bioinformatics project

6
Bioinformatics Bioinformatics Project Project Lisa Leone Lisa Leone

Upload: adam-england

Post on 31-Dec-2015

15 views

Category:

Documents


0 download

DESCRIPTION

Bioinformatics Project. Lisa Leone. Gene Identification. Diapause vs. Non-diapause. Diapause vs. Non-diapause. 9699. Nedd2-like caspase. Threonyl-tRNA Synthetase. Biological process threonyl-tRNA aminoacylation Amino acid sequence Gene function serine specific Clustal W Alignment. - PowerPoint PPT Presentation

TRANSCRIPT

Page 1: Bioinformatics Project

Bioinformatics ProjectBioinformatics Project

Lisa LeoneLisa Leone

Page 2: Bioinformatics Project

Gene IdentificationGene Identification

CG #CG # Gene NameGene Name14221422 Vesicle docking proteinVesicle docking protein

32083208 RhoGAP5ARhoGAP5A

96999699 no nameno name

No CG: No CG: LP09975LP09975 Nedd2-like caspaseNedd2-like caspase

No CG: No CG: SD01519SD01519 Alanyl-tRNA synthetaseAlanyl-tRNA synthetase

No CG: SD02419No CG: SD02419 no nameno name

No CG: GH16320No CG: GH16320 no nameno name

53535353 Threonyl-tRNA synthetaseThreonyl-tRNA synthetase

42394239 no nameno name

1331613316 no nameno name

1792217922 no nameno name

Page 3: Bioinformatics Project

Diapause vs. Non-diapauseDiapause vs. Non-diapause CG#CG# Gene NameGene Name Diapause/Non-diapauseDiapause/Non-diapause

14221422 Vesicle docking proteinVesicle docking protein DiapauseDiapause

32083208 RhoGAP5ARhoGAP5A DiapauseDiapause

No CG: No CG: SD01519SD01519 Alanyl-tRNA synthetaseAlanyl-tRNA synthetase DiapauseDiapause

No CG: SD02419No CG: SD02419 no nameno name DiapauseDiapause

No CG: GH16320No CG: GH16320 no nameno name DiapauseDiapause

53535353 Threonyl-tRNA synthetaseThreonyl-tRNA synthetase DiapauseDiapause

42394239 no nameno name DiapauseDiapause

1331613316 no nameno name DiapauseDiapause

1792217922 no nameno name DiapauseDiapause

No CG: LP09975No CG: LP09975 Nedd2-like caspaseNedd2-like caspase Non-diapauseNon-diapause

96999699 no nameno name Non-diapauseNon-diapause

Page 4: Bioinformatics Project

Diapause vs. Non-diapauseDiapause vs. Non-diapause

p115

RhoGAP5A

GH16320

Threonyl-tRNA synthetase

4239

13316

17922

Alanyl-tRNA synthetase

SD02419

-0.2-0.1

00.10.20.30.40.50.60.70.80.9

11.11.21.31.41.5

Diapause

Non-diapause

9699 Nedd2-like caspase

Page 5: Bioinformatics Project

Threonyl-tRNA Threonyl-tRNA SynthetaseSynthetase

Biological processBiological processthreonyl-tRNA aminoacylationthreonyl-tRNA aminoacylation

Amino acid sequenceAmino acid sequence Gene functionGene function

serine specificserine specific

ClustalClustal W W AlignmentAlignment

Page 6: Bioinformatics Project

ReferencesReferences

Beebe, Kirk. Elucidation of tRNA-dependent editing by a class II Beebe, Kirk. Elucidation of tRNA-dependent editing by a class II tRNA synthetase and significance for cell viability. The European tRNA synthetase and significance for cell viability. The European Molecular Biology Organization Journal, 2003. 22 (3), 668-675.Molecular Biology Organization Journal, 2003. 22 (3), 668-675.

Caillet, Joel. The modular structure of Caillet, Joel. The modular structure of E.coliE.coli threonyl-tRNA threonyl-tRNA synthetase as both an enzyme and a regulator of gene synthetase as both an enzyme and a regulator of gene expression. Molecular Microbiology, 2003. 47 (4), 961-974.expression. Molecular Microbiology, 2003. 47 (4), 961-974.

Sacerdot, Christine. The Sacerdot, Christine. The E.coliE.coli threonyl-tRNA synthetase gene threonyl-tRNA synthetase gene contains a split ribosomal binding site interrupted by a hairpin contains a split ribosomal binding site interrupted by a hairpin structure that is essential for autoregulation. Molecular structure that is essential for autoregulation. Molecular Microbiology, 1998. 29 (4), 1077-1090.Microbiology, 1998. 29 (4), 1077-1090.