NURS 315/501 Bootcamp

Lecture:

Cardiovascular Function and Disorders

Cardiovascular Function

Compare and contrast the pulmonary versus the systemic vascular system.

Cardiovascular Function Describe the

determinants of blood pressure.

Compare and contrast the differences in diastole and systole in relation to volume, electrical activity, and heart sounds.

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Cardiovascular Function Define Cardiac

Output ( CO). Describe the Frank

Starling Law mechanism to optimize preload.

What are the major determinants of afterload?

Describe the relationship between cardiac output and afterload.

Name and describe the determinants of contractility.

Autoregulation Explain the short-

term regulatory influence of: Local tissue ANS Baroreceptors/

chemoreceptors Humoral mechanism

On blood pressure

Hypertension Discuss the long term manisfestations of

HTN on: Heart Kidneys Brain Peripheral vasculature Retina

Describe the treatment algorithm for HTN.

Orthostatic Hypotension Explain the

physiological mechanism for orthostatic hypotension.

Pharmacotherapy for HTN Diuretics

Draw a nephron Describe the sites of

action of the different types of diuretics

Describe their MOA. Name potential drug

interactions with the use of diuretics.

ACE Inhibitors Describe their MOA Describe common

adverse effects. Identify potential

drug interactions.

Pharmacotherapy for HTN Angiotensin II

Receptor blocker Describe the MOA Describe adverse

effects. Identify potential

drug interactions.

Beta-Blockers Describe their MOA Compare and

contrast their effects on: Peripheral tissue Heart Lungs

Pharmacotherapy for HTN Calcium Channel

Blockers Describe their MOA Identify potential

drug interactions. Discuss relevant

patient teaching points.

Alpha-1 Antagonists Describe their MOA Compare and

contrast their effects on: Peripheral tissue Heart Lungs

Describe common adverse effects.

Pharmacotherapy for HTN Centrally Acting

Alpha-2 Agonists Describe their MOA Identify alternative

pharmacotherapeutic uses.

Name common adverse effects

Discuss relevant patient teaching points.

Pharmacotherapy for HTN

Name 3 direct acting vasodilators. What conditions are they used for?

What characterizes HTN emergency

Disorders of Arterial Circulation Describe the

metabolism of lipoproteins: VLDL LDL HDL

Identify the different types of anti-hyperlipidemic agents.

Disorders of Arterial Circulation Describe the MOA, common adverse

effects, and potential drug interactions for the following:1. Statins2. Fibric acid derivatives3. Ezetimibe (Zetia)4. Nicotinic acids5. Bile acid sequestrants