bios 220 - l1 cells and genes

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    BioS 220 Mendelian andMolecular Genetics

    Lecture 1. Cells and Genes

    Chapter 1

    Overview of genetics and the course

    Syllabus

    Some housekeeping details

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    Why Genetics?

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    Fig. 1 Swarna (left) and Swarna-Sub1 (right) in a farmer's field

    after 10 days of complete submergence with turb id water in

    Uttar Pradesh, India. The photo was taken 27 days after the

    water receded.

    The contribut ion of submergence-tolerant (Sub1) rice varieties to food

    security in flood-prone rainfed lowland areas in Asia. Ismail, Singh,

    Singh, Dar, Mackill. 2013. Field Crops Research 152: 83 - 93

    Scuba Rice : a case study

    http://www.youtube.com/watch?feature=player_detailpage&v=shCHe1eAQoQ

    http://www.youtube.com/watch?v=apWCqcury90

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    Fig. 3 Yield of Samba Mahsuri and Samba Mahsuri-Sub1 after variable durations of

    submergence in farmers fields. Data are from farmers in Uttar Pradesh, India, during the

    wet season of 2011 ( n = 59).

    Website for s\detailed stories of SUB1and accelerated genetic improvement of crops.

    http://www.authorstream.com/Presentation/aSGuest10

    8849-1136509-marker-assisted-breeding/

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    0.001 mm

    10 mm

    Genetics asks:

    Why are children like their parents?

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    0.001 mm

    10 mm

    Genetics asks:

    Why are children like their parents?

    Why are children different from their parents?

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    Tools of Genetic Analysis

    Mutation

    Crosses

    Biochemistry

    Cytology

    DNA Structure

    DNA

    manipulation

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    Gregor Mednel at

    Augustinian Abbey, Brno, Bohemia

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    I. Rules of inheritance (of genes)

    a. are inferred from PATTERNS of gene

    transmission from one generation to the next

    b. are used, once known,to study nature and function of genes

    to deduce individual genes properties

    to predict offspring types

    II. Biochemical study of gene function gives more

    precise understanding of gene action.

    GENETICS

    Avery, 1944

    Mendel, 1865

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    Genetics: careful examination of CROSSES

    Parent 1genes

    traits

    Parent 2

    genes

    traits

    Mating

    n offspring:1: genes / traits

    2: genes / traits

    3: genes / traits4: genes / traits

    5: genes / traits

    . . .

    n: genes / traits

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    DNA ----> RNA ----> PROTEIN

    New fig 1-9 here!

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    RNA ----> PROTEIN

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    Note:

    in week 1 (only),

    we have three lectures

    and no Discussion sections

    ?

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    Where are TA Office Hours held?

    A LC-A1

    B SCE CafeteriaC BSB Cafeteria

    D SLC Darwin

    E BSB Cafeteria

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    Where are my Wednesday Office Office Hours held?

    A LC-A1

    B SCE CafeteriaC BSB Cafeteria

    D SLC Darwin

    E BSB Cafeteria

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    Where does class meet this Friday?

    A No lecture, only disc. SectionsB LC-A1

    C Giordanos

    D BSB Cafeteria

    E SES 250

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    ?

    What should you always bring to class?

    A Hat and Gloves

    B Textbook

    C Lecture notes

    D i>Clicker remote

    E C and D

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    ?

    Have you completed General Chemistry(112/114 or 116/118)?

    A Completed

    B This semester

    C Not yet

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    ?

    Have you completed Organic Chemistry (232/234)?

    A Completed

    B This semester

    C Not yet

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    ?

    Have you completed Introductory Physics?

    A Completed

    B This semester

    C Not yet

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    ?

    Have you completed Bios 222 Cell Biology?

    A Completed

    B This semester

    C Not yet

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    ?

    Where are test answer keys posted?

    A LC-A1

    B SEL 3289

    C SLE

    D MBRB

    E Addams Hall

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    ?

    How many of your classes have used i>Clickers?

    A None

    B 1

    C 2 or 3D 4 or 5

    E More than 5

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    BioS 220

    An i>clicker remote isrequired for this course.

    You can purchase it

    through the bookstore.

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    How will we

    use the clicker? I pose questions on the screen during

    lecture.

    You answer using your i>clicker remote.

    Class results are tallied.

    I display a graph with the class resultson the screen.

    We discuss the questions and answers.

    You get 1 point for participating and 4for answering correctly)!

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    How do you vote?

    Turn on the clicker by

    pressing the bottom On/Off button.

    A blue Power light will

    appear at the top of the

    remote.

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    How do you vote?

    When I ask a question in

    class (and start thetimer), select A, B, C, D,or E as your vote.

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    How do you know your

    vote was received?Check your Vote Status Light:

    Green light = your vote was sent

    AND received.Red flashing light = you need to vote

    again.

    Not sure you saw the light? Just

    vote again.

    Want to change your vote? You can

    vote again as long as the timer is stillgoing.

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    Registering your i>clicker

    You can earn points for your i>clickerresponses [for participation and/oranswering questions correctly].

    Until you register your i>clicker, yourresponses are tied to your clicker remote ID

    (located on the back of your clicker), ratherthan to you.

    When you do register, your previously

    recorded voting responses will be assignedto you.

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    Registeringyour i>clicker unit

    1. Go to BlackBoard.2. Go to Bio 220.3. Under Tools:4. Enter your iClicker

    serial number.

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    Other tips If you bought a used clicker, replace the batteries.

    Register your clicker by January 21.

    Before using a new clicker for the first t ime, pull the

    plastic tab out of the battery compartment.

    Bring your clicker to class every day!

    Make sure your remote is on when voting!

    Check out www.iclicker.com for FAQs.

    Contact [email protected] for help.