Case 6Case 6

TallinnTallinn NovNov 16, 2007 16, 2007

Sisko AnttilaSisko Anttila

!! MaleMale/67/67

!! fromfrom 1/05 1/05 shouldershoulder painpain

!! 8/05 8/05 gotgot extensiveextensive burnsburns in a in a firefire

!! skinskin transplantationstransplantations; ; detecteddetected a a skinskin

tumortumor

!! 2/06 2/06 TumorTumor fromfrom the the backback

CD34

Desmin

MIB-1 CK7

SMA

!! CRPCRP waswas highhigh and 2/05 in and 2/05 in searchsearch of of

infectioninfection a a CTCT waswas performedperformed

!! a a pleuralpleural tumortumor on the on the rightright side side withwith

invasioninvasion to to thoracicthoracic wallwall and and pleuralpleural fluidfluid

waswas detecteddetected

!! 3/06 3/06 transthoracictransthoracic biopsybiopsy

AE1/AE3

CK8

CK7

Also negative:

TTF-1

CD15

CK5/6

WT-1

Calretinin

!! DeathDeath 4/06 4/06

!! AutopsyAutopsy findingsfindings: : RightRight lunglung encasedencased withwith

hardhard, white , white tumortumor of of severalseveral cm in cm in

thicknessthickness, , extendingextending to to interlobarinterlobar and and

intercostalintercostal spacesspaces

!! LungLung samplesample for for asbestosasbestos fiberfiber analysisanalysis

OccupationalOccupational and and asbestos-asbestos-

exposureexposure historyhistory

!! machinemachine mechanicmechanic

!! for for severalseveral yearsyears workingworking at a at a powerpower plantplant

maymay havehave beenbeen exposedexposed to to asbestosasbestos

!! LungLung fiberfiber analysisanalysis::

26 26 millionmillion fibersfibers/g /g d-wd-w ( (94%94% crocidolitecrocidolite,,

6%6% amositeamosite))

"" asbestos-aetiologyasbestos-aetiology of the of the presentpresent MM is MM is

veryvery likelylikely