cell n genetics 2010 inter 2 ref unib

8/16/2019 Cell n Genetics 2010 Inter 2 Ref UNIB

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Fifinela RaissaJeanne

Cell and genetics module 2011

• Skeletal muscle

• Nervous tissue (neuron)

• Specialized cells

Jeanne Adiwinata Pawitani!inela "aissa

#ept$ o! %istolog& '


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Skeletal muscle•

investments° *pim&sium + muscle + irregular

dense collagenous connectivetissue

° Perim&sium + !ascicles (,undles) -. dense

° *ndom&sium + muscle !i,er (cell) -reticular !i,er/ ,asal lamina eternal lamina

• cell° Skeletal muscle !i,ers + striated +

parallel

° Satellite cells

Sum,er medicalook$com


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Skeletal muscle

cells!i,ersSource3artner 2001

• #evelopment m&o,last + parallelend +end !used myotube

– !ormed m&o!i,ril skeletalmuscle !i,er

• S4ape long/ tu,ular + 5 10-1006m

• 7etween !i,ers endom&sium 8continuous capillaries + parallel to!i,er

• Skeletal muscle !i,er + non,ranc4ing -striated -

multinucleated• Nuclei + perip4er& + in a row +

inside cell mem,rane(sarcolemma)


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Sarcoplasm contains *'

•

A lot o! m&o!i,ril 5-1-2 6m +longitudinal +along t4e !i,er + regularl& arranged

striation in longitudinal section

° A ,and + (anisotropic on polarized lig4t dark )

° ,and+ (isotropic on polarized lig4t lig4t)

• Sarcoplasmic reticulum 9 smoot4 sur!ace

endoplasmic reticulum

• Sarcolemma invagination : tu,ule

(transverse tu,ule)


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Source3artner 2001


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Satellite cells

• Satellite cells 9 regenerative cells

• Small cell + location s4allow depression

+ muscle cell;s sur!ace

• *ternal lamina + s4ared wit4 muscle

cell < inside eternal lamina

• Nucleus-one - = dense - = coarse


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"egeneration - muscles

• Skeletal muscle + regeneration (8)° Skeletal muscle !i,er > mitosis

° Satellite cells

• n?ur& satellite cells - mitosis + 4&perplasia• At muscle ,uilding satellite cell + muscle !i,er

-!usion mass increase 4&pertrop4&

• Cardiac muscle - > regeneration/ !i,ro,last +

connective tissue (scar)• Smoot4 muscle + regeneration (8)


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"egeneration + smoot4 muscle

• n?ur& !ormation o! new !i,ers

° 'itosis + smoot4 muscle !i,er (3 tr$/ urin$ tr$)

° #i!!erentiation - peric&te + ,lood vessel

• terus +pregnant + smoot4 muscle

° 4&perplasia - mitosis

° 4&pertrop4&


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Nerve tissue

Neurons

Supporting cells (glial cells)


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Neurons• Cell ,od& (soma/

perikar&on) + nucleus + nucleolus prominant

• #endrite (multiple)

° Nissl ,odies

° 7ranc4ing

• Aon (single) + long -

,ranc4ing

° Aon %illock ° Aon terminals/ end

,ul,s/ terminal ,outons

< s&napse


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3lial cells

• Astroc&tes

° i,rous

° Protoplasmatic• @ligodendroglia

• 'icroglia

•*pend&mal cells

• Sc4wann cells


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@ligodendroglia

Sc4wann cell


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Specialized

cells


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Specialized cells

• Protein secreting cells

• Steroid secreting cells

• Neuroendocrine cells

• Cells in organs < ot4er modules


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Protein secreting

cells Source• *$ c4ie! cells (stomac4)/acinar cells (pancreas)

• S4ape columnar/truncated p&ramid/ etc

• 7asal c&toplasm -,asop4ilic° Nucleus

° "ic4 in "*"/ pol&some

•

Apical c&toplasm -acidop4ilic° Secretor& granules +

proenz&me (z&mogen)


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Steroid secreting cells

• * spongioc&tes

(adrenal corte)

• S4ape pol&4edral• C&toplasm

° *tensive network o!

S*"

° ipid droplets +

appear vacuolated


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Neuroendocrine

cells

• Argenta!!in/ arg&rop4ilic +

silver staining

• AP#9 amine precursoruptake decar,o&lation

• #N*S9 di!!use

neuroendocrine s&stem

• ocation epit4eliumglands +s&stems

• Secretor& granules +at ,asal

c&toplasm near ,lood vessel

• * cells in adrenal medulla


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Source o! !igures

• 3artner P/ %iatt J$ Color tet,ook o!

%istolog&/ 2nd ed$

P4iladelp4iaSaundersB2001• %istolog& image review

• awcett #/ Jens4 "P$ 7loom D

awcett;s concise 4istolog&/ 2nd ed$ondonArnoldB2002


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:4e endE

cell n genetics 2010 inter 2 ref unib

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