beep baltic esbl epidemiology project paul naaber oct 2012, visby
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BEEP
Baltic ESBL Epidemiology Project
Paul NaaberOct 2012, Visby
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Diagnostics and education - impact to diagnostic quality* Improvement of screening and confirmation of ESBLs in
Baltic region* Educational activities
Epidemiology, surveillance - impact to public health* Evaluation of ESBLs epidemiology in E. coli and K.
pneumoniae (prevalence, types)
Research* Publications, Master/PhD degrees* Creation of culture collection of resistant E. coli and K.
pneumoniae strains for future studies* Scientific cooperation
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Participants (data and strain collection) = 21 LabsCollaborating institution
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• Feb 2011 - 1st BARN WS: presentation of project proposal
• March to Sept 2011: Estonian Pilot study (4 labs)
• Nov 2011: 2nd BARN WS: participants meeting, final protocol
• Jan - May 2012: study period
• Introduction of ESBL screening/confirmation methods
• Collection of strains and data in local labs
• Meetings in St. Petersburg and Vilnius
• June-Sept 2012:
• Collection of strains and data to study center
• ID- MALDI-TOF
• Extraction of DNA
• Master students training in Stockholm
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*Estonian pilot study completed (217 strains)*Poster presentation (World Congress of Microbes-2012
Guangzhou, China)
*All 21 BEEP institutions have sent data and strains*Totally 947 ESBL strains: 395 E. coli, 552 K. pneumoniae
*Data checking is ongoing
*DNA extraction and ID confirmation (MALDI-TOF) almost completed
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Esherichia coli Klebsiella pneumoniae
ESBL Out ESBL In ESBL Out ESBL In Carba In
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• Lab work• Molecular charactersation of ESBLs
• Seminars, meetings• Estonian meeting Nov 2012• Baltic meeting May? 2013
• Presentations, publications• Abstract to ECCMID
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Thanks to BARN, SMI and all participants
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