,00

324 RF-2018-12367717

CP Gompertz's survivorship law is a practical method to understand end-of-life time in admitted patients

Population Sciences and Epidemiology Geriatria Emilia-Romagna 8,00

325 RF-2018-12367762

CP Personalised Multi-Factorial Clinical Decision Making in Complex Surgical Interventions: Right Ventricular Failure Risk Prediction in Patients Referred for Left Ventricular Assist Device Implantation (RiVeR)

Cardiovascular and Respiratory Sciences

Cardiologia-Pneumologia ISMETT 8,00

326 RF-2018-12367804

CP Endoscopic ultrasound-guided cryothermal ablation for the treatment of stage III (locally advanced and borderline resectable) pancreatic ductal adenocarcinoma: a

randomized controlled phase II/a efficacy clinical trial

Oncology 2 - Translational Clinical Oncologia SAN RAFFAELE MILANO 8,00

327 RF-2018-12367821

CP Predictive biomarkers of response to the novel PDGFRalpha-targeting antibody Olaratumab in Soft Tissue Sarcoma

Oncology 2 - Translational Clinical Oncologia I. O. V. 8,00

328 RF-2018-12367837

CP THD vs Emborroid: prospective randomized trial for the dearterialization of hemorrhoids.


Gastroenterologia Umbria 8,00

329 RF-2018-12367845

CP Fibrin-based sensorized dressing for delivery of cord blood platelet lysate in wound healing treatment.

Bioengineering Sciences and Technologies

Dermatologia Toscana 8,00

330 RF-2018-12367857

CP GENETIC AND BIOUMORAL FACTORS PREDISPOSING TO DEVELOP MENIERE'S DISEASE AND VESTIBULAR MIGRAINE: AN INTEGRATIVE APPROACH TO EPISODIC VERTIGO

Genes, Genomes and Genetics Otorinolaringoiatria e Odontoiatria

SAN RAFFAELE MILANO 8,00

331 RF-2018-12367931

CP CEntral Nervous system TOXicity after Irradiation for skull base/head-neck Cancers: the CENTOXIC study

Oncology 2 - Translational Clinical Neurologia MONDINO 8,00

332 RF-2018-12368049

CP A new approach toward a rationalization of combination therapies with molecularly targeted agents, in colorectal cancer. An innovative rationalization of combined treatments, implementing a mathematical dynamic-model based on quantitative computational analyses, NGS

characterization in primary tumors and in liquid biopsies. Toward a new informatic decision-support for the clinician.

Oncology 2 - Translational Clinical Oncologia Liguria 8,00

BANDO 2018(fondo 2016-2017)



333 RF-2018-12368134

CP Inside out the brain. Optimizing Electrical Source Imaging (ESI) techniques and assessing the epileptogenic zone through simultaneous recordings of intracerebral (Stereo-EEG) and surface (High-density EEG) electrophysiological signals in drug-resistant epileptic patients.


Neurologia Lombardia 8,00

334 RF-2018-12368186

CP MONITORING AND PHARMACOLOGICAL PREVENTION OF CARDIOTOXICITY CAUSED BY ANTHRACYCLINE +/- TRASTUZUMAB IN BREAST CANCER: THE EFFECTS OF TREATMENT WITH ACE INHIBITORS AND BETA BLOCKERS (SAFE TRIAL 2014)

Oncology 2 - Translational Clinical Cardiologia-Pneumologia Toscana 8,00

335 RF-2018-12368212

CP Myoclonus in progressive myoclonus epilepsies and in atypical parkinsonian syndromes; distinctive features and quantification using multiple neurophysiological techniques. Transcranial Direct Current Stimulation to treat the motor impairment in selected patient subgroups.


Neurologia CARLO BESTA 8,00

336 RF-2018-12368239

CP Tau and ApoE interaction: different mechanisms of neurodegeration and novel therapeutic perspectives.


Neurologia SANTA LUCIA 8,00

337 RF-2018-12368247

CP An innovative surgical guidance approach in brain tumour surgery: the role of rapid evaporative ionization mass spectrometry (REIMS).

Emerging Technologies and Training in Neurosciences

Oncologia Sicilia 8,00

338 RF-2018-12368332

CP Biomarkers and precision therapy for interferonopathies: an ex vivo study in inducible pluripotent stem cells from patient with Aicardi-Goutières and Aicardi-Goutières-like syndrome

Immunology Pediatria Lombardia 8,00

339 RF-2018-12365663

CP WHOLE-BODY MAGNETIC RESONANCE IMAGING FOR DETECTION OF BONE DISEASE IN CHILDREN WITH LANGERHANS CELL HISTIOCYTOSIS. A PROSPECTIVE COMPARISON WITH X-RAY SKELETAL SURVEY


Diagnostica GASLINI 9,00

340 RF-2018-12365712

CP A phase II study on adjuvant Vaccination with dendritic cells loaded with autologous tumor homogenate in resected stage IV rare cancers: Head&Neck (H&N), neuroendocrine Tumors (NET) and soft tissue sarcoma (STS).

Oncology 2 - Translational Clinical Oncologia Istituto Scientifico Romagnolo 9,00

341 RF-2018-12366122

CP Simple prehabilitative strategies to improve the postoperative outcomes of elderly patients undergoing major elective vascular surgery.


Riabilitazione Emilia-Romagna 9,00

342 RF-2018-12366181

CP Brain stimulation and Vegetative State: role of neurophysiology in determining the correct use for transcranial electrical stimulation


Riabilitazione Toscana 9,00

343 RF-2018-12366326

CP Integrated Care Pathway for Diabetic Retinopathy : from screening to diabetic macular edema therapy

Healthcare Delivery and Methodologies Endocrinologia Piemonte 9,00

BANDO 2018(fondo 2016-2017)



344 RF-2018-12366360

CP DEFINITION OF A PROGNOSTIC PROTEOGLYCAN-CODE AS A NOVEL IMMUNE CHECKPOINT FOR MESOTHELIOMA PATIENTS UNDERGOING COMBINED IMMUNOTHERAPY WITH DENDRITIC CELL VACCINATION AND PD-1 CHECKPOINT BLOCKADE

Oncology 2 - Translational Clinical Oncologia Istituto Scientifico Romagnolo 9,00

345 RF-2018-12366728

CP Development of an easy to use method for the detection of HAV, NOV, RVA and HAdV in bivalve molluscs from natural breeding areas in Southern Italy.

Veterinary Diagnostica IZSME 9,00

346 RF-2018-12366845

CP NEXT GENERATION NEWBORN SCREENING: NGS ON DRIED BLOOD SPOTS

Genes, Genomes and Genetics Diagnostica Emilia-Romagna 9,00

347 RF-2018-12366856

CP MainstreamIng WEB-based Support services for Caregivers of frail Older PEople (MIWEBSCOPE)

Healthcare Delivery and Methodologies Geriatria I.N.R.C.A. 9,00

348 RF-2018-12366938

CP A combined approach in the second-line treatment of peritoneal carcinomatosis from gastric cancer: systemic and intraperitoneal pressurized aerosol chemotherapy (PIPAC) vs systemic chemotherapy alone. A randomized phase II trial

Oncology 2 - Translational Clinical Oncologia FONDAZIONE GEMELLI 9,00

349 RF-2018-12367004

CP Effect of immunosuppressive drugs on the gut microbiota of patients affected by axial spondylarthritis and correlation with their clinical outcome: an Exploratory Study

Infectious Diseases and Microbiology Malattie Infettive SPALLANZANI 9,00

350 RF-2018-12367049

CP Artificial intelligence techniques (machine learning and texture analysis) applied to 18F-Fluorodeoxyglucose PET/CT images to improve diagnosis and staging of lung cancer

Oncology 2 - Translational Clinical Diagnostica Umbria 9,00

351 RF-2018-12367115

CP EXPLOITING THE IMPACT OF PULMONARY INVOLVEMENT IN PAEDIATRIC RHEUMATIC DISEASES: AN INTEGRATIVE APPROACH FOCUSED ON BIOMARKER DISCOVERY AND CLINICAL MANAGEMENT INTERVENTION

Immunology Pediatria Marche 9,00

352 RF-2018-12367122

CP NEridronate and VItamin D treatment for the Osteochondrosis of the Spine (NEVIDOS)

Musculoskeletal, Oral and Skin Sciences Ortopedia GALEAZZI 9,00

353 RF-2018-12367192

CP Skin and internal diseases in immigrant population Population Sciences and Epidemiology Dermatologia SAN GALLICANO 9,00

354 RF-2018-12367372

CP Cancer-associated fibroblasts as target for skin cancer carcinoma


355 RF-2018-12367417

CP Improvement of Quality of Life and Continence Status in Patients after reconstructive surgery for bladder and prostate cancer: from computational biomechanics and narrative approaches to clinical practice


Nefrologia e Urologia Veneto 9,00

356 RF-2018-12367436

CP Restrictive and Enabling Techniques to Improve Quality of Antibiotic Prescriptions in hospitalized children: The RENTIQAP study

Healthcare Delivery and Methodologies Pediatria OSPEDALE BAMBINO GESU' 9,00

BANDO 2018(fondo 2016-2017)



357 RF-2018-12367467

CP The effect of melatonin supplementation and mindfulness-based stress reduction in subjective cognitive decline: a pilot randomized controlled trial


Geriatria FATEBENEFRATELLI 9,00

358 RF-2018-12367522

CP Observational no-profit protocol to monitor the prescriptions and the cost-effectiveness of PCSK9 inhibitors in Tuscany Region ¿ CERTI

Healthcare Delivery and Methodologies Cardiologia-Pneumologia Toscana 9,00

359 RF-2018-12367587

CP A randomised clinical trial on multidimensional rehabilitation program in lung cancer patients undergoing adjuvant therapy: impact on cancer-related fatigue, exercise capacity, mood disturbance, quality of life and activities of daily living.

Oncology 2 - Translational Clinical Oncologia AUSL RE Ist. Tecnologie Avanzate

9,00

360 RF-2018-12367622

CP Bioresorbable composite fixation systems for craniomaxillofacial surgery: definition of optimized use

guidelines and design of improved devices


Otorinolaringoiatria e Odontoiatria

FONDAZIONE GEMELLI 9,00

361 RF-2018-12367644

CP Immunogenic cell death as a novel mechanism of Mitomycin C activity in Bladder Cancer

Oncology 2 - Translational Clinical Oncologia HUMANITAS 9,00

362 RF-2018-12367674

CP A Functional-Based Approach to Imaging Invasive Fungal Disease in Hematology Patients

Infectious Diseases and Microbiology Ematologia e Immunologia Emilia-Romagna 9,00

363 RF-2018-12367740

CP Validation of the clinical impact of circulating biomarkers in the diagnosis, prognosis and follow up of differentiated thyroid cancer

Oncology 2 - Translational Clinical Endocrinologia Toscana 9,00

364 RF-2018-12367861

CP Patients with Brain tumor-related Epilepsy: Impact of an integrate mHealth platform and its mobile applications on clinical outcome, quality of care and burden on national healthcare system costs.

Healthcare Delivery and Methodologies Neurologia REGINA ELENA 9,00

365 RF-2018-12367914

CP Molecolar and clinical study of regenerative therapy efficacy in female Lichen Sclerosus using Non-invasive Microscopic Diagnostic Methods and Videotermography.


366 RF-2018-12368099

CP Achievement of a regional network for the management of disorders of sex development (DSD): proposal for a common diagnostic approach, clinical management and decision on

sex of rearing


Pediatria Emilia-Romagna 9,00

367 RF-2018-12368123

CP A comprehensive pre-Transcatheter Aortic Valve Replacement (TAVR) clinical pathway, including frailty, in elderly patients affected by degenerative aortic valve disease: a multidisciplinary Heart Team for an appropriate risk stratification, prognosis and personalized care.

Healthcare Delivery and Methodologies Cardiologia-Pneumologia Toscana 9,00

368 RF-2018-12368177

CP Early detection and management of cardiac involvement in systemic sclerosis

Musculoskeletal, Oral and Skin Sciences Diagnostica HUMANITAS 9,00

369 RF-2018-12368219

CP Faecal and oral microbiota for non invasive early detection of gastrointestinal cancer and precancerous conditions.

Oncology 2 - Translational Clinical Oncologia I. O. V. 9,00

BANDO 2018(fondo 2016-2017)



370 RF-2018-12368334

CP Impact of a clinically oriented diagnostic protocol (CODP) on diagnosis, cure and survival in patients with central and peripheral nervous system complications after allogeneic hematopoietic stem cell transplantation: a multicenter, interdisciplinary, prospective study.

Infectious Diseases and Microbiology Trapiantologia SAN MATTEO 9,00

371 RF-2018-12368349

CP Prognostic relevance of Inflammation and Amyloid burden in Vascular CognitivE impairment (PIAVE study)


Neurologia Liguria 9,00

372 RF-2018-12368378

CP Omics technologies in risk assessment and management during transition period to improve

animal welfare in intensive farms of water buffalo and dairy cow

Veterinary Ematologia e Immunologia IZSME 9,00

373 RF-2018-12368380

CP Effect of pre-surgery action observation therapy on speeding up functional recovery and decrease fear of movement after total hip arthroplasty.

Musculoskeletal, Oral and Skin Sciences Riabilitazione HUMANITAS 9,00

374 RF-2018-12365279

CP Use of viscoelastic tests in the treatment of trauma-induced coagulopathy: a pragmatic randomized clinical trial


Diagnostica Lombardia 10,00

375 RF-2018-12365667

CP Impact of BEnzylpenicillin prophylaxys on intestinal MIcrobiota and quality of life in children with RHEumatic Fever (BEMIRHEF)

Healthcare Delivery and Methodologies Pediatria MAGGIORE 10,00

376 RF-2018-12366136

CP Alternative splicing modulation of Ca2+ handling genes and intracellular Ca2+ signals: a new therapeutic target in myotonic dystrophy type 1 (DM1). A molecular and pharmacological translational study.

Genes, Genomes and Genetics Neurologia DON GNOCCHI 10,00

377 RF-2018-12366271

CP Improving the efficiency of breast radiotherapy treatment: full automation of contouring and planning.

Oncology 2 - Translational Clinical Oncologia Toscana 10,00

378 RF-2018-12366315

CP Positive Drinking Imitation Therapy: a new rehabilitative intervention protocol for Alcohol Use Disorder.


Neurologia Emilia-Romagna 10,00

379 RF-2018-12366521

CP High-throughput mutation screening of pure T-cell subpopulations as a guide to personalized medicine in celiac patients with a refractory disease

Digestive, Kidney and Urological Systems

Gastroenterologia MAGGIORE 10,00

380 RF-2018-12366523

CP New strategies for improving ß-blocker dosing regimen and outcomes in heart failure patients with systolic dysfunction


Cardiologia-Pneumologia Istituto Superiore di Sanita' 10,00

381 RF-2018-12366792

CP Different architetures of robotic devices for upper limb rehabilitation: a multiple arms randomized clinical trial

Bioengineering Sciences and Technologies

Riabilitazione Toscana 10,00

382 RF-2018-12367085

CP Ranolazine for prevention of Trastuzumab Induced Cardiotoxicity in breast cancer patients and preclinical evaluation of new highly bioavailable nanomedicines loaded with nutraceuticals as new cardioprotective tools in cardio-oncology


Cardiologia-Pneumologia PASCALE 10,00

383 RF-2018-12367094

CP The implementation of PRESTO algorithms into clinical practice: a strategy for improving rehabilitation efficiency and clinical outcomes after stroke. A single-site randomized control trial.

Biobehavioral and Behavioral Processes Riabilitazione Emilia-Romagna 10,00

BANDO 2018(fondo 2016-2017)



384 RF-2018-12367245

CP Genetic variability of LTR in relation to HIV compartmentalization and predisposition to therapy failure

AIDS and Related Research Malattie Infettive SPALLANZANI 10,00

385 RF-2018-12367305

CP Combining restorative factors secreted from mesenchymal stem cells for augmenting therapeutic effect in spinal cord injury


Neurologia MARIO NEGRI 10,00

386 RF-2018-12367434

CP The role of Frailty indicators in predicting structural, vascular, metabolic and functional alterations of the brain in cognitive decline and dementias.


Neurologia Veneto 10,00

387 RF-2018-12367464

CP Genetic background and brain connectivity changes in the evaluation of the effectiveness of Movement Cognition and Narration of the emotions Treatment versus usual care in the rehabilitation of children with Borderline Intellectual Functioning


Riabilitazione DON GNOCCHI 10,00

388 RF-2018-12367611

CP INTESTINAL MICROBIOTA AS PROTECTING/PREDISPOSING FACTOR FOR INFANT BOTULISM

Infectious Diseases and Microbiology Pediatria MAUGERI 10,00

389 RF-2018-12367926

CP A comparison between the diagnostic accuracy of ultrasound thoracic imaging and that of the other imaging techniques which are commonly used when assessing patients with heart failure, acute respiratory failure, pulmonary fibrosis and chronic obstructive pulmonary diseases, with the subsequent development of a clinical protocol for an effective ultrasound thoracic diagnosis.


Cardiologia-Pneumologia Toscana 10,00

390 RF-2018-12367977

CP Cutting edge Quality Assurance program with synergistic use of two in vivo monitoring devices during patient irradiation with intensity modulated external beams

Oncology 2 - Translational Clinical Oncologia Toscana 10,00

391 RF-2018-12367996

CP Frailty as a prognostic determinant of acute coronary syndrome in patients aged 75 or more: a comparison between different tools of frailty assessments

Biology of Development and Aging Cardiologia-Pneumologia I.N.R.C.A. 10,00

392 RF-2018-12368029

CP CHEMOBRAIN IN CANCER PATIENTS: FEATURES, IMPACT ON QUALITY OF LIFE, AND VALIDATION OF A SPECIFIC COGNITIVE TRAINING PROGRAM

Risk, Prevention and Health Behavior Oncologia C.R.O. AVIANO 10,00

393 RF-2018-12368251

CP Big data to assess environmental influences on accident and emergency presentations in fragile populations

Population Sciences and Epidemiology Oncologia ISTITUTO TUMORI MILANO 10,00

394 RF-2018-12368285

CP Evaluation of different formulations of supplementary iron therapy in treating pre-operative anaemia in patients undergoing major abdominal, gynaecological and orthopaedic surgical procedures.

Vascular and Hematology Ematologia e Immunologia SAN RAFFAELE MILANO 10,00

395 RF-2018-12368320

CP Incidence in pregnancy and rate of vertical transmission of non-primary human cytomegalovirus infection in Bologna metropolitan area

Healthcare Delivery and Methodologies Ostetricia e Ginecologia Emilia-Romagna 10,00

396 RF-2018-12368358

CP Bioabsorbable bioengineered vascular scaffold for in vivo creation of vascular grafts


Trapiantologia Sicilia 10,00

BANDO 2018(fondo 2016-2017)



397 RF-2018-12368408

CP PROGRaM - Fetal programing following in-utero growth restriction: impact on cardiac remodeling and functional parameters, epigenetic modulation and biomarkers


Ostetricia e Ginecologia BURLO GAROFOLO 10,00

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