blue biotechnology new opportunities for eu · 2014-04-22 · blue biotechnology: vision for the...
TRANSCRIPT
Blue
biotechnology new opportunities
for EU
Limits, achievements
and perspectives
J. QUERELLOU, PhDIfremer, France
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What is blue biotechnology?
Marine livingresources
Products
BiotechnologyToolbox:- biodiscovery-
mol. biology
-
biochemistry
- microbiology- …omics-
etc.
Aquaculture
-
Drugs
-
Elicitors
- Biofuels-
Food
- Enzymes-
Biopolymers
- Organic
compounds-
Basic research
- Ecosystem
Management-
Bioremediation
Services
Global market: B€
1.9Annual
growth: 10%
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Blue biotechnology and food issue?
1. Optimisation of aquaculture production systems -
omics
applied
to aquaculture
-
high
opportunities
of transgenic
products
BUT?-
improved
microbial
control of farming
and health
-
quality/traceability/management of fish/shellfish
2. Optimisation of aquaculture products
contents for health-
beneficial
effects
of sea-food
-
optimisation of composition through
control of feed
quality
-
production of neutraceuticals
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Blue biotechnology
and energy
issue?1.
Microbial
Enhanced
Oil
Recovery
(MEOR)?
-
huge
potential
and high
economical
impacts-
controversial
results
and no clear
strategy
in Europe
-
future policy
to be
clarified
and recommendations for research
discussed
2. Marine products
for the second biofuel generation?-
Enzymes from
marine organisms
degrading
lignocellulosic
products-
Integration
of marine enzymes in industrial
process
3. MB and the third
biofuel generation
based
on microalgae-
High interest
to produce
biodiesel
-
Initiatives in R&D in the USA and Europe-
Economical
en environmental
sustainability?
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Blue biotechnology and health issue?
1.
Achievements
of the last 20 years-
Prialt™, Yondelis, and close to 20 compounds
under
trials-
Renewal
of interest
for natural
products
2. But many
constraints
and challenges-
legal
aspects, access, property
rights, IP
-
quality
of marine resources, id, sustainab.-
dereplication and shared
information
-
strutural
costs
from
marine products-
strategies
of SMEs
and big
pharmas
3. Antibioresistance
and deficit
of novel antibiotics: toward
post-antibiotic
era?
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Blue biotechnology
and environmental
issues?
1. Biofouling/antifouling- critical env. issue and huge economic importance- promising results but no commercial hits- need for research and integration of green AF and nanostructured coating
2. Detection of marine bacteria, viruses, toxic compounds- active community for designing molecular tools
DNA probes, PCR solutions, SPR in situ etc…3. Monitoring of chemicals
- need for efficient biological assessment tools- model organisms as integrating tools?
4. Bioremediation- oil spills: progress and limits. Policies?
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Blue biotechnology as a source of innovative
products?
1.
Proteins
and enzymes (notably
extremophiles)-
Large range of applications: white biotech, feed,
energy, environment, etc.-
Need
for improved
high
throughput
direct
screening from
crude
sample2. Biopolymers
(EPS, PHA, etc.)
-
Large range of applications: cosmetics, health, bioremediation, etc.
3. Biomaterials-
Novel
field
of research
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Blue biotechnology: vision for the future
By 2020 European Union will develop and apply advanced tools,
platforms and infrastructures and support to Marine Biotechnology to provide a significant contribution to addressing key societal challenges of the next decades in the areas of food and energy, development of novel drugs and treatments for human health and the sustainable use and management of the seas and oceans.
- Naive if not supported by an appropriate strategy and a strong implementation plan and constant support of all key players
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Blue biotechnology what
conditions for success?
-
Access to resources -
property
rights
in EEZ and the zone and IP
- no common
policy
except
general
trend to exclusive protection - sustainability
of resources
- shared
information and dereplication
-Shared
or distributed
infrastructures and equipments- Network of marine stations (ASSEMBLE and EUROFLEETS…)- Omics
infrastructures
- Biobanks
and biological
resources
centres
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Blue biotechnology: what strategy?Establish
completely
new mechanisms
and policies
to circumvent
the high
risks
of investments
in critical
novel
drugs
from
marine resources, notably
antibiotics
Improve
policies
in property
rights
and IP
Develop
a common
European position on regulations
of access
benefit
sharing
and exploitation
of marine genetic
resources
Support the emergence
of joint research
groups acad/industry
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Blue biotechnology challenge
Special
thanks
to Jan-Bart Calewaert, ESF
and MB WG members